TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs116990435
log Bayes Factor = 16.0291
Chromosome 21   position 42,048,274  (GRCh37) Explore rs116990435 on Ensembl!
Variant rs116990435 is part of Cluster X0271

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.995 0.005 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.994 0.006 0.000
S60-S69 Injuries to the wrist and hand
0.993 0.007 0.000
Z92 Personal history of medical treatment
0.992 0.008 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.991 0.009 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.991 0.009 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.990 0.010 0.000
I50 Heart failure
0.987 0.013 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.987 0.013 0.000
I51 Complications and ill-defined descriptions of heart disease
0.987 0.013 0.000
G56 Mononeuropathies of upper limb
0.980 0.020 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
Z86 Personal history of certain other diseases
0.977 0.023 0.000
I80 Phlebitis and thrombophlebitis
0.977 0.023 0.000
I20 Angina pectoris
0.975 0.025 0.000
I51.7 Cardiomegaly
0.973 0.027 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.972 0.028 0.000
G56.0 Carpal tunnel syndrome
0.968 0.032 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.966 0.034 0.000
Z86.4 Personal history of psychoactive substance abuse
0.965 0.035 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.963 0.037 0.000
I20.9 Angina pectoris, unspecified
0.959 0.041 0.000
M50-M54 Other dorsopathies
0.949 0.051 0.000
F10.2 Dependence syndrome
0.944 0.056 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.943 0.057 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.941 0.059 0.000
I49 Other cardiac arrhythmias
0.941 0.059 0.000
I50.0 Congestive heart failure
0.936 0.064 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.925 0.075 0.000
Chapter XX External causes of morbidity and mortality
0.924 0.076 0.000
I46 Cardiac arrest
0.923 0.077 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.918 0.082 0.000
F10.0 Acute intoxication
0.917 0.083 0.000
S64 Injury of nerves at wrist and hand level
0.914 0.086 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.912 0.088 0.000
G90-G99 Other disorders of the nervous system
0.910 0.090 0.000
M54 Dorsalgia
0.904 0.096 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.888 0.112 0.000
I49.9 Cardiac arrhythmia, unspecified
0.888 0.112 0.000
F10.3 Withdrawal state
0.884 0.116 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.883 0.117 0.000
I44 Atrioventricular and left bundle-branch block
0.883 0.117 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.880 0.120 0.000
I50.1 Left ventricular failure
0.876 0.124 0.000
I95 Hypotension
0.875 0.125 0.000
F10.1 Harmful use
0.873 0.127 0.000
G40-G47 Episodic and paroxysmal disorders
0.872 0.128 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.870 0.130 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.864 0.136 0.000
Z95.4 Presence of other heart-valve replacement
0.864 0.136 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.862 0.138 0.000
M54.9 Dorsalgia, unspecified
0.861 0.139 0.000
I50.9 Heart failure, unspecified
0.861 0.139 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.859 0.140 0.000
S62 Fracture at wrist and hand level
0.859 0.141 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.855 0.145 0.000
I72 Other aneurysm
0.853 0.147 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.853 0.147 0.000
G20-G26 Extrapyramidal and movement disorders
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.843 0.157 0.000
S61 Open wound of wrist and hand
0.842 0.158 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.835 0.165 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.832 0.168 0.000
Chapter II Neoplasms
0.832 0.168 0.000
I45 Other conduction disorders
0.828 0.172 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.826 0.174 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.825 0.175 0.000
G93 Other disorders of brain
0.825 0.175 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.822 0.178 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.820 0.180 0.000
Z95.0 Presence of cardiac pacemaker
0.818 0.182 0.000
I44.7 Left bundle-branch block, unspecified
0.817 0.183 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.816 0.184 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.815 0.185 0.000
S64.4 Injury of digital nerve of other finger
0.815 0.185 0.000
M51 Other intervertebral disk disorders
0.812 0.188 0.000
F60-F69 Disorders of adult personality and behaviour
0.811 0.189 0.000
I46.0 Cardiac arrest with successful resuscitation
0.811 0.189 0.000
I86 Varicose veins of other sites
0.809 0.191 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.808 0.192 0.000
S90-S99 Injuries to the ankle and foot
0.808 0.192 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.808 0.192 0.000
Z95.2 Presence of prosthetic heart valve
0.808 0.192 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.807 0.193 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.806 0.194 0.000
G56.2 Lesion of ulnar nerve
0.804 0.196 0.000
Chapter XXII Codes for special purposes
0.804 0.196 0.000
S60 Superficial injury of wrist and hand
0.803 0.197 0.000
I47 Paroxysmal tachycardia
0.801 0.199 0.000
I95.9 Hypotension, unspecified
0.800 0.200 0.000
I42 Cardiomyopathy
0.799 0.201 0.000
I46.9 Cardiac arrest, unspecified
0.794 0.206 0.000
S61.0 Open wound of finger(s) without damage to nail
0.793 0.207 0.000
G54 Nerve root and plexus disorders
0.791 0.209 0.000
I51.8 Other ill-defined heart diseases
0.786 0.214 0.000
D00-D09 In situ neoplasms
0.786 0.214 0.000
M20-M25 Other joint disorders
0.786 0.214 0.000
G70-G73 Diseases of myoneural junction and muscle
0.785 0.215 0.000
I26 Pulmonary embolism
0.782 0.218 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.780 0.220 0.000
I49.1 Atrial premature depolarisation
0.779 0.221 0.000
I36 Nonrheumatic tricuspid valve disorders
0.779 0.221 0.000
M45-M49 Spondylopathies
0.778 0.222 0.000
Chapter VIII Diseases of the ear and mastoid process
0.774 0.226 0.000
I95.1 Orthostatic hypotension
0.773 0.227 0.000
I37 Pulmonary valve disorders
0.772 0.228 0.000
S68 Traumatic amputation of wrist and hand
0.770 0.230 0.000
G30-G32 Other degenerative diseases of the nervous system
0.769 0.231 0.000
Z86.7 Personal history of diseases of the circulatory system
0.769 0.231 0.000
I74 Arterial embolism and thrombosis
0.768 0.231 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.768 0.232 0.000
S64.3 Injury of digital nerve of thumb
0.768 0.232 0.000
I78 Diseases of capillaries
0.767 0.233 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.767 0.233 0.000
G47 Sleep disorders
0.766 0.234 0.000
I87 Other disorders of veins
0.766 0.234 0.000
Z86.0 Personal history of other neoplasms
0.765 0.235 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.763 0.237 0.000
M50 Cervical disk disorders
0.761 0.239 0.000
Z89 Acquired absence of limb
0.760 0.239 0.000
I70 Atherosclerosis
0.760 0.240 0.000
S40-S49 Injuries to the shoulder and upper arm
0.759 0.241 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.758 0.242 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.757 0.243 0.000
S70-S79 Injuries to the hip and thigh
0.756 0.244 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.755 0.245 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.752 0.248 0.000
S00-S09 Injuries to the head
0.752 0.248 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.752 0.248 0.000
I44.1 Atrioventricular block, second degree
0.752 0.248 0.000
I21 Acute myocardial infarction
0.750 0.250 0.000
M05-M14 Inflammatory polyarthropathies
0.748 0.252 0.000
Chapter X Diseases of the respiratory system
0.747 0.253 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.747 0.253 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
S50-S59 Injuries to the elbow and forearm
0.744 0.256 0.000
G20 Parkinson's disease
0.743 0.257 0.000
I71 Aortic aneurysm and dissection
0.743 0.257 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.743 0.257 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.743 0.257 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
I77 Other disorders of arteries and arterioles
0.743 0.257 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.743 0.257 0.000
Y52 Agents primarily affecting the cardiovascular system
0.742 0.258 0.000
Z92.8 Personal history of other medical treatment
0.739 0.261 0.000
G90 Disorders of autonomic nervous system
0.738 0.262 0.000
I22 Subsequent myocardial infarction
0.738 0.262 0.000
S80-S89 Injuries to the knee and lower leg
0.735 0.265 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.734 0.266 0.000
I49.3 Ventricular premature depolarisation
0.734 0.266 0.000
I83 Varicose veins of lower extremities
0.733 0.267 0.000
I20.0 Unstable angina
0.732 0.268 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.731 0.269 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.731 0.269 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.730 0.270 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.730 0.270 0.000
M60-M63 Disorders of muscles
0.730 0.270 0.000
M80-M85 Disorders of bone density and structure
0.729 0.271 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.728 0.272 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
I85 Oesophageal varices
0.725 0.275 0.000
I72.4 Aneurysm of artery of lower extremity
0.725 0.275 0.000
G58 Other mononeuropathies
0.724 0.276 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.724 0.276 0.000
Z88.6 Personal history of allergy to analgesic agent
0.724 0.276 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
S67 Crushing injury of wrist and hand
0.722 0.278 0.000
S62.6 Fracture of other finger
0.721 0.279 0.000
Z22 Carrier of infectious disease
0.720 0.279 0.000
I25.1 Atherosclerotic heart disease
0.720 0.280 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.719 0.281 0.000
I51.9 Heart disease, unspecified
0.718 0.282 0.000
F99-F99 Unspecified mental disorder
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.717 0.283 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
M54.4 Lumbago with sciatica
0.715 0.285 0.000
M51.2 Other specified intervertebral disk displacement
0.714 0.286 0.000
M54.3 Sciatica
0.714 0.286 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.712 0.287 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.712 0.287 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.712 0.287 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.712 0.287 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.712 0.287 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.712 0.287 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.712 0.287 0.000
F11 Mental and behavioural disorders due to use of opioids
0.712 0.287 0.000
I30 Acute pericarditis
0.712 0.288 0.000
S69 Other and unspecified injuries of wrist and hand
0.712 0.288 0.000
S65 Injury of blood vessels at wrist and hand level
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
G93.3 Postviral fatigue syndrome
0.712 0.288 0.000
C64-C68 Malignant neoplasms of urinary tract
0.711 0.289 0.000
Z92.9 Personal history of medical treatment, unspecified
0.711 0.289 0.000
Z92.5 Personal history of rehabilitation measures
0.711 0.289 0.000
F10.9 Unspecified mental and behavioural disorder
0.711 0.289 0.000
F10.8 Other mental and behavioural disorders
0.711 0.289 0.000
F10.7 Residual and late-onset psychotic disorder
0.711 0.289 0.000
F10.6 Amnesic syndrome
0.711 0.289 0.000
F10.5 Psychotic disorder
0.711 0.289 0.000
F10.4 Withdrawal state with delirium
0.711 0.289 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.710 0.290 0.000
G52 Disorders of other cranial nerves
0.710 0.290 0.000
M54.1 Radiculopathy
0.710 0.290 0.000
I05-I09 Chronic rheumatic heart diseases
0.710 0.290 0.000
I47.2 Ventricular tachycardia
0.709 0.291 0.000
I88 Nonspecific lymphadenitis
0.708 0.292 0.000
I82 Other venous embolism and thrombosis
0.708 0.292 0.000
I81 Portal vein thrombosis
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
I51.6 Cardiovascular disease, unspecified
0.707 0.293 0.000
I51.5 Myocardial degeneration
0.707 0.293 0.000
I51.4 Myocarditis, unspecified
0.707 0.293 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.707 0.293 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.707 0.293 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.707 0.293 0.000
I51.0 Cardiac septal defect, acquired
0.707 0.293 0.000
G59.0 Diabetic mononeuropathy
0.706 0.294 0.000
I72.8 Aneurysm of other specified arteries
0.706 0.294 0.000
Q80-Q89 Other congenital malformations
0.706 0.294 0.000
X60-X84 Intentional self-harm
0.705 0.294 0.000
G62 Other polyneuropathies
0.705 0.295 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
I49.4 Other and unspecified premature depolarisation
0.704 0.296 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.704 0.296 0.000
M25 Other joint disorders, not elsewhere classified
0.703 0.297 0.000
F03 Unspecified dementia
0.703 0.297 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.703 0.297 0.000
G56.8 Other mononeuropathies of upper limb
0.703 0.297 0.000
G56.4 Causalgia
0.703 0.297 0.000
G56.3 Lesion of radial nerve
0.703 0.297 0.000
G56.1 Other lesions of median nerve
0.703 0.297 0.000
S61.7 Multiple open wounds of wrist and hand
0.703 0.297 0.000
M65-M68 Disorders of synovium and tendon
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
I25.4 Coronary artery aneurysm
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.701 0.299 0.000
C91 Lymphoid leukaemia
0.700 0.300 0.000
J40-J47 Chronic lower respiratory diseases
0.699 0.301 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.696 0.304 0.000
I35 Nonrheumatic aortic valve disorders
0.694 0.306 0.000
I73 Other peripheral vascular diseases
0.694 0.306 0.000
I10-I15 Hypertensive diseases
0.692 0.308 0.000
Z95.1 Presence of aortocoronary bypass graft
0.692 0.308 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.691 0.308 0.000
T90 Sequelae of injuries of head
0.691 0.308 0.000
G40 Epilepsy
0.691 0.309 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.690 0.310 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.690 0.310 0.000
I24 Other acute ischaemic heart diseases
0.690 0.310 0.000
G93.8 Other specified disorders of brain
0.689 0.310 0.000
I45.1 Other and unspecified right bundle-branch block
0.686 0.314 0.000
V10-V19 Pedal cyclist injured in transport accident
0.685 0.315 0.000
I20.1 Angina pectoris with documented spasm
0.684 0.315 0.000
M13 Other arthritis
0.684 0.316 0.000
M54.6 Pain in thoracic spine
0.684 0.316 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.683 0.317 0.000
I20.8 Other forms of angina pectoris
0.682 0.318 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.682 0.318 0.000
Y44 Agents primarily affecting blood constituents
0.681 0.319 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.681 0.319 0.000
M53 Other dorsopathies, not elsewhere classified
0.680 0.319 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
L40-L45 Papulosquamous disorders
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
G95 Other diseases of spinal cord
0.679 0.321 0.000
F60 Specific personality disorders
0.678 0.322 0.000
Z92.0 Personal history of contraception
0.678 0.322 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.675 0.325 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.675 0.325 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.675 0.325 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.675 0.325 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.675 0.325 0.000
Z82.2 Family history of deafness and hearing loss
0.675 0.325 0.000
Z82.1 Family history of blindness and visual loss
0.675 0.325 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.675 0.325 0.000
I49.2 Junctional premature depolarisation
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.674 0.326 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.674 0.326 0.000
M31 Other necrotising vasculopathies
0.674 0.326 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.672 0.328 0.000
D09 Carcinoma in situ of other and unspecified sites
0.671 0.329 0.000
Q00-Q07 Congenital malformations of the nervous system
0.671 0.329 0.000
D03 Melanoma in situ
0.670 0.330 0.000
M40-M43 Deforming dorsopathies
0.669 0.331 0.000
I31 Other diseases of pericardium
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.668 0.331 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.668 0.332 0.000
Z95.3 Presence of xenogenic heart valve
0.666 0.333 0.000
I86.1 Scrotal varices
0.666 0.334 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.666 0.334 0.000
M47 Spondylosis
0.665 0.335 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.664 0.336 0.000
Q50-Q56 Congenital malformations of genital organs
0.664 0.336 0.000
C83.3 Large cell (diffuse)
0.664 0.336 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.663 0.337 0.000
I99 Other and unspecified disorders of circulatory system
0.663 0.337 0.000
I42.0 Dilated cardiomyopathy
0.663 0.337 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.663 0.337 0.000
Y35-Y36 Legal intervention and operations of war
0.663 0.337 0.000
Y10-Y34 Event of undetermined intent
0.663 0.337 0.000
Y00-Y09 Assault
0.663 0.337 0.000
X85-X99 Assault
0.663 0.337 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.663 0.337 0.000
X50-X57 Overexertion, travel and privation
0.663 0.337 0.000
X30-X39 Exposure to forces of nature
0.663 0.337 0.000
X20-X29 Contact with venomous animals and plants
0.663 0.337 0.000
X10-X19 Contact with heat and hot substances
0.663 0.337 0.000
X00-X09 Exposure to smoke, fire and flames
0.663 0.337 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.663 0.337 0.000
W75-W84 Other accidental threats to breathing
0.663 0.337 0.000
W65-W74 Accidental drowning and submersion
0.663 0.337 0.000
W50-W64 Exposure to animate mechanical forces
0.663 0.337 0.000
V98-V99 Other and unspecified transport accidents
0.663 0.337 0.000
V95-V97 Air and space transport accidents
0.663 0.337 0.000
V90-V94 Water transport accidents
0.663 0.337 0.000
V70-V79 Bus occupant injured in transport accident
0.663 0.337 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.663 0.337 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.663 0.337 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.663 0.337 0.000
V01-V09 Pedestrian injured in transport accident
0.663 0.337 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.662 0.338 0.000
I46.1 Sudden cardiac death, so described
0.662 0.338 0.000
T66-T78 Other and unspecified effects of external causes
0.661 0.339 0.000
S09 Other and unspecified injuries of head
0.660 0.339 0.000
Z97 Presence of other devices
0.659 0.341 0.000
I25.5 Ischaemic cardiomyopathy
0.657 0.343 0.000
G47.3 Sleep apnoea
0.657 0.343 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.656 0.344 0.000
J45 Asthma
0.656 0.344 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.655 0.344 0.000
S64.8 Injury of other nerves at wrist and hand level
0.655 0.344 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.655 0.344 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.655 0.344 0.000
S64.1 Injury of median nerve at wrist and hand level
0.655 0.344 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.655 0.344 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.654 0.346 0.000
T18 Foreign body in alimentary tract
0.653 0.347 0.000
S51 Open wound of forearm
0.652 0.347 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G96 Other disorders of central nervous system
0.652 0.348 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.652 0.348 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G92 Toxic encephalopathy
0.652 0.348 0.000
Y43 Primarily systemic agents
0.652 0.348 0.000
I34 Nonrheumatic mitral valve disorders
0.651 0.349 0.000
Q21 Congenital malformations of cardiac septa
0.650 0.350 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.650 0.350 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.650 0.350 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.649 0.351 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.648 0.352 0.000
M54.8 Other dorsalgia
0.648 0.352 0.000
M54.0 Panniculitis affecting regions of neck and back
0.648 0.352 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.648 0.352 0.000
Y57 Other and unspecified drugs and medicaments
0.647 0.353 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.645 0.355 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.644 0.356 0.000
D05 Carcinoma in situ of breast
0.643 0.357 0.000
S62.3 Fracture of other metacarpal bone
0.640 0.359 0.000
T92 Sequelae of injuries of upper limb
0.640 0.360 0.000
C85.1 B-cell lymphoma, unspecified
0.639 0.361 0.000
I49.5 Sick sinus syndrome
0.639 0.361 0.000
M13.9 Arthritis, unspecified
0.638 0.362 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.638 0.362 0.000
S62.61 Fracture of other finger (open)
0.638 0.362 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.638 0.362 0.000
I89.0 Lymphoedema, not elsewhere classified
0.638 0.362 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.637 0.363 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.637 0.363 0.000
Q35-Q37 Cleft lip and cleft palate
0.637 0.363 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.637 0.363 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.637 0.363 0.000
F01 Vascular dementia
0.637 0.363 0.000
M25.7 Osteophyte
0.637 0.363 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.636 0.363 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.636 0.364 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.636 0.364 0.000
T93 Sequelae of injuries of lower limb
0.635 0.365 0.000
S91 Open wound of ankle and foot
0.634 0.366 0.000
G51 Facial nerve disorders
0.634 0.366 0.000
I44.6 Other and unspecified fascicular block
0.633 0.367 0.000
I44.5 Left posterior fascicular block
0.633 0.367 0.000
I44.4 Left anterior fascicular block
0.633 0.367 0.000
I44.3 Other and unspecified atrioventricular block
0.633 0.367 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.633 0.367 0.000
S32 Fracture of lumbar spine and pelvis
0.633 0.367 0.000
I45.5 Other specified heart block
0.633 0.367 0.000
I38 Endocarditis, valve unspecified
0.632 0.368 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.631 0.369 0.000
F06.7 Mild cognitive disorder
0.631 0.369 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.631 0.369 0.000
I89.1 Lymphangitis
0.630 0.370 0.000
J44 Other chronic obstructive pulmonary disease
0.630 0.370 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.628 0.372 0.000
H80-H83 Diseases of inner ear
0.628 0.372 0.000
I95.8 Other hypotension
0.627 0.373 0.000
I95.0 Idiopathic hypotension
0.627 0.373 0.000
I78.1 Naevus, nonneoplastic
0.627 0.373 0.000
Z91.6 Personal history of other physical trauma
0.625 0.374 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.625 0.375 0.000
G41 Status epilepticus
0.625 0.375 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.625 0.375 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.625 0.375 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.624 0.376 0.000
F02 Dementia in other diseases classified elsewhere
0.624 0.376 0.000
F09 Unspecified organic or symptomatic mental disorder
0.624 0.376 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.624 0.376 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.624 0.376 0.000
Z22.3 Carrier of other specified bacterial diseases
0.621 0.379 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.621 0.379 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.620 0.380 0.000
Y59 Other and unspecified vaccines and biological substances
0.620 0.380 0.000
Y58 Bacterial vaccines
0.620 0.380 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.620 0.380 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.620 0.380 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.620 0.380 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.620 0.380 0.000
Y48 Anaesthetics and therapeutic gases
0.620 0.380 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.620 0.380 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.620 0.380 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.620 0.380 0.000
S20-S29 Injuries to the thorax
0.620 0.380 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.619 0.381 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.618 0.382 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.618 0.382 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.618 0.382 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.618 0.382 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.618 0.382 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.618 0.382 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.618 0.382 0.000
C91.1 Chronic lymphocytic leukaemia
0.618 0.382 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.617 0.382 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.617 0.382 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.617 0.382 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.617 0.382 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.617 0.382 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.617 0.382 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.617 0.382 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.617 0.382 0.000
I87.8 Other specified disorders of veins
0.617 0.383 0.000
G60 Hereditary and idiopathic neuropathy
0.616 0.384 0.000
G64 Other disorders of peripheral nervous system
0.616 0.384 0.000
G47.9 Sleep disorder, unspecified
0.616 0.384 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.616 0.384 0.000
S62.7 Multiple fractures of fingers
0.616 0.384 0.000
S62.5 Fracture of thumb
0.616 0.384 0.000
S62.4 Multiple fractures of metacarpal bones
0.616 0.384 0.000
S62.2 Fracture of first metacarpal bone
0.616 0.384 0.000
S62.1 Fracture of other carpal bone(s)
0.616 0.384 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.616 0.384 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.615 0.385 0.000
G90.2 Horner's syndrome
0.615 0.385 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.615 0.385 0.000
G63.2 Diabetic polyneuropathy
0.614 0.386 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.614 0.386 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.614 0.386 0.000
C81 Hodgkin's disease
0.613 0.387 0.000
I28 Other diseases of pulmonary vessels
0.613 0.387 0.000
S90 Superficial injury of ankle and foot
0.613 0.387 0.000
G45.3 Amaurosis fugax
0.613 0.387 0.000
I72.9 Aneurysm of unspecified site
0.612 0.388 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.612 0.388 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.612 0.388 0.000
I72.3 Aneurysm of iliac artery
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.