TreeWAS – Variant ID: rs117071818

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000
G40-G47 Episodic and paroxysmal disorders	0.999	0.001
E70-E90 Metabolic disorders	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
E10-E14 Diabetes mellitus	0.997	0.003
J40-J47 Chronic lower respiratory diseases	0.996	0.004
Chapter II Neoplasms	0.995	0.005
E87 Other disorders of fluid, electrolyte and acid-base balance	0.993	0.007
Chapter V Mental and behavioural disorders	0.993	0.007
Chapter XIV Diseases of the genitourinary system	0.990	0.010
N17-N19 Renal failure	0.988	0.012
M70-M79 Other soft tissue disorders	0.987	0.013
E10 Insulin-dependent diabetes mellitus	0.987	0.013
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.987	0.013
G45 Transient cerebral ischaemic attacks and related syndromes	0.985	0.015
G47 Sleep disorders	0.984	0.016
N18 Chronic renal failure	0.984	0.016
I30-I52 Other forms of heart disease	0.981	0.019
J44 Other chronic obstructive pulmonary disease	0.979	0.021
Chapter VIII Diseases of the ear and mastoid process	0.974	0.026
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.970	0.030
Chapter XXI Factors influencing health status and contact with health services	0.967	0.033
G45.9 Transient cerebral ischaemic attack, unspecified	0.963	0.037
N18.9 Chronic renal failure, unspecified	0.963	0.037
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.962	0.038
M20-M25 Other joint disorders	0.962	0.038
F30-F39 Mood [affective] disorders	0.957	0.043
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.956	0.044
G47.3 Sleep apnoea	0.955	0.045
J95-J99 Other diseases of the respiratory system	0.952	0.048
I70-I79 Diseases of arteries, arterioles and capillaries	0.952	0.048
M75 Shoulder lesions	0.951	0.049
I26 Pulmonary embolism	0.950	0.050
S60-S69 Injuries to the wrist and hand	0.944	0.056
C79 Secondary malignant neoplasm of other sites	0.944	0.056
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.943	0.057
T36-T50 Poisoning by drugs, medicaments and biological substances	0.943	0.057
N17 Acute renal failure	0.942	0.058
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.939	0.061
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.938	0.062
E10.9 Without complications	0.938	0.062
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.935	0.065
F32 Depressive episode	0.930	0.070
Z86 Personal history of certain other diseases	0.930	0.070
E87.1 Hypo-osmolality and hyponatraemia	0.928	0.072
H90-H95 Other disorders of ear	0.927	0.073
M79 Other soft tissue disorders, not elsewhere classified	0.927	0.073
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.926	0.074
I34 Nonrheumatic mitral valve disorders	0.920	0.080
M05-M14 Inflammatory polyarthropathies	0.917	0.083
I84 Haemorrhoids	0.916	0.084
I10-I15 Hypertensive diseases	0.915	0.085
Z86.4 Personal history of psychoactive substance abuse	0.914	0.086
E11 Non-insulin-dependent diabetes mellitus	0.911	0.089
N17.9 Acute renal failure, unspecified	0.909	0.091
J44.9 Chronic obstructive pulmonary disease, unspecified	0.904	0.096
D37-D48 Neoplasms of uncertain or unknown behaviour	0.902	0.098
Chapter I Certain infectious and parasitic diseases	0.902	0.098
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.901	0.099
M31 Other necrotising vasculopathies	0.900	0.100
J80-J84 Other respiratory diseases principally affecting the interstitium	0.900	0.100
I95-I99 Other and unspecified disorders of the circulatory system	0.899	0.101
J09-J18 Influenza and pneumonia	0.898	0.102
J43 Emphysema	0.895	0.105
J46 Status asthmaticus	0.893	0.107
J98 Other respiratory disorders	0.892	0.108
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.891	0.109
M75.0 Adhesive capsulitis of shoulder	0.891	0.109
M45-M49 Spondylopathies	0.890	0.110
Z88.6 Personal history of allergy to analgesic agent	0.886	0.114
J90-J94 Other diseases of pleura	0.885	0.115
E86 Volume depletion	0.885	0.115
I84.5 External haemorrhoids without complication	0.884	0.116
M15-M19 Arthrosis	0.883	0.117
I60-I69 Cerebrovascular diseases	0.882	0.118
M79.0 Rheumatism, unspecified	0.880	0.120
I12 Hypertensive renal disease	0.877	0.123
F32.9 Depressive episode, unspecified	0.877	0.123
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.875	0.125
N00-N08 Glomerular diseases	0.875	0.125
F00-F09 Organic, including symptomatic, mental disorders	0.873	0.127
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.871	0.129
F40-F48 Neurotic, stress-related and somatoform disorders	0.871	0.129
I05-I09 Chronic rheumatic heart diseases	0.869	0.131
E20-E35 Disorders of other endocrine glands	0.868	0.132
M25 Other joint disorders, not elsewhere classified	0.868	0.132
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.868	0.132
Z99.2 Dependence on renal dialysis	0.860	0.140
E87.3 Alkalosis	0.854	0.146
S61 Open wound of wrist and hand	0.852	0.148
I12.0 Hypertensive renal disease with renal failure	0.852	0.148
E78.0 Pure hypercholesterolaemia	0.849	0.151
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.848	0.152
S20-S29 Injuries to the thorax	0.847	0.153
E50-E64 Other nutritional deficiencies	0.847	0.153
B95-B98 Bacterial, viral and other infectious agents	0.844	0.156
E10.4 With neurological complications	0.843	0.157
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.843	0.157
G43 Migraine	0.843	0.157
Chapter XV Pregnancy, childbirth and the puerperium	0.842	0.158
G44 Other headache syndromes	0.840	0.160
H90 Conductive and sensorineural hearing loss	0.839	0.161
J20-J22 Other acute lower respiratory infections	0.839	0.161
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.836	0.164
I34.0 Mitral (valve) insufficiency	0.836	0.164
I84.8 Unspecified haemorrhoids with other complications	0.835	0.165
N20-N23 Urolithiasis	0.833	0.167
I95 Hypotension	0.833	0.167
G47.9 Sleep disorder, unspecified	0.831	0.169
N18.5 Chronic kidney disease, stage 5	0.828	0.172
I73 Other peripheral vascular diseases	0.828	0.172
I44 Atrioventricular and left bundle-branch block	0.827	0.173
C78.0 Secondary malignant neoplasm of lung	0.827	0.173
C64-C68 Malignant neoplasms of urinary tract	0.826	0.174
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.826	0.174
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.825	0.175
M80-M85 Disorders of bone density and structure	0.824	0.176
J43.9 Emphysema, unspecified	0.823	0.176
H80-H83 Diseases of inner ear	0.823	0.177
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.822	0.178
E87.7 Fluid overload	0.820	0.180
J18 Pneumonia, organism unspecified	0.820	0.180
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.817	0.182
E10.3 With ophthalmic complications	0.817	0.183
E10.5 With peripheral circulatory complications	0.815	0.185
G45.4 Transient global amnesia	0.814	0.186
G50-G59 Nerve, nerve root and plexus disorders	0.814	0.186
J98.4 Other disorders of lung	0.814	0.186
Z86.5 Personal history of other mental and behavioural disorders	0.813	0.187
E87.2 Acidosis	0.812	0.188
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.810	0.190
J60-J70 Lung diseases due to external agents	0.810	0.190
Z91 Personal history of risk-factors, not elsewhere classified	0.809	0.191
M06 Other rheumatoid arthritis	0.808	0.192
M23 Internal derangement of knee	0.807	0.193
M86-M90 Other osteopathies	0.807	0.193
G80-G83 Cerebral palsy and other paralytic syndromes	0.806	0.194
Z70-Z76 Persons encountering health services in other circumstances	0.805	0.195
N18.0 End-stage renal disease	0.802	0.198
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.800	0.200
J95 Postprocedural respiratory disorders, not elsewhere classified	0.800	0.200
I35 Nonrheumatic aortic valve disorders	0.800	0.200
N25-N29 Other disorders of kidney and ureter	0.799	0.201
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.799	0.201
M75.4 Impingement syndrome of shoulder	0.798	0.202
Z88.5 Personal history of allergy to narcotic agent	0.797	0.203
M31.3 Wegener's granulomatosis	0.797	0.203
E10.1 With ketoacidosis	0.796	0.204
J44.8 Other specified chronic obstructive pulmonary disease	0.795	0.205
J40 Bronchitis, not specified as acute or chronic	0.795	0.205
I78 Diseases of capillaries	0.795	0.205
N18.4 Chronic kidney disease, stage 4	0.795	0.205
M79.09 Rheumatism, unspecified (Site unspecified)	0.795	0.205
S66 Injury of muscle and tendon at wrist and hand level	0.794	0.206
G47.1 Disorders of excessive somnolence [hypersomnias]	0.793	0.207
E13 Other specified diabetes mellitus	0.793	0.207
M47 Spondylosis	0.793	0.207
G70-G73 Diseases of myoneural junction and muscle	0.793	0.207
I50 Heart failure	0.792	0.208
H60-H62 Diseases of external ear	0.792	0.208
D60-D64 Aplastic and other anaemias	0.792	0.208
H91 Other hearing loss	0.791	0.209
I61 Intracerebral haemorrhage	0.790	0.210
M31.6 Other giant cell arteritis	0.790	0.210
I51 Complications and ill-defined descriptions of heart disease	0.790	0.210
S61.8 Open wound of other parts of wrist and hand	0.790	0.210
Z86.6 Personal history of diseases of the nervous system and sense organs	0.789	0.211
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.788	0.212
I33 Acute and subacute endocarditis	0.787	0.213
N18.3 Chronic kidney disease, stage 3	0.787	0.213
I34.1 Mitral (valve) prolapse	0.786	0.214
I74 Arterial embolism and thrombosis	0.785	0.215
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.785	0.215
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.785	0.215
N10-N16 Renal tubulo-interstitial diseases	0.782	0.218
E11.4 With neurological complications	0.782	0.218
M79.00 Rheumatism, unspecified (Multiple sites)	0.782	0.218
J84 Other interstitial pulmonary diseases	0.781	0.219
M10 Gout	0.779	0.221
G45.3 Amaurosis fugax	0.778	0.222
Z88.0 Personal history of allergy to penicillin	0.778	0.222
C45 Mesothelioma	0.777	0.223
Z89 Acquired absence of limb	0.776	0.224
E11.2 With renal complications	0.775	0.225
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.774	0.226
C80 Malignant neoplasm without specification of site	0.773	0.227
I73.9 Peripheral vascular disease, unspecified	0.772	0.228
E87.5 Hyperkalaemia	0.772	0.228
I95.9 Hypotension, unspecified	0.772	0.228
H90.5 Sensorineural hearing loss, unspecified	0.772	0.228
F32.2 Severe depressive episode without psychotic symptoms	0.772	0.228
J42 Unspecified chronic bronchitis	0.769	0.231
D00-D09 In situ neoplasms	0.767	0.233
E78.2 Mixed hyperlipidaemia	0.767	0.233
E80 Disorders of porphyrin and bilirubin metabolism	0.766	0.234
M25.4 Effusion of joint	0.765	0.235
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.764	0.236
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.763	0.237
M77 Other enthesopathies	0.763	0.237
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.763	0.237
S90-S99 Injuries to the ankle and foot	0.761	0.239
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.761	0.239
O60-O75 Complications of labour and delivery	0.761	0.239
Z99.1 Dependence on respirator	0.760	0.240
N23 Unspecified renal colic	0.760	0.240
E11.5 With peripheral circulatory complications	0.760	0.240
F33 Recurrent depressive disorder	0.759	0.241
M19 Other arthrosis	0.756	0.244
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.755	0.245
C79.9 Secondary malignant neoplasm, unspecified site	0.753	0.247
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.751	0.249
Z81 Family history of mental and behavioural disorders	0.750	0.250
I87 Other disorders of veins	0.749	0.251
Chapter XXII Codes for special purposes	0.749	0.251
C79.2 Secondary malignant neoplasm of skin	0.748	0.252
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.747	0.253
H81 Disorders of vestibular function	0.746	0.254
J81 Pulmonary oedema	0.745	0.255
C79.7 Secondary malignant neoplasm of adrenal gland	0.745	0.255
M65-M68 Disorders of synovium and tendon	0.744	0.256
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.744	0.256
S67 Crushing injury of wrist and hand	0.744	0.256
E87.0 Hyperosmolality and hypernatraemia	0.743	0.257
F32.1 Moderate depressive episode	0.743	0.257
Z99.3 Dependence on wheelchair	0.742	0.258
F03 Unspecified dementia	0.742	0.258
D64 Other anaemias	0.742	0.258
D45 Polycythaemia vera	0.740	0.260
I44.7 Left bundle-branch block, unspecified	0.740	0.260
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.740	0.260
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.739	0.261
R50-R69 General symptoms and signs	0.739	0.261
C01 Malignant neoplasm of base of tongue	0.739	0.261
T66-T78 Other and unspecified effects of external causes	0.738	0.262
G30-G32 Other degenerative diseases of the nervous system	0.738	0.262
I47 Paroxysmal tachycardia	0.738	0.262
M16 Coxarthrosis [arthrosis of hip]	0.737	0.263
E78.5 Hyperlipidaemia, unspecified	0.737	0.263
J93 Pneumothorax	0.736	0.264
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.735	0.265
F80-F89 Disorders of psychological development	0.734	0.265
M05 Seropositive rheumatoid arthritis	0.734	0.266
T15-T19 Effects of foreign body entering through natural orifice	0.733	0.267
C79.8 Secondary malignant neoplasm of other specified sites	0.733	0.267
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.733	0.267
S80-S89 Injuries to the knee and lower leg	0.733	0.267
J18.9 Pneumonia, unspecified	0.733	0.267
H93 Other disorders of ear, not elsewhere classified	0.732	0.267
M23.3 Other meniscus derangements	0.732	0.268
G90-G99 Other disorders of the nervous system	0.731	0.269
M40-M43 Deforming dorsopathies	0.730	0.270
Z96 Presence of other functional implants	0.729	0.271
J98.1 Pulmonary collapse	0.729	0.271
I80 Phlebitis and thrombophlebitis	0.726	0.274
I71 Aortic aneurysm and dissection	0.726	0.274
I05 Rheumatic mitral valve diseases	0.725	0.274
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.725	0.274
G44.2 Tension-type headache	0.725	0.275
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.725	0.275
M35 Other systemic involvement of connective tissue	0.725	0.275
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.725	0.275
I61.9 Intracerebral haemorrhage, unspecified	0.725	0.275
M79.1 Myalgia	0.724	0.276
J22 Unspecified acute lower respiratory infection	0.724	0.276
F43 Reaction to severe stress, and adjustment disorders	0.723	0.277
Z94 Transplanted organ and tissue status	0.723	0.277
I35.1 Aortic (valve) insufficiency	0.722	0.278
I46 Cardiac arrest	0.722	0.278
S40-S49 Injuries to the shoulder and upper arm	0.722	0.278
M25.7 Osteophyte	0.718	0.282
C51-C58 Malignant neoplasms of female genital organs	0.718	0.282
N02 Recurrent and persistent haematuria	0.718	0.282
E40-E46 Malnutrition	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
M24 Other specific joint derangements	0.717	0.283
G00-G09 Inflammatory diseases of the central nervous system	0.717	0.283
G46 Vascular syndromes of brain in cerebrovascular diseases	0.716	0.283
G41 Status epilepticus	0.716	0.283
S60 Superficial injury of wrist and hand	0.716	0.283
E88 Other metabolic disorders	0.716	0.284
E85 Amyloidosis	0.716	0.284
E84 Cystic fibrosis	0.716	0.284
E79 Disorders of purine and pyrimidine metabolism	0.716	0.284
E77 Disorders of glycoprotein metabolism	0.716	0.284
E76 Disorders of glycosaminoglycan metabolism	0.716	0.284
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.716	0.284
E74 Other disorders of carbohydrate metabolism	0.716	0.284
E73 Lactose intolerance	0.716	0.284
E72 Other disorders of amino-acid metabolism	0.716	0.284
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.716	0.284
E70 Disorders of aromatic amino-acid metabolism	0.716	0.284
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.716	0.284
C77.0 Lymph nodes of head, face and neck	0.716	0.284
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.716	0.284
T79-T79 Certain early complications of trauma	0.715	0.284
T33-T35 Frostbite	0.715	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.284
T00-T07 Injuries involving multiple body regions	0.715	0.284
S10-S19 Injuries to the neck	0.715	0.284
A30-A49 Other bacterial diseases	0.715	0.285
E12 Malnutrition-related diabetes mellitus	0.715	0.285
M75.2 Bicipital tendinitis	0.714	0.286
J41 Simple and mucopurulent chronic bronchitis	0.714	0.286
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
E87.4 Mixed disorder of acid-base balance	0.712	0.288
F99-F99 Unspecified mental disorder	0.712	0.288
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.712	0.288
F70-F79 Mental retardation	0.712	0.288
F60-F69 Disorders of adult personality and behaviour	0.712	0.288
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.712	0.288
S70-S79 Injuries to the hip and thigh	0.712	0.288
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.710	0.289
I08 Multiple valve diseases	0.709	0.291
M75.1 Rotator cuff syndrome	0.709	0.291
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.709	0.291
M76 Enthesopathies of lower limb, excluding foot	0.708	0.292
M73 Soft tissue disorders in diseases classified elsewhere	0.708	0.292
M71 Other bursopathies	0.708	0.292
E10.8 With unspecified complications	0.708	0.292
E10.7 With multiple complications	0.708	0.292
E10.6 With other specified complications	0.708	0.292
E10.2 With renal complications	0.708	0.292
E10.0 With coma	0.708	0.292
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.708	0.292
C76 Malignant neoplasm of other and ill-defined sites	0.708	0.292
F32.3 Severe depressive episode with psychotic symptoms	0.707	0.293
N08 Glomerular disorders in diseases classified elsewhere	0.707	0.293
Z97 Presence of other devices	0.707	0.293
E87.6 Hypokalaemia	0.707	0.293
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.706	0.294
G45.2 Multiple and bilateral precerebral artery syndromes	0.706	0.294
G45.1 Carotid artery syndrome (hemispheric)	0.706	0.294
G45.0 Vertebro-basilar artery syndrome	0.706	0.294
D64.9 Anaemia, unspecified	0.706	0.294
M46 Other inflammatory spondylopathies	0.706	0.294
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.706	0.294
J00-J06 Acute upper respiratory infections	0.706	0.294
G47.8 Other sleep disorders	0.705	0.294
G47.4 Narcolepsy and cataplexy	0.705	0.294
G47.2 Disorders of the sleep-wake schedule	0.705	0.294
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.705	0.294
R51 Headache	0.705	0.295
N18.8 Other chronic renal failure	0.705	0.295
N18.2 Chronic kidney disease, stage 2	0.705	0.295
N18.1 Chronic kidney disease, stage 1	0.705	0.295
J47 Bronchiectasis	0.705	0.295
S32 Fracture of lumbar spine and pelvis	0.704	0.296
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.704	0.296
I52 Other heart disorders in diseases classified elsewhere	0.704	0.296
I48 Atrial fibrillation and flutter	0.704	0.296
I43 Cardiomyopathy in diseases classified elsewhere	0.704	0.296
I41 Myocarditis in diseases classified elsewhere	0.704	0.296
I40 Acute myocarditis	0.704	0.296
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.704	0.296
I37 Pulmonary valve disorders	0.704	0.296
I36 Nonrheumatic tricuspid valve disorders	0.704	0.296
I32 Pericarditis in diseases classified elsewhere	0.704	0.296
I30 Acute pericarditis	0.704	0.296
M70 Soft tissue disorders related to use, overuse and pressure	0.703	0.297
I64 Stroke, not specified as haemorrhage or infarction	0.703	0.297
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.703	0.297
C78.2 Secondary malignant neoplasm of pleura	0.701	0.298
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.701	0.299
I49 Other cardiac arrhythmias	0.701	0.299
J91 Pleural effusion in conditions classified elsewhere	0.700	0.300
E53 Deficiency of other B group vitamins	0.700	0.300
C67 Malignant neoplasm of bladder	0.700	0.300
F01 Vascular dementia	0.699	0.301
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.699	0.301
H81.0 Meniere's disease	0.698	0.302
G43.1 Migraine with aura [classical migraine]	0.697	0.303
S64 Injury of nerves at wrist and hand level	0.697	0.303
M79.8 Other specified soft tissue disorders	0.697	0.303
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.697	0.303
J84.1 Other interstitial pulmonary diseases with fibrosis	0.696	0.304
Q60-Q64 Congenital malformations of the urinary system	0.696	0.304
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.696	0.304
I28 Other diseases of pulmonary vessels	0.696	0.304
M45 Ankylosing spondylitis	0.696	0.304
M18 Arthrosis of first carpometacarpal joint	0.696	0.304
H91.9 Hearing loss, unspecified	0.693	0.307
G63 Polyneuropathy in diseases classified elsewhere	0.693	0.307
Z99.8 Dependence on other enabling machines and devices	0.693	0.307
I70 Atherosclerosis	0.693	0.307
I77 Other disorders of arteries and arterioles	0.690	0.310
J95.8 Other postprocedural respiratory disorders	0.690	0.310
Z84 Family history of other conditions	0.690	0.310
Z83 Family history of other specific disorders	0.690	0.310
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.690	0.310
M34 Systemic sclerosis	0.690	0.310
M33 Dermatopolymyositis	0.690	0.310
M32 Systemic lupus erythematosus	0.690	0.310
M30 Polyarteritis nodosa and related conditions	0.690	0.310
C60-C63 Malignant neoplasms of male genital organs	0.689	0.310
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.689	0.311
F45 Somatoform disorders	0.688	0.312
I27 Other pulmonary heart diseases	0.688	0.312
M21 Other acquired deformities of limbs	0.687	0.313
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.686	0.314
Z82.3 Family history of stroke	0.686	0.314
F38 Other mood [affective] disorders	0.686	0.314
F34 Persistent mood [affective] disorders	0.686	0.314
F30 Manic episode	0.686	0.314
F39 Unspecified mood [affective] disorder	0.686	0.314
Z88.7 Personal history of allergy to serum and vaccine	0.685	0.314
M75.5 Bursitis of shoulder	0.685	0.315
I78.1 Naevus, nonneoplastic	0.683	0.317
J99 Respiratory disorders in diseases classified elsewhere	0.683	0.317
J96 Respiratory failure, not elsewhere classified	0.683	0.317
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.682	0.318
I72 Other aneurysm	0.682	0.318
N03 Chronic nephritic syndrome	0.682	0.318
M75.8 Other shoulder lesions	0.682	0.318
M75.9 Shoulder lesion, unspecified	0.682	0.318
M75.3 Calcific tendinitis of shoulder	0.682	0.318
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.681	0.319
M10.9 Gout, unspecified	0.680	0.319
T43.2 Other and unspecified antidepressants	0.680	0.320
F41 Other anxiety disorders	0.680	0.320
E27 Other disorders of adrenal gland	0.679	0.321
I84.4 External haemorrhoids with other complications	0.679	0.321
O75 Other complications of labour and delivery, not elsewhere classified	0.679	0.321
M19.9 Arthrosis, unspecified	0.678	0.322
J98.0 Diseases of bronchus, not elsewhere classified	0.677	0.322
B97 Viral agents as the cause of diseases classified to other chapters	0.677	0.322
I84.1 Internal haemorrhoids with other complications	0.677	0.323
S69 Other and unspecified injuries of wrist and hand	0.677	0.323
S68 Traumatic amputation of wrist and hand	0.677	0.323
S65 Injury of blood vessels at wrist and hand level	0.677	0.323
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.677	0.323
C79.6 Secondary malignant neoplasm of ovary	0.677	0.323
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.677	0.323
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.677	0.323
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.677	0.323
I88 Nonspecific lymphadenitis	0.676	0.324
I85 Oesophageal varices	0.676	0.324
I82 Other venous embolism and thrombosis	0.676	0.324
I81 Portal vein thrombosis	0.676	0.324
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.676	0.324
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.676	0.324
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.676	0.324
T46 Poisoning by agents primarily affecting the cardiovascular system	0.676	0.324
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.676	0.324
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.676	0.324
T41 Poisoning by anaesthetics and therapeutic gases	0.676	0.324
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.676	0.324
T36 Poisoning by systemic antibiotics	0.676	0.324
N17.8 Other acute renal failure	0.675	0.325
N17.2 Acute renal failure with medullary necrosis	0.675	0.325
N17.1 Acute renal failure with acute cortical necrosis	0.675	0.325
N17.0 Acute renal failure with tubular necrosis	0.675	0.325
I31 Other diseases of pericardium	0.675	0.325
S61.0 Open wound of finger(s) without damage to nail	0.674	0.326
S29 Other and unspecified injuries of thorax	0.674	0.326
J69 Pneumonitis due to solids and liquids	0.673	0.327
M23.8 Other internal derangements of knee	0.673	0.327
E78.8 Other disorders of lipoprotein metabolism	0.672	0.327
E78.6 Lipoprotein deficiency	0.672	0.327
E78.4 Other hyperlipidaemia	0.672	0.327
E78.3 Hyperchylomicronaemia	0.672	0.327
E78.1 Pure hyperglyceridaemia	0.672	0.327
B15-B19 Viral hepatitis	0.672	0.328
I67 Other cerebrovascular diseases	0.672	0.328
Z93 Artificial opening status	0.671	0.329
E65-E68 Obesity and other hyperalimentation	0.671	0.329
E78.9 Disorder of lipoprotein metabolism, unspecified	0.671	0.329
M47.8 Other spondylosis	0.670	0.329
H92 Otalgia and effusion of ear	0.670	0.330
S00-S09 Injuries to the head	0.670	0.330
J90 Pleural effusion, not elsewhere classified	0.670	0.330
S22 Fracture of rib(s), sternum and thoracic spine	0.670	0.330
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.670	0.330
Z86.1 Personal history of infectious and parasitic diseases	0.669	0.331
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.668	0.332
J94 Other pleural conditions	0.668	0.332
E14 Unspecified diabetes mellitus	0.668	0.332
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.667	0.332
H65-H75 Diseases of middle ear and mastoid	0.667	0.333
J18.0 Bronchopneumonia, unspecified	0.667	0.333
F32.8 Other depressive episodes	0.667	0.333
F32.0 Mild depressive episode	0.667	0.333
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.666	0.333
Chapter XII Diseases of the skin and subcutaneous tissue	0.667	0.333
I51.9 Heart disease, unspecified	0.666	0.334
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.666	0.334
E55 Vitamin D deficiency	0.665	0.334
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.665	0.335
H94 Other disorders of ear in diseases classified elsewhere	0.665	0.335

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations