TreeWAS – Variant ID: rs117489024

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
Chapter IX Diseases of the circulatory system	0.997	0.003
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.996	0.004
M70-M79 Other soft tissue disorders	0.995	0.005
M75 Shoulder lesions	0.993	0.007
Chapter II Neoplasms	0.991	0.009
I30-I52 Other forms of heart disease	0.990	0.010
Chapter I Certain infectious and parasitic diseases	0.990	0.010
Chapter IV Endocrine, nutritional and metabolic diseases	0.987	0.013
M75.4 Impingement syndrome of shoulder	0.984	0.016
E70-E90 Metabolic disorders	0.983	0.017
S80-S89 Injuries to the knee and lower leg	0.982	0.018
E78.0 Pure hypercholesterolaemia	0.980	0.020
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.979	0.021
Chapter XX External causes of morbidity and mortality	0.978	0.022
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.969	0.031
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.966	0.034
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.964	0.036
Chapter VII Diseases of the eye and adnexa	0.962	0.038
D00-D09 In situ neoplasms	0.960	0.040
S82 Fracture of lower leg, including ankle	0.959	0.041
D37-D48 Neoplasms of uncertain or unknown behaviour	0.955	0.045
I42 Cardiomyopathy	0.943	0.057
A30-A49 Other bacterial diseases	0.942	0.058
C60-C63 Malignant neoplasms of male genital organs	0.938	0.062
M75.5 Bursitis of shoulder	0.936	0.064
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.934	0.066
R00 Abnormalities of heart beat	0.934	0.066
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.934	0.066
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.931	0.069
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.928	0.072
R47-R49 Symptoms and signs involving speech and voice	0.922	0.078
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.918	0.082
R30-R39 Symptoms and signs involving the urinary system	0.918	0.082
R06 Abnormalities of breathing	0.915	0.085
D05 Carcinoma in situ of breast	0.913	0.087
I10-I15 Hypertensive diseases	0.913	0.087
R35 Polyuria	0.911	0.089
C61 Malignant neoplasm of prostate	0.895	0.105
M05-M14 Inflammatory polyarthropathies	0.890	0.110
I60-I69 Cerebrovascular diseases	0.890	0.110
R47 Speech disturbances, not elsewhere classified	0.889	0.111
I49 Other cardiac arrhythmias	0.888	0.112
R00.2 Palpitations	0.887	0.113
C50-C50 Malignant neoplasm of breast	0.883	0.117
T39.1 4-Aminophenol derivatives	0.883	0.117
S82.3 Fracture of lower end of tibia	0.877	0.123
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.876	0.124
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.875	0.125
D05.9 Carcinoma in situ of breast, unspecified	0.874	0.126
T43.0 Tricyclic and tetracyclic antidepressants	0.873	0.127
R50-R69 General symptoms and signs	0.873	0.127
R00.1 Bradycardia, unspecified	0.872	0.128
Chapter XV Pregnancy, childbirth and the puerperium	0.871	0.129
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.870	0.130
E87 Other disorders of fluid, electrolyte and acid-base balance	0.869	0.131
A49 Bacterial infection of unspecified site	0.869	0.131
R47.0 Dysphasia and aphasia	0.867	0.133
I10 Essential (primary) hypertension	0.865	0.135
I46 Cardiac arrest	0.864	0.136
D45 Polycythaemia vera	0.858	0.142
S70-S79 Injuries to the hip and thigh	0.857	0.143
S40-S49 Injuries to the shoulder and upper arm	0.857	0.143
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.857	0.143
H04 Disorders of lachrymal system	0.857	0.143
I50 Heart failure	0.857	0.143
S00-S09 Injuries to the head	0.856	0.144
A00-A09 Intestinal infectious diseases	0.856	0.144
H02 Other disorders of eyelid	0.852	0.148
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.852	0.148
M65-M68 Disorders of synovium and tendon	0.852	0.148
R51 Headache	0.851	0.149
R06.0 Dyspnoea	0.842	0.158
B25-B34 Other viral diseases	0.838	0.162
Y43 Primarily systemic agents	0.837	0.163
H30-H36 Disorders of choroid and retina	0.837	0.163
S10-S19 Injuries to the neck	0.835	0.165
T42.4 Benzodiazepines	0.832	0.168
M75.3 Calcific tendinitis of shoulder	0.831	0.169
R41 Other symptoms and signs involving cognitive functions and awareness	0.831	0.169
R44 Other symptoms and signs involving general sensations and perceptions	0.827	0.173
D03 Melanoma in situ	0.823	0.176
I63 Cerebral infarction	0.822	0.178
Y52 Agents primarily affecting the cardiovascular system	0.821	0.179
R06.8 Other and unspecified abnormalities of breathing	0.821	0.179
S82.30 Fracture of lower end of tibia (closed)	0.819	0.181
Y44 Agents primarily affecting blood constituents	0.815	0.185
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.815	0.185
I49.9 Cardiac arrhythmia, unspecified	0.815	0.185
H36 Retinal disorders in diseases classified elsewhere	0.814	0.186
M06 Other rheumatoid arthritis	0.810	0.190
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.809	0.191
I42.9 Cardiomyopathy, unspecified	0.807	0.193
T66-T78 Other and unspecified effects of external causes	0.807	0.193
I42.0 Dilated cardiomyopathy	0.807	0.193
C50 Malignant neoplasm of breast	0.806	0.194
M45-M49 Spondylopathies	0.805	0.195
M80-M85 Disorders of bone density and structure	0.805	0.195
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.803	0.197
A49.0 Staphylococcal infection, unspecified	0.803	0.197
C02 Malignant neoplasm of other and unspecified parts of tongue	0.803	0.197
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.801	0.199
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.799	0.201
S82.1 Fracture of upper end of tibia	0.799	0.201
H36.0 Diabetic retinopathy	0.797	0.203
S89 Other and unspecified injuries of lower leg	0.794	0.206
A08 Viral and other specified intestinal infections	0.793	0.207
Y40 Systemic antibiotics	0.791	0.209
W00-W19 Falls	0.791	0.209
I46.9 Cardiac arrest, unspecified	0.788	0.212
H02.5 Other disorders affecting eyelid function	0.788	0.212
A41 Other septicaemia	0.788	0.212
H53-H54 Visual disturbances and blindness	0.787	0.213
I45 Other conduction disorders	0.787	0.213
I51 Complications and ill-defined descriptions of heart disease	0.786	0.214
M79 Other soft tissue disorders, not elsewhere classified	0.786	0.214
C04 Malignant neoplasm of floor of mouth	0.785	0.215
S82.4 Fracture of fibula alone	0.784	0.216
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.784	0.216
S82.5 Fracture of medial malleolus	0.784	0.216
B95-B98 Bacterial, viral and other infectious agents	0.781	0.219
D04 Carcinoma in situ of skin	0.778	0.222
R63 Symptoms and signs concerning food and fluid intake	0.777	0.223
R05 Cough	0.776	0.224
R06.4 Hyperventilation	0.775	0.225
I47 Paroxysmal tachycardia	0.775	0.225
H02.0 Entropion and trichiasis of eyelid	0.774	0.226
M75.9 Shoulder lesion, unspecified	0.772	0.228
S82.6 Fracture of lateral malleolus	0.771	0.229
I82 Other venous embolism and thrombosis	0.770	0.230
I50.9 Heart failure, unspecified	0.770	0.230
E65-E68 Obesity and other hyperalimentation	0.768	0.232
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.768	0.232
Chapter XXII Codes for special purposes	0.767	0.233
I63.9 Cerebral infarction, unspecified	0.767	0.233
C09 Malignant neoplasm of tonsil	0.766	0.234
R40 Somnolence, stupor and coma	0.766	0.234
M60-M63 Disorders of muscles	0.761	0.239
M65 Synovitis and tenosynovitis	0.759	0.241
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.759	0.241
I49.0 Ventricular fibrillation and flutter	0.759	0.241
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.758	0.242
I36 Nonrheumatic tricuspid valve disorders	0.756	0.243
C50.4 Upper-outer quadrant of breast	0.756	0.244
R32 Unspecified urinary incontinence	0.755	0.245
S42 Fracture of shoulder and upper arm	0.754	0.246
I35 Nonrheumatic aortic valve disorders	0.753	0.247
Chapter VI Diseases of the nervous system	0.752	0.248
M06.9 Rheumatoid arthritis, unspecified	0.751	0.249
I42.1 Obstructive hypertrophic cardiomyopathy	0.751	0.249
H02.8 Other specified disorders of eyelid	0.750	0.250
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.749	0.251
E10-E14 Diabetes mellitus	0.749	0.251
M75.2 Bicipital tendinitis	0.748	0.252
A08.4 Viral intestinal infection, unspecified	0.748	0.252
E87.5 Hyperkalaemia	0.746	0.254
S80 Superficial injury of lower leg	0.746	0.254
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.746	0.254
M71 Other bursopathies	0.743	0.257
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.743	0.257
Y43.3 Other antineoplastic drugs	0.743	0.257
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.743	0.257
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.742	0.258
H04.8 Other disorders of lachrymal system	0.742	0.258
M75.1 Rotator cuff syndrome	0.740	0.260
B15-B19 Viral hepatitis	0.739	0.261
R41.0 Disorientation, unspecified	0.739	0.261
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.737	0.263
T43.2 Other and unspecified antidepressants	0.735	0.265
W20-W49 Exposure to inanimate mechanical forces	0.735	0.265
R03 Abnormal blood-pressure reading, without diagnosis	0.733	0.267
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.732	0.268
Y45.0 Opioids and related analgesics	0.731	0.269
I87 Other disorders of veins	0.731	0.269
I42.8 Other cardiomyopathies	0.730	0.270
V20-V29 Motorcycle rider injured in transport accident	0.730	0.270
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.729	0.271
B34 Viral infection of unspecified site	0.729	0.271
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.728	0.272
C51-C58 Malignant neoplasms of female genital organs	0.727	0.273
M10 Gout	0.727	0.273
B35-B49 Mycoses	0.725	0.274
R60 Oedema, not elsewhere classified	0.725	0.275
A40 Streptococcal septicaemia	0.724	0.275
S70 Superficial injury of hip and thigh	0.724	0.276
D03.3 Melanoma in situ of other and unspecified parts of face	0.724	0.276
S00 Superficial injury of head	0.724	0.276
M00-M03 Infectious arthropathies	0.723	0.277
O94-O99 Other obstetric conditions, not elsewhere classified	0.723	0.277
D09 Carcinoma in situ of other and unspecified sites	0.722	0.278
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.721	0.278
E50-E64 Other nutritional deficiencies	0.721	0.279
S82.8 Fractures of other parts of lower leg	0.721	0.279
M77 Other enthesopathies	0.721	0.279
T15-T19 Effects of foreign body entering through natural orifice	0.720	0.280
C50.9 Breast, unspecified	0.720	0.280
M91-M94 Chondropathies	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
E80 Disorders of porphyrin and bilirubin metabolism	0.716	0.284
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.716	0.284
T46 Poisoning by agents primarily affecting the cardiovascular system	0.716	0.284
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
T36 Poisoning by systemic antibiotics	0.716	0.284
I42.2 Other hypertrophic cardiomyopathy	0.715	0.285
K80.1 Calculus of gallbladder with other cholecystitis	0.715	0.285
I00-I02 Acute rheumatic fever	0.715	0.285
I60 Subarachnoid haemorrhage	0.715	0.285
R95-R99 Ill-defined and unknown causes of mortality	0.714	0.286
M76 Enthesopathies of lower limb, excluding foot	0.714	0.286
M73 Soft tissue disorders in diseases classified elsewhere	0.714	0.286
M70 Soft tissue disorders related to use, overuse and pressure	0.714	0.286
K80 Cholelithiasis	0.712	0.288
M75.8 Other shoulder lesions	0.712	0.288
H04.2 Epiphora	0.712	0.288
Chapter XI Diseases of the digestive system	0.712	0.288
I27 Other pulmonary heart diseases	0.711	0.289
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.711	0.289
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.711	0.289
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.289
Y52.3 Coronary vasodilators, not elsewhere classified	0.711	0.289
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.710	0.290
I52 Other heart disorders in diseases classified elsewhere	0.710	0.290
I48 Atrial fibrillation and flutter	0.710	0.290
I43 Cardiomyopathy in diseases classified elsewhere	0.710	0.290
I41 Myocarditis in diseases classified elsewhere	0.710	0.290
I40 Acute myocarditis	0.710	0.290
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.710	0.290
I37 Pulmonary valve disorders	0.710	0.290
I32 Pericarditis in diseases classified elsewhere	0.710	0.290
I30 Acute pericarditis	0.710	0.290
B99-B99 Other infectious diseases	0.710	0.290
B90-B94 Sequelae of infectious and parasitic diseases	0.710	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.710	0.290
B65-B83 Helminthiases	0.710	0.290
B50-B64 Protozoal diseases	0.710	0.290
B20-B24 Human immunodeficiency virus [HIV] disease	0.710	0.290
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.710	0.290
A80-A89 Viral infections of the central nervous system	0.710	0.290
A75-A79 Rickettsioses	0.710	0.290
A70-A74 Other diseases caused by chlamydiae	0.710	0.290
A65-A69 Other spirochaetal diseases	0.710	0.290
A20-A28 Certain zoonotic bacterial diseases	0.710	0.290
A15-A19 Tuberculosis	0.710	0.290
R30 Pain associated with micturition	0.710	0.290
S06 Intracranial injury	0.710	0.290
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.709	0.291
C02.9 Tongue, unspecified	0.709	0.291
R44.3 Hallucinations, unspecified	0.708	0.292
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.708	0.292
T40.2 Other opioids	0.708	0.292
E40-E46 Malnutrition	0.708	0.292
E87.3 Alkalosis	0.707	0.293
A50-A64 Infections with a predominantly sexual mode of transmission	0.707	0.293
M86-M90 Other osteopathies	0.706	0.294
E78.2 Mixed hyperlipidaemia	0.706	0.294
Y44.2 Anticoagulants	0.705	0.295
E85 Amyloidosis	0.705	0.295
E84 Cystic fibrosis	0.705	0.295
E79 Disorders of purine and pyrimidine metabolism	0.705	0.295
E77 Disorders of glycoprotein metabolism	0.705	0.295
E76 Disorders of glycosaminoglycan metabolism	0.705	0.295
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.705	0.295
E74 Other disorders of carbohydrate metabolism	0.705	0.295
E73 Lactose intolerance	0.705	0.295
E72 Other disorders of amino-acid metabolism	0.705	0.295
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.705	0.295
E70 Disorders of aromatic amino-acid metabolism	0.705	0.295
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.705	0.295
T39.0 Salicylates	0.705	0.295
I61 Intracerebral haemorrhage	0.705	0.295
S82.0 Fracture of patella	0.705	0.295
M40-M43 Deforming dorsopathies	0.704	0.296
S88 Traumatic amputation of lower leg	0.704	0.296
S87 Crushing injury of lower leg	0.704	0.296
S86 Injury of muscle and tendon at lower leg level	0.704	0.296
S85 Injury of blood vessels at lower leg level	0.704	0.296
S84 Injury of nerves at lower leg level	0.704	0.296
D46 Myelodysplastic syndromes	0.703	0.297
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.703	0.297
E86 Volume depletion	0.703	0.297
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.702	0.297
E78.8 Other disorders of lipoprotein metabolism	0.702	0.298
E78.6 Lipoprotein deficiency	0.702	0.298
E78.4 Other hyperlipidaemia	0.702	0.298
E78.3 Hyperchylomicronaemia	0.702	0.298
E78.1 Pure hyperglyceridaemia	0.702	0.298
S90-S99 Injuries to the ankle and foot	0.702	0.298
M50-M54 Other dorsopathies	0.702	0.298
Y45.2 Propionic acid derivatives	0.701	0.298
C62 Malignant neoplasm of testis	0.701	0.298
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.701	0.299
Y35-Y36 Legal intervention and operations of war	0.701	0.299
Y10-Y34 Event of undetermined intent	0.701	0.299
Y00-Y09 Assault	0.701	0.299
X85-X99 Assault	0.701	0.299
X58-X59 Accidental exposure to other and unspecified factors	0.701	0.299
X50-X57 Overexertion, travel and privation	0.701	0.299
X40-X49 Accidental poisoning by and exposure to noxious substances	0.701	0.299
X30-X39 Exposure to forces of nature	0.701	0.299
X20-X29 Contact with venomous animals and plants	0.701	0.299
X10-X19 Contact with heat and hot substances	0.701	0.299
X00-X09 Exposure to smoke, fire and flames	0.701	0.299
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.701	0.299
W75-W84 Other accidental threats to breathing	0.701	0.299
W65-W74 Accidental drowning and submersion	0.701	0.299
W50-W64 Exposure to animate mechanical forces	0.701	0.299
V98-V99 Other and unspecified transport accidents	0.701	0.299
V95-V97 Air and space transport accidents	0.701	0.299
V90-V94 Water transport accidents	0.701	0.299
V80-V89 Other land transport accidents	0.701	0.299
V70-V79 Bus occupant injured in transport accident	0.701	0.299
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.701	0.299
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.701	0.299
V40-V49 Car occupant injured in transport accident	0.701	0.299
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.701	0.299
V01-V09 Pedestrian injured in transport accident	0.701	0.299
E20-E35 Disorders of other endocrine glands	0.701	0.299
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.700	0.300
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.700	0.300
Y60-Y69 Misadventures to patients during surgical and medical care	0.699	0.301
C01 Malignant neoplasm of base of tongue	0.698	0.302
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.698	0.302
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.698	0.302
D41.4 Bladder	0.698	0.302
I33 Acute and subacute endocarditis	0.698	0.302
S14 Injury of nerves and spinal cord at neck level	0.697	0.303
T79-T79 Certain early complications of trauma	0.697	0.303
R41.3 Other amnesia	0.697	0.303
M05 Seropositive rheumatoid arthritis	0.695	0.305
Chapter VIII Diseases of the ear and mastoid process	0.695	0.305
Y59 Other and unspecified vaccines and biological substances	0.695	0.305
Y58 Bacterial vaccines	0.695	0.305
Y57 Other and unspecified drugs and medicaments	0.695	0.305
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.695	0.305
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.695	0.305
Y53 Agents primarily affecting the gastro-intestinal system	0.695	0.305
Y50 Central nervous system stimulants, not elsewhere classified	0.695	0.305
Y49 Psychotropic drugs, not elsewhere classified	0.695	0.305
Y48 Anaesthetics and therapeutic gases	0.695	0.305
Y47 Sedatives, hypnotics and antianxiety drugs	0.695	0.305
Y46 Antiepileptics and anti-Parkinsonism drugs	0.695	0.305
Y41 Other systemic anti-infectives and antiparasitics	0.695	0.305
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.695	0.305
S20-S29 Injuries to the thorax	0.695	0.305
R63.0 Anorexia	0.695	0.305
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.694	0.305
H04.1 Other disorders of lachrymal gland	0.693	0.307
D05.1 Intraductal carcinoma in situ	0.693	0.307
M47 Spondylosis	0.692	0.308
T40.4 Other synthetic narcotics	0.692	0.308
S81 Open wound of lower leg	0.691	0.309
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.691	0.309
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.691	0.309
T39.4 Antirheumatics, not elsewhere classified	0.691	0.309
T39.2 Pyrazolone derivatives	0.691	0.309
H46-H48 Disorders of optic nerve and visual pathways	0.690	0.310
M65.9 Synovitis and tenosynovitis, unspecified	0.689	0.311
D02 Carcinoma in situ of middle ear and respiratory system	0.688	0.312
D01 Carcinoma in situ of other and unspecified digestive organs	0.688	0.312
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.688	0.312
S82.9 Fracture of lower leg, part unspecified	0.688	0.312
S82.7 Multiple fractures of lower leg	0.688	0.312
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.687	0.313
R34 Anuria and oliguria	0.686	0.314
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.685	0.315
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.685	0.315
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.685	0.315
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.685	0.315
Q80-Q89 Other congenital malformations	0.684	0.316
S82.10 Fracture of upper end of tibia (closed)	0.684	0.316
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.683	0.317
H55-H59 Other disorders of eye and adnexa	0.682	0.318
Y51 Drugs primarily affecting the autonomic nervous system	0.682	0.318
E87.6 Hypokalaemia	0.680	0.320
C04.9 Floor of mouth, unspecified	0.679	0.321
H43-H45 Disorders of vitreous body and globe	0.679	0.321
I82.8 Embolism and thrombosis of other specified veins	0.679	0.321
M84 Disorders of continuity of bone	0.678	0.322
I51.7 Cardiomegaly	0.678	0.322
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.676	0.323
I42.7 Cardiomyopathy due to drugs and other external agents	0.676	0.324
I42.6 Alcoholic cardiomyopathy	0.676	0.324
I42.5 Other restrictive cardiomyopathy	0.676	0.324
I42.4 Endocardial fibroelastosis	0.676	0.324
I42.3 Endomyocardial (eosinophilic) disease	0.676	0.324
Chapter XII Diseases of the skin and subcutaneous tissue	0.676	0.324
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.676	0.324
S79 Other and unspecified injuries of hip and thigh	0.676	0.324
A48 Other bacterial diseases, not elsewhere classified	0.675	0.325
A44 Bartonellosis	0.675	0.325
A43 Nocardiosis	0.675	0.325
A42 Actinomycosis	0.675	0.325
A39 Meningococcal infection	0.675	0.325
A37 Whooping cough	0.675	0.325
A36 Diphtheria	0.675	0.325
A32 Listeriosis	0.675	0.325
A31 Infection due to other mycobacteria	0.675	0.325
A30 Leprosy [Hansen's disease]	0.675	0.325
A46 Erysipelas	0.675	0.325
A38 Scarlet fever	0.675	0.325
A35 Other tetanus	0.675	0.325
A34 Obstetrical tetanus	0.675	0.325
A33 Tetanus neonatorum	0.675	0.325
R06.2 Wheezing	0.675	0.325
K80.0 Calculus of gallbladder with acute cholecystitis	0.675	0.325
R01 Cardiac murmurs and other cardiac sounds	0.675	0.325
A49.8 Other bacterial infections of unspecified site	0.674	0.326
X60-X84 Intentional self-harm	0.674	0.326
R44.0 Auditory hallucinations	0.674	0.326
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.674	0.326
I83 Varicose veins of lower extremities	0.673	0.327
E83 Disorders of mineral metabolism	0.672	0.327
C63 Malignant neoplasm of other and unspecified male genital organs	0.672	0.328
C60 Malignant neoplasm of penis	0.672	0.328
R52 Pain, not elsewhere classified	0.671	0.329
T43.9 Psychotropic drug, unspecified	0.670	0.330
T43.8 Other psychotropic drugs, not elsewhere classified	0.670	0.330
T43.6 Psychostimulants with abuse potential	0.670	0.330
T43.5 Other and unspecified antipsychotics and neuroleptics	0.670	0.330
T43.4 Butyrophenone and thioxanthene neuroleptics	0.670	0.330
T43.3 Phenothiazine antipsychotics and neuroleptics	0.670	0.330
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.670	0.330
R58 Haemorrhage, not elsewhere classified	0.670	0.330
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.670	0.330
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.669	0.331
C13 Malignant neoplasm of hypopharynx	0.669	0.331
C11 Malignant neoplasm of nasopharynx	0.669	0.331
C10 Malignant neoplasm of oropharynx	0.669	0.331
C08 Malignant neoplasm of other and unspecified major salivary glands	0.669	0.331
C06 Malignant neoplasm of other and unspecified parts of mouth	0.669	0.331
C05 Malignant neoplasm of palate	0.669	0.331
C03 Malignant neoplasm of gum	0.669	0.331
C00 Malignant neoplasm of lip	0.669	0.331
C12 Malignant neoplasm of pyriform sinus	0.669	0.331
C07 Malignant neoplasm of parotid gland	0.669	0.331
H53 Visual disturbances	0.669	0.331
E87.0 Hyperosmolality and hypernatraemia	0.669	0.331
T78 Adverse effects, not elsewhere classified	0.668	0.332
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.668	0.332
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.668	0.332
T42.5 Mixed antiepileptics, not elsewhere classified	0.668	0.332
T42.3 Barbiturates	0.668	0.332
T42.2 Succinimides and oxazolidinediones	0.668	0.332
T42.1 Iminostilbenes	0.668	0.332
T42.0 Hydantoin derivatives	0.668	0.332
S49 Other and unspecified injuries of shoulder and upper arm	0.666	0.333
I69 Sequelae of cerebrovascular disease	0.666	0.334
O85-O92 Complications predominantly related to the puerperium	0.666	0.334
H05 Disorders of orbit	0.665	0.334
H03 Disorders of eyelid in diseases classified elsewhere	0.665	0.334
A41.9 Septicaemia, unspecified	0.665	0.335
I31 Other diseases of pericardium	0.665	0.335
M79.1 Myalgia	0.664	0.336
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.664	0.336
I49.3 Ventricular premature depolarisation	0.663	0.337
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.661	0.339
I95-I99 Other and unspecified disorders of the circulatory system	0.661	0.339
A41.1 Septicaemia due to other specified staphylococcus	0.660	0.340
S89.9 Unspecified injury of lower leg	0.660	0.340
S82.40 Fracture of fibula alone (closed)	0.659	0.341
E87.1 Hypo-osmolality and hyponatraemia	0.659	0.341
Q38-Q45 Other congenital malformations of the digestive system	0.658	0.342
R46 Symptoms and signs involving appearance and behaviour	0.658	0.342
R43 Disturbances of smell and taste	0.658	0.342
R36 Urethral discharge	0.658	0.342
S82.50 Fracture of medial malleolus (closed)	0.658	0.342
S05 Injury of eye and orbit	0.658	0.342
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.658	0.342
R06.7 Sneezing	0.656	0.344
R06.6 Hiccough	0.656	0.344
R06.3 Periodic breathing	0.656	0.344
R06.1 Stridor	0.656	0.344
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.656	0.344
D05.7 Other carcinoma in situ of breast	0.655	0.345
D05.0 Lobular carcinoma in situ	0.655	0.345
S46 Injury of muscle and tendon at shoulder and upper arm level	0.655	0.345
I15 Secondary hypertension	0.654	0.345
I13 Hypertensive heart and renal disease	0.654	0.345
I11 Hypertensive heart disease	0.654	0.345
Y40.0 Penicillins	0.654	0.346
S09 Other and unspecified injuries of head	0.654	0.346
I44 Atrioventricular and left bundle-branch block	0.654	0.346
R03.1 Nonspecific low blood-pressure reading	0.653	0.347
G40-G47 Episodic and paroxysmal disorders	0.652	0.348
R82 Other abnormal findings in urine	0.651	0.349
B34.9 Viral infection, unspecified	0.651	0.349
O34 Maternal care for known or suspected abnormality of pelvic organs	0.651	0.349

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations