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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117116392
log Bayes Factor = 15.9603
Chromosome 13   position 36,649,606  (GRCh37) Explore rs117116392 on Ensembl!
Variant rs117116392 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Chapter II Neoplasms
0.992 0.008 0.000
Chapter XIV Diseases of the genitourinary system
0.985 0.015 0.000
K70-K77 Diseases of liver
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.982 0.018 0.000
E11 Non-insulin-dependent diabetes mellitus
0.980 0.020 0.000
N17-N19 Renal failure
0.979 0.021 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.978 0.022 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.974 0.026 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
I25.1 Atherosclerotic heart disease
0.970 0.030 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.967 0.033 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.959 0.041 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.958 0.042 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.955 0.045 0.000
N18 Chronic renal failure
0.954 0.046 0.000
K90-K93 Other diseases of the digestive system
0.953 0.047 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.952 0.048 0.000
N10-N16 Renal tubulo-interstitial diseases
0.949 0.051 0.000
O60-O75 Complications of labour and delivery
0.942 0.058 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.938 0.062 0.000
E70-E90 Metabolic disorders
0.937 0.063 0.000
K76 Other diseases of liver
0.933 0.067 0.000
E14 Unspecified diabetes mellitus
0.930 0.070 0.000
N19 Unspecified renal failure
0.929 0.071 0.000
E11.9 Without complications
0.926 0.074 0.000
I25.2 Old myocardial infarction
0.925 0.075 0.000
I05-I09 Chronic rheumatic heart diseases
0.922 0.078 0.000
E20-E35 Disorders of other endocrine glands
0.913 0.087 0.000
E10 Insulin-dependent diabetes mellitus
0.912 0.088 0.000
H30-H36 Disorders of choroid and retina
0.902 0.098 0.000
Chapter XXI Factors influencing health status and contact with health services
0.901 0.099 0.000
C15-C26 Malignant neoplasms of digestive organs
0.901 0.099 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.900 0.100 0.000
R50-R69 General symptoms and signs
0.896 0.104 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.895 0.105 0.000
K86 Other diseases of pancreas
0.892 0.108 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.892 0.108 0.000
I47 Paroxysmal tachycardia
0.892 0.108 0.000
E11.3 With ophthalmic complications
0.889 0.111 0.000
I50 Heart failure
0.888 0.112 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.886 0.114 0.000
N20-N23 Urolithiasis
0.881 0.119 0.000
K90 Intestinal malabsorption
0.880 0.120 0.000
N18.9 Chronic renal failure, unspecified
0.879 0.121 0.000
I83 Varicose veins of lower extremities
0.876 0.124 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.875 0.125 0.000
Chapter XX External causes of morbidity and mortality
0.874 0.126 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.869 0.131 0.000
O70 Perineal laceration during delivery
0.867 0.132 0.000
S50-S59 Injuries to the elbow and forearm
0.867 0.132 0.000
I08 Multiple valve diseases
0.864 0.136 0.000
E14.9 Without complications
0.862 0.138 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.860 0.140 0.000
E50-E64 Other nutritional deficiencies
0.860 0.140 0.000
H36 Retinal disorders in diseases classified elsewhere
0.857 0.143 0.000
C92 Myeloid leukaemia
0.855 0.145 0.000
I21 Acute myocardial infarction
0.849 0.151 0.000
K70 Alcoholic liver disease
0.845 0.155 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.843 0.157 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.841 0.159 0.000
K81 Cholecystitis
0.840 0.160 0.000
N13 Obstructive and reflux uropathy
0.836 0.164 0.000
I47.1 Supraventricular tachycardia
0.835 0.165 0.000
C78.7 Secondary malignant neoplasm of liver
0.835 0.165 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.833 0.167 0.000
N18.4 Chronic kidney disease, stage 4
0.830 0.170 0.000
R53 Malaise and fatigue
0.828 0.172 0.000
O63 Long labour
0.828 0.172 0.000
K90.0 Coeliac disease
0.827 0.173 0.000
R69 Unknown and unspecified causes of morbidity
0.827 0.173 0.000
N18.5 Chronic kidney disease, stage 5
0.826 0.174 0.000
S20-S29 Injuries to the thorax
0.825 0.174 0.000
H36.0 Diabetic retinopathy
0.824 0.176 0.000
K74 Fibrosis and cirrhosis of liver
0.824 0.176 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.822 0.178 0.000
E10.9 Without complications
0.822 0.178 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.820 0.180 0.000
H43-H45 Disorders of vitreous body and globe
0.816 0.184 0.000
I38 Endocarditis, valve unspecified
0.809 0.191 0.000
O70.1 Second degree perineal laceration during delivery
0.807 0.193 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.807 0.193 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.805 0.195 0.000
K40-K46 Hernia
0.803 0.197 0.000
E86 Volume depletion
0.802 0.198 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.800 0.200 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.798 0.202 0.000
I81 Portal vein thrombosis
0.798 0.202 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.798 0.202 0.000
K86.1 Other chronic pancreatitis
0.796 0.204 0.000
C92.0 Acute myeloid leukaemia
0.796 0.204 0.000
I49 Other cardiac arrhythmias
0.796 0.204 0.000
E13 Other specified diabetes mellitus
0.793 0.207 0.000
I35 Nonrheumatic aortic valve disorders
0.793 0.207 0.000
C20 Malignant neoplasm of rectum
0.791 0.208 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.790 0.210 0.000
N23 Unspecified renal colic
0.789 0.211 0.000
S52 Fracture of forearm
0.789 0.211 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.787 0.213 0.000
I42 Cardiomyopathy
0.786 0.214 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.785 0.215 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.785 0.215 0.000
O00-O08 Pregnancy with abortive outcome
0.784 0.216 0.000
Chapter I Certain infectious and parasitic diseases
0.784 0.216 0.000
K72 Hepatic failure, not elsewhere classified
0.783 0.217 0.000
Chapter VIII Diseases of the ear and mastoid process
0.782 0.218 0.000
Chapter VI Diseases of the nervous system
0.781 0.219 0.000
I50.1 Left ventricular failure
0.780 0.220 0.000
H25-H28 Disorders of lens
0.780 0.220 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.778 0.222 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.778 0.222 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.776 0.224 0.000
S00-S09 Injuries to the head
0.775 0.225 0.000
S80-S89 Injuries to the knee and lower leg
0.774 0.226 0.000
E11.4 With neurological complications
0.774 0.226 0.000
K85 Acute pancreatitis
0.770 0.230 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
I21.4 Acute subendocardial myocardial infarction
0.768 0.232 0.000
E78.0 Pure hypercholesterolaemia
0.765 0.235 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.763 0.237 0.000
I22 Subsequent myocardial infarction
0.763 0.237 0.000
O63.1 Prolonged second stage (of labour)
0.763 0.237 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.762 0.238 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.762 0.238 0.000
E53 Deficiency of other B group vitamins
0.760 0.240 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.759 0.241 0.000
K81.1 Chronic cholecystitis
0.759 0.241 0.000
D60-D64 Aplastic and other anaemias
0.757 0.243 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.757 0.243 0.000
Z53.8 Procedure not carried out for other reasons
0.756 0.244 0.000
K43 Ventral hernia
0.755 0.245 0.000
C51-C58 Malignant neoplasms of female genital organs
0.754 0.246 0.000
I77 Other disorders of arteries and arterioles
0.754 0.246 0.000
C16 Malignant neoplasm of stomach
0.751 0.249 0.000
I10-I15 Hypertensive diseases
0.750 0.250 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.749 0.251 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.747 0.253 0.000
K91.4 Colostomy and enterostomy malfunction
0.747 0.253 0.000
H55-H59 Other disorders of eye and adnexa
0.746 0.254 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
I08.0 Disorders of both mitral and aortic valves
0.744 0.256 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.743 0.256 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.742 0.258 0.000
E14.3 With ophthalmic complications
0.741 0.259 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.741 0.259 0.000
C80 Malignant neoplasm without specification of site
0.739 0.261 0.000
E28 Ovarian dysfunction
0.739 0.261 0.000
I31 Other diseases of pericardium
0.739 0.261 0.000
I86 Varicose veins of other sites
0.739 0.261 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.738 0.262 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.736 0.264 0.000
I84 Haemorrhoids
0.736 0.264 0.000
E10.3 With ophthalmic complications
0.735 0.265 0.000
T66-T78 Other and unspecified effects of external causes
0.733 0.267 0.000
K76.9 Liver disease, unspecified
0.732 0.268 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.730 0.270 0.000
H35 Other retinal disorders
0.730 0.270 0.000
N10 Acute tubulo-interstitial nephritis
0.730 0.270 0.000
O62 Abnormalities of forces of labour
0.728 0.272 0.000
O72 Postpartum haemorrhage
0.723 0.277 0.000
E83 Disorders of mineral metabolism
0.722 0.278 0.000
I24 Other acute ischaemic heart diseases
0.721 0.278 0.000
D45 Polycythaemia vera
0.721 0.279 0.000
H53-H54 Visual disturbances and blindness
0.721 0.279 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.721 0.279 0.000
H25 Senile cataract
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
E23 Hypofunction and other disorders of pituitary gland
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.715 0.285 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.714 0.286 0.000
K86.3 Pseudocyst of pancreas
0.714 0.286 0.000
I85 Oesophageal varices
0.713 0.286 0.000
E27 Other disorders of adrenal gland
0.713 0.287 0.000
S70-S79 Injuries to the hip and thigh
0.713 0.287 0.000
I08.8 Other multiple valve diseases
0.712 0.288 0.000
O66 Other obstructed labour
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
K74.6 Other and unspecified cirrhosis of liver
0.710 0.290 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.709 0.291 0.000
I70 Atherosclerosis
0.708 0.292 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.705 0.295 0.000
N18.0 End-stage renal disease
0.705 0.295 0.000
K77 Liver disorders in diseases classified elsewhere
0.704 0.295 0.000
K75 Other inflammatory liver diseases
0.704 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.704 0.295 0.000
K71 Toxic liver disease
0.704 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I33 Acute and subacute endocarditis
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
I30 Acute pericarditis
0.704 0.296 0.000
I74 Arterial embolism and thrombosis
0.704 0.296 0.000
Z30 Contraceptive management
0.704 0.296 0.000
E29 Testicular dysfunction
0.703 0.297 0.000
E11.8 With unspecified complications
0.703 0.297 0.000
E11.7 With multiple complications
0.703 0.297 0.000
E11.6 With other specified complications
0.703 0.297 0.000
E11.5 With peripheral circulatory complications
0.703 0.297 0.000
E11.2 With renal complications
0.703 0.297 0.000
E11.1 With ketoacidosis
0.703 0.297 0.000
E11.0 With coma
0.703 0.297 0.000
Z42 Follow-up care involving plastic surgery
0.702 0.298 0.000
I45 Other conduction disorders
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
T33-T35 Frostbite
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.701 0.299 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.701 0.299 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
T00-T07 Injuries involving multiple body regions
0.701 0.299 0.000
S10-S19 Injuries to the neck
0.701 0.299 0.000
N00-N08 Glomerular diseases
0.700 0.300 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.699 0.300 0.000
A30-A49 Other bacterial diseases
0.699 0.301 0.000
S40-S49 Injuries to the shoulder and upper arm
0.699 0.301 0.000
N20 Calculus of kidney and ureter
0.698 0.302 0.000
I50.0 Congestive heart failure
0.698 0.302 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.698 0.302 0.000
I78 Diseases of capillaries
0.697 0.303 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.696 0.304 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.696 0.304 0.000
H10-H13 Disorders of conjunctiva
0.696 0.304 0.000
M45-M49 Spondylopathies
0.696 0.304 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.695 0.305 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.695 0.305 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.693 0.306 0.000
R41.0 Disorientation, unspecified
0.693 0.307 0.000
O85-O92 Complications predominantly related to the puerperium
0.693 0.307 0.000
K86.2 Cyst of pancreas
0.693 0.307 0.000
W00-W19 Falls
0.692 0.308 0.000
S52.0 Fracture of upper end of ulna
0.692 0.308 0.000
N17 Acute renal failure
0.692 0.308 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.308 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.690 0.310 0.000
E53.8 Deficiency of other specified B group vitamins
0.688 0.312 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.688 0.312 0.000
R50 Fever of unknown origin
0.687 0.313 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.687 0.313 0.000
I88 Nonspecific lymphadenitis
0.687 0.313 0.000
I87 Other disorders of veins
0.687 0.313 0.000
I82 Other venous embolism and thrombosis
0.687 0.313 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.686 0.314 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.684 0.316 0.000
N18.8 Other chronic renal failure
0.684 0.316 0.000
N18.2 Chronic kidney disease, stage 2
0.684 0.316 0.000
N18.1 Chronic kidney disease, stage 1
0.684 0.316 0.000
Z60 Problems related to social environment
0.684 0.316 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.684 0.316 0.000
K86.8 Other specified diseases of pancreas
0.683 0.317 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.683 0.317 0.000
R27 Other lack of coordination
0.682 0.318 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.682 0.318 0.000
C25 Malignant neoplasm of pancreas
0.682 0.318 0.000
H43 Disorders of vitreous body
0.682 0.318 0.000
I21.9 Acute myocardial infarction, unspecified
0.681 0.319 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.681 0.319 0.000
N15 Other renal tubulo-interstitial diseases
0.681 0.319 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.681 0.319 0.000
N11 Chronic tubulo-interstitial nephritis
0.681 0.319 0.000
K70.9 Alcoholic liver disease, unspecified
0.680 0.320 0.000
K76.6 Portal hypertension
0.680 0.320 0.000
I50.9 Heart failure, unspecified
0.678 0.322 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.678 0.322 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.677 0.323 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.677 0.323 0.000
I07 Rheumatic tricuspid valve diseases
0.676 0.324 0.000
O74 Complications of anaesthesia during labour and delivery
0.676 0.324 0.000
O73 Retained placenta and membranes, without haemorrhage
0.676 0.324 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.676 0.324 0.000
O61 Failed induction of labour
0.676 0.324 0.000
O60 Preterm delivery
0.676 0.324 0.000
C78.2 Secondary malignant neoplasm of pleura
0.676 0.324 0.000
K70.1 Alcoholic hepatitis
0.675 0.325 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.675 0.325 0.000
K81.0 Acute cholecystitis
0.675 0.325 0.000
I80 Phlebitis and thrombophlebitis
0.674 0.326 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.673 0.326 0.000
R52 Pain, not elsewhere classified
0.673 0.327 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.673 0.327 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.672 0.327 0.000
C95 Leukaemia of unspecified cell type
0.672 0.327 0.000
C94 Other leukaemias of specified cell type
0.672 0.327 0.000
C93 Monocytic leukaemia
0.672 0.327 0.000
C88 Malignant immunoproliferative diseases
0.672 0.327 0.000
C86 Other specified types of T/NK-cell lymphoma
0.672 0.327 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.672 0.327 0.000
C81 Hodgkin's disease
0.672 0.327 0.000
N60-N64 Disorders of breast
0.672 0.327 0.000
K82 Other diseases of gallbladder
0.672 0.328 0.000
T81 Complications of procedures, not elsewhere classified
0.672 0.328 0.000
D46 Myelodysplastic syndromes
0.672 0.328 0.000
E88 Other metabolic disorders
0.672 0.328 0.000
E85 Amyloidosis
0.672 0.328 0.000
E84 Cystic fibrosis
0.672 0.328 0.000
E79 Disorders of purine and pyrimidine metabolism
0.672 0.328 0.000
E77 Disorders of glycoprotein metabolism
0.672 0.328 0.000
E76 Disorders of glycosaminoglycan metabolism
0.672 0.328 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.672 0.328 0.000
E74 Other disorders of carbohydrate metabolism
0.672 0.328 0.000
E73 Lactose intolerance
0.672 0.328 0.000
E72 Other disorders of amino-acid metabolism
0.672 0.328 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.672 0.328 0.000
E70 Disorders of aromatic amino-acid metabolism
0.672 0.328 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.672 0.328 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.671 0.329 0.000
C77.1 Intrathoracic lymph nodes
0.671 0.329 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.671 0.329 0.000
I12 Hypertensive renal disease
0.669 0.330 0.000
K76.7 Hepatorenal syndrome
0.669 0.331 0.000
K76.5 Hepatic veno-occlusive disease
0.669 0.331 0.000
K76.4 Peliosis hepatis
0.669 0.331 0.000
K76.3 Infarction of liver
0.669 0.331 0.000
K76.2 Central haemorrhagic necrosis of liver
0.669 0.331 0.000
K76.1 Chronic passive congestion of liver
0.669 0.331 0.000
Chapter V Mental and behavioural disorders
0.669 0.331 0.000
K55-K64 Other diseases of intestines
0.668 0.332 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.668 0.332 0.000
E14.8 With unspecified complications
0.667 0.333 0.000
E14.7 With multiple complications
0.667 0.333 0.000
E14.6 With other specified complications
0.667 0.333 0.000
E14.5 With peripheral circulatory complications
0.667 0.333 0.000
E14.4 With neurological complications
0.667 0.333 0.000
E14.2 Withrenal complications
0.667 0.333 0.000
E14.1 With ketoacidosis
0.667 0.333 0.000
E14.0 With coma
0.667 0.333 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.667 0.333 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.666 0.334 0.000
R60 Oedema, not elsewhere classified
0.664 0.336 0.000
I35.1 Aortic (valve) insufficiency
0.663 0.337 0.000
D48.7 Other specified sites
0.662 0.338 0.000
I09 Other rheumatic heart diseases
0.661 0.339 0.000
I06 Rheumatic aortic valve diseases
0.661 0.339 0.000
I05 Rheumatic mitral valve diseases
0.661 0.339 0.000
C34 Malignant neoplasm of bronchus and lung
0.659 0.341 0.000
S27 Injury of other and unspecified intrathoracic organs
0.658 0.341 0.000
I46 Cardiac arrest
0.658 0.341 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.658 0.342 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.657 0.343 0.000
N13.3 Other and unspecified hydronephrosis
0.657 0.343 0.000
R56 Convulsions, not elsewhere classified
0.657 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.657 0.343 0.000
I51 Complications and ill-defined descriptions of heart disease
0.657 0.343 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.655 0.345 0.000
E34 Other endocrine disorders
0.655 0.345 0.000
E32 Diseases of thymus
0.655 0.345 0.000
E31 Polyglandular dysfunction
0.655 0.345 0.000
E30 Disorders of puberty, not elsewhere classified
0.655 0.345 0.000
E26 Hyperaldosteronism
0.655 0.345 0.000
E25 Adrenogenital disorders
0.655 0.345 0.000
E24 Cushing's syndrome
0.655 0.345 0.000
E22 Hyperfunction of pituitary gland
0.655 0.345 0.000
E20 Hypoparathyroidism
0.655 0.345 0.000
R40 Somnolence, stupor and coma
0.655 0.345 0.000
E10.8 With unspecified complications
0.654 0.346 0.000
E10.7 With multiple complications
0.654 0.346 0.000
E10.6 With other specified complications
0.654 0.346 0.000
E10.5 With peripheral circulatory complications
0.654 0.346 0.000
E10.4 With neurological complications
0.654 0.346 0.000
E10.2 With renal complications
0.654 0.346 0.000
E10.1 With ketoacidosis
0.654 0.346 0.000
E10.0 With coma
0.654 0.346 0.000
N13.8 Other obstructive and reflux uropathy
0.653 0.347 0.000
Y40 Systemic antibiotics
0.653 0.347 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.652 0.348 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.652 0.348 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.652 0.348 0.000
C18 Malignant neoplasm of colon
0.651 0.348 0.000
C77.8 Lymph nodes of multiple regions
0.651 0.349 0.000
R26 Abnormalities of gait and mobility
0.651 0.349 0.000
N99-N99 Other disorders of the genitourinary system
0.650 0.350 0.000
Z43 Attention to artificial openings
0.650 0.350 0.000
C77.5 Intrapelvic lymph nodes
0.650 0.350 0.000
C91 Lymphoid leukaemia
0.649 0.351 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.649 0.351 0.000
O70.0 First degree perineal laceration during delivery
0.649 0.351 0.000
O04 Medical abortion
0.648 0.351 0.000
K83 Other diseases of biliary tract
0.648 0.352 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.647 0.353 0.000
H31 Other disorders of choroid
0.647 0.353 0.000
H30 Chorioretinal inflammation
0.647 0.353 0.000
Z54 Convalescence
0.647 0.353 0.000
C79 Secondary malignant neoplasm of other sites
0.646 0.354 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.646 0.354 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.646 0.354 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.646 0.354 0.000
C21 Malignant neoplasm of anus and anal canal
0.646 0.354 0.000
C17 Malignant neoplasm of small intestine
0.646 0.354 0.000
C23 Malignant neoplasm of gallbladder
0.646 0.354 0.000
E13.9 Without complications
0.646 0.354 0.000
Z30.2 Sterilisation
0.646 0.354 0.000
R68 Other general symptoms and signs
0.645 0.355 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.644 0.356 0.000
K70.3 Alcoholic cirrhosis of liver
0.644 0.356 0.000
G20-G26 Extrapyramidal and movement disorders
0.644 0.356 0.000
S00 Superficial injury of head
0.644 0.356 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.643 0.357 0.000
R62 Lack of expected normal physiological development
0.643 0.357 0.000
R57 Shock, not elsewhere classified
0.643 0.357 0.000
R64 Cachexia
0.643 0.357 0.000
R58 Haemorrhage, not elsewhere classified
0.643 0.357 0.000
N18.3 Chronic kidney disease, stage 3
0.642 0.358 0.000
W20-W49 Exposure to inanimate mechanical forces
0.642 0.358 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.641 0.359 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.641 0.359 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.641 0.359 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.641 0.359 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.641 0.359 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.641 0.359 0.000
K72.9 Hepatic failure, unspecified
0.640 0.360 0.000
K86.9 Disease of pancreas, unspecified
0.640 0.360 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.640 0.360 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.640 0.360 0.000
I72 Other aneurysm
0.640 0.360 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.640 0.360 0.000
I47.0 Reentry ventricular arrhythmia
0.640 0.360 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.640 0.360 0.000
K65-K67 Diseases of peritoneum
0.637 0.363 0.000
I49.4 Other and unspecified premature depolarisation
0.637 0.363 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.635 0.365 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.635 0.365 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.635 0.365 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.635 0.365 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.635 0.365 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.635 0.365 0.000
R45 Symptoms and signs involving emotional state
0.635 0.365 0.000
Z49 Care involving dialysis
0.635 0.365 0.000
S52.6 Fracture of lower end of both ulna and radius
0.635 0.365 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.635 0.365 0.000
I42.0 Dilated cardiomyopathy
0.634 0.366 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.633 0.367 0.000
R59 Enlarged lymph nodes
0.633 0.367 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.632 0.368 0.000
H25.9 Senile cataract, unspecified
0.632 0.368 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.632 0.368 0.000
H49 Paralytic strabismus
0.632 0.368 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.632 0.368 0.000
C54 Malignant neoplasm of corpus uteri
0.631 0.369 0.000
O80-O84 Delivery
0.631 0.369 0.000
K90.9 Intestinal malabsorption, unspecified
0.631 0.369 0.000
K90.8 Other intestinal malabsorption
0.631 0.369 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.631 0.369 0.000
K90.3 Pancreatic steatorrhoea
0.631 0.369 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.631 0.369 0.000
K90.1 Tropical sprue
0.631 0.369 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.631 0.369 0.000
B99-B99 Other infectious diseases
0.631 0.369 0.000
H60-H62 Diseases of external ear
0.630 0.370 0.000
I44 Atrioventricular and left bundle-branch block
0.630 0.370 0.000
K62 Other diseases of anus and rectum
0.630 0.370 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.628 0.372 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.628 0.372 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.626 0.373 0.000
Y35-Y36 Legal intervention and operations of war
0.626 0.373 0.000
Y10-Y34 Event of undetermined intent
0.626 0.373 0.000
Y00-Y09 Assault
0.626 0.373 0.000
X85-X99 Assault
0.626 0.373 0.000
X60-X84 Intentional self-harm
0.626 0.373 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.626 0.373 0.000
X50-X57 Overexertion, travel and privation
0.626 0.373 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.626 0.373 0.000
X30-X39 Exposure to forces of nature
0.626 0.373 0.000
X20-X29 Contact with venomous animals and plants
0.626 0.373 0.000
X10-X19 Contact with heat and hot substances
0.626 0.373 0.000
X00-X09 Exposure to smoke, fire and flames
0.626 0.373 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.626 0.373 0.000
W75-W84 Other accidental threats to breathing
0.626 0.373 0.000
W65-W74 Accidental drowning and submersion
0.626 0.373 0.000
W50-W64 Exposure to animate mechanical forces
0.626 0.373 0.000
V98-V99 Other and unspecified transport accidents
0.626 0.373 0.000
V95-V97 Air and space transport accidents
0.626 0.373 0.000
V90-V94 Water transport accidents
0.626 0.373 0.000
V80-V89 Other land transport accidents
0.626 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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