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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12067906
log Bayes Factor = 4.52198
Chromosome 1   position 192,431,998  (GRCh37) Explore rs12067906 on Ensembl!
Variant rs12067906 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.986 0.014 0.000
Chapter XI Diseases of the digestive system
0.983 0.017 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.963 0.037 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.957 0.043 0.000
R50-R69 General symptoms and signs
0.949 0.051 0.000
Chapter X Diseases of the respiratory system
0.941 0.059 0.000
R11 Nausea and vomiting
0.902 0.098 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.898 0.102 0.000
R55 Syncope and collapse
0.895 0.105 0.000
Chapter XX External causes of morbidity and mortality
0.891 0.109 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.890 0.110 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.887 0.113 0.000
J40-J47 Chronic lower respiratory diseases
0.880 0.120 0.000
R51 Headache
0.879 0.121 0.000
Chapter IX Diseases of the circulatory system
0.877 0.123 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.874 0.126 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.867 0.133 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.866 0.134 0.000
Chapter XIV Diseases of the genitourinary system
0.840 0.160 0.000
J45 Asthma
0.837 0.162 0.000
R10 Abdominal and pelvic pain
0.836 0.164 0.000
Chapter II Neoplasms
0.834 0.166 0.000
K90-K93 Other diseases of the digestive system
0.822 0.178 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.821 0.179 0.000
K20 Oesophagitis
0.818 0.182 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.808 0.192 0.000
J45.9 Asthma, unspecified
0.807 0.193 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.806 0.194 0.000
Z40 Prophylactic surgery
0.799 0.201 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.799 0.201 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.792 0.208 0.000
Chapter VI Diseases of the nervous system
0.788 0.212 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.787 0.213 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.786 0.214 0.000
K80 Cholelithiasis
0.784 0.216 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.784 0.216 0.000
Z41 Procedures for purposes other than remedying health state
0.777 0.223 0.000
K50-K52 Noninfective enteritis and colitis
0.773 0.227 0.000
Chapter VIII Diseases of the ear and mastoid process
0.771 0.229 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.767 0.233 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.762 0.238 0.000
R12 Heartburn
0.759 0.241 0.000
M50-M54 Other dorsopathies
0.757 0.243 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.755 0.245 0.000
Z47 Other orthopaedic follow-up care
0.754 0.246 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.753 0.247 0.000
Z42 Follow-up care involving plastic surgery
0.753 0.247 0.000
K40-K46 Hernia
0.752 0.248 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.752 0.248 0.000
M70-M79 Other soft tissue disorders
0.750 0.250 0.000
Z50 Care involving use of rehabilitation procedures
0.750 0.250 0.000
R53 Malaise and fatigue
0.749 0.250 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.746 0.254 0.000
Z43 Attention to artificial openings
0.744 0.256 0.000
Chapter VII Diseases of the eye and adnexa
0.742 0.258 0.000
K35-K38 Diseases of appendix
0.742 0.258 0.000
R05 Cough
0.741 0.259 0.000
I10-I15 Hypertensive diseases
0.741 0.259 0.000
J00-J06 Acute upper respiratory infections
0.736 0.264 0.000
Z51 Other medical care
0.727 0.273 0.000
Z13 Special screening examination for other diseases and disorders
0.723 0.277 0.000
J90-J94 Other diseases of pleura
0.721 0.279 0.000
I84 Haemorrhoids
0.719 0.281 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.285 0.000
R47-R49 Symptoms and signs involving speech and voice
0.715 0.285 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.715 0.285 0.000
Chapter V Mental and behavioural disorders
0.715 0.285 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.712 0.288 0.000
R04 Haemorrhage from respiratory passages
0.711 0.289 0.000
J43 Emphysema
0.707 0.293 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.707 0.293 0.000
K70-K77 Diseases of liver
0.705 0.295 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.704 0.296 0.000
R15 Faecal incontinence
0.699 0.301 0.000
R10.4 Other and unspecified abdominal pain
0.699 0.301 0.000
K55-K64 Other diseases of intestines
0.698 0.301 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.698 0.302 0.000
Z53.0 Procedure not carried out because of contraindication
0.697 0.303 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.696 0.304 0.000
R06 Abnormalities of breathing
0.695 0.305 0.000
Z96 Presence of other functional implants
0.692 0.308 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.690 0.309 0.000
R18 Ascites
0.690 0.309 0.000
R17 Unspecified jaundice
0.690 0.309 0.000
R14 Flatulence and related conditions
0.690 0.309 0.000
Chapter I Certain infectious and parasitic diseases
0.689 0.311 0.000
Z54 Convalescence
0.686 0.314 0.000
Z52 Donors of organs and tissues
0.686 0.314 0.000
Z49 Care involving dialysis
0.686 0.314 0.000
Z48 Other surgical follow-up care
0.686 0.314 0.000
Z45 Adjustment and management of implanted device
0.686 0.314 0.000
Z44 Fitting and adjustment of external prosthetic device
0.686 0.314 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.686 0.314 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.686 0.314 0.000
S00-S09 Injuries to the head
0.686 0.314 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.685 0.315 0.000
Z04 Examination and observation for other reasons
0.685 0.315 0.000
K65-K67 Diseases of peritoneum
0.684 0.316 0.000
R07 Pain in throat and chest
0.681 0.319 0.000
J30-J39 Other diseases of upper respiratory tract
0.681 0.319 0.000
J20-J22 Other acute lower respiratory infections
0.681 0.319 0.000
R68 Other general symptoms and signs
0.681 0.319 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.681 0.319 0.000
R62 Lack of expected normal physiological development
0.681 0.319 0.000
R61 Hyperhidrosis
0.681 0.319 0.000
R60 Oedema, not elsewhere classified
0.681 0.319 0.000
R59 Enlarged lymph nodes
0.681 0.319 0.000
R57 Shock, not elsewhere classified
0.681 0.319 0.000
R52 Pain, not elsewhere classified
0.681 0.319 0.000
R64 Cachexia
0.681 0.319 0.000
R58 Haemorrhage, not elsewhere classified
0.681 0.319 0.000
R54 Senility
0.681 0.319 0.000
R56 Convulsions, not elsewhere classified
0.680 0.320 0.000
I80 Phlebitis and thrombophlebitis
0.679 0.321 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.679 0.321 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.677 0.323 0.000
S50-S59 Injuries to the elbow and forearm
0.677 0.323 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.676 0.324 0.000
J95-J99 Other diseases of the respiratory system
0.675 0.325 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.675 0.325 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.675 0.325 0.000
J60-J70 Lung diseases due to external agents
0.675 0.325 0.000
S60-S69 Injuries to the wrist and hand
0.673 0.326 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.673 0.327 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.671 0.329 0.000
O60-O75 Complications of labour and delivery
0.671 0.329 0.000
R10.3 Pain localised to other parts of lower abdomen
0.667 0.333 0.000
R30-R39 Symptoms and signs involving the urinary system
0.665 0.335 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.664 0.336 0.000
Z12 Special screening examination for neoplasms
0.663 0.336 0.000
K44 Diaphragmatic hernia
0.662 0.338 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.662 0.338 0.000
R87 Abnormal findings in specimens from female genital organs
0.657 0.343 0.000
K30 Dyspepsia
0.656 0.344 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
Z46 Fitting and adjustment of other devices
0.655 0.345 0.000
K92 Other diseases of digestive system
0.654 0.346 0.000
I84.6 Residual haemorrhoidal skin tags
0.653 0.347 0.000
K31 Other diseases of stomach and duodenum
0.652 0.348 0.000
M45-M49 Spondylopathies
0.649 0.351 0.000
S80-S89 Injuries to the knee and lower leg
0.648 0.352 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.648 0.352 0.000
N60-N64 Disorders of breast
0.647 0.353 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.645 0.354 0.000
M20-M25 Other joint disorders
0.644 0.356 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.644 0.356 0.000
T79-T79 Certain early complications of trauma
0.644 0.356 0.000
T66-T78 Other and unspecified effects of external causes
0.644 0.356 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.644 0.356 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.644 0.356 0.000
T33-T35 Frostbite
0.644 0.356 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.644 0.356 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.644 0.356 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.644 0.356 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.644 0.356 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.644 0.356 0.000
T00-T07 Injuries involving multiple body regions
0.644 0.356 0.000
S90-S99 Injuries to the ankle and foot
0.644 0.356 0.000
S70-S79 Injuries to the hip and thigh
0.644 0.356 0.000
S40-S49 Injuries to the shoulder and upper arm
0.644 0.356 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.644 0.356 0.000
S20-S29 Injuries to the thorax
0.644 0.356 0.000
S10-S19 Injuries to the neck
0.644 0.356 0.000
C15-C26 Malignant neoplasms of digestive organs
0.644 0.356 0.000
I10 Essential (primary) hypertension
0.643 0.357 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.642 0.358 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.641 0.358 0.000
K25 Gastric ulcer
0.640 0.360 0.000
M05-M14 Inflammatory polyarthropathies
0.639 0.361 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.639 0.361 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.639 0.361 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.639 0.361 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.639 0.361 0.000
Y35-Y36 Legal intervention and operations of war
0.639 0.361 0.000
Y10-Y34 Event of undetermined intent
0.639 0.361 0.000
Y00-Y09 Assault
0.639 0.361 0.000
X85-X99 Assault
0.639 0.361 0.000
X60-X84 Intentional self-harm
0.639 0.361 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.639 0.361 0.000
X50-X57 Overexertion, travel and privation
0.639 0.361 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.639 0.361 0.000
X30-X39 Exposure to forces of nature
0.639 0.361 0.000
X20-X29 Contact with venomous animals and plants
0.639 0.361 0.000
X10-X19 Contact with heat and hot substances
0.639 0.361 0.000
X00-X09 Exposure to smoke, fire and flames
0.639 0.361 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.639 0.361 0.000
W75-W84 Other accidental threats to breathing
0.639 0.361 0.000
W65-W74 Accidental drowning and submersion
0.639 0.361 0.000
W50-W64 Exposure to animate mechanical forces
0.639 0.361 0.000
W20-W49 Exposure to inanimate mechanical forces
0.639 0.361 0.000
V98-V99 Other and unspecified transport accidents
0.639 0.361 0.000
V95-V97 Air and space transport accidents
0.639 0.361 0.000
V90-V94 Water transport accidents
0.639 0.361 0.000
V80-V89 Other land transport accidents
0.639 0.361 0.000
V70-V79 Bus occupant injured in transport accident
0.639 0.361 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.639 0.361 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.639 0.361 0.000
V40-V49 Car occupant injured in transport accident
0.639 0.361 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.639 0.361 0.000
V20-V29 Motorcycle rider injured in transport accident
0.639 0.361 0.000
V10-V19 Pedal cyclist injured in transport accident
0.639 0.361 0.000
V01-V09 Pedestrian injured in transport accident
0.639 0.361 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.638 0.362 0.000
M91-M94 Chondropathies
0.638 0.362 0.000
M86-M90 Other osteopathies
0.638 0.362 0.000
M65-M68 Disorders of synovium and tendon
0.638 0.362 0.000
M60-M63 Disorders of muscles
0.638 0.362 0.000
M40-M43 Deforming dorsopathies
0.638 0.362 0.000
M00-M03 Infectious arthropathies
0.638 0.362 0.000
J47 Bronchiectasis
0.637 0.363 0.000
I30-I52 Other forms of heart disease
0.637 0.363 0.000
Z80 Family history of malignant neoplasm
0.637 0.363 0.000
N10-N16 Renal tubulo-interstitial diseases
0.636 0.364 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.636 0.364 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.636 0.364 0.000
R01 Cardiac murmurs and other cardiac sounds
0.636 0.364 0.000
R02 Gangrene, not elsewhere classified
0.636 0.364 0.000
J09-J18 Influenza and pneumonia
0.635 0.364 0.000
M80-M85 Disorders of bone density and structure
0.634 0.366 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.633 0.367 0.000
H65-H75 Diseases of middle ear and mastoid
0.633 0.367 0.000
J41 Simple and mucopurulent chronic bronchitis
0.631 0.369 0.000
J46 Status asthmaticus
0.631 0.369 0.000
J42 Unspecified chronic bronchitis
0.631 0.369 0.000
J40 Bronchitis, not specified as acute or chronic
0.631 0.369 0.000
Z85 Personal history of malignant neoplasm
0.630 0.370 0.000
I05-I09 Chronic rheumatic heart diseases
0.629 0.371 0.000
I00-I02 Acute rheumatic fever
0.629 0.371 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.628 0.372 0.000
K62 Other diseases of anus and rectum
0.628 0.372 0.000
M54 Dorsalgia
0.627 0.373 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.627 0.373 0.000
Z10 Routine general health check-up of defined subpopulation
0.627 0.373 0.000
Z02 Examination and encounter for administrative purposes
0.627 0.373 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.627 0.373 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.627 0.373 0.000
N17-N19 Renal failure
0.625 0.374 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.625 0.375 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.623 0.377 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.622 0.378 0.000
K86 Other diseases of pancreas
0.622 0.378 0.000
K85 Acute pancreatitis
0.622 0.378 0.000
K83 Other diseases of biliary tract
0.622 0.378 0.000
K82 Other diseases of gallbladder
0.622 0.378 0.000
K81 Cholecystitis
0.622 0.378 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.621 0.378 0.000
K28 Gastrojejunal ulcer
0.621 0.379 0.000
K27 Peptic ulcer, site unspecified
0.621 0.379 0.000
K26 Duodenal ulcer
0.621 0.379 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.621 0.379 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.621 0.379 0.000
I84.1 Internal haemorrhoids with other complications
0.620 0.380 0.000
W00-W19 Falls
0.620 0.380 0.000
R50 Fever of unknown origin
0.619 0.381 0.000
K01 Embedded and impacted teeth
0.618 0.382 0.000
Z90.1 Acquired absence of breast(s)
0.618 0.382 0.000
K50 Crohn's disease [regional enteritis]
0.615 0.385 0.000
C50-C50 Malignant neoplasm of breast
0.615 0.385 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.615 0.385 0.000
R10.1 Pain localised to upper abdomen
0.614 0.386 0.000
E70-E90 Metabolic disorders
0.613 0.387 0.000
Z93 Artificial opening status
0.613 0.387 0.000
M15-M19 Arthrosis
0.609 0.391 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.609 0.391 0.000
G90-G99 Other disorders of the nervous system
0.608 0.392 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.607 0.393 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.607 0.393 0.000
I60-I69 Cerebrovascular diseases
0.606 0.394 0.000
Z96.6 Presence of orthopaedic joint implants
0.605 0.395 0.000
T81 Complications of procedures, not elsewhere classified
0.603 0.397 0.000
N99-N99 Other disorders of the genitourinary system
0.602 0.398 0.000
N25-N29 Other disorders of kidney and ureter
0.602 0.398 0.000
N00-N08 Glomerular diseases
0.602 0.398 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.601 0.398 0.000
J45.8 Mixed asthma
0.600 0.399 0.000
J45.1 Nonallergic asthma
0.600 0.399 0.000
J45.0 Predominantly allergic asthma
0.600 0.399 0.000
R07.2 Precordial pain
0.600 0.400 0.000
M51 Other intervertebral disk disorders
0.599 0.401 0.000
R10.2 Pelvic and perineal pain
0.599 0.401 0.000
R10.0 Acute abdomen
0.599 0.401 0.000
K13 Other diseases of lip and oral mucosa
0.599 0.401 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.599 0.401 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.598 0.402 0.000
D00-D09 In situ neoplasms
0.598 0.402 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.598 0.402 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.598 0.402 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.598 0.402 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.598 0.402 0.000
C64-C68 Malignant neoplasms of urinary tract
0.598 0.402 0.000
C51-C58 Malignant neoplasms of female genital organs
0.598 0.402 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.598 0.402 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.598 0.402 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.598 0.402 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.598 0.402 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.597 0.402 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.597 0.403 0.000
K22 Other diseases of oesophagus
0.597 0.403 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.594 0.406 0.000
K21 Gastro-oesophageal reflux disease
0.594 0.406 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.592 0.408 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.591 0.409 0.000
Z43.2 Attention to ileostomy
0.590 0.409 0.000
J02 Acute pharyngitis
0.589 0.410 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.589 0.411 0.000
K90 Intestinal malabsorption
0.589 0.411 0.000
N20-N23 Urolithiasis
0.589 0.411 0.000
M72 Fibroblastic disorders
0.589 0.411 0.000
Y83.8 Other surgical procedures
0.588 0.412 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.588 0.412 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.587 0.413 0.000
R04.0 Epistaxis
0.587 0.413 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.586 0.413 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.585 0.414 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.585 0.415 0.000
N72 Inflammatory disease of cervix uteri
0.584 0.416 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.584 0.416 0.000
J43.9 Emphysema, unspecified
0.584 0.416 0.000
L60-L75 Disorders of skin appendages
0.582 0.418 0.000
Z51.2 Other chemotherapy
0.581 0.419 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.579 0.420 0.000
O85-O92 Complications predominantly related to the puerperium
0.579 0.420 0.000
O80-O84 Delivery
0.579 0.420 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.579 0.420 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.579 0.420 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.579 0.420 0.000
O00-O08 Pregnancy with abortive outcome
0.579 0.420 0.000
M75 Shoulder lesions
0.579 0.421 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.578 0.422 0.000
I88 Nonspecific lymphadenitis
0.578 0.422 0.000
I87 Other disorders of veins
0.578 0.422 0.000
I86 Varicose veins of other sites
0.578 0.422 0.000
I85 Oesophageal varices
0.578 0.422 0.000
I82 Other venous embolism and thrombosis
0.578 0.422 0.000
I81 Portal vein thrombosis
0.578 0.422 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.578 0.422 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.577 0.423 0.000
R00 Abnormalities of heart beat
0.575 0.425 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.574 0.426 0.000
Z40.9 Prophylactic surgery, unspecified
0.573 0.427 0.000
Z40.8 Other prophylactic surgery
0.573 0.427 0.000
H53-H54 Visual disturbances and blindness
0.573 0.427 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.573 0.427 0.000
R86 Abnormal findings in specimens from male genital organs
0.573 0.427 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.573 0.427 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.573 0.427 0.000
R83 Abnormal findings in cerebrospinal fluid
0.573 0.427 0.000
D10-D36 Benign neoplasms
0.570 0.429 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.569 0.431 0.000
K35 Acute appendicitis
0.569 0.431 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.569 0.431 0.000
K51 Ulcerative colitis
0.568 0.432 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.567 0.432 0.000
C60-C63 Malignant neoplasms of male genital organs
0.567 0.432 0.000
I83 Varicose veins of lower extremities
0.566 0.433 0.000
R21 Rash and other nonspecific skin eruption
0.566 0.434 0.000
G70-G73 Diseases of myoneural junction and muscle
0.565 0.435 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.565 0.435 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.565 0.435 0.000
G30-G32 Other degenerative diseases of the nervous system
0.565 0.435 0.000
G20-G26 Extrapyramidal and movement disorders
0.565 0.435 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.565 0.435 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.565 0.435 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.565 0.435 0.000
Z98 Other postsurgical states
0.565 0.435 0.000
Z97 Presence of other devices
0.565 0.435 0.000
Z94 Transplanted organ and tissue status
0.565 0.435 0.000
Z89 Acquired absence of limb
0.565 0.435 0.000
Z84 Family history of other conditions
0.565 0.435 0.000
Z83 Family history of other specific disorders
0.565 0.435 0.000
Z81 Family history of mental and behavioural disorders
0.565 0.435 0.000
K14 Diseases of tongue
0.564 0.436 0.000
K12 Stomatitis and related lesions
0.564 0.436 0.000
K11 Diseases of salivary glands
0.564 0.436 0.000
K10 Other diseases of jaws
0.564 0.436 0.000
K09 Cysts of oral region, not elsewhere classified
0.564 0.436 0.000
K08 Other disorders of teeth and supporting structures
0.564 0.436 0.000
K07 Dentofacial anomalies [including malocclusion]
0.564 0.436 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.564 0.436 0.000
K05 Gingivitis and periodontal diseases
0.564 0.436 0.000
K04 Diseases of pulp and periapical tissues
0.564 0.436 0.000
K03 Other diseases of hard tissues of teeth
0.564 0.436 0.000
K02 Dental caries
0.564 0.436 0.000
K00 Disorders of tooth development and eruption
0.564 0.436 0.000
J90 Pleural effusion, not elsewhere classified
0.563 0.437 0.000
I84.2 Internal haemorrhoids without complication
0.563 0.437 0.000
K80.3 Calculus of bile duct with cholangitis
0.562 0.438 0.000
K80.8 Other cholelithiasis
0.562 0.438 0.000
K80.4 Calculus of bile duct with cholecystitis
0.562 0.438 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.562 0.438 0.000
T87 Complications peculiar to reattachment and amputation
0.562 0.438 0.000
T86 Failure and rejection of transplanted organs and tissues
0.562 0.438 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.562 0.438 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.562 0.438 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.562 0.438 0.000
R19.4 Change in bowel habit
0.561 0.439 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.560 0.440 0.000
O70 Perineal laceration during delivery
0.560 0.440 0.000
L20-L30 Dermatitis and eczema
0.559 0.441 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.557 0.442 0.000
N92 Excessive, frequent and irregular menstruation
0.557 0.443 0.000
Z51.3 Blood transfusion without reported diagnosis
0.557 0.443 0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified
0.557 0.443 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.557 0.443 0.000
Z41.3 Ear piercing
0.557 0.443 0.000
Z41.2 Routine and ritual circumcision
0.557 0.443 0.000
Z41.0 Hair transplant
0.557 0.443 0.000
R87.6 Abnormal cytological findings
0.554 0.445 0.000
R32 Unspecified urinary incontinence
0.554 0.446 0.000
Z53.9 Procedure not carried out, unspecified reason
0.554 0.446 0.000
K62.5 Haemorrhage of anus and rectum
0.553 0.447 0.000
H80-H83 Diseases of inner ear
0.553 0.447 0.000
H60-H62 Diseases of external ear
0.553 0.447 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.553 0.447 0.000
N88 Other noninflammatory disorders of cervix uteri
0.552 0.448 0.000
Y83.6 Removal of other organ (partial) (total)
0.552 0.448 0.000
L40-L45 Papulosquamous disorders
0.552 0.448 0.000
K58 Irritable bowel syndrome
0.550 0.450 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.550 0.450 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.550 0.450 0.000
Z04.8 Examination and observation for other specified reasons
0.549 0.451 0.000
K52 Other non-infective gastro-enteritis and colitis
0.549 0.451 0.000
Z13.9 Special screening examination, unspecified
0.549 0.451 0.000
E00-E07 Disorders of thyroid gland
0.548 0.452 0.000
K91.4 Colostomy and enterostomy malfunction
0.547 0.453 0.000
L50-L54 Urticaria and erythema
0.546 0.453 0.000
L10-L14 Bullous disorders
0.546 0.453 0.000
K62.8 Other specified diseases of anus and rectum
0.546 0.454 0.000
H40-H42 Glaucoma
0.544 0.456 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.543 0.457 0.000
M53 Other dorsopathies, not elsewhere classified
0.543 0.457 0.000
M50 Cervical disk disorders
0.543 0.457 0.000
R94 Abnormal results of function studies
0.543 0.457 0.000
N84 Polyp of female genital tract
0.543 0.457 0.000
Z50.1 Other physical therapy
0.542 0.457 0.000
E50-E64 Other nutritional deficiencies
0.541 0.459 0.000
E40-E46 Malnutrition
0.541 0.459 0.000
E20-E35 Disorders of other endocrine glands
0.541 0.459 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.541 0.459 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.541 0.459 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.541 0.459 0.000
Z47.8 Other specified orthopaedic follow-up care
0.541 0.459 0.000
R19.6 Halitosis
0.540 0.460 0.000
R19.5 Other fecal abnormalities
0.540 0.460 0.000
R19.3 Abdominal rigidity
0.540 0.460 0.000
R19.2 Visible peristalsis
0.540 0.460 0.000
R19.1 Abnormal bowel sounds
0.540 0.460 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.540 0.460 0.000
Z96.1 Presence of intraocular lens
0.540 0.460 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.540 0.460 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.540 0.460 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.540 0.460 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.540 0.460 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.540 0.460 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.540 0.460 0.000
H30-H36 Disorders of choroid and retina
0.540 0.460 0.000
K46 Unspecified abdominal hernia
0.539 0.461 0.000
K45 Other abdominal hernia
0.539 0.461 0.000
K41 Femoral hernia
0.539 0.461 0.000
Y83.9 Surgical procedure, unspecified
0.539 0.461 0.000
Y83.5 Amputation of limb(s)
0.539 0.461 0.000
Y83.4 Other reconstructive surgery
0.539 0.461 0.000
Y83.3 Surgical operation with formation of external stoma
0.539 0.461 0.000
Y83.0 Surgical operation with transplant of whole organ
0.539 0.461 0.000
R13 Dysphagia
0.538 0.462 0.000
E65-E68 Obesity and other hyperalimentation
0.538 0.462 0.000
M77 Other enthesopathies
0.538 0.462 0.000
M76 Enthesopathies of lower limb, excluding foot
0.538 0.462 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.538 0.462 0.000
M71 Other bursopathies
0.538 0.462 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.538 0.462 0.000
Z50.8 Care involving use of rehabilitation procedures
0.538 0.462 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.538 0.462 0.000
Z50.6 Orthoptic training
0.538 0.462 0.000
Z50.5 Speech therapy
0.538 0.462 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.538 0.462 0.000
Z50.3 Drug rehabilitation
0.538 0.462 0.000
Z50.2 Alcohol rehabilitation
0.538 0.462 0.000
Z50.0 Cardiac rehabilitation
0.538 0.462 0.000
Y84.8 Other medical procedures
0.535 0.465 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.535 0.465 0.000
R23 Other skin changes
0.535 0.465 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.535 0.465 0.000
R20 Disturbances of skin sensation
0.535 0.465 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.534 0.466 0.000
S01 Open wound of head
0.534 0.466 0.000
Z43.9 Attention to unspecified artificial opening
0.533 0.467 0.000
Z43.8 Attention to other artificial openings
0.533 0.467 0.000
Z43.7 Attention to artificial vagina
0.533 0.467 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.533 0.467 0.000
Z43.5 Attention to cyctostomy
0.533 0.467 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.533 0.467 0.000
Z43.3 Attention to colostomy
0.533 0.467 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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