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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12586774
log Bayes Factor = 3.15733
Chromosome 14   position 26,129,566  (GRCh37) Explore rs12586774 on Ensembl!
Variant rs12586774 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
D10-D36 Benign neoplasms
0.990 0.010 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.976 0.024 0.000
C34 Malignant neoplasm of bronchus and lung
0.959 0.041 0.000
Chapter V Mental and behavioural disorders
0.950 0.050 0.000
Chapter XI Diseases of the digestive system
0.947 0.053 0.000
K55-K64 Other diseases of intestines
0.945 0.055 0.000
S80-S89 Injuries to the knee and lower leg
0.945 0.055 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.943 0.057 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
K59 Other functional intestinal disorders
0.940 0.060 0.000
K59.0 Constipation
0.939 0.061 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.931 0.069 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.920 0.080 0.000
D17 Benign lipomatous neoplasm
0.909 0.091 0.000
C64-C68 Malignant neoplasms of urinary tract
0.908 0.092 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.907 0.093 0.000
S82 Fracture of lower leg, including ankle
0.900 0.100 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.892 0.108 0.000
S70-S79 Injuries to the hip and thigh
0.888 0.112 0.000
K61 Abscess of anal and rectal regions
0.885 0.115 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.880 0.120 0.000
M80-M85 Disorders of bone density and structure
0.880 0.120 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.877 0.123 0.000
K40-K46 Hernia
0.877 0.123 0.000
K57 Diverticular disease of intestine
0.876 0.124 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.875 0.125 0.000
S50-S59 Injuries to the elbow and forearm
0.873 0.127 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.871 0.129 0.000
C67 Malignant neoplasm of bladder
0.869 0.131 0.000
C34.3 Lower lobe, bronchus or lung
0.869 0.131 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.865 0.135 0.000
K43 Ventral hernia
0.864 0.136 0.000
D12.2 Ascending colon
0.860 0.140 0.000
D24 Benign neoplasm of breast
0.858 0.142 0.000
Chapter XX External causes of morbidity and mortality
0.858 0.142 0.000
D36 Benign neoplasm of other and unspecified sites
0.854 0.146 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.854 0.146 0.000
C34.9 Bronchus or lung, unspecified
0.851 0.149 0.000
D00-D09 In situ neoplasms
0.851 0.149 0.000
B95-B98 Bacterial, viral and other infectious agents
0.848 0.152 0.000
F10.3 Withdrawal state
0.848 0.152 0.000
M05-M14 Inflammatory polyarthropathies
0.848 0.152 0.000
S82.8 Fractures of other parts of lower leg
0.847 0.153 0.000
K61.0 Anal abscess
0.843 0.157 0.000
C67.9 Bladder, unspecified
0.833 0.167 0.000
M81 Osteoporosis without pathological fracture
0.831 0.169 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.830 0.170 0.000
Chapter VI Diseases of the nervous system
0.827 0.173 0.000
C15-C26 Malignant neoplasms of digestive organs
0.826 0.174 0.000
M45-M49 Spondylopathies
0.821 0.179 0.000
S32 Fracture of lumbar spine and pelvis
0.817 0.183 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.816 0.184 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.814 0.186 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.809 0.191 0.000
S70 Superficial injury of hip and thigh
0.801 0.199 0.000
S40-S49 Injuries to the shoulder and upper arm
0.798 0.202 0.000
M13 Other arthritis
0.796 0.204 0.000
C34.1 Upper lobe, bronchus or lung
0.795 0.205 0.000
D12.0 Caecum
0.795 0.205 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.791 0.209 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.790 0.210 0.000
S20-S29 Injuries to the thorax
0.790 0.210 0.000
F30-F39 Mood [affective] disorders
0.788 0.212 0.000
C18 Malignant neoplasm of colon
0.787 0.213 0.000
D12.3 Transverse colon
0.785 0.215 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.784 0.216 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
W00-W19 Falls
0.781 0.219 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.781 0.219 0.000
S51 Open wound of forearm
0.781 0.219 0.000
B35-B49 Mycoses
0.781 0.219 0.000
D32 Benign neoplasm of meninges
0.776 0.224 0.000
C34.2 Middle lobe, bronchus or lung
0.774 0.226 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.773 0.227 0.000
M81.9 Osteoporosis, unspecified
0.773 0.227 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.771 0.229 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.770 0.230 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.768 0.232 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.765 0.235 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.765 0.235 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
K56.6 Other and unspecified intestinal obstruction
0.764 0.236 0.000
S82.6 Fracture of lateral malleolus
0.764 0.236 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.759 0.241 0.000
M13.9 Arthritis, unspecified
0.759 0.241 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.757 0.243 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.753 0.247 0.000
M46 Other inflammatory spondylopathies
0.753 0.247 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.751 0.249 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.750 0.250 0.000
K65-K67 Diseases of peritoneum
0.749 0.251 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.746 0.254 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.746 0.254 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.745 0.255 0.000
C34.0 Main bronchus
0.745 0.255 0.000
C18.7 Sigmoid colon
0.744 0.256 0.000
F10.2 Dependence syndrome
0.743 0.257 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.741 0.259 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.741 0.259 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.741 0.259 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.740 0.259 0.000
C92 Myeloid leukaemia
0.739 0.261 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.738 0.262 0.000
D22 Melanocytic naevi
0.734 0.266 0.000
S82.4 Fracture of fibula alone
0.731 0.269 0.000
K59.3 Megacolon, not elsewhere classified
0.730 0.270 0.000
D12.7 Rectosigmoid junction
0.727 0.273 0.000
K70-K77 Diseases of liver
0.726 0.274 0.000
S82.5 Fracture of medial malleolus
0.726 0.274 0.000
S81 Open wound of lower leg
0.724 0.276 0.000
M11 Other crystal arthropathies
0.723 0.277 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.722 0.278 0.000
D18 Haemangioma and lymphangioma, any site
0.720 0.280 0.000
O60-O75 Complications of labour and delivery
0.718 0.282 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
D34 Benign neoplasm of thyroid gland
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
C51-C58 Malignant neoplasms of female genital organs
0.711 0.289 0.000
D31 Benign neoplasm of eye and adnexa
0.709 0.290 0.000
D30 Benign neoplasm of urinary organs
0.709 0.290 0.000
D29 Benign neoplasm of male genital organs
0.709 0.290 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.709 0.290 0.000
D26 Other benign neoplasms of uterus
0.709 0.290 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.709 0.290 0.000
D19 Benign neoplasm of mesothelial tissue
0.709 0.290 0.000
D16 Benign neoplasm of bone and articular cartilage
0.709 0.290 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.709 0.290 0.000
D10 Benign neoplasm of mouth and pharynx
0.709 0.290 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.708 0.292 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.708 0.292 0.000
D06 Carcinoma in situ of cervix uteri
0.707 0.293 0.000
S80 Superficial injury of lower leg
0.704 0.296 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.704 0.296 0.000
C67.6 Ureteric orifice
0.702 0.298 0.000
M86-M90 Other osteopathies
0.702 0.298 0.000
W19 Unspecified fall
0.702 0.298 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.702 0.298 0.000
F60-F69 Disorders of adult personality and behaviour
0.701 0.298 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.700 0.300 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.700 0.300 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.700 0.300 0.000
C32 Malignant neoplasm of larynx
0.700 0.300 0.000
C31 Malignant neoplasm of accessory sinuses
0.700 0.300 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.700 0.300 0.000
C37 Malignant neoplasm of thymus
0.700 0.300 0.000
C33 Malignant neoplasm of trachea
0.700 0.300 0.000
D27 Benign neoplasm of ovary
0.699 0.301 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.693 0.307 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.692 0.308 0.000
G30-G32 Other degenerative diseases of the nervous system
0.692 0.308 0.000
T40.2 Other opioids
0.690 0.310 0.000
D23 Other benign neoplasms of skin
0.690 0.310 0.000
G90-G99 Other disorders of the nervous system
0.689 0.311 0.000
K56.4 Other impaction of intestine
0.689 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.688 0.311 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.688 0.311 0.000
M80 Osteoporosis with pathological fracture
0.688 0.312 0.000
C34.8 Overlapping lesion of bronchus and lung
0.688 0.312 0.000
M45 Ankylosing spondylitis
0.687 0.312 0.000
M81.4 Drug-induced osteoporosis
0.687 0.313 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.685 0.315 0.000
F10.4 Withdrawal state with delirium
0.685 0.315 0.000
F10.1 Harmful use
0.684 0.316 0.000
S72 Fracture of femur
0.682 0.318 0.000
B15-B19 Viral hepatitis
0.682 0.318 0.000
F80-F89 Disorders of psychological development
0.681 0.318 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.681 0.319 0.000
F70-F79 Mental retardation
0.681 0.319 0.000
B25-B34 Other viral diseases
0.678 0.322 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.677 0.322 0.000
S88 Traumatic amputation of lower leg
0.677 0.323 0.000
S87 Crushing injury of lower leg
0.677 0.323 0.000
S86 Injury of muscle and tendon at lower leg level
0.677 0.323 0.000
S85 Injury of blood vessels at lower leg level
0.677 0.323 0.000
S84 Injury of nerves at lower leg level
0.677 0.323 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.676 0.324 0.000
S37 Injury of urinary and pelvic organs
0.676 0.324 0.000
S36 Injury of intra-abdominal organs
0.676 0.324 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.676 0.324 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.676 0.324 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.676 0.324 0.000
S31 Open wound of abdomen, lower back and pelvis
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.674 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.674 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.325 0.000
B65-B83 Helminthiases
0.674 0.325 0.000
B50-B64 Protozoal diseases
0.674 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.674 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.674 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.674 0.325 0.000
A75-A79 Rickettsioses
0.674 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.674 0.325 0.000
A65-A69 Other spirochaetal diseases
0.674 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.674 0.325 0.000
A15-A19 Tuberculosis
0.674 0.325 0.000
K59.9 Functional intestinal disorder, unspecified
0.674 0.326 0.000
K59.4 Anal spasm
0.674 0.326 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.674 0.326 0.000
A30-A49 Other bacterial diseases
0.673 0.326 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.673 0.327 0.000
S32.0 Fracture of lumbar vertebra
0.672 0.327 0.000
F31 Bipolar affective disorder
0.671 0.328 0.000
D12.5 Sigmoid colon
0.671 0.329 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.670 0.330 0.000
S51.9 Open wound of forearm, part unspecified
0.669 0.331 0.000
F03 Unspecified dementia
0.668 0.332 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.668 0.332 0.000
M60-M63 Disorders of muscles
0.668 0.332 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.666 0.333 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.666 0.334 0.000
S82.60 Fracture of lateral malleolus (closed)
0.666 0.334 0.000
X60-X84 Intentional self-harm
0.665 0.335 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.665 0.335 0.000
X50-X57 Overexertion, travel and privation
0.662 0.338 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.662 0.338 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.662 0.338 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.662 0.338 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.661 0.339 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.661 0.339 0.000
F33 Recurrent depressive disorder
0.661 0.339 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.660 0.340 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.660 0.340 0.000
D12.9 Anus and anal canal
0.660 0.340 0.000
D12.1 Appendix
0.660 0.340 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.659 0.341 0.000
F00 Dementia in Alzheimer's disease
0.659 0.341 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.657 0.343 0.000
O16 Unspecified maternal hypertension
0.656 0.344 0.000
B37 Candidiasis
0.656 0.344 0.000
D35.1 Parathyroid gland
0.656 0.344 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.655 0.345 0.000
S89 Other and unspecified injuries of lower leg
0.655 0.345 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.655 0.345 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.654 0.345 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.654 0.345 0.000
C91 Lymphoid leukaemia
0.654 0.346 0.000
C18.3 Hepatic flexure
0.654 0.346 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.654 0.346 0.000
K56.1 Intussusception
0.653 0.347 0.000
C17 Malignant neoplasm of small intestine
0.653 0.347 0.000
T91 Sequelae of injuries of neck and trunk
0.653 0.347 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.652 0.347 0.000
A00-A09 Intestinal infectious diseases
0.653 0.347 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.652 0.348 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.652 0.348 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.652 0.348 0.000
D03 Melanoma in situ
0.652 0.348 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.651 0.349 0.000
C66 Malignant neoplasm of ureter
0.651 0.349 0.000
C65 Malignant neoplasm of renal pelvis
0.651 0.349 0.000
C60-C63 Malignant neoplasms of male genital organs
0.651 0.349 0.000
W10 Fall on and from stairs and steps
0.651 0.349 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.650 0.350 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.650 0.350 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.650 0.350 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.650 0.350 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.650 0.350 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.650 0.350 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.650 0.350 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.650 0.350 0.000
T36 Poisoning by systemic antibiotics
0.650 0.350 0.000
W50-W64 Exposure to animate mechanical forces
0.650 0.350 0.000
S51.8 Open wound of other parts of forearm
0.649 0.351 0.000
V80-V89 Other land transport accidents
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.648 0.352 0.000
B07 Viral warts
0.648 0.352 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.648 0.352 0.000
D36.7 Other specified sites
0.647 0.353 0.000
K70 Alcoholic liver disease
0.646 0.354 0.000
S82.9 Fracture of lower leg, part unspecified
0.645 0.355 0.000
S82.7 Multiple fractures of lower leg
0.645 0.355 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.645 0.355 0.000
K90-K93 Other diseases of the digestive system
0.644 0.356 0.000
S90-S99 Injuries to the ankle and foot
0.644 0.356 0.000
V10-V19 Pedal cyclist injured in transport accident
0.642 0.358 0.000
X20-X29 Contact with venomous animals and plants
0.642 0.358 0.000
T51 Toxic effect of alcohol
0.641 0.359 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.641 0.359 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.640 0.360 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.640 0.360 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.640 0.360 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.640 0.360 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.640 0.360 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.640 0.360 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.640 0.360 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.640 0.360 0.000
F11 Mental and behavioural disorders due to use of opioids
0.640 0.360 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.639 0.361 0.000
S78 Traumatic amputation of hip and thigh
0.637 0.363 0.000
S77 Crushing injury of hip and thigh
0.637 0.363 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.637 0.363 0.000
S75 Injury of blood vessels at hip and thigh level
0.637 0.363 0.000
S74 Injury of nerves at hip and thigh level
0.637 0.363 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.637 0.363 0.000
S71 Open wound of hip and thigh
0.637 0.363 0.000
S52 Fracture of forearm
0.636 0.364 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.636 0.364 0.000
M13.98 Arthritis, unspecified (Other)
0.635 0.365 0.000
K61.4 Intrasphincteric abscess
0.635 0.365 0.000
K61.3 Ischiorectal abscess
0.635 0.365 0.000
K61.2 Anorectal abscess
0.635 0.365 0.000
K61.1 Rectal abscess
0.635 0.365 0.000
M11.2 Other chondrocalcinosis
0.634 0.365 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.634 0.366 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.634 0.366 0.000
K41 Femoral hernia
0.634 0.366 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.633 0.367 0.000
F99-F99 Unspecified mental disorder
0.632 0.368 0.000
C92.0 Acute myeloid leukaemia
0.631 0.369 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.631 0.369 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.631 0.369 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.631 0.369 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.631 0.369 0.000
M83 Adult osteomalacia
0.631 0.369 0.000
M82 Osteoporosis in diseases classified elsewhere
0.631 0.369 0.000
W19.2 School, other institution and public administrative area
0.630 0.370 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.630 0.370 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.629 0.371 0.000
K56.3 Gallstone ileus
0.629 0.371 0.000
K56.0 Paralytic ileus
0.629 0.371 0.000
K45 Other abdominal hernia
0.629 0.371 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.629 0.371 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.628 0.372 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.628 0.372 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.628 0.372 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.628 0.372 0.000
F10.9 Unspecified mental and behavioural disorder
0.628 0.372 0.000
F10.8 Other mental and behavioural disorders
0.628 0.372 0.000
F10.7 Residual and late-onset psychotic disorder
0.628 0.372 0.000
F10.6 Amnesic syndrome
0.628 0.372 0.000
F10.5 Psychotic disorder
0.628 0.372 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.627 0.373 0.000
K46 Unspecified abdominal hernia
0.627 0.373 0.000
C81 Hodgkin's disease
0.627 0.373 0.000
D11 Benign neoplasm of major salivary glands
0.626 0.373 0.000
S59 Other and unspecified injuries of forearm
0.626 0.374 0.000
S58 Traumatic amputation of forearm
0.626 0.374 0.000
S57 Crushing injury of forearm
0.626 0.374 0.000
S56 Injury of muscle and tendon at forearm level
0.626 0.374 0.000
S55 Injury of blood vessels at forearm level
0.626 0.374 0.000
S54 Injury of nerves at forearm level
0.626 0.374 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.626 0.374 0.000
S50 Superficial injury of forearm
0.626 0.374 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.624 0.375 0.000
C95 Leukaemia of unspecified cell type
0.624 0.375 0.000
C94 Other leukaemias of specified cell type
0.624 0.375 0.000
C93 Monocytic leukaemia
0.624 0.375 0.000
C88 Malignant immunoproliferative diseases
0.624 0.375 0.000
C86 Other specified types of T/NK-cell lymphoma
0.624 0.375 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.624 0.375 0.000
M65-M68 Disorders of synovium and tendon
0.625 0.375 0.000
C67.8 Overlapping lesion of bladder
0.623 0.377 0.000
C67.7 Urachus
0.623 0.377 0.000
C67.5 Bladder neck
0.623 0.377 0.000
C67.4 Posterior wall of bladder
0.623 0.377 0.000
C67.3 Anterior wall of bladder
0.623 0.377 0.000
C67.1 Dome of bladder
0.623 0.377 0.000
C67.0 Trigone of bladder
0.623 0.377 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.622 0.377 0.000
D32.0 Cerebral meninges
0.622 0.378 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.622 0.378 0.000
Q50-Q56 Congenital malformations of genital organs
0.622 0.378 0.000
M13.94 Arthritis, unspecified (Hand)
0.622 0.378 0.000
K65 Peritonitis
0.621 0.379 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.620 0.380 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.619 0.381 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.619 0.381 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.619 0.381 0.000
K43.4 Parastomal hernia with gangrene
0.619 0.381 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.619 0.381 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.619 0.381 0.000
K43.1 Ventral hernia with gangrene
0.619 0.381 0.000
S82.3 Fracture of lower end of tibia
0.619 0.381 0.000
M85 Other disorders of bone density and structure
0.618 0.382 0.000
M70-M79 Other soft tissue disorders
0.618 0.382 0.000
S00-S09 Injuries to the head
0.617 0.383 0.000
C18.5 Splenic flexure
0.616 0.384 0.000
T42.4 Benzodiazepines
0.616 0.384 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.616 0.384 0.000
K59.1 Functional diarrhoea
0.615 0.385 0.000
Y35-Y36 Legal intervention and operations of war
0.615 0.385 0.000
Y10-Y34 Event of undetermined intent
0.615 0.385 0.000
Y00-Y09 Assault
0.615 0.385 0.000
X85-X99 Assault
0.615 0.385 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.615 0.385 0.000
X30-X39 Exposure to forces of nature
0.615 0.385 0.000
X10-X19 Contact with heat and hot substances
0.615 0.385 0.000
X00-X09 Exposure to smoke, fire and flames
0.615 0.385 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.615 0.385 0.000
W75-W84 Other accidental threats to breathing
0.615 0.385 0.000
W65-W74 Accidental drowning and submersion
0.615 0.385 0.000
V98-V99 Other and unspecified transport accidents
0.615 0.385 0.000
V95-V97 Air and space transport accidents
0.615 0.385 0.000
V90-V94 Water transport accidents
0.615 0.385 0.000
V70-V79 Bus occupant injured in transport accident
0.615 0.385 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.615 0.385 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.615 0.385 0.000
V40-V49 Car occupant injured in transport accident
0.615 0.385 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.615 0.385 0.000
V01-V09 Pedestrian injured in transport accident
0.615 0.385 0.000
S79 Other and unspecified injuries of hip and thigh
0.614 0.386 0.000
T13 Other injuries of lower limb, level unspecified
0.614 0.386 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.613 0.387 0.000
D36.9 Benign neoplasm of unspecified site
0.612 0.387 0.000
D36.0 Lymph nodes
0.612 0.387 0.000
T78 Adverse effects, not elsewhere classified
0.612 0.388 0.000
D09 Carcinoma in situ of other and unspecified sites
0.611 0.389 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.610 0.390 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.610 0.390 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.610 0.390 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.610 0.390 0.000
D05 Carcinoma in situ of breast
0.610 0.390 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.610 0.390 0.000
S82.40 Fracture of fibula alone (closed)
0.609 0.391 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.609 0.391 0.000
K56.2 Volvulus
0.609 0.391 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.609 0.391 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.609 0.391 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.608 0.391 0.000
M14 Arthropathies in other diseases classified elsewhere
0.608 0.392 0.000
M12 Other specific arthropathies
0.608 0.392 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.608 0.392 0.000
M08 Juvenile arthritis
0.608 0.392 0.000
M10 Gout
0.608 0.392 0.000
C18.0 Caecum
0.608 0.392 0.000
S82.86 Maisonneuve's fracture
0.607 0.392 0.000
S82.81 Fractures of other parts of lower leg (open)
0.607 0.392 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.606 0.394 0.000
S32.4 Fracture of acetabulum
0.606 0.394 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.605 0.395 0.000
G61 Inflammatory polyneuropathy
0.605 0.395 0.000
S40 Superficial injury of shoulder and upper arm
0.605 0.395 0.000
S32.5 Fracture of pubis
0.605 0.395 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.604 0.395 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.604 0.396 0.000
D06.9 Cervix, unspecified
0.604 0.396 0.000
Chapter VIII Diseases of the ear and mastoid process
0.603 0.397 0.000
T92 Sequelae of injuries of upper limb
0.603 0.397 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.603 0.397 0.000
S82.50 Fracture of medial malleolus (closed)
0.601 0.399 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.601 0.399 0.000
D12.6 Colon, unspecified
0.599 0.401 0.000
S82.0 Fracture of patella
0.598 0.402 0.000
D37.4 Colon
0.598 0.402 0.000
S20 Superficial injury of thorax
0.597 0.402 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.597 0.403 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.597 0.403 0.000
M81.8 Other osteoporosis
0.595 0.404 0.000
M81.6 Localised osteoporosis [Lequesne]
0.595 0.404 0.000
M81.5 Idiopathic osteoporosis
0.595 0.404 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.595 0.404 0.000
M81.2 Osteoporosis of disuse
0.595 0.404 0.000
M81.1 Postoophorectomy osteoporosis
0.595 0.404 0.000
M81.0 Postmenopausal osteoporosis
0.595 0.404 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.595 0.405 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.595 0.405 0.000
S30.2 Contusion of external genital organs
0.595 0.405 0.000
S30.1 Contusion of abdominal wall
0.595 0.405 0.000
S30.0 Contusion of lower back and pelvis
0.595 0.405 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.595 0.405 0.000
M81.98 Osteoporosis, unspecified (Other)
0.595 0.405 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.595 0.405 0.000
D37.5 Rectum
0.594 0.406 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.593 0.407 0.000
D47.1 Chronic myeloproliferative disease
0.593 0.407 0.000
M40-M43 Deforming dorsopathies
0.593 0.407 0.000
W20-W49 Exposure to inanimate mechanical forces
0.593 0.407 0.000
K56.7 Ileus, unspecified
0.593 0.407 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.593 0.407 0.000
C21 Malignant neoplasm of anus and anal canal
0.593 0.407 0.000
C23 Malignant neoplasm of gallbladder
0.593 0.407 0.000
G81 Hemiplegia
0.591 0.409 0.000
S19 Other and unspecified injuries of neck
0.589 0.411 0.000
L40-L45 Papulosquamous disorders
0.589 0.411 0.000
M49 Spondylopathies in diseases classified elsewhere
0.589 0.411 0.000
C67.2 Lateral wall of bladder
0.588 0.411 0.000
G70-G73 Diseases of myoneural junction and muscle
0.588 0.412 0.000
F01 Vascular dementia
0.588 0.412 0.000
C71 Malignant neoplasm of brain
0.588 0.412 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.586 0.414 0.000
S32.3 Fracture of ilium
0.586 0.414 0.000
S32.2 Fracture of coccyx
0.586 0.414 0.000
S32.1 Fracture of sacrum
0.586 0.414 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.585 0.415 0.000
F02 Dementia in other diseases classified elsewhere
0.585 0.415 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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