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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117863495
log Bayes Factor = 14.7593
Chromosome 12   position 129,432,374  (GRCh37) Explore rs117863495 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
E70-E90 Metabolic disorders
0.988 0.012 0.000
F30-F39 Mood [affective] disorders
0.987 0.013 0.000
D60-D64 Aplastic and other anaemias
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.985 0.015 0.000
D64 Other anaemias
0.978 0.022 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.974 0.026 0.000
D64.9 Anaemia, unspecified
0.972 0.028 0.000
Chapter II Neoplasms
0.971 0.029 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.969 0.031 0.000
I20 Angina pectoris
0.965 0.035 0.000
Chapter VI Diseases of the nervous system
0.965 0.035 0.000
S80-S89 Injuries to the knee and lower leg
0.964 0.036 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.958 0.042 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.952 0.048 0.000
C15-C26 Malignant neoplasms of digestive organs
0.952 0.048 0.000
I25.2 Old myocardial infarction
0.950 0.050 0.000
B95-B98 Bacterial, viral and other infectious agents
0.943 0.057 0.000
G20-G26 Extrapyramidal and movement disorders
0.942 0.058 0.000
S60-S69 Injuries to the wrist and hand
0.942 0.058 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.942 0.058 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.932 0.068 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.932 0.068 0.000
S82 Fracture of lower leg, including ankle
0.927 0.073 0.000
F10.1 Harmful use
0.926 0.074 0.000
I30-I52 Other forms of heart disease
0.919 0.081 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.918 0.082 0.000
F31 Bipolar affective disorder
0.918 0.082 0.000
G20 Parkinson's disease
0.916 0.084 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.912 0.088 0.000
F32 Depressive episode
0.911 0.089 0.000
Chapter XXI Factors influencing health status and contact with health services
0.905 0.095 0.000
E86 Volume depletion
0.901 0.099 0.000
I21 Acute myocardial infarction
0.889 0.111 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.888 0.112 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.887 0.113 0.000
I20.8 Other forms of angina pectoris
0.886 0.114 0.000
E83 Disorders of mineral metabolism
0.884 0.115 0.000
S82.8 Fractures of other parts of lower leg
0.882 0.118 0.000
I60-I69 Cerebrovascular diseases
0.881 0.119 0.000
S00-S09 Injuries to the head
0.873 0.127 0.000
D69 Purpura and other haemorrhagic conditions
0.871 0.129 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.870 0.130 0.000
Chapter XX External causes of morbidity and mortality
0.865 0.135 0.000
C18 Malignant neoplasm of colon
0.864 0.136 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.863 0.137 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.858 0.142 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.857 0.143 0.000
I20.0 Unstable angina
0.853 0.147 0.000
F33 Recurrent depressive disorder
0.853 0.147 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.850 0.150 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.849 0.151 0.000
C15 Malignant neoplasm of oesophagus
0.846 0.154 0.000
I05-I09 Chronic rheumatic heart diseases
0.845 0.155 0.000
I25.1 Atherosclerotic heart disease
0.843 0.157 0.000
D69.6 Thrombocytopenia, unspecified
0.843 0.157 0.000
T66-T78 Other and unspecified effects of external causes
0.835 0.165 0.000
F31.9 Bipolar affective disorder, unspecified
0.828 0.172 0.000
E20-E35 Disorders of other endocrine glands
0.827 0.173 0.000
I22 Subsequent myocardial infarction
0.824 0.176 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.821 0.179 0.000
M20-M25 Other joint disorders
0.821 0.179 0.000
I69 Sequelae of cerebrovascular disease
0.817 0.183 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.817 0.183 0.000
I73 Other peripheral vascular diseases
0.812 0.188 0.000
I95 Hypotension
0.808 0.192 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.807 0.193 0.000
L60-L75 Disorders of skin appendages
0.807 0.193 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.806 0.194 0.000
L20-L30 Dermatitis and eczema
0.806 0.194 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.805 0.195 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.805 0.195 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.804 0.196 0.000
I42 Cardiomyopathy
0.800 0.200 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.799 0.201 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.799 0.201 0.000
S61 Open wound of wrist and hand
0.798 0.202 0.000
C25 Malignant neoplasm of pancreas
0.797 0.203 0.000
I72 Other aneurysm
0.794 0.206 0.000
S60 Superficial injury of wrist and hand
0.794 0.206 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.791 0.208 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
L40-L45 Papulosquamous disorders
0.788 0.212 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.787 0.213 0.000
I70 Atherosclerosis
0.786 0.214 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.786 0.214 0.000
A30-A49 Other bacterial diseases
0.784 0.215 0.000
Z03.4 Observation for suspected myocardial infarction
0.784 0.216 0.000
I63 Cerebral infarction
0.784 0.216 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.783 0.217 0.000
G25 Other extrapyramidal and movement disorders
0.779 0.221 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.778 0.222 0.000
S81 Open wound of lower leg
0.778 0.222 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.777 0.223 0.000
M70-M79 Other soft tissue disorders
0.776 0.224 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.775 0.225 0.000
C51-C58 Malignant neoplasms of female genital organs
0.773 0.227 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.772 0.228 0.000
I46 Cardiac arrest
0.771 0.229 0.000
A00-A09 Intestinal infectious diseases
0.771 0.229 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.771 0.229 0.000
E87.5 Hyperkalaemia
0.771 0.229 0.000
I51 Complications and ill-defined descriptions of heart disease
0.770 0.230 0.000
F32.9 Depressive episode, unspecified
0.770 0.230 0.000
E87.2 Acidosis
0.769 0.231 0.000
M25 Other joint disorders, not elsewhere classified
0.767 0.233 0.000
T79-T79 Certain early complications of trauma
0.767 0.233 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
Z13 Special screening examination for other diseases and disorders
0.766 0.234 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.765 0.235 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.765 0.235 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.763 0.237 0.000
S20-S29 Injuries to the thorax
0.762 0.238 0.000
F10.2 Dependence syndrome
0.760 0.240 0.000
G40-G47 Episodic and paroxysmal disorders
0.759 0.240 0.000
E83.5 Disorders of calcium metabolism
0.758 0.242 0.000
I20.9 Angina pectoris, unspecified
0.758 0.242 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.758 0.242 0.000
S40-S49 Injuries to the shoulder and upper arm
0.757 0.243 0.000
E87.0 Hyperosmolality and hypernatraemia
0.757 0.243 0.000
C15.9 Oesophagus, unspecified
0.756 0.244 0.000
C20 Malignant neoplasm of rectum
0.755 0.245 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.754 0.246 0.000
S06 Intracranial injury
0.749 0.251 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.748 0.252 0.000
I99 Other and unspecified disorders of circulatory system
0.747 0.253 0.000
B35-B49 Mycoses
0.747 0.253 0.000
S89 Other and unspecified injuries of lower leg
0.746 0.254 0.000
D70 Agranulocytosis
0.745 0.255 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.744 0.256 0.000
I73.9 Peripheral vascular disease, unspecified
0.744 0.256 0.000
S70-S79 Injuries to the hip and thigh
0.742 0.258 0.000
S82.2 Fracture of shaft of tibia
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.740 0.260 0.000
D80-D89 Certain disorders involving the immune mechanism
0.738 0.262 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.738 0.262 0.000
I71 Aortic aneurysm and dissection
0.736 0.264 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.736 0.264 0.000
E87.6 Hypokalaemia
0.736 0.264 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.736 0.264 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.735 0.265 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.732 0.268 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.730 0.270 0.000
I49 Other cardiac arrhythmias
0.730 0.270 0.000
V10-V19 Pedal cyclist injured in transport accident
0.729 0.271 0.000
D50-D53 Nutritional anaemias
0.728 0.272 0.000
S82.5 Fracture of medial malleolus
0.727 0.273 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.726 0.274 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.726 0.274 0.000
F10.0 Acute intoxication
0.725 0.275 0.000
D68 Other coagulation defects
0.724 0.275 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.723 0.277 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.722 0.278 0.000
I25.5 Ischaemic cardiomyopathy
0.722 0.278 0.000
L30 Other dermatitis
0.722 0.278 0.000
C16 Malignant neoplasm of stomach
0.721 0.279 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.721 0.279 0.000
C18.5 Splenic flexure
0.720 0.280 0.000
T78 Adverse effects, not elsewhere classified
0.718 0.282 0.000
C18.4 Transverse colon
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M25.5 Pain in joint
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
E83.4 Disorders of magnesium metabolism
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
S02 Fracture of skull and facial bones
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.3 Aneurysm of heart
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.712 0.287 0.000
B02 Zoster [herpes zoster]
0.712 0.288 0.000
F32.1 Moderate depressive episode
0.711 0.288 0.000
E50-E64 Other nutritional deficiencies
0.711 0.289 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.711 0.289 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
D61 Other aplastic anaemias
0.710 0.290 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.710 0.290 0.000
E88 Other metabolic disorders
0.708 0.292 0.000
E85 Amyloidosis
0.708 0.292 0.000
E84 Cystic fibrosis
0.708 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.708 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.708 0.292 0.000
E73 Lactose intolerance
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
B07 Viral warts
0.708 0.292 0.000
F38 Other mood [affective] disorders
0.707 0.293 0.000
F34 Persistent mood [affective] disorders
0.707 0.293 0.000
F30 Manic episode
0.707 0.293 0.000
F39 Unspecified mood [affective] disorder
0.707 0.293 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.707 0.293 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
B15-B19 Viral hepatitis
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
S67 Crushing injury of wrist and hand
0.706 0.294 0.000
I34 Nonrheumatic mitral valve disorders
0.705 0.294 0.000
I51.7 Cardiomegaly
0.705 0.295 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.705 0.295 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.704 0.296 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.703 0.297 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.701 0.299 0.000
D64.8 Other specified anaemias
0.701 0.299 0.000
D64.4 Congenital dyserythropoietic anaemia
0.701 0.299 0.000
D64.3 Other sideroblastic anaemias
0.701 0.299 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.701 0.299 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.701 0.299 0.000
D64.0 Hereditary sideroblastic anaemia
0.701 0.299 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.701 0.299 0.000
L43 Lichen planus
0.701 0.299 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.699 0.301 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.698 0.302 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.698 0.302 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.698 0.302 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.698 0.302 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.698 0.302 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.698 0.302 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.698 0.302 0.000
F11 Mental and behavioural disorders due to use of opioids
0.698 0.302 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.696 0.303 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.696 0.303 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.695 0.305 0.000
E87.4 Mixed disorder of acid-base balance
0.695 0.305 0.000
E87.3 Alkalosis
0.695 0.305 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.695 0.305 0.000
I74 Arterial embolism and thrombosis
0.694 0.306 0.000
M23 Internal derangement of knee
0.693 0.307 0.000
S82.1 Fracture of upper end of tibia
0.693 0.307 0.000
I20.1 Angina pectoris with documented spasm
0.692 0.308 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.308 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.692 0.308 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
S88 Traumatic amputation of lower leg
0.691 0.308 0.000
S87 Crushing injury of lower leg
0.691 0.308 0.000
S86 Injury of muscle and tendon at lower leg level
0.691 0.308 0.000
S85 Injury of blood vessels at lower leg level
0.691 0.308 0.000
S84 Injury of nerves at lower leg level
0.691 0.308 0.000
I47 Paroxysmal tachycardia
0.689 0.311 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.688 0.312 0.000
G62 Other polyneuropathies
0.688 0.312 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.688 0.312 0.000
L50-L54 Urticaria and erythema
0.687 0.312 0.000
I95.9 Hypotension, unspecified
0.687 0.313 0.000
I42.0 Dilated cardiomyopathy
0.687 0.313 0.000
C18.3 Hepatic flexure
0.686 0.314 0.000
I08 Multiple valve diseases
0.685 0.315 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.684 0.316 0.000
Z60 Problems related to social environment
0.684 0.316 0.000
I35 Nonrheumatic aortic valve disorders
0.683 0.317 0.000
F10.9 Unspecified mental and behavioural disorder
0.682 0.318 0.000
F10.8 Other mental and behavioural disorders
0.682 0.318 0.000
F10.7 Residual and late-onset psychotic disorder
0.682 0.318 0.000
F10.6 Amnesic syndrome
0.682 0.318 0.000
F10.5 Psychotic disorder
0.682 0.318 0.000
F10.4 Withdrawal state with delirium
0.682 0.318 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.682 0.318 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.682 0.318 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.682 0.318 0.000
C21 Malignant neoplasm of anus and anal canal
0.682 0.318 0.000
C17 Malignant neoplasm of small intestine
0.682 0.318 0.000
C23 Malignant neoplasm of gallbladder
0.682 0.318 0.000
S68 Traumatic amputation of wrist and hand
0.682 0.318 0.000
I45 Other conduction disorders
0.681 0.319 0.000
D72 Other disorders of white blood cells
0.679 0.321 0.000
E87.7 Fluid overload
0.679 0.321 0.000
M65-M68 Disorders of synovium and tendon
0.679 0.321 0.000
C64-C68 Malignant neoplasms of urinary tract
0.678 0.321 0.000
Z37 Outcome of delivery
0.678 0.322 0.000
L72.0 Epidermal cyst
0.678 0.322 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.678 0.322 0.000
C18.9 Colon, unspecified
0.678 0.322 0.000
F33.9 Recurrent depressive disorder, unspecified
0.677 0.323 0.000
G24 Dystonia
0.676 0.324 0.000
G23 Other degenerative diseases of basal ganglia
0.676 0.324 0.000
G21 Secondary Parkinsonism
0.676 0.324 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.676 0.324 0.000
G22 Parkinsonism in diseases classified elsewhere
0.676 0.324 0.000
S69 Other and unspecified injuries of wrist and hand
0.676 0.324 0.000
S65 Injury of blood vessels at wrist and hand level
0.676 0.324 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.676 0.324 0.000
C34 Malignant neoplasm of bronchus and lung
0.676 0.324 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
M79.8 Other specified soft tissue disorders
0.675 0.325 0.000
I61 Intracerebral haemorrhage
0.675 0.325 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.674 0.326 0.000
C25.0 Head of pancreas
0.674 0.326 0.000
I24 Other acute ischaemic heart diseases
0.673 0.327 0.000
E00-E07 Disorders of thyroid gland
0.673 0.327 0.000
D00-D09 In situ neoplasms
0.673 0.327 0.000
F10.3 Withdrawal state
0.673 0.327 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.673 0.327 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.672 0.328 0.000
S01 Open wound of head
0.672 0.328 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.671 0.329 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.671 0.329 0.000
S82.0 Fracture of patella
0.671 0.329 0.000
F17.2 Dependence syndrome
0.670 0.330 0.000
Z57 Occupational exposure to risk-factors
0.670 0.330 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.669 0.331 0.000
G40 Epilepsy
0.669 0.331 0.000
L10-L14 Bullous disorders
0.668 0.332 0.000
D67 Hereditary factor IX deficiency
0.668 0.332 0.000
D66 Hereditary factor VIII deficiency
0.668 0.332 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.668 0.332 0.000
I95.1 Orthostatic hypotension
0.667 0.333 0.000
E83.1 Disorders of iron metabolism
0.667 0.333 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.666 0.334 0.000
S62 Fracture at wrist and hand level
0.666 0.334 0.000
S82.3 Fracture of lower end of tibia
0.665 0.335 0.000
I62 Other nontraumatic intracranial haemorrhage
0.665 0.335 0.000
S82.9 Fracture of lower leg, part unspecified
0.665 0.335 0.000
S82.7 Multiple fractures of lower leg
0.665 0.335 0.000
S82.4 Fracture of fibula alone
0.665 0.335 0.000
C79 Secondary malignant neoplasm of other sites
0.664 0.336 0.000
I05 Rheumatic mitral valve diseases
0.663 0.337 0.000
S61.8 Open wound of other parts of wrist and hand
0.663 0.337 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.663 0.337 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.663 0.337 0.000
F41 Other anxiety disorders
0.662 0.338 0.000
D62 Acute posthaemorrhagic anaemia
0.662 0.338 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.661 0.338 0.000
L30.9 Dermatitis, unspecified
0.661 0.339 0.000
B25-B34 Other viral diseases
0.660 0.340 0.000
I52 Other heart disorders in diseases classified elsewhere
0.659 0.341 0.000
I48 Atrial fibrillation and flutter
0.659 0.341 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.659 0.341 0.000
I41 Myocarditis in diseases classified elsewhere
0.659 0.341 0.000
I40 Acute myocarditis
0.659 0.341 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.659 0.341 0.000
I37 Pulmonary valve disorders
0.659 0.341 0.000
I36 Nonrheumatic tricuspid valve disorders
0.659 0.341 0.000
I33 Acute and subacute endocarditis
0.659 0.341 0.000
I32 Pericarditis in diseases classified elsewhere
0.659 0.341 0.000
I30 Acute pericarditis
0.659 0.341 0.000
C60-C63 Malignant neoplasms of male genital organs
0.659 0.341 0.000
F31.8 Other bipolar affective disorders
0.658 0.342 0.000
F31.7 Bipolar affective disorder, currently in remission
0.658 0.342 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.658 0.342 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.658 0.342 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.658 0.342 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.658 0.342 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.658 0.342 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.658 0.342 0.000
Y43 Primarily systemic agents
0.658 0.342 0.000
I72.3 Aneurysm of iliac artery
0.657 0.343 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.657 0.343 0.000
M21 Other acquired deformities of limbs
0.655 0.345 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.655 0.345 0.000
V80-V89 Other land transport accidents
0.654 0.346 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.654 0.346 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.654 0.346 0.000
F32.8 Other depressive episodes
0.653 0.347 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.653 0.347 0.000
F32.0 Mild depressive episode
0.653 0.347 0.000
E22 Hyperfunction of pituitary gland
0.652 0.347 0.000
Z35 Supervision of high-risk pregnancy
0.652 0.348 0.000
I77 Other disorders of arteries and arterioles
0.651 0.349 0.000
S50-S59 Injuries to the elbow and forearm
0.650 0.350 0.000
R50-R69 General symptoms and signs
0.650 0.350 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.648 0.352 0.000
V20-V29 Motorcycle rider injured in transport accident
0.647 0.353 0.000
Z03.3 Observation for suspected nervous system disorder
0.647 0.353 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.647 0.353 0.000
G30-G32 Other degenerative diseases of the nervous system
0.646 0.354 0.000
S64 Injury of nerves at wrist and hand level
0.646 0.354 0.000
W00-W19 Falls
0.645 0.355 0.000
M79.6 Pain in limb
0.645 0.355 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.645 0.355 0.000
C15.5 Lower third of oesophagus
0.645 0.355 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.645 0.355 0.000
S81.8 Open wound of other parts of lower leg
0.644 0.356 0.000
C56 Malignant neoplasm of ovary
0.644 0.356 0.000
O85-O92 Complications predominantly related to the puerperium
0.644 0.356 0.000
X60-X84 Intentional self-harm
0.643 0.357 0.000
E23 Hypofunction and other disorders of pituitary gland
0.643 0.357 0.000
S80 Superficial injury of lower leg
0.642 0.358 0.000
M86-M90 Other osteopathies
0.641 0.358 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.638 0.362 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.638 0.362 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.638 0.362 0.000
Z13.9 Special screening examination, unspecified
0.638 0.362 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.637 0.363 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.637 0.363 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.637 0.363 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.637 0.363 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.637 0.363 0.000
M91-M94 Chondropathies
0.636 0.364 0.000
M60-M63 Disorders of muscles
0.636 0.364 0.000
M00-M03 Infectious arthropathies
0.636 0.364 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.635 0.365 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.635 0.365 0.000
O60-O75 Complications of labour and delivery
0.634 0.366 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.634 0.366 0.000
E83.8 Other disorders of mineral metabolism
0.634 0.366 0.000
E83.3 Disorders of phosphorus metabolism
0.634 0.366 0.000
E83.2 Disorders of zinc metabolism
0.634 0.366 0.000
E83.0 Disorders of copper metabolism
0.634 0.366 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.633 0.366 0.000
T78.4 Allergy, unspecified
0.633 0.367 0.000
A41 Other septicaemia
0.633 0.367 0.000
M80-M85 Disorders of bone density and structure
0.633 0.367 0.000
S82.86 Maisonneuve's fracture
0.632 0.368 0.000
S82.81 Fractures of other parts of lower leg (open)
0.632 0.368 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.632 0.368 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.632 0.368 0.000
Y52 Agents primarily affecting the cardiovascular system
0.632 0.368 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.632 0.368 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.632 0.368 0.000
C18.2 Ascending colon
0.631 0.369 0.000
M25.51 Pain in joint (Shoulder region)
0.631 0.369 0.000
E27 Other disorders of adrenal gland
0.630 0.370 0.000
G90-G99 Other disorders of the nervous system
0.628 0.371 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.628 0.372 0.000
I46.9 Cardiac arrest, unspecified
0.628 0.372 0.000
C50-C50 Malignant neoplasm of breast
0.627 0.373 0.000
M23.3 Other meniscus derangements
0.627 0.373 0.000
I07 Rheumatic tricuspid valve diseases
0.627 0.373 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.626 0.374 0.000
S08 Traumatic amputation of part of head
0.626 0.374 0.000
S07 Crushing injury of head
0.626 0.374 0.000
S05 Injury of eye and orbit
0.626 0.374 0.000
S04 Injury of cranial nerves
0.626 0.374 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.626 0.374 0.000
A08 Viral and other specified intestinal infections
0.625 0.375 0.000
S40 Superficial injury of shoulder and upper arm
0.625 0.375 0.000
D69.9 Haemorrhagic condition, unspecified
0.624 0.375 0.000
D69.8 Other specified haemorrhagic conditions
0.624 0.375 0.000
D69.5 Secondary thrombocytopenia
0.624 0.375 0.000
D69.4 Other primary thrombocytopenia
0.624 0.375 0.000
D69.2 Other nonthrombocytopenic purpura
0.624 0.375 0.000
D69.1 Qualitative platelet defects
0.624 0.375 0.000
D69.0 Allergic purpura
0.624 0.375 0.000
A04 Other bacterial intestinal infections
0.624 0.376 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.622 0.378 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.622 0.378 0.000
I72.4 Aneurysm of artery of lower extremity
0.621 0.379 0.000
R47-R49 Symptoms and signs involving speech and voice
0.621 0.379 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.620 0.379 0.000
Y35-Y36 Legal intervention and operations of war
0.620 0.379 0.000
Y10-Y34 Event of undetermined intent
0.620 0.379 0.000
Y00-Y09 Assault
0.620 0.379 0.000
X85-X99 Assault
0.620 0.379 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.620 0.379 0.000
X50-X57 Overexertion, travel and privation
0.620 0.379 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.620 0.379 0.000
X30-X39 Exposure to forces of nature
0.620 0.379 0.000
X20-X29 Contact with venomous animals and plants
0.620 0.379 0.000
X10-X19 Contact with heat and hot substances
0.620 0.379 0.000
X00-X09 Exposure to smoke, fire and flames
0.620 0.379 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.620 0.379 0.000
W75-W84 Other accidental threats to breathing
0.620 0.379 0.000
W65-W74 Accidental drowning and submersion
0.620 0.379 0.000
W50-W64 Exposure to animate mechanical forces
0.620 0.379 0.000
V98-V99 Other and unspecified transport accidents
0.620 0.379 0.000
V95-V97 Air and space transport accidents
0.620 0.379 0.000
V90-V94 Water transport accidents
0.620 0.379 0.000
V70-V79 Bus occupant injured in transport accident
0.620 0.379 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.620 0.379 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.620 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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