TreeWAS – Variant ID: rs117250828

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter II Neoplasms	0.999	0.001
I20-I25 Ischaemic heart diseases	0.998	0.002
I25 Chronic ischaemic heart disease	0.997	0.003
D10-D36 Benign neoplasms	0.996	0.004
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
I25.9 Chronic ischaemic heart disease, unspecified	0.984	0.016
D25 Leiomyoma of uterus	0.979	0.021
M20-M25 Other joint disorders	0.968	0.032
D25.9 Leiomyoma of uterus, unspecified	0.965	0.035
I30-I52 Other forms of heart disease	0.948	0.052
I25.1 Atherosclerotic heart disease	0.947	0.053
M15-M19 Arthrosis	0.941	0.059
Chapter XI Diseases of the digestive system	0.935	0.065
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.910	0.090
M23 Internal derangement of knee	0.909	0.091
M17 Gonarthrosis [arthrosis of knee]	0.901	0.099
K55-K64 Other diseases of intestines	0.882	0.118
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.879	0.121
K63 Other diseases of intestine	0.870	0.130
Chapter XV Pregnancy, childbirth and the puerperium	0.868	0.132
I20 Angina pectoris	0.863	0.137
Chapter VI Diseases of the nervous system	0.861	0.138
K63.5 Polyp of colon	0.860	0.140
I51 Complications and ill-defined descriptions of heart disease	0.856	0.144
Chapter XII Diseases of the skin and subcutaneous tissue	0.851	0.149
D12.5 Sigmoid colon	0.847	0.153
M17.9 Gonarthrosis, unspecified	0.846	0.154
I25.2 Old myocardial infarction	0.843	0.157
Chapter XX External causes of morbidity and mortality	0.831	0.168
C15-C26 Malignant neoplasms of digestive organs	0.827	0.173
Chapter VIII Diseases of the ear and mastoid process	0.826	0.174
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.821	0.179
M20 Acquired deformities of fingers and toes	0.819	0.181
M23.3 Other meniscus derangements	0.818	0.182
Chapter VII Diseases of the eye and adnexa	0.817	0.183
K80 Cholelithiasis	0.816	0.184
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.809	0.191
D23 Other benign neoplasms of skin	0.807	0.193
D12.4 Descending colon	0.804	0.196
I25.8 Other forms of chronic ischaemic heart disease	0.796	0.204
I51.7 Cardiomegaly	0.792	0.208
M05-M14 Inflammatory polyarthropathies	0.790	0.210
M23.2 Derangement of meniscus due to old tear or injury	0.789	0.211
M80-M85 Disorders of bone density and structure	0.789	0.211
D17 Benign lipomatous neoplasm	0.783	0.217
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.783	0.217
I20.9 Angina pectoris, unspecified	0.780	0.220
C51-C58 Malignant neoplasms of female genital organs	0.778	0.222
D22 Melanocytic naevi	0.776	0.224
I50 Heart failure	0.774	0.226
I60-I69 Cerebrovascular diseases	0.773	0.227
G40-G47 Episodic and paroxysmal disorders	0.771	0.229
M31 Other necrotising vasculopathies	0.768	0.232
I24 Other acute ischaemic heart diseases	0.763	0.236
I44 Atrioventricular and left bundle-branch block	0.762	0.238
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.761	0.239
I05-I09 Chronic rheumatic heart diseases	0.759	0.241
D18 Haemangioma and lymphangioma, any site	0.756	0.244
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.755	0.245
Chapter XXI Factors influencing health status and contact with health services	0.755	0.245
D25.0 Submucous leiomyoma of uterus	0.751	0.249
C60-C63 Malignant neoplasms of male genital organs	0.750	0.250
K35-K38 Diseases of appendix	0.747	0.253
M17.1 Other primary gonarthrosis	0.746	0.254
O60-O75 Complications of labour and delivery	0.745	0.255
Chapter X Diseases of the respiratory system	0.740	0.260
M25 Other joint disorders, not elsewhere classified	0.739	0.261
I42 Cardiomyopathy	0.738	0.261
C43-C44 Melanoma and other malignant neoplasms of skin	0.738	0.262
M45-M49 Spondylopathies	0.733	0.267
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.732	0.268
D12.3 Transverse colon	0.726	0.274
K70-K77 Diseases of liver	0.723	0.277
M50-M54 Other dorsopathies	0.718	0.281
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.716	0.284
I45 Other conduction disorders	0.716	0.284
D37-D48 Neoplasms of uncertain or unknown behaviour	0.716	0.284
D00-D09 In situ neoplasms	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.716	0.284
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.716	0.284
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.284
I23 Certain current complications following acute myocardial infarction	0.716	0.284
I22 Subsequent myocardial infarction	0.716	0.284
M40-M43 Deforming dorsopathies	0.715	0.285
I25.6 Silent myocardial ischaemia	0.715	0.285
I25.5 Ischaemic cardiomyopathy	0.715	0.285
I25.4 Coronary artery aneurysm	0.715	0.285
I25.3 Aneurysm of heart	0.715	0.285
I25.0 Atherosclerotic cardiovascular disease, so described	0.715	0.285
D36 Benign neoplasm of other and unspecified sites	0.714	0.286
D35 Benign neoplasm of other and unspecified endocrine glands	0.714	0.286
D33 Benign neoplasm of brain and other parts of central nervous system	0.714	0.286
D32 Benign neoplasm of meninges	0.714	0.286
D31 Benign neoplasm of eye and adnexa	0.714	0.286
D30 Benign neoplasm of urinary organs	0.714	0.286
D29 Benign neoplasm of male genital organs	0.714	0.286
D28 Benign neoplasm of other and unspecified female genital organs	0.714	0.286
D26 Other benign neoplasms of uterus	0.714	0.286
D21 Other benign neoplasms of connective and other soft tissue	0.714	0.286
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.714	0.286
D19 Benign neoplasm of mesothelial tissue	0.714	0.286
D16 Benign neoplasm of bone and articular cartilage	0.714	0.286
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.714	0.286
D14 Benign neoplasm of middle ear and respiratory system	0.714	0.286
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.714	0.286
D11 Benign neoplasm of major salivary glands	0.714	0.286
D10 Benign neoplasm of mouth and pharynx	0.714	0.286
D34 Benign neoplasm of thyroid gland	0.714	0.286
D24 Benign neoplasm of breast	0.714	0.286
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.714	0.286
M91-M94 Chondropathies	0.714	0.286
M86-M90 Other osteopathies	0.714	0.286
M65-M68 Disorders of synovium and tendon	0.714	0.286
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
K80.2 Calculus of gallbladder without cholecystitis	0.712	0.288
I83 Varicose veins of lower extremities	0.712	0.288
Chapter IV Endocrine, nutritional and metabolic diseases	0.707	0.293
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.705	0.295
M18 Arthrosis of first carpometacarpal joint	0.704	0.296
K80.1 Calculus of gallbladder with other cholecystitis	0.703	0.297
D25.2 Subserosal leiomyoma of uterus	0.702	0.298
D25.1 Intramural leiomyoma of uterus	0.702	0.298
L80-L99 Other disorders of the skin and subcutaneous tissue	0.702	0.298
I47 Paroxysmal tachycardia	0.701	0.299
K65-K67 Diseases of peritoneum	0.701	0.299
M23.30 Other meniscus derangements (Multiple sites)	0.700	0.300
D27 Benign neoplasm of ovary	0.696	0.304
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.694	0.306
M35 Other systemic involvement of connective tissue	0.694	0.306
M34 Systemic sclerosis	0.694	0.306
M33 Dermatopolymyositis	0.694	0.306
M32 Systemic lupus erythematosus	0.694	0.306
M30 Polyarteritis nodosa and related conditions	0.694	0.306
M24 Other specific joint derangements	0.694	0.306
M22 Disorders of patella	0.694	0.306
M21 Other acquired deformities of limbs	0.694	0.306
G47 Sleep disorders	0.693	0.306
K81 Cholecystitis	0.690	0.310
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.686	0.314
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.686	0.314
K83 Other diseases of biliary tract	0.685	0.315
Chapter V Mental and behavioural disorders	0.683	0.317
I70-I79 Diseases of arteries, arterioles and capillaries	0.682	0.317
C20 Malignant neoplasm of rectum	0.681	0.319
K90-K93 Other diseases of the digestive system	0.681	0.319
M17.0 Primary gonarthrosis, bilateral	0.680	0.320
H40-H42 Glaucoma	0.680	0.320
I52 Other heart disorders in diseases classified elsewhere	0.679	0.320
I49 Other cardiac arrhythmias	0.679	0.320
I48 Atrial fibrillation and flutter	0.679	0.320
I46 Cardiac arrest	0.679	0.320
I43 Cardiomyopathy in diseases classified elsewhere	0.679	0.320
I41 Myocarditis in diseases classified elsewhere	0.679	0.320
I40 Acute myocarditis	0.679	0.320
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.679	0.320
I37 Pulmonary valve disorders	0.679	0.320
I36 Nonrheumatic tricuspid valve disorders	0.679	0.320
I35 Nonrheumatic aortic valve disorders	0.679	0.320
I33 Acute and subacute endocarditis	0.679	0.320
I32 Pericarditis in diseases classified elsewhere	0.679	0.320
I31 Other diseases of pericardium	0.679	0.320
I30 Acute pericarditis	0.679	0.320
I38 Endocarditis, valve unspecified	0.679	0.320
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.676	0.324
M15 Polyarthrosis	0.675	0.325
M20.1 Hallux valgus (acquired)	0.673	0.327
D23.6 Skin of upper limb, including shoulder	0.672	0.328
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.671	0.329
C64-C68 Malignant neoplasms of urinary tract	0.671	0.329
M19 Other arthrosis	0.671	0.329
L00-L08 Infections of the skin and subcutaneous tissue	0.670	0.330
I95-I99 Other and unspecified disorders of the circulatory system	0.665	0.335
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.660	0.340
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.660	0.340
M16 Coxarthrosis [arthrosis of hip]	0.659	0.341
L60-L75 Disorders of skin appendages	0.658	0.342
K56 Paralytic ileus and intestinal obstruction without hernia	0.653	0.347
H65-H75 Diseases of middle ear and mastoid	0.652	0.348
D12.9 Anus and anal canal	0.652	0.348
D12.7 Rectosigmoid junction	0.652	0.348
D12.1 Appendix	0.652	0.348
M23.9 Internal derangement of knee, unspecified	0.652	0.348
M23.8 Other internal derangements of knee	0.652	0.348
M23.6 Other spontaneous disruption of ligament(s) of knee	0.652	0.348
M23.5 Chronic instability of knee	0.652	0.348
M23.4 Loose body in knee	0.652	0.348
M23.1 Discoid meniscus (congenital)	0.652	0.348
M23.0 Cystic meniscus	0.652	0.348
I20.8 Other forms of angina pectoris	0.651	0.349
K63.8 Other specified diseases of intestine	0.649	0.351
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.649	0.351
H53-H54 Visual disturbances and blindness	0.648	0.351
M70-M79 Other soft tissue disorders	0.648	0.352
M17.5 Other secondary gonarthrosis	0.646	0.354
M17.4 Other secondary gonarthrosis, bilateral	0.646	0.354
M17.3 Other posttraumatic gonarthrosis	0.646	0.354
M17.2 Posttraumatic gonarthrosis, bilateral	0.646	0.354
I44.1 Atrioventricular block, second degree	0.642	0.358
K58 Irritable bowel syndrome	0.641	0.359
M81 Osteoporosis without pathological fracture	0.641	0.359
C56 Malignant neoplasm of ovary	0.640	0.360
K61 Abscess of anal and rectal regions	0.640	0.360
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.639	0.361
H90-H95 Other disorders of ear	0.636	0.364
M20.5 Other deformities of toe(s) (acquired)	0.635	0.364
G47.3 Sleep apnoea	0.634	0.365
J20-J22 Other acute lower respiratory infections	0.634	0.366
G50-G59 Nerve, nerve root and plexus disorders	0.634	0.366
O80-O84 Delivery	0.632	0.367
K64 Haemorrhoids and perianal venous thrombosis	0.632	0.368
K55 Vascular disorders of intestine	0.632	0.368
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.632	0.368
M06 Other rheumatoid arthritis	0.630	0.369
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.630	0.370
K86 Other diseases of pancreas	0.630	0.370
K85 Acute pancreatitis	0.630	0.370
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.629	0.370
O94-O99 Other obstetric conditions, not elsewhere classified	0.629	0.371
C18 Malignant neoplasm of colon	0.628	0.372
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.627	0.373
D22.3 Melanocytic naevi of other and unspecified parts of face	0.626	0.374
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.625	0.375
M31.6 Other giant cell arteritis	0.624	0.375
K63.9 Disease of intestine, unspecified	0.623	0.376
K63.4 Enteroptosis	0.623	0.376
K63.3 Ulcer of intestine	0.623	0.376
K63.2 Fistula of intestine	0.623	0.376
K63.1 Perforation of intestine (nontraumatic)	0.623	0.376
K63.0 Abscess of intestine	0.623	0.376
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.623	0.377
O85-O92 Complications predominantly related to the puerperium	0.622	0.377
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.622	0.378
G80-G83 Cerebral palsy and other paralytic syndromes	0.622	0.378
O00-O08 Pregnancy with abortive outcome	0.621	0.379
Chapter XIV Diseases of the genitourinary system	0.621	0.379
I50.9 Heart failure, unspecified	0.621	0.379
H80-H83 Diseases of inner ear	0.620	0.379
D12.0 Caecum	0.619	0.380
I20.1 Angina pectoris with documented spasm	0.619	0.381
I50.0 Congestive heart failure	0.618	0.382
O20-O29 Other maternal disorders predominantly related to pregnancy	0.618	0.382
G70-G73 Diseases of myoneural junction and muscle	0.618	0.382
G30-G32 Other degenerative diseases of the nervous system	0.618	0.382
G20-G26 Extrapyramidal and movement disorders	0.618	0.382
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.618	0.382
G00-G09 Inflammatory diseases of the central nervous system	0.618	0.382
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.617	0.383
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.616	0.384
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.616	0.384
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.616	0.384
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.614	0.386
I51.9 Heart disease, unspecified	0.613	0.386
I51.6 Cardiovascular disease, unspecified	0.613	0.386
I51.5 Myocardial degeneration	0.613	0.386
I51.4 Myocarditis, unspecified	0.613	0.386
I51.3 Intracardiac thrombosis, not elsewhere classified	0.613	0.386
I51.2 Rupture of papillary muscle, not elsewhere classified	0.613	0.386
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.613	0.386
I51.0 Cardiac septal defect, acquired	0.613	0.386
K35 Acute appendicitis	0.612	0.388
M25.7 Osteophyte	0.611	0.389
M20.4 Other hammer toe(s) (acquired)	0.611	0.389
G90-G99 Other disorders of the nervous system	0.611	0.389
L50-L54 Urticaria and erythema	0.610	0.390
L40-L45 Papulosquamous disorders	0.610	0.390
L20-L30 Dermatitis and eczema	0.610	0.390
L10-L14 Bullous disorders	0.610	0.390
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.610	0.390
K82 Other diseases of gallbladder	0.608	0.392
G40 Epilepsy	0.608	0.392
I51.8 Other ill-defined heart diseases	0.606	0.394
O70 Perineal laceration during delivery	0.603	0.397
C43 Malignant melanoma of skin	0.603	0.397
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.602	0.398
Z00-Z13 Persons encountering health services for examination and investigation	0.599	0.400
O63 Long labour	0.596	0.403
H30-H36 Disorders of choroid and retina	0.596	0.404
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.596	0.404
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.596	0.404
Y60-Y69 Misadventures to patients during surgical and medical care	0.596	0.404
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.596	0.404
Y35-Y36 Legal intervention and operations of war	0.596	0.404
Y10-Y34 Event of undetermined intent	0.596	0.404
Y00-Y09 Assault	0.596	0.404
X85-X99 Assault	0.596	0.404
X60-X84 Intentional self-harm	0.596	0.404
X58-X59 Accidental exposure to other and unspecified factors	0.596	0.404
X50-X57 Overexertion, travel and privation	0.596	0.404
X40-X49 Accidental poisoning by and exposure to noxious substances	0.596	0.404
X30-X39 Exposure to forces of nature	0.596	0.404
X20-X29 Contact with venomous animals and plants	0.596	0.404
X10-X19 Contact with heat and hot substances	0.596	0.404
X00-X09 Exposure to smoke, fire and flames	0.596	0.404
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.596	0.404
W75-W84 Other accidental threats to breathing	0.596	0.404
W65-W74 Accidental drowning and submersion	0.596	0.404
W50-W64 Exposure to animate mechanical forces	0.596	0.404
W20-W49 Exposure to inanimate mechanical forces	0.596	0.404
V98-V99 Other and unspecified transport accidents	0.596	0.404
V95-V97 Air and space transport accidents	0.596	0.404
V90-V94 Water transport accidents	0.596	0.404
V80-V89 Other land transport accidents	0.596	0.404
V70-V79 Bus occupant injured in transport accident	0.596	0.404
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.596	0.404
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.596	0.404
V40-V49 Car occupant injured in transport accident	0.596	0.404
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.596	0.404
V20-V29 Motorcycle rider injured in transport accident	0.596	0.404
V10-V19 Pedal cyclist injured in transport accident	0.596	0.404
V01-V09 Pedestrian injured in transport accident	0.596	0.404
Y83.1 Surgical operation with implant of artificial internal device	0.596	0.404
I24.8 Other forms of acute ischaemic heart disease	0.595	0.405
K57 Diverticular disease of intestine	0.595	0.405
L84 Corns and callosities	0.593	0.407
C26 Malignant neoplasm of other and ill-defined digestive organs	0.593	0.407
C25 Malignant neoplasm of pancreas	0.593	0.407
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.593	0.407
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.593	0.407
C21 Malignant neoplasm of anus and anal canal	0.593	0.407
C17 Malignant neoplasm of small intestine	0.593	0.407
C16 Malignant neoplasm of stomach	0.593	0.407
C15 Malignant neoplasm of oesophagus	0.593	0.407
C23 Malignant neoplasm of gallbladder	0.593	0.407
C19 Malignant neoplasm of rectosigmoid junction	0.593	0.407
C50-C50 Malignant neoplasm of breast	0.593	0.407
M10 Gout	0.593	0.407
H60-H62 Diseases of external ear	0.592	0.407
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.592	0.408
C34 Malignant neoplasm of bronchus and lung	0.591	0.409
S40-S49 Injuries to the shoulder and upper arm	0.590	0.410
I44.2 Atrioventricular block, complete	0.589	0.411
C80 Malignant neoplasm without specification of site	0.589	0.411
C76 Malignant neoplasm of other and ill-defined sites	0.589	0.411
I42.9 Cardiomyopathy, unspecified	0.589	0.411
Chapter I Certain infectious and parasitic diseases	0.588	0.412
M20.6 Acquired deformity of toe(s), unspecified	0.587	0.413
M20.3 Other deformity of hallux (acquired)	0.587	0.413
M20.0 Deformity of finger(s)	0.587	0.413
I08 Multiple valve diseases	0.587	0.413
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.586	0.414
M23.37 Other meniscus derangements-Capsular lig	0.586	0.414
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.586	0.414
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.586	0.414
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.586	0.414
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.586	0.414
H55-H59 Other disorders of eye and adnexa	0.585	0.414
H46-H48 Disorders of optic nerve and visual pathways	0.585	0.414
H43-H45 Disorders of vitreous body and globe	0.585	0.414
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.585	0.414
H10-H13 Disorders of conjunctiva	0.585	0.414
K80.3 Calculus of bile duct with cholangitis	0.585	0.415
K80.8 Other cholelithiasis	0.585	0.415
K80.4 Calculus of bile duct with cholecystitis	0.585	0.415
K80.0 Calculus of gallbladder with acute cholecystitis	0.585	0.415
I67 Other cerebrovascular diseases	0.584	0.416
D18.0 Haemangioma, any site	0.584	0.416
S80-S89 Injuries to the knee and lower leg	0.582	0.418
H40 Glaucoma	0.582	0.418
M47 Spondylosis	0.581	0.419
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.580	0.420
T79-T79 Certain early complications of trauma	0.580	0.420
T66-T78 Other and unspecified effects of external causes	0.580	0.420
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.580	0.420
T33-T35 Frostbite	0.580	0.420
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.580	0.420
T26-T28 Burns and corrosions confined to eye and internal organs	0.580	0.420
T20-T25 Burns and corrosions of external body surface, specified by site	0.580	0.420
T15-T19 Effects of foreign body entering through natural orifice	0.580	0.420
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.580	0.420
T00-T07 Injuries involving multiple body regions	0.580	0.420
S90-S99 Injuries to the ankle and foot	0.580	0.420
S70-S79 Injuries to the hip and thigh	0.580	0.420
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.580	0.420
S20-S29 Injuries to the thorax	0.580	0.420
S10-S19 Injuries to the neck	0.580	0.420
M20.2 Hallux rigidus	0.580	0.420
C90 Multiple myeloma and malignant plasma cell neoplasms	0.580	0.420
D23.9 Skin, unspecified	0.579	0.421
D23.7 Skin of lower limb, including hip	0.579	0.421
D23.5 Skin of trunk	0.579	0.421
D23.4 Skin of scalp and neck	0.579	0.421
D23.3 Skin of other and unspecified parts of face	0.579	0.421
D23.2 Skin of ear and external auricular canal	0.579	0.421
D23.1 Skin of eyelid, including canthus	0.579	0.421
D23.0 Skin of lip	0.579	0.421
I64 Stroke, not specified as haemorrhage or infarction	0.577	0.423
M54 Dorsalgia	0.575	0.424
G43 Migraine	0.573	0.427
L97 Ulcer of lower limb, not elsewhere classified	0.573	0.427
C61 Malignant neoplasm of prostate	0.571	0.429
K76 Other diseases of liver	0.570	0.430
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.570	0.430
G35-G37 Demyelinating diseases of the central nervous system	0.568	0.431
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.568	0.432
M14 Arthropathies in other diseases classified elsewhere	0.566	0.434
M12 Other specific arthropathies	0.566	0.434
M11 Other crystal arthropathies	0.566	0.434
M09 Juvenile arthritis in diseases classified elsewhere	0.566	0.434
M08 Juvenile arthritis	0.566	0.434
M07 Psoriatic and enteropathic arthropathies	0.566	0.434
M05 Seropositive rheumatoid arthritis	0.566	0.434
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.566	0.434
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.566	0.434
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.566	0.434
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.566	0.434
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.566	0.434
M85 Other disorders of bone density and structure	0.566	0.434
M84 Disorders of continuity of bone	0.566	0.434
M83 Adult osteomalacia	0.566	0.434
M82 Osteoporosis in diseases classified elsewhere	0.566	0.434
M80 Osteoporosis with pathological fracture	0.566	0.434
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.566	0.434
S50-S59 Injuries to the elbow and forearm	0.564	0.436
I47.2 Ventricular tachycardia	0.563	0.436
K65 Peritonitis	0.562	0.438
D17.9 Benign lipomatous neoplasm, unspecified	0.561	0.438
D17.7 Benign lipomatous neoplasm of other sites	0.561	0.438
D17.6 Benign lipomatous neoplasm of spermatic cord	0.561	0.438
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.561	0.438
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.561	0.438
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.561	0.438
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.561	0.438
I88 Nonspecific lymphadenitis	0.561	0.438
I87 Other disorders of veins	0.561	0.438
I86 Varicose veins of other sites	0.561	0.438
I85 Oesophageal varices	0.561	0.438
I82 Other venous embolism and thrombosis	0.561	0.438
I81 Portal vein thrombosis	0.561	0.438
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.561	0.439
I34 Nonrheumatic mitral valve disorders	0.560	0.440
T81 Complications of procedures, not elsewhere classified	0.560	0.440
E00-E07 Disorders of thyroid gland	0.559	0.441
J90-J94 Other diseases of pleura	0.559	0.441
J22 Unspecified acute lower respiratory infection	0.559	0.441
C57 Malignant neoplasm of other and unspecified female genital organs	0.558	0.442
C53 Malignant neoplasm of cervix uteri	0.558	0.442
C51 Malignant neoplasm of vulva	0.558	0.442
C58 Malignant neoplasm of placenta	0.558	0.442
C55 Malignant neoplasm of uterus, part unspecified	0.558	0.442
C52 Malignant neoplasm of vagina	0.558	0.442
K04 Diseases of pulp and periapical tissues	0.558	0.442
O68 Labour and delivery complicated by foetal stress [distress]	0.557	0.442
Y83.8 Other surgical procedures	0.558	0.442
J80-J84 Other respiratory diseases principally affecting the interstitium	0.557	0.443
D22.9 Melanocytic naevi, unspecified	0.556	0.444
D22.7 Melanocytic naevi of lower limb, including hip	0.556	0.444
D22.6 Melanocytic naevi of upper limb, including shoulder	0.556	0.444
D22.4 Melanocytic naevi of scalp and neck	0.556	0.444
D22.2 Melanocytic naevi of ear and external auricular canal	0.556	0.444
D22.1 Melanocytic naevi of eyelid, including canthus	0.556	0.444
D22.0 Melanocytic naevi of lip	0.556	0.444
M13 Other arthritis	0.556	0.444
D12.2 Ascending colon	0.555	0.445
K60 Fissure and fistula of anal and rectal regions	0.555	0.445
S60-S69 Injuries to the wrist and hand	0.555	0.445
I69 Sequelae of cerebrovascular disease	0.554	0.446
I68 Cerebrovascular disorders in diseases classified elsewhere	0.554	0.446
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.554	0.446
I62 Other nontraumatic intracranial haemorrhage	0.554	0.446
I61 Intracerebral haemorrhage	0.554	0.446
I60 Subarachnoid haemorrhage	0.554	0.446
G46 Vascular syndromes of brain in cerebrovascular diseases	0.553	0.447
G44 Other headache syndromes	0.553	0.447
G41 Status epilepticus	0.553	0.447
C78.7 Secondary malignant neoplasm of liver	0.553	0.447
M31.9 Necrotising vasculopathy, unspecified	0.551	0.449
M31.8 Other specified necrotising vasculopathies	0.551	0.449
M31.7 Microscopic polyangiitis	0.551	0.449
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.551	0.449
M31.4 Aortic arch syndrome [Takayasu]	0.551	0.449
M31.3 Wegener's granulomatosis	0.551	0.449
M31.2 Lethal midline granuloma	0.551	0.449
M31.1 Thrombotic microangiopathy	0.551	0.449
M31.0 Hypersensitivity angiitis	0.551	0.449
I45.1 Other and unspecified right bundle-branch block	0.550	0.450
C79 Secondary malignant neoplasm of other sites	0.550	0.450
E10-E14 Diabetes mellitus	0.550	0.450
S00-S09 Injuries to the head	0.549	0.451
T36-T50 Poisoning by drugs, medicaments and biological substances	0.549	0.451
J00-J06 Acute upper respiratory infections	0.548	0.452
I24.9 Acute ischaemic heart disease, unspecified	0.547	0.452
I24.1 Dressler's syndrome	0.547	0.452
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.547	0.452
K83.8 Other specified diseases of biliary tract	0.546	0.454
I44.6 Other and unspecified fascicular block	0.546	0.454
I44.5 Left posterior fascicular block	0.546	0.454
I44.4 Left anterior fascicular block	0.546	0.454
I44.3 Other and unspecified atrioventricular block	0.546	0.454
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.546	0.454
C38 Malignant neoplasm of heart, mediastinum and pleura	0.546	0.454

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations