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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117197053
log Bayes Factor = 22.648
Chromosome 6   position 154,076,889  (GRCh37) Explore rs117197053 on Ensembl!
Variant rs117197053 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
E10.9 Without complications
0.996 0.004 0.000
N17-N19 Renal failure
0.995 0.005 0.000
H25-H28 Disorders of lens
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.991 0.009 0.000
H26 Other cataract
0.989 0.011 0.000
S80-S89 Injuries to the knee and lower leg
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.986 0.014 0.000
H35 Other retinal disorders
0.984 0.016 0.000
N20-N23 Urolithiasis
0.984 0.016 0.000
N10-N16 Renal tubulo-interstitial diseases
0.983 0.017 0.000
M45-M49 Spondylopathies
0.979 0.021 0.000
N17 Acute renal failure
0.977 0.023 0.000
H33 Retinal detachments and breaks
0.977 0.023 0.000
H26.9 Cataract, unspecified
0.968 0.032 0.000
N18 Chronic renal failure
0.967 0.033 0.000
E11 Non-insulin-dependent diabetes mellitus
0.967 0.033 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.966 0.034 0.000
N17.9 Acute renal failure, unspecified
0.964 0.036 0.000
S60-S69 Injuries to the wrist and hand
0.962 0.038 0.000
N13 Obstructive and reflux uropathy
0.960 0.040 0.000
S82 Fracture of lower leg, including ankle
0.959 0.041 0.000
Chapter II Neoplasms
0.957 0.043 0.000
M47 Spondylosis
0.952 0.048 0.000
H36 Retinal disorders in diseases classified elsewhere
0.951 0.049 0.000
E10.3 With ophthalmic complications
0.948 0.052 0.000
H34 Retinal vascular occlusions
0.943 0.057 0.000
H35.3 Degeneration of macula and posterior pole
0.943 0.057 0.000
Chapter IX Diseases of the circulatory system
0.940 0.060 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.938 0.062 0.000
G90-G99 Other disorders of the nervous system
0.935 0.065 0.000
N18.9 Chronic renal failure, unspecified
0.932 0.068 0.000
N23 Unspecified renal colic
0.931 0.069 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.929 0.071 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.926 0.074 0.000
Chapter X Diseases of the respiratory system
0.923 0.077 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.923 0.077 0.000
Chapter I Certain infectious and parasitic diseases
0.923 0.077 0.000
N20 Calculus of kidney and ureter
0.922 0.078 0.000
M50-M54 Other dorsopathies
0.922 0.078 0.000
M48 Other spondylopathies
0.920 0.080 0.000
H33.2 Serous retinal detachment
0.917 0.083 0.000
E87.6 Hypokalaemia
0.916 0.084 0.000
H36.0 Diabetic retinopathy
0.916 0.084 0.000
Chapter XX External causes of morbidity and mortality
0.916 0.084 0.000
S82.8 Fractures of other parts of lower leg
0.913 0.087 0.000
H26.4 After-cataract
0.912 0.088 0.000
E11.9 Without complications
0.907 0.093 0.000
Chapter VIII Diseases of the ear and mastoid process
0.907 0.093 0.000
N60-N64 Disorders of breast
0.903 0.097 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.903 0.097 0.000
N13.3 Other and unspecified hydronephrosis
0.901 0.099 0.000
G40-G47 Episodic and paroxysmal disorders
0.895 0.105 0.000
I10-I15 Hypertensive diseases
0.895 0.105 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.893 0.107 0.000
S00-S09 Injuries to the head
0.892 0.108 0.000
M47.9 Spondylosis, unspecified
0.890 0.110 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.889 0.111 0.000
H35.8 Other specified retinal disorders
0.887 0.113 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.886 0.113 0.000
Chapter V Mental and behavioural disorders
0.881 0.119 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.880 0.120 0.000
G20-G26 Extrapyramidal and movement disorders
0.880 0.120 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.878 0.122 0.000
M48.0 Spinal stenosis
0.878 0.122 0.000
E83 Disorders of mineral metabolism
0.877 0.123 0.000
H34.8 Other retinal vascular occlusions
0.876 0.124 0.000
H43-H45 Disorders of vitreous body and globe
0.875 0.125 0.000
E11.3 With ophthalmic complications
0.874 0.126 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
N30-N39 Other diseases of urinary system
0.871 0.129 0.000
I73 Other peripheral vascular diseases
0.868 0.132 0.000
A30-A49 Other bacterial diseases
0.867 0.133 0.000
H55-H59 Other disorders of eye and adnexa
0.866 0.134 0.000
M47.8 Other spondylosis
0.864 0.136 0.000
W00-W19 Falls
0.864 0.136 0.000
E78.5 Hyperlipidaemia, unspecified
0.862 0.138 0.000
I10 Essential (primary) hypertension
0.861 0.139 0.000
N20.1 Calculus of ureter
0.860 0.140 0.000
E10.1 With ketoacidosis
0.857 0.143 0.000
R47-R49 Symptoms and signs involving speech and voice
0.856 0.144 0.000
C44 Other malignant neoplasms of skin
0.853 0.147 0.000
H33.3 Retinal breaks without detachment
0.852 0.148 0.000
I77 Other disorders of arteries and arterioles
0.847 0.153 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.844 0.156 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.835 0.165 0.000
E87.7 Fluid overload
0.833 0.167 0.000
S64 Injury of nerves at wrist and hand level
0.832 0.168 0.000
E10.4 With neurological complications
0.829 0.171 0.000
I73.9 Peripheral vascular disease, unspecified
0.828 0.172 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.827 0.173 0.000
T79-T79 Certain early complications of trauma
0.825 0.175 0.000
H90-H95 Other disorders of ear
0.824 0.176 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.823 0.177 0.000
M50 Cervical disk disorders
0.820 0.180 0.000
G47 Sleep disorders
0.819 0.181 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.819 0.181 0.000
H26.2 Complicated cataract
0.816 0.184 0.000
E78.2 Mixed hyperlipidaemia
0.814 0.186 0.000
G93 Other disorders of brain
0.813 0.187 0.000
S82.2 Fracture of shaft of tibia
0.812 0.188 0.000
E20-E35 Disorders of other endocrine glands
0.811 0.189 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.807 0.193 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.807 0.193 0.000
J20-J22 Other acute lower respiratory infections
0.806 0.194 0.000
H33.0 Retinal detachment with retinal break
0.805 0.195 0.000
D10-D36 Benign neoplasms
0.805 0.195 0.000
S40-S49 Injuries to the shoulder and upper arm
0.803 0.197 0.000
J00-J06 Acute upper respiratory infections
0.801 0.199 0.000
R47 Speech disturbances, not elsewhere classified
0.800 0.200 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.799 0.201 0.000
C44.1 Skin of eyelid, including canthus
0.799 0.201 0.000
J95-J99 Other diseases of the respiratory system
0.797 0.203 0.000
W19 Unspecified fall
0.797 0.203 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.796 0.204 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.796 0.204 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.794 0.206 0.000
H20 Iridocyclitis
0.793 0.207 0.000
C44.0 Skin of lip
0.792 0.208 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.792 0.208 0.000
G95 Other diseases of spinal cord
0.792 0.208 0.000
N64 Other disorders of breast
0.790 0.210 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.789 0.211 0.000
N62 Hypertrophy of breast
0.787 0.213 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.786 0.214 0.000
H91 Other hearing loss
0.786 0.214 0.000
M05-M14 Inflammatory polyarthropathies
0.785 0.215 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.785 0.215 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.785 0.215 0.000
H34.2 Other retinal artery occlusions
0.785 0.215 0.000
E10.5 With peripheral circulatory complications
0.784 0.216 0.000
C44.7 Skin of lower limb, including hip
0.783 0.217 0.000
D00-D09 In situ neoplasms
0.783 0.217 0.000
H10-H13 Disorders of conjunctiva
0.782 0.218 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
E83.5 Disorders of calcium metabolism
0.781 0.219 0.000
N25-N29 Other disorders of kidney and ureter
0.781 0.219 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.780 0.220 0.000
S09 Other and unspecified injuries of head
0.780 0.220 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.779 0.221 0.000
N18.5 Chronic kidney disease, stage 5
0.779 0.221 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.776 0.224 0.000
C50-C50 Malignant neoplasm of breast
0.776 0.224 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.776 0.224 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.775 0.225 0.000
M48.02 Spinal stenosis (Cervical region)
0.774 0.226 0.000
G30-G32 Other degenerative diseases of the nervous system
0.773 0.227 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.773 0.227 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.771 0.229 0.000
N11 Chronic tubulo-interstitial nephritis
0.771 0.229 0.000
E87.3 Alkalosis
0.770 0.230 0.000
S50-S59 Injuries to the elbow and forearm
0.769 0.231 0.000
M51 Other intervertebral disk disorders
0.768 0.232 0.000
E78.8 Other disorders of lipoprotein metabolism
0.766 0.234 0.000
M47.86 Other spondylosis (Lumbar region)
0.766 0.234 0.000
H40-H42 Glaucoma
0.765 0.235 0.000
T66-T78 Other and unspecified effects of external causes
0.764 0.236 0.000
N13.4 Hydroureter
0.764 0.236 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.763 0.237 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.761 0.239 0.000
E87.2 Acidosis
0.759 0.241 0.000
N18.0 End-stage renal disease
0.759 0.241 0.000
H26.8 Other specified cataract
0.759 0.241 0.000
H91.9 Hearing loss, unspecified
0.758 0.242 0.000
S80 Superficial injury of lower leg
0.757 0.243 0.000
G47.3 Sleep apnoea
0.757 0.243 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.756 0.243 0.000
I72 Other aneurysm
0.756 0.244 0.000
A41 Other septicaemia
0.755 0.245 0.000
G20 Parkinson's disease
0.755 0.245 0.000
Chapter XXII Codes for special purposes
0.755 0.245 0.000
S20-S29 Injuries to the thorax
0.755 0.245 0.000
D12.5 Sigmoid colon
0.754 0.246 0.000
E50-E64 Other nutritional deficiencies
0.754 0.246 0.000
M48.09 Spinal stenosis (Site unspecified)
0.753 0.247 0.000
R47.8 Other and unspecified speech disturbances
0.752 0.248 0.000
M50.0 Cervical disk disorder with myelopathy
0.752 0.248 0.000
E83.4 Disorders of magnesium metabolism
0.751 0.249 0.000
H35.0 Background retinopathy and retinal vascular changes
0.751 0.249 0.000
H43 Disorders of vitreous body
0.747 0.253 0.000
N76 Other inflammation of vagina and vulva
0.746 0.254 0.000
J09-J18 Influenza and pneumonia
0.746 0.254 0.000
M80-M85 Disorders of bone density and structure
0.745 0.254 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.745 0.255 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.743 0.257 0.000
H57 Other disorders of eye and adnexa
0.743 0.257 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.742 0.258 0.000
C64-C68 Malignant neoplasms of urinary tract
0.742 0.258 0.000
S81 Open wound of lower leg
0.742 0.258 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.741 0.259 0.000
S69 Other and unspecified injuries of wrist and hand
0.741 0.259 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.740 0.260 0.000
C90.0 Multiple myeloma
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.738 0.262 0.000
N39 Other disorders of urinary system
0.738 0.262 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.738 0.262 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.737 0.263 0.000
S62 Fracture at wrist and hand level
0.736 0.264 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.736 0.264 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.736 0.264 0.000
C44.2 Skin of ear and external auricular canal
0.736 0.264 0.000
N73 Other female pelvic inflammatory diseases
0.735 0.265 0.000
S61 Open wound of wrist and hand
0.735 0.265 0.000
E11.4 With neurological complications
0.734 0.266 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.734 0.266 0.000
E87.0 Hyperosmolality and hypernatraemia
0.732 0.267 0.000
N20.0 Calculus of kidney
0.733 0.267 0.000
A49 Bacterial infection of unspecified site
0.732 0.268 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.731 0.269 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.731 0.269 0.000
E87.5 Hyperkalaemia
0.730 0.270 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.729 0.271 0.000
S83.2 Tear of meniscus, current
0.729 0.271 0.000
M47.89 Other spondylosis (Site unspecified)
0.729 0.271 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.728 0.272 0.000
S82.1 Fracture of upper end of tibia
0.727 0.273 0.000
S82.3 Fracture of lower end of tibia
0.727 0.273 0.000
H35.4 Peripheral retinal degeneration
0.726 0.274 0.000
R29.6 Tendency to fall, not elsewhere classified
0.726 0.274 0.000
J02 Acute pharyngitis
0.725 0.275 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.724 0.276 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.723 0.277 0.000
J22 Unspecified acute lower respiratory infection
0.722 0.278 0.000
B95-B98 Bacterial, viral and other infectious agents
0.722 0.278 0.000
J98 Other respiratory disorders
0.722 0.278 0.000
M54 Dorsalgia
0.721 0.279 0.000
B99-B99 Other infectious diseases
0.721 0.279 0.000
M45 Ankylosing spondylitis
0.721 0.279 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.720 0.280 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.282 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H31 Other disorders of choroid
0.717 0.283 0.000
H30 Chorioretinal inflammation
0.717 0.283 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.2 With renal complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.716 0.284 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.716 0.284 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.285 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.714 0.285 0.000
H20.9 Iridocyclitis, unspecified
0.714 0.286 0.000
G44 Other headache syndromes
0.714 0.286 0.000
R40 Somnolence, stupor and coma
0.713 0.287 0.000
G25 Other extrapyramidal and movement disorders
0.712 0.287 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.712 0.287 0.000
H27 Other disorders of lens
0.712 0.287 0.000
S82.4 Fracture of fibula alone
0.712 0.288 0.000
I71 Aortic aneurysm and dissection
0.712 0.288 0.000
S64.4 Injury of digital nerve of other finger
0.711 0.289 0.000
E85 Amyloidosis
0.711 0.289 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
E73 Lactose intolerance
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
R26 Abnormalities of gait and mobility
0.710 0.290 0.000
N21 Calculus of lower urinary tract
0.710 0.290 0.000
H26.3 Drug-induced cataract
0.709 0.291 0.000
H26.1 Traumatic cataract
0.709 0.291 0.000
H26.0 Infantile, juvenile and presenile cataract
0.709 0.291 0.000
D12.3 Transverse colon
0.709 0.291 0.000
S89 Other and unspecified injuries of lower leg
0.709 0.291 0.000
S88 Traumatic amputation of lower leg
0.709 0.291 0.000
S87 Crushing injury of lower leg
0.709 0.291 0.000
S86 Injury of muscle and tendon at lower leg level
0.709 0.291 0.000
S85 Injury of blood vessels at lower leg level
0.709 0.291 0.000
S84 Injury of nerves at lower leg level
0.709 0.291 0.000
M46 Other inflammatory spondylopathies
0.708 0.292 0.000
A46 Erysipelas
0.708 0.292 0.000
H65-H75 Diseases of middle ear and mastoid
0.708 0.292 0.000
M91-M94 Chondropathies
0.707 0.293 0.000
M60-M63 Disorders of muscles
0.707 0.293 0.000
M00-M03 Infectious arthropathies
0.707 0.293 0.000
S01 Open wound of head
0.707 0.293 0.000
S82.20 Fracture of shaft of tibia (closed)
0.707 0.293 0.000
H35.9 Retinal disorder, unspecified
0.706 0.294 0.000
H35.7 Separation of retinal layers
0.706 0.294 0.000
H35.6 Retinal haemorrhage
0.706 0.294 0.000
H35.5 Hereditary retinal dystrophy
0.706 0.294 0.000
H35.2 Other proliferative retinopathy
0.706 0.294 0.000
H35.1 Retinopathy of prematurity
0.706 0.294 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.706 0.294 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.705 0.295 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.705 0.295 0.000
N15 Other renal tubulo-interstitial diseases
0.705 0.295 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.705 0.295 0.000
N10 Acute tubulo-interstitial nephritis
0.705 0.295 0.000
D24 Benign neoplasm of breast
0.705 0.295 0.000
G93.3 Postviral fatigue syndrome
0.704 0.296 0.000
H44 Disorders of globe
0.703 0.297 0.000
N18.4 Chronic kidney disease, stage 4
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.702 0.298 0.000
S70-S79 Injuries to the hip and thigh
0.702 0.298 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.702 0.298 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.700 0.300 0.000
N17.8 Other acute renal failure
0.700 0.300 0.000
N17.2 Acute renal failure with medullary necrosis
0.700 0.300 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.700 0.300 0.000
N17.0 Acute renal failure with tubular necrosis
0.700 0.300 0.000
H33.5 Other retinal detachments
0.700 0.300 0.000
H33.4 Traction detachment of retina
0.700 0.300 0.000
H33.1 Retinoschisis and retinal cysts
0.700 0.300 0.000
N99-N99 Other disorders of the genitourinary system
0.700 0.300 0.000
S06 Intracranial injury
0.700 0.300 0.000
H25 Senile cataract
0.700 0.300 0.000
S09.9 Unspecified injury of head
0.700 0.300 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.699 0.301 0.000
M48.06 Spinal stenosis (Lumbar region)
0.698 0.302 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.697 0.303 0.000
H21 Other disorders of iris and ciliary body
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
H80-H83 Diseases of inner ear
0.695 0.305 0.000
V80-V89 Other land transport accidents
0.694 0.306 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.694 0.306 0.000
N18.8 Other chronic renal failure
0.693 0.307 0.000
N18.1 Chronic kidney disease, stage 1
0.693 0.307 0.000
E11.8 With unspecified complications
0.693 0.307 0.000
E11.7 With multiple complications
0.693 0.307 0.000
E11.6 With other specified complications
0.693 0.307 0.000
E11.1 With ketoacidosis
0.693 0.307 0.000
E11.0 With coma
0.693 0.307 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.693 0.307 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.693 0.307 0.000
E87.4 Mixed disorder of acid-base balance
0.693 0.307 0.000
M47.2 Other spondylosis with radiculopathy
0.692 0.308 0.000
W19.2 School, other institution and public administrative area
0.691 0.309 0.000
J30-J39 Other diseases of upper respiratory tract
0.691 0.309 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.691 0.309 0.000
N00-N08 Glomerular diseases
0.691 0.309 0.000
S67 Crushing injury of wrist and hand
0.690 0.310 0.000
S65 Injury of blood vessels at wrist and hand level
0.690 0.310 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.690 0.310 0.000
I70 Atherosclerosis
0.689 0.310 0.000
M65-M68 Disorders of synovium and tendon
0.689 0.310 0.000
B25-B34 Other viral diseases
0.689 0.311 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.688 0.312 0.000
N13.6 Pyonephrosis
0.688 0.312 0.000
S82.9 Fracture of lower leg, part unspecified
0.688 0.312 0.000
S82.7 Multiple fractures of lower leg
0.688 0.312 0.000
S82.5 Fracture of medial malleolus
0.688 0.312 0.000
S82.0 Fracture of patella
0.688 0.312 0.000
S60 Superficial injury of wrist and hand
0.687 0.313 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.686 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.686 0.314 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.686 0.314 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.685 0.315 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.685 0.315 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
M47.1 Other spondylosis with myelopathy
0.682 0.317 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.682 0.317 0.000
N32 Other disorders of bladder
0.682 0.318 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.682 0.318 0.000
H18 Other disorders of cornea
0.682 0.318 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.681 0.319 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.681 0.319 0.000
W06 Fall involving bed
0.680 0.320 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.679 0.321 0.000
N13.8 Other obstructive and reflux uropathy
0.679 0.321 0.000
N18.3 Chronic kidney disease, stage 3
0.678 0.322 0.000
N75 Diseases of Bartholin's gland
0.677 0.322 0.000
D12.4 Descending colon
0.677 0.323 0.000
H55 Nystagmus and other irregular eye movements
0.677 0.323 0.000
H34.9 Retinal vascular occlusion, unspecified
0.676 0.323 0.000
H34.1 Central retinal artery occlusion
0.676 0.323 0.000
H34.0 Transient retinal artery occlusion
0.676 0.323 0.000
F10.0 Acute intoxication
0.676 0.324 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.675 0.325 0.000
I77.1 Stricture of artery
0.674 0.326 0.000
I00-I02 Acute rheumatic fever
0.674 0.326 0.000
G58 Other mononeuropathies
0.673 0.327 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.673 0.327 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.673 0.327 0.000
N18.2 Chronic kidney disease, stage 2
0.673 0.327 0.000
G35 Multiple sclerosis
0.673 0.327 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.671 0.328 0.000
H16 Keratitis
0.671 0.329 0.000
T59 Toxic effect of other gases, fumes and vapours
0.671 0.329 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.670 0.329 0.000
G96 Other disorders of central nervous system
0.670 0.329 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.670 0.329 0.000
G90 Disorders of autonomic nervous system
0.670 0.329 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.670 0.329 0.000
G92 Toxic encephalopathy
0.670 0.329 0.000
J02.9 Acute pharyngitis, unspecified
0.671 0.329 0.000
A41.9 Septicaemia, unspecified
0.670 0.330 0.000
N63 Unspecified lump in breast
0.670 0.330 0.000
N64.1 Fat necrosis of breast
0.669 0.331 0.000
M06 Other rheumatoid arthritis
0.668 0.332 0.000
N20.2 Calculus of kidney with calculus of ureter
0.667 0.333 0.000
X60-X84 Intentional self-harm
0.666 0.334 0.000
E78.6 Lipoprotein deficiency
0.666 0.334 0.000
E78.4 Other hyperlipidaemia
0.666 0.334 0.000
E78.3 Hyperchylomicronaemia
0.666 0.334 0.000
E78.1 Pure hyperglyceridaemia
0.666 0.334 0.000
E88 Other metabolic disorders
0.665 0.335 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.335 0.000
W08 Fall involving other furniture
0.664 0.336 0.000
R45 Symptoms and signs involving emotional state
0.664 0.336 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.664 0.336 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.663 0.337 0.000
E11.2 With renal complications
0.663 0.337 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.662 0.338 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.662 0.338 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.662 0.338 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.662 0.338 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.662 0.338 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
T36 Poisoning by systemic antibiotics
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.661 0.338 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.661 0.338 0.000
B65-B83 Helminthiases
0.661 0.338 0.000
B50-B64 Protozoal diseases
0.661 0.338 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.661 0.338 0.000
B15-B19 Viral hepatitis
0.661 0.338 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.661 0.338 0.000
A75-A79 Rickettsioses
0.661 0.338 0.000
A70-A74 Other diseases caused by chlamydiae
0.661 0.338 0.000
A65-A69 Other spirochaetal diseases
0.661 0.338 0.000
A20-A28 Certain zoonotic bacterial diseases
0.661 0.338 0.000
A15-A19 Tuberculosis
0.661 0.338 0.000
N20.9 Urinary calculus, unspecified
0.661 0.339 0.000
M53 Other dorsopathies, not elsewhere classified
0.661 0.339 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.661 0.339 0.000
D18 Haemangioma and lymphangioma, any site
0.660 0.340 0.000
N39.3 Stress incontinence
0.660 0.340 0.000
I12 Hypertensive renal disease
0.660 0.340 0.000
M48.9 Spondylopathy, unspecified
0.660 0.340 0.000
M48.8 Other specified spondylopathies
0.660 0.340 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.660 0.340 0.000
M48.4 Fatigue fracture of vertebra
0.660 0.340 0.000
M48.3 Traumatic spondylopathy
0.660 0.340 0.000
M48.2 Kissing spine
0.660 0.340 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.660 0.340 0.000
J60-J70 Lung diseases due to external agents
0.659 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.656 0.343 0.000
Y35-Y36 Legal intervention and operations of war
0.656 0.343 0.000
Y10-Y34 Event of undetermined intent
0.656 0.343 0.000
Y00-Y09 Assault
0.656 0.343 0.000
X85-X99 Assault
0.656 0.343 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.656 0.343 0.000
X50-X57 Overexertion, travel and privation
0.656 0.343 0.000
X30-X39 Exposure to forces of nature
0.656 0.343 0.000
X20-X29 Contact with venomous animals and plants
0.656 0.343 0.000
X10-X19 Contact with heat and hot substances
0.656 0.343 0.000
X00-X09 Exposure to smoke, fire and flames
0.656 0.343 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.656 0.343 0.000
W75-W84 Other accidental threats to breathing
0.656 0.343 0.000
W65-W74 Accidental drowning and submersion
0.656 0.343 0.000
W50-W64 Exposure to animate mechanical forces
0.656 0.343 0.000
V98-V99 Other and unspecified transport accidents
0.656 0.343 0.000
V95-V97 Air and space transport accidents
0.656 0.343 0.000
V90-V94 Water transport accidents
0.656 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.656 0.343 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.656 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.656 0.343 0.000
V40-V49 Car occupant injured in transport accident
0.656 0.343 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.656 0.343 0.000
V01-V09 Pedestrian injured in transport accident
0.656 0.343 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.656 0.344 0.000
G95.9 Disease of spinal cord, unspecified
0.656 0.344 0.000
D10 Benign neoplasm of mouth and pharynx
0.655 0.345 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.655 0.345 0.000
W20-W49 Exposure to inanimate mechanical forces
0.655 0.345 0.000
S82.86 Maisonneuve's fracture
0.654 0.345 0.000
S82.81 Fractures of other parts of lower leg (open)
0.654 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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