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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117470014
log Bayes Factor = 18.6761
Chromosome 12   position 74,652,195  (GRCh37) Explore rs117470014 on Ensembl!
Variant rs117470014 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
J95-J99 Other diseases of the respiratory system
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
J32 Chronic sinusitis
0.986 0.014 0.000
J98 Other respiratory disorders
0.985 0.015 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.978 0.022 0.000
I51 Complications and ill-defined descriptions of heart disease
0.974 0.026 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.973 0.027 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
M15-M19 Arthrosis
0.967 0.033 0.000
M17 Gonarthrosis [arthrosis of knee]
0.963 0.037 0.000
J98.1 Pulmonary collapse
0.963 0.037 0.000
M17.1 Other primary gonarthrosis
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.962 0.038 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.962 0.038 0.000
I45 Other conduction disorders
0.960 0.040 0.000
I42 Cardiomyopathy
0.955 0.045 0.000
J33 Nasal polyp
0.954 0.046 0.000
Chapter XI Diseases of the digestive system
0.953 0.047 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.948 0.052 0.000
J90-J94 Other diseases of pleura
0.943 0.057 0.000
K70-K77 Diseases of liver
0.941 0.059 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.940 0.060 0.000
K50-K52 Noninfective enteritis and colitis
0.929 0.071 0.000
J09-J18 Influenza and pneumonia
0.928 0.072 0.000
I51.9 Heart disease, unspecified
0.924 0.076 0.000
J32.0 Chronic maxillary sinusitis
0.923 0.077 0.000
D50-D53 Nutritional anaemias
0.922 0.078 0.000
G90-G99 Other disorders of the nervous system
0.922 0.078 0.000
J30 Vasomotor and allergic rhinitis
0.920 0.080 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.919 0.081 0.000
J33.8 Other polyp of sinus
0.918 0.082 0.000
Y52 Agents primarily affecting the cardiovascular system
0.909 0.091 0.000
J81 Pulmonary oedema
0.909 0.091 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.906 0.094 0.000
D80-D89 Certain disorders involving the immune mechanism
0.905 0.095 0.000
Chapter XXII Codes for special purposes
0.904 0.096 0.000
I45.1 Other and unspecified right bundle-branch block
0.904 0.096 0.000
I49 Other cardiac arrhythmias
0.902 0.098 0.000
J98.4 Other disorders of lung
0.901 0.099 0.000
I60-I69 Cerebrovascular diseases
0.898 0.102 0.000
K76 Other diseases of liver
0.894 0.106 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.893 0.107 0.000
J32.9 Chronic sinusitis, unspecified
0.893 0.107 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.891 0.109 0.000
I73 Other peripheral vascular diseases
0.890 0.110 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.886 0.114 0.000
K50 Crohn's disease [regional enteritis]
0.885 0.115 0.000
I34 Nonrheumatic mitral valve disorders
0.884 0.116 0.000
Chapter VII Diseases of the eye and adnexa
0.880 0.120 0.000
X60-X84 Intentional self-harm
0.877 0.123 0.000
K72 Hepatic failure, not elsewhere classified
0.874 0.126 0.000
D50 Iron deficiency anaemia
0.873 0.127 0.000
J93 Pneumothorax
0.873 0.127 0.000
D69 Purpura and other haemorrhagic conditions
0.872 0.128 0.000
S80-S89 Injuries to the knee and lower leg
0.872 0.128 0.000
M45-M49 Spondylopathies
0.870 0.130 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.868 0.132 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.867 0.133 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.864 0.136 0.000
I73.9 Peripheral vascular disease, unspecified
0.863 0.137 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.862 0.138 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.860 0.140 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.858 0.142 0.000
I78 Diseases of capillaries
0.858 0.142 0.000
T42.4 Benzodiazepines
0.857 0.143 0.000
H30-H36 Disorders of choroid and retina
0.853 0.147 0.000
J90 Pleural effusion, not elsewhere classified
0.847 0.153 0.000
J30.1 Allergic rhinitis due to pollen
0.846 0.154 0.000
J18 Pneumonia, organism unspecified
0.844 0.156 0.000
I42.0 Dilated cardiomyopathy
0.840 0.160 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.839 0.161 0.000
G93 Other disorders of brain
0.838 0.162 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.837 0.163 0.000
I46 Cardiac arrest
0.837 0.163 0.000
I49.8 Other specified cardiac arrhythmias
0.837 0.163 0.000
K51 Ulcerative colitis
0.836 0.164 0.000
J93.9 Pneumothorax, unspecified
0.836 0.164 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.835 0.165 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.834 0.166 0.000
T81 Complications of procedures, not elsewhere classified
0.834 0.166 0.000
I67 Other cerebrovascular diseases
0.832 0.168 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.831 0.169 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.830 0.170 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.829 0.171 0.000
F60-F69 Disorders of adult personality and behaviour
0.829 0.171 0.000
T66-T78 Other and unspecified effects of external causes
0.829 0.171 0.000
J84 Other interstitial pulmonary diseases
0.829 0.171 0.000
J18.9 Pneumonia, unspecified
0.826 0.174 0.000
J60-J70 Lung diseases due to external agents
0.825 0.175 0.000
I42.2 Other hypertrophic cardiomyopathy
0.824 0.176 0.000
I51.7 Cardiomegaly
0.824 0.176 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.824 0.176 0.000
J32.2 Chronic ethmoidal sinusitis
0.823 0.177 0.000
Y45.0 Opioids and related analgesics
0.822 0.178 0.000
Chapter II Neoplasms
0.822 0.178 0.000
W00-W19 Falls
0.821 0.179 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.821 0.179 0.000
S70-S79 Injuries to the hip and thigh
0.821 0.179 0.000
F43 Reaction to severe stress, and adjustment disorders
0.820 0.180 0.000
S20-S29 Injuries to the thorax
0.818 0.181 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.818 0.182 0.000
D86 Sarcoidosis
0.818 0.182 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.818 0.182 0.000
H35 Other retinal disorders
0.817 0.183 0.000
I44 Atrioventricular and left bundle-branch block
0.815 0.185 0.000
D69.6 Thrombocytopenia, unspecified
0.815 0.185 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.814 0.186 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.812 0.188 0.000
F10.2 Dependence syndrome
0.805 0.195 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.804 0.196 0.000
S10-S19 Injuries to the neck
0.804 0.196 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.803 0.197 0.000
I05-I09 Chronic rheumatic heart diseases
0.801 0.199 0.000
Chapter VIII Diseases of the ear and mastoid process
0.800 0.200 0.000
K12 Stomatitis and related lesions
0.798 0.202 0.000
I86 Varicose veins of other sites
0.797 0.203 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.796 0.204 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.796 0.204 0.000
I67.9 Cerebrovascular disease, unspecified
0.796 0.204 0.000
M05-M14 Inflammatory polyarthropathies
0.795 0.205 0.000
M17.0 Primary gonarthrosis, bilateral
0.794 0.206 0.000
J10 Influenza due to identified influenza virus
0.793 0.207 0.000
K72.9 Hepatic failure, unspecified
0.792 0.208 0.000
M40-M43 Deforming dorsopathies
0.790 0.210 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.790 0.210 0.000
J32.8 Other chronic sinusitis
0.788 0.212 0.000
K50.1 Crohn's disease of large intestine
0.788 0.212 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.786 0.214 0.000
J98.6 Disorders of diaphragm
0.785 0.215 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.785 0.215 0.000
I33 Acute and subacute endocarditis
0.785 0.215 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.785 0.215 0.000
S90-S99 Injuries to the ankle and foot
0.784 0.216 0.000
I72 Other aneurysm
0.782 0.218 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
M70-M79 Other soft tissue disorders
0.782 0.218 0.000
T87 Complications peculiar to reattachment and amputation
0.779 0.220 0.000
V40-V49 Car occupant injured in transport accident
0.778 0.222 0.000
J33.9 Nasal polyp, unspecified
0.777 0.223 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.776 0.224 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.776 0.224 0.000
Chapter I Certain infectious and parasitic diseases
0.774 0.226 0.000
V10-V19 Pedal cyclist injured in transport accident
0.774 0.226 0.000
G96 Other disorders of central nervous system
0.774 0.226 0.000
S80 Superficial injury of lower leg
0.773 0.227 0.000
I34.1 Mitral (valve) prolapse
0.771 0.229 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.770 0.230 0.000
F10.4 Withdrawal state with delirium
0.768 0.232 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.768 0.232 0.000
S40-S49 Injuries to the shoulder and upper arm
0.767 0.233 0.000
I47 Paroxysmal tachycardia
0.767 0.233 0.000
K13 Other diseases of lip and oral mucosa
0.767 0.233 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.766 0.234 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.766 0.234 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.764 0.236 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.761 0.239 0.000
I45.9 Conduction disorder, unspecified
0.761 0.239 0.000
I45.3 Trifascicular block
0.761 0.239 0.000
G91 Hydrocephalus
0.760 0.240 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.758 0.242 0.000
Y40 Systemic antibiotics
0.758 0.242 0.000
T40.2 Other opioids
0.757 0.243 0.000
I74 Arterial embolism and thrombosis
0.756 0.244 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.756 0.244 0.000
K76.6 Portal hypertension
0.756 0.244 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
I71 Aortic aneurysm and dissection
0.755 0.245 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.755 0.245 0.000
G93.9 Disorder of brain, unspecified
0.754 0.246 0.000
K50.9 Crohn's disease, unspecified
0.753 0.247 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.752 0.247 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.750 0.250 0.000
L40-L45 Papulosquamous disorders
0.750 0.250 0.000
I31 Other diseases of pericardium
0.750 0.250 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.749 0.251 0.000
H35.4 Peripheral retinal degeneration
0.749 0.251 0.000
H18 Other disorders of cornea
0.749 0.251 0.000
I42.6 Alcoholic cardiomyopathy
0.749 0.251 0.000
D86.9 Sarcoidosis, unspecified
0.749 0.251 0.000
I51.8 Other ill-defined heart diseases
0.748 0.252 0.000
J37 Chronic laryngitis and laryngotracheitis
0.747 0.253 0.000
U80 Agent resistant to penicillin and related antibiotics
0.747 0.253 0.000
M47 Spondylosis
0.746 0.254 0.000
K75 Other inflammatory liver diseases
0.746 0.254 0.000
I38 Endocarditis, valve unspecified
0.746 0.254 0.000
T79-T79 Certain early complications of trauma
0.745 0.254 0.000
F10.3 Withdrawal state
0.745 0.255 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.745 0.255 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.744 0.256 0.000
T86 Failure and rejection of transplanted organs and tissues
0.743 0.257 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.742 0.258 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.742 0.258 0.000
I51.4 Myocarditis, unspecified
0.742 0.258 0.000
T92 Sequelae of injuries of upper limb
0.742 0.258 0.000
K12.1 Other forms of stomatitis
0.741 0.259 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.741 0.259 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.741 0.259 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.740 0.260 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.739 0.261 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.739 0.261 0.000
K05 Gingivitis and periodontal diseases
0.739 0.261 0.000
R40 Somnolence, stupor and coma
0.739 0.261 0.000
M17.3 Other posttraumatic gonarthrosis
0.738 0.262 0.000
I81 Portal vein thrombosis
0.738 0.262 0.000
I44.7 Left bundle-branch block, unspecified
0.738 0.262 0.000
I36 Nonrheumatic tricuspid valve disorders
0.734 0.266 0.000
G30-G32 Other degenerative diseases of the nervous system
0.734 0.266 0.000
I49.0 Ventricular fibrillation and flutter
0.733 0.267 0.000
J98.9 Respiratory disorder, unspecified
0.732 0.268 0.000
L20-L30 Dermatitis and eczema
0.732 0.268 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.730 0.269 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.731 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.729 0.271 0.000
I78.1 Naevus, nonneoplastic
0.729 0.271 0.000
M86-M90 Other osteopathies
0.729 0.271 0.000
I46.9 Cardiac arrest, unspecified
0.728 0.272 0.000
D60-D64 Aplastic and other anaemias
0.728 0.272 0.000
K72.0 Acute and subacute hepatic failure
0.727 0.273 0.000
J31.0 Chronic rhinitis
0.725 0.275 0.000
J30.4 Allergic rhinitis, unspecified
0.724 0.276 0.000
I65.2 Occlusion and stenosis of carotid artery
0.723 0.277 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.723 0.277 0.000
M60-M63 Disorders of muscles
0.723 0.277 0.000
R45 Symptoms and signs involving emotional state
0.723 0.277 0.000
K51.9 Ulcerative colitis, unspecified
0.722 0.278 0.000
F41 Other anxiety disorders
0.722 0.278 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.722 0.278 0.000
X20-X29 Contact with venomous animals and plants
0.720 0.279 0.000
F30-F39 Mood [affective] disorders
0.720 0.280 0.000
F11 Mental and behavioural disorders due to use of opioids
0.720 0.280 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.719 0.281 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.718 0.282 0.000
K50.8 Other Crohn's disease
0.718 0.282 0.000
K10 Other diseases of jaws
0.718 0.282 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H36 Retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.716 0.284 0.000
H35.8 Other specified retinal disorders
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
S00-S09 Injuries to the head
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
I82 Other venous embolism and thrombosis
0.714 0.286 0.000
K73 Chronic hepatitis, not elsewhere classified
0.714 0.286 0.000
F99-F99 Unspecified mental disorder
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
F60 Specific personality disorders
0.712 0.288 0.000
D55-D59 Haemolytic anaemias
0.711 0.289 0.000
G93.8 Other specified disorders of brain
0.710 0.290 0.000
J96 Respiratory failure, not elsewhere classified
0.710 0.290 0.000
I26 Pulmonary embolism
0.710 0.290 0.000
D50.9 Iron deficiency anaemia, unspecified
0.710 0.290 0.000
F43.2 Adjustment disorders
0.708 0.292 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.707 0.293 0.000
J32.4 Chronic pansinusitis
0.707 0.293 0.000
J32.3 Chronic sphenoidal sinusitis
0.707 0.293 0.000
J32.1 Chronic frontal sinusitis
0.707 0.293 0.000
K76.7 Hepatorenal syndrome
0.707 0.293 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.707 0.293 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.706 0.294 0.000
J98.3 Compensatory emphysema
0.706 0.294 0.000
J98.2 Interstitial emphysema
0.706 0.294 0.000
T78 Adverse effects, not elsewhere classified
0.705 0.295 0.000
I45.6 Preexcitation syndrome
0.705 0.295 0.000
I49.3 Ventricular premature depolarisation
0.705 0.295 0.000
R46 Symptoms and signs involving appearance and behaviour
0.704 0.295 0.000
K76.8 Other specified diseases of liver
0.704 0.296 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.703 0.297 0.000
K65-K67 Diseases of peritoneum
0.703 0.297 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.702 0.298 0.000
I63 Cerebral infarction
0.701 0.299 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
Y44 Agents primarily affecting blood constituents
0.701 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.700 0.300 0.000
D48.1 Connective and other soft tissue
0.700 0.300 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.700 0.300 0.000
S79 Other and unspecified injuries of hip and thigh
0.699 0.300 0.000
M47.8 Other spondylosis
0.699 0.301 0.000
M00-M03 Infectious arthropathies
0.698 0.302 0.000
I51.6 Cardiovascular disease, unspecified
0.698 0.302 0.000
I51.5 Myocardial degeneration
0.698 0.302 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.698 0.302 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.698 0.302 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.698 0.302 0.000
I51.0 Cardiac septal defect, acquired
0.698 0.302 0.000
G70-G73 Diseases of myoneural junction and muscle
0.697 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.697 0.303 0.000
M06 Other rheumatoid arthritis
0.697 0.303 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.696 0.304 0.000
F45 Somatoform disorders
0.695 0.305 0.000
I85 Oesophageal varices
0.694 0.306 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.694 0.306 0.000
I80 Phlebitis and thrombophlebitis
0.694 0.306 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.694 0.306 0.000
X62.9 Unspecified place
0.694 0.306 0.000
M15 Polyarthrosis
0.693 0.307 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.693 0.307 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.692 0.308 0.000
D52 Folate deficiency anaemia
0.692 0.308 0.000
G20-G26 Extrapyramidal and movement disorders
0.692 0.308 0.000
F43.1 Posttraumatic stress disorder
0.692 0.308 0.000
D45 Polycythaemia vera
0.691 0.309 0.000
B95-B98 Bacterial, viral and other infectious agents
0.691 0.309 0.000
M17.5 Other secondary gonarthrosis
0.691 0.309 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.691 0.309 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.691 0.309 0.000
R47-R49 Symptoms and signs involving speech and voice
0.691 0.309 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.690 0.310 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.690 0.310 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.310 0.000
S80.9 Superficial injury of lower leg, unspecified
0.690 0.310 0.000
I08 Multiple valve diseases
0.690 0.310 0.000
Y95 Nosocomial condition
0.690 0.310 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.689 0.310 0.000
I45.8 Other specified conduction disorders
0.688 0.311 0.000
I45.5 Other specified heart block
0.688 0.311 0.000
I45.4 Nonspecific intraventricular block
0.688 0.311 0.000
I45.2 Bifascicular block
0.688 0.311 0.000
I45.0 Right fascicular block
0.688 0.311 0.000
J35 Chronic diseases of tonsils and adenoids
0.687 0.313 0.000
S82 Fracture of lower leg, including ankle
0.687 0.313 0.000
K74 Fibrosis and cirrhosis of liver
0.686 0.314 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.685 0.315 0.000
R40.2 Coma, unspecified
0.685 0.315 0.000
I42.8 Other cardiomyopathies
0.685 0.315 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.685 0.315 0.000
I42.5 Other restrictive cardiomyopathy
0.685 0.315 0.000
I42.4 Endocardial fibroelastosis
0.685 0.315 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.685 0.315 0.000
J33.1 Polypoid sinus degeneration
0.684 0.316 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.683 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.681 0.319 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.680 0.320 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.680 0.320 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.680 0.320 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.680 0.320 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.680 0.320 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.680 0.320 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.680 0.320 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.680 0.320 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.680 0.320 0.000
Q60-Q64 Congenital malformations of the urinary system
0.680 0.320 0.000
K51.2 Ulcerative (chronic) proctitis
0.680 0.320 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.679 0.321 0.000
T40.4 Other synthetic narcotics
0.678 0.322 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.678 0.322 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.677 0.323 0.000
U80.0 Penicillin resistant agent
0.677 0.323 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.324 0.000
K77 Liver disorders in diseases classified elsewhere
0.674 0.325 0.000
K71 Toxic liver disease
0.674 0.325 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.674 0.326 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.674 0.326 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.674 0.326 0.000
T42.3 Barbiturates
0.674 0.326 0.000
T42.2 Succinimides and oxazolidinediones
0.674 0.326 0.000
T42.1 Iminostilbenes
0.674 0.326 0.000
T42.0 Hydantoin derivatives
0.674 0.326 0.000
J69 Pneumonitis due to solids and liquids
0.674 0.326 0.000
F80-F89 Disorders of psychological development
0.674 0.326 0.000
M77 Other enthesopathies
0.673 0.327 0.000
I70 Atherosclerosis
0.672 0.328 0.000
J80 Adult respiratory distress syndrome
0.670 0.329 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.670 0.330 0.000
I42.9 Cardiomyopathy, unspecified
0.669 0.331 0.000
S89 Other and unspecified injuries of lower leg
0.669 0.331 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.669 0.331 0.000
I30 Acute pericarditis
0.669 0.331 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.669 0.331 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.668 0.332 0.000
G96.0 Cerebrospinal fluid leak
0.668 0.332 0.000
Y49.5 Other antipsychotics and neuroleptics
0.665 0.334 0.000
J17 Pneumonia in diseases classified elsewhere
0.665 0.335 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.665 0.335 0.000
J12 Viral pneumonia, not elsewhere classified
0.665 0.335 0.000
J14 Pneumonia due to Haemophilus influenzae
0.665 0.335 0.000
J09 Influenza due to certain identified influenza virus
0.665 0.335 0.000
J98.8 Other specified respiratory disorders
0.664 0.336 0.000
I87 Other disorders of veins
0.664 0.336 0.000
S12 Fracture of neck
0.663 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.337 0.000
H60-H62 Diseases of external ear
0.663 0.337 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.663 0.337 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.662 0.338 0.000
D50.8 Other iron deficiency anaemias
0.662 0.338 0.000
D53 Other nutritional anaemias
0.661 0.339 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.661 0.339 0.000
G90 Disorders of autonomic nervous system
0.661 0.339 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.661 0.339 0.000
G92 Toxic encephalopathy
0.661 0.339 0.000
I35 Nonrheumatic aortic valve disorders
0.661 0.339 0.000
J30.3 Other allergic rhinitis
0.660 0.340 0.000
J30.2 Other seasonal allergic rhinitis
0.660 0.340 0.000
J30.0 Vasomotor rhinitis
0.660 0.340 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.660 0.340 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.660 0.340 0.000
I86.8 Varicose veins of other specified sites
0.659 0.341 0.000
I62 Other nontraumatic intracranial haemorrhage
0.659 0.341 0.000
D67 Hereditary factor IX deficiency
0.659 0.341 0.000
D66 Hereditary factor VIII deficiency
0.659 0.341 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.659 0.341 0.000
K55-K64 Other diseases of intestines
0.658 0.342 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.658 0.342 0.000
K12.3 Oral mucositis (ulcerative)
0.657 0.343 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.657 0.343 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.657 0.343 0.000
J92 Pleural plaque
0.655 0.345 0.000
W11 Fall on and from ladder
0.655 0.345 0.000
F20 Schizophrenia
0.655 0.345 0.000
M48 Other spondylopathies
0.655 0.345 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.655 0.345 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.654 0.346 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.652 0.348 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.652 0.348 0.000
Y52.7 Peripheral vasodilators
0.652 0.348 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.652 0.348 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.652 0.348 0.000
Y52.1 Calcium-channel blockers
0.652 0.348 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.652 0.348 0.000
F17.2 Dependence syndrome
0.651 0.348 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.651 0.349 0.000
S50-S59 Injuries to the elbow and forearm
0.651 0.349 0.000
H35.7 Separation of retinal layers
0.651 0.349 0.000
M43 Other deforming dorsopathies
0.650 0.350 0.000
F48 Other neurotic disorders
0.650 0.350 0.000
F44 Dissociative [conversion] disorders
0.650 0.350 0.000
F42 Obsessive-compulsive disorder
0.650 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.649 0.350 0.000
L40 Psoriasis
0.649 0.351 0.000
D84 Other immunodeficiencies
0.649 0.351 0.000
D83 Common variable immunodeficiency
0.649 0.351 0.000
D82 Immunodeficiency associated with other major defects
0.649 0.351 0.000
D81 Combined immunodeficiencies
0.649 0.351 0.000
D80 Immunodeficiency with predominantly antibody defects
0.649 0.351 0.000
K50.0 Crohn's disease of small intestine
0.648 0.352 0.000
C79 Secondary malignant neoplasm of other sites
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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