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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117675380
log Bayes Factor = 13.6306
Chromosome 18   position 811,672  (GRCh37) Explore rs117675380 on Ensembl!
Variant rs117675380 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.991 0.009 0.000
I60-I69 Cerebrovascular diseases
0.988 0.012 0.000
I30-I52 Other forms of heart disease
0.984 0.016 0.000
I63 Cerebral infarction
0.977 0.023 0.000
M70-M79 Other soft tissue disorders
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.972 0.028 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.969 0.031 0.000
I63.9 Cerebral infarction, unspecified
0.968 0.032 0.000
I47 Paroxysmal tachycardia
0.968 0.032 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
M75 Shoulder lesions
0.966 0.034 0.000
Chapter II Neoplasms
0.959 0.041 0.000
C15-C26 Malignant neoplasms of digestive organs
0.954 0.046 0.000
I51 Complications and ill-defined descriptions of heart disease
0.949 0.051 0.000
I47.2 Ventricular tachycardia
0.947 0.053 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.939 0.061 0.000
S01 Open wound of head
0.938 0.062 0.000
M75.1 Rotator cuff syndrome
0.938 0.062 0.000
H30-H36 Disorders of choroid and retina
0.934 0.066 0.000
M45-M49 Spondylopathies
0.934 0.066 0.000
Chapter I Certain infectious and parasitic diseases
0.930 0.070 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.929 0.071 0.000
C18 Malignant neoplasm of colon
0.923 0.077 0.000
I51.8 Other ill-defined heart diseases
0.922 0.078 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.920 0.080 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.918 0.082 0.000
M05-M14 Inflammatory polyarthropathies
0.908 0.092 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.906 0.094 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.896 0.104 0.000
I21 Acute myocardial infarction
0.887 0.113 0.000
M47 Spondylosis
0.886 0.114 0.000
M75.4 Impingement syndrome of shoulder
0.883 0.117 0.000
Chapter V Mental and behavioural disorders
0.880 0.120 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.872 0.128 0.000
S01.0 Open wound of scalp
0.871 0.129 0.000
I05-I09 Chronic rheumatic heart diseases
0.868 0.132 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.867 0.133 0.000
Chapter X Diseases of the respiratory system
0.864 0.136 0.000
I25.2 Old myocardial infarction
0.858 0.142 0.000
M20-M25 Other joint disorders
0.857 0.143 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.857 0.143 0.000
C18.9 Colon, unspecified
0.855 0.145 0.000
Chapter VIII Diseases of the ear and mastoid process
0.855 0.145 0.000
S80-S89 Injuries to the knee and lower leg
0.851 0.149 0.000
M47.9 Spondylosis, unspecified
0.849 0.151 0.000
J90-J94 Other diseases of pleura
0.846 0.154 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.840 0.160 0.000
M06 Other rheumatoid arthritis
0.839 0.161 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.839 0.161 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.838 0.162 0.000
H33 Retinal detachments and breaks
0.838 0.162 0.000
I60 Subarachnoid haemorrhage
0.837 0.163 0.000
O60-O75 Complications of labour and delivery
0.836 0.164 0.000
I10-I15 Hypertensive diseases
0.833 0.167 0.000
I22 Subsequent myocardial infarction
0.832 0.168 0.000
C18.2 Ascending colon
0.830 0.170 0.000
H53-H54 Visual disturbances and blindness
0.825 0.174 0.000
T66-T78 Other and unspecified effects of external causes
0.825 0.175 0.000
I78 Diseases of capillaries
0.824 0.176 0.000
I42 Cardiomyopathy
0.822 0.178 0.000
H43-H45 Disorders of vitreous body and globe
0.822 0.178 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.822 0.178 0.000
H10-H13 Disorders of conjunctiva
0.821 0.179 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.821 0.179 0.000
I51.7 Cardiomegaly
0.819 0.181 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.818 0.182 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.817 0.183 0.000
Chapter VI Diseases of the nervous system
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.814 0.186 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.812 0.188 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.812 0.188 0.000
H34 Retinal vascular occlusions
0.806 0.194 0.000
F30-F39 Mood [affective] disorders
0.805 0.195 0.000
M50-M54 Other dorsopathies
0.804 0.196 0.000
C16 Malignant neoplasm of stomach
0.803 0.197 0.000
H35 Other retinal disorders
0.803 0.197 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.803 0.197 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.802 0.198 0.000
W00-W19 Falls
0.802 0.198 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.801 0.199 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.798 0.202 0.000
I47.0 Reentry ventricular arrhythmia
0.797 0.203 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.795 0.205 0.000
I49 Other cardiac arrhythmias
0.792 0.208 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.791 0.209 0.000
I21.4 Acute subendocardial myocardial infarction
0.791 0.209 0.000
T81 Complications of procedures, not elsewhere classified
0.791 0.209 0.000
M75.2 Bicipital tendinitis
0.791 0.209 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
J93 Pneumothorax
0.787 0.213 0.000
Y52 Agents primarily affecting the cardiovascular system
0.786 0.214 0.000
I34 Nonrheumatic mitral valve disorders
0.786 0.214 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.785 0.215 0.000
M06.9 Rheumatoid arthritis, unspecified
0.785 0.215 0.000
M65-M68 Disorders of synovium and tendon
0.782 0.218 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.781 0.219 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.780 0.220 0.000
M40-M43 Deforming dorsopathies
0.779 0.221 0.000
S60-S69 Injuries to the wrist and hand
0.777 0.223 0.000
A00-A09 Intestinal infectious diseases
0.774 0.226 0.000
M77 Other enthesopathies
0.774 0.226 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.773 0.227 0.000
S02 Fracture of skull and facial bones
0.773 0.227 0.000
H55-H59 Other disorders of eye and adnexa
0.773 0.227 0.000
H33.3 Retinal breaks without detachment
0.772 0.228 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.772 0.228 0.000
A30-A49 Other bacterial diseases
0.771 0.229 0.000
C64-C68 Malignant neoplasms of urinary tract
0.770 0.230 0.000
M24 Other specific joint derangements
0.770 0.230 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.768 0.232 0.000
I05 Rheumatic mitral valve diseases
0.767 0.233 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.766 0.234 0.000
S70-S79 Injuries to the hip and thigh
0.765 0.235 0.000
M86-M90 Other osteopathies
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
F31 Bipolar affective disorder
0.764 0.236 0.000
C25 Malignant neoplasm of pancreas
0.764 0.236 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.763 0.237 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.762 0.238 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.762 0.238 0.000
O00-O08 Pregnancy with abortive outcome
0.757 0.243 0.000
S01.3 Open wound of ear
0.756 0.243 0.000
M91-M94 Chondropathies
0.756 0.244 0.000
C17 Malignant neoplasm of small intestine
0.754 0.245 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.753 0.247 0.000
I12 Hypertensive renal disease
0.752 0.248 0.000
S06 Intracranial injury
0.752 0.248 0.000
I61 Intracerebral haemorrhage
0.750 0.250 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.750 0.250 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.748 0.252 0.000
C20 Malignant neoplasm of rectum
0.748 0.252 0.000
J60-J70 Lung diseases due to external agents
0.745 0.255 0.000
I25.5 Ischaemic cardiomyopathy
0.745 0.255 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.744 0.256 0.000
J93.9 Pneumothorax, unspecified
0.743 0.257 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.743 0.257 0.000
D46 Myelodysplastic syndromes
0.743 0.257 0.000
E10-E14 Diabetes mellitus
0.742 0.258 0.000
H35.8 Other specified retinal disorders
0.742 0.258 0.000
S10-S19 Injuries to the neck
0.741 0.259 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.740 0.260 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.739 0.261 0.000
S01.8 Open wound of other parts of head
0.739 0.261 0.000
M54 Dorsalgia
0.737 0.263 0.000
M75.9 Shoulder lesion, unspecified
0.736 0.264 0.000
X60-X84 Intentional self-harm
0.735 0.264 0.000
I69 Sequelae of cerebrovascular disease
0.735 0.265 0.000
I77 Other disorders of arteries and arterioles
0.733 0.267 0.000
B65-B83 Helminthiases
0.733 0.267 0.000
S01.9 Open wound of head, part unspecified
0.733 0.267 0.000
C22.9 Liver, unspecified
0.732 0.267 0.000
C18.6 Descending colon
0.732 0.268 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.731 0.269 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.731 0.269 0.000
S80 Superficial injury of lower leg
0.731 0.269 0.000
I49.0 Ventricular fibrillation and flutter
0.729 0.271 0.000
Y44 Agents primarily affecting blood constituents
0.729 0.271 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.729 0.271 0.000
M47.2 Other spondylosis with radiculopathy
0.729 0.271 0.000
H33.5 Other retinal detachments
0.729 0.271 0.000
T79-T79 Certain early complications of trauma
0.729 0.271 0.000
Chapter XXII Codes for special purposes
0.729 0.271 0.000
M00-M03 Infectious arthropathies
0.729 0.271 0.000
S01.7 Multiple open wounds of head
0.728 0.272 0.000
I33 Acute and subacute endocarditis
0.727 0.273 0.000
T31 Burns classified according to extent of body surface involved
0.725 0.274 0.000
H49 Paralytic strabismus
0.725 0.275 0.000
I62 Other nontraumatic intracranial haemorrhage
0.725 0.275 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.725 0.275 0.000
J20-J22 Other acute lower respiratory infections
0.724 0.276 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.724 0.276 0.000
S01.5 Open wound of lip and oral cavity
0.724 0.276 0.000
M23 Internal derangement of knee
0.723 0.277 0.000
M48 Other spondylopathies
0.722 0.278 0.000
M71 Other bursopathies
0.722 0.278 0.000
B35-B49 Mycoses
0.721 0.279 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.720 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.715 0.285 0.000
H34.8 Other retinal vascular occlusions
0.714 0.286 0.000
J92 Pleural plaque
0.714 0.286 0.000
M80-M85 Disorders of bone density and structure
0.713 0.287 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.291 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.708 0.292 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.708 0.292 0.000
I78.1 Naevus, nonneoplastic
0.707 0.293 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.707 0.293 0.000
H43 Disorders of vitreous body
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.294 0.000
I48 Atrial fibrillation and flutter
0.706 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.294 0.000
I40 Acute myocarditis
0.706 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.294 0.000
I37 Pulmonary valve disorders
0.706 0.294 0.000
I36 Nonrheumatic tricuspid valve disorders
0.706 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.294 0.000
B95-B98 Bacterial, viral and other infectious agents
0.705 0.294 0.000
V80-V89 Other land transport accidents
0.705 0.295 0.000
O80-O84 Delivery
0.705 0.295 0.000
M21 Other acquired deformities of limbs
0.705 0.295 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.705 0.295 0.000
H90-H95 Other disorders of ear
0.704 0.296 0.000
E11 Non-insulin-dependent diabetes mellitus
0.703 0.297 0.000
C18.0 Caecum
0.701 0.298 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.701 0.299 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.701 0.299 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.701 0.299 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.701 0.299 0.000
M76 Enthesopathies of lower limb, excluding foot
0.701 0.299 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.701 0.299 0.000
T78 Adverse effects, not elsewhere classified
0.700 0.300 0.000
C18.5 Splenic flexure
0.699 0.301 0.000
O72 Postpartum haemorrhage
0.699 0.301 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
C45 Mesothelioma
0.698 0.302 0.000
J90 Pleural effusion, not elsewhere classified
0.698 0.302 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.698 0.302 0.000
M54.3 Sciatica
0.698 0.302 0.000
H01 Other inflammation of eyelid
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.303 0.000
Y10-Y34 Event of undetermined intent
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
X85-X99 Assault
0.697 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
X30-X39 Exposure to forces of nature
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.303 0.000
W75-W84 Other accidental threats to breathing
0.697 0.303 0.000
W65-W74 Accidental drowning and submersion
0.697 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.303 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
V90-V94 Water transport accidents
0.697 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.303 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.697 0.303 0.000
M13 Other arthritis
0.695 0.305 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.695 0.305 0.000
T87 Complications peculiar to reattachment and amputation
0.695 0.305 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.695 0.305 0.000
C43 Malignant melanoma of skin
0.694 0.306 0.000
I30 Acute pericarditis
0.694 0.306 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.693 0.307 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S05 Injury of eye and orbit
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.693 0.307 0.000
M75.8 Other shoulder lesions
0.693 0.307 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.692 0.308 0.000
H53 Visual disturbances
0.692 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.691 0.309 0.000
H11 Other disorders of conjunctiva
0.690 0.310 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.688 0.312 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.688 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.312 0.000
J94 Other pleural conditions
0.688 0.312 0.000
I71 Aortic aneurysm and dissection
0.687 0.313 0.000
C22.0 Liver cell carcinoma
0.687 0.313 0.000
M75.5 Bursitis of shoulder
0.687 0.313 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.687 0.313 0.000
I47.1 Supraventricular tachycardia
0.687 0.313 0.000
T86 Failure and rejection of transplanted organs and tissues
0.686 0.313 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.685 0.315 0.000
C15 Malignant neoplasm of oesophagus
0.684 0.315 0.000
I44 Atrioventricular and left bundle-branch block
0.684 0.316 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.684 0.316 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.684 0.316 0.000
C21 Malignant neoplasm of anus and anal canal
0.684 0.316 0.000
C23 Malignant neoplasm of gallbladder
0.684 0.316 0.000
S01.1 Open wound of eyelid and periocular area
0.682 0.318 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.682 0.318 0.000
M75.0 Adhesive capsulitis of shoulder
0.682 0.318 0.000
H60-H62 Diseases of external ear
0.681 0.318 0.000
C18.4 Transverse colon
0.681 0.319 0.000
V20-V29 Motorcycle rider injured in transport accident
0.681 0.319 0.000
T18 Foreign body in alimentary tract
0.681 0.319 0.000
I51.6 Cardiovascular disease, unspecified
0.680 0.319 0.000
I51.5 Myocardial degeneration
0.680 0.319 0.000
I51.4 Myocarditis, unspecified
0.680 0.319 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.680 0.319 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.680 0.319 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.680 0.319 0.000
I51.0 Cardiac septal defect, acquired
0.680 0.319 0.000
Q60-Q64 Congenital malformations of the urinary system
0.680 0.320 0.000
C18.3 Hepatic flexure
0.680 0.320 0.000
I72 Other aneurysm
0.679 0.321 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.679 0.321 0.000
I08 Multiple valve diseases
0.678 0.322 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.677 0.323 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.677 0.323 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
E11.9 Without complications
0.674 0.326 0.000
M46 Other inflammatory spondylopathies
0.673 0.327 0.000
Y59 Other and unspecified vaccines and biological substances
0.673 0.327 0.000
Y58 Bacterial vaccines
0.673 0.327 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.673 0.327 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.327 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.673 0.327 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.673 0.327 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.673 0.327 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.673 0.327 0.000
Y48 Anaesthetics and therapeutic gases
0.673 0.327 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.673 0.327 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.673 0.327 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
S01.4 Open wound of cheek and temporomandibular area
0.673 0.327 0.000
I15 Secondary hypertension
0.672 0.328 0.000
B15-B19 Viral hepatitis
0.672 0.328 0.000
Y45.0 Opioids and related analgesics
0.672 0.328 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.670 0.330 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.670 0.330 0.000
H31 Other disorders of choroid
0.670 0.330 0.000
H30 Chorioretinal inflammation
0.670 0.330 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.330 0.000
M49 Spondylopathies in diseases classified elsewhere
0.669 0.330 0.000
I05.2 Mitral stenosis with insufficiency
0.669 0.331 0.000
S09 Other and unspecified injuries of head
0.669 0.331 0.000
I70 Atherosclerosis
0.669 0.331 0.000
M07 Psoriatic and enteropathic arthropathies
0.668 0.332 0.000
H52 Disorders of refraction and accommodation
0.668 0.332 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.667 0.333 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.667 0.333 0.000
H65-H75 Diseases of middle ear and mastoid
0.667 0.333 0.000
B99-B99 Other infectious diseases
0.666 0.333 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.666 0.333 0.000
B50-B64 Protozoal diseases
0.666 0.333 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.666 0.333 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.666 0.333 0.000
A80-A89 Viral infections of the central nervous system
0.666 0.333 0.000
A75-A79 Rickettsioses
0.666 0.333 0.000
A70-A74 Other diseases caused by chlamydiae
0.666 0.333 0.000
A65-A69 Other spirochaetal diseases
0.666 0.333 0.000
A20-A28 Certain zoonotic bacterial diseases
0.666 0.333 0.000
A15-A19 Tuberculosis
0.666 0.333 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.666 0.334 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.666 0.334 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.666 0.334 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.666 0.334 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.666 0.334 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.666 0.334 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.666 0.334 0.000
T36 Poisoning by systemic antibiotics
0.666 0.334 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.666 0.334 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.665 0.335 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.664 0.336 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.663 0.337 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.663 0.337 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.662 0.338 0.000
F80-F89 Disorders of psychological development
0.662 0.338 0.000
C18.8 Overlapping lesion of colon
0.661 0.338 0.000
C18.1 Appendix
0.661 0.338 0.000
C22.1 Intrahepatic bile duct carcinoma
0.661 0.339 0.000
S81 Open wound of lower leg
0.661 0.339 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.661 0.339 0.000
J69 Pneumonitis due to solids and liquids
0.660 0.340 0.000
M11 Other crystal arthropathies
0.660 0.340 0.000
M24.1 Other articular cartilage disorders
0.659 0.341 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.658 0.342 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.658 0.342 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.658 0.342 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.658 0.342 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.658 0.342 0.000
M05 Seropositive rheumatoid arthritis
0.658 0.342 0.000
I42.9 Cardiomyopathy, unspecified
0.657 0.343 0.000
S50-S59 Injuries to the elbow and forearm
0.657 0.343 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.656 0.344 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.656 0.344 0.000
M65 Synovitis and tenosynovitis
0.655 0.345 0.000
W20-W49 Exposure to inanimate mechanical forces
0.655 0.345 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.655 0.345 0.000
Y57 Other and unspecified drugs and medicaments
0.654 0.345 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.654 0.346 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.653 0.347 0.000
F31.9 Bipolar affective disorder, unspecified
0.653 0.347 0.000
O66 Other obstructed labour
0.651 0.348 0.000
E20-E35 Disorders of other endocrine glands
0.651 0.348 0.000
T43.2 Other and unspecified antidepressants
0.651 0.349 0.000
M14 Arthropathies in other diseases classified elsewhere
0.651 0.349 0.000
M12 Other specific arthropathies
0.651 0.349 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.651 0.349 0.000
M08 Juvenile arthritis
0.651 0.349 0.000
I38 Endocarditis, valve unspecified
0.651 0.349 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.651 0.349 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.650 0.350 0.000
M72 Fibroblastic disorders
0.650 0.350 0.000
C16.0 Cardia
0.650 0.350 0.000
I12.0 Hypertensive renal disease with renal failure
0.650 0.350 0.000
O85-O92 Complications predominantly related to the puerperium
0.650 0.350 0.000
G90-G99 Other disorders of the nervous system
0.649 0.351 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.649 0.351 0.000
C92 Myeloid leukaemia
0.647 0.353 0.000
H05 Disorders of orbit
0.647 0.353 0.000
M24.5 Contracture of joint
0.646 0.353 0.000
S32 Fracture of lumbar spine and pelvis
0.646 0.354 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.645 0.355 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.645 0.355 0.000
O62 Abnormalities of forces of labour
0.644 0.355 0.000
C51-C58 Malignant neoplasms of female genital organs
0.644 0.355 0.000
H49.2 Sixth [abducent] nerve palsy
0.644 0.356 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.644 0.356 0.000
T31.0 Burns involving less than 10% of body surface
0.643 0.357 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.643 0.357 0.000
C16.9 Stomach, unspecified
0.643 0.357 0.000
T92 Sequelae of injuries of upper limb
0.643 0.357 0.000
O61 Failed induction of labour
0.642 0.358 0.000
H35.6 Retinal haemorrhage
0.641 0.359 0.000
M54.39 Sciatica (Site unspecified)
0.640 0.360 0.000
T51 Toxic effect of alcohol
0.638 0.361 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.637 0.363 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.636 0.364 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.636 0.364 0.000
I63.8 Other cerebral infarction
0.636 0.364 0.000
C25.9 Pancreas, unspecified
0.635 0.365 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.635 0.365 0.000
M47.1 Other spondylosis with myelopathy
0.635 0.365 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.635 0.365 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.635 0.365 0.000
I11 Hypertensive heart disease
0.635 0.365 0.000
I45 Other conduction disorders
0.634 0.366 0.000
I12.9 Hypertensive renal disease without renal failure
0.633 0.367 0.000
T59 Toxic effect of other gases, fumes and vapours
0.633 0.367 0.000
I77.1 Stricture of artery
0.633 0.367 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.632 0.368 0.000
I34.1 Mitral (valve) prolapse
0.632 0.368 0.000
W17 Other fall from one level to another
0.632 0.368 0.000
I73 Other peripheral vascular diseases
0.632 0.368 0.000
F99-F99 Unspecified mental disorder
0.631 0.369 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.631 0.369 0.000
F70-F79 Mental retardation
0.631 0.369 0.000
F60-F69 Disorders of adult personality and behaviour
0.631 0.369 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.631 0.369 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.631 0.369 0.000
S61 Open wound of wrist and hand
0.630 0.370 0.000
S91 Open wound of ankle and foot
0.630 0.370 0.000
H55 Nystagmus and other irregular eye movements
0.629 0.371 0.000
Y95 Nosocomial condition
0.628 0.372 0.000
M77.1 Lateral epicondylitis
0.628 0.372 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.627 0.373 0.000
S89 Other and unspecified injuries of lower leg
0.627 0.373 0.000
I21.9 Acute myocardial infarction, unspecified
0.626 0.374 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.625 0.375 0.000
Y45.8 Other analgesics and antipyretics
0.625 0.375 0.000
Y45.5 4-Aminophenol derivatives
0.625 0.375 0.000
Y45.4 Antirheumatics
0.625 0.375 0.000
Y45.2 Propionic acid derivatives
0.625 0.375 0.000
Y45.1 Salicylates
0.625 0.375 0.000
M86 Osteomyelitis
0.625 0.375 0.000
I46 Cardiac arrest
0.624 0.375 0.000
I24 Other acute ischaemic heart diseases
0.624 0.376 0.000
J22 Unspecified acute lower respiratory infection
0.624 0.376 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.623 0.377 0.000
M06.0 Seronegative rheumatoid arthritis
0.623 0.377 0.000
W18 Other fall on same level
0.622 0.378 0.000
I09 Other rheumatic heart diseases
0.622 0.378 0.000
I06 Rheumatic aortic valve diseases
0.622 0.378 0.000
S20-S29 Injuries to the thorax
0.622 0.378 0.000
T43.9 Psychotropic drug, unspecified
0.622 0.378 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.622 0.378 0.000
T43.6 Psychostimulants with abuse potential
0.622 0.378 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.622 0.378 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.622 0.378 0.000
I74 Arterial embolism and thrombosis
0.622 0.378 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.621 0.379 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.621 0.379 0.000
O02 Other abnormal products of conception
0.620 0.380 0.000
M54.1 Radiculopathy
0.619 0.381 0.000
H54 Blindness and low vision
0.619 0.381 0.000
I49.3 Ventricular premature depolarisation
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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