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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117231330
log Bayes Factor = 14.3463
Chromosome 15   position 81,214,019  (GRCh37) Explore rs117231330 on Ensembl!
Variant rs117231330 is part of Cluster X0095

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
M54 Dorsalgia
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.999 0.001 0.000
M54.5 Low back pain
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.992 0.008 0.000
Chapter XI Diseases of the digestive system
0.992 0.008 0.000
F10.2 Dependence syndrome
0.991 0.009 0.000
K70-K77 Diseases of liver
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.984 0.016 0.000
S00-S09 Injuries to the head
0.981 0.019 0.000
Chapter VII Diseases of the eye and adnexa
0.974 0.026 0.000
H40-H42 Glaucoma
0.973 0.027 0.000
H40 Glaucoma
0.972 0.028 0.000
I51 Complications and ill-defined descriptions of heart disease
0.970 0.030 0.000
K70 Alcoholic liver disease
0.969 0.031 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.968 0.032 0.000
G40-G47 Episodic and paroxysmal disorders
0.965 0.035 0.000
M54.56 Low back pain (Lumbar region)
0.962 0.038 0.000
M65-M68 Disorders of synovium and tendon
0.958 0.042 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.954 0.046 0.000
H40.2 Primary angle-closure glaucoma
0.949 0.051 0.000
Chapter XXII Codes for special purposes
0.949 0.051 0.000
G47 Sleep disorders
0.945 0.055 0.000
S06 Intracranial injury
0.943 0.057 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.940 0.060 0.000
T90 Sequelae of injuries of head
0.939 0.061 0.000
Chapter XIV Diseases of the genitourinary system
0.938 0.062 0.000
I60-I69 Cerebrovascular diseases
0.937 0.063 0.000
H40.9 Glaucoma, unspecified
0.936 0.064 0.000
M54.59 Low back pain (Site unspecified)
0.933 0.067 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.931 0.069 0.000
F10.0 Acute intoxication
0.929 0.071 0.000
S02 Fracture of skull and facial bones
0.927 0.073 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.923 0.077 0.000
K70.9 Alcoholic liver disease, unspecified
0.918 0.082 0.000
K40-K46 Hernia
0.917 0.083 0.000
Chapter XX External causes of morbidity and mortality
0.916 0.084 0.000
G47.9 Sleep disorder, unspecified
0.913 0.087 0.000
K90-K93 Other diseases of the digestive system
0.911 0.089 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.909 0.091 0.000
Chapter II Neoplasms
0.907 0.093 0.000
I51.7 Cardiomegaly
0.901 0.099 0.000
F80-F89 Disorders of psychological development
0.898 0.102 0.000
U80 Agent resistant to penicillin and related antibiotics
0.897 0.103 0.000
M40-M43 Deforming dorsopathies
0.896 0.104 0.000
M65 Synovitis and tenosynovitis
0.895 0.105 0.000
I50 Heart failure
0.894 0.106 0.000
G90-G99 Other disorders of the nervous system
0.894 0.106 0.000
I30 Acute pericarditis
0.893 0.107 0.000
I47 Paroxysmal tachycardia
0.890 0.110 0.000
M91-M94 Chondropathies
0.886 0.114 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.882 0.118 0.000
N10-N16 Renal tubulo-interstitial diseases
0.879 0.121 0.000
M54.2 Cervicalgia
0.876 0.124 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.876 0.124 0.000
H40.1 Primary open-angle glaucoma
0.872 0.128 0.000
I44 Atrioventricular and left bundle-branch block
0.871 0.129 0.000
I47.2 Ventricular tachycardia
0.869 0.131 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.865 0.135 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.865 0.135 0.000
S80-S89 Injuries to the knee and lower leg
0.863 0.137 0.000
S02.1 Fracture of base of skull
0.862 0.138 0.000
N30-N39 Other diseases of urinary system
0.858 0.142 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.855 0.145 0.000
N13 Obstructive and reflux uropathy
0.855 0.145 0.000
K76 Other diseases of liver
0.853 0.147 0.000
N17-N19 Renal failure
0.852 0.148 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.851 0.149 0.000
S20-S29 Injuries to the thorax
0.850 0.150 0.000
K75 Other inflammatory liver diseases
0.849 0.151 0.000
U80.1 Methicillin resistant agent
0.847 0.153 0.000
I61 Intracerebral haemorrhage
0.847 0.153 0.000
I51.8 Other ill-defined heart diseases
0.847 0.153 0.000
Q00-Q07 Congenital malformations of the nervous system
0.847 0.153 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.841 0.159 0.000
S06.2 Diffuse brain injury
0.838 0.161 0.000
Q60-Q64 Congenital malformations of the urinary system
0.838 0.162 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.838 0.162 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.838 0.162 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.836 0.164 0.000
D50-D53 Nutritional anaemias
0.834 0.166 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.832 0.168 0.000
N32 Other disorders of bladder
0.832 0.168 0.000
K42 Umbilical hernia
0.830 0.170 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.829 0.171 0.000
M54.9 Dorsalgia, unspecified
0.828 0.171 0.000
F30-F39 Mood [affective] disorders
0.828 0.172 0.000
G30-G32 Other degenerative diseases of the nervous system
0.826 0.174 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.826 0.174 0.000
K70.4 Alcoholic hepatic failure
0.823 0.177 0.000
F81 Specific developmental disorders of scholastic skills
0.821 0.179 0.000
K74 Fibrosis and cirrhosis of liver
0.821 0.179 0.000
I30.9 Acute pericarditis, unspecified
0.821 0.179 0.000
M67 Other disorders of synovium and tendon
0.819 0.181 0.000
S02.10 Fracture of base of skull (closed)
0.816 0.184 0.000
M54.57 Low back pain (Lumbosacral region)
0.812 0.188 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.812 0.188 0.000
T90.4 Sequelae of injury of eye and orbit
0.811 0.189 0.000
G83 Other paralytic syndromes
0.809 0.191 0.000
I50.1 Left ventricular failure
0.809 0.191 0.000
M86-M90 Other osteopathies
0.808 0.192 0.000
T92 Sequelae of injuries of upper limb
0.806 0.194 0.000
S06.0 Concussion
0.806 0.194 0.000
M54.22 Cervicalgia (Cervical region)
0.805 0.195 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.805 0.195 0.000
K92 Other diseases of digestive system
0.805 0.195 0.000
F10.4 Withdrawal state with delirium
0.804 0.196 0.000
R26 Abnormalities of gait and mobility
0.804 0.196 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.804 0.196 0.000
F10.3 Withdrawal state
0.801 0.199 0.000
N36 Other disorders of urethra
0.799 0.201 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.798 0.202 0.000
K40 Inguinal hernia
0.795 0.205 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.795 0.205 0.000
D48.1 Connective and other soft tissue
0.794 0.206 0.000
M41 Scoliosis
0.794 0.206 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.793 0.207 0.000
N99-N99 Other disorders of the genitourinary system
0.792 0.208 0.000
K43 Ventral hernia
0.790 0.210 0.000
M54.50 Low back pain (Multiple sites in spine)
0.789 0.211 0.000
N73 Other female pelvic inflammatory diseases
0.789 0.211 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.788 0.212 0.000
Chapter I Certain infectious and parasitic diseases
0.787 0.213 0.000
G82 Paraplegia and tetraplegia
0.786 0.214 0.000
D60-D64 Aplastic and other anaemias
0.786 0.214 0.000
M05-M14 Inflammatory polyarthropathies
0.786 0.214 0.000
T90.5 Sequelae of intracranial injury
0.785 0.215 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.784 0.216 0.000
T90.9 Sequelae of unspecified injury of head
0.784 0.216 0.000
Q80-Q89 Other congenital malformations
0.779 0.221 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.779 0.221 0.000
I46 Cardiac arrest
0.778 0.222 0.000
M70-M79 Other soft tissue disorders
0.778 0.222 0.000
W20-W49 Exposure to inanimate mechanical forces
0.777 0.223 0.000
M54.1 Radiculopathy
0.777 0.223 0.000
T90.1 Sequelae of open wound of head
0.775 0.225 0.000
G95 Other diseases of spinal cord
0.775 0.225 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.773 0.227 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.773 0.227 0.000
N13.8 Other obstructive and reflux uropathy
0.772 0.228 0.000
K73 Chronic hepatitis, not elsewhere classified
0.772 0.228 0.000
V10-V19 Pedal cyclist injured in transport accident
0.772 0.228 0.000
K70.0 Alcoholic fatty liver
0.771 0.229 0.000
F25 Schizoaffective disorders
0.771 0.229 0.000
F22 Persistent delusional disorders
0.771 0.229 0.000
K90 Intestinal malabsorption
0.771 0.229 0.000
K92.1 Melaena
0.771 0.229 0.000
M54.55 Low back pain (Thoracolumbar region)
0.769 0.231 0.000
N32.0 Bladder-neck obstruction
0.769 0.231 0.000
U80.0 Penicillin resistant agent
0.769 0.231 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.768 0.232 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.767 0.233 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.764 0.236 0.000
M54.3 Sciatica
0.763 0.237 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.763 0.237 0.000
I51.4 Myocarditis, unspecified
0.763 0.237 0.000
M00-M03 Infectious arthropathies
0.762 0.238 0.000
I60 Subarachnoid haemorrhage
0.761 0.239 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.760 0.240 0.000
H21 Other disorders of iris and ciliary body
0.760 0.240 0.000
K76.6 Portal hypertension
0.758 0.242 0.000
D46 Myelodysplastic syndromes
0.758 0.242 0.000
S90-S99 Injuries to the ankle and foot
0.757 0.243 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.756 0.243 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.753 0.247 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.753 0.247 0.000
G43 Migraine
0.752 0.248 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.751 0.248 0.000
G47.8 Other sleep disorders
0.750 0.250 0.000
M60-M63 Disorders of muscles
0.750 0.250 0.000
G80 Infantile cerebral palsy
0.748 0.252 0.000
K70.3 Alcoholic cirrhosis of liver
0.747 0.253 0.000
F11 Mental and behavioural disorders due to use of opioids
0.747 0.253 0.000
C15-C26 Malignant neoplasms of digestive organs
0.746 0.254 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.745 0.255 0.000
K72 Hepatic failure, not elsewhere classified
0.745 0.255 0.000
F10.1 Harmful use
0.745 0.255 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.745 0.255 0.000
N73.6 Female pelvic peritoneal adhesions
0.745 0.255 0.000
M51 Other intervertebral disk disorders
0.744 0.256 0.000
H40.8 Other glaucoma
0.744 0.256 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.744 0.256 0.000
D68 Other coagulation defects
0.743 0.257 0.000
Y86 Sequelae of other accidents
0.743 0.257 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.743 0.257 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.743 0.257 0.000
N18 Chronic renal failure
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.741 0.259 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.741 0.259 0.000
S02.6 Fracture of mandible
0.741 0.259 0.000
M93 Other osteochondropathies
0.741 0.259 0.000
S09 Other and unspecified injuries of head
0.740 0.260 0.000
I44.7 Left bundle-branch block, unspecified
0.740 0.260 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.740 0.260 0.000
Q50-Q56 Congenital malformations of genital organs
0.739 0.261 0.000
S27 Injury of other and unspecified intrathoracic organs
0.738 0.262 0.000
S02.7 Multiple fractures involving skull and facial bones
0.738 0.262 0.000
I45 Other conduction disorders
0.738 0.262 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.737 0.263 0.000
R50-R69 General symptoms and signs
0.737 0.263 0.000
S01 Open wound of head
0.737 0.263 0.000
G47.4 Narcolepsy and cataplexy
0.734 0.266 0.000
C60-C63 Malignant neoplasms of male genital organs
0.732 0.268 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.731 0.268 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.730 0.270 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.730 0.270 0.000
I51.0 Cardiac septal defect, acquired
0.728 0.272 0.000
N13.3 Other and unspecified hydronephrosis
0.728 0.272 0.000
U51 Admission status on psychiatric patients
0.728 0.272 0.000
K76.9 Liver disease, unspecified
0.726 0.274 0.000
F31 Bipolar affective disorder
0.726 0.274 0.000
M54.6 Pain in thoracic spine
0.726 0.274 0.000
N70 Salpingitis and oophoritis
0.726 0.274 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.725 0.274 0.000
Q07 Other congenital malformations of nervous system
0.725 0.275 0.000
Y95 Nosocomial condition
0.725 0.275 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.725 0.275 0.000
N32.3 Diverticulum of bladder
0.725 0.275 0.000
R50 Fever of unknown origin
0.724 0.276 0.000
M92 Other juvenile osteochondrosis
0.724 0.276 0.000
S06.3 Focal brain injury
0.724 0.276 0.000
F60-F69 Disorders of adult personality and behaviour
0.723 0.277 0.000
S89 Other and unspecified injuries of lower leg
0.723 0.277 0.000
K70.1 Alcoholic hepatitis
0.722 0.278 0.000
M53 Other dorsopathies, not elsewhere classified
0.722 0.278 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.722 0.278 0.000
M54.4 Lumbago with sciatica
0.722 0.278 0.000
M41.9 Scoliosis, unspecified
0.722 0.278 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.721 0.279 0.000
I27 Other pulmonary heart diseases
0.721 0.279 0.000
N32.8 Other specified disorders of bladder
0.720 0.280 0.000
I05-I09 Chronic rheumatic heart diseases
0.717 0.283 0.000
Q61 Cystic kidney disease
0.717 0.283 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
M54.8 Other dorsalgia
0.716 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.716 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.716 0.284 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.716 0.284 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.716 0.284 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.716 0.284 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.716 0.284 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.716 0.284 0.000
M54.54 Low back pain-Thoracic
0.716 0.284 0.000
M54.53 Low back pain-Cervicothoracic
0.716 0.284 0.000
M54.52 Low back pain-Cervical
0.716 0.284 0.000
M54.51 Low back pain-Occipit-atl-axl
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
F10.9 Unspecified mental and behavioural disorder
0.715 0.285 0.000
F10.8 Other mental and behavioural disorders
0.715 0.285 0.000
F10.7 Residual and late-onset psychotic disorder
0.715 0.285 0.000
F10.6 Amnesic syndrome
0.715 0.285 0.000
F10.5 Psychotic disorder
0.715 0.285 0.000
T93 Sequelae of injuries of lower limb
0.715 0.285 0.000
S05 Injury of eye and orbit
0.714 0.286 0.000
R50.9 Fever, unspecified
0.714 0.286 0.000
H55-H59 Other disorders of eye and adnexa
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
N17 Acute renal failure
0.713 0.287 0.000
N13.4 Hydroureter
0.712 0.287 0.000
S02.0 Fracture of vault of skull
0.712 0.287 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.288 0.000
R52 Pain, not elsewhere classified
0.711 0.289 0.000
G93 Other disorders of brain
0.711 0.289 0.000
H40.0 Glaucoma suspect
0.710 0.290 0.000
C81 Hodgkin's disease
0.710 0.290 0.000
K75.9 Inflammatory liver disease, unspecified
0.710 0.290 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.710 0.290 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
K77 Liver disorders in diseases classified elsewhere
0.709 0.291 0.000
K71 Toxic liver disease
0.709 0.291 0.000
M43 Other deforming dorsopathies
0.709 0.291 0.000
F33 Recurrent depressive disorder
0.708 0.292 0.000
D00-D09 In situ neoplasms
0.707 0.292 0.000
S06.00 Concussion (without open intracranial wound)
0.707 0.293 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.707 0.293 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.706 0.294 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.706 0.294 0.000
I44.1 Atrioventricular block, second degree
0.706 0.294 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.706 0.294 0.000
Q35-Q37 Cleft lip and cleft palate
0.706 0.294 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.706 0.294 0.000
S06.5 Traumatic subdural haemorrhage
0.704 0.296 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.703 0.296 0.000
S07 Crushing injury of head
0.703 0.296 0.000
S04 Injury of cranial nerves
0.703 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.703 0.296 0.000
B25-B34 Other viral diseases
0.703 0.297 0.000
D51 Vitamin B12 deficiency anaemia
0.703 0.297 0.000
I50.9 Heart failure, unspecified
0.702 0.298 0.000
M66 Spontaneous rupture of synovium and tendon
0.701 0.299 0.000
I51.6 Cardiovascular disease, unspecified
0.701 0.299 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
G44 Other headache syndromes
0.699 0.301 0.000
C90.0 Multiple myeloma
0.699 0.301 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.699 0.301 0.000
H42 Glaucoma in diseases classified elsewhere
0.697 0.302 0.000
H53-H54 Visual disturbances and blindness
0.697 0.303 0.000
H40.6 Glaucoma secondary to drugs
0.697 0.303 0.000
H40.4 Glaucoma secondary to eye inflammation
0.697 0.303 0.000
H40.3 Glaucoma secondary to eye trauma
0.697 0.303 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.697 0.303 0.000
Q78 Other osteochondrodysplasias
0.697 0.303 0.000
K74.6 Other and unspecified cirrhosis of liver
0.696 0.304 0.000
C71 Malignant neoplasm of brain
0.696 0.304 0.000
I42 Cardiomyopathy
0.696 0.304 0.000
G47.3 Sleep apnoea
0.696 0.304 0.000
F29 Unspecified nonorganic psychosis
0.695 0.305 0.000
I51.5 Myocardial degeneration
0.695 0.305 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.695 0.305 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.695 0.305 0.000
K50-K52 Noninfective enteritis and colitis
0.695 0.305 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.695 0.305 0.000
G81 Hemiplegia
0.694 0.306 0.000
T98 Sequelae of other and unspecified effects of external causes
0.694 0.306 0.000
T95 Sequelae of burns, corrosions and frostbite
0.694 0.306 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.694 0.306 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.694 0.306 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.694 0.306 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.693 0.306 0.000
C69 Malignant neoplasm of eye and adnexa
0.693 0.307 0.000
K65-K67 Diseases of peritoneum
0.693 0.307 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.692 0.308 0.000
G41 Status epilepticus
0.692 0.308 0.000
I36 Nonrheumatic tricuspid valve disorders
0.692 0.308 0.000
S80 Superficial injury of lower leg
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
I62 Other nontraumatic intracranial haemorrhage
0.689 0.311 0.000
D50 Iron deficiency anaemia
0.688 0.312 0.000
K46 Unspecified abdominal hernia
0.688 0.312 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.688 0.312 0.000
N36.2 Urethral caruncle
0.687 0.312 0.000
R56 Convulsions, not elsewhere classified
0.687 0.313 0.000
H18 Other disorders of cornea
0.687 0.313 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.687 0.313 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.686 0.314 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.685 0.315 0.000
H10-H13 Disorders of conjunctiva
0.685 0.315 0.000
M67.8 Other specified disorders of synovium and tendon
0.684 0.316 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.684 0.316 0.000
B15-B19 Viral hepatitis
0.684 0.316 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.684 0.316 0.000
S10-S19 Injuries to the neck
0.683 0.316 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.683 0.317 0.000
I61.8 Other intracerebral haemorrhage
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.682 0.317 0.000
V80-V89 Other land transport accidents
0.682 0.318 0.000
M89 Other disorders of bone
0.681 0.319 0.000
R27 Other lack of coordination
0.680 0.320 0.000
E70-E90 Metabolic disorders
0.680 0.320 0.000
S81 Open wound of lower leg
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.321 0.000
X50-X57 Overexertion, travel and privation
0.679 0.321 0.000
H21.8 Other specified disorders of iris and ciliary body
0.679 0.321 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.679 0.321 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.679 0.321 0.000
S72 Fracture of femur
0.678 0.322 0.000
G82.2 Paraplegia, unspecified
0.678 0.322 0.000
Y85 Sequelae of transport accidents
0.678 0.322 0.000
I51.9 Heart disease, unspecified
0.678 0.322 0.000
G47.2 Disorders of the sleep-wake schedule
0.677 0.322 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.677 0.323 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.676 0.324 0.000
S06.8 Other intracranial injuries
0.676 0.324 0.000
S06.9 Intracranial injury, unspecified
0.676 0.324 0.000
S06.7 Intracranial injury with prolonged coma
0.676 0.324 0.000
S06.4 Epidural haemorrhage
0.676 0.324 0.000
S06.1 Traumatic cerebral oedema
0.676 0.324 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.676 0.324 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.675 0.325 0.000
S50-S59 Injuries to the elbow and forearm
0.675 0.325 0.000
D55-D59 Haemolytic anaemias
0.674 0.326 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.674 0.326 0.000
K45 Other abdominal hernia
0.674 0.326 0.000
I35 Nonrheumatic aortic valve disorders
0.673 0.327 0.000
T90.8 Sequelae of other specified injuries of head
0.673 0.327 0.000
T90.3 Sequelae of injury of cranial nerves
0.673 0.327 0.000
T90.0 Sequelae of superficial injury of head
0.673 0.327 0.000
N36.3 Prolapsed urethral mucosa
0.673 0.327 0.000
F25.9 Schizoaffective disorder, unspecified
0.672 0.327 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.672 0.328 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.672 0.328 0.000
F22.0 Delusional disorder
0.672 0.328 0.000
I85 Oesophageal varices
0.671 0.329 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.670 0.330 0.000
M94 Other disorders of cartilage
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.669 0.331 0.000
N76 Other inflammation of vagina and vulva
0.669 0.331 0.000
R87 Abnormal findings in specimens from female genital organs
0.669 0.331 0.000
K75.8 Other specified inflammatory liver diseases
0.668 0.332 0.000
S01.9 Open wound of head, part unspecified
0.668 0.332 0.000
S02.8 Fractures of other skull and facial bones
0.668 0.332 0.000
G90 Disorders of autonomic nervous system
0.668 0.332 0.000
I44.6 Other and unspecified fascicular block
0.667 0.333 0.000
M95.0 Acquired deformity of nose
0.667 0.333 0.000
S02.4 Fracture of malar and maxillary bones
0.666 0.334 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.666 0.334 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.664 0.335 0.000
S02.3 Fracture of orbital floor
0.664 0.335 0.000
N70.1 Chronic salpingitis and oophoritis
0.663 0.337 0.000
G83.4 Cauda equina syndrome
0.663 0.337 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.663 0.337 0.000
R26.0 Ataxic gait
0.663 0.337 0.000
C17 Malignant neoplasm of small intestine
0.663 0.337 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.663 0.337 0.000
M10 Gout
0.663 0.337 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.662 0.338 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.661 0.338 0.000
U50 Level of care administered to neonates
0.661 0.338 0.000
U07 Emergency use of U07
0.661 0.338 0.000
U06 Emergency use of U06
0.661 0.338 0.000
U04 Severe acute respiratory syndrome [SARS]
0.661 0.338 0.000
U52 First in a series of a regular day/night admissions
0.661 0.338 0.000
S86 Injury of muscle and tendon at lower leg level
0.661 0.339 0.000
I10-I15 Hypertensive diseases
0.661 0.339 0.000
G30 Alzheimer's disease
0.661 0.339 0.000
T91 Sequelae of injuries of neck and trunk
0.661 0.339 0.000
E20-E35 Disorders of other endocrine glands
0.661 0.339 0.000
M45-M49 Spondylopathies
0.660 0.340 0.000
Q28 Other congenital malformations of circulatory system
0.659 0.341 0.000
H40.5 Glaucoma secondary to other eye disorders
0.658 0.341 0.000
C62 Malignant neoplasm of testis
0.658 0.342 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.658 0.342 0.000
N00-N08 Glomerular diseases
0.658 0.342 0.000
N13.6 Pyonephrosis
0.657 0.343 0.000
Y35-Y36 Legal intervention and operations of war
0.657 0.343 0.000
Y10-Y34 Event of undetermined intent
0.657 0.343 0.000
X85-X99 Assault
0.657 0.343 0.000
X30-X39 Exposure to forces of nature
0.657 0.343 0.000
X20-X29 Contact with venomous animals and plants
0.657 0.343 0.000
X10-X19 Contact with heat and hot substances
0.657 0.343 0.000
X00-X09 Exposure to smoke, fire and flames
0.657 0.343 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.657 0.343 0.000
W75-W84 Other accidental threats to breathing
0.657 0.343 0.000
W65-W74 Accidental drowning and submersion
0.657 0.343 0.000
W50-W64 Exposure to animate mechanical forces
0.657 0.343 0.000
V98-V99 Other and unspecified transport accidents
0.657 0.343 0.000
V95-V97 Air and space transport accidents
0.657 0.343 0.000
V90-V94 Water transport accidents
0.657 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.657 0.343 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.657 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.657 0.343 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.657 0.343 0.000
V01-V09 Pedestrian injured in transport accident
0.657 0.343 0.000
S01.1 Open wound of eyelid and periocular area
0.657 0.343 0.000
F80 Specific developmental disorders of speech and language
0.657 0.343 0.000
C50-C50 Malignant neoplasm of breast
0.656 0.344 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.656 0.344 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.656 0.344 0.000
N18.5 Chronic kidney disease, stage 5
0.656 0.344 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.653 0.347 0.000
H17 Corneal scars and opacities
0.653 0.347 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.653 0.347 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.653 0.347 0.000
F23 Acute and transient psychotic disorders
0.652 0.348 0.000
F28 Other nonorganic psychotic disorders
0.652 0.348 0.000
F24 Induced delusional disorder
0.652 0.348 0.000
F21 Schizotypal disorder
0.652 0.348 0.000
N71 Inflammatory disease of uterus, except cervix
0.652 0.348 0.000
Q05 Spina bifida
0.652 0.348 0.000
R56.8 Other and unspecified convulsions
0.651 0.349 0.000
D68.8 Other specified coagulation defects
0.651 0.349 0.000
T14 Injury of unspecified body region
0.651 0.349 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.651 0.349 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.651 0.349 0.000
G91 Hydrocephalus
0.650 0.349 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.650 0.350 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.650 0.350 0.000
E83 Disorders of mineral metabolism
0.650 0.350 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.650 0.350 0.000
K75.0 Abscess of liver
0.650 0.350 0.000
M77 Other enthesopathies
0.649 0.351 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.351 0.000
D68.9 Coagulation defect, unspecified
0.648 0.352 0.000
D48.7 Other specified sites
0.648 0.352 0.000
Q65 Congenital deformities of hip
0.647 0.353 0.000
F00 Dementia in Alzheimer's disease
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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