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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117041046
log Bayes Factor = 5.66753
Chromosome 20   position 57,482,240  (GRCh37) Explore rs117041046 on Ensembl!
Variant rs117041046 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.997 0.003 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.988 0.012 0.000
I10-I15 Hypertensive diseases
0.973 0.027 0.000
Chapter XXI Factors influencing health status and contact with health services
0.967 0.033 0.000
Chapter XIV Diseases of the genitourinary system
0.965 0.035 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.955 0.045 0.000
I10 Essential (primary) hypertension
0.954 0.046 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.952 0.048 0.000
K29 Gastritis and duodenitis
0.952 0.048 0.000
I25.2 Old myocardial infarction
0.947 0.053 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.946 0.054 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.941 0.059 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.936 0.064 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.930 0.070 0.000
K55-K64 Other diseases of intestines
0.926 0.074 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.925 0.075 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.922 0.078 0.000
K29.8 Duodenitis
0.915 0.085 0.000
Chapter XX External causes of morbidity and mortality
0.888 0.112 0.000
I20 Angina pectoris
0.886 0.114 0.000
Z86 Personal history of certain other diseases
0.885 0.115 0.000
Chapter VII Diseases of the eye and adnexa
0.879 0.121 0.000
N30-N39 Other diseases of urinary system
0.872 0.128 0.000
Z86.4 Personal history of psychoactive substance abuse
0.862 0.138 0.000
M20-M25 Other joint disorders
0.855 0.145 0.000
I21 Acute myocardial infarction
0.849 0.151 0.000
K26 Duodenal ulcer
0.846 0.154 0.000
K90-K93 Other diseases of the digestive system
0.843 0.157 0.000
K25 Gastric ulcer
0.828 0.172 0.000
I25.1 Atherosclerotic heart disease
0.823 0.177 0.000
K22 Other diseases of oesophagus
0.815 0.185 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.814 0.186 0.000
K70-K77 Diseases of liver
0.812 0.188 0.000
I20.9 Angina pectoris, unspecified
0.812 0.188 0.000
N39 Other disorders of urinary system
0.810 0.190 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.810 0.190 0.000
Chapter II Neoplasms
0.808 0.192 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.805 0.195 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.804 0.196 0.000
K50-K52 Noninfective enteritis and colitis
0.801 0.199 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.801 0.199 0.000
K57 Diverticular disease of intestine
0.798 0.202 0.000
M05-M14 Inflammatory polyarthropathies
0.796 0.204 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.792 0.208 0.000
Z95.1 Presence of aortocoronary bypass graft
0.792 0.208 0.000
Chapter VI Diseases of the nervous system
0.789 0.211 0.000
N20-N23 Urolithiasis
0.785 0.215 0.000
M15-M19 Arthrosis
0.780 0.220 0.000
Z93 Artificial opening status
0.778 0.222 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.776 0.224 0.000
H25-H28 Disorders of lens
0.776 0.224 0.000
N99-N99 Other disorders of the genitourinary system
0.774 0.226 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.772 0.228 0.000
N10-N16 Renal tubulo-interstitial diseases
0.771 0.229 0.000
S60-S69 Injuries to the wrist and hand
0.771 0.229 0.000
K59 Other functional intestinal disorders
0.766 0.234 0.000
I24 Other acute ischaemic heart diseases
0.756 0.244 0.000
Z80 Family history of malignant neoplasm
0.755 0.245 0.000
K40-K46 Hernia
0.752 0.248 0.000
K31 Other diseases of stomach and duodenum
0.752 0.248 0.000
N39.0 Urinary tract infection, site not specified
0.752 0.248 0.000
M25 Other joint disorders, not elsewhere classified
0.752 0.248 0.000
N17-N19 Renal failure
0.746 0.253 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.744 0.256 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.744 0.256 0.000
S50-S59 Injuries to the elbow and forearm
0.738 0.262 0.000
H26 Other cataract
0.737 0.263 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.736 0.264 0.000
K29.5 Chronic gastritis, unspecified
0.735 0.265 0.000
K29.6 Other gastritis
0.735 0.265 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.733 0.266 0.000
Z95.0 Presence of cardiac pacemaker
0.733 0.267 0.000
Chapter VIII Diseases of the ear and mastoid process
0.733 0.267 0.000
S40-S49 Injuries to the shoulder and upper arm
0.732 0.268 0.000
K61 Abscess of anal and rectal regions
0.724 0.276 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.724 0.276 0.000
M70-M79 Other soft tissue disorders
0.719 0.281 0.000
K65-K67 Diseases of peritoneum
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I05-I09 Chronic rheumatic heart diseases
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I22 Subsequent myocardial infarction
0.716 0.284 0.000
K92 Other diseases of digestive system
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.714 0.285 0.000
I25.5 Ischaemic cardiomyopathy
0.714 0.285 0.000
I25.4 Coronary artery aneurysm
0.714 0.285 0.000
I25.3 Aneurysm of heart
0.714 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.714 0.285 0.000
K63 Other diseases of intestine
0.713 0.286 0.000
M65-M68 Disorders of synovium and tendon
0.713 0.287 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.713 0.287 0.000
S80-S89 Injuries to the knee and lower leg
0.712 0.287 0.000
H26.9 Cataract, unspecified
0.710 0.290 0.000
K28 Gastrojejunal ulcer
0.708 0.292 0.000
K27 Peptic ulcer, site unspecified
0.708 0.292 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.708 0.292 0.000
K21 Gastro-oesophageal reflux disease
0.706 0.294 0.000
M20 Acquired deformities of fingers and toes
0.706 0.294 0.000
T81 Complications of procedures, not elsewhere classified
0.701 0.299 0.000
I15 Secondary hypertension
0.697 0.303 0.000
I13 Hypertensive heart and renal disease
0.697 0.303 0.000
I11 Hypertensive heart disease
0.697 0.303 0.000
K35-K38 Diseases of appendix
0.695 0.305 0.000
D10-D36 Benign neoplasms
0.694 0.306 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.694 0.306 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.694 0.306 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.307 0.000
N60-N64 Disorders of breast
0.692 0.308 0.000
N00-N08 Glomerular diseases
0.692 0.308 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.691 0.309 0.000
K22.1 Ulcer of oesophagus
0.689 0.310 0.000
I21.9 Acute myocardial infarction, unspecified
0.689 0.311 0.000
I12 Hypertensive renal disease
0.689 0.311 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.684 0.316 0.000
Z97 Presence of other devices
0.684 0.316 0.000
Z94 Transplanted organ and tissue status
0.684 0.316 0.000
Z89 Acquired absence of limb
0.684 0.316 0.000
Z84 Family history of other conditions
0.684 0.316 0.000
Z83 Family history of other specific disorders
0.684 0.316 0.000
Z81 Family history of mental and behavioural disorders
0.684 0.316 0.000
M45-M49 Spondylopathies
0.684 0.316 0.000
K58 Irritable bowel syndrome
0.683 0.317 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.317 0.000
M91-M94 Chondropathies
0.683 0.317 0.000
M86-M90 Other osteopathies
0.683 0.317 0.000
M60-M63 Disorders of muscles
0.683 0.317 0.000
M40-M43 Deforming dorsopathies
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
N25-N29 Other disorders of kidney and ureter
0.682 0.317 0.000
K29.9 Gastroduodenitis, unspecified
0.682 0.317 0.000
K29.4 Chronic atrophic gastritis
0.682 0.317 0.000
K29.3 Chronic superficial gastritis
0.682 0.317 0.000
K29.2 Alcoholic gastritis
0.682 0.317 0.000
K29.1 Other acute gastritis
0.682 0.317 0.000
K29.0 Acute haemorrhagic gastritis
0.682 0.317 0.000
K52 Other non-infective gastro-enteritis and colitis
0.682 0.318 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.678 0.321 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.678 0.321 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.678 0.321 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.678 0.321 0.000
Z82.3 Family history of stroke
0.678 0.321 0.000
Z82.2 Family history of deafness and hearing loss
0.678 0.321 0.000
Z82.1 Family history of blindness and visual loss
0.678 0.321 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.678 0.321 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.678 0.322 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.676 0.324 0.000
N20 Calculus of kidney and ureter
0.675 0.325 0.000
E00-E07 Disorders of thyroid gland
0.674 0.326 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.673 0.327 0.000
N30 Cystitis
0.671 0.329 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.671 0.329 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.671 0.329 0.000
T79-T79 Certain early complications of trauma
0.671 0.329 0.000
T66-T78 Other and unspecified effects of external causes
0.671 0.329 0.000
T33-T35 Frostbite
0.671 0.329 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.671 0.329 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.671 0.329 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.671 0.329 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.671 0.329 0.000
T00-T07 Injuries involving multiple body regions
0.671 0.329 0.000
S90-S99 Injuries to the ankle and foot
0.671 0.329 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.671 0.329 0.000
S20-S29 Injuries to the thorax
0.671 0.329 0.000
S10-S19 Injuries to the neck
0.671 0.329 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.671 0.329 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.667 0.333 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.666 0.333 0.000
K20 Oesophagitis
0.666 0.334 0.000
S70-S79 Injuries to the hip and thigh
0.666 0.334 0.000
K29.7 Gastritis, unspecified
0.665 0.335 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.664 0.336 0.000
K55 Vascular disorders of intestine
0.664 0.336 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.664 0.336 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.664 0.336 0.000
H53-H54 Visual disturbances and blindness
0.663 0.337 0.000
S00-S09 Injuries to the head
0.661 0.339 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.661 0.339 0.000
Z95.4 Presence of other heart-valve replacement
0.661 0.339 0.000
Z95.3 Presence of xenogenic heart valve
0.661 0.339 0.000
Z95.2 Presence of prosthetic heart valve
0.661 0.339 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.660 0.340 0.000
N84 Polyp of female genital tract
0.659 0.341 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.659 0.341 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.656 0.344 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.655 0.345 0.000
I30-I52 Other forms of heart disease
0.654 0.346 0.000
M50-M54 Other dorsopathies
0.652 0.347 0.000
M80-M85 Disorders of bone density and structure
0.652 0.348 0.000
Chapter V Mental and behavioural disorders
0.652 0.348 0.000
K59.0 Constipation
0.651 0.349 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.651 0.349 0.000
M06 Other rheumatoid arthritis
0.650 0.350 0.000
W00-W19 Falls
0.648 0.352 0.000
N39.3 Stress incontinence
0.648 0.352 0.000
I60-I69 Cerebrovascular diseases
0.647 0.353 0.000
M25.5 Pain in joint
0.645 0.355 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.644 0.356 0.000
K76 Other diseases of liver
0.643 0.357 0.000
N93 Other abnormal uterine and vaginal bleeding
0.641 0.359 0.000
Z93.6 Other artificial openings of urinary tract status
0.640 0.360 0.000
M17 Gonarthrosis [arthrosis of knee]
0.639 0.361 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.638 0.362 0.000
K60 Fissure and fistula of anal and rectal regions
0.638 0.362 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.638 0.362 0.000
S68 Traumatic amputation of wrist and hand
0.637 0.363 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.637 0.363 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.637 0.363 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.637 0.363 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.637 0.363 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.637 0.363 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.637 0.363 0.000
Y35-Y36 Legal intervention and operations of war
0.637 0.363 0.000
Y10-Y34 Event of undetermined intent
0.637 0.363 0.000
Y00-Y09 Assault
0.637 0.363 0.000
X85-X99 Assault
0.637 0.363 0.000
X60-X84 Intentional self-harm
0.637 0.363 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.637 0.363 0.000
X50-X57 Overexertion, travel and privation
0.637 0.363 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.637 0.363 0.000
X30-X39 Exposure to forces of nature
0.637 0.363 0.000
X20-X29 Contact with venomous animals and plants
0.637 0.363 0.000
X10-X19 Contact with heat and hot substances
0.637 0.363 0.000
X00-X09 Exposure to smoke, fire and flames
0.637 0.363 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.637 0.363 0.000
W75-W84 Other accidental threats to breathing
0.637 0.363 0.000
W65-W74 Accidental drowning and submersion
0.637 0.363 0.000
W50-W64 Exposure to animate mechanical forces
0.637 0.363 0.000
W20-W49 Exposure to inanimate mechanical forces
0.637 0.363 0.000
V98-V99 Other and unspecified transport accidents
0.637 0.363 0.000
V95-V97 Air and space transport accidents
0.637 0.363 0.000
V90-V94 Water transport accidents
0.637 0.363 0.000
V80-V89 Other land transport accidents
0.637 0.363 0.000
V70-V79 Bus occupant injured in transport accident
0.637 0.363 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.637 0.363 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.637 0.363 0.000
V40-V49 Car occupant injured in transport accident
0.637 0.363 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.637 0.363 0.000
V20-V29 Motorcycle rider injured in transport accident
0.637 0.363 0.000
V10-V19 Pedal cyclist injured in transport accident
0.637 0.363 0.000
V01-V09 Pedestrian injured in transport accident
0.637 0.363 0.000
H30-H36 Disorders of choroid and retina
0.636 0.363 0.000
I21.4 Acute subendocardial myocardial infarction
0.636 0.364 0.000
K90 Intestinal malabsorption
0.635 0.364 0.000
I20.8 Other forms of angina pectoris
0.635 0.365 0.000
I20.1 Angina pectoris with documented spasm
0.635 0.365 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.634 0.366 0.000
M13 Other arthritis
0.633 0.367 0.000
M35 Other systemic involvement of connective tissue
0.633 0.367 0.000
N13 Obstructive and reflux uropathy
0.632 0.368 0.000
I78 Diseases of capillaries
0.632 0.368 0.000
K70 Alcoholic liver disease
0.631 0.369 0.000
K30 Dyspepsia
0.631 0.369 0.000
H55-H59 Other disorders of eye and adnexa
0.630 0.370 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.630 0.370 0.000
H43-H45 Disorders of vitreous body and globe
0.630 0.370 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.630 0.370 0.000
H10-H13 Disorders of conjunctiva
0.630 0.370 0.000
K22.7 Barrett's oesophagus
0.630 0.370 0.000
Z96 Presence of other functional implants
0.629 0.370 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.629 0.371 0.000
I73 Other peripheral vascular diseases
0.629 0.371 0.000
N92 Excessive, frequent and irregular menstruation
0.626 0.374 0.000
Z34 Supervision of normal pregnancy
0.626 0.374 0.000
N37 Urethral disorders in diseases classified elsewhere
0.625 0.375 0.000
N36 Other disorders of urethra
0.625 0.375 0.000
N34 Urethritis and urethral syndrome
0.625 0.375 0.000
N33 Bladder disorders in diseases classified elsewhere
0.625 0.375 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.625 0.375 0.000
Y83.4 Other reconstructive surgery
0.625 0.375 0.000
C15-C26 Malignant neoplasms of digestive organs
0.625 0.375 0.000
N32 Other disorders of bladder
0.623 0.376 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.622 0.378 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.618 0.382 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.615 0.385 0.000
N86 Erosion and ectropion of cervix uteri
0.614 0.385 0.000
M75 Shoulder lesions
0.613 0.386 0.000
Chapter I Certain infectious and parasitic diseases
0.613 0.386 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.613 0.387 0.000
M18 Arthrosis of first carpometacarpal joint
0.613 0.387 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.613 0.387 0.000
M34 Systemic sclerosis
0.613 0.387 0.000
M33 Dermatopolymyositis
0.613 0.387 0.000
M32 Systemic lupus erythematosus
0.613 0.387 0.000
M31 Other necrotising vasculopathies
0.613 0.387 0.000
M30 Polyarteritis nodosa and related conditions
0.613 0.387 0.000
M24 Other specific joint derangements
0.613 0.387 0.000
M22 Disorders of patella
0.613 0.387 0.000
M21 Other acquired deformities of limbs
0.613 0.387 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.612 0.388 0.000
I20.0 Unstable angina
0.610 0.390 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.609 0.391 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.609 0.391 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.609 0.391 0.000
K26.7 Chronic without haemorrhage or perforation
0.606 0.393 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.606 0.393 0.000
K26.5 Chronic or unspecified with perforation
0.606 0.393 0.000
K26.4 Chronic or unspecified with haemorrhage
0.606 0.393 0.000
K26.3 Acute without haemorrhage or perforation
0.606 0.393 0.000
K26.2 Acute with both haemorrhage and perforation
0.606 0.393 0.000
K26.1 Acute with perforation
0.606 0.393 0.000
K26.0 Acute with haemorrhage
0.606 0.393 0.000
I71 Aortic aneurysm and dissection
0.606 0.394 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.606 0.394 0.000
E10-E14 Diabetes mellitus
0.605 0.395 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.604 0.396 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.604 0.396 0.000
M25.7 Osteophyte
0.604 0.396 0.000
H40-H42 Glaucoma
0.601 0.399 0.000
M20.2 Hallux rigidus
0.600 0.400 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.596 0.404 0.000
K56.6 Other and unspecified intestinal obstruction
0.595 0.404 0.000
S52 Fracture of forearm
0.595 0.405 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.595 0.405 0.000
Z98 Other postsurgical states
0.594 0.405 0.000
C50-C50 Malignant neoplasm of breast
0.594 0.406 0.000
K43 Ventral hernia
0.594 0.406 0.000
K25.7 Chronic without haemorrhage or perforation
0.593 0.406 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.593 0.406 0.000
K25.5 Chronic or unspecified with perforation
0.593 0.406 0.000
K25.4 Chronic or unspecified with haemorrhage
0.593 0.406 0.000
K25.3 Acute without haemorrhage or perforation
0.593 0.406 0.000
K25.2 Acute with both haemorrhage and perforation
0.593 0.406 0.000
K25.1 Acute with perforation
0.593 0.406 0.000
K25.0 Acute with haemorrhage
0.593 0.406 0.000
D23 Other benign neoplasms of skin
0.592 0.408 0.000
K31.7 Polyp of stomach and duodenum
0.591 0.409 0.000
M20.1 Hallux valgus (acquired)
0.590 0.410 0.000
C64-C68 Malignant neoplasms of urinary tract
0.590 0.410 0.000
N89 Other noninflammatory disorders of vagina
0.589 0.411 0.000
Y83.6 Removal of other organ (partial) (total)
0.588 0.412 0.000
R10 Abdominal and pelvic pain
0.588 0.412 0.000
K42 Umbilical hernia
0.587 0.413 0.000
S42 Fracture of shoulder and upper arm
0.586 0.414 0.000
K22.9 Disease of oesophagus, unspecified
0.585 0.415 0.000
K22.8 Other specified diseases of oesophagus
0.585 0.415 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.585 0.415 0.000
K22.5 Diverticulum of oesophagus, acquired
0.585 0.415 0.000
K22.4 Dyskinesia of oesophagus
0.585 0.415 0.000
K22.3 Perforation of oesophagus
0.585 0.415 0.000
K22.0 Achalasia of cardia
0.585 0.415 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.584 0.416 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.584 0.416 0.000
I77 Other disorders of arteries and arterioles
0.584 0.416 0.000
I74 Arterial embolism and thrombosis
0.584 0.416 0.000
I72 Other aneurysm
0.584 0.416 0.000
I70 Atherosclerosis
0.584 0.416 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.584 0.416 0.000
E70-E90 Metabolic disorders
0.583 0.416 0.000
E03 Other hypothyroidism
0.583 0.417 0.000
G20-G26 Extrapyramidal and movement disorders
0.583 0.417 0.000
K77 Liver disorders in diseases classified elsewhere
0.582 0.417 0.000
K75 Other inflammatory liver diseases
0.582 0.417 0.000
K74 Fibrosis and cirrhosis of liver
0.582 0.417 0.000
K73 Chronic hepatitis, not elsewhere classified
0.582 0.417 0.000
K72 Hepatic failure, not elsewhere classified
0.582 0.417 0.000
K71 Toxic liver disease
0.582 0.417 0.000
I24.8 Other forms of acute ischaemic heart disease
0.582 0.418 0.000
N39.9 Disorder of urinary system, unspecified
0.581 0.419 0.000
N39.8 Other specified disorders of urinary system
0.581 0.419 0.000
N39.2 Orthostatic proteinuria, unspecified
0.581 0.419 0.000
N39.1 Persistent proteinuria, unspecified
0.581 0.419 0.000
N98 Complications associated with artificial fertilisation
0.581 0.419 0.000
N97 Female infertility
0.581 0.419 0.000
N91 Absent, scanty and rare menstruation
0.581 0.419 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.581 0.419 0.000
N88 Other noninflammatory disorders of cervix uteri
0.581 0.419 0.000
N87 Dysplasia of cervix uteri
0.581 0.419 0.000
N82 Fistulae involving female genital tract
0.581 0.419 0.000
N96 Habitual aborter
0.581 0.419 0.000
M16 Coxarthrosis [arthrosis of hip]
0.580 0.419 0.000
K92.0 Haematemesis
0.580 0.420 0.000
Z37 Outcome of delivery
0.580 0.420 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.580 0.420 0.000
K61.0 Anal abscess
0.579 0.420 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.579 0.421 0.000
D00-D09 In situ neoplasms
0.579 0.421 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.579 0.421 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.579 0.421 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.579 0.421 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.579 0.421 0.000
C51-C58 Malignant neoplasms of female genital organs
0.579 0.421 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.579 0.421 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.579 0.421 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.579 0.421 0.000
G90-G99 Other disorders of the nervous system
0.578 0.422 0.000
S61 Open wound of wrist and hand
0.578 0.422 0.000
Z93.3 Colostomy status
0.578 0.422 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.577 0.423 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.577 0.423 0.000
E50-E64 Other nutritional deficiencies
0.574 0.426 0.000
E40-E46 Malnutrition
0.574 0.426 0.000
E20-E35 Disorders of other endocrine glands
0.574 0.426 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.574 0.426 0.000
R10.4 Other and unspecified abdominal pain
0.574 0.426 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.572 0.428 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.572 0.428 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.572 0.428 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.572 0.428 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.572 0.428 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.572 0.428 0.000
M14 Arthropathies in other diseases classified elsewhere
0.571 0.429 0.000
M12 Other specific arthropathies
0.571 0.429 0.000
M11 Other crystal arthropathies
0.571 0.429 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.571 0.429 0.000
M08 Juvenile arthritis
0.571 0.429 0.000
M07 Psoriatic and enteropathic arthropathies
0.571 0.429 0.000
M05 Seropositive rheumatoid arthritis
0.571 0.429 0.000
Z60 Problems related to social environment
0.571 0.429 0.000
N95 Menopausal and other perimenopausal disorders
0.570 0.430 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.568 0.432 0.000
T87 Complications peculiar to reattachment and amputation
0.568 0.432 0.000
T86 Failure and rejection of transplanted organs and tissues
0.568 0.432 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.568 0.432 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.568 0.432 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.568 0.432 0.000
N39.4 Other specified urinary incontinence
0.566 0.434 0.000
G70-G73 Diseases of myoneural junction and muscle
0.565 0.434 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.565 0.434 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.565 0.434 0.000
G30-G32 Other degenerative diseases of the nervous system
0.565 0.434 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.565 0.434 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.565 0.434 0.000
N19 Unspecified renal failure
0.564 0.435 0.000
M23 Internal derangement of knee
0.564 0.436 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.563 0.437 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.563 0.437 0.000
N21 Calculus of lower urinary tract
0.563 0.437 0.000
K63.3 Ulcer of intestine
0.563 0.437 0.000
N20.1 Calculus of ureter
0.562 0.438 0.000
M15 Polyarthrosis
0.559 0.440 0.000
Z93.9 Artificial opening status, unspecified
0.558 0.442 0.000
Z93.8 Other artificial opening status
0.558 0.442 0.000
Z93.5 Cystostomy status
0.558 0.442 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.558 0.442 0.000
Z93.2 Ileostomy status
0.558 0.442 0.000
Z93.1 Gastrostomy status
0.558 0.442 0.000
Z93.0 Tracheostomy status
0.558 0.442 0.000
K62 Other diseases of anus and rectum
0.557 0.443 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.557 0.443 0.000
M10 Gout
0.556 0.444 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.556 0.444 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.556 0.444 0.000
H27 Other disorders of lens
0.556 0.444 0.000
K50 Crohn's disease [regional enteritis]
0.555 0.445 0.000
Z39 Postpartum care and examination
0.553 0.447 0.000
Z38 Liveborn infants according to place of birth
0.553 0.447 0.000
Z36 Antenatal screening
0.553 0.447 0.000
Z35 Supervision of high-risk pregnancy
0.553 0.447 0.000
Z32 Pregnancy examination and test
0.553 0.447 0.000
Z31 Procreative management
0.553 0.447 0.000
Z33 Pregnant state, incidental
0.553 0.447 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.553 0.447 0.000
N15 Other renal tubulo-interstitial diseases
0.553 0.447 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.553 0.447 0.000
N11 Chronic tubulo-interstitial nephritis
0.553 0.447 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.553 0.447 0.000
N10 Acute tubulo-interstitial nephritis
0.553 0.447 0.000
N80 Endometriosis
0.553 0.447 0.000
S69 Other and unspecified injuries of wrist and hand
0.553 0.447 0.000
S67 Crushing injury of wrist and hand
0.553 0.447 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.553 0.447 0.000
S65 Injury of blood vessels at wrist and hand level
0.553 0.447 0.000
S64 Injury of nerves at wrist and hand level
0.553 0.447 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.553 0.447 0.000
S62 Fracture at wrist and hand level
0.553 0.447 0.000
S60 Superficial injury of wrist and hand
0.553 0.447 0.000
K51 Ulcerative colitis
0.552 0.447 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.552 0.448 0.000
N18 Chronic renal failure
0.552 0.448 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.552 0.448 0.000
G56 Mononeuropathies of upper limb
0.550 0.450 0.000
H80-H83 Diseases of inner ear
0.550 0.450 0.000
K59.9 Functional intestinal disorder, unspecified
0.549 0.451 0.000
K59.8 Other specified functional intestinal disorders
0.549 0.451 0.000
K59.4 Anal spasm
0.549 0.451 0.000
K59.3 Megacolon, not elsewhere classified
0.549 0.451 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.549 0.451 0.000
K59.1 Functional diarrhoea
0.549 0.451 0.000
N17 Acute renal failure
0.549 0.451 0.000
N40-N51 Diseases of male genital organs
0.547 0.453 0.000
K13 Other diseases of lip and oral mucosa
0.546 0.454 0.000
M06.9 Rheumatoid arthritis, unspecified
0.546 0.454 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.546 0.454 0.000
K63.5 Polyp of colon
0.546 0.454 0.000
N35 Urethral stricture
0.543 0.456 0.000
M17.1 Other primary gonarthrosis
0.543 0.457 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.542 0.458 0.000
I24.1 Dressler's syndrome
0.542 0.458 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.542 0.458 0.000
N20.0 Calculus of kidney
0.542 0.458 0.000
M65 Synovitis and tenosynovitis
0.542 0.458 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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