TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs117262625
log Bayes Factor = 15.8812
Chromosome 8   position 21,089,037  (GRCh37) Explore rs117262625 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Showing all nodes without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
M13 Other arthritis
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.988 0.012 0.000
M13.9 Arthritis, unspecified
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.983 0.017 0.000
M06 Other rheumatoid arthritis
0.981 0.019 0.000
C34 Malignant neoplasm of bronchus and lung
0.979 0.021 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.977 0.023 0.000
R50-R69 General symptoms and signs
0.977 0.023 0.000
R63 Symptoms and signs concerning food and fluid intake
0.975 0.025 0.000
R63.4 Abnormal weight loss
0.973 0.027 0.000
M06.9 Rheumatoid arthritis, unspecified
0.968 0.032 0.000
C34.9 Bronchus or lung, unspecified
0.959 0.041 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.958 0.042 0.000
D10-D36 Benign neoplasms
0.957 0.043 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.954 0.046 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.949 0.051 0.000
M75 Shoulder lesions
0.939 0.061 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.937 0.063 0.000
S80-S89 Injuries to the knee and lower leg
0.936 0.064 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.933 0.067 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.932 0.068 0.000
I60-I69 Cerebrovascular diseases
0.929 0.071 0.000
M20-M25 Other joint disorders
0.928 0.072 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.925 0.075 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.920 0.080 0.000
M50-M54 Other dorsopathies
0.918 0.082 0.000
G81 Hemiplegia
0.916 0.084 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.912 0.088 0.000
Chapter XX External causes of morbidity and mortality
0.912 0.088 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.911 0.089 0.000
Chapter XXI Factors influencing health status and contact with health services
0.911 0.089 0.000
G90-G99 Other disorders of the nervous system
0.909 0.091 0.000
I77 Other disorders of arteries and arterioles
0.906 0.094 0.000
I74 Arterial embolism and thrombosis
0.903 0.097 0.000
S90-S99 Injuries to the ankle and foot
0.899 0.101 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.896 0.104 0.000
G81.9 Hemiplegia, unspecified
0.892 0.108 0.000
M13.94 Arthritis, unspecified (Hand)
0.892 0.108 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.891 0.109 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.890 0.110 0.000
L20-L30 Dermatitis and eczema
0.889 0.111 0.000
C15-C26 Malignant neoplasms of digestive organs
0.888 0.112 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.886 0.114 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.885 0.115 0.000
M75.4 Impingement syndrome of shoulder
0.883 0.117 0.000
Z85 Personal history of malignant neoplasm
0.880 0.120 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.879 0.121 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.878 0.122 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.875 0.125 0.000
D22 Melanocytic naevi
0.872 0.128 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.871 0.129 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.871 0.129 0.000
I70 Atherosclerosis
0.871 0.129 0.000
T81 Complications of procedures, not elsewhere classified
0.869 0.131 0.000
R27 Other lack of coordination
0.866 0.134 0.000
R45 Symptoms and signs involving emotional state
0.866 0.134 0.000
Chapter VIII Diseases of the ear and mastoid process
0.864 0.136 0.000
T66-T78 Other and unspecified effects of external causes
0.863 0.137 0.000
M45-M49 Spondylopathies
0.860 0.140 0.000
I73 Other peripheral vascular diseases
0.860 0.140 0.000
C34.0 Main bronchus
0.852 0.148 0.000
R52 Pain, not elsewhere classified
0.850 0.150 0.000
I69 Sequelae of cerebrovascular disease
0.846 0.153 0.000
Z92 Personal history of medical treatment
0.846 0.154 0.000
M75.0 Adhesive capsulitis of shoulder
0.844 0.156 0.000
M54 Dorsalgia
0.840 0.160 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.840 0.160 0.000
R41.3 Other amnesia
0.840 0.160 0.000
C79 Secondary malignant neoplasm of other sites
0.837 0.163 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.835 0.165 0.000
I77.1 Stricture of artery
0.835 0.165 0.000
C43 Malignant melanoma of skin
0.834 0.166 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.832 0.168 0.000
D22.5 Melanocytic naevi of trunk
0.830 0.170 0.000
S50-S59 Injuries to the elbow and forearm
0.829 0.171 0.000
D24 Benign neoplasm of breast
0.829 0.171 0.000
D23 Other benign neoplasms of skin
0.828 0.172 0.000
G93 Other disorders of brain
0.827 0.173 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.825 0.175 0.000
R21 Rash and other nonspecific skin eruption
0.824 0.176 0.000
S80 Superficial injury of lower leg
0.823 0.177 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.821 0.179 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.820 0.180 0.000
R30-R39 Symptoms and signs involving the urinary system
0.817 0.183 0.000
C18 Malignant neoplasm of colon
0.816 0.184 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.815 0.185 0.000
H90-H95 Other disorders of ear
0.815 0.185 0.000
Z92.3 Personal history of irradiation
0.815 0.185 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.812 0.188 0.000
R53 Malaise and fatigue
0.812 0.188 0.000
Chapter V Mental and behavioural disorders
0.811 0.189 0.000
R56 Convulsions, not elsewhere classified
0.810 0.190 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.810 0.190 0.000
S83.2 Tear of meniscus, current
0.809 0.191 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.807 0.193 0.000
L30 Other dermatitis
0.807 0.193 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.806 0.194 0.000
D32 Benign neoplasm of meninges
0.805 0.195 0.000
M79.0 Rheumatism, unspecified
0.805 0.195 0.000
L85 Other epidermal thickening
0.804 0.196 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.803 0.197 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.801 0.199 0.000
R42 Dizziness and giddiness
0.797 0.203 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.794 0.206 0.000
C18.9 Colon, unspecified
0.789 0.211 0.000
D36 Benign neoplasm of other and unspecified sites
0.788 0.212 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.788 0.212 0.000
R45.1 Restlessness and agitation
0.786 0.214 0.000
G40-G47 Episodic and paroxysmal disorders
0.786 0.214 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.785 0.215 0.000
R26 Abnormalities of gait and mobility
0.785 0.215 0.000
S90 Superficial injury of ankle and foot
0.785 0.215 0.000
R40 Somnolence, stupor and coma
0.783 0.216 0.000
R27.0 Ataxia, unspecified
0.783 0.217 0.000
M51 Other intervertebral disk disorders
0.783 0.217 0.000
L91 Hypertrophic disorders of skin
0.782 0.218 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.781 0.219 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.781 0.219 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
D46 Myelodysplastic syndromes
0.778 0.222 0.000
I72 Other aneurysm
0.777 0.223 0.000
G91 Hydrocephalus
0.775 0.225 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.775 0.225 0.000
C34.3 Lower lobe, bronchus or lung
0.775 0.225 0.000
M13.0 Polyarthritis, unspecified
0.774 0.226 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.774 0.226 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.773 0.227 0.000
I05-I09 Chronic rheumatic heart diseases
0.772 0.228 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.230 0.000
M79.8 Other specified soft tissue disorders
0.770 0.230 0.000
Chapter VII Diseases of the eye and adnexa
0.770 0.230 0.000
C44 Other malignant neoplasms of skin
0.770 0.230 0.000
S10-S19 Injuries to the neck
0.769 0.231 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.768 0.232 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.768 0.232 0.000
M31 Other necrotising vasculopathies
0.767 0.233 0.000
T78 Adverse effects, not elsewhere classified
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
M79.6 Pain in limb
0.765 0.235 0.000
M11 Other crystal arthropathies
0.765 0.235 0.000
L81 Other disorders of pigmentation
0.764 0.236 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.764 0.236 0.000
M24 Other specific joint derangements
0.761 0.239 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.761 0.239 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.760 0.240 0.000
R30 Pain associated with micturition
0.760 0.240 0.000
I62 Other nontraumatic intracranial haemorrhage
0.759 0.241 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.759 0.241 0.000
I67 Other cerebrovascular diseases
0.758 0.242 0.000
I78 Diseases of capillaries
0.758 0.242 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.754 0.246 0.000
M23 Internal derangement of knee
0.754 0.246 0.000
G30-G32 Other degenerative diseases of the nervous system
0.752 0.248 0.000
M86-M90 Other osteopathies
0.751 0.249 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.751 0.249 0.000
M91-M94 Chondropathies
0.750 0.250 0.000
M54.5 Low back pain
0.749 0.251 0.000
C25 Malignant neoplasm of pancreas
0.749 0.251 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.749 0.251 0.000
L30.9 Dermatitis, unspecified
0.748 0.252 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.748 0.252 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.747 0.253 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.746 0.254 0.000
I73.9 Peripheral vascular disease, unspecified
0.744 0.256 0.000
W20-W49 Exposure to inanimate mechanical forces
0.743 0.257 0.000
R52.1 Chronic intractable pain
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.741 0.259 0.000
C60-C63 Malignant neoplasms of male genital organs
0.740 0.260 0.000
R57 Shock, not elsewhere classified
0.739 0.261 0.000
Z98 Other postsurgical states
0.739 0.261 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.739 0.261 0.000
M25 Other joint disorders, not elsewhere classified
0.739 0.261 0.000
R60 Oedema, not elsewhere classified
0.737 0.263 0.000
M21 Other acquired deformities of limbs
0.737 0.263 0.000
M75.3 Calcific tendinitis of shoulder
0.733 0.267 0.000
M79.7 Fibromyalgia
0.732 0.268 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.731 0.269 0.000
S80.9 Superficial injury of lower leg, unspecified
0.731 0.269 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.730 0.269 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.730 0.270 0.000
D23.1 Skin of eyelid, including canthus
0.730 0.270 0.000
M46 Other inflammatory spondylopathies
0.730 0.270 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.730 0.270 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.730 0.270 0.000
M22 Disorders of patella
0.730 0.270 0.000
I61 Intracerebral haemorrhage
0.729 0.271 0.000
L89 Decubitus ulcer
0.729 0.271 0.000
H91 Other hearing loss
0.728 0.272 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.727 0.272 0.000
Z94 Transplanted organ and tissue status
0.727 0.273 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.727 0.273 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.727 0.273 0.000
C43.5 Malignant melanoma of trunk
0.727 0.273 0.000
R41.2 Retrograde amnesia
0.726 0.274 0.000
Z86 Personal history of certain other diseases
0.726 0.274 0.000
C34.1 Upper lobe, bronchus or lung
0.725 0.275 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.724 0.276 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.723 0.277 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.722 0.278 0.000
M80-M85 Disorders of bone density and structure
0.720 0.280 0.000
R30.0 Dysuria
0.720 0.280 0.000
I85 Oesophageal varices
0.720 0.280 0.000
M79.1 Myalgia
0.718 0.282 0.000
G47 Sleep disorders
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
C44.7 Skin of lower limb, including hip
0.715 0.285 0.000
M10 Gout
0.715 0.285 0.000
M05 Seropositive rheumatoid arthritis
0.715 0.285 0.000
D00-D09 In situ neoplasms
0.714 0.286 0.000
E70-E90 Metabolic disorders
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.712 0.288 0.000
G93.9 Disorder of brain, unspecified
0.712 0.288 0.000
M13.8 Other specified arthritis
0.712 0.288 0.000
M13.1 Monoarthritis, not elsewhere classified
0.712 0.288 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.712 0.288 0.000
R73 Elevated blood glucose level
0.711 0.289 0.000
D12.0 Caecum
0.711 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
M45 Ankylosing spondylitis
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.710 0.290 0.000
S00-S09 Injuries to the head
0.709 0.290 0.000
R23 Other skin changes
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.708 0.292 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.708 0.292 0.000
C32 Malignant neoplasm of larynx
0.708 0.292 0.000
C31 Malignant neoplasm of accessory sinuses
0.708 0.292 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.708 0.292 0.000
C37 Malignant neoplasm of thymus
0.708 0.292 0.000
C33 Malignant neoplasm of trachea
0.708 0.292 0.000
M13.93 Arthritis, unspecified (Forearm)
0.708 0.292 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.708 0.292 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.707 0.293 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.707 0.293 0.000
L29 Pruritus
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
M71 Other bursopathies
0.706 0.294 0.000
L50-L54 Urticaria and erythema
0.706 0.294 0.000
G82 Paraplegia and tetraplegia
0.706 0.294 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.706 0.294 0.000
M65-M68 Disorders of synovium and tendon
0.705 0.295 0.000
T86 Failure and rejection of transplanted organs and tissues
0.705 0.295 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
G93.0 Cerebral cysts
0.704 0.296 0.000
R33 Retention of urine
0.703 0.297 0.000
M06.8 Other specified rheumatoid arthritis
0.703 0.297 0.000
M06.4 Inflammatory polyarthropathy
0.703 0.297 0.000
M06.3 Rheumatoid nodule
0.703 0.297 0.000
M06.2 Rheumatoid bursitis
0.703 0.297 0.000
M06.1 Adult-onset Still's disease
0.703 0.297 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.703 0.297 0.000
C34.8 Overlapping lesion of bronchus and lung
0.702 0.298 0.000
C34.2 Middle lobe, bronchus or lung
0.702 0.298 0.000
R25 Abnormal involuntary movements
0.702 0.298 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.702 0.298 0.000
R46 Symptoms and signs involving appearance and behaviour
0.700 0.299 0.000
R43 Disturbances of smell and taste
0.700 0.299 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.700 0.300 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.700 0.300 0.000
R62 Lack of expected normal physiological development
0.700 0.300 0.000
R64 Cachexia
0.700 0.300 0.000
R58 Haemorrhage, not elsewhere classified
0.700 0.300 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.699 0.301 0.000
L90 Atrophic disorders of skin
0.699 0.301 0.000
S92 Fracture of foot, except ankle
0.699 0.301 0.000
H92 Otalgia and effusion of ear
0.699 0.301 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.699 0.301 0.000
M06.0 Seronegative rheumatoid arthritis
0.699 0.301 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.699 0.301 0.000
R63.5 Abnormal weight gain
0.699 0.301 0.000
R63.3 Feeding difficulties and mismanagement
0.699 0.301 0.000
R63.2 Polyphagia
0.699 0.301 0.000
R63.1 Polydipsia
0.699 0.301 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.698 0.301 0.000
M35 Other systemic involvement of connective tissue
0.698 0.302 0.000
S99 Other and unspecified injuries of ankle and foot
0.697 0.302 0.000
D12.2 Ascending colon
0.697 0.303 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.696 0.304 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.694 0.306 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.694 0.306 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.694 0.306 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.694 0.306 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.694 0.306 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.694 0.306 0.000
D60-D64 Aplastic and other anaemias
0.694 0.306 0.000
I89.0 Lymphoedema, not elsewhere classified
0.692 0.308 0.000
I74.5 Embolism and thrombosis of iliac artery
0.691 0.309 0.000
R56.8 Other and unspecified convulsions
0.691 0.309 0.000
M77 Other enthesopathies
0.690 0.310 0.000
S50 Superficial injury of forearm
0.689 0.311 0.000
D12.6 Colon, unspecified
0.689 0.311 0.000
L84 Corns and callosities
0.687 0.313 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.687 0.313 0.000
D31 Benign neoplasm of eye and adnexa
0.686 0.314 0.000
D30 Benign neoplasm of urinary organs
0.686 0.314 0.000
D29 Benign neoplasm of male genital organs
0.686 0.314 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.686 0.314 0.000
D26 Other benign neoplasms of uterus
0.686 0.314 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.686 0.314 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.686 0.314 0.000
D19 Benign neoplasm of mesothelial tissue
0.686 0.314 0.000
D16 Benign neoplasm of bone and articular cartilage
0.686 0.314 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.686 0.314 0.000
D10 Benign neoplasm of mouth and pharynx
0.686 0.314 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.685 0.315 0.000
R47-R49 Symptoms and signs involving speech and voice
0.685 0.315 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.684 0.316 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.684 0.316 0.000
L94 Other localised connective tissue disorders
0.684 0.316 0.000
L93 Lupus erythematosus
0.684 0.316 0.000
L87 Transepidermal elimination disorders
0.684 0.316 0.000
L88 Pyoderma gangrenosum
0.684 0.316 0.000
L86 Keratoderma in diseases classified elsewhere
0.684 0.316 0.000
L83 Acanthosis nigricans
0.684 0.316 0.000
L80 Vitiligo
0.684 0.316 0.000
Z85.6 Personal history of leukaemia
0.684 0.316 0.000
R29.6 Tendency to fall, not elsewhere classified
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.683 0.317 0.000
L28 Lichen simplex chronicus and prurigo
0.683 0.317 0.000
M53 Other dorsopathies, not elsewhere classified
0.683 0.317 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.682 0.318 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.682 0.318 0.000
C44.5 Skin of trunk
0.681 0.319 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.681 0.319 0.000
M07 Psoriatic and enteropathic arthropathies
0.681 0.319 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.681 0.319 0.000
G83 Other paralytic syndromes
0.680 0.320 0.000
G80 Infantile cerebral palsy
0.680 0.320 0.000
G91.9 Hydrocephalus, unspecified
0.679 0.321 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.679 0.321 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.679 0.321 0.000
I63 Cerebral infarction
0.677 0.323 0.000
T81.9 Unspecified complication of procedure
0.676 0.324 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.676 0.324 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.676 0.324 0.000
D23.6 Skin of upper limb, including shoulder
0.676 0.324 0.000
D32.0 Cerebral meninges
0.676 0.324 0.000
M13.98 Arthritis, unspecified (Other)
0.675 0.325 0.000
I86 Varicose veins of other sites
0.674 0.326 0.000
M75.8 Other shoulder lesions
0.674 0.326 0.000
M75.9 Shoulder lesion, unspecified
0.674 0.326 0.000
M75.2 Bicipital tendinitis
0.674 0.326 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.673 0.326 0.000
I70.0 Atherosclerosis of aorta
0.673 0.327 0.000
R27.8 Other and unspecified lack of coordination
0.673 0.327 0.000
M48 Other spondylopathies
0.673 0.327 0.000
S40-S49 Injuries to the shoulder and upper arm
0.673 0.327 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.673 0.327 0.000
D12.5 Sigmoid colon
0.673 0.327 0.000
E86 Volume depletion
0.672 0.328 0.000
S20-S29 Injuries to the thorax
0.672 0.328 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.672 0.328 0.000
M79.9 Soft tissue disorder, unspecified
0.672 0.328 0.000
M79.5 Residual foreign body in soft tissue
0.672 0.328 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.672 0.328 0.000
M79.3 Panniculitis, unspecified
0.672 0.328 0.000
M79.2 Neuralgia and neuritis, unspecified
0.672 0.328 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.672 0.328 0.000
R32 Unspecified urinary incontinence
0.672 0.328 0.000
S89 Other and unspecified injuries of lower leg
0.671 0.329 0.000
S88 Traumatic amputation of lower leg
0.671 0.329 0.000
S87 Crushing injury of lower leg
0.671 0.329 0.000
S86 Injury of muscle and tendon at lower leg level
0.671 0.329 0.000
S85 Injury of blood vessels at lower leg level
0.671 0.329 0.000
S84 Injury of nerves at lower leg level
0.671 0.329 0.000
S81 Open wound of lower leg
0.671 0.329 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.671 0.329 0.000
I73.0 Raynaud's syndrome
0.671 0.329 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.670 0.330 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.670 0.330 0.000
L40-L45 Papulosquamous disorders
0.670 0.330 0.000
T87 Complications peculiar to reattachment and amputation
0.668 0.332 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.668 0.332 0.000
G47.3 Sleep apnoea
0.668 0.332 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.668 0.332 0.000
D47.2 Monoclonal gammopathy
0.667 0.333 0.000
C92 Myeloid leukaemia
0.667 0.333 0.000
H91.9 Hearing loss, unspecified
0.666 0.334 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.666 0.334 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.666 0.334 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.666 0.334 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.665 0.335 0.000
M34 Systemic sclerosis
0.665 0.335 0.000
M33 Dermatopolymyositis
0.665 0.335 0.000
M32 Systemic lupus erythematosus
0.665 0.335 0.000
M30 Polyarteritis nodosa and related conditions
0.665 0.335 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.665 0.335 0.000
M54.56 Low back pain (Lumbar region)
0.665 0.335 0.000
D17 Benign lipomatous neoplasm
0.665 0.335 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.665 0.335 0.000
M54.6 Pain in thoracic spine
0.665 0.335 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.665 0.335 0.000
R50 Fever of unknown origin
0.664 0.336 0.000
T18 Foreign body in alimentary tract
0.662 0.338 0.000
R63.0 Anorexia
0.661 0.339 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.661 0.339 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.660 0.340 0.000
G95 Other diseases of spinal cord
0.658 0.342 0.000
C43.4 Malignant melanoma of scalp and neck
0.657 0.343 0.000
G81.1 Spastic hemiplegia
0.657 0.343 0.000
G81.0 Flaccid hemiplegia
0.657 0.343 0.000
L85.9 Epidermal thickening, unspecified
0.656 0.344 0.000
H43-H45 Disorders of vitreous body and globe
0.656 0.344 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.655 0.344 0.000
W00-W19 Falls
0.655 0.345 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.655 0.345 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.655 0.345 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.655 0.345 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.654 0.346 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.654 0.346 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.654 0.346 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.654 0.346 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.654 0.346 0.000
Y35-Y36 Legal intervention and operations of war
0.654 0.346 0.000
Y10-Y34 Event of undetermined intent
0.654 0.346 0.000
Y00-Y09 Assault
0.654 0.346 0.000
X85-X99 Assault
0.654 0.346 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.654 0.346 0.000
X50-X57 Overexertion, travel and privation
0.654 0.346 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.346 0.000
X30-X39 Exposure to forces of nature
0.654 0.346 0.000
X20-X29 Contact with venomous animals and plants
0.654 0.346 0.000
X10-X19 Contact with heat and hot substances
0.654 0.346 0.000
X00-X09 Exposure to smoke, fire and flames
0.654 0.346 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.654 0.346 0.000
W75-W84 Other accidental threats to breathing
0.654 0.346 0.000
W65-W74 Accidental drowning and submersion
0.654 0.346 0.000
W50-W64 Exposure to animate mechanical forces
0.654 0.346 0.000
V98-V99 Other and unspecified transport accidents
0.654 0.346 0.000
V95-V97 Air and space transport accidents
0.654 0.346 0.000
V90-V94 Water transport accidents
0.654 0.346 0.000
V80-V89 Other land transport accidents
0.654 0.346 0.000
V70-V79 Bus occupant injured in transport accident
0.654 0.346 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.654 0.346 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.654 0.346 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.654 0.346 0.000
V01-V09 Pedestrian injured in transport accident
0.654 0.346 0.000
Chapter I Certain infectious and parasitic diseases
0.653 0.347 0.000
I67.1 Cerebral aneurysm, nonruptured
0.652 0.347 0.000
M31.6 Other giant cell arteritis
0.652 0.348 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G96 Other disorders of central nervous system
0.652 0.348 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.652 0.348 0.000
G90 Disorders of autonomic nervous system
0.652 0.348 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G92 Toxic encephalopathy
0.652 0.348 0.000
I77.6 Arteritis, unspecified
0.652 0.348 0.000
M40-M43 Deforming dorsopathies
0.652 0.348 0.000
R26.3 Immobility
0.651 0.348 0.000
R74 Abnormal serum enzyme levels
0.651 0.349 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.651 0.349 0.000
I95 Hypotension
0.650 0.350 0.000
I77.8 Other specified disorders of arteries and arterioles
0.650 0.350 0.000
I77.5 Necrosis of artery
0.650 0.350 0.000
I77.4 Coeliac artery compression syndrome
0.650 0.350 0.000
I77.3 Arterial fibromuscular dysplasia
0.650 0.350 0.000
I77.2 Rupture of artery
0.650 0.350 0.000
I77.0 Arteriovenous fistula, acquired
0.650 0.350 0.000
T78.4 Allergy, unspecified
0.649 0.351 0.000
R52.2 Other chronic pain
0.649 0.351 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.649 0.351 0.000
C64-C68 Malignant neoplasms of urinary tract
0.648 0.352 0.000
Z98.8 Other specified postsurgical states
0.648 0.352 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.648 0.352 0.000
I74.8 Embolism and thrombosis of other arteries
0.648 0.352 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2025 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.