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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116927146
log Bayes Factor = 15.0921
Chromosome 3   position 152,264,287  (GRCh37) Explore rs116927146 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
D00-D09 In situ neoplasms
0.993 0.007 0.000
I20 Angina pectoris
0.988 0.012 0.000
I60-I69 Cerebrovascular diseases
0.986 0.014 0.000
H35 Other retinal disorders
0.983 0.017 0.000
D05 Carcinoma in situ of breast
0.983 0.017 0.000
I20.9 Angina pectoris, unspecified
0.976 0.024 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.975 0.025 0.000
S60-S69 Injuries to the wrist and hand
0.970 0.030 0.000
I21 Acute myocardial infarction
0.963 0.037 0.000
Chapter XIV Diseases of the genitourinary system
0.962 0.038 0.000
I42 Cardiomyopathy
0.959 0.041 0.000
I25 Chronic ischaemic heart disease
0.953 0.047 0.000
I67 Other cerebrovascular diseases
0.951 0.049 0.000
Chapter VI Diseases of the nervous system
0.949 0.051 0.000
D05.1 Intraductal carcinoma in situ
0.948 0.052 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
F30-F39 Mood [affective] disorders
0.943 0.057 0.000
H35.8 Other specified retinal disorders
0.940 0.060 0.000
D10-D36 Benign neoplasms
0.938 0.062 0.000
I21.9 Acute myocardial infarction, unspecified
0.934 0.066 0.000
Chapter XX External causes of morbidity and mortality
0.932 0.068 0.000
F20 Schizophrenia
0.923 0.077 0.000
H33 Retinal detachments and breaks
0.913 0.087 0.000
G90-G99 Other disorders of the nervous system
0.913 0.087 0.000
H34 Retinal vascular occlusions
0.905 0.095 0.000
Chapter X Diseases of the respiratory system
0.905 0.095 0.000
N60-N64 Disorders of breast
0.904 0.096 0.000
D24 Benign neoplasm of breast
0.901 0.099 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.900 0.100 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.889 0.111 0.000
I67.9 Cerebrovascular disease, unspecified
0.889 0.111 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.887 0.113 0.000
I20.8 Other forms of angina pectoris
0.887 0.113 0.000
H55-H59 Other disorders of eye and adnexa
0.885 0.115 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.881 0.119 0.000
I25.2 Old myocardial infarction
0.880 0.120 0.000
H36 Retinal disorders in diseases classified elsewhere
0.880 0.120 0.000
I42.0 Dilated cardiomyopathy
0.879 0.121 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.879 0.121 0.000
I44 Atrioventricular and left bundle-branch block
0.877 0.123 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.877 0.123 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.876 0.124 0.000
F22 Persistent delusional disorders
0.869 0.131 0.000
F20.9 Schizophrenia, unspecified
0.867 0.133 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.864 0.135 0.000
F32 Depressive episode
0.864 0.136 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.864 0.136 0.000
N17-N19 Renal failure
0.864 0.136 0.000
S60 Superficial injury of wrist and hand
0.862 0.138 0.000
D22 Melanocytic naevi
0.856 0.144 0.000
H35.4 Peripheral retinal degeneration
0.856 0.144 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.855 0.145 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.853 0.147 0.000
I42.9 Cardiomyopathy, unspecified
0.853 0.147 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.850 0.150 0.000
I50 Heart failure
0.850 0.150 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.849 0.151 0.000
S50-S59 Injuries to the elbow and forearm
0.848 0.152 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.847 0.153 0.000
Chapter I Certain infectious and parasitic diseases
0.844 0.156 0.000
J40-J47 Chronic lower respiratory diseases
0.843 0.157 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.842 0.157 0.000
D25 Leiomyoma of uterus
0.840 0.160 0.000
I67.8 Other specified cerebrovascular diseases
0.839 0.161 0.000
S40-S49 Injuries to the shoulder and upper arm
0.837 0.163 0.000
F33 Recurrent depressive disorder
0.837 0.163 0.000
I63 Cerebral infarction
0.836 0.163 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.836 0.164 0.000
D18 Haemangioma and lymphangioma, any site
0.836 0.164 0.000
I22 Subsequent myocardial infarction
0.830 0.170 0.000
H34.8 Other retinal vascular occlusions
0.830 0.170 0.000
H43-H45 Disorders of vitreous body and globe
0.829 0.171 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.828 0.172 0.000
H40-H42 Glaucoma
0.826 0.174 0.000
I34 Nonrheumatic mitral valve disorders
0.826 0.174 0.000
N73 Other female pelvic inflammatory diseases
0.825 0.175 0.000
N19 Unspecified renal failure
0.824 0.176 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.824 0.176 0.000
D05.0 Lobular carcinoma in situ
0.823 0.177 0.000
I35 Nonrheumatic aortic valve disorders
0.823 0.177 0.000
I05-I09 Chronic rheumatic heart diseases
0.822 0.177 0.000
D09 Carcinoma in situ of other and unspecified sites
0.822 0.178 0.000
I33 Acute and subacute endocarditis
0.820 0.180 0.000
S61 Open wound of wrist and hand
0.820 0.180 0.000
D69 Purpura and other haemorrhagic conditions
0.819 0.181 0.000
N63 Unspecified lump in breast
0.818 0.182 0.000
S00-S09 Injuries to the head
0.817 0.183 0.000
D70 Agranulocytosis
0.817 0.183 0.000
N60 Benign mammary dysplasia
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.808 0.191 0.000
H35.0 Background retinopathy and retinal vascular changes
0.807 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.805 0.195 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.803 0.197 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.800 0.200 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.799 0.201 0.000
H35.6 Retinal haemorrhage
0.799 0.201 0.000
C50-C50 Malignant neoplasm of breast
0.799 0.201 0.000
H33.3 Retinal breaks without detachment
0.798 0.202 0.000
H36.0 Diabetic retinopathy
0.795 0.205 0.000
F22.0 Delusional disorder
0.794 0.206 0.000
Chapter XXII Codes for special purposes
0.794 0.206 0.000
I45 Other conduction disorders
0.793 0.207 0.000
I62 Other nontraumatic intracranial haemorrhage
0.791 0.209 0.000
I51 Complications and ill-defined descriptions of heart disease
0.791 0.209 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
D25.9 Leiomyoma of uterus, unspecified
0.790 0.210 0.000
N73.6 Female pelvic peritoneal adhesions
0.786 0.214 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.786 0.214 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.785 0.215 0.000
E10-E14 Diabetes mellitus
0.784 0.216 0.000
N10-N16 Renal tubulo-interstitial diseases
0.783 0.217 0.000
I73 Other peripheral vascular diseases
0.782 0.218 0.000
F80-F89 Disorders of psychological development
0.779 0.221 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.778 0.222 0.000
D35.2 Pituitary gland
0.774 0.226 0.000
I50.9 Heart failure, unspecified
0.773 0.227 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.773 0.227 0.000
I49 Other cardiac arrhythmias
0.772 0.228 0.000
J44 Other chronic obstructive pulmonary disease
0.772 0.228 0.000
F23 Acute and transient psychotic disorders
0.771 0.229 0.000
L20-L30 Dermatitis and eczema
0.769 0.231 0.000
I44.1 Atrioventricular block, second degree
0.768 0.232 0.000
T31 Burns classified according to extent of body surface involved
0.768 0.232 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.768 0.232 0.000
S64 Injury of nerves at wrist and hand level
0.767 0.233 0.000
I31 Other diseases of pericardium
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.765 0.235 0.000
Y43 Primarily systemic agents
0.764 0.236 0.000
D26 Other benign neoplasms of uterus
0.764 0.236 0.000
D18.0 Haemangioma, any site
0.763 0.237 0.000
F33.9 Recurrent depressive disorder, unspecified
0.761 0.239 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.761 0.239 0.000
H10-H13 Disorders of conjunctiva
0.761 0.239 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.761 0.239 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.760 0.240 0.000
J40 Bronchitis, not specified as acute or chronic
0.759 0.241 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.759 0.241 0.000
I21.4 Acute subendocardial myocardial infarction
0.758 0.242 0.000
G96 Other disorders of central nervous system
0.758 0.242 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.757 0.243 0.000
N60.4 Mammary duct ectasia
0.755 0.245 0.000
D35.0 Adrenal gland
0.755 0.245 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.755 0.245 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.754 0.246 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.752 0.248 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.751 0.249 0.000
I20.1 Angina pectoris with documented spasm
0.749 0.251 0.000
F20.0 Paranoid schizophrenia
0.747 0.253 0.000
D04 Carcinoma in situ of skin
0.747 0.253 0.000
S09 Other and unspecified injuries of head
0.746 0.254 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.746 0.254 0.000
I67.2 Cerebral atherosclerosis
0.746 0.254 0.000
I73.0 Raynaud's syndrome
0.746 0.254 0.000
S20-S29 Injuries to the thorax
0.745 0.255 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.744 0.256 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.742 0.257 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.741 0.259 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.739 0.261 0.000
H33.0 Retinal detachment with retinal break
0.738 0.262 0.000
H33.1 Retinoschisis and retinal cysts
0.738 0.262 0.000
I69 Sequelae of cerebrovascular disease
0.737 0.263 0.000
I25.5 Ischaemic cardiomyopathy
0.736 0.264 0.000
C79 Secondary malignant neoplasm of other sites
0.735 0.265 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.734 0.266 0.000
S67 Crushing injury of wrist and hand
0.732 0.268 0.000
F99-F99 Unspecified mental disorder
0.732 0.268 0.000
D03 Melanoma in situ
0.732 0.268 0.000
I38 Endocarditis, valve unspecified
0.731 0.269 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.730 0.270 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.730 0.270 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.729 0.271 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.729 0.271 0.000
D69.6 Thrombocytopenia, unspecified
0.728 0.272 0.000
D68 Other coagulation defects
0.728 0.272 0.000
T51 Toxic effect of alcohol
0.727 0.273 0.000
N00-N08 Glomerular diseases
0.727 0.273 0.000
S68 Traumatic amputation of wrist and hand
0.726 0.274 0.000
S80-S89 Injuries to the knee and lower leg
0.725 0.275 0.000
S42 Fracture of shoulder and upper arm
0.724 0.276 0.000
N30-N39 Other diseases of urinary system
0.723 0.277 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.723 0.277 0.000
I63.8 Other cerebral infarction
0.721 0.279 0.000
C71 Malignant neoplasm of brain
0.721 0.279 0.000
S51 Open wound of forearm
0.721 0.279 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.721 0.279 0.000
N60.3 Fibrosclerosis of breast
0.720 0.280 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.719 0.281 0.000
S62 Fracture at wrist and hand level
0.719 0.281 0.000
H57 Other disorders of eye and adnexa
0.719 0.281 0.000
F32.9 Depressive episode, unspecified
0.718 0.282 0.000
D06 Carcinoma in situ of cervix uteri
0.718 0.282 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.718 0.282 0.000
D73 Diseases of spleen
0.717 0.283 0.000
N76 Other inflammation of vagina and vulva
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
D22.0 Melanocytic naevi of lip
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
A30-A49 Other bacterial diseases
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
H31 Other disorders of choroid
0.716 0.284 0.000
H30 Chorioretinal inflammation
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.715 0.284 0.000
G93 Other disorders of brain
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.713 0.287 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.712 0.288 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.712 0.288 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.712 0.288 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.712 0.288 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.711 0.288 0.000
H33.5 Other retinal detachments
0.711 0.289 0.000
I42.2 Other hypertrophic cardiomyopathy
0.711 0.289 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.707 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
H35.9 Retinal disorder, unspecified
0.705 0.295 0.000
H35.7 Separation of retinal layers
0.705 0.295 0.000
H35.5 Hereditary retinal dystrophy
0.705 0.295 0.000
H35.2 Other proliferative retinopathy
0.705 0.295 0.000
H35.1 Retinopathy of prematurity
0.705 0.295 0.000
D05.7 Other carcinoma in situ of breast
0.705 0.295 0.000
N80 Endometriosis
0.704 0.296 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.703 0.297 0.000
W00-W19 Falls
0.702 0.298 0.000
H40 Glaucoma
0.701 0.299 0.000
F32.0 Mild depressive episode
0.701 0.299 0.000
E10 Insulin-dependent diabetes mellitus
0.701 0.299 0.000
D09.0 Bladder
0.699 0.300 0.000
V80-V89 Other land transport accidents
0.699 0.300 0.000
F25 Schizoaffective disorders
0.699 0.301 0.000
F29 Unspecified nonorganic psychosis
0.699 0.301 0.000
F28 Other nonorganic psychotic disorders
0.699 0.301 0.000
F24 Induced delusional disorder
0.699 0.301 0.000
F21 Schizotypal disorder
0.699 0.301 0.000
T31.0 Burns involving less than 10% of body surface
0.699 0.301 0.000
J30-J39 Other diseases of upper respiratory tract
0.699 0.301 0.000
E70-E90 Metabolic disorders
0.698 0.302 0.000
Y40 Systemic antibiotics
0.697 0.303 0.000
S09.9 Unspecified injury of head
0.696 0.304 0.000
S69 Other and unspecified injuries of wrist and hand
0.696 0.304 0.000
S65 Injury of blood vessels at wrist and hand level
0.696 0.304 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.695 0.305 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.694 0.306 0.000
I44.2 Atrioventricular block, complete
0.694 0.306 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
I33.0 Acute and subacute infective endocarditis
0.693 0.307 0.000
N30 Cystitis
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.307 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.692 0.308 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.692 0.308 0.000
I08 Multiple valve diseases
0.691 0.308 0.000
I44.7 Left bundle-branch block, unspecified
0.691 0.309 0.000
H25-H28 Disorders of lens
0.691 0.309 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.691 0.309 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.691 0.309 0.000
H43 Disorders of vitreous body
0.688 0.312 0.000
I42.8 Other cardiomyopathies
0.687 0.313 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.687 0.313 0.000
I42.6 Alcoholic cardiomyopathy
0.687 0.313 0.000
I42.5 Other restrictive cardiomyopathy
0.687 0.313 0.000
I42.4 Endocardial fibroelastosis
0.687 0.313 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.687 0.313 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.687 0.313 0.000
G20-G26 Extrapyramidal and movement disorders
0.685 0.315 0.000
N80.1 Endometriosis of ovary
0.685 0.315 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.684 0.316 0.000
Y43.3 Other antineoplastic drugs
0.684 0.316 0.000
I25.6 Silent myocardial ischaemia
0.683 0.317 0.000
I25.4 Coronary artery aneurysm
0.683 0.317 0.000
I25.3 Aneurysm of heart
0.683 0.317 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.683 0.317 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.682 0.318 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.682 0.318 0.000
I67.5 Moyamoya disease
0.682 0.318 0.000
I67.4 Hypertensive encephalopathy
0.682 0.318 0.000
I67.3 Progressive vascular leukoencephalopathy
0.682 0.318 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.682 0.318 0.000
D07.5 Prostate
0.681 0.319 0.000
Y44 Agents primarily affecting blood constituents
0.681 0.319 0.000
J09-J18 Influenza and pneumonia
0.681 0.319 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.680 0.320 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.680 0.320 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.679 0.321 0.000
E50-E64 Other nutritional deficiencies
0.679 0.321 0.000
H34.2 Other retinal artery occlusions
0.678 0.322 0.000
V10-V19 Pedal cyclist injured in transport accident
0.677 0.323 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.677 0.323 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.677 0.323 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.677 0.323 0.000
F38 Other mood [affective] disorders
0.676 0.324 0.000
F34 Persistent mood [affective] disorders
0.676 0.324 0.000
F30 Manic episode
0.676 0.324 0.000
F39 Unspecified mood [affective] disorder
0.676 0.324 0.000
I49.8 Other specified cardiac arrhythmias
0.676 0.324 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.675 0.325 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.675 0.325 0.000
D11 Benign neoplasm of major salivary glands
0.674 0.326 0.000
I50.0 Congestive heart failure
0.674 0.326 0.000
C51-C58 Malignant neoplasms of female genital organs
0.673 0.327 0.000
X60-X84 Intentional self-harm
0.673 0.327 0.000
D31 Benign neoplasm of eye and adnexa
0.673 0.327 0.000
D30 Benign neoplasm of urinary organs
0.673 0.327 0.000
D29 Benign neoplasm of male genital organs
0.673 0.327 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.673 0.327 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.673 0.327 0.000
D19 Benign neoplasm of mesothelial tissue
0.673 0.327 0.000
D16 Benign neoplasm of bone and articular cartilage
0.673 0.327 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.673 0.327 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.673 0.327 0.000
I44.3 Other and unspecified atrioventricular block
0.671 0.329 0.000
G95 Other diseases of spinal cord
0.670 0.330 0.000
T43.2 Other and unspecified antidepressants
0.669 0.331 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.669 0.331 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.668 0.332 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.668 0.332 0.000
Y35-Y36 Legal intervention and operations of war
0.668 0.332 0.000
Y10-Y34 Event of undetermined intent
0.668 0.332 0.000
Y00-Y09 Assault
0.668 0.332 0.000
X85-X99 Assault
0.668 0.332 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.668 0.332 0.000
X50-X57 Overexertion, travel and privation
0.668 0.332 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.668 0.332 0.000
X30-X39 Exposure to forces of nature
0.668 0.332 0.000
X20-X29 Contact with venomous animals and plants
0.668 0.332 0.000
X10-X19 Contact with heat and hot substances
0.668 0.332 0.000
X00-X09 Exposure to smoke, fire and flames
0.668 0.332 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.668 0.332 0.000
W75-W84 Other accidental threats to breathing
0.668 0.332 0.000
W65-W74 Accidental drowning and submersion
0.668 0.332 0.000
W50-W64 Exposure to animate mechanical forces
0.668 0.332 0.000
V98-V99 Other and unspecified transport accidents
0.668 0.332 0.000
V95-V97 Air and space transport accidents
0.668 0.332 0.000
V90-V94 Water transport accidents
0.668 0.332 0.000
V70-V79 Bus occupant injured in transport accident
0.668 0.332 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.668 0.332 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.668 0.332 0.000
V40-V49 Car occupant injured in transport accident
0.668 0.332 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.668 0.332 0.000
V01-V09 Pedestrian injured in transport accident
0.668 0.332 0.000
N99-N99 Other disorders of the genitourinary system
0.668 0.332 0.000
F32.1 Moderate depressive episode
0.668 0.332 0.000
N62 Hypertrophy of breast
0.667 0.333 0.000
I10-I15 Hypertensive diseases
0.666 0.334 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.664 0.336 0.000
J81 Pulmonary oedema
0.664 0.336 0.000
S32 Fracture of lumbar spine and pelvis
0.663 0.336 0.000
G30-G32 Other degenerative diseases of the nervous system
0.662 0.338 0.000
N10 Acute tubulo-interstitial nephritis
0.662 0.338 0.000
D25.2 Subserosal leiomyoma of uterus
0.662 0.338 0.000
F20.8 Other schizophrenia
0.662 0.338 0.000
F20.6 Simple schizophrenia
0.662 0.338 0.000
F20.5 Residual schizophrenia
0.662 0.338 0.000
F20.4 Postschizophrenic depression
0.662 0.338 0.000
F20.3 Undifferentiated schizophrenia
0.662 0.338 0.000
F20.2 Catatonic schizophrenia
0.662 0.338 0.000
F20.1 Hebephrenic schizophrenia
0.662 0.338 0.000
L28 Lichen simplex chronicus and prurigo
0.661 0.339 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.660 0.340 0.000
N30.9 Cystitis, unspecified
0.657 0.343 0.000
C50 Malignant neoplasm of breast
0.656 0.344 0.000
T66-T78 Other and unspecified effects of external causes
0.656 0.344 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.655 0.345 0.000
S61.8 Open wound of other parts of wrist and hand
0.655 0.345 0.000
N93 Other abnormal uterine and vaginal bleeding
0.655 0.345 0.000
H33.4 Traction detachment of retina
0.655 0.345 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.654 0.345 0.000
G90 Disorders of autonomic nervous system
0.654 0.345 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.654 0.345 0.000
G92 Toxic encephalopathy
0.654 0.345 0.000
I31.3 Pericardial effusion (noninflammatory)
0.654 0.346 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.654 0.346 0.000
H55 Nystagmus and other irregular eye movements
0.653 0.347 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.652 0.348 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.652 0.348 0.000
G91 Hydrocephalus
0.651 0.348 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.651 0.349 0.000
Y95 Nosocomial condition
0.650 0.350 0.000
N71 Inflammatory disease of uterus, except cervix
0.650 0.350 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.649 0.350 0.000
H34.9 Retinal vascular occlusion, unspecified
0.649 0.351 0.000
H34.1 Central retinal artery occlusion
0.649 0.351 0.000
H34.0 Transient retinal artery occlusion
0.649 0.351 0.000
I71 Aortic aneurysm and dissection
0.649 0.351 0.000
A41 Other septicaemia
0.649 0.351 0.000
E13 Other specified diabetes mellitus
0.648 0.351 0.000
I72 Other aneurysm
0.648 0.352 0.000
I51.9 Heart disease, unspecified
0.648 0.352 0.000
S52 Fracture of forearm
0.647 0.353 0.000
S92 Fracture of foot, except ankle
0.646 0.354 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.645 0.354 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.645 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.645 0.354 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.645 0.354 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.645 0.354 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.645 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.645 0.354 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.645 0.354 0.000
T36 Poisoning by systemic antibiotics
0.645 0.354 0.000
S70-S79 Injuries to the hip and thigh
0.645 0.355 0.000
D10 Benign neoplasm of mouth and pharynx
0.645 0.355 0.000
T63 Toxic effect of contact with venomous animals
0.642 0.357 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.642 0.358 0.000
H40.0 Glaucoma suspect
0.642 0.358 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.642 0.358 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.641 0.358 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.641 0.359 0.000
E10.4 With neurological complications
0.641 0.359 0.000
J90-J94 Other diseases of pleura
0.640 0.360 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.639 0.361 0.000
T51.0 Ethanol
0.639 0.361 0.000
D80-D89 Certain disorders involving the immune mechanism
0.638 0.362 0.000
I35.1 Aortic (valve) insufficiency
0.638 0.362 0.000
D07.1 Vulva
0.638 0.362 0.000
J42 Unspecified chronic bronchitis
0.637 0.362 0.000
G35 Multiple sclerosis
0.637 0.363 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.637 0.363 0.000
N88 Other noninflammatory disorders of cervix uteri
0.637 0.363 0.000
A80-A89 Viral infections of the central nervous system
0.636 0.364 0.000
D67 Hereditary factor IX deficiency
0.636 0.364 0.000
D66 Hereditary factor VIII deficiency
0.636 0.364 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.636 0.364 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.636 0.364 0.000
J47 Bronchiectasis
0.636 0.364 0.000
I60 Subarachnoid haemorrhage
0.635 0.365 0.000
T39.1 4-Aminophenol derivatives
0.635 0.365 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.634 0.365 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.634 0.366 0.000
L27 Dermatitis due to substances taken internally
0.634 0.366 0.000
I24 Other acute ischaemic heart diseases
0.634 0.366 0.000
T20 Burn and corrosion of head and neck
0.633 0.367 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.632 0.368 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.631 0.369 0.000
N25-N29 Other disorders of kidney and ureter
0.630 0.370 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.630 0.370 0.000
D74 Methaemoglobinaemia
0.630 0.370 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.630 0.370 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.630 0.370 0.000
S51.9 Open wound of forearm, part unspecified
0.630 0.370 0.000
L40-L45 Papulosquamous disorders
0.629 0.371 0.000
F01 Vascular dementia
0.629 0.371 0.000
I44.6 Other and unspecified fascicular block
0.629 0.371 0.000
I44.5 Left posterior fascicular block
0.629 0.371 0.000
I44.4 Left anterior fascicular block
0.629 0.371 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.629 0.371 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.629 0.371 0.000
Y59 Other and unspecified vaccines and biological substances
0.628 0.372 0.000
Y58 Bacterial vaccines
0.628 0.372 0.000
Y57 Other and unspecified drugs and medicaments
0.628 0.372 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.628 0.372 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.628 0.372 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.628 0.372 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.628 0.372 0.000
Y52 Agents primarily affecting the cardiovascular system
0.628 0.372 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.628 0.372 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.628 0.372 0.000
Y48 Anaesthetics and therapeutic gases
0.628 0.372 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.628 0.372 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.628 0.372 0.000
H44 Disorders of globe
0.626 0.374 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.625 0.375 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.625 0.375 0.000
H16 Keratitis
0.624 0.376 0.000
I67.1 Cerebral aneurysm, nonruptured
0.624 0.376 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.623 0.376 0.000
F22.9 Persistent delusional disorder, unspecified
0.623 0.377 0.000
F22.8 Other persistent delusional disorders
0.623 0.377 0.000
F31 Bipolar affective disorder
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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