TreeWAS – Variant ID: rs117352425

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I20 Angina pectoris	0.999	0.001
I30-I52 Other forms of heart disease	0.996	0.004
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.995	0.005
Chapter XXI Factors influencing health status and contact with health services	0.991	0.009
I20.9 Angina pectoris, unspecified	0.990	0.010
T36-T50 Poisoning by drugs, medicaments and biological substances	0.986	0.014
I50 Heart failure	0.984	0.016
Chapter VI Diseases of the nervous system	0.982	0.018
Z40-Z54 Persons encountering health services for specific procedures and health care	0.977	0.023
S60-S69 Injuries to the wrist and hand	0.974	0.026
I25.1 Atherosclerotic heart disease	0.973	0.027
Chapter XX External causes of morbidity and mortality	0.970	0.030
I21 Acute myocardial infarction	0.968	0.032
I25.9 Chronic ischaemic heart disease, unspecified	0.967	0.033
I50.1 Left ventricular failure	0.963	0.037
T81 Complications of procedures, not elsewhere classified	0.960	0.040
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.954	0.046
I20.0 Unstable angina	0.954	0.046
I51 Complications and ill-defined descriptions of heart disease	0.952	0.048
I70-I79 Diseases of arteries, arterioles and capillaries	0.951	0.049
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.948	0.052
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.948	0.052
Chapter VIII Diseases of the ear and mastoid process	0.947	0.053
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.937	0.063
Z45 Adjustment and management of implanted device	0.934	0.066
I25.8 Other forms of chronic ischaemic heart disease	0.933	0.067
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.932	0.068
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.931	0.069
Z42 Follow-up care involving plastic surgery	0.926	0.074
M50-M54 Other dorsopathies	0.926	0.074
G90-G99 Other disorders of the nervous system	0.919	0.081
I60-I69 Cerebrovascular diseases	0.917	0.083
I25.2 Old myocardial infarction	0.916	0.084
M54 Dorsalgia	0.914	0.086
Z91 Personal history of risk-factors, not elsewhere classified	0.911	0.089
T39.1 4-Aminophenol derivatives	0.910	0.090
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.908	0.092
Chapter I Certain infectious and parasitic diseases	0.906	0.094
Chapter VII Diseases of the eye and adnexa	0.906	0.094
H90-H95 Other disorders of ear	0.899	0.101
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.898	0.102
I21.9 Acute myocardial infarction, unspecified	0.896	0.104
I24 Other acute ischaemic heart diseases	0.896	0.104
Z50 Care involving use of rehabilitation procedures	0.895	0.105
M54.5 Low back pain	0.887	0.113
I73 Other peripheral vascular diseases	0.883	0.117
Y83.2 Surgical operation with anastomosis, bypass or graft	0.881	0.119
G50-G59 Nerve, nerve root and plexus disorders	0.879	0.121
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.878	0.122
S61 Open wound of wrist and hand	0.875	0.125
S66 Injury of muscle and tendon at wrist and hand level	0.871	0.129
Y83.1 Surgical operation with implant of artificial internal device	0.871	0.129
I21.0 Acute transmural myocardial infarction of anterior wall	0.870	0.130
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.868	0.132
I51.7 Cardiomegaly	0.865	0.135
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.865	0.135
Chapter X Diseases of the respiratory system	0.864	0.136
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.863	0.137
G40-G47 Episodic and paroxysmal disorders	0.862	0.138
I47 Paroxysmal tachycardia	0.858	0.142
Z42.1 Follow-up care involving plastic surgery of breast	0.858	0.142
Z98 Other postsurgical states	0.855	0.145
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.855	0.145
I73.9 Peripheral vascular disease, unspecified	0.852	0.148
Z45.2 Adjustment and management of vascular access device	0.851	0.149
A30-A49 Other bacterial diseases	0.850	0.150
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.849	0.151
I50.0 Congestive heart failure	0.847	0.153
I77 Other disorders of arteries and arterioles	0.845	0.155
I05-I09 Chronic rheumatic heart diseases	0.838	0.161
H90 Conductive and sensorineural hearing loss	0.837	0.163
Chapter XXII Codes for special purposes	0.837	0.163
Z97 Presence of other devices	0.834	0.166
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.832	0.168
G80-G83 Cerebral palsy and other paralytic syndromes	0.832	0.168
Z88.4 Personal history of allergy to anaesthetic agent	0.827	0.173
M54.56 Low back pain (Lumbar region)	0.827	0.173
Z22 Carrier of infectious disease	0.825	0.175
Z40 Prophylactic surgery	0.824	0.176
H25-H28 Disorders of lens	0.822	0.178
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.820	0.180
A41 Other septicaemia	0.814	0.186
T66-T78 Other and unspecified effects of external causes	0.814	0.186
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.811	0.189
S20-S29 Injuries to the thorax	0.810	0.190
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.810	0.190
I44 Atrioventricular and left bundle-branch block	0.805	0.195
T86 Failure and rejection of transplanted organs and tissues	0.805	0.195
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.801	0.199
H26 Other cataract	0.800	0.200
Z45.1 Adjustment and management of infusion pump	0.800	0.200
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.798	0.202
I67 Other cerebrovascular diseases	0.797	0.203
Z45.8 Adjustment and management of other implanted devices	0.796	0.204
M54.1 Radiculopathy	0.795	0.205
I51.9 Heart disease, unspecified	0.794	0.206
I24.8 Other forms of acute ischaemic heart disease	0.793	0.207
Z94 Transplanted organ and tissue status	0.792	0.208
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.790	0.210
H26.9 Cataract, unspecified	0.787	0.213
I51.8 Other ill-defined heart diseases	0.785	0.215
S62 Fracture at wrist and hand level	0.785	0.215
I64 Stroke, not specified as haemorrhage or infarction	0.784	0.216
G91 Hydrocephalus	0.784	0.216
T80 Complications following infusion, transfusion and therapeutic injection	0.783	0.217
Y83.6 Removal of other organ (partial) (total)	0.780	0.220
Z46 Fitting and adjustment of other devices	0.780	0.220
I22 Subsequent myocardial infarction	0.779	0.221
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.776	0.224
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.775	0.225
M45-M49 Spondylopathies	0.772	0.228
Z47 Other orthopaedic follow-up care	0.771	0.229
Z97.5 Presence of (intra-uterine) contraceptive device	0.771	0.229
Z98.0 Intestinal bypass and anastomosis status	0.770	0.230
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.770	0.230
G57 Mononeuropathies of lower limb	0.767	0.233
T81.8 Other complications of procedures, not elsewhere classified	0.767	0.233
Z22.3 Carrier of other specified bacterial diseases	0.766	0.234
I20.8 Other forms of angina pectoris	0.766	0.234
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.764	0.236
I38 Endocarditis, valve unspecified	0.763	0.237
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.763	0.237
G93 Other disorders of brain	0.763	0.237
H60-H62 Diseases of external ear	0.762	0.238
I21.4 Acute subendocardial myocardial infarction	0.761	0.239
Z49 Care involving dialysis	0.760	0.240
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.760	0.240
T39.0 Salicylates	0.758	0.242
T15-T19 Effects of foreign body entering through natural orifice	0.756	0.244
S70-S79 Injuries to the hip and thigh	0.756	0.244
G95 Other diseases of spinal cord	0.755	0.245
T79-T79 Certain early complications of trauma	0.754	0.246
M65-M68 Disorders of synovium and tendon	0.754	0.246
H55-H59 Other disorders of eye and adnexa	0.754	0.246
S60 Superficial injury of wrist and hand	0.753	0.247
I46 Cardiac arrest	0.750	0.250
S61.0 Open wound of finger(s) without damage to nail	0.747	0.253
I33 Acute and subacute endocarditis	0.746	0.254
G47 Sleep disorders	0.746	0.254
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.745	0.255
Chapter II Neoplasms	0.744	0.256
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.743	0.257
J30-J39 Other diseases of upper respiratory tract	0.740	0.260
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.740	0.260
I50.9 Heart failure, unspecified	0.740	0.260
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.740	0.260
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.736	0.264
T85 Complications of other internal prosthetic devices, implants and grafts	0.736	0.264
I47.1 Supraventricular tachycardia	0.735	0.265
Z90 Acquired absence of organs, not elsewhere classified	0.734	0.266
I74 Arterial embolism and thrombosis	0.734	0.266
Z88.1 Personal history of allergy to other antibiotic agents	0.734	0.266
Z50.2 Alcohol rehabilitation	0.730	0.269
Y83.3 Surgical operation with formation of external stoma	0.729	0.271
J95-J99 Other diseases of the respiratory system	0.728	0.272
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.727	0.273
H65-H75 Diseases of middle ear and mastoid	0.726	0.274
I69 Sequelae of cerebrovascular disease	0.725	0.275
M54.9 Dorsalgia, unspecified	0.725	0.275
Z29 Need for other prophylactic measures	0.724	0.275
T50.9 Other and unspecified drugs, medicaments and biological substances	0.722	0.278
Z50.0 Cardiac rehabilitation	0.721	0.279
I08 Multiple valve diseases	0.721	0.279
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.720	0.280
I44.7 Left bundle-branch block, unspecified	0.719	0.281
S67 Crushing injury of wrist and hand	0.719	0.281
G82 Paraplegia and tetraplegia	0.718	0.282
G51 Facial nerve disorders	0.718	0.282
M54.57 Low back pain (Lumbosacral region)	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.3 Aneurysm of heart	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
G40 Epilepsy	0.716	0.284
I20.1 Angina pectoris with documented spasm	0.716	0.284
Z86 Personal history of certain other diseases	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.714	0.286
I48 Atrial fibrillation and flutter	0.714	0.286
I43 Cardiomyopathy in diseases classified elsewhere	0.714	0.286
I41 Myocarditis in diseases classified elsewhere	0.714	0.286
I40 Acute myocarditis	0.714	0.286
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.714	0.286
I37 Pulmonary valve disorders	0.714	0.286
I36 Nonrheumatic tricuspid valve disorders	0.714	0.286
I32 Pericarditis in diseases classified elsewhere	0.714	0.286
I30 Acute pericarditis	0.714	0.286
A41.9 Septicaemia, unspecified	0.714	0.286
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.714	0.286
T88 Other complications of surgical and medical care, not elsewhere classified	0.713	0.286
T87 Complications peculiar to reattachment and amputation	0.713	0.286
S80-S89 Injuries to the knee and lower leg	0.713	0.287
I62 Other nontraumatic intracranial haemorrhage	0.713	0.287
A41.5 Septicaemia due to other Gram-negative organisms	0.713	0.287
H53-H54 Visual disturbances and blindness	0.713	0.287
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.713	0.287
Z88.6 Personal history of allergy to analgesic agent	0.711	0.288
S61.8 Open wound of other parts of wrist and hand	0.711	0.289
I24.9 Acute ischaemic heart disease, unspecified	0.711	0.289
Q00-Q07 Congenital malformations of the nervous system	0.711	0.289
M54.16 Radiculopathy (Lumbar region)	0.711	0.289
M20-M25 Other joint disorders	0.710	0.290
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.710	0.290
Z91.6 Personal history of other physical trauma	0.708	0.292
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.707	0.293
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.707	0.293
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.707	0.293
T46 Poisoning by agents primarily affecting the cardiovascular system	0.707	0.293
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.707	0.293
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.707	0.293
T41 Poisoning by anaesthetics and therapeutic gases	0.707	0.293
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.707	0.293
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.707	0.293
T36 Poisoning by systemic antibiotics	0.707	0.293
I25.5 Ischaemic cardiomyopathy	0.705	0.295
H93 Other disorders of ear, not elsewhere classified	0.705	0.295
G70-G73 Diseases of myoneural junction and muscle	0.704	0.296
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.704	0.296
G00-G09 Inflammatory diseases of the central nervous system	0.704	0.296
Z60 Problems related to social environment	0.704	0.296
Y60-Y69 Misadventures to patients during surgical and medical care	0.703	0.297
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.702	0.298
W20-W49 Exposure to inanimate mechanical forces	0.701	0.299
Q60-Q64 Congenital malformations of the urinary system	0.701	0.299
M80-M85 Disorders of bone density and structure	0.701	0.299
Z54 Convalescence	0.700	0.300
Z44 Fitting and adjustment of external prosthetic device	0.700	0.300
S68 Traumatic amputation of wrist and hand	0.700	0.300
S64 Injury of nerves at wrist and hand level	0.699	0.300
I35 Nonrheumatic aortic valve disorders	0.699	0.301
T91 Sequelae of injuries of neck and trunk	0.699	0.301
S69 Other and unspecified injuries of wrist and hand	0.698	0.302
S65 Injury of blood vessels at wrist and hand level	0.698	0.302
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.698	0.302
T90 Sequelae of injuries of head	0.698	0.302
H91 Other hearing loss	0.698	0.302
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.697	0.302
Z52 Donors of organs and tissues	0.697	0.303
M53 Other dorsopathies, not elsewhere classified	0.696	0.303
M54.3 Sciatica	0.696	0.304
Z42.0 Follow-up care involving plastic surgery of head and neck	0.696	0.304
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.696	0.304
Y35-Y36 Legal intervention and operations of war	0.696	0.304
Y10-Y34 Event of undetermined intent	0.696	0.304
Y00-Y09 Assault	0.696	0.304
X85-X99 Assault	0.696	0.304
X58-X59 Accidental exposure to other and unspecified factors	0.696	0.304
X50-X57 Overexertion, travel and privation	0.696	0.304
X40-X49 Accidental poisoning by and exposure to noxious substances	0.696	0.304
X30-X39 Exposure to forces of nature	0.696	0.304
X20-X29 Contact with venomous animals and plants	0.696	0.304
X10-X19 Contact with heat and hot substances	0.696	0.304
X00-X09 Exposure to smoke, fire and flames	0.696	0.304
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.696	0.304
W75-W84 Other accidental threats to breathing	0.696	0.304
W65-W74 Accidental drowning and submersion	0.696	0.304
W50-W64 Exposure to animate mechanical forces	0.696	0.304
V98-V99 Other and unspecified transport accidents	0.696	0.304
V95-V97 Air and space transport accidents	0.696	0.304
V90-V94 Water transport accidents	0.696	0.304
V80-V89 Other land transport accidents	0.696	0.304
V70-V79 Bus occupant injured in transport accident	0.696	0.304
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.696	0.304
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.696	0.304
V40-V49 Car occupant injured in transport accident	0.696	0.304
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.696	0.304
V20-V29 Motorcycle rider injured in transport accident	0.696	0.304
V01-V09 Pedestrian injured in transport accident	0.696	0.304
I21.X Presumed acute myicardial infaction (unconfirmed)	0.694	0.306
I21.3 Acute transmural myocardial infarction of unspecified site	0.694	0.306
I21.2 Acute transmural myocardial infarction of other sites	0.694	0.306
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.694	0.306
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.694	0.306
I10-I15 Hypertensive diseases	0.694	0.306
M91-M94 Chondropathies	0.694	0.306
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.693	0.307
X60-X84 Intentional self-harm	0.692	0.308
M54.59 Low back pain (Site unspecified)	0.691	0.309
I77.6 Arteritis, unspecified	0.691	0.309
M86-M90 Other osteopathies	0.691	0.309
M40-M43 Deforming dorsopathies	0.690	0.309
G54 Nerve root and plexus disorders	0.689	0.311
T81.9 Unspecified complication of procedure	0.688	0.311
T81.7 Vascular complications following a procedure, not elsewhere classified	0.688	0.311
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.688	0.311
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.688	0.311
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.688	0.311
H90.3 Sensorineural hearing loss, bilateral	0.689	0.311
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.688	0.312
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.687	0.313
A00-A09 Intestinal infectious diseases	0.687	0.313
Z98.2 Presence of cerebrospinal fluid drainage device	0.686	0.314
G50 Disorders of trigeminal nerve	0.685	0.315
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.684	0.316
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.684	0.316
T39.4 Antirheumatics, not elsewhere classified	0.684	0.316
T39.2 Pyrazolone derivatives	0.684	0.316
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.684	0.316
H90.2 Conductive hearing loss, unspecified	0.684	0.316
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.684	0.316
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.684	0.316
I51.6 Cardiovascular disease, unspecified	0.683	0.317
I51.5 Myocardial degeneration	0.683	0.317
I51.4 Myocarditis, unspecified	0.683	0.317
I51.3 Intracardiac thrombosis, not elsewhere classified	0.683	0.317
I51.2 Rupture of papillary muscle, not elsewhere classified	0.683	0.317
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.683	0.317
I51.0 Cardiac septal defect, acquired	0.683	0.317
W00-W19 Falls	0.682	0.318
G57.6 Lesion of plantar nerve	0.682	0.318
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.682	0.318
I72 Other aneurysm	0.682	0.318
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.680	0.320
M60-M63 Disorders of muscles	0.680	0.320
M00-M03 Infectious arthropathies	0.680	0.320
S40-S49 Injuries to the shoulder and upper arm	0.680	0.320
I67.8 Other specified cerebrovascular diseases	0.679	0.321
S90-S99 Injuries to the ankle and foot	0.678	0.321
G47.9 Sleep disorder, unspecified	0.678	0.322
J20-J22 Other acute lower respiratory infections	0.678	0.322
J09-J18 Influenza and pneumonia	0.678	0.322
T42.4 Benzodiazepines	0.677	0.323
G96 Other disorders of central nervous system	0.677	0.323
G99 Other disorders of nervous system in diseases classified elsewhere	0.677	0.323
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.676	0.324
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.674	0.326
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.674	0.326
G58 Other mononeuropathies	0.673	0.327
T84.2 Mechanical complication of internal fixation device of other bones	0.673	0.327
Z50.1 Other physical therapy	0.673	0.327
Z63 Other problems related to primary support group, including family circumstances	0.672	0.328
A41.1 Septicaemia due to other specified staphylococcus	0.672	0.328
S62.5 Fracture of thumb	0.670	0.330
Z45.9 Adjustment and management of unspecified implanted device	0.670	0.330
Z45.3 Adjustment and management of implanted hearing device	0.670	0.330
I77.8 Other specified disorders of arteries and arterioles	0.669	0.330
I70 Atherosclerosis	0.669	0.331
Y83.5 Amputation of limb(s)	0.668	0.332
Y83.0 Surgical operation with transplant of whole organ	0.668	0.332
T86.8 Failure and rejection of other transplanted organs and tissues	0.668	0.332
I60 Subarachnoid haemorrhage	0.667	0.333
Z89 Acquired absence of limb	0.667	0.333
Z84 Family history of other conditions	0.667	0.333
Z81 Family history of mental and behavioural disorders	0.667	0.333
T75 Effects of other external causes	0.666	0.334
H92 Otalgia and effusion of ear	0.666	0.334
H90.5 Sensorineural hearing loss, unspecified	0.666	0.334
B95-B98 Bacterial, viral and other infectious agents	0.665	0.335
Z42.9 Follow-up care involving plastic surgery, unspecified	0.664	0.336
Z42.8 Follow-up care involving plastic surgery of other body part	0.664	0.336
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.664	0.336
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.664	0.336
I47.2 Ventricular tachycardia	0.662	0.338
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.659	0.341
G94 Other disorders of brain in diseases classified elsewhere	0.659	0.341
G90 Disorders of autonomic nervous system	0.659	0.341
G98 Other disorders of nervous system, not elsewhere classified	0.659	0.341
G92 Toxic encephalopathy	0.659	0.341
I45 Other conduction disorders	0.659	0.341
S00-S09 Injuries to the head	0.658	0.342
I68 Cerebrovascular disorders in diseases classified elsewhere	0.658	0.342
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.658	0.342
Z50.5 Speech therapy	0.656	0.344
J00-J06 Acute upper respiratory infections	0.656	0.344
M54.8 Other dorsalgia	0.655	0.345
M54.6 Pain in thoracic spine	0.655	0.345
M54.4 Lumbago with sciatica	0.655	0.345
M54.0 Panniculitis affecting regions of neck and back	0.655	0.345
C50-C50 Malignant neoplasm of breast	0.655	0.345
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.654	0.346
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.653	0.347
Z91.7 Personal history of female genital mutilation	0.653	0.347
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.653	0.347
Z91.3 Personal history of unhealthy sleep-wake schedule	0.653	0.347
Z91.2 Personal history of poor personal hygiene	0.653	0.347
H10-H13 Disorders of conjunctiva	0.652	0.348
Z28 Immunisation not carried out	0.651	0.349
Z27 Need for immunisation against combinations of infectious diseases	0.651	0.349
Z26 Need for immunisation against other single infectious diseases	0.651	0.349
Z25 Need for immunisation against other single viral diseases	0.651	0.349
Z24 Need for immunisation against certain single viral diseases	0.651	0.349
Z23 Need for immunisation against single bacterial diseases	0.651	0.349
Z20 Contact with and exposure to communicable diseases	0.651	0.349
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.651	0.349
S61.9 Open wound of wrist and hand, part unspecified	0.651	0.349
D80-D89 Certain disorders involving the immune mechanism	0.651	0.349
I77.1 Stricture of artery	0.651	0.349
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.651	0.349
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.650	0.350
B99-B99 Other infectious diseases	0.650	0.350
B90-B94 Sequelae of infectious and parasitic diseases	0.650	0.350
B85-B89 Pediculosis, acariasis and other infestations	0.650	0.350
B65-B83 Helminthiases	0.650	0.350
B50-B64 Protozoal diseases	0.650	0.350
B20-B24 Human immunodeficiency virus [HIV] disease	0.650	0.350
B15-B19 Viral hepatitis	0.650	0.350
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.650	0.350
A80-A89 Viral infections of the central nervous system	0.650	0.350
A75-A79 Rickettsioses	0.650	0.350
A70-A74 Other diseases caused by chlamydiae	0.650	0.350
A65-A69 Other spirochaetal diseases	0.650	0.350
A50-A64 Infections with a predominantly sexual mode of transmission	0.650	0.350
A20-A28 Certain zoonotic bacterial diseases	0.650	0.350
A15-A19 Tuberculosis	0.650	0.350
H46-H48 Disorders of optic nerve and visual pathways	0.649	0.351
H43-H45 Disorders of vitreous body and globe	0.649	0.351
D37-D48 Neoplasms of uncertain or unknown behaviour	0.649	0.351
G59 Mononeuropathy in diseases classified elsewhere	0.648	0.352
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.648	0.352
T59 Toxic effect of other gases, fumes and vapours	0.647	0.353
I77.9 Disorder of arteries and arterioles, unspecified	0.647	0.353
I21.1 Acute transmural myocardial infarction of inferior wall	0.647	0.353
J80-J84 Other respiratory diseases principally affecting the interstitium	0.646	0.354
Z86.5 Personal history of other mental and behavioural disorders	0.646	0.354
J60-J70 Lung diseases due to external agents	0.645	0.354
S61.1 Open wound of finger(s) with damage to nail	0.645	0.355
I44.0 Atrioventricular block, first degree	0.645	0.355
Q50-Q56 Congenital malformations of genital organs	0.645	0.355
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.645	0.355
H94 Other disorders of ear in diseases classified elsewhere	0.645	0.355
Z88.7 Personal history of allergy to serum and vaccine	0.644	0.356
V10-V19 Pedal cyclist injured in transport accident	0.643	0.357
T92 Sequelae of injuries of upper limb	0.643	0.357
S22 Fracture of rib(s), sternum and thoracic spine	0.643	0.357
T83.0 Mechanical complication of urinary (indwelling) catheter	0.642	0.358
Z94.0 Kidney transplant status	0.642	0.358
I24.1 Dressler's syndrome	0.642	0.358
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.642	0.358
G91.9 Hydrocephalus, unspecified	0.642	0.358
Z50.6 Orthoptic training	0.641	0.359
Z50.4 Psychotherapy, not elsewhere classified	0.641	0.359
Z50.3 Drug rehabilitation	0.641	0.359
M70-M79 Other soft tissue disorders	0.641	0.359
C51-C58 Malignant neoplasms of female genital organs	0.639	0.361
Z46.6 Fitting and adjustment of urinary device	0.638	0.362
Z91.5 Personal history of self-harm	0.638	0.362
M48 Other spondylopathies	0.637	0.363
M54.55 Low back pain (Thoracolumbar region)	0.636	0.364
M54.54 Low back pain-Thoracic	0.636	0.364
M54.53 Low back pain-Cervicothoracic	0.636	0.364
M54.52 Low back pain-Cervical	0.636	0.364
M54.51 Low back pain-Occipit-atl-axl	0.636	0.364
M54.50 Low back pain (Multiple sites in spine)	0.636	0.364
Y83.4 Other reconstructive surgery	0.636	0.364
U80 Agent resistant to penicillin and related antibiotics	0.636	0.364
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.636	0.364
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.636	0.364
D00-D09 In situ neoplasms	0.635	0.365
Z98.8 Other specified postsurgical states	0.634	0.366
I73.8 Other specified peripheral vascular diseases	0.633	0.367
I73.1 Thromboangiitis obliterans [Buerger]	0.633	0.367
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.633	0.367
I69.3 Sequelae of cerebral infarction	0.632	0.368
I27 Other pulmonary heart diseases	0.632	0.368
I71 Aortic aneurysm and dissection	0.632	0.368
G91.1 Obstructive hydrocephalus	0.632	0.368
T81.3 Disruption of operation wound, not elsewhere classified	0.631	0.369
Y83.9 Surgical procedure, unspecified	0.631	0.369
G53 Cranial nerve disorders in diseases classified elsewhere	0.631	0.369
G52 Disorders of other cranial nerves	0.631	0.369
G93.2 Benign intracranial hypertension	0.630	0.370
T80.2 Infections following infusion, transfusion and therapeutic injection	0.630	0.370
Z94.7 Corneal transplant status	0.630	0.370
G43 Migraine	0.630	0.370
J95 Postprocedural respiratory disorders, not elsewhere classified	0.629	0.371
H57 Other disorders of eye and adnexa	0.629	0.371
S20 Superficial injury of thorax	0.629	0.371
T84.1 Mechanical complication of internal fixation device of bones of limb	0.628	0.372
G95.8 Other specified diseases of spinal cord	0.628	0.372
S61.7 Multiple open wounds of wrist and hand	0.627	0.373
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.627	0.373
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.625	0.375
S66.8 Injury of other muscles and tendons at wrist and hand level	0.625	0.375
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.625	0.375
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.625	0.375
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.625	0.375
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.625	0.375
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.625	0.375
I42 Cardiomyopathy	0.625	0.375
J30 Vasomotor and allergic rhinitis	0.624	0.376
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.624	0.376
T93 Sequelae of injuries of lower limb	0.624	0.376
H40-H42 Glaucoma	0.624	0.376
H60 Otitis externa	0.623	0.377
M45 Ankylosing spondylitis	0.622	0.378
T51 Toxic effect of alcohol	0.622	0.378
I67.1 Cerebral aneurysm, nonruptured	0.621	0.379
Z57 Occupational exposure to risk-factors	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations