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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12425131
log Bayes Factor = 16.2355
Chromosome 12   position 82,984,879  (GRCh37) Explore rs12425131 on Ensembl!
Variant rs12425131 is listed in the   GWAS Catalog   ⇪
Variant rs12425131 is part of Cluster X0201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I50 Heart failure
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
N18 Chronic renal failure
0.997 0.003 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.991 0.009 0.000
N19 Unspecified renal failure
0.986 0.014 0.000
S60-S69 Injuries to the wrist and hand
0.986 0.014 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.984 0.016 0.000
Chapter II Neoplasms
0.983 0.017 0.000
E10-E14 Diabetes mellitus
0.982 0.018 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.982 0.018 0.000
I50.0 Congestive heart failure
0.980 0.020 0.000
I25.2 Old myocardial infarction
0.977 0.023 0.000
C78.7 Secondary malignant neoplasm of liver
0.973 0.027 0.000
B95-B98 Bacterial, viral and other infectious agents
0.972 0.028 0.000
I50.9 Heart failure, unspecified
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
E87.5 Hyperkalaemia
0.965 0.035 0.000
N25-N29 Other disorders of kidney and ureter
0.958 0.042 0.000
S00-S09 Injuries to the head
0.955 0.045 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.955 0.045 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.954 0.046 0.000
N18.9 Chronic renal failure, unspecified
0.954 0.046 0.000
C79 Secondary malignant neoplasm of other sites
0.953 0.047 0.000
E10 Insulin-dependent diabetes mellitus
0.942 0.058 0.000
A30-A49 Other bacterial diseases
0.939 0.061 0.000
Chapter V Mental and behavioural disorders
0.934 0.066 0.000
E65-E68 Obesity and other hyperalimentation
0.932 0.068 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.924 0.076 0.000
E87.6 Hypokalaemia
0.922 0.078 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.921 0.079 0.000
E11 Non-insulin-dependent diabetes mellitus
0.920 0.080 0.000
I50.1 Left ventricular failure
0.915 0.085 0.000
N18.0 End-stage renal disease
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.910 0.090 0.000
E86 Volume depletion
0.908 0.092 0.000
C78.0 Secondary malignant neoplasm of lung
0.907 0.093 0.000
I24 Other acute ischaemic heart diseases
0.907 0.093 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.906 0.094 0.000
Chapter VI Diseases of the nervous system
0.903 0.097 0.000
E10.9 Without complications
0.898 0.102 0.000
S61 Open wound of wrist and hand
0.892 0.108 0.000
N18.3 Chronic kidney disease, stage 3
0.891 0.109 0.000
I49 Other cardiac arrhythmias
0.886 0.114 0.000
E66 Obesity
0.883 0.117 0.000
S90-S99 Injuries to the ankle and foot
0.880 0.120 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.878 0.122 0.000
E87.0 Hyperosmolality and hypernatraemia
0.874 0.126 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.870 0.130 0.000
I21 Acute myocardial infarction
0.862 0.138 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.862 0.138 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.860 0.140 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.859 0.141 0.000
E87.7 Fluid overload
0.856 0.144 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.855 0.145 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.853 0.147 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.851 0.149 0.000
G40-G47 Episodic and paroxysmal disorders
0.849 0.151 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.848 0.152 0.000
I21.4 Acute subendocardial myocardial infarction
0.846 0.154 0.000
N10-N16 Renal tubulo-interstitial diseases
0.844 0.156 0.000
E66.8 Other obesity
0.841 0.159 0.000
N18.5 Chronic kidney disease, stage 5
0.838 0.162 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.838 0.162 0.000
I42 Cardiomyopathy
0.834 0.165 0.000
S00 Superficial injury of head
0.834 0.166 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.833 0.167 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.827 0.173 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.822 0.178 0.000
S64 Injury of nerves at wrist and hand level
0.822 0.178 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.821 0.179 0.000
C78.2 Secondary malignant neoplasm of pleura
0.820 0.180 0.000
I25.3 Aneurysm of heart
0.819 0.180 0.000
Q60-Q64 Congenital malformations of the urinary system
0.819 0.181 0.000
W20-W49 Exposure to inanimate mechanical forces
0.819 0.181 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.818 0.182 0.000
E11.5 With peripheral circulatory complications
0.817 0.183 0.000
E11.4 With neurological complications
0.814 0.186 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.812 0.188 0.000
A46 Erysipelas
0.810 0.190 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.810 0.190 0.000
S01 Open wound of head
0.808 0.192 0.000
N18.8 Other chronic renal failure
0.807 0.193 0.000
N17 Acute renal failure
0.806 0.194 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.806 0.194 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.805 0.195 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.804 0.196 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.801 0.199 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.798 0.202 0.000
T66-T78 Other and unspecified effects of external causes
0.796 0.204 0.000
S92 Fracture of foot, except ankle
0.794 0.206 0.000
E87.2 Acidosis
0.793 0.207 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.792 0.208 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.791 0.209 0.000
A40 Streptococcal septicaemia
0.785 0.215 0.000
S02 Fracture of skull and facial bones
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.783 0.217 0.000
I49.9 Cardiac arrhythmia, unspecified
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.781 0.219 0.000
F30-F39 Mood [affective] disorders
0.778 0.221 0.000
I44 Atrioventricular and left bundle-branch block
0.778 0.222 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.777 0.223 0.000
A49 Bacterial infection of unspecified site
0.775 0.224 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.775 0.225 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.775 0.225 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.774 0.226 0.000
I36 Nonrheumatic tricuspid valve disorders
0.772 0.228 0.000
S06 Intracranial injury
0.770 0.230 0.000
S80-S89 Injuries to the knee and lower leg
0.770 0.230 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.769 0.231 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.768 0.232 0.000
G40 Epilepsy
0.764 0.236 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.764 0.236 0.000
D10-D36 Benign neoplasms
0.764 0.236 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.764 0.236 0.000
I35 Nonrheumatic aortic valve disorders
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.762 0.238 0.000
I33 Acute and subacute endocarditis
0.760 0.240 0.000
S60 Superficial injury of wrist and hand
0.759 0.241 0.000
I45 Other conduction disorders
0.759 0.241 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.756 0.244 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.755 0.245 0.000
I95 Hypotension
0.754 0.246 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.751 0.249 0.000
N18.4 Chronic kidney disease, stage 4
0.751 0.249 0.000
Q61 Cystic kidney disease
0.749 0.251 0.000
T92 Sequelae of injuries of upper limb
0.749 0.251 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.749 0.251 0.000
G90-G99 Other disorders of the nervous system
0.749 0.251 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.748 0.252 0.000
I49.1 Atrial premature depolarisation
0.747 0.253 0.000
N28.1 Cyst of kidney, acquired
0.747 0.253 0.000
E11.2 With renal complications
0.746 0.254 0.000
E10.3 With ophthalmic complications
0.746 0.254 0.000
T82.1 Mechanical complication of cardiac electronic device
0.744 0.256 0.000
S62 Fracture at wrist and hand level
0.744 0.256 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.743 0.257 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.742 0.258 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.741 0.259 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
S69 Other and unspecified injuries of wrist and hand
0.736 0.263 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.736 0.264 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.736 0.264 0.000
E88 Other metabolic disorders
0.736 0.264 0.000
B15-B19 Viral hepatitis
0.736 0.264 0.000
A80-A89 Viral infections of the central nervous system
0.736 0.264 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.735 0.265 0.000
E11.0 With coma
0.733 0.266 0.000
G47 Sleep disorders
0.732 0.268 0.000
N28.0 Ischaemia and infarction of kidney
0.731 0.269 0.000
S20-S29 Injuries to the thorax
0.729 0.270 0.000
I60-I69 Cerebrovascular diseases
0.729 0.271 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.729 0.271 0.000
V10-V19 Pedal cyclist injured in transport accident
0.727 0.273 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.726 0.274 0.000
N00-N08 Glomerular diseases
0.725 0.275 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.725 0.275 0.000
F60-F69 Disorders of adult personality and behaviour
0.724 0.276 0.000
A41 Other septicaemia
0.723 0.277 0.000
E10.5 With peripheral circulatory complications
0.723 0.277 0.000
I49.4 Other and unspecified premature depolarisation
0.721 0.279 0.000
I25.5 Ischaemic cardiomyopathy
0.720 0.280 0.000
S61.0 Open wound of finger(s) without damage to nail
0.720 0.280 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.719 0.280 0.000
Chapter X Diseases of the respiratory system
0.719 0.281 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.719 0.281 0.000
N26 Unspecified contracted kidney
0.719 0.281 0.000
N13 Obstructive and reflux uropathy
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I95.1 Orthostatic hypotension
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.283 0.000
I25.4 Coronary artery aneurysm
0.716 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
N18.1 Chronic kidney disease, stage 1
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.285 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.713 0.286 0.000
E87.4 Mixed disorder of acid-base balance
0.713 0.286 0.000
E87.3 Alkalosis
0.713 0.286 0.000
I73 Other peripheral vascular diseases
0.713 0.287 0.000
S00.0 Superficial injury of scalp
0.711 0.289 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.711 0.289 0.000
D00-D09 In situ neoplasms
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.710 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.289 0.000
B65-B83 Helminthiases
0.710 0.289 0.000
B50-B64 Protozoal diseases
0.710 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.289 0.000
A75-A79 Rickettsioses
0.710 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.289 0.000
A65-A69 Other spirochaetal diseases
0.710 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.289 0.000
A15-A19 Tuberculosis
0.710 0.289 0.000
T18 Foreign body in alimentary tract
0.710 0.290 0.000
Q50-Q56 Congenital malformations of genital organs
0.709 0.291 0.000
E10.4 With neurological complications
0.708 0.292 0.000
S67 Crushing injury of wrist and hand
0.708 0.292 0.000
D18 Haemangioma and lymphangioma, any site
0.707 0.293 0.000
S65 Injury of blood vessels at wrist and hand level
0.707 0.293 0.000
I30 Acute pericarditis
0.706 0.294 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.706 0.294 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.705 0.294 0.000
F32 Depressive episode
0.705 0.295 0.000
T81 Complications of procedures, not elsewhere classified
0.705 0.295 0.000
S68 Traumatic amputation of wrist and hand
0.705 0.295 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
S64.4 Injury of digital nerve of other finger
0.704 0.296 0.000
E13 Other specified diabetes mellitus
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.296 0.000
F80-F89 Disorders of psychological development
0.704 0.296 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.704 0.296 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.704 0.296 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.704 0.296 0.000
N60-N64 Disorders of breast
0.703 0.297 0.000
T17 Foreign body in respiratory tract
0.702 0.298 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.702 0.298 0.000
C80 Malignant neoplasm without specification of site
0.700 0.300 0.000
Y43 Primarily systemic agents
0.700 0.300 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.699 0.301 0.000
Y95 Nosocomial condition
0.699 0.301 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.697 0.303 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.696 0.304 0.000
Chapter XXII Codes for special purposes
0.695 0.305 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.695 0.305 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.305 0.000
Y10-Y34 Event of undetermined intent
0.694 0.305 0.000
Y00-Y09 Assault
0.694 0.305 0.000
X85-X99 Assault
0.694 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.305 0.000
X50-X57 Overexertion, travel and privation
0.694 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.694 0.305 0.000
X30-X39 Exposure to forces of nature
0.694 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.305 0.000
X10-X19 Contact with heat and hot substances
0.694 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.305 0.000
W75-W84 Other accidental threats to breathing
0.694 0.305 0.000
W65-W74 Accidental drowning and submersion
0.694 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.305 0.000
V95-V97 Air and space transport accidents
0.694 0.305 0.000
V90-V94 Water transport accidents
0.694 0.305 0.000
V80-V89 Other land transport accidents
0.694 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.694 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.305 0.000
E83 Disorders of mineral metabolism
0.694 0.306 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.694 0.306 0.000
I38 Endocarditis, valve unspecified
0.692 0.308 0.000
I42.9 Cardiomyopathy, unspecified
0.692 0.308 0.000
I34 Nonrheumatic mitral valve disorders
0.692 0.308 0.000
Y40 Systemic antibiotics
0.691 0.309 0.000
N28.8 Other specified disorders of kidney and ureter
0.690 0.310 0.000
I24.8 Other forms of acute ischaemic heart disease
0.689 0.311 0.000
E20-E35 Disorders of other endocrine glands
0.688 0.311 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.687 0.313 0.000
N27 Small kidney of unknown cause
0.687 0.313 0.000
N25 Disorders resulting from impaired renal tubular function
0.687 0.313 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.686 0.314 0.000
C73 Malignant neoplasm of thyroid gland
0.686 0.314 0.000
S08 Traumatic amputation of part of head
0.685 0.315 0.000
S07 Crushing injury of head
0.685 0.315 0.000
S05 Injury of eye and orbit
0.685 0.315 0.000
S04 Injury of cranial nerves
0.685 0.315 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.685 0.315 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.684 0.315 0.000
T87 Complications peculiar to reattachment and amputation
0.684 0.316 0.000
T86 Failure and rejection of transplanted organs and tissues
0.684 0.316 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.684 0.316 0.000
C79.6 Secondary malignant neoplasm of ovary
0.683 0.317 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.683 0.317 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.683 0.317 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.683 0.317 0.000
N18.2 Chronic kidney disease, stage 2
0.683 0.317 0.000
I35.0 Aortic (valve) stenosis
0.682 0.318 0.000
S70-S79 Injuries to the hip and thigh
0.681 0.319 0.000
S50-S59 Injuries to the elbow and forearm
0.681 0.319 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.679 0.321 0.000
G30-G32 Other degenerative diseases of the nervous system
0.678 0.322 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
E10.8 With unspecified complications
0.676 0.324 0.000
E10.7 With multiple complications
0.676 0.324 0.000
E10.6 With other specified complications
0.676 0.324 0.000
E10.2 With renal complications
0.676 0.324 0.000
E10.0 With coma
0.676 0.324 0.000
A40.8 Other streptococcal septicaemia
0.675 0.325 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.675 0.325 0.000
Q61.3 Polycystic kidney, unspecified
0.674 0.326 0.000
A48 Other bacterial diseases, not elsewhere classified
0.673 0.327 0.000
A44 Bartonellosis
0.673 0.327 0.000
A43 Nocardiosis
0.673 0.327 0.000
A42 Actinomycosis
0.673 0.327 0.000
A39 Meningococcal infection
0.673 0.327 0.000
A37 Whooping cough
0.673 0.327 0.000
A36 Diphtheria
0.673 0.327 0.000
A32 Listeriosis
0.673 0.327 0.000
A31 Infection due to other mycobacteria
0.673 0.327 0.000
A30 Leprosy [Hansen's disease]
0.673 0.327 0.000
A38 Scarlet fever
0.673 0.327 0.000
A35 Other tetanus
0.673 0.327 0.000
A34 Obstetrical tetanus
0.673 0.327 0.000
A33 Tetanus neonatorum
0.673 0.327 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.673 0.327 0.000
S01.4 Open wound of cheek and temporomandibular area
0.673 0.327 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.672 0.327 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.671 0.329 0.000
G47.3 Sleep apnoea
0.671 0.329 0.000
A49.0 Staphylococcal infection, unspecified
0.670 0.330 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.670 0.330 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.670 0.330 0.000
F70-F79 Mental retardation
0.670 0.330 0.000
E67 Other hyperalimentation
0.668 0.332 0.000
E68 Sequelae of hyperalimentation
0.668 0.332 0.000
E65 Localised adiposity
0.668 0.332 0.000
N17.9 Acute renal failure, unspecified
0.668 0.332 0.000
S02.6 Fracture of mandible
0.667 0.333 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.667 0.333 0.000
D18.0 Haemangioma, any site
0.667 0.333 0.000
F32.9 Depressive episode, unspecified
0.666 0.334 0.000
X60-X84 Intentional self-harm
0.666 0.334 0.000
I63 Cerebral infarction
0.665 0.335 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.665 0.335 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.665 0.335 0.000
I45.2 Bifascicular block
0.665 0.335 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.665 0.335 0.000
S92.0 Fracture of calcaneus
0.665 0.335 0.000
I31 Other diseases of pericardium
0.664 0.335 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.664 0.336 0.000
J90-J94 Other diseases of pleura
0.663 0.337 0.000
G41 Status epilepticus
0.662 0.337 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.662 0.338 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.662 0.338 0.000
S00.8 Superficial injury of other parts of head
0.661 0.339 0.000
E11.8 With unspecified complications
0.660 0.340 0.000
E11.7 With multiple complications
0.660 0.340 0.000
E11.6 With other specified complications
0.660 0.340 0.000
E11.1 With ketoacidosis
0.660 0.340 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.659 0.340 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.658 0.342 0.000
S40-S49 Injuries to the shoulder and upper arm
0.658 0.342 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.656 0.344 0.000
W29 Contact with other powered hand tools and household machinery
0.655 0.345 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.655 0.345 0.000
J40-J47 Chronic lower respiratory diseases
0.655 0.345 0.000
S01.3 Open wound of ear
0.654 0.346 0.000
I42.8 Other cardiomyopathies
0.653 0.347 0.000
Y52 Agents primarily affecting the cardiovascular system
0.653 0.347 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.653 0.347 0.000
S00.1 Contusion of eyelid and periocular area
0.652 0.347 0.000
G40.9 Epilepsy, unspecified
0.652 0.348 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.652 0.348 0.000
Q80-Q89 Other congenital malformations
0.652 0.348 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.652 0.348 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.652 0.348 0.000
Q35-Q37 Cleft lip and cleft palate
0.652 0.348 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.652 0.348 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.652 0.348 0.000
Q00-Q07 Congenital malformations of the nervous system
0.652 0.348 0.000
I24.1 Dressler's syndrome
0.650 0.350 0.000
I05-I09 Chronic rheumatic heart diseases
0.650 0.350 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.649 0.350 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.649 0.350 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.649 0.350 0.000
T82.3 Mechanical complication of other vascular grafts
0.649 0.350 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.649 0.350 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.649 0.350 0.000
T78 Adverse effects, not elsewhere classified
0.649 0.351 0.000
S92.4 Fracture of great toe
0.648 0.352 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.647 0.352 0.000
F11 Mental and behavioural disorders due to use of opioids
0.647 0.353 0.000
S09 Other and unspecified injuries of head
0.647 0.353 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.647 0.353 0.000
F99-F99 Unspecified mental disorder
0.647 0.353 0.000
Y44 Agents primarily affecting blood constituents
0.647 0.353 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.645 0.355 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.645 0.355 0.000
T85.2 Mechanical complication of intraocular lens
0.644 0.356 0.000
B35-B49 Mycoses
0.644 0.356 0.000
G44 Other headache syndromes
0.643 0.356 0.000
I27 Other pulmonary heart diseases
0.643 0.357 0.000
I73.0 Raynaud's syndrome
0.642 0.358 0.000
D10 Benign neoplasm of mouth and pharynx
0.641 0.359 0.000
E16 Other disorders of pancreatic internal secretion
0.641 0.359 0.000
S00.3 Superficial injury of nose
0.641 0.359 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.640 0.360 0.000
S61.7 Multiple open wounds of wrist and hand
0.640 0.360 0.000
T90 Sequelae of injuries of head
0.639 0.361 0.000
G20-G26 Extrapyramidal and movement disorders
0.639 0.361 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.638 0.362 0.000
S02.4 Fracture of malar and maxillary bones
0.636 0.363 0.000
S80 Superficial injury of lower leg
0.636 0.364 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.636 0.364 0.000
C81 Hodgkin's disease
0.636 0.364 0.000
I49.2 Junctional premature depolarisation
0.635 0.365 0.000
N40-N51 Diseases of male genital organs
0.635 0.365 0.000
N97 Female infertility
0.634 0.366 0.000
E66.1 Drug-induced obesity
0.633 0.367 0.000
E66.0 Obesity due to excess calories
0.633 0.367 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.632 0.368 0.000
S99 Other and unspecified injuries of ankle and foot
0.631 0.369 0.000
S98 Traumatic amputation of ankle and foot
0.631 0.369 0.000
S97 Crushing injury of ankle and foot
0.631 0.369 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.631 0.369 0.000
S95 Injury of blood vessels at ankle and foot level
0.631 0.369 0.000
S94 Injury of nerves at ankle and foot level
0.631 0.369 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.631 0.369 0.000
S91 Open wound of ankle and foot
0.631 0.369 0.000
S90 Superficial injury of ankle and foot
0.631 0.369 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.630 0.369 0.000
C79.2 Secondary malignant neoplasm of skin
0.630 0.370 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.629 0.370 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.629 0.370 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.629 0.370 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.629 0.370 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.629 0.370 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.629 0.370 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.629 0.370 0.000
S92.3 Fracture of metatarsal bone
0.629 0.370 0.000
S61.1 Open wound of finger(s) with damage to nail
0.629 0.371 0.000
W00-W19 Falls
0.628 0.372 0.000
S12 Fracture of neck
0.627 0.373 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.626 0.373 0.000
T92.1 Sequelae of fracture of arm
0.626 0.374 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.626 0.374 0.000
N20-N23 Urolithiasis
0.625 0.375 0.000
E10.1 With ketoacidosis
0.625 0.375 0.000
D36 Benign neoplasm of other and unspecified sites
0.624 0.376 0.000
N99-N99 Other disorders of the genitourinary system
0.624 0.376 0.000
I44.3 Other and unspecified atrioventricular block
0.623 0.377 0.000
G70-G73 Diseases of myoneural junction and muscle
0.622 0.378 0.000
S02.5 Fracture of tooth
0.622 0.378 0.000
T51 Toxic effect of alcohol
0.622 0.378 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.622 0.378 0.000
Y84.0 Cardiac catheterisation
0.621 0.379 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.621 0.379 0.000
S01.9 Open wound of head, part unspecified
0.620 0.380 0.000
T93 Sequelae of injuries of lower limb
0.618 0.381 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.618 0.382 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.618 0.382 0.000
B25-B34 Other viral diseases
0.618 0.382 0.000
T19 Foreign body in genito-urinary tract
0.618 0.382 0.000
T15 Foreign body on external eye
0.618 0.382 0.000
T16 Foreign body in ear
0.618 0.382 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.617 0.383 0.000
T98 Sequelae of other and unspecified effects of external causes
0.617 0.383 0.000
T95 Sequelae of burns, corrosions and frostbite
0.617 0.383 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.617 0.383 0.000
T91 Sequelae of injuries of neck and trunk
0.617 0.383 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.617 0.383 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.617 0.383 0.000
J47 Bronchiectasis
0.616 0.384 0.000
D11 Benign neoplasm of major salivary glands
0.614 0.386 0.000
I20 Angina pectoris
0.613 0.387 0.000
Y59 Other and unspecified vaccines and biological substances
0.613 0.387 0.000
Y58 Bacterial vaccines
0.613 0.387 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.613 0.387 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.613 0.387 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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