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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116620409
log Bayes Factor = 12.7917
Chromosome 2   position 46,121,281  (GRCh37) Explore rs116620409 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.989 0.011 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.988 0.012 0.000
R41.0 Disorientation, unspecified
0.988 0.012 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.985 0.015 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.985 0.015 0.000
I42 Cardiomyopathy
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
Chapter I Certain infectious and parasitic diseases
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
R42 Dizziness and giddiness
0.973 0.027 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
R00 Abnormalities of heart beat
0.961 0.039 0.000
S80-S89 Injuries to the knee and lower leg
0.949 0.051 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.946 0.054 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.946 0.054 0.000
M50-M54 Other dorsopathies
0.941 0.059 0.000
B95-B98 Bacterial, viral and other infectious agents
0.940 0.060 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.937 0.063 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.935 0.065 0.000
M70-M79 Other soft tissue disorders
0.934 0.066 0.000
R26 Abnormalities of gait and mobility
0.932 0.068 0.000
M65-M68 Disorders of synovium and tendon
0.928 0.072 0.000
R00.0 Tachycardia, unspecified
0.928 0.072 0.000
Chapter VIII Diseases of the ear and mastoid process
0.926 0.074 0.000
E10-E14 Diabetes mellitus
0.926 0.074 0.000
I42.0 Dilated cardiomyopathy
0.924 0.076 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.924 0.076 0.000
Y43 Primarily systemic agents
0.921 0.079 0.000
M54 Dorsalgia
0.917 0.083 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.913 0.087 0.000
I77 Other disorders of arteries and arterioles
0.911 0.089 0.000
S82 Fracture of lower leg, including ankle
0.910 0.090 0.000
E10 Insulin-dependent diabetes mellitus
0.910 0.090 0.000
S00 Superficial injury of head
0.910 0.090 0.000
Chapter XXII Codes for special purposes
0.906 0.094 0.000
F10.1 Harmful use
0.903 0.097 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.902 0.098 0.000
R02 Gangrene, not elsewhere classified
0.901 0.099 0.000
I42.2 Other hypertrophic cardiomyopathy
0.898 0.102 0.000
H65-H75 Diseases of middle ear and mastoid
0.897 0.103 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.895 0.105 0.000
F10.3 Withdrawal state
0.894 0.106 0.000
F10.0 Acute intoxication
0.893 0.107 0.000
R00.2 Palpitations
0.891 0.109 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.884 0.116 0.000
S10-S19 Injuries to the neck
0.883 0.117 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.883 0.117 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.879 0.121 0.000
M72 Fibroblastic disorders
0.879 0.121 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.878 0.122 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.876 0.124 0.000
Y52 Agents primarily affecting the cardiovascular system
0.874 0.126 0.000
I78 Diseases of capillaries
0.871 0.129 0.000
F10.2 Dependence syndrome
0.865 0.135 0.000
E11 Non-insulin-dependent diabetes mellitus
0.862 0.138 0.000
S70-S79 Injuries to the hip and thigh
0.857 0.143 0.000
G30-G32 Other degenerative diseases of the nervous system
0.855 0.145 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.853 0.147 0.000
H65 Nonsuppurative otitis media
0.852 0.148 0.000
S81 Open wound of lower leg
0.851 0.149 0.000
Y43.3 Other antineoplastic drugs
0.849 0.151 0.000
I05-I09 Chronic rheumatic heart diseases
0.846 0.154 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.846 0.154 0.000
S82.3 Fracture of lower end of tibia
0.846 0.154 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.846 0.154 0.000
G90-G99 Other disorders of the nervous system
0.842 0.157 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.842 0.158 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.841 0.159 0.000
M65 Synovitis and tenosynovitis
0.841 0.159 0.000
I31 Other diseases of pericardium
0.840 0.160 0.000
I44 Atrioventricular and left bundle-branch block
0.839 0.161 0.000
Y40 Systemic antibiotics
0.831 0.169 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.830 0.170 0.000
R29.6 Tendency to fall, not elsewhere classified
0.830 0.170 0.000
A00-A09 Intestinal infectious diseases
0.830 0.170 0.000
R06 Abnormalities of breathing
0.826 0.174 0.000
E11.5 With peripheral circulatory complications
0.823 0.177 0.000
M67 Other disorders of synovium and tendon
0.820 0.180 0.000
M54.2 Cervicalgia
0.818 0.182 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.818 0.182 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.818 0.182 0.000
R45 Symptoms and signs involving emotional state
0.817 0.183 0.000
S01 Open wound of head
0.816 0.184 0.000
M54.3 Sciatica
0.816 0.184 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
I34 Nonrheumatic mitral valve disorders
0.814 0.186 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.814 0.186 0.000
R21 Rash and other nonspecific skin eruption
0.813 0.187 0.000
X60-X84 Intentional self-harm
0.812 0.187 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.812 0.188 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.808 0.192 0.000
Chapter X Diseases of the respiratory system
0.803 0.197 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.802 0.198 0.000
R04 Haemorrhage from respiratory passages
0.801 0.199 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.800 0.200 0.000
Y45.0 Opioids and related analgesics
0.798 0.202 0.000
I77.6 Arteritis, unspecified
0.797 0.203 0.000
E10.9 Without complications
0.797 0.203 0.000
F29 Unspecified nonorganic psychosis
0.796 0.204 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.795 0.205 0.000
G70-G73 Diseases of myoneural junction and muscle
0.795 0.205 0.000
I78.1 Naevus, nonneoplastic
0.795 0.205 0.000
F10.4 Withdrawal state with delirium
0.794 0.205 0.000
I05 Rheumatic mitral valve diseases
0.792 0.208 0.000
H65.3 Chronic mucoid otitis media
0.792 0.208 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.788 0.212 0.000
I10-I15 Hypertensive diseases
0.786 0.214 0.000
F20 Schizophrenia
0.785 0.215 0.000
I74 Arterial embolism and thrombosis
0.782 0.218 0.000
V40-V49 Car occupant injured in transport accident
0.780 0.220 0.000
F30-F39 Mood [affective] disorders
0.780 0.220 0.000
R06.0 Dyspnoea
0.778 0.222 0.000
J20-J22 Other acute lower respiratory infections
0.777 0.223 0.000
F11 Mental and behavioural disorders due to use of opioids
0.777 0.223 0.000
S05 Injury of eye and orbit
0.777 0.223 0.000
I38 Endocarditis, valve unspecified
0.777 0.223 0.000
I37 Pulmonary valve disorders
0.775 0.225 0.000
S82.30 Fracture of lower end of tibia (closed)
0.775 0.225 0.000
S00.9 Superficial injury of head, part unspecified
0.775 0.225 0.000
I45 Other conduction disorders
0.773 0.227 0.000
M60-M63 Disorders of muscles
0.770 0.230 0.000
M77 Other enthesopathies
0.768 0.232 0.000
R20 Disturbances of skin sensation
0.768 0.232 0.000
Y48 Anaesthetics and therapeutic gases
0.766 0.234 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.765 0.235 0.000
E10.5 With peripheral circulatory complications
0.764 0.236 0.000
G62 Other polyneuropathies
0.764 0.236 0.000
S10 Superficial injury of neck
0.763 0.237 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.763 0.237 0.000
Y57 Other and unspecified drugs and medicaments
0.763 0.237 0.000
R25 Abnormal involuntary movements
0.762 0.237 0.000
H74 Other disorders of middle ear and mastoid
0.762 0.238 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.761 0.239 0.000
J22 Unspecified acute lower respiratory infection
0.761 0.239 0.000
I77.8 Other specified disorders of arteries and arterioles
0.760 0.240 0.000
S72 Fracture of femur
0.759 0.241 0.000
S06 Intracranial injury
0.759 0.241 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.757 0.243 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.757 0.243 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.757 0.243 0.000
S81.8 Open wound of other parts of lower leg
0.757 0.243 0.000
D70 Agranulocytosis
0.756 0.244 0.000
Y52.1 Calcium-channel blockers
0.756 0.244 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.756 0.244 0.000
U80 Agent resistant to penicillin and related antibiotics
0.755 0.245 0.000
G93 Other disorders of brain
0.754 0.246 0.000
M54.5 Low back pain
0.754 0.246 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.754 0.246 0.000
D80-D89 Certain disorders involving the immune mechanism
0.754 0.246 0.000
Y45.8 Other analgesics and antipyretics
0.752 0.248 0.000
I72 Other aneurysm
0.752 0.248 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.750 0.250 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.748 0.251 0.000
E10.4 With neurological complications
0.748 0.252 0.000
W20-W49 Exposure to inanimate mechanical forces
0.747 0.252 0.000
T66-T78 Other and unspecified effects of external causes
0.747 0.253 0.000
I70 Atherosclerosis
0.746 0.254 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.743 0.257 0.000
G63.2 Diabetic polyneuropathy
0.743 0.257 0.000
I51 Complications and ill-defined descriptions of heart disease
0.742 0.258 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.742 0.258 0.000
H66 Suppurative and unspecified otitis media
0.741 0.259 0.000
I34.1 Mitral (valve) prolapse
0.741 0.259 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.741 0.259 0.000
I47 Paroxysmal tachycardia
0.741 0.259 0.000
R06.4 Hyperventilation
0.740 0.260 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.738 0.262 0.000
S20-S29 Injuries to the thorax
0.738 0.262 0.000
E10.8 With unspecified complications
0.738 0.262 0.000
R41.3 Other amnesia
0.738 0.262 0.000
F99-F99 Unspecified mental disorder
0.738 0.262 0.000
S02 Fracture of skull and facial bones
0.737 0.263 0.000
M80-M85 Disorders of bone density and structure
0.737 0.263 0.000
F25 Schizoaffective disorders
0.737 0.263 0.000
S82.2 Fracture of shaft of tibia
0.736 0.264 0.000
E10.3 With ophthalmic complications
0.736 0.264 0.000
I31.9 Disease of pericardium, unspecified
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.735 0.264 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.735 0.265 0.000
Y43.4 Immunosuppressive agents
0.735 0.265 0.000
M54.1 Radiculopathy
0.734 0.266 0.000
M91-M94 Chondropathies
0.733 0.266 0.000
F80-F89 Disorders of psychological development
0.733 0.267 0.000
D69 Purpura and other haemorrhagic conditions
0.733 0.267 0.000
I77.1 Stricture of artery
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
E10.2 With renal complications
0.733 0.267 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.731 0.269 0.000
D72 Other disorders of white blood cells
0.730 0.270 0.000
S00.0 Superficial injury of scalp
0.729 0.271 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.729 0.271 0.000
I73 Other peripheral vascular diseases
0.727 0.273 0.000
Y60.0 During surgical operation
0.726 0.274 0.000
A30-A49 Other bacterial diseases
0.725 0.275 0.000
D55-D59 Haemolytic anaemias
0.725 0.275 0.000
I30 Acute pericarditis
0.724 0.276 0.000
M67.8 Other specified disorders of synovium and tendon
0.724 0.276 0.000
S01.0 Open wound of scalp
0.724 0.276 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.723 0.277 0.000
G20-G26 Extrapyramidal and movement disorders
0.722 0.278 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.722 0.278 0.000
S00.1 Contusion of eyelid and periocular area
0.722 0.278 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.721 0.279 0.000
R23 Other skin changes
0.721 0.279 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.720 0.280 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.720 0.280 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.719 0.281 0.000
I12 Hypertensive renal disease
0.719 0.281 0.000
S50-S59 Injuries to the elbow and forearm
0.718 0.282 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R46 Symptoms and signs involving appearance and behaviour
0.717 0.283 0.000
R43 Disturbances of smell and taste
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M54.29 Cervicalgia-Site unspe
0.716 0.284 0.000
S81.0 Open wound of knee
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
A08 Viral and other specified intestinal infections
0.714 0.286 0.000
R05 Cough
0.714 0.286 0.000
R41.2 Retrograde amnesia
0.714 0.286 0.000
R41.1 Anterograde amnesia
0.714 0.286 0.000
W00-W19 Falls
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
Y42.7 Androgens and anabolic congeners
0.713 0.287 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.288 0.000
Y58 Bacterial vaccines
0.711 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.711 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.288 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.288 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.288 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.711 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.289 0.000
S82.4 Fracture of fibula alone
0.710 0.290 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.710 0.290 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.290 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.709 0.291 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.709 0.291 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.709 0.291 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.709 0.291 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.709 0.291 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.709 0.291 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.709 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.709 0.291 0.000
S82.5 Fracture of medial malleolus
0.709 0.291 0.000
D60-D64 Aplastic and other anaemias
0.708 0.292 0.000
G61 Inflammatory polyneuropathy
0.707 0.293 0.000
F10.9 Unspecified mental and behavioural disorder
0.706 0.293 0.000
F10.8 Other mental and behavioural disorders
0.706 0.293 0.000
F10.7 Residual and late-onset psychotic disorder
0.706 0.293 0.000
F10.6 Amnesic syndrome
0.706 0.293 0.000
F10.5 Psychotic disorder
0.706 0.293 0.000
I46 Cardiac arrest
0.706 0.294 0.000
I42.8 Other cardiomyopathies
0.706 0.294 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.706 0.294 0.000
I42.6 Alcoholic cardiomyopathy
0.706 0.294 0.000
I42.5 Other restrictive cardiomyopathy
0.706 0.294 0.000
I42.4 Endocardial fibroelastosis
0.706 0.294 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.706 0.294 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.706 0.294 0.000
I05.9 Mitral valve disease, unspecified
0.705 0.295 0.000
J60-J70 Lung diseases due to external agents
0.705 0.295 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.705 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
S19 Other and unspecified injuries of neck
0.701 0.298 0.000
I44.0 Atrioventricular block, first degree
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
R27 Other lack of coordination
0.700 0.300 0.000
M54.36 Sciatica (Lumbar region)
0.699 0.301 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.698 0.302 0.000
M54.6 Pain in thoracic spine
0.698 0.302 0.000
J09-J18 Influenza and pneumonia
0.698 0.302 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
I42.9 Cardiomyopathy, unspecified
0.692 0.308 0.000
E11.4 With neurological complications
0.692 0.308 0.000
H72 Perforation of tympanic membrane
0.691 0.309 0.000
S82.31 Fracture of lower end of tibia (open)
0.691 0.309 0.000
R04.0 Epistaxis
0.690 0.309 0.000
S82.1 Fracture of upper end of tibia
0.690 0.310 0.000
F23 Acute and transient psychotic disorders
0.689 0.311 0.000
S00.3 Superficial injury of nose
0.688 0.312 0.000
R20.2 Paraesthesia of skin
0.686 0.314 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.686 0.314 0.000
H65.2 Chronic serous otitis media
0.685 0.315 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.685 0.315 0.000
M71 Other bursopathies
0.685 0.315 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.683 0.317 0.000
M65.8 Other synovitis and tenosynovitis
0.682 0.318 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.681 0.319 0.000
S82.6 Fracture of lateral malleolus
0.681 0.319 0.000
S88 Traumatic amputation of lower leg
0.680 0.319 0.000
S87 Crushing injury of lower leg
0.680 0.319 0.000
S86 Injury of muscle and tendon at lower leg level
0.680 0.319 0.000
S85 Injury of blood vessels at lower leg level
0.680 0.319 0.000
S84 Injury of nerves at lower leg level
0.680 0.319 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.680 0.320 0.000
M51 Other intervertebral disk disorders
0.680 0.320 0.000
S01.7 Multiple open wounds of head
0.680 0.320 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.679 0.320 0.000
V10-V19 Pedal cyclist injured in transport accident
0.679 0.321 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.679 0.321 0.000
H80-H83 Diseases of inner ear
0.678 0.322 0.000
R01 Cardiac murmurs and other cardiac sounds
0.678 0.322 0.000
S10.9 Superficial injury of neck, part unspecified
0.677 0.322 0.000
M72.2 Plantar fascial fibromatosis
0.677 0.323 0.000
R07 Pain in throat and chest
0.677 0.323 0.000
M54.9 Dorsalgia, unspecified
0.677 0.323 0.000
M53 Other dorsopathies, not elsewhere classified
0.675 0.325 0.000
Y40.0 Penicillins
0.674 0.326 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
R29.4 Clicking hip
0.672 0.328 0.000
R29.3 Abnormal posture
0.672 0.328 0.000
R29.2 Abnormal reflex
0.672 0.328 0.000
R29.1 Meningismus
0.672 0.328 0.000
R29.0 Tetany
0.672 0.328 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
I12.9 Hypertensive renal disease without renal failure
0.671 0.329 0.000
Y95 Nosocomial condition
0.671 0.329 0.000
B15-B19 Viral hepatitis
0.670 0.330 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.670 0.330 0.000
S90-S99 Injuries to the ankle and foot
0.670 0.330 0.000
M76 Enthesopathies of lower limb, excluding foot
0.669 0.331 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.669 0.331 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.668 0.332 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.668 0.332 0.000
R26.1 Paralytic gait
0.668 0.332 0.000
R26.0 Ataxic gait
0.668 0.332 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.668 0.332 0.000
B35-B49 Mycoses
0.666 0.334 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.666 0.334 0.000
M66 Spontaneous rupture of synovium and tendon
0.666 0.334 0.000
E10.1 With ketoacidosis
0.665 0.335 0.000
E20-E35 Disorders of other endocrine glands
0.664 0.336 0.000
E12 Malnutrition-related diabetes mellitus
0.664 0.336 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.663 0.337 0.000
F28 Other nonorganic psychotic disorders
0.662 0.338 0.000
F24 Induced delusional disorder
0.662 0.338 0.000
F21 Schizotypal disorder
0.662 0.338 0.000
G62.8 Other specified polyneuropathies
0.662 0.338 0.000
Y43.9 Primarily systemic agent, unspecified
0.660 0.340 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.660 0.340 0.000
Y43.6 Enzymes, not elsewhere classified
0.660 0.340 0.000
Y43.5 Acidifying and alkalising agents
0.660 0.340 0.000
Y43.2 Antineoplastic natural products
0.660 0.340 0.000
Y43.1 Antineoplastic antimetabolites
0.660 0.340 0.000
Y43.0 Antiallergic and antiemetic drugs
0.660 0.340 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.660 0.340 0.000
I44.7 Left bundle-branch block, unspecified
0.660 0.340 0.000
M54.22 Cervicalgia (Cervical region)
0.659 0.341 0.000
S12 Fracture of neck
0.657 0.343 0.000
M54.8 Other dorsalgia
0.657 0.343 0.000
M54.0 Panniculitis affecting regions of neck and back
0.657 0.343 0.000
G30 Alzheimer's disease
0.657 0.343 0.000
S01.1 Open wound of eyelid and periocular area
0.656 0.344 0.000
I99 Other and unspecified disorders of circulatory system
0.655 0.345 0.000
M54.39 Sciatica (Site unspecified)
0.655 0.345 0.000
G60 Hereditary and idiopathic neuropathy
0.655 0.345 0.000
G64 Other disorders of peripheral nervous system
0.655 0.345 0.000
I44.6 Other and unspecified fascicular block
0.655 0.345 0.000
E11.3 With ophthalmic complications
0.653 0.347 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.653 0.347 0.000
I77.5 Necrosis of artery
0.653 0.347 0.000
I77.4 Coeliac artery compression syndrome
0.653 0.347 0.000
I77.3 Arterial fibromuscular dysplasia
0.653 0.347 0.000
I77.2 Rupture of artery
0.653 0.347 0.000
I77.0 Arteriovenous fistula, acquired
0.653 0.347 0.000
G81 Hemiplegia
0.653 0.347 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.653 0.347 0.000
S82.9 Fracture of lower leg, part unspecified
0.653 0.347 0.000
S82.7 Multiple fractures of lower leg
0.653 0.347 0.000
H65.4 Other chronic nonsuppurative otitis media
0.653 0.347 0.000
E10.7 With multiple complications
0.652 0.348 0.000
E10.6 With other specified complications
0.652 0.348 0.000
E10.0 With coma
0.652 0.348 0.000
S00.7 Multiple superficial injuries of head
0.652 0.348 0.000
S00.5 Superficial injury of lip and oral cavity
0.652 0.348 0.000
S00.4 Superficial injury of ear
0.652 0.348 0.000
S71 Open wound of hip and thigh
0.652 0.348 0.000
S72.1 Pertrochanteric fracture
0.650 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.649 0.351 0.000
M89 Other disorders of bone
0.648 0.352 0.000
R45.1 Restlessness and agitation
0.648 0.352 0.000
E40-E46 Malnutrition
0.647 0.353 0.000
D69.6 Thrombocytopenia, unspecified
0.647 0.353 0.000
I05.0 Mitral stenosis
0.647 0.353 0.000
G90 Disorders of autonomic nervous system
0.646 0.354 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.645 0.355 0.000
H60-H62 Diseases of external ear
0.644 0.355 0.000
J69 Pneumonitis due to solids and liquids
0.644 0.356 0.000
R45.2 Unhappiness
0.643 0.357 0.000
S82.8 Fractures of other parts of lower leg
0.643 0.357 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.643 0.357 0.000
H70 Mastoiditis and related conditions
0.643 0.357 0.000
H69 Other disorders of Eustachian tube
0.643 0.357 0.000
H68 Eustachian salpingitis and obstruction
0.643 0.357 0.000
H67 Otitis media in diseases classified elsewhere
0.643 0.357 0.000
M90 Osteopathies in diseases classified elsewhere
0.643 0.357 0.000
M40-M43 Deforming dorsopathies
0.642 0.357 0.000
M54.56 Low back pain (Lumbar region)
0.642 0.358 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.642 0.358 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.642 0.358 0.000
D72.8 Other specified disorders of white blood cells
0.641 0.358 0.000
S05.8 Other injuries of eye and orbit
0.641 0.359 0.000
S00.8 Superficial injury of other parts of head
0.641 0.359 0.000
F30 Manic episode
0.640 0.359 0.000
E13 Other specified diabetes mellitus
0.640 0.360 0.000
M50 Cervical disk disorders
0.640 0.360 0.000
G70 Myasthenia gravis and other myoneural disorders
0.639 0.361 0.000
U80.0 Penicillin resistant agent
0.639 0.361 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.639 0.361 0.000
S40-S49 Injuries to the shoulder and upper arm
0.638 0.362 0.000
F20.0 Paranoid schizophrenia
0.638 0.362 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.638 0.362 0.000
M70.6 Trochanteric bursitis
0.638 0.362 0.000
I05.2 Mitral stenosis with insufficiency
0.638 0.362 0.000
S80 Superficial injury of lower leg
0.637 0.363 0.000
Q60-Q64 Congenital malformations of the urinary system
0.637 0.363 0.000
F20.9 Schizophrenia, unspecified
0.636 0.364 0.000
E11.2 With renal complications
0.636 0.364 0.000
I73.9 Peripheral vascular disease, unspecified
0.636 0.364 0.000
M87 Osteonecrosis
0.635 0.364 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.635 0.365 0.000
F33 Recurrent depressive disorder
0.634 0.365 0.000
H74.4 Polyp of middle ear
0.634 0.366 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.634 0.366 0.000
Y45.5 4-Aminophenol derivatives
0.634 0.366 0.000
Y45.4 Antirheumatics
0.634 0.366 0.000
Y45.2 Propionic acid derivatives
0.634 0.366 0.000
V20-V29 Motorcycle rider injured in transport accident
0.633 0.366 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.633 0.366 0.000
S17 Crushing injury of neck
0.633 0.367 0.000
S15 Injury of blood vessels at neck level
0.633 0.367 0.000
S14 Injury of nerves and spinal cord at neck level
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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