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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116018140
log Bayes Factor = 24.9673
Chromosome 2   position 106,054,384  (GRCh37) Explore rs116018140 on Ensembl!
Variant rs116018140 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
M75 Shoulder lesions
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
I50 Heart failure
0.989 0.011 0.000
Chapter XI Diseases of the digestive system
0.988 0.012 0.000
Chapter II Neoplasms
0.984 0.016 0.000
I25.2 Old myocardial infarction
0.984 0.016 0.000
M75.1 Rotator cuff syndrome
0.984 0.016 0.000
S60-S69 Injuries to the wrist and hand
0.981 0.019 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.980 0.020 0.000
I44 Atrioventricular and left bundle-branch block
0.978 0.022 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.973 0.027 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.973 0.027 0.000
I47 Paroxysmal tachycardia
0.972 0.028 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.972 0.028 0.000
I50.9 Heart failure, unspecified
0.969 0.031 0.000
Z85 Personal history of malignant neoplasm
0.967 0.033 0.000
C79 Secondary malignant neoplasm of other sites
0.967 0.033 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.963 0.037 0.000
E70-E90 Metabolic disorders
0.950 0.050 0.000
G40-G47 Episodic and paroxysmal disorders
0.945 0.055 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.944 0.056 0.000
I21.4 Acute subendocardial myocardial infarction
0.943 0.057 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.943 0.057 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.941 0.059 0.000
K90-K93 Other diseases of the digestive system
0.940 0.060 0.000
Z96 Presence of other functional implants
0.934 0.066 0.000
I25.1 Atherosclerotic heart disease
0.932 0.068 0.000
K55-K64 Other diseases of intestines
0.931 0.069 0.000
I49 Other cardiac arrhythmias
0.930 0.070 0.000
I51 Complications and ill-defined descriptions of heart disease
0.928 0.072 0.000
I44.7 Left bundle-branch block, unspecified
0.927 0.073 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.925 0.075 0.000
K92 Other diseases of digestive system
0.923 0.077 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.922 0.078 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.922 0.078 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.921 0.079 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.919 0.081 0.000
K58 Irritable bowel syndrome
0.918 0.082 0.000
G40 Epilepsy
0.917 0.083 0.000
K70-K77 Diseases of liver
0.912 0.088 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.912 0.088 0.000
E20-E35 Disorders of other endocrine glands
0.909 0.091 0.000
I47.2 Ventricular tachycardia
0.908 0.092 0.000
C15-C26 Malignant neoplasms of digestive organs
0.905 0.095 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.903 0.097 0.000
K92.1 Melaena
0.902 0.098 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.902 0.098 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.902 0.098 0.000
W00-W19 Falls
0.900 0.100 0.000
M75.5 Bursitis of shoulder
0.896 0.104 0.000
I45 Other conduction disorders
0.893 0.107 0.000
I42 Cardiomyopathy
0.892 0.108 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.892 0.108 0.000
Chapter XIV Diseases of the genitourinary system
0.890 0.110 0.000
M75.2 Bicipital tendinitis
0.890 0.110 0.000
S90-S99 Injuries to the ankle and foot
0.889 0.111 0.000
G90-G99 Other disorders of the nervous system
0.889 0.111 0.000
O60-O75 Complications of labour and delivery
0.887 0.113 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.887 0.113 0.000
I47.1 Supraventricular tachycardia
0.886 0.114 0.000
R00 Abnormalities of heart beat
0.884 0.116 0.000
I21.9 Acute myocardial infarction, unspecified
0.880 0.120 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.874 0.126 0.000
Chapter V Mental and behavioural disorders
0.873 0.127 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.872 0.128 0.000
Chapter VIII Diseases of the ear and mastoid process
0.871 0.129 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.871 0.129 0.000
G20-G26 Extrapyramidal and movement disorders
0.868 0.132 0.000
C64-C68 Malignant neoplasms of urinary tract
0.868 0.132 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.868 0.132 0.000
K60 Fissure and fistula of anal and rectal regions
0.867 0.133 0.000
M65-M68 Disorders of synovium and tendon
0.866 0.134 0.000
I50.1 Left ventricular failure
0.865 0.135 0.000
I51.8 Other ill-defined heart diseases
0.865 0.135 0.000
S40-S49 Injuries to the shoulder and upper arm
0.864 0.135 0.000
I49.9 Cardiac arrhythmia, unspecified
0.864 0.136 0.000
C79.2 Secondary malignant neoplasm of skin
0.861 0.139 0.000
M15-M19 Arthrosis
0.859 0.141 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.856 0.144 0.000
Z88.0 Personal history of allergy to penicillin
0.856 0.144 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.854 0.146 0.000
R00.0 Tachycardia, unspecified
0.854 0.146 0.000
I22 Subsequent myocardial infarction
0.854 0.146 0.000
S64 Injury of nerves at wrist and hand level
0.851 0.149 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.850 0.150 0.000
N17-N19 Renal failure
0.849 0.151 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.848 0.152 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.848 0.152 0.000
K92.0 Haematemesis
0.847 0.153 0.000
I44.2 Atrioventricular block, complete
0.846 0.154 0.000
Z80 Family history of malignant neoplasm
0.846 0.154 0.000
Z96.1 Presence of intraocular lens
0.845 0.155 0.000
C77.2 Intra-abdominal lymph nodes
0.844 0.156 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.843 0.157 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.841 0.159 0.000
M75.4 Impingement syndrome of shoulder
0.840 0.160 0.000
M19 Other arthrosis
0.840 0.160 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.839 0.161 0.000
I38 Endocarditis, valve unspecified
0.838 0.162 0.000
I34 Nonrheumatic mitral valve disorders
0.835 0.165 0.000
I44.0 Atrioventricular block, first degree
0.830 0.170 0.000
C18 Malignant neoplasm of colon
0.829 0.171 0.000
S61 Open wound of wrist and hand
0.829 0.171 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.829 0.171 0.000
H80-H83 Diseases of inner ear
0.829 0.171 0.000
Q21 Congenital malformations of cardiac septa
0.828 0.172 0.000
Z94 Transplanted organ and tissue status
0.825 0.175 0.000
Z96.8 Presence of other specified functional implants
0.824 0.176 0.000
K76 Other diseases of liver
0.824 0.176 0.000
Z95.0 Presence of cardiac pacemaker
0.821 0.179 0.000
I51.9 Heart disease, unspecified
0.820 0.180 0.000
I25.5 Ischaemic cardiomyopathy
0.820 0.180 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.820 0.180 0.000
K02 Dental caries
0.820 0.180 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.818 0.182 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.817 0.183 0.000
E78.0 Pure hypercholesterolaemia
0.814 0.186 0.000
N40-N51 Diseases of male genital organs
0.814 0.186 0.000
K60.3 Anal fistula
0.813 0.187 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.812 0.188 0.000
S20-S29 Injuries to the thorax
0.812 0.188 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.811 0.189 0.000
M19.9 Arthrosis, unspecified
0.811 0.189 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.811 0.189 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.810 0.190 0.000
G30-G32 Other degenerative diseases of the nervous system
0.810 0.190 0.000
N17 Acute renal failure
0.810 0.190 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.809 0.191 0.000
E83 Disorders of mineral metabolism
0.809 0.191 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.807 0.193 0.000
O63 Long labour
0.806 0.194 0.000
W19 Unspecified fall
0.806 0.194 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.804 0.196 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.803 0.197 0.000
T79-T79 Certain early complications of trauma
0.798 0.202 0.000
S10-S19 Injuries to the neck
0.797 0.203 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.795 0.205 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.795 0.205 0.000
Q21.1 Atrial septal defect
0.795 0.205 0.000
I46 Cardiac arrest
0.793 0.207 0.000
Z93 Artificial opening status
0.793 0.207 0.000
E86 Volume depletion
0.792 0.208 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.790 0.210 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.789 0.211 0.000
S92 Fracture of foot, except ankle
0.788 0.212 0.000
Z03.8 Observation for other suspected diseases and conditions
0.788 0.212 0.000
H81 Disorders of vestibular function
0.787 0.213 0.000
S00-S09 Injuries to the head
0.785 0.215 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.784 0.216 0.000
N25-N29 Other disorders of kidney and ureter
0.784 0.216 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.783 0.217 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.783 0.217 0.000
S69 Other and unspecified injuries of wrist and hand
0.782 0.218 0.000
N17.9 Acute renal failure, unspecified
0.782 0.218 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.781 0.219 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.780 0.220 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.780 0.220 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.779 0.221 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.779 0.221 0.000
G40.9 Epilepsy, unspecified
0.778 0.222 0.000
I45.9 Conduction disorder, unspecified
0.778 0.222 0.000
G20 Parkinson's disease
0.777 0.223 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.777 0.223 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.777 0.223 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.776 0.224 0.000
K13 Other diseases of lip and oral mucosa
0.776 0.224 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.775 0.225 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.774 0.226 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.774 0.226 0.000
M45-M49 Spondylopathies
0.774 0.226 0.000
C79.6 Secondary malignant neoplasm of ovary
0.773 0.227 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.771 0.229 0.000
O36 Maternal care for other known or suspected foetal problems
0.771 0.229 0.000
M79.8 Other specified soft tissue disorders
0.770 0.230 0.000
E00-E07 Disorders of thyroid gland
0.770 0.230 0.000
M79.6 Pain in limb
0.769 0.231 0.000
M75.0 Adhesive capsulitis of shoulder
0.769 0.231 0.000
S80-S89 Injuries to the knee and lower leg
0.768 0.232 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.766 0.234 0.000
K83 Other diseases of biliary tract
0.766 0.234 0.000
T66-T78 Other and unspecified effects of external causes
0.765 0.235 0.000
N41 Inflammatory diseases of prostate
0.764 0.236 0.000
N00-N08 Glomerular diseases
0.764 0.236 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.763 0.237 0.000
N50 Other disorders of male genital organs
0.762 0.238 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.762 0.238 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.761 0.239 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.760 0.240 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
W07 Fall involving chair
0.758 0.242 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.758 0.242 0.000
I33 Acute and subacute endocarditis
0.757 0.243 0.000
X20-X29 Contact with venomous animals and plants
0.755 0.245 0.000
N60-N64 Disorders of breast
0.755 0.245 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.754 0.245 0.000
C78.7 Secondary malignant neoplasm of liver
0.754 0.246 0.000
M77 Other enthesopathies
0.754 0.246 0.000
C60-C63 Malignant neoplasms of male genital organs
0.754 0.246 0.000
K10 Other diseases of jaws
0.753 0.247 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.752 0.248 0.000
O80-O84 Delivery
0.751 0.249 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.749 0.250 0.000
I50.0 Congestive heart failure
0.748 0.252 0.000
X60-X84 Intentional self-harm
0.748 0.252 0.000
S32 Fracture of lumbar spine and pelvis
0.747 0.253 0.000
K02.9 Dental caries, unspecified
0.746 0.253 0.000
K70 Alcoholic liver disease
0.746 0.254 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.746 0.254 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.745 0.255 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.745 0.255 0.000
H81.0 Meniere's disease
0.744 0.256 0.000
O40 Polyhydramnios
0.744 0.256 0.000
Z82.3 Family history of stroke
0.744 0.256 0.000
I24 Other acute ischaemic heart diseases
0.743 0.257 0.000
C15 Malignant neoplasm of oesophagus
0.743 0.257 0.000
M91-M94 Chondropathies
0.743 0.257 0.000
R04 Haemorrhage from respiratory passages
0.742 0.257 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.742 0.258 0.000
I45.1 Other and unspecified right bundle-branch block
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
C77.1 Intrathoracic lymph nodes
0.740 0.260 0.000
I30 Acute pericarditis
0.739 0.261 0.000
S67 Crushing injury of wrist and hand
0.739 0.261 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.738 0.262 0.000
Z95.1 Presence of aortocoronary bypass graft
0.738 0.262 0.000
R06 Abnormalities of breathing
0.736 0.264 0.000
S60 Superficial injury of wrist and hand
0.736 0.264 0.000
S68 Traumatic amputation of wrist and hand
0.733 0.267 0.000
C25 Malignant neoplasm of pancreas
0.733 0.267 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.732 0.268 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.732 0.268 0.000
K76.9 Liver disease, unspecified
0.732 0.268 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.732 0.268 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.732 0.268 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
O63.1 Prolonged second stage (of labour)
0.731 0.269 0.000
E27 Other disorders of adrenal gland
0.731 0.269 0.000
M65 Synovitis and tenosynovitis
0.731 0.269 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.730 0.270 0.000
Y52 Agents primarily affecting the cardiovascular system
0.730 0.270 0.000
S70-S79 Injuries to the hip and thigh
0.730 0.270 0.000
G44 Other headache syndromes
0.729 0.271 0.000
O42 Premature rupture of membranes
0.729 0.271 0.000
E20 Hypoparathyroidism
0.728 0.272 0.000
K07 Dentofacial anomalies [including malocclusion]
0.727 0.272 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.727 0.273 0.000
I42.6 Alcoholic cardiomyopathy
0.727 0.273 0.000
N50.8 Other specified disorders of male genital organs
0.727 0.273 0.000
V10-V19 Pedal cyclist injured in transport accident
0.727 0.273 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.726 0.274 0.000
C51-C58 Malignant neoplasms of female genital organs
0.726 0.274 0.000
Z96.0 Presence of urogenital implants
0.726 0.274 0.000
S62 Fracture at wrist and hand level
0.726 0.274 0.000
N18 Chronic renal failure
0.726 0.274 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.725 0.275 0.000
K60.1 Chronic anal fissure
0.724 0.276 0.000
C18.0 Caecum
0.723 0.277 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.722 0.278 0.000
S64.4 Injury of digital nerve of other finger
0.722 0.278 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.721 0.279 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.720 0.280 0.000
E83.5 Disorders of calcium metabolism
0.719 0.281 0.000
I49.0 Ventricular fibrillation and flutter
0.719 0.281 0.000
K09 Cysts of oral region, not elsewhere classified
0.719 0.281 0.000
W20-W49 Exposure to inanimate mechanical forces
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I34.0 Mitral (valve) insufficiency
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.716 0.284 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.284 0.000
O62 Abnormalities of forces of labour
0.716 0.284 0.000
M71 Other bursopathies
0.716 0.284 0.000
M79.62 Pain in limb (Upper arm)
0.715 0.285 0.000
M75.8 Other shoulder lesions
0.715 0.285 0.000
M75.9 Shoulder lesion, unspecified
0.715 0.285 0.000
W19.9 Unspecified place
0.715 0.285 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.715 0.285 0.000
Z89 Acquired absence of limb
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
O47 False labour
0.714 0.286 0.000
S42 Fracture of shoulder and upper arm
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.286 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.713 0.287 0.000
K83.1 Obstruction of bile duct
0.712 0.288 0.000
R94 Abnormal results of function studies
0.712 0.288 0.000
R07 Pain in throat and chest
0.710 0.290 0.000
Z93.6 Other artificial openings of urinary tract status
0.709 0.291 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.709 0.291 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.292 0.000
E78.5 Hyperlipidaemia, unspecified
0.707 0.293 0.000
S61.8 Open wound of other parts of wrist and hand
0.707 0.293 0.000
G56 Mononeuropathies of upper limb
0.707 0.293 0.000
I42.9 Cardiomyopathy, unspecified
0.706 0.294 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
M19.0 Primary arthrosis of other joints
0.705 0.295 0.000
G95 Other diseases of spinal cord
0.705 0.295 0.000
E22 Hyperfunction of pituitary gland
0.705 0.295 0.000
K11 Diseases of salivary glands
0.704 0.296 0.000
G96 Other disorders of central nervous system
0.703 0.297 0.000
S65 Injury of blood vessels at wrist and hand level
0.703 0.297 0.000
I49.5 Sick sinus syndrome
0.703 0.297 0.000
R06.0 Dyspnoea
0.703 0.297 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.703 0.297 0.000
R41.0 Disorientation, unspecified
0.702 0.298 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.702 0.298 0.000
R00.2 Palpitations
0.702 0.298 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.702 0.298 0.000
I44.6 Other and unspecified fascicular block
0.701 0.298 0.000
I44.5 Left posterior fascicular block
0.701 0.298 0.000
I44.4 Left anterior fascicular block
0.701 0.298 0.000
I44.3 Other and unspecified atrioventricular block
0.701 0.298 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.701 0.299 0.000
K75 Other inflammatory liver diseases
0.701 0.299 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.701 0.299 0.000
E40-E46 Malnutrition
0.701 0.299 0.000
M80-M85 Disorders of bone density and structure
0.700 0.300 0.000
I46.0 Cardiac arrest with successful resuscitation
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
I49.8 Other specified cardiac arrhythmias
0.699 0.301 0.000
M20-M25 Other joint disorders
0.698 0.302 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.698 0.302 0.000
C77.9 Lymph node, unspecified
0.697 0.302 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.697 0.302 0.000
O85-O92 Complications predominantly related to the puerperium
0.697 0.303 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.697 0.303 0.000
I47.0 Reentry ventricular arrhythmia
0.697 0.303 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.697 0.303 0.000
S90 Superficial injury of ankle and foot
0.696 0.303 0.000
G62 Other polyneuropathies
0.696 0.304 0.000
R04.2 Haemoptysis
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.695 0.305 0.000
E04 Other non-toxic goitre
0.694 0.306 0.000
M67 Other disorders of synovium and tendon
0.694 0.306 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.694 0.306 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.694 0.306 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.694 0.306 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.694 0.306 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.693 0.306 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.693 0.307 0.000
S50-S59 Injuries to the elbow and forearm
0.693 0.307 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.693 0.307 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.693 0.307 0.000
W19.2 School, other institution and public administrative area
0.693 0.307 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.692 0.308 0.000
K55 Vascular disorders of intestine
0.692 0.308 0.000
R13 Dysphagia
0.691 0.309 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.690 0.310 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.690 0.310 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.690 0.310 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.690 0.310 0.000
Z82.2 Family history of deafness and hearing loss
0.690 0.310 0.000
Z82.1 Family history of blindness and visual loss
0.690 0.310 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.690 0.310 0.000
Z04 Examination and observation for other reasons
0.690 0.310 0.000
Z94.8 Other transplanted organ and tissue status
0.689 0.311 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.689 0.311 0.000
K85 Acute pancreatitis
0.689 0.311 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.688 0.312 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.688 0.312 0.000
M75.3 Calcific tendinitis of shoulder
0.687 0.313 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.687 0.313 0.000
C18.9 Colon, unspecified
0.686 0.314 0.000
Y40 Systemic antibiotics
0.684 0.315 0.000
E89.0 Postprocedural hypothyroidism
0.684 0.316 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.684 0.316 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.683 0.317 0.000
I42.0 Dilated cardiomyopathy
0.683 0.317 0.000
H60-H62 Diseases of external ear
0.683 0.317 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.683 0.317 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.682 0.317 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.682 0.318 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.682 0.318 0.000
E85 Amyloidosis
0.681 0.319 0.000
E84 Cystic fibrosis
0.681 0.319 0.000
E79 Disorders of purine and pyrimidine metabolism
0.681 0.319 0.000
E77 Disorders of glycoprotein metabolism
0.681 0.319 0.000
E76 Disorders of glycosaminoglycan metabolism
0.681 0.319 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.681 0.319 0.000
E74 Other disorders of carbohydrate metabolism
0.681 0.319 0.000
E73 Lactose intolerance
0.681 0.319 0.000
E72 Other disorders of amino-acid metabolism
0.681 0.319 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.681 0.319 0.000
E70 Disorders of aromatic amino-acid metabolism
0.681 0.319 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.681 0.319 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.680 0.320 0.000
Q43 Other congenital malformations of intestine
0.680 0.320 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.679 0.321 0.000
K60.0 Acute anal fissure
0.679 0.321 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.678 0.322 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.678 0.322 0.000
G41 Status epilepticus
0.678 0.322 0.000
C18.5 Splenic flexure
0.678 0.322 0.000
M19.98 Arthrosis, unspecified (Other)
0.677 0.323 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.676 0.324 0.000
Q80-Q89 Other congenital malformations
0.676 0.324 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.676 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.676 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.676 0.324 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.676 0.324 0.000
Q00-Q07 Congenital malformations of the nervous system
0.676 0.324 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.676 0.324 0.000
M79.0 Rheumatism, unspecified
0.676 0.324 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.676 0.324 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.675 0.325 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.675 0.325 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.674 0.326 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.674 0.326 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.674 0.326 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.673 0.327 0.000
Q50-Q56 Congenital malformations of genital organs
0.672 0.328 0.000
C62 Malignant neoplasm of testis
0.672 0.328 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.672 0.328 0.000
Z02 Examination and encounter for administrative purposes
0.671 0.329 0.000
R03.1 Nonspecific low blood-pressure reading
0.670 0.330 0.000
G93 Other disorders of brain
0.670 0.330 0.000
Z96.9 Presence of functional implant, unspecified
0.670 0.330 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.670 0.330 0.000
Z96.4 Presence of endocrine implants
0.670 0.330 0.000
Z96.3 Presence of artificial larynx
0.670 0.330 0.000
Z96.2 Presence of otological and audiological implants
0.670 0.330 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.668 0.331 0.000
I05-I09 Chronic rheumatic heart diseases
0.668 0.331 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.668 0.332 0.000
N41.1 Chronic prostatitis
0.667 0.333 0.000
I49.2 Junctional premature depolarisation
0.667 0.333 0.000
I49.1 Atrial premature depolarisation
0.667 0.333 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.667 0.333 0.000
E23 Hypofunction and other disorders of pituitary gland
0.666 0.334 0.000
I51.6 Cardiovascular disease, unspecified
0.665 0.335 0.000
I51.5 Myocardial degeneration
0.665 0.335 0.000
I51.4 Myocarditis, unspecified
0.665 0.335 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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