TreeWAS – Variant ID: rs116561927

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
H25-H28 Disorders of lens	1.000	0.000
H26 Other cataract	1.000	0.000
H26.9 Cataract, unspecified	0.999	0.001
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.998	0.002
Chapter II Neoplasms	0.997	0.003
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.996	0.004
Chapter XV Pregnancy, childbirth and the puerperium	0.993	0.007
Z30 Contraceptive management	0.992	0.008
Chapter XX External causes of morbidity and mortality	0.990	0.010
J40-J47 Chronic lower respiratory diseases	0.988	0.012
Z30.2 Sterilisation	0.987	0.013
J90-J94 Other diseases of pleura	0.987	0.013
J95-J99 Other diseases of the respiratory system	0.984	0.016
Z95 Presence of cardiac and vascular implants and grafts	0.978	0.022
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.978	0.022
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.978	0.022
Chapter VI Diseases of the nervous system	0.972	0.028
J98 Other respiratory disorders	0.970	0.030
J90 Pleural effusion, not elsewhere classified	0.965	0.035
S70-S79 Injuries to the hip and thigh	0.962	0.038
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.958	0.042
J98.1 Pulmonary collapse	0.954	0.046
H30-H36 Disorders of choroid and retina	0.949	0.051
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.947	0.053
Z88.0 Personal history of allergy to penicillin	0.942	0.058
D37-D48 Neoplasms of uncertain or unknown behaviour	0.941	0.059
Z95.4 Presence of other heart-valve replacement	0.939	0.061
Z93 Artificial opening status	0.938	0.062
Chapter I Certain infectious and parasitic diseases	0.937	0.063
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.933	0.067
M70-M79 Other soft tissue disorders	0.928	0.072
Z34 Supervision of normal pregnancy	0.922	0.078
Z83 Family history of other specific disorders	0.921	0.079
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.919	0.081
S00-S09 Injuries to the head	0.919	0.081
S50-S59 Injuries to the elbow and forearm	0.918	0.082
M75 Shoulder lesions	0.914	0.086
J46 Status asthmaticus	0.913	0.087
S72 Fracture of femur	0.911	0.089
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.911	0.089
R41 Other symptoms and signs involving cognitive functions and awareness	0.910	0.090
J43 Emphysema	0.909	0.091
R41.0 Disorientation, unspecified	0.909	0.091
H26.4 After-cataract	0.906	0.094
C60-C63 Malignant neoplasms of male genital organs	0.905	0.094
J30-J39 Other diseases of upper respiratory tract	0.904	0.096
G90-G99 Other disorders of the nervous system	0.902	0.098
O20-O29 Other maternal disorders predominantly related to pregnancy	0.901	0.099
Z30.1 Insertion of (intra-uterine) contraceptive device	0.899	0.101
Chapter IX Diseases of the circulatory system	0.897	0.103
H35 Other retinal disorders	0.897	0.103
Chapter XXII Codes for special purposes	0.897	0.103
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.897	0.103
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.896	0.104
I30-I52 Other forms of heart disease	0.892	0.108
Z95.5 Presence of coronary angioplasty implant and graft	0.891	0.109
O32 Maternal care for known or suspected malpresentation of foetus	0.890	0.110
Z80 Family history of malignant neoplasm	0.888	0.112
Z00-Z13 Persons encountering health services for examination and investigation	0.885	0.115
M75.0 Adhesive capsulitis of shoulder	0.883	0.117
I35 Nonrheumatic aortic valve disorders	0.883	0.117
T85 Complications of other internal prosthetic devices, implants and grafts	0.883	0.117
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.881	0.119
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.880	0.120
W00-W19 Falls	0.877	0.123
J32 Chronic sinusitis	0.877	0.123
S60-S69 Injuries to the wrist and hand	0.876	0.124
Z93.6 Other artificial openings of urinary tract status	0.875	0.125
J09-J18 Influenza and pneumonia	0.871	0.129
H25 Senile cataract	0.869	0.131
C51-C58 Malignant neoplasms of female genital organs	0.864	0.136
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.864	0.136
C43-C44 Melanoma and other malignant neoplasms of skin	0.862	0.138
S72.0 Fracture of neck of femur	0.860	0.140
A00-A09 Intestinal infectious diseases	0.860	0.140
Z88.1 Personal history of allergy to other antibiotic agents	0.858	0.142
H33 Retinal detachments and breaks	0.855	0.145
M75.4 Impingement syndrome of shoulder	0.855	0.145
J80-J84 Other respiratory diseases principally affecting the interstitium	0.854	0.146
C61 Malignant neoplasm of prostate	0.853	0.147
S06 Intracranial injury	0.852	0.148
J43.9 Emphysema, unspecified	0.852	0.148
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.850	0.150
J42 Unspecified chronic bronchitis	0.849	0.151
O41 Other disorders of amniotic fluid and membranes	0.848	0.152
I35.0 Aortic (valve) stenosis	0.848	0.152
M20-M25 Other joint disorders	0.847	0.153
J60-J70 Lung diseases due to external agents	0.846	0.154
R50-R69 General symptoms and signs	0.845	0.155
I05-I09 Chronic rheumatic heart diseases	0.843	0.157
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.843	0.157
B95-B98 Bacterial, viral and other infectious agents	0.843	0.157
Z94 Transplanted organ and tissue status	0.841	0.159
O26 Maternal care for other conditions predominantly related to pregnancy	0.839	0.161
R50 Fever of unknown origin	0.836	0.164
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.835	0.165
O36 Maternal care for other known or suspected foetal problems	0.835	0.165
Z12 Special screening examination for neoplasms	0.834	0.166
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.829	0.171
C43 Malignant melanoma of skin	0.827	0.173
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.826	0.174
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.825	0.175
S72.00 Fracture of neck of femur (closed)	0.823	0.177
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.822	0.178
H18 Other disorders of cornea	0.822	0.178
Z96 Presence of other functional implants	0.821	0.179
R50.9 Fever, unspecified	0.821	0.179
S90-S99 Injuries to the ankle and foot	0.820	0.180
S52 Fracture of forearm	0.818	0.182
J44 Other chronic obstructive pulmonary disease	0.816	0.184
M65-M68 Disorders of synovium and tendon	0.816	0.184
Y60-Y69 Misadventures to patients during surgical and medical care	0.816	0.184
H43-H45 Disorders of vitreous body and globe	0.816	0.184
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.813	0.187
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.813	0.187
R22.4 Localised swelling, mass and lump, lower limb	0.812	0.188
O00-O08 Pregnancy with abortive outcome	0.811	0.189
O46 Antepartum haemorrhage, not elsewhere classified	0.810	0.190
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.810	0.190
S40-S49 Injuries to the shoulder and upper arm	0.809	0.191
I08 Multiple valve diseases	0.808	0.192
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.808	0.192
M20 Acquired deformities of fingers and toes	0.808	0.192
Z34.9 Supervision of normal pregnancy, unspecified	0.806	0.194
G20-G26 Extrapyramidal and movement disorders	0.804	0.196
Z83.7 Family history of diseases of the digestive system	0.804	0.196
Z34.8 Supervision of other normal pregnancy	0.802	0.198
H27 Other disorders of lens	0.802	0.198
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.801	0.199
J98.4 Other disorders of lung	0.800	0.200
R60 Oedema, not elsewhere classified	0.799	0.201
J32.9 Chronic sinusitis, unspecified	0.798	0.202
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.798	0.202
T66-T78 Other and unspecified effects of external causes	0.797	0.203
O26.8 Other specified pregnancy-related conditions	0.795	0.205
J32.0 Chronic maxillary sinusitis	0.794	0.206
O47 False labour	0.791	0.209
T93 Sequelae of injuries of lower limb	0.791	0.209
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.790	0.210
S01 Open wound of head	0.788	0.212
W50-W64 Exposure to animate mechanical forces	0.786	0.214
I35.1 Aortic (valve) insufficiency	0.785	0.215
Z93.3 Colostomy status	0.784	0.216
Z12.8 Special screening examination for neoplasm of other sites	0.783	0.217
T88 Other complications of surgical and medical care, not elsewhere classified	0.783	0.217
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.783	0.217
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.783	0.217
C43.6 Malignant melanoma of upper limb, including shoulder	0.783	0.217
S71 Open wound of hip and thigh	0.781	0.219
O34 Maternal care for known or suspected abnormality of pelvic organs	0.781	0.219
J94 Other pleural conditions	0.779	0.221
D00-D09 In situ neoplasms	0.778	0.222
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.777	0.223
Z83.3 Family history of diabetes mellitus	0.777	0.223
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.776	0.223
Z96.1 Presence of intraocular lens	0.776	0.224
V80-V89 Other land transport accidents	0.775	0.225
H35.3 Degeneration of macula and posterior pole	0.775	0.225
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.775	0.225
Z02 Examination and encounter for administrative purposes	0.773	0.227
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.773	0.227
O30 Multiple gestation	0.773	0.227
W19 Unspecified fall	0.773	0.227
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.772	0.228
Z95.1 Presence of aortocoronary bypass graft	0.771	0.229
J91 Pleural effusion in conditions classified elsewhere	0.771	0.229
J92 Pleural plaque	0.770	0.230
H33.2 Serous retinal detachment	0.770	0.230
S20-S29 Injuries to the thorax	0.768	0.232
Z80.0 Family history of malignant neoplasm of digestive organs	0.768	0.232
O35 Maternal care for known or suspected foetal abnormality and damage	0.767	0.233
S51 Open wound of forearm	0.767	0.233
Z80.4 Family history of malignant neoplasm of genital organs	0.765	0.235
Z88.3 Personal history of allergy to other anti-infective agents	0.765	0.235
H35.0 Background retinopathy and retinal vascular changes	0.765	0.235
H35.2 Other proliferative retinopathy	0.763	0.237
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.763	0.237
Z84 Family history of other conditions	0.763	0.237
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.762	0.238
G62 Other polyneuropathies	0.758	0.241
Z86 Personal history of certain other diseases	0.758	0.242
G98 Other disorders of nervous system, not elsewhere classified	0.755	0.245
J95 Postprocedural respiratory disorders, not elsewhere classified	0.755	0.245
V20-V29 Motorcycle rider injured in transport accident	0.755	0.245
Z63 Other problems related to primary support group, including family circumstances	0.755	0.245
Z70-Z76 Persons encountering health services in other circumstances	0.755	0.245
C15-C26 Malignant neoplasms of digestive organs	0.754	0.246
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.753	0.247
I35.2 Aortic (valve) stenosis with insufficiency	0.753	0.247
H25.0 Senile incipient cataract	0.751	0.249
J81 Pulmonary oedema	0.751	0.249
O32.1 Maternal care for breech presentation	0.751	0.249
T86 Failure and rejection of transplanted organs and tissues	0.750	0.250
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.749	0.251
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.749	0.251
J15 Bacterial pneumonia, not elsewhere classified	0.749	0.251
C01 Malignant neoplasm of base of tongue	0.748	0.252
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.747	0.253
Z97 Presence of other devices	0.747	0.253
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.747	0.253
C64-C68 Malignant neoplasms of urinary tract	0.747	0.253
S66 Injury of muscle and tendon at wrist and hand level	0.747	0.253
R44 Other symptoms and signs involving general sensations and perceptions	0.745	0.255
G40-G47 Episodic and paroxysmal disorders	0.745	0.255
H53-H54 Visual disturbances and blindness	0.744	0.256
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.743	0.257
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.743	0.257
S79 Other and unspecified injuries of hip and thigh	0.742	0.257
J44.9 Chronic obstructive pulmonary disease, unspecified	0.742	0.258
T79-T79 Certain early complications of trauma	0.742	0.258
G93 Other disorders of brain	0.742	0.258
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.741	0.259
T83.0 Mechanical complication of urinary (indwelling) catheter	0.740	0.260
H25.1 Senile nuclear cataract	0.739	0.261
G35-G37 Demyelinating diseases of the central nervous system	0.739	0.261
J40 Bronchitis, not specified as acute or chronic	0.738	0.262
I50 Heart failure	0.738	0.262
I49 Other cardiac arrhythmias	0.737	0.263
S02 Fracture of skull and facial bones	0.735	0.265
O41.8 Other specified disorders of amniotic fluid and membranes	0.732	0.268
G91 Hydrocephalus	0.731	0.269
M20.4 Other hammer toe(s) (acquired)	0.729	0.271
S06.5 Traumatic subdural haemorrhage	0.728	0.272
S10-S19 Injuries to the neck	0.727	0.273
J69 Pneumonitis due to solids and liquids	0.727	0.273
R60.0 Localised oedema	0.726	0.274
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.726	0.274
W19.4 Street and highway	0.725	0.275
G00-G09 Inflammatory diseases of the central nervous system	0.725	0.275
M65 Synovitis and tenosynovitis	0.724	0.276
T90 Sequelae of injuries of head	0.724	0.276
S06.0 Concussion	0.724	0.276
M75.1 Rotator cuff syndrome	0.724	0.276
J30 Vasomotor and allergic rhinitis	0.724	0.276
T83.3 Mechanical complication of intra-uterine contraceptive device	0.723	0.277
M71 Other bursopathies	0.722	0.278
G70-G73 Diseases of myoneural junction and muscle	0.719	0.280
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.718	0.282
B99-B99 Other infectious diseases	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
H46-H48 Disorders of optic nerve and visual pathways	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.717	0.283
H26.3 Drug-induced cataract	0.717	0.283
H26.2 Complicated cataract	0.717	0.283
H26.1 Traumatic cataract	0.717	0.283
H26.0 Infantile, juvenile and presenile cataract	0.717	0.283
R40 Somnolence, stupor and coma	0.716	0.284
I44 Atrioventricular and left bundle-branch block	0.716	0.284
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.716	0.284
M75.9 Shoulder lesion, unspecified	0.716	0.284
Z81 Family history of mental and behavioural disorders	0.716	0.284
O60-O75 Complications of labour and delivery	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.715	0.285
C40-C41 Malignant neoplasms of bone and articular cartilage	0.715	0.285
S72.1 Pertrochanteric fracture	0.714	0.286
J93 Pneumothorax	0.714	0.286
Z88.4 Personal history of allergy to anaesthetic agent	0.714	0.286
I42 Cardiomyopathy	0.714	0.286
Z38 Liveborn infants according to place of birth	0.714	0.286
Z32 Pregnancy examination and test	0.714	0.286
Z31 Procreative management	0.714	0.286
O36.5 Maternal care for poor foetal growth	0.712	0.288
O85-O92 Complications predominantly related to the puerperium	0.712	0.288
M86-M90 Other osteopathies	0.712	0.288
Z30.9 Contraceptive management, unspecified	0.711	0.288
Z30.8 Other contraceptive management	0.711	0.288
Z30.4 Surveillance of contraceptive drugs	0.711	0.288
Z30.3 Menstrual extraction	0.711	0.288
Z30.0 General counselling and advice on contraception	0.711	0.288
O03 Spontaneous abortion	0.711	0.289
C20 Malignant neoplasm of rectum	0.711	0.289
I08.1 Disorders of both mitral and tricuspid valves	0.711	0.289
C45 Mesothelioma	0.711	0.289
M79 Other soft tissue disorders, not elsewhere classified	0.710	0.290
M24 Other specific joint derangements	0.710	0.290
Y35-Y36 Legal intervention and operations of war	0.709	0.290
Y10-Y34 Event of undetermined intent	0.709	0.290
Y00-Y09 Assault	0.709	0.290
X85-X99 Assault	0.709	0.290
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.290
X50-X57 Overexertion, travel and privation	0.709	0.290
X40-X49 Accidental poisoning by and exposure to noxious substances	0.709	0.290
X30-X39 Exposure to forces of nature	0.709	0.290
X20-X29 Contact with venomous animals and plants	0.709	0.290
X10-X19 Contact with heat and hot substances	0.709	0.290
X00-X09 Exposure to smoke, fire and flames	0.709	0.290
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.709	0.290
W75-W84 Other accidental threats to breathing	0.709	0.290
W65-W74 Accidental drowning and submersion	0.709	0.290
V98-V99 Other and unspecified transport accidents	0.709	0.290
V95-V97 Air and space transport accidents	0.709	0.290
V90-V94 Water transport accidents	0.709	0.290
V70-V79 Bus occupant injured in transport accident	0.709	0.290
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.290
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.290
V40-V49 Car occupant injured in transport accident	0.709	0.290
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.290
V01-V09 Pedestrian injured in transport accident	0.709	0.290
G80-G83 Cerebral palsy and other paralytic syndromes	0.709	0.291
J41 Simple and mucopurulent chronic bronchitis	0.708	0.291
S01.1 Open wound of eyelid and periocular area	0.708	0.292
Z91 Personal history of risk-factors, not elsewhere classified	0.708	0.292
I95-I99 Other and unspecified disorders of the circulatory system	0.707	0.293
C54 Malignant neoplasm of corpus uteri	0.707	0.293
J18 Pneumonia, organism unspecified	0.707	0.293
Z86.1 Personal history of infectious and parasitic diseases	0.707	0.293
H10-H13 Disorders of conjunctiva	0.706	0.293
Z95.2 Presence of prosthetic heart valve	0.706	0.294
O80-O84 Delivery	0.706	0.294
C04 Malignant neoplasm of floor of mouth	0.706	0.294
J99 Respiratory disorders in diseases classified elsewhere	0.706	0.294
J96 Respiratory failure, not elsewhere classified	0.706	0.294
Y41 Other systemic anti-infectives and antiparasitics	0.705	0.295
Z60 Problems related to social environment	0.704	0.296
G25 Other extrapyramidal and movement disorders	0.704	0.296
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.704	0.296
S62 Fracture at wrist and hand level	0.704	0.296
H18.5 Hereditary corneal dystrophies	0.703	0.297
S92 Fracture of foot, except ankle	0.702	0.298
T84.2 Mechanical complication of internal fixation device of other bones	0.701	0.299
T87 Complications peculiar to reattachment and amputation	0.701	0.299
T80 Complications following infusion, transfusion and therapeutic injection	0.701	0.299
O45 Premature separation of placenta [abruptio placentae]	0.701	0.299
O44 Placenta praevia	0.701	0.299
O43 Placental disorders	0.701	0.299
O33 Maternal care for known or suspected disproportion	0.701	0.299
O31 Complications specific to multiple gestation	0.701	0.299
O40 Polyhydramnios	0.701	0.299
I30 Acute pericarditis	0.701	0.299
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.701	0.299
Z89 Acquired absence of limb	0.700	0.299
Z29 Need for other prophylactic measures	0.700	0.300
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.700	0.300
S80-S89 Injuries to the knee and lower leg	0.699	0.301
H52 Disorders of refraction and accommodation	0.698	0.302
J98.0 Diseases of bronchus, not elsewhere classified	0.697	0.303
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.697	0.303
R60.9 Oedema, unspecified	0.697	0.303
J98.9 Respiratory disorder, unspecified	0.696	0.304
J98.8 Other specified respiratory disorders	0.696	0.304
J98.6 Disorders of diaphragm	0.696	0.304
J98.5 Diseases of mediastinum, not elsewhere classified	0.696	0.304
J98.3 Compensatory emphysema	0.696	0.304
J98.2 Interstitial emphysema	0.696	0.304
R22.0 Localised swelling, mass and lump, head	0.696	0.304
Z88.2 Personal history of allergy to sulphonamides	0.695	0.304
Z83.5 Family history of eye and ear disorders	0.695	0.305
A02 Other Salmonella infections	0.694	0.306
H20 Iridocyclitis	0.694	0.306
Z02.8 Other examinations for administrative purposes	0.693	0.307
Z87 Personal history of other diseases and conditions	0.693	0.307
J32.8 Other chronic sinusitis	0.692	0.308
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.692	0.308
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.691	0.309
H16 Keratitis	0.691	0.309
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.690	0.310
Z95.3 Presence of xenogenic heart valve	0.690	0.310
C51 Malignant neoplasm of vulva	0.690	0.310
S78 Traumatic amputation of hip and thigh	0.690	0.310
S77 Crushing injury of hip and thigh	0.690	0.310
S76 Injury of muscle and tendon at hip and thigh level	0.690	0.310
S75 Injury of blood vessels at hip and thigh level	0.690	0.310
S74 Injury of nerves at hip and thigh level	0.690	0.310
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.690	0.310
S70 Superficial injury of hip and thigh	0.690	0.310
Z93.5 Cystostomy status	0.690	0.310
O46.9 Antepartum haemorrhage, unspecified	0.690	0.310
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.690	0.310
I31 Other diseases of pericardium	0.689	0.311
O32.0 Maternal care for unstable lie	0.689	0.311
T15-T19 Effects of foreign body entering through natural orifice	0.688	0.312
Z93.1 Gastrostomy status	0.688	0.312
I50.1 Left ventricular failure	0.688	0.312
B90-B94 Sequelae of infectious and parasitic diseases	0.687	0.313
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.687	0.313
Z88.7 Personal history of allergy to serum and vaccine	0.687	0.313
X60-X84 Intentional self-harm	0.687	0.313
H55-H59 Other disorders of eye and adnexa	0.687	0.313
H33.0 Retinal detachment with retinal break	0.686	0.314
Z94.4 Liver transplant status	0.686	0.314
I36 Nonrheumatic tricuspid valve disorders	0.686	0.314
A30-A49 Other bacterial diseases	0.686	0.314
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.684	0.316
M77 Other enthesopathies	0.683	0.317
Z94.7 Corneal transplant status	0.683	0.317
M20.6 Acquired deformity of toe(s), unspecified	0.683	0.317
D46 Myelodysplastic syndromes	0.681	0.319
T84.1 Mechanical complication of internal fixation device of bones of limb	0.681	0.319
J36 Peritonsillar abscess	0.681	0.319
R50.0 Fever with chills	0.680	0.320
M21 Other acquired deformities of limbs	0.680	0.320
H32 Chorioretinal disorders in diseases classified elsewhere	0.680	0.320
H31 Other disorders of choroid	0.680	0.320
H30 Chorioretinal inflammation	0.680	0.320
A09.9 Gastroenteritis and colitis of unspecified origin	0.680	0.320
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.679	0.321
Z08 Follow-up examination after treatment for malignant neoplasm	0.679	0.321
S52.0 Fracture of upper end of ulna	0.679	0.321
M60-M63 Disorders of muscles	0.679	0.321
M00-M03 Infectious arthropathies	0.679	0.321
A80-A89 Viral infections of the central nervous system	0.678	0.321
C43.9 Malignant melanoma of skin, unspecified	0.678	0.322
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.677	0.323
I51 Complications and ill-defined descriptions of heart disease	0.677	0.323
S64 Injury of nerves at wrist and hand level	0.677	0.323
Z33 Pregnant state, incidental	0.675	0.325
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.675	0.325
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.675	0.325
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.675	0.325
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.675	0.325
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.675	0.325
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.675	0.325
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.675	0.325
R50.8 Other specified fever	0.674	0.326
S72.4 Fracture of lower end of femur	0.674	0.326
H43 Disorders of vitreous body	0.674	0.326
M40-M43 Deforming dorsopathies	0.674	0.326
Z86.7 Personal history of diseases of the circulatory system	0.673	0.327
Z93.0 Tracheostomy status	0.673	0.327
M91-M94 Chondropathies	0.673	0.327
W20-W49 Exposure to inanimate mechanical forces	0.673	0.327
Z93.9 Artificial opening status, unspecified	0.672	0.327
Z93.8 Other artificial opening status	0.672	0.327
Z93.4 Other artificial openings of gastro-intestinal tract status	0.672	0.327
O94-O99 Other obstetric conditions, not elsewhere classified	0.672	0.328
Q20-Q28 Congenital malformations of the circulatory system	0.672	0.328
B85-B89 Pediculosis, acariasis and other infestations	0.672	0.328
B65-B83 Helminthiases	0.672	0.328
B50-B64 Protozoal diseases	0.672	0.328
B20-B24 Human immunodeficiency virus [HIV] disease	0.672	0.328
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.672	0.328
A75-A79 Rickettsioses	0.672	0.328
A70-A74 Other diseases caused by chlamydiae	0.672	0.328
A65-A69 Other spirochaetal diseases	0.672	0.328
A20-A28 Certain zoonotic bacterial diseases	0.672	0.328
A15-A19 Tuberculosis	0.672	0.328
Z80.8 Family history of malignant neoplasm of other organs or systems	0.671	0.329
D45 Polycythaemia vera	0.671	0.329
M20.1 Hallux valgus (acquired)	0.671	0.329
S01.8 Open wound of other parts of head	0.671	0.329
Chapter V Mental and behavioural disorders	0.671	0.329
O24 Diabetes mellitus in pregnancy	0.670	0.330
C67 Malignant neoplasm of bladder	0.670	0.330
V10-V19 Pedal cyclist injured in transport accident	0.670	0.330
M65.9 Synovitis and tenosynovitis, unspecified	0.670	0.330
D41.4 Bladder	0.669	0.330
G99 Other disorders of nervous system in diseases classified elsewhere	0.669	0.331
D37.4 Colon	0.669	0.331
R95-R99 Ill-defined and unknown causes of mortality	0.669	0.331
S42 Fracture of shoulder and upper arm	0.669	0.331
I44.2 Atrioventricular block, complete	0.669	0.331
G62.9 Polyneuropathy, unspecified	0.668	0.332
O36.8 Maternal care for other specified foetal problems	0.668	0.332
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.667	0.333
Z94.0 Kidney transplant status	0.667	0.333
D07 Carcinoma in situ of other and unspecified genital organs	0.667	0.333
Z13 Special screening examination for other diseases and disorders	0.666	0.334
Y86 Sequelae of other accidents	0.666	0.334
J45 Asthma	0.666	0.334
M76 Enthesopathies of lower limb, excluding foot	0.665	0.334
M73 Soft tissue disorders in diseases classified elsewhere	0.665	0.334
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.665	0.335
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.665	0.335
T85.2 Mechanical complication of intraocular lens	0.665	0.335
D37.5 Rectum	0.664	0.335
H33.5 Other retinal detachments	0.663	0.336
Y52 Agents primarily affecting the cardiovascular system	0.662	0.338
I34 Nonrheumatic mitral valve disorders	0.661	0.339
J80 Adult respiratory distress syndrome	0.661	0.339
W07 Fall involving chair	0.661	0.339
Z34.0 Supervision of normal first pregnancy	0.661	0.339
T83.1 Mechanical complication of other urinary devices and implants	0.661	0.339
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.661	0.339
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.661	0.339
A50-A64 Infections with a predominantly sexual mode of transmission	0.660	0.340
Z83.6 Family history of diseases of the respiratory system	0.660	0.340
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.660	0.340
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.660	0.340
Z83.1 Family history of other infectious and parasitic diseases	0.660	0.340
Z83.0 Family history of human immunodeficiency virus [HIV]	0.660	0.340
H27.0 Aphakia	0.660	0.340
I35.9 Aortic valve disorder, unspecified	0.660	0.340
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.659	0.341
R46 Symptoms and signs involving appearance and behaviour	0.659	0.341
R43 Disturbances of smell and taste	0.659	0.341
S08 Traumatic amputation of part of head	0.659	0.341
S07 Crushing injury of head	0.659	0.341
S05 Injury of eye and orbit	0.659	0.341
S04 Injury of cranial nerves	0.659	0.341
S03 Dislocation, sprain and strain of joints and ligaments of head	0.659	0.341

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations