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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117473873
log Bayes Factor = 9.65269
Chromosome 15   position 53,024,679  (GRCh37) Explore rs117473873 on Ensembl!
Variant rs117473873 is part of Cluster X0147

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
O60-O75 Complications of labour and delivery
0.995 0.005 0.000
B95-B98 Bacterial, viral and other infectious agents
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.991 0.009 0.000
Y95 Nosocomial condition
0.989 0.011 0.000
O63 Long labour
0.989 0.011 0.000
O63.1 Prolonged second stage (of labour)
0.986 0.014 0.000
E10 Insulin-dependent diabetes mellitus
0.984 0.016 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
E11 Non-insulin-dependent diabetes mellitus
0.979 0.021 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.977 0.023 0.000
F30-F39 Mood [affective] disorders
0.974 0.026 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
F31 Bipolar affective disorder
0.968 0.032 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.968 0.032 0.000
Chapter II Neoplasms
0.968 0.032 0.000
E16 Other disorders of pancreatic internal secretion
0.960 0.040 0.000
E16.2 Hypoglycaemia, unspecified
0.948 0.052 0.000
S00-S09 Injuries to the head
0.944 0.056 0.000
E10.3 With ophthalmic complications
0.941 0.059 0.000
O70 Perineal laceration during delivery
0.940 0.060 0.000
S50-S59 Injuries to the elbow and forearm
0.936 0.064 0.000
O70.1 Second degree perineal laceration during delivery
0.930 0.070 0.000
S80-S89 Injuries to the knee and lower leg
0.927 0.073 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.917 0.083 0.000
Chapter X Diseases of the respiratory system
0.917 0.083 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.910 0.090 0.000
S20-S29 Injuries to the thorax
0.909 0.091 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.907 0.093 0.000
C51-C58 Malignant neoplasms of female genital organs
0.907 0.093 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.903 0.097 0.000
Chapter XXII Codes for special purposes
0.900 0.100 0.000
J95-J99 Other diseases of the respiratory system
0.900 0.100 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.896 0.104 0.000
E70-E90 Metabolic disorders
0.893 0.107 0.000
E11.2 With renal complications
0.892 0.108 0.000
J98 Other respiratory disorders
0.891 0.109 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.890 0.110 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.885 0.115 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.884 0.116 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.884 0.116 0.000
E11.0 With coma
0.882 0.118 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.882 0.118 0.000
B15-B19 Viral hepatitis
0.880 0.120 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.878 0.122 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.878 0.122 0.000
B35-B49 Mycoses
0.878 0.122 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.875 0.125 0.000
S02 Fracture of skull and facial bones
0.875 0.125 0.000
F30 Manic episode
0.872 0.128 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.870 0.130 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.869 0.131 0.000
S06 Intracranial injury
0.868 0.132 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.866 0.134 0.000
D00-D09 In situ neoplasms
0.864 0.136 0.000
C71 Malignant neoplasm of brain
0.862 0.137 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.861 0.139 0.000
O85-O92 Complications predominantly related to the puerperium
0.853 0.147 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.852 0.148 0.000
F99-F99 Unspecified mental disorder
0.849 0.151 0.000
E10.1 With ketoacidosis
0.846 0.154 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.846 0.154 0.000
S81 Open wound of lower leg
0.844 0.156 0.000
J98.4 Other disorders of lung
0.844 0.156 0.000
T79-T79 Certain early complications of trauma
0.841 0.159 0.000
F31.7 Bipolar affective disorder, currently in remission
0.841 0.159 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.837 0.163 0.000
E11.5 With peripheral circulatory complications
0.834 0.166 0.000
E87.7 Fluid overload
0.833 0.167 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.832 0.168 0.000
C56 Malignant neoplasm of ovary
0.831 0.169 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.829 0.171 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.175 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.822 0.178 0.000
E10.8 With unspecified complications
0.821 0.179 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.821 0.179 0.000
E11.4 With neurological complications
0.818 0.182 0.000
F31.9 Bipolar affective disorder, unspecified
0.817 0.183 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.815 0.185 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.813 0.187 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.811 0.189 0.000
E40-E46 Malnutrition
0.808 0.192 0.000
M50-M54 Other dorsopathies
0.805 0.195 0.000
S05 Injury of eye and orbit
0.803 0.197 0.000
M45-M49 Spondylopathies
0.800 0.200 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.799 0.201 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.797 0.203 0.000
M40-M43 Deforming dorsopathies
0.796 0.204 0.000
O42 Premature rupture of membranes
0.792 0.208 0.000
X20-X29 Contact with venomous animals and plants
0.792 0.208 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.792 0.208 0.000
A15-A19 Tuberculosis
0.791 0.209 0.000
S56 Injury of muscle and tendon at forearm level
0.791 0.209 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.789 0.211 0.000
C91 Lymphoid leukaemia
0.789 0.211 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.788 0.212 0.000
S51 Open wound of forearm
0.788 0.212 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.785 0.215 0.000
V10-V19 Pedal cyclist injured in transport accident
0.782 0.218 0.000
J98.1 Pulmonary collapse
0.780 0.220 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.780 0.220 0.000
E11.6 With other specified complications
0.780 0.220 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.779 0.221 0.000
S89 Other and unspecified injuries of lower leg
0.777 0.223 0.000
T63 Toxic effect of contact with venomous animals
0.776 0.224 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.776 0.224 0.000
E10.2 With renal complications
0.774 0.226 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.774 0.226 0.000
B02 Zoster [herpes zoster]
0.774 0.226 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.773 0.226 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.773 0.227 0.000
V01-V09 Pedestrian injured in transport accident
0.773 0.227 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.772 0.228 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.772 0.228 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.770 0.230 0.000
T86 Failure and rejection of transplanted organs and tissues
0.769 0.231 0.000
T92 Sequelae of injuries of upper limb
0.769 0.231 0.000
B18 Chronic viral hepatitis
0.767 0.233 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.766 0.234 0.000
C81 Hodgkin's disease
0.765 0.235 0.000
O00-O08 Pregnancy with abortive outcome
0.764 0.236 0.000
F30.0 Hypomania
0.764 0.236 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.763 0.237 0.000
E11.3 With ophthalmic complications
0.762 0.238 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.762 0.238 0.000
B44 Aspergillosis
0.759 0.240 0.000
E10.5 With peripheral circulatory complications
0.758 0.242 0.000
O71 Other obstetric trauma
0.758 0.242 0.000
B25-B34 Other viral diseases
0.757 0.242 0.000
C79 Secondary malignant neoplasm of other sites
0.757 0.243 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.755 0.245 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.755 0.245 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.755 0.245 0.000
S50 Superficial injury of forearm
0.754 0.246 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.753 0.247 0.000
F99 Mental disorder, not otherwise specified
0.752 0.248 0.000
M48 Other spondylopathies
0.751 0.249 0.000
E11.8 With unspecified complications
0.750 0.250 0.000
U89 Agent resistant to other and unspecified antibiotics
0.749 0.251 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.748 0.252 0.000
J60-J70 Lung diseases due to external agents
0.747 0.253 0.000
M41 Scoliosis
0.744 0.256 0.000
S81.9 Open wound of lower leg, part unspecified
0.744 0.256 0.000
E11.1 With ketoacidosis
0.743 0.257 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.743 0.257 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
F60-F69 Disorders of adult personality and behaviour
0.741 0.259 0.000
B50-B64 Protozoal diseases
0.741 0.259 0.000
S82 Fracture of lower leg, including ankle
0.741 0.259 0.000
C71.9 Brain, unspecified
0.741 0.259 0.000
Y00-Y09 Assault
0.741 0.259 0.000
C71.2 Temporal lobe
0.741 0.259 0.000
S02.1 Fracture of base of skull
0.740 0.260 0.000
C80 Malignant neoplasm without specification of site
0.740 0.260 0.000
O80-O84 Delivery
0.740 0.260 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.739 0.261 0.000
M54 Dorsalgia
0.739 0.261 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.738 0.262 0.000
E50-E64 Other nutritional deficiencies
0.738 0.262 0.000
S81.8 Open wound of other parts of lower leg
0.738 0.262 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.737 0.263 0.000
M80-M85 Disorders of bone density and structure
0.737 0.263 0.000
O73 Retained placenta and membranes, without haemorrhage
0.736 0.264 0.000
S86 Injury of muscle and tendon at lower leg level
0.735 0.265 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.735 0.265 0.000
E87.3 Alkalosis
0.734 0.266 0.000
C71.1 Frontal lobe
0.734 0.266 0.000
O48 Prolonged pregnancy
0.734 0.266 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.733 0.267 0.000
S06.3 Focal brain injury
0.733 0.267 0.000
D03 Melanoma in situ
0.733 0.267 0.000
W50-W64 Exposure to animate mechanical forces
0.732 0.268 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.732 0.268 0.000
A30-A49 Other bacterial diseases
0.730 0.270 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.729 0.271 0.000
F80-F89 Disorders of psychological development
0.728 0.272 0.000
D05 Carcinoma in situ of breast
0.728 0.272 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.728 0.272 0.000
J98.6 Disorders of diaphragm
0.727 0.273 0.000
B01 Varicella [chickenpox]
0.726 0.274 0.000
O62 Abnormalities of forces of labour
0.726 0.274 0.000
S29 Other and unspecified injuries of thorax
0.725 0.275 0.000
S02.4 Fracture of malar and maxillary bones
0.724 0.276 0.000
C92 Myeloid leukaemia
0.723 0.277 0.000
A80-A89 Viral infections of the central nervous system
0.722 0.277 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.722 0.278 0.000
S59 Other and unspecified injuries of forearm
0.721 0.279 0.000
O63.0 Prolonged first stage (of labour)
0.719 0.281 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.718 0.282 0.000
U88 Agent resistant to multiple antibiotics
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
B37 Candidiasis
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
O74 Complications of anaesthesia during labour and delivery
0.713 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.713 0.287 0.000
O60 Preterm delivery
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
O03 Spontaneous abortion
0.713 0.287 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.711 0.289 0.000
Y98 Lifestyle-related condition
0.711 0.289 0.000
Y97 Environmental-pollution-related condition
0.711 0.289 0.000
Y96 Work-related condition
0.711 0.289 0.000
C53 Malignant neoplasm of cervix uteri
0.710 0.290 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.710 0.290 0.000
T63.4 Venom of other arthropods
0.709 0.291 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.709 0.291 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.708 0.292 0.000
M41.9 Scoliosis, unspecified
0.707 0.293 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.706 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.294 0.000
E10.7 With multiple complications
0.705 0.294 0.000
E10.6 With other specified complications
0.705 0.294 0.000
E10.0 With coma
0.705 0.294 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.295 0.000
F70-F79 Mental retardation
0.705 0.295 0.000
E87.6 Hypokalaemia
0.705 0.295 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.705 0.295 0.000
O41 Other disorders of amniotic fluid and membranes
0.705 0.295 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.704 0.295 0.000
B17 Other acute viral hepatitis
0.704 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
S02.2 Fracture of nasal bones
0.703 0.297 0.000
O85 Puerperal sepsis
0.703 0.297 0.000
C91.0 Acute lymphoblastic leukaemia
0.702 0.298 0.000
E11.7 With multiple complications
0.702 0.298 0.000
Chapter VIII Diseases of the ear and mastoid process
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.700 0.299 0.000
M48.0 Spinal stenosis
0.700 0.300 0.000
O90 Complications of the puerperium, not elsewhere classified
0.700 0.300 0.000
E15 Nondiabetic hypoglycaemic coma
0.700 0.300 0.000
B07 Viral warts
0.699 0.301 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.699 0.301 0.000
F38 Other mood [affective] disorders
0.698 0.302 0.000
F34 Persistent mood [affective] disorders
0.698 0.302 0.000
F39 Unspecified mood [affective] disorder
0.698 0.302 0.000
S10-S19 Injuries to the neck
0.698 0.302 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.698 0.302 0.000
O03.9 Complete or unspecified, without complication
0.697 0.303 0.000
T87 Complications peculiar to reattachment and amputation
0.696 0.303 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.696 0.304 0.000
C48.2 Peritoneum, unspecified
0.696 0.304 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.694 0.306 0.000
F31.8 Other bipolar affective disorders
0.694 0.306 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.694 0.306 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.694 0.306 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.694 0.306 0.000
M50 Cervical disk disorders
0.694 0.306 0.000
S22.0 Fracture of thoracic vertebra
0.694 0.306 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.692 0.308 0.000
E10.9 Without complications
0.692 0.308 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.690 0.310 0.000
D04 Carcinoma in situ of skin
0.690 0.310 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
M00-M03 Infectious arthropathies
0.688 0.312 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.688 0.312 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.688 0.312 0.000
E16.4 Abnormal secretion of gastrin
0.688 0.312 0.000
E16.3 Increased secretion of glucagon
0.688 0.312 0.000
E16.1 Other hypoglycaemia
0.688 0.312 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.688 0.312 0.000
O30 Multiple gestation
0.688 0.312 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.688 0.312 0.000
S22.2 Fracture of sternum
0.686 0.314 0.000
U89.8 Agent resistant to other single specified antibiotic
0.685 0.315 0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.684 0.316 0.000
S05.8 Other injuries of eye and orbit
0.684 0.316 0.000
S20 Superficial injury of thorax
0.683 0.316 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.683 0.317 0.000
S02.5 Fracture of tooth
0.683 0.317 0.000
E13 Other specified diabetes mellitus
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.320 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.679 0.320 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.679 0.321 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.679 0.321 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.678 0.322 0.000
B02.9 Zoster without complication
0.678 0.322 0.000
F30.2 Mania with psychotic symptoms
0.677 0.323 0.000
S08 Traumatic amputation of part of head
0.677 0.323 0.000
S07 Crushing injury of head
0.677 0.323 0.000
S04 Injury of cranial nerves
0.677 0.323 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.677 0.323 0.000
T91 Sequelae of injuries of neck and trunk
0.676 0.324 0.000
E87.0 Hyperosmolality and hypernatraemia
0.676 0.324 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.675 0.325 0.000
J09-J18 Influenza and pneumonia
0.674 0.326 0.000
O66 Other obstructed labour
0.674 0.326 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.674 0.326 0.000
O70.9 Perineal laceration during delivery, unspecified
0.674 0.326 0.000
O70.3 Fourth degree perineal laceration during delivery
0.674 0.326 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.674 0.326 0.000
T85.2 Mechanical complication of intraocular lens
0.673 0.327 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.673 0.327 0.000
E85 Amyloidosis
0.672 0.328 0.000
S58 Traumatic amputation of forearm
0.671 0.329 0.000
S57 Crushing injury of forearm
0.671 0.329 0.000
S55 Injury of blood vessels at forearm level
0.671 0.329 0.000
S54 Injury of nerves at forearm level
0.671 0.329 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.671 0.329 0.000
F05.9 Delirium, unspecified
0.671 0.329 0.000
T58 Toxic effect of carbon monoxide
0.671 0.329 0.000
E46 Unspecified protein-energy malnutrition
0.670 0.329 0.000
J86 Pyothorax
0.670 0.330 0.000
O61 Failed induction of labour
0.670 0.330 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
S52 Fracture of forearm
0.670 0.330 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.670 0.330 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.670 0.330 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.669 0.331 0.000
B44.9 Aspergillosis, unspecified
0.669 0.331 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.669 0.331 0.000
F33 Recurrent depressive disorder
0.668 0.332 0.000
C79.2 Secondary malignant neoplasm of skin
0.667 0.333 0.000
M54.4 Lumbago with sciatica
0.667 0.333 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.666 0.334 0.000
Chapter VI Diseases of the nervous system
0.666 0.334 0.000
B18.2 Chronic viral hepatitis C
0.666 0.334 0.000
M91-M94 Chondropathies
0.665 0.335 0.000
S88 Traumatic amputation of lower leg
0.665 0.335 0.000
S87 Crushing injury of lower leg
0.665 0.335 0.000
S85 Injury of blood vessels at lower leg level
0.665 0.335 0.000
S84 Injury of nerves at lower leg level
0.665 0.335 0.000
S06.5 Traumatic subdural haemorrhage
0.664 0.335 0.000
E88 Other metabolic disorders
0.664 0.336 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.664 0.336 0.000
S06.4 Epidural haemorrhage
0.663 0.337 0.000
S02.8 Fractures of other skull and facial bones
0.663 0.337 0.000
T92.1 Sequelae of fracture of arm
0.663 0.337 0.000
J80 Adult respiratory distress syndrome
0.662 0.338 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.661 0.339 0.000
S02.6 Fracture of mandible
0.660 0.340 0.000
F30.9 Manic episode, unspecified
0.660 0.340 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.660 0.340 0.000
C81.9 Hodgkin's disease, unspecified
0.660 0.340 0.000
S89.9 Unspecified injury of lower leg
0.658 0.342 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.658 0.342 0.000
C69 Malignant neoplasm of eye and adnexa
0.657 0.343 0.000
E73 Lactose intolerance
0.655 0.344 0.000
T93 Sequelae of injuries of lower limb
0.655 0.345 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.652 0.347 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.652 0.347 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.652 0.347 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.651 0.348 0.000
S26 Injury of heart
0.651 0.348 0.000
S25 Injury of blood vessels of thorax
0.651 0.348 0.000
S24 Injury of nerves and spinal cord at thorax level
0.651 0.348 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.651 0.348 0.000
S21 Open wound of thorax
0.651 0.348 0.000
O47 False labour
0.651 0.349 0.000
B65-B83 Helminthiases
0.651 0.349 0.000
T98 Sequelae of other and unspecified effects of external causes
0.651 0.349 0.000
W00-W19 Falls
0.651 0.349 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.650 0.350 0.000
C70 Malignant neoplasm of meninges
0.650 0.350 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.650 0.350 0.000
C58 Malignant neoplasm of placenta
0.650 0.350 0.000
C52 Malignant neoplasm of vagina
0.650 0.350 0.000
S06.2 Diffuse brain injury
0.649 0.351 0.000
E87.2 Acidosis
0.649 0.351 0.000
E10.4 With neurological complications
0.648 0.352 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.648 0.352 0.000
S09 Other and unspecified injuries of head
0.648 0.352 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.647 0.353 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.647 0.353 0.000
F02 Dementia in other diseases classified elsewhere
0.647 0.353 0.000
F09 Unspecified organic or symptomatic mental disorder
0.647 0.353 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.647 0.353 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.647 0.353 0.000
D05.1 Intraductal carcinoma in situ
0.647 0.353 0.000
X23 Contact with hornets, wasps and bees
0.647 0.353 0.000
J96 Respiratory failure, not elsewhere classified
0.645 0.355 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.645 0.355 0.000
S02.10 Fracture of base of skull (closed)
0.644 0.356 0.000
F06.7 Mild cognitive disorder
0.644 0.356 0.000
F05.8 Other delirium
0.644 0.356 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.643 0.357 0.000
B06 Rubella [German measles]
0.643 0.357 0.000
B05 Measles
0.643 0.357 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.643 0.357 0.000
B04 Monkeypox
0.643 0.357 0.000
B03 Smallpox
0.643 0.357 0.000
T81 Complications of procedures, not elsewhere classified
0.642 0.358 0.000
M45 Ankylosing spondylitis
0.641 0.359 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.641 0.359 0.000
S06.9 Intracranial injury, unspecified
0.640 0.360 0.000
C48.0 Retroperitoneum
0.640 0.360 0.000
E84 Cystic fibrosis
0.640 0.360 0.000
E79 Disorders of purine and pyrimidine metabolism
0.640 0.360 0.000
E77 Disorders of glycoprotein metabolism
0.640 0.360 0.000
E76 Disorders of glycosaminoglycan metabolism
0.640 0.360 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.640 0.360 0.000
E72 Other disorders of amino-acid metabolism
0.640 0.360 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.640 0.360 0.000
E70 Disorders of aromatic amino-acid metabolism
0.640 0.360 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.640 0.360 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.639 0.361 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.639 0.361 0.000
J98.3 Compensatory emphysema
0.639 0.361 0.000
J98.2 Interstitial emphysema
0.639 0.361 0.000
F01 Vascular dementia
0.638 0.361 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.637 0.363 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.637 0.363 0.000
M48.09 Spinal stenosis (Site unspecified)
0.637 0.363 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.636 0.364 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.635 0.365 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.635 0.365 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.635 0.365 0.000
C80.9 Malignant neoplasm, unspecified
0.635 0.365 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.634 0.366 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.634 0.366 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.634 0.366 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.634 0.366 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.634 0.366 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.634 0.366 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.634 0.366 0.000
E87.4 Mixed disorder of acid-base balance
0.634 0.366 0.000
G90-G99 Other disorders of the nervous system
0.634 0.366 0.000
B00 Herpesviral [herpes simplex] infections
0.633 0.367 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.633 0.367 0.000
S51.8 Open wound of other parts of forearm
0.632 0.368 0.000
B19 Unspecified viral hepatitis
0.631 0.369 0.000
B16 Acute hepatitis B
0.631 0.369 0.000
M50.0 Cervical disk disorder with myelopathy
0.631 0.369 0.000
S00 Superficial injury of head
0.631 0.369 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.630 0.370 0.000
C95 Leukaemia of unspecified cell type
0.630 0.370 0.000
C94 Other leukaemias of specified cell type
0.630 0.370 0.000
C93 Monocytic leukaemia
0.630 0.370 0.000
C88 Malignant immunoproliferative diseases
0.630 0.370 0.000
C86 Other specified types of T/NK-cell lymphoma
0.630 0.370 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.630 0.370 0.000
T95 Sequelae of burns, corrosions and frostbite
0.630 0.370 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.630 0.370 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.630 0.370 0.000
B48 Other mycoses, not elsewhere classified
0.630 0.370 0.000
B47 Mycetoma
0.630 0.370 0.000
B46 Zygomycosis
0.630 0.370 0.000
B45 Cryptococcosis
0.630 0.370 0.000
B43 Chromomycosis and phaeomycotic abscess
0.630 0.370 0.000
B42 Sporotrichosis
0.630 0.370 0.000
B41 Paracoccidioidomycosis
0.630 0.370 0.000
B40 Blastomycosis
0.630 0.370 0.000
B39 Histoplasmosis
0.630 0.370 0.000
B38 Coccidioidomycosis
0.630 0.370 0.000
B36 Other superficial mycoses
0.630 0.370 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.629 0.371 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.628 0.372 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.628 0.372 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.628 0.372 0.000
O45 Premature separation of placenta [abruptio placentae]
0.627 0.373 0.000
O33 Maternal care for known or suspected disproportion
0.627 0.373 0.000
O31 Complications specific to multiple gestation
0.627 0.373 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.627 0.373 0.000
S02.7 Multiple fractures involving skull and facial bones
0.627 0.373 0.000
B35 Dermatophytosis
0.627 0.373 0.000
S51.9 Open wound of forearm, part unspecified
0.626 0.374 0.000
F03 Unspecified dementia
0.626 0.374 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.626 0.374 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.625 0.374 0.000
F30.8 Other manic episodes
0.625 0.375 0.000
F30.1 Mania without psychotic symptoms
0.625 0.375 0.000
J90-J94 Other diseases of pleura
0.625 0.375 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.624 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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