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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12186945
log Bayes Factor = 13.9379
Chromosome 5   position 124,600,310  (GRCh37) Explore rs12186945 on Ensembl!
Variant rs12186945 is listed in the   GWAS Catalog   ⇪
Variant rs12186945 is part of Cluster X0140

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
M17 Gonarthrosis [arthrosis of knee]
0.998 0.002 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
T81 Complications of procedures, not elsewhere classified
0.996 0.004 0.000
B95-B98 Bacterial, viral and other infectious agents
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.995 0.005 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
Chapter II Neoplasms
0.993 0.007 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.992 0.008 0.000
M47 Spondylosis
0.992 0.008 0.000
C15-C26 Malignant neoplasms of digestive organs
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.985 0.015 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.982 0.018 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.976 0.024 0.000
M17.9 Gonarthrosis, unspecified
0.976 0.024 0.000
M25 Other joint disorders, not elsewhere classified
0.975 0.025 0.000
Chapter IX Diseases of the circulatory system
0.972 0.028 0.000
M23 Internal derangement of knee
0.969 0.031 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.962 0.038 0.000
C18 Malignant neoplasm of colon
0.961 0.039 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.956 0.044 0.000
M05-M14 Inflammatory polyarthropathies
0.952 0.048 0.000
W00-W19 Falls
0.943 0.057 0.000
S40-S49 Injuries to the shoulder and upper arm
0.942 0.058 0.000
M17.1 Other primary gonarthrosis
0.942 0.058 0.000
M25.7 Osteophyte
0.931 0.069 0.000
E20-E35 Disorders of other endocrine glands
0.931 0.069 0.000
I05-I09 Chronic rheumatic heart diseases
0.929 0.071 0.000
M65-M68 Disorders of synovium and tendon
0.918 0.082 0.000
M47.2 Other spondylosis with radiculopathy
0.918 0.082 0.000
M10 Gout
0.917 0.083 0.000
E86 Volume depletion
0.916 0.084 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.914 0.086 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.913 0.087 0.000
M23.3 Other meniscus derangements
0.907 0.093 0.000
E87.2 Acidosis
0.907 0.093 0.000
E87.6 Hypokalaemia
0.903 0.097 0.000
M48 Other spondylopathies
0.903 0.097 0.000
M47.8 Other spondylosis
0.903 0.097 0.000
E50-E64 Other nutritional deficiencies
0.902 0.098 0.000
C18.2 Ascending colon
0.901 0.099 0.000
E87.7 Fluid overload
0.898 0.102 0.000
M25.5 Pain in joint
0.896 0.104 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.896 0.104 0.000
M47.9 Spondylosis, unspecified
0.894 0.106 0.000
I60-I69 Cerebrovascular diseases
0.894 0.106 0.000
M10.9 Gout, unspecified
0.893 0.107 0.000
M70-M79 Other soft tissue disorders
0.888 0.112 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.887 0.113 0.000
A30-A49 Other bacterial diseases
0.880 0.120 0.000
M10.99 Gout, unspecified (Site unspecified)
0.879 0.121 0.000
C18.9 Colon, unspecified
0.878 0.122 0.000
C20 Malignant neoplasm of rectum
0.871 0.129 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.864 0.136 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.861 0.139 0.000
C64-C68 Malignant neoplasms of urinary tract
0.860 0.140 0.000
I05 Rheumatic mitral valve diseases
0.857 0.143 0.000
M65 Synovitis and tenosynovitis
0.857 0.143 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.855 0.145 0.000
M18 Arthrosis of first carpometacarpal joint
0.853 0.147 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.852 0.148 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.850 0.150 0.000
Chapter VIII Diseases of the ear and mastoid process
0.849 0.151 0.000
M24 Other specific joint derangements
0.849 0.151 0.000
M40-M43 Deforming dorsopathies
0.848 0.152 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.848 0.152 0.000
M47.1 Other spondylosis with myelopathy
0.847 0.153 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.846 0.154 0.000
W07 Fall involving chair
0.845 0.155 0.000
M17.5 Other secondary gonarthrosis
0.842 0.157 0.000
W18 Other fall on same level
0.835 0.165 0.000
I30-I52 Other forms of heart disease
0.834 0.166 0.000
C21 Malignant neoplasm of anus and anal canal
0.833 0.167 0.000
M25.77 Osteophyte (Ankle and foot)
0.833 0.167 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.831 0.169 0.000
E88 Other metabolic disorders
0.831 0.169 0.000
E87.3 Alkalosis
0.830 0.170 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.830 0.170 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.829 0.171 0.000
M17.3 Other posttraumatic gonarthrosis
0.828 0.172 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.827 0.173 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.827 0.173 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.826 0.174 0.000
Y40 Systemic antibiotics
0.826 0.174 0.000
E22 Hyperfunction of pituitary gland
0.825 0.175 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.821 0.179 0.000
B99-B99 Other infectious diseases
0.820 0.180 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.815 0.185 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.815 0.185 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.814 0.186 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.814 0.186 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.814 0.186 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.813 0.187 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.813 0.187 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.812 0.188 0.000
Chapter XXI Factors influencing health status and contact with health services
0.811 0.189 0.000
M25.76 Osteophyte (Lower leg)
0.809 0.191 0.000
I60 Subarachnoid haemorrhage
0.809 0.191 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.809 0.191 0.000
S43.0 Dislocation of shoulder joint
0.808 0.192 0.000
M19 Other arthrosis
0.806 0.194 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.805 0.195 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.805 0.195 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.801 0.199 0.000
M17.0 Primary gonarthrosis, bilateral
0.801 0.199 0.000
B50-B64 Protozoal diseases
0.800 0.200 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.798 0.202 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.798 0.202 0.000
M25.51 Pain in joint (Shoulder region)
0.798 0.202 0.000
C67 Malignant neoplasm of bladder
0.797 0.203 0.000
E27 Other disorders of adrenal gland
0.797 0.203 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.797 0.203 0.000
M46 Other inflammatory spondylopathies
0.796 0.204 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.796 0.204 0.000
C18.6 Descending colon
0.795 0.204 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.795 0.205 0.000
M06 Other rheumatoid arthritis
0.792 0.208 0.000
S42 Fracture of shoulder and upper arm
0.791 0.209 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.790 0.210 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.790 0.210 0.000
E61 Deficiency of other nutrient elements
0.790 0.210 0.000
S20-S29 Injuries to the thorax
0.790 0.210 0.000
W07.9 Unspecified place
0.790 0.210 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.789 0.211 0.000
S90-S99 Injuries to the ankle and foot
0.789 0.211 0.000
T86 Failure and rejection of transplanted organs and tissues
0.786 0.214 0.000
H65-H75 Diseases of middle ear and mastoid
0.785 0.215 0.000
M23.8 Other internal derangements of knee
0.781 0.219 0.000
M48.0 Spinal stenosis
0.781 0.219 0.000
S70-S79 Injuries to the hip and thigh
0.780 0.220 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.780 0.220 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.779 0.221 0.000
C16 Malignant neoplasm of stomach
0.778 0.221 0.000
I35 Nonrheumatic aortic valve disorders
0.777 0.223 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.777 0.223 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.777 0.223 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.777 0.223 0.000
B15-B19 Viral hepatitis
0.777 0.223 0.000
M21 Other acquired deformities of limbs
0.775 0.225 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.774 0.226 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.773 0.227 0.000
Chapter VI Diseases of the nervous system
0.772 0.228 0.000
M25.53 Pain in joint (Forearm)
0.772 0.228 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.770 0.230 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.770 0.230 0.000
M25.52 Pain in joint (Upper arm)
0.770 0.230 0.000
Chapter X Diseases of the respiratory system
0.770 0.230 0.000
E23 Hypofunction and other disorders of pituitary gland
0.769 0.231 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.769 0.231 0.000
Z43 Attention to artificial openings
0.767 0.232 0.000
M79.6 Pain in limb
0.766 0.234 0.000
C51-C58 Malignant neoplasms of female genital organs
0.766 0.234 0.000
M15 Polyarthrosis
0.765 0.234 0.000
W20-W49 Exposure to inanimate mechanical forces
0.765 0.235 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.764 0.236 0.000
W10 Fall on and from stairs and steps
0.764 0.236 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.764 0.236 0.000
T87 Complications peculiar to reattachment and amputation
0.762 0.237 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.761 0.239 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.761 0.239 0.000
C18.4 Transverse colon
0.760 0.240 0.000
T66-T78 Other and unspecified effects of external causes
0.759 0.240 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.759 0.241 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.759 0.241 0.000
I08 Multiple valve diseases
0.759 0.241 0.000
I07 Rheumatic tricuspid valve diseases
0.757 0.243 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.756 0.244 0.000
E53 Deficiency of other B group vitamins
0.756 0.244 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.755 0.244 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.754 0.246 0.000
E87.5 Hyperkalaemia
0.754 0.246 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.754 0.246 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.753 0.247 0.000
M47.89 Other spondylosis (Site unspecified)
0.752 0.248 0.000
M25.8 Other specified joint disorders
0.752 0.248 0.000
B35-B49 Mycoses
0.750 0.249 0.000
Z51 Other medical care
0.750 0.250 0.000
C17 Malignant neoplasm of small intestine
0.749 0.251 0.000
X20-X29 Contact with venomous animals and plants
0.748 0.251 0.000
J09-J18 Influenza and pneumonia
0.748 0.252 0.000
T00-T07 Injuries involving multiple body regions
0.747 0.253 0.000
V80-V89 Other land transport accidents
0.746 0.254 0.000
I34 Nonrheumatic mitral valve disorders
0.746 0.254 0.000
E85 Amyloidosis
0.746 0.254 0.000
V40-V49 Car occupant injured in transport accident
0.746 0.254 0.000
S41 Open wound of shoulder and upper arm
0.746 0.254 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.745 0.255 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.745 0.255 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.743 0.257 0.000
S60-S69 Injuries to the wrist and hand
0.742 0.258 0.000
W18.5 Trade and service area
0.741 0.259 0.000
M25.50 Pain in joint (Multiple sites)
0.741 0.259 0.000
C73 Malignant neoplasm of thyroid gland
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.738 0.262 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.738 0.262 0.000
I35.0 Aortic (valve) stenosis
0.737 0.263 0.000
S10-S19 Injuries to the neck
0.736 0.264 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.735 0.265 0.000
Z51.0 Radiotherapy session
0.734 0.266 0.000
Z43.2 Attention to ileostomy
0.733 0.267 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.730 0.269 0.000
M43 Other deforming dorsopathies
0.730 0.270 0.000
A40 Streptococcal septicaemia
0.730 0.270 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.729 0.271 0.000
M91-M94 Chondropathies
0.728 0.272 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.727 0.273 0.000
I31 Other diseases of pericardium
0.726 0.274 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.724 0.275 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.724 0.276 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.723 0.277 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.723 0.277 0.000
G90-G99 Other disorders of the nervous system
0.723 0.277 0.000
I05.9 Mitral valve disease, unspecified
0.722 0.278 0.000
H65 Nonsuppurative otitis media
0.721 0.279 0.000
D46 Myelodysplastic syndromes
0.720 0.280 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.719 0.281 0.000
M25.74 Osteophyte (Hand)
0.718 0.282 0.000
M16 Coxarthrosis [arthrosis of hip]
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
M79.1 Myalgia
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.715 0.284 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.715 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.285 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.715 0.285 0.000
M22 Disorders of patella
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
I80 Phlebitis and thrombophlebitis
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
J18 Pneumonia, organism unspecified
0.714 0.286 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.714 0.286 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.714 0.286 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.714 0.286 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.714 0.286 0.000
A41 Other septicaemia
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.713 0.287 0.000
E73 Lactose intolerance
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
E87.4 Mixed disorder of acid-base balance
0.711 0.288 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.711 0.289 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.710 0.289 0.000
C23 Malignant neoplasm of gallbladder
0.710 0.289 0.000
E24 Cushing's syndrome
0.710 0.289 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.710 0.290 0.000
M25.54 Pain in joint (Hand)
0.710 0.290 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.710 0.290 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.710 0.290 0.000
E61.1 Iron deficiency
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.290 0.000
Y10-Y34 Event of undetermined intent
0.709 0.290 0.000
Y00-Y09 Assault
0.709 0.290 0.000
X85-X99 Assault
0.709 0.290 0.000
X50-X57 Overexertion, travel and privation
0.709 0.290 0.000
X30-X39 Exposure to forces of nature
0.709 0.290 0.000
X10-X19 Contact with heat and hot substances
0.709 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.290 0.000
W75-W84 Other accidental threats to breathing
0.709 0.290 0.000
W65-W74 Accidental drowning and submersion
0.709 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.290 0.000
V95-V97 Air and space transport accidents
0.709 0.290 0.000
V90-V94 Water transport accidents
0.709 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.292 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.706 0.294 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.706 0.294 0.000
M34 Systemic sclerosis
0.705 0.295 0.000
T82.1 Mechanical complication of cardiac electronic device
0.704 0.295 0.000
S30.0 Contusion of lower back and pelvis
0.703 0.297 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.702 0.298 0.000
Z42 Follow-up care involving plastic surgery
0.702 0.298 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.702 0.298 0.000
E40-E46 Malnutrition
0.702 0.298 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.702 0.298 0.000
M86-M90 Other osteopathies
0.701 0.298 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.701 0.299 0.000
C18.1 Appendix
0.700 0.300 0.000
C18.7 Sigmoid colon
0.700 0.300 0.000
M25.3 Other instability of joint
0.699 0.301 0.000
M25.2 Flail joint
0.699 0.301 0.000
M25.1 Fistula of joint
0.699 0.301 0.000
M25.0 Haemarthrosis
0.699 0.301 0.000
I05.2 Mitral stenosis with insufficiency
0.699 0.301 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.698 0.302 0.000
Z41 Procedures for purposes other than remedying health state
0.697 0.303 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.697 0.303 0.000
I00-I02 Acute rheumatic fever
0.697 0.303 0.000
C25 Malignant neoplasm of pancreas
0.697 0.303 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.696 0.304 0.000
Z53.8 Procedure not carried out for other reasons
0.696 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.696 0.304 0.000
Y40.8 Other systemic antibiotics
0.695 0.305 0.000
M23.9 Internal derangement of knee, unspecified
0.695 0.305 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.695 0.305 0.000
M23.1 Discoid meniscus (congenital)
0.695 0.305 0.000
M23.0 Cystic meniscus
0.695 0.305 0.000
C21.1 Anal canal
0.694 0.306 0.000
I61 Intracerebral haemorrhage
0.692 0.308 0.000
Y40.9 Systemic antibiotic, unspecified
0.692 0.308 0.000
B99 Other and unspecified infectious diseases
0.691 0.308 0.000
M24.1 Other articular cartilage disorders
0.691 0.309 0.000
E28 Ovarian dysfunction
0.691 0.309 0.000
M31 Other necrotising vasculopathies
0.691 0.309 0.000
T79-T79 Certain early complications of trauma
0.690 0.310 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.690 0.310 0.000
C18.8 Overlapping lesion of colon
0.689 0.311 0.000
C67.6 Ureteric orifice
0.689 0.311 0.000
M66 Spontaneous rupture of synovium and tendon
0.689 0.311 0.000
S90 Superficial injury of ankle and foot
0.688 0.312 0.000
C26.0 Intestinal tract, part unspecified
0.688 0.312 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.687 0.313 0.000
I37 Pulmonary valve disorders
0.687 0.313 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.687 0.313 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.686 0.314 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.686 0.314 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.686 0.314 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.685 0.315 0.000
D00-D09 In situ neoplasms
0.684 0.316 0.000
M45 Ankylosing spondylitis
0.684 0.316 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.684 0.316 0.000
H71 Cholesteatoma of middle ear
0.684 0.316 0.000
C67.2 Lateral wall of bladder
0.683 0.317 0.000
I05.0 Mitral stenosis
0.683 0.317 0.000
M14 Arthropathies in other diseases classified elsewhere
0.682 0.318 0.000
M12 Other specific arthropathies
0.682 0.318 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.682 0.318 0.000
M08 Juvenile arthritis
0.682 0.318 0.000
J18.0 Bronchopneumonia, unspecified
0.682 0.318 0.000
M25.9 Joint disorder, unspecified
0.682 0.318 0.000
I34.0 Mitral (valve) insufficiency
0.681 0.319 0.000
I81 Portal vein thrombosis
0.681 0.319 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.681 0.319 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.320 0.000
I63 Cerebral infarction
0.680 0.320 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.680 0.320 0.000
S01 Open wound of head
0.679 0.321 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.678 0.321 0.000
W19 Unspecified fall
0.678 0.322 0.000
H60-H62 Diseases of external ear
0.678 0.322 0.000
M79.0 Rheumatism, unspecified
0.677 0.323 0.000
M11 Other crystal arthropathies
0.676 0.324 0.000
E22.1 Hyperprolactinaemia
0.676 0.324 0.000
W17 Other fall from one level to another
0.676 0.324 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.676 0.324 0.000
W15 Fall from cliff
0.676 0.324 0.000
W14 Fall from tree
0.676 0.324 0.000
W12 Fall on and from scaffolding
0.676 0.324 0.000
W11 Fall on and from ladder
0.676 0.324 0.000
W09 Fall involving playground equipment
0.676 0.324 0.000
W05 Fall involving wheelchair
0.676 0.324 0.000
W04 Fall while being carried or supported by other persons
0.676 0.324 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.676 0.324 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.676 0.324 0.000
W00 Fall on same level involving ice and snow
0.676 0.324 0.000
S48 Traumatic amputation of shoulder and upper arm
0.676 0.324 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.676 0.324 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.676 0.324 0.000
S44 Injury of nerves at shoulder and upper arm level
0.676 0.324 0.000
S47 Crushing injury of shoulder and upper arm
0.676 0.324 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.675 0.325 0.000
M07 Psoriatic and enteropathic arthropathies
0.675 0.325 0.000
M77 Other enthesopathies
0.675 0.325 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.675 0.325 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.674 0.326 0.000
X60-X84 Intentional self-harm
0.673 0.327 0.000
Z45 Adjustment and management of implanted device
0.672 0.328 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.670 0.330 0.000
M79.9 Soft tissue disorder, unspecified
0.670 0.330 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.669 0.330 0.000
C71 Malignant neoplasm of brain
0.669 0.331 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.668 0.332 0.000
J40-J47 Chronic lower respiratory diseases
0.668 0.332 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.668 0.332 0.000
M25.79 Osteophyte (Site unspecified)
0.667 0.333 0.000
M25.73 Osteophyte (Forearm)
0.667 0.333 0.000
M25.72 Osteophyte (Upper arm)
0.667 0.333 0.000
M25.71 Osteophyte (Shoulder region)
0.667 0.333 0.000
M25.70 Osteophyte (Multiple sites)
0.667 0.333 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.667 0.333 0.000
E34 Other endocrine disorders
0.667 0.333 0.000
E32 Diseases of thymus
0.667 0.333 0.000
E31 Polyglandular dysfunction
0.667 0.333 0.000
E30 Disorders of puberty, not elsewhere classified
0.667 0.333 0.000
E26 Hyperaldosteronism
0.667 0.333 0.000
E25 Adrenogenital disorders
0.667 0.333 0.000
E20 Hypoparathyroidism
0.667 0.333 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.667 0.333 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.667 0.333 0.000
I09 Other rheumatic heart diseases
0.666 0.334 0.000
I06 Rheumatic aortic valve diseases
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.666 0.334 0.000
S32 Fracture of lumbar spine and pelvis
0.666 0.334 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.666 0.334 0.000
Y44 Agents primarily affecting blood constituents
0.665 0.335 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.664 0.336 0.000
C34 Malignant neoplasm of bronchus and lung
0.664 0.336 0.000
I05.1 Rheumatic mitral insufficiency
0.662 0.338 0.000
I62 Other nontraumatic intracranial haemorrhage
0.662 0.338 0.000
M79.8 Other specified soft tissue disorders
0.662 0.338 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.661 0.339 0.000
S42.0 Fracture of clavicle
0.660 0.340 0.000
T81.9 Unspecified complication of procedure
0.659 0.340 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.659 0.341 0.000
M79.5 Residual foreign body in soft tissue
0.658 0.341 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.658 0.342 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.658 0.342 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.658 0.342 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.658 0.342 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.658 0.342 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.658 0.342 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.658 0.342 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.658 0.342 0.000
A49 Bacterial infection of unspecified site
0.658 0.342 0.000
M10.4 Other secondary gout
0.658 0.342 0.000
M10.3 Gout due to impairment of renal function
0.658 0.342 0.000
M10.2 Drug-induced gout
0.658 0.342 0.000
M10.1 Lead-induced gout
0.658 0.342 0.000
M10.0 Idiopathic gout
0.658 0.342 0.000
T90 Sequelae of injuries of head
0.658 0.342 0.000
B59 Pneumocystosis
0.657 0.342 0.000
G90 Disorders of autonomic nervous system
0.656 0.344 0.000
M47.86 Other spondylosis (Lumbar region)
0.656 0.344 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.656 0.344 0.000
C32 Malignant neoplasm of larynx
0.656 0.344 0.000
Y59 Other and unspecified vaccines and biological substances
0.655 0.345 0.000
Y58 Bacterial vaccines
0.655 0.345 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.655 0.345 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.655 0.345 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.655 0.345 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.655 0.345 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.655 0.345 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.655 0.345 0.000
Y48 Anaesthetics and therapeutic gases
0.655 0.345 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.655 0.345 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.655 0.345 0.000
M50-M54 Other dorsopathies
0.655 0.345 0.000
H74 Other disorders of middle ear and mastoid
0.655 0.345 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.655 0.345 0.000
S37 Injury of urinary and pelvic organs
0.655 0.345 0.000
S36 Injury of intra-abdominal organs
0.655 0.345 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.655 0.345 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.655 0.345 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.655 0.345 0.000
S31 Open wound of abdomen, lower back and pelvis
0.655 0.345 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.655 0.345 0.000
M25.56 Pain in joint (Lower leg)
0.654 0.346 0.000
W08 Fall involving other furniture
0.654 0.346 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.654 0.346 0.000
I31.3 Pericardial effusion (noninflammatory)
0.653 0.347 0.000
M16.9 Coxarthrosis, unspecified
0.653 0.347 0.000
M76 Enthesopathies of lower limb, excluding foot
0.652 0.348 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.652 0.348 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.652 0.348 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.652 0.348 0.000
M06.0 Seronegative rheumatoid arthritis
0.651 0.349 0.000
V20-V29 Motorcycle rider injured in transport accident
0.651 0.349 0.000
B07 Viral warts
0.651 0.349 0.000
E53.8 Deficiency of other specified B group vitamins
0.651 0.349 0.000
M23.37 Other meniscus derangements-Capsular lig
0.651 0.349 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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