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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116458312
log Bayes Factor = 13.1491
Chromosome 5   position 147,976,829  (GRCh37) Explore rs116458312 on Ensembl!
Variant rs116458312 is part of Cluster X0123

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.995 0.005 0.000
I60-I69 Cerebrovascular diseases
0.993 0.007 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.990 0.010 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.985 0.015 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.984 0.016 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.983 0.017 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
I63 Cerebral infarction
0.981 0.019 0.000
I77 Other disorders of arteries and arterioles
0.977 0.023 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.976 0.024 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.976 0.024 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
H80-H83 Diseases of inner ear
0.975 0.025 0.000
C34 Malignant neoplasm of bronchus and lung
0.975 0.025 0.000
T66-T78 Other and unspecified effects of external causes
0.968 0.032 0.000
Chapter X Diseases of the respiratory system
0.967 0.033 0.000
R54 Senility
0.966 0.034 0.000
Q60-Q64 Congenital malformations of the urinary system
0.965 0.035 0.000
J90-J94 Other diseases of pleura
0.965 0.035 0.000
H81 Disorders of vestibular function
0.965 0.035 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.965 0.035 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.962 0.038 0.000
J93 Pneumothorax
0.962 0.038 0.000
R60 Oedema, not elsewhere classified
0.959 0.041 0.000
C16 Malignant neoplasm of stomach
0.957 0.043 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.955 0.045 0.000
R25 Abnormal involuntary movements
0.955 0.045 0.000
H81.0 Meniere's disease
0.951 0.049 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.951 0.049 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.950 0.050 0.000
S00-S09 Injuries to the head
0.949 0.051 0.000
T78 Adverse effects, not elsewhere classified
0.945 0.055 0.000
I63.9 Cerebral infarction, unspecified
0.944 0.056 0.000
J93.9 Pneumothorax, unspecified
0.943 0.057 0.000
Q61 Cystic kidney disease
0.943 0.057 0.000
R60.0 Localised oedema
0.941 0.059 0.000
C34.9 Bronchus or lung, unspecified
0.939 0.061 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.936 0.064 0.000
I72 Other aneurysm
0.934 0.066 0.000
I77.1 Stricture of artery
0.927 0.073 0.000
I69 Sequelae of cerebrovascular disease
0.923 0.077 0.000
R59 Enlarged lymph nodes
0.920 0.080 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.919 0.081 0.000
C17 Malignant neoplasm of small intestine
0.919 0.081 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.914 0.086 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.914 0.086 0.000
S09 Other and unspecified injuries of head
0.910 0.090 0.000
R68 Other general symptoms and signs
0.909 0.091 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.907 0.093 0.000
Q61.3 Polycystic kidney, unspecified
0.897 0.103 0.000
T93 Sequelae of injuries of lower limb
0.896 0.104 0.000
I05-I09 Chronic rheumatic heart diseases
0.894 0.106 0.000
C16.0 Cardia
0.893 0.107 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.893 0.107 0.000
Chapter XX External causes of morbidity and mortality
0.892 0.108 0.000
T51 Toxic effect of alcohol
0.891 0.109 0.000
C34.3 Lower lobe, bronchus or lung
0.890 0.110 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.890 0.110 0.000
I74 Arterial embolism and thrombosis
0.890 0.110 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.890 0.110 0.000
E20-E35 Disorders of other endocrine glands
0.890 0.110 0.000
S09.9 Unspecified injury of head
0.881 0.119 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.879 0.121 0.000
J93.8 Other pneumothorax
0.876 0.124 0.000
F60-F69 Disorders of adult personality and behaviour
0.874 0.126 0.000
T78.3 Angioneurotic oedema
0.871 0.129 0.000
J92 Pleural plaque
0.867 0.133 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.863 0.137 0.000
I05 Rheumatic mitral valve diseases
0.862 0.138 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.861 0.139 0.000
T78.2 Anaphylactic shock, unspecified
0.861 0.139 0.000
C77.2 Intra-abdominal lymph nodes
0.860 0.140 0.000
Chapter VI Diseases of the nervous system
0.859 0.141 0.000
Q61.2 Polycystic kidney, adult type
0.857 0.143 0.000
F44 Dissociative [conversion] disorders
0.856 0.144 0.000
C16.9 Stomach, unspecified
0.856 0.144 0.000
T91 Sequelae of injuries of neck and trunk
0.855 0.145 0.000
T51.0 Ethanol
0.852 0.148 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.852 0.148 0.000
J91 Pleural effusion in conditions classified elsewhere
0.850 0.150 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.849 0.151 0.000
R25.3 Fasciculation
0.847 0.153 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.844 0.156 0.000
H80 Otosclerosis
0.843 0.157 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.843 0.157 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.841 0.159 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.837 0.163 0.000
C23 Malignant neoplasm of gallbladder
0.836 0.164 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.836 0.164 0.000
R25.1 Tremor, unspecified
0.835 0.165 0.000
F40 Phobic anxiety disorders
0.835 0.165 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.832 0.168 0.000
I78 Diseases of capillaries
0.829 0.170 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.829 0.171 0.000
T40.2 Other opioids
0.829 0.171 0.000
J93.1 Other spontaneous pneumothorax
0.828 0.172 0.000
I67 Other cerebrovascular diseases
0.823 0.177 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.819 0.181 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.819 0.181 0.000
R57 Shock, not elsewhere classified
0.818 0.182 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.818 0.182 0.000
C17.2 Ileum
0.817 0.183 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.815 0.185 0.000
C85.1 B-cell lymphoma, unspecified
0.812 0.188 0.000
J09-J18 Influenza and pneumonia
0.811 0.189 0.000
C82.2 Large cell, follicular
0.810 0.190 0.000
R47-R49 Symptoms and signs involving speech and voice
0.809 0.191 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.807 0.192 0.000
R59.0 Localised enlarged lymph nodes
0.803 0.197 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.803 0.197 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.803 0.197 0.000
I72.4 Aneurysm of artery of lower extremity
0.802 0.198 0.000
F60 Specific personality disorders
0.801 0.199 0.000
Q50-Q56 Congenital malformations of genital organs
0.800 0.200 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.800 0.200 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.799 0.201 0.000
J40-J47 Chronic lower respiratory diseases
0.798 0.202 0.000
I63.8 Other cerebral infarction
0.797 0.203 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.797 0.203 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.797 0.203 0.000
S10-S19 Injuries to the neck
0.796 0.204 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.793 0.207 0.000
R56 Convulsions, not elsewhere classified
0.793 0.207 0.000
R52 Pain, not elsewhere classified
0.793 0.207 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.792 0.208 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.791 0.209 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.790 0.210 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.789 0.211 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.789 0.211 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.789 0.211 0.000
H90-H95 Other disorders of ear
0.788 0.212 0.000
G90-G99 Other disorders of the nervous system
0.788 0.212 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.786 0.214 0.000
R25.2 Cramp and spasm
0.786 0.214 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.786 0.214 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.784 0.216 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.783 0.217 0.000
I05.9 Mitral valve disease, unspecified
0.783 0.217 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.781 0.219 0.000
Q00-Q07 Congenital malformations of the nervous system
0.780 0.220 0.000
I77.0 Arteriovenous fistula, acquired
0.780 0.220 0.000
H81.9 Disorder of vestibular function, unspecified
0.779 0.221 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.777 0.223 0.000
R59.9 Enlarged lymph nodes, unspecified
0.777 0.223 0.000
I72.9 Aneurysm of unspecified site
0.777 0.223 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.776 0.224 0.000
Q80-Q89 Other congenital malformations
0.776 0.224 0.000
E34 Other endocrine disorders
0.776 0.224 0.000
C77.9 Lymph node, unspecified
0.774 0.225 0.000
C82.0 Small cleaved cell, follicular
0.774 0.226 0.000
C34.0 Main bronchus
0.772 0.228 0.000
S00 Superficial injury of head
0.772 0.228 0.000
E00-E07 Disorders of thyroid gland
0.772 0.228 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.771 0.229 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.771 0.229 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
C77.8 Lymph nodes of multiple regions
0.769 0.231 0.000
J44 Other chronic obstructive pulmonary disease
0.769 0.231 0.000
X60-X84 Intentional self-harm
0.766 0.234 0.000
F45 Somatoform disorders
0.765 0.235 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.765 0.235 0.000
T59 Toxic effect of other gases, fumes and vapours
0.763 0.237 0.000
R68.8 Other specified general symptoms and signs
0.763 0.237 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.761 0.239 0.000
Q43 Other congenital malformations of intestine
0.760 0.240 0.000
F43 Reaction to severe stress, and adjustment disorders
0.758 0.242 0.000
H81.2 Vestibular neuronitis
0.758 0.242 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.758 0.242 0.000
R60.1 Generalised oedema
0.758 0.242 0.000
I05.0 Mitral stenosis
0.756 0.244 0.000
D00-D09 In situ neoplasms
0.755 0.245 0.000
T78.4 Allergy, unspecified
0.754 0.246 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.753 0.247 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.752 0.248 0.000
C77.1 Intrathoracic lymph nodes
0.752 0.248 0.000
T56 Toxic effect of metals
0.752 0.248 0.000
F40.2 Specific (isolated) phobias
0.752 0.248 0.000
R26 Abnormalities of gait and mobility
0.752 0.248 0.000
C25 Malignant neoplasm of pancreas
0.751 0.249 0.000
I69.3 Sequelae of cerebral infarction
0.751 0.249 0.000
F42 Obsessive-compulsive disorder
0.751 0.249 0.000
T40.6 Other and unspecified narcotics
0.750 0.250 0.000
S01 Open wound of head
0.749 0.251 0.000
H80.9 Otosclerosis, unspecified
0.749 0.251 0.000
C71 Malignant neoplasm of brain
0.748 0.252 0.000
I60 Subarachnoid haemorrhage
0.748 0.252 0.000
J92.9 Pleural plaque without asbestos
0.745 0.255 0.000
C17.9 Small intestine, unspecified
0.745 0.255 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.745 0.255 0.000
C34.2 Middle lobe, bronchus or lung
0.744 0.256 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.743 0.257 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.741 0.259 0.000
J60-J70 Lung diseases due to external agents
0.741 0.259 0.000
I72.3 Aneurysm of iliac artery
0.738 0.262 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.738 0.262 0.000
T93.2 Sequelae of other fractures of lower limb
0.735 0.265 0.000
R80 Isolated proteinuria
0.734 0.266 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.733 0.267 0.000
I72.8 Aneurysm of other specified arteries
0.733 0.267 0.000
T98 Sequelae of other and unspecified effects of external causes
0.731 0.269 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.731 0.269 0.000
V98-V99 Other and unspecified transport accidents
0.729 0.271 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.728 0.272 0.000
R47 Speech disturbances, not elsewhere classified
0.727 0.273 0.000
F44.5 Dissociative convulsions
0.726 0.274 0.000
C34.1 Upper lobe, bronchus or lung
0.726 0.274 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.726 0.274 0.000
S05 Injury of eye and orbit
0.726 0.274 0.000
J92.0 Pleural plaque with presence of asbestos
0.725 0.275 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.725 0.275 0.000
C17.0 Duodenum
0.724 0.275 0.000
Chapter XXII Codes for special purposes
0.723 0.277 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.723 0.277 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.723 0.277 0.000
T45.0 Antiallergic and antiemetic drugs
0.721 0.279 0.000
E06 Thyroiditis
0.720 0.280 0.000
C77.0 Lymph nodes of head, face and neck
0.720 0.280 0.000
I62 Other nontraumatic intracranial haemorrhage
0.718 0.282 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.718 0.282 0.000
D44.3 Pituitary gland
0.717 0.283 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.717 0.283 0.000
Q76 Congenital malformations of spine and bony thorax
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
W00-W19 Falls
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
E20 Hypoparathyroidism
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.284 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.715 0.285 0.000
Q35-Q37 Cleft lip and cleft palate
0.715 0.285 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.715 0.285 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.714 0.285 0.000
C95 Leukaemia of unspecified cell type
0.714 0.285 0.000
C94 Other leukaemias of specified cell type
0.714 0.285 0.000
C93 Monocytic leukaemia
0.714 0.285 0.000
C88 Malignant immunoproliferative diseases
0.714 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.714 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.286 0.000
R62 Lack of expected normal physiological development
0.714 0.286 0.000
R64 Cachexia
0.714 0.286 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.713 0.286 0.000
C18 Malignant neoplasm of colon
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.712 0.288 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
E29 Testicular dysfunction
0.711 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
C82.6 Cutaneous follicle centre lymphoma
0.710 0.290 0.000
C82.5 Diffuse follicle centre lymphoma
0.710 0.290 0.000
C82.4 Follicular lymphoma grade IIIb
0.710 0.290 0.000
C82.3 Follicular lymphoma grade IIIa
0.710 0.290 0.000
S50-S59 Injuries to the elbow and forearm
0.709 0.291 0.000
Q44.6 Cystic disease of liver
0.709 0.291 0.000
I67.9 Cerebrovascular disease, unspecified
0.709 0.291 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.709 0.291 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.293 0.000
G91 Hydrocephalus
0.707 0.293 0.000
J46 Status asthmaticus
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.705 0.295 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.705 0.295 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.705 0.295 0.000
C31 Malignant neoplasm of accessory sinuses
0.705 0.295 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.705 0.295 0.000
C37 Malignant neoplasm of thymus
0.705 0.295 0.000
C33 Malignant neoplasm of trachea
0.705 0.295 0.000
S80-S89 Injuries to the knee and lower leg
0.705 0.295 0.000
E21.0 Primary hyperparathyroidism
0.705 0.295 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.704 0.296 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.703 0.296 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.703 0.296 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.703 0.296 0.000
H81.1 Benign paroxysmal vertigo
0.702 0.298 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.702 0.298 0.000
I77.5 Necrosis of artery
0.700 0.300 0.000
I77.4 Coeliac artery compression syndrome
0.700 0.300 0.000
I77.3 Arterial fibromuscular dysplasia
0.700 0.300 0.000
I77.2 Rupture of artery
0.700 0.300 0.000
E50-E64 Other nutritional deficiencies
0.700 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
R59.1 Generalised enlarged lymph nodes
0.700 0.300 0.000
I05.1 Rheumatic mitral insufficiency
0.700 0.300 0.000
E28 Ovarian dysfunction
0.699 0.301 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.699 0.301 0.000
C34.8 Overlapping lesion of bronchus and lung
0.699 0.301 0.000
R47.8 Other and unspecified speech disturbances
0.698 0.302 0.000
I74.5 Embolism and thrombosis of iliac artery
0.697 0.303 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.697 0.303 0.000
R53 Malaise and fatigue
0.696 0.304 0.000
F60.3 Emotionally unstable personality disorder
0.695 0.305 0.000
J94 Other pleural conditions
0.695 0.305 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.694 0.306 0.000
T75 Effects of other external causes
0.694 0.306 0.000
T74 Maltreatment syndromes
0.694 0.306 0.000
T73 Effects of other deprivation
0.694 0.306 0.000
T70 Effects of air pressure and water pressure
0.694 0.306 0.000
T69 Other effects of reduced temperature
0.694 0.306 0.000
T67 Effects of heat and light
0.694 0.306 0.000
T71 Asphyxiation
0.694 0.306 0.000
T68 Hypothermia
0.694 0.306 0.000
T66 Unspecified effects of radiation
0.694 0.306 0.000
E24 Cushing's syndrome
0.693 0.307 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.307 0.000
Q64 Other congenital malformations of urinary system
0.692 0.308 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.692 0.308 0.000
H81.8 Other disorders of vestibular function
0.692 0.308 0.000
H81.4 Vertigo of central origin
0.692 0.308 0.000
H81.3 Other peripheral vertigo
0.692 0.308 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.692 0.308 0.000
C85.0 Lymphosarcoma
0.692 0.308 0.000
S06 Intracranial injury
0.691 0.309 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.690 0.310 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.690 0.310 0.000
J93.0 Spontaneous tension pneumothorax
0.689 0.310 0.000
T91.1 Sequelae of fracture of spine
0.688 0.312 0.000
F60.9 Personality disorder, unspecified
0.688 0.312 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
C16.8 Overlapping lesion of stomach
0.686 0.314 0.000
C16.6 Greater curvature of stomach, unspecified
0.686 0.314 0.000
C16.5 Lesser curvature of stomach, unspecified
0.686 0.314 0.000
C16.4 Pylorus
0.686 0.314 0.000
C16.3 Pyloric antrum
0.686 0.314 0.000
C16.2 Body of stomach
0.686 0.314 0.000
C16.1 Fundus of stomach
0.686 0.314 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.686 0.314 0.000
S01.9 Open wound of head, part unspecified
0.686 0.314 0.000
E06.3 Autoimmune thyroiditis
0.686 0.314 0.000
T95 Sequelae of burns, corrosions and frostbite
0.685 0.315 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.685 0.315 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.685 0.315 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.685 0.315 0.000
R25.0 Abnormal head movements
0.685 0.315 0.000
Q63 Other congenital malformations of kidney
0.684 0.316 0.000
E26 Hyperaldosteronism
0.683 0.316 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.683 0.317 0.000
D37.5 Rectum
0.683 0.317 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.683 0.317 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.683 0.317 0.000
R52.1 Chronic intractable pain
0.682 0.317 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.682 0.318 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.682 0.318 0.000
F48 Other neurotic disorders
0.682 0.318 0.000
V40-V49 Car occupant injured in transport accident
0.682 0.318 0.000
T65 Toxic effect of other and unspecified substances
0.681 0.319 0.000
T62 Toxic effect of other noxious substances eaten as food
0.681 0.319 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.681 0.319 0.000
T60 Toxic effect of pesticides
0.681 0.319 0.000
T57 Toxic effect of other inorganic substances
0.681 0.319 0.000
T54 Toxic effect of corrosive substances
0.681 0.319 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.681 0.319 0.000
T52 Toxic effect of organic solvents
0.681 0.319 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.681 0.319 0.000
T58 Toxic effect of carbon monoxide
0.681 0.319 0.000
T55 Toxic effect of soaps and detergents
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.680 0.319 0.000
S07 Crushing injury of head
0.680 0.319 0.000
S04 Injury of cranial nerves
0.680 0.319 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.319 0.000
R57.9 Shock, unspecified
0.680 0.320 0.000
F44.4 Dissociative motor disorders
0.679 0.321 0.000
T78.9 Adverse effect, unspecified
0.677 0.323 0.000
T78.8 Other adverse effects, not elsewhere classified
0.677 0.323 0.000
T43.2 Other and unspecified antidepressants
0.676 0.324 0.000
Q61.9 Cystic kidney disease, unspecified
0.676 0.324 0.000
Q61.8 Other cystic kidney diseases
0.676 0.324 0.000
Q61.5 Medullary cystic kidney
0.676 0.324 0.000
Q61.4 Renal dysplasia
0.676 0.324 0.000
Q61.1 Polycystic kidney, infantile type
0.676 0.324 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.676 0.324 0.000
C80 Malignant neoplasm without specification of site
0.676 0.324 0.000
E22 Hyperfunction of pituitary gland
0.675 0.325 0.000
R90.0 Intracranial space-occupying lesion
0.674 0.326 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.674 0.326 0.000
T39.0 Salicylates
0.672 0.328 0.000
J18 Pneumonia, organism unspecified
0.671 0.329 0.000
C81 Hodgkin's disease
0.671 0.329 0.000
I78.1 Naevus, nonneoplastic
0.670 0.330 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.669 0.331 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.669 0.331 0.000
I72.2 Aneurysm of renal artery
0.669 0.331 0.000
I72.1 Aneurysm of artery of upper extremity
0.669 0.331 0.000
I72.0 Aneurysm of carotid artery
0.669 0.331 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
F80-F89 Disorders of psychological development
0.668 0.332 0.000
T40.4 Other synthetic narcotics
0.667 0.332 0.000
C09 Malignant neoplasm of tonsil
0.664 0.336 0.000
S90-S99 Injuries to the ankle and foot
0.664 0.336 0.000
I73 Other peripheral vascular diseases
0.663 0.337 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.662 0.338 0.000
Y84.2 Radiological procedure and radiotherapy
0.662 0.338 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.661 0.338 0.000
T31 Burns classified according to extent of body surface involved
0.661 0.339 0.000
D43.2 Brain, unspecified
0.661 0.339 0.000
S00.7 Multiple superficial injuries of head
0.661 0.339 0.000
J43 Emphysema
0.661 0.339 0.000
E34.0 Carcinoid syndrome
0.660 0.340 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.660 0.340 0.000
H83 Other diseases of inner ear
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.660 0.340 0.000
Q45 Other congenital malformations of digestive system
0.659 0.341 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.659 0.341 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.659 0.341 0.000
Q40 Other congenital malformations of upper alimentary tract
0.659 0.341 0.000
Q39 Congenital malformations of oesophagus
0.659 0.341 0.000
R61 Hyperhidrosis
0.659 0.341 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.659 0.341 0.000
O80-O84 Delivery
0.659 0.341 0.000
C17.8 Overlapping lesion of small intestine
0.659 0.341 0.000
C17.3 Meckel's diverticulum
0.659 0.341 0.000
C17.1 Jejunum
0.659 0.341 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.658 0.342 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.658 0.342 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.658 0.342 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.657 0.343 0.000
E04 Other non-toxic goitre
0.656 0.344 0.000
Q61.0 Congenital single renal cyst
0.656 0.344 0.000
Q54 Hypospadias
0.656 0.344 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.655 0.344 0.000
T40.8 Lysergide [LSD]
0.655 0.344 0.000
T40.7 Cannabis (derivatives)
0.655 0.344 0.000
T40.5 Cocaine
0.655 0.344 0.000
T40.3 Methadone
0.655 0.344 0.000
T40.1 Heroin
0.655 0.344 0.000
T40.0 Opium
0.655 0.344 0.000
Y84.8 Other medical procedures
0.655 0.345 0.000
C77.5 Intrapelvic lymph nodes
0.655 0.345 0.000
R27 Other lack of coordination
0.655 0.345 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.655 0.345 0.000
F43.1 Posttraumatic stress disorder
0.655 0.345 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.654 0.346 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.653 0.347 0.000
S09.8 Other specified injuries of head
0.652 0.348 0.000
S09.7 Multiple injuries of head
0.652 0.348 0.000
S09.2 Traumatic rupture of ear drum
0.652 0.348 0.000
S09.1 Injury of muscle and tendon of head
0.652 0.348 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.652 0.348 0.000
R68.3 Clubbing of fingers
0.652 0.348 0.000
R68.2 Dry mouth, unspecified
0.652 0.348 0.000
R68.1 Nonspecific symptoms peculiar to infancy
0.652 0.348 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.651 0.349 0.000
D09 Carcinoma in situ of other and unspecified sites
0.651 0.349 0.000
W50-W64 Exposure to animate mechanical forces
0.650 0.350 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.650 0.350 0.000
R69 Unknown and unspecified causes of morbidity
0.649 0.351 0.000
Y84.6 Urinary catheterisation
0.649 0.351 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.648 0.351 0.000
X10-X19 Contact with heat and hot substances
0.648 0.352 0.000
Q43.0 Meckel's diverticulum
0.648 0.352 0.000
R56.8 Other and unspecified convulsions
0.648 0.352 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.648 0.352 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.647 0.353 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.647 0.353 0.000
T45.5 Anticoagulants
0.645 0.355 0.000
C07 Malignant neoplasm of parotid gland
0.645 0.355 0.000
S19 Other and unspecified injuries of neck
0.645 0.355 0.000
I77.8 Other specified disorders of arteries and arterioles
0.644 0.356 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.644 0.356 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.642 0.357 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.642 0.357 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.642 0.357 0.000
T93.0 Sequelae of open wound of lower limb
0.642 0.357 0.000
T93.1 Sequelae of fracture of femur
0.642 0.358 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.642 0.358 0.000
I10-I15 Hypertensive diseases
0.642 0.358 0.000
I09 Other rheumatic heart diseases
0.641 0.359 0.000
I06 Rheumatic aortic valve diseases
0.641 0.359 0.000
C78.0 Secondary malignant neoplasm of lung
0.640 0.360 0.000
R81 Glycosuria
0.640 0.360 0.000
R29.4 Clicking hip
0.640 0.360 0.000
R29.3 Abnormal posture
0.640 0.360 0.000
R29.2 Abnormal reflex
0.640 0.360 0.000
R29.1 Meningismus
0.640 0.360 0.000
R29.0 Tetany
0.640 0.360 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.640 0.360 0.000
C21 Malignant neoplasm of anus and anal canal
0.640 0.360 0.000
Y35-Y36 Legal intervention and operations of war
0.639 0.360 0.000
Y10-Y34 Event of undetermined intent
0.639 0.360 0.000
Y00-Y09 Assault
0.639 0.360 0.000
X85-X99 Assault
0.639 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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