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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12603526
log Bayes Factor = 5.55678
Chromosome 17   position 800,593  (GRCh37) Explore rs12603526 on Ensembl!
Variant rs12603526 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
M35 Other systemic involvement of connective tissue
0.979 0.021 0.000
C15 Malignant neoplasm of oesophagus
0.974 0.026 0.000
C18 Malignant neoplasm of colon
0.972 0.028 0.000
M35.0 Sicca syndrome [Sjogren]
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.959 0.041 0.000
N10-N16 Renal tubulo-interstitial diseases
0.948 0.052 0.000
Chapter XX External causes of morbidity and mortality
0.946 0.054 0.000
E10-E14 Diabetes mellitus
0.935 0.065 0.000
C16 Malignant neoplasm of stomach
0.931 0.069 0.000
D10-D36 Benign neoplasms
0.930 0.070 0.000
N25-N29 Other disorders of kidney and ureter
0.926 0.074 0.000
C20 Malignant neoplasm of rectum
0.924 0.076 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.923 0.077 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.921 0.079 0.000
C15.9 Oesophagus, unspecified
0.919 0.081 0.000
E10 Insulin-dependent diabetes mellitus
0.917 0.083 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.917 0.083 0.000
M80-M85 Disorders of bone density and structure
0.914 0.086 0.000
N99-N99 Other disorders of the genitourinary system
0.911 0.089 0.000
M65-M68 Disorders of synovium and tendon
0.908 0.092 0.000
N00-N08 Glomerular diseases
0.906 0.094 0.000
C17 Malignant neoplasm of small intestine
0.899 0.101 0.000
N13 Obstructive and reflux uropathy
0.897 0.103 0.000
M70-M79 Other soft tissue disorders
0.894 0.106 0.000
C79 Secondary malignant neoplasm of other sites
0.893 0.107 0.000
N17-N19 Renal failure
0.891 0.109 0.000
Chapter VIII Diseases of the ear and mastoid process
0.891 0.109 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.888 0.112 0.000
M21 Other acquired deformities of limbs
0.887 0.113 0.000
E10.9 Without complications
0.886 0.114 0.000
D12.3 Transverse colon
0.885 0.115 0.000
N60-N64 Disorders of breast
0.882 0.118 0.000
C15.5 Lower third of oesophagus
0.882 0.118 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.877 0.123 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.874 0.126 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.873 0.127 0.000
Chapter VI Diseases of the nervous system
0.872 0.128 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.869 0.131 0.000
M34 Systemic sclerosis
0.866 0.134 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.861 0.139 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.858 0.142 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.857 0.143 0.000
C64-C68 Malignant neoplasms of urinary tract
0.855 0.145 0.000
C18.9 Colon, unspecified
0.855 0.145 0.000
M91-M94 Chondropathies
0.853 0.147 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.851 0.149 0.000
M24 Other specific joint derangements
0.847 0.153 0.000
C16.9 Stomach, unspecified
0.847 0.153 0.000
D12.5 Sigmoid colon
0.845 0.155 0.000
N13.3 Other and unspecified hydronephrosis
0.842 0.158 0.000
H65-H75 Diseases of middle ear and mastoid
0.840 0.160 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.838 0.162 0.000
N61 Inflammatory disorders of breast
0.838 0.162 0.000
M79.8 Other specified soft tissue disorders
0.835 0.165 0.000
C18.7 Sigmoid colon
0.834 0.166 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.831 0.169 0.000
C18.2 Ascending colon
0.829 0.171 0.000
N17 Acute renal failure
0.823 0.177 0.000
Y52 Agents primarily affecting the cardiovascular system
0.820 0.180 0.000
E00-E07 Disorders of thyroid gland
0.812 0.188 0.000
M81 Osteoporosis without pathological fracture
0.809 0.191 0.000
G57 Mononeuropathies of lower limb
0.804 0.196 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.804 0.196 0.000
N30-N39 Other diseases of urinary system
0.801 0.199 0.000
D00-D09 In situ neoplasms
0.801 0.199 0.000
M35.7 Hypermobility syndrome
0.797 0.203 0.000
G90-G99 Other disorders of the nervous system
0.789 0.211 0.000
D24 Benign neoplasm of breast
0.789 0.211 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.786 0.214 0.000
N64 Other disorders of breast
0.786 0.214 0.000
D12.7 Rectosigmoid junction
0.785 0.215 0.000
G57.6 Lesion of plantar nerve
0.785 0.215 0.000
C17.0 Duodenum
0.781 0.219 0.000
M65 Synovitis and tenosynovitis
0.781 0.219 0.000
E11 Non-insulin-dependent diabetes mellitus
0.781 0.219 0.000
C18.1 Appendix
0.777 0.223 0.000
D12.4 Descending colon
0.776 0.224 0.000
Chapter VII Diseases of the eye and adnexa
0.775 0.225 0.000
C16.0 Cardia
0.775 0.225 0.000
N17.9 Acute renal failure, unspecified
0.774 0.226 0.000
V10-V19 Pedal cyclist injured in transport accident
0.773 0.226 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.773 0.227 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.772 0.227 0.000
H71 Cholesteatoma of middle ear
0.772 0.228 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.772 0.228 0.000
M25 Other joint disorders, not elsewhere classified
0.771 0.229 0.000
C18.0 Caecum
0.770 0.230 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.770 0.230 0.000
M86-M90 Other osteopathies
0.768 0.232 0.000
C25 Malignant neoplasm of pancreas
0.767 0.232 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.767 0.233 0.000
Chapter V Mental and behavioural disorders
0.764 0.236 0.000
E50-E64 Other nutritional deficiencies
0.763 0.237 0.000
N32 Other disorders of bladder
0.761 0.239 0.000
N28.8 Other specified disorders of kidney and ureter
0.757 0.243 0.000
D10 Benign neoplasm of mouth and pharynx
0.757 0.243 0.000
M60-M63 Disorders of muscles
0.757 0.243 0.000
D23 Other benign neoplasms of skin
0.755 0.245 0.000
M67 Other disorders of synovium and tendon
0.753 0.247 0.000
E10.3 With ophthalmic complications
0.752 0.248 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.751 0.249 0.000
M94 Other disorders of cartilage
0.750 0.250 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.749 0.251 0.000
D11 Benign neoplasm of major salivary glands
0.747 0.253 0.000
D12.8 Rectum
0.746 0.254 0.000
M35.3 Polymyalgia rheumatica
0.745 0.255 0.000
Y44 Agents primarily affecting blood constituents
0.744 0.256 0.000
N05 Unspecified nephritic syndrome
0.744 0.256 0.000
Y45.0 Opioids and related analgesics
0.743 0.257 0.000
C17.9 Small intestine, unspecified
0.742 0.258 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.741 0.259 0.000
M22 Disorders of patella
0.740 0.260 0.000
E10.2 With renal complications
0.737 0.263 0.000
M79.0 Rheumatism, unspecified
0.736 0.264 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.736 0.264 0.000
D26 Other benign neoplasms of uterus
0.735 0.265 0.000
D68 Other coagulation defects
0.734 0.266 0.000
E20-E35 Disorders of other endocrine glands
0.731 0.269 0.000
C79.6 Secondary malignant neoplasm of ovary
0.730 0.270 0.000
M81.9 Osteoporosis, unspecified
0.729 0.271 0.000
M34.1 CR(E)ST syndrome
0.729 0.271 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.728 0.272 0.000
N10 Acute tubulo-interstitial nephritis
0.728 0.272 0.000
N64.5 Other signs and symptoms in breast
0.727 0.273 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.727 0.273 0.000
D32 Benign neoplasm of meninges
0.726 0.274 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.725 0.275 0.000
M82 Osteoporosis in diseases classified elsewhere
0.725 0.275 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.722 0.278 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.722 0.278 0.000
Chapter IX Diseases of the circulatory system
0.721 0.279 0.000
Q60-Q64 Congenital malformations of the urinary system
0.718 0.282 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.717 0.283 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.717 0.283 0.000
C21 Malignant neoplasm of anus and anal canal
0.717 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
Y45.1 Salicylates
0.710 0.289 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.709 0.290 0.000
D45 Polycythaemia vera
0.709 0.291 0.000
M21.1 Varus deformity, not elsewhere classified
0.709 0.291 0.000
C80 Malignant neoplasm without specification of site
0.709 0.291 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.708 0.292 0.000
Chapter XXII Codes for special purposes
0.708 0.292 0.000
M50-M54 Other dorsopathies
0.705 0.295 0.000
N13.4 Hydroureter
0.705 0.295 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
N03 Chronic nephritic syndrome
0.703 0.297 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.703 0.297 0.000
M34.9 Systemic sclerosis, unspecified
0.702 0.298 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.702 0.298 0.000
M35.8 Other specified systemic involvement of connective tissue
0.702 0.298 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.702 0.298 0.000
M35.5 Multifocal fibrosclerosis
0.702 0.298 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.702 0.298 0.000
M35.2 Behcet's disease
0.702 0.298 0.000
M35.1 Other overlap syndromes
0.702 0.298 0.000
D60-D64 Aplastic and other anaemias
0.701 0.299 0.000
C18.4 Transverse colon
0.701 0.299 0.000
M21.0 Valgus deformity, not elsewhere classified
0.700 0.300 0.000
C01 Malignant neoplasm of base of tongue
0.700 0.300 0.000
C15.8 Overlapping lesion of oesophagus
0.698 0.302 0.000
C15.4 Middle third of oesophagus
0.698 0.302 0.000
C15.3 Upper third of oesophagus
0.698 0.302 0.000
C15.2 Abdominal part of oesophagus
0.698 0.302 0.000
C15.1 Thoracic part of oesophagus
0.698 0.302 0.000
C15.0 Cervical part of oesophagus
0.698 0.302 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.698 0.302 0.000
M79.9 Soft tissue disorder, unspecified
0.698 0.302 0.000
C18.8 Overlapping lesion of colon
0.697 0.303 0.000
C18.5 Splenic flexure
0.697 0.303 0.000
X60-X84 Intentional self-harm
0.697 0.303 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.306 0.000
M79.1 Myalgia
0.692 0.308 0.000
E10.1 With ketoacidosis
0.692 0.308 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.691 0.309 0.000
M84 Disorders of continuity of bone
0.691 0.309 0.000
M21.4 Flat foot [pes planus] (acquired)
0.691 0.309 0.000
Y52.1 Calcium-channel blockers
0.690 0.310 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.690 0.310 0.000
N02 Recurrent and persistent haematuria
0.690 0.310 0.000
M66 Spontaneous rupture of synovium and tendon
0.690 0.310 0.000
H74 Other disorders of middle ear and mastoid
0.689 0.311 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.688 0.311 0.000
M24.6 Ankylosis of joint
0.687 0.313 0.000
D18 Haemangioma and lymphangioma, any site
0.686 0.314 0.000
C79.2 Secondary malignant neoplasm of skin
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
M80 Osteoporosis with pathological fracture
0.683 0.317 0.000
D50-D53 Nutritional anaemias
0.683 0.317 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.683 0.317 0.000
G93 Other disorders of brain
0.680 0.320 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.679 0.321 0.000
N15 Other renal tubulo-interstitial diseases
0.679 0.321 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.679 0.321 0.000
N11 Chronic tubulo-interstitial nephritis
0.679 0.321 0.000
N13.6 Pyonephrosis
0.679 0.321 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.679 0.321 0.000
E40-E46 Malnutrition
0.679 0.321 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.321 0.000
Y10-Y34 Event of undetermined intent
0.679 0.321 0.000
Y00-Y09 Assault
0.679 0.321 0.000
X85-X99 Assault
0.679 0.321 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.679 0.321 0.000
X50-X57 Overexertion, travel and privation
0.679 0.321 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.679 0.321 0.000
X30-X39 Exposure to forces of nature
0.679 0.321 0.000
X20-X29 Contact with venomous animals and plants
0.679 0.321 0.000
X10-X19 Contact with heat and hot substances
0.679 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.321 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.321 0.000
W75-W84 Other accidental threats to breathing
0.679 0.321 0.000
W65-W74 Accidental drowning and submersion
0.679 0.321 0.000
W50-W64 Exposure to animate mechanical forces
0.679 0.321 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.321 0.000
V95-V97 Air and space transport accidents
0.679 0.321 0.000
V90-V94 Water transport accidents
0.679 0.321 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.321 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.321 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.321 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.321 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.321 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.321 0.000
H72 Perforation of tympanic membrane
0.678 0.322 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.325 0.000
M72 Fibroblastic disorders
0.674 0.326 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.672 0.328 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.671 0.329 0.000
E13 Other specified diabetes mellitus
0.671 0.329 0.000
E12 Malnutrition-related diabetes mellitus
0.671 0.329 0.000
D36 Benign neoplasm of other and unspecified sites
0.670 0.330 0.000
W20-W49 Exposure to inanimate mechanical forces
0.669 0.331 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
C16.8 Overlapping lesion of stomach
0.667 0.333 0.000
C16.6 Greater curvature of stomach, unspecified
0.667 0.333 0.000
C16.5 Lesser curvature of stomach, unspecified
0.667 0.333 0.000
C16.4 Pylorus
0.667 0.333 0.000
C16.3 Pyloric antrum
0.667 0.333 0.000
C16.2 Body of stomach
0.667 0.333 0.000
C16.1 Fundus of stomach
0.667 0.333 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.667 0.333 0.000
Y40 Systemic antibiotics
0.667 0.333 0.000
D31 Benign neoplasm of eye and adnexa
0.667 0.333 0.000
D30 Benign neoplasm of urinary organs
0.667 0.333 0.000
D29 Benign neoplasm of male genital organs
0.667 0.333 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.667 0.333 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.667 0.333 0.000
D19 Benign neoplasm of mesothelial tissue
0.667 0.333 0.000
D16 Benign neoplasm of bone and articular cartilage
0.667 0.333 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.667 0.333 0.000
D34 Benign neoplasm of thyroid gland
0.667 0.333 0.000
I30-I52 Other forms of heart disease
0.667 0.333 0.000
H30-H36 Disorders of choroid and retina
0.666 0.334 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.666 0.334 0.000
N32.3 Diverticulum of bladder
0.665 0.335 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.664 0.336 0.000
N27 Small kidney of unknown cause
0.664 0.336 0.000
N25 Disorders resulting from impaired renal tubular function
0.664 0.336 0.000
N26 Unspecified contracted kidney
0.664 0.336 0.000
M31 Other necrotising vasculopathies
0.663 0.337 0.000
N99.2 Postprocedural adhesions of vagina
0.663 0.337 0.000
E06 Thyroiditis
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.663 0.337 0.000
N30 Cystitis
0.662 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.661 0.338 0.000
Y58 Bacterial vaccines
0.661 0.338 0.000
Y57 Other and unspecified drugs and medicaments
0.661 0.338 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.338 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.338 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.661 0.338 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.338 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.661 0.338 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.661 0.338 0.000
Y48 Anaesthetics and therapeutic gases
0.661 0.338 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.661 0.338 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.661 0.338 0.000
N04 Nephrotic syndrome
0.661 0.339 0.000
E11.3 With ophthalmic complications
0.661 0.339 0.000
D12.9 Anus and anal canal
0.660 0.340 0.000
D12.1 Appendix
0.660 0.340 0.000
E11.2 With renal complications
0.660 0.340 0.000
D23.7 Skin of lower limb, including hip
0.659 0.341 0.000
M81.98 Osteoporosis, unspecified (Other)
0.658 0.342 0.000
N99.0 Postprocedural renal failure
0.658 0.342 0.000
E10.8 With unspecified complications
0.658 0.342 0.000
E10.7 With multiple complications
0.658 0.342 0.000
E10.6 With other specified complications
0.658 0.342 0.000
E10.5 With peripheral circulatory complications
0.658 0.342 0.000
E10.0 With coma
0.658 0.342 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.657 0.342 0.000
Y88 Sequelae of surgical and medical care as external cause
0.657 0.343 0.000
M24.2 Disorder of ligament
0.657 0.343 0.000
M20 Acquired deformities of fingers and toes
0.657 0.343 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.656 0.344 0.000
C18.3 Hepatic flexure
0.656 0.344 0.000
N60 Benign mammary dysplasia
0.656 0.344 0.000
M83 Adult osteomalacia
0.656 0.344 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.655 0.345 0.000
C18.6 Descending colon
0.655 0.345 0.000
M85 Other disorders of bone density and structure
0.654 0.346 0.000
D05 Carcinoma in situ of breast
0.651 0.349 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.651 0.349 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.650 0.350 0.000
N06 Isolated proteinuria with specified morphological lesion
0.650 0.350 0.000
N01 Rapidly progressive nephritic syndrome
0.650 0.350 0.000
N00 Acute nephritic syndrome
0.650 0.350 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.650 0.350 0.000
M24.1 Other articular cartilage disorders
0.649 0.351 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.648 0.352 0.000
M94.8 Other specified disorders of cartilage
0.648 0.352 0.000
N32.8 Other specified disorders of bladder
0.648 0.352 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.648 0.352 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.647 0.352 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.647 0.352 0.000
M65.3 Trigger finger
0.647 0.352 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.646 0.353 0.000
M71 Other bursopathies
0.645 0.355 0.000
E11.5 With peripheral circulatory complications
0.645 0.355 0.000
N19 Unspecified renal failure
0.645 0.355 0.000
C17.8 Overlapping lesion of small intestine
0.644 0.355 0.000
C17.3 Meckel's diverticulum
0.644 0.355 0.000
C17.2 Ileum
0.644 0.355 0.000
C17.1 Jejunum
0.644 0.355 0.000
D46 Myelodysplastic syndromes
0.644 0.356 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.644 0.356 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.643 0.357 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.643 0.357 0.000
Y85 Sequelae of transport accidents
0.643 0.357 0.000
M67.8 Other specified disorders of synovium and tendon
0.642 0.358 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.642 0.358 0.000
D80-D89 Certain disorders involving the immune mechanism
0.641 0.359 0.000
M76 Enthesopathies of lower limb, excluding foot
0.641 0.359 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.641 0.359 0.000
M21.3 Wrist or foot drop (acquired)
0.641 0.359 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.640 0.360 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.640 0.360 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.640 0.360 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.640 0.360 0.000
D68.2 Hereditary deficiency of other clotting factors
0.640 0.360 0.000
Q80-Q89 Other congenital malformations
0.639 0.361 0.000
D10.3 Other and unspecified parts of mouth
0.639 0.361 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.639 0.361 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.638 0.362 0.000
D12.6 Colon, unspecified
0.637 0.363 0.000
D55-D59 Haemolytic anaemias
0.637 0.363 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.636 0.364 0.000
M21.9 Acquired deformity of limb, unspecified
0.636 0.364 0.000
M21.8 Other specified acquired deformities of limbs
0.636 0.364 0.000
M21.7 Unequal limb length (acquired)
0.636 0.364 0.000
M21.6 Other acquired deformities of ankle and foot
0.636 0.364 0.000
M21.2 Flexion deformity
0.636 0.364 0.000
Q50-Q56 Congenital malformations of genital organs
0.634 0.366 0.000
M25.4 Effusion of joint
0.633 0.367 0.000
M89 Other disorders of bone
0.632 0.368 0.000
H66 Suppurative and unspecified otitis media
0.631 0.369 0.000
E10.4 With neurological complications
0.630 0.370 0.000
N28.0 Ischaemia and infarction of kidney
0.629 0.371 0.000
M40-M43 Deforming dorsopathies
0.629 0.371 0.000
G91 Hydrocephalus
0.629 0.371 0.000
D23.3 Skin of other and unspecified parts of face
0.628 0.372 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.628 0.372 0.000
N05.9 Unspecified
0.627 0.373 0.000
M79.5 Residual foreign body in soft tissue
0.627 0.373 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.627 0.373 0.000
M79.3 Panniculitis, unspecified
0.627 0.373 0.000
M79.2 Neuralgia and neuritis, unspecified
0.627 0.373 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.627 0.373 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.626 0.374 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.626 0.374 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.626 0.374 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.626 0.374 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.626 0.374 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.625 0.375 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.625 0.375 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.623 0.377 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.623 0.377 0.000
Q35-Q37 Cleft lip and cleft palate
0.623 0.377 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.623 0.377 0.000
Q00-Q07 Congenital malformations of the nervous system
0.623 0.377 0.000
H80-H83 Diseases of inner ear
0.622 0.378 0.000
E05.9 Thyrotoxicosis, unspecified
0.622 0.378 0.000
W00-W19 Falls
0.621 0.379 0.000
M34.8 Other forms of systemic sclerosis
0.621 0.379 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.621 0.379 0.000
M34.0 Progressive systemic sclerosis
0.621 0.379 0.000
F80-F89 Disorders of psychological development
0.620 0.380 0.000
G59.0 Diabetic mononeuropathy
0.620 0.380 0.000
Chapter XI Diseases of the digestive system
0.619 0.381 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.618 0.382 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.617 0.383 0.000
C13 Malignant neoplasm of hypopharynx
0.617 0.383 0.000
C11 Malignant neoplasm of nasopharynx
0.617 0.383 0.000
C10 Malignant neoplasm of oropharynx
0.617 0.383 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.617 0.383 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.617 0.383 0.000
C05 Malignant neoplasm of palate
0.617 0.383 0.000
C04 Malignant neoplasm of floor of mouth
0.617 0.383 0.000
C03 Malignant neoplasm of gum
0.617 0.383 0.000
C00 Malignant neoplasm of lip
0.617 0.383 0.000
C12 Malignant neoplasm of pyriform sinus
0.617 0.383 0.000
C07 Malignant neoplasm of parotid gland
0.617 0.383 0.000
Y44.2 Anticoagulants
0.616 0.384 0.000
D11.0 Parotid gland
0.616 0.384 0.000
E55 Vitamin D deficiency
0.616 0.384 0.000
M22.3 Other derangements of patella
0.616 0.384 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.615 0.385 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.615 0.385 0.000
H36 Retinal disorders in diseases classified elsewhere
0.615 0.385 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.614 0.386 0.000
Y45.8 Other analgesics and antipyretics
0.614 0.386 0.000
Y45.5 4-Aminophenol derivatives
0.614 0.386 0.000
Y45.4 Antirheumatics
0.614 0.386 0.000
Y45.2 Propionic acid derivatives
0.614 0.386 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.613 0.387 0.000
C66 Malignant neoplasm of ureter
0.613 0.387 0.000
C65 Malignant neoplasm of renal pelvis
0.613 0.387 0.000
C67 Malignant neoplasm of bladder
0.613 0.387 0.000
M93 Other osteochondropathies
0.612 0.388 0.000
M92 Other juvenile osteochondrosis
0.612 0.388 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.612 0.388 0.000
Q63 Other congenital malformations of kidney
0.612 0.388 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.612 0.388 0.000
K50-K52 Noninfective enteritis and colitis
0.611 0.389 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.611 0.389 0.000
C73 Malignant neoplasm of thyroid gland
0.610 0.390 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.610 0.390 0.000
N99.5 Malfunction of external stoma of urinary tract
0.610 0.390 0.000
N99.1 Postprocedural urethral stricture
0.610 0.390 0.000
M79.7 Fibromyalgia
0.609 0.391 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.609 0.391 0.000
D69 Purpura and other haemorrhagic conditions
0.609 0.391 0.000
H10-H13 Disorders of conjunctiva
0.608 0.392 0.000
H90-H95 Other disorders of ear
0.608 0.392 0.000
D09 Carcinoma in situ of other and unspecified sites
0.608 0.392 0.000
N18 Chronic renal failure
0.608 0.392 0.000
M24.9 Joint derangement, unspecified
0.607 0.393 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.607 0.393 0.000
M24.7 Protrusio acetabuli
0.607 0.393 0.000
M24.5 Contracture of joint
0.607 0.393 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.607 0.393 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.607 0.393 0.000
M24.0 Loose body in joint
0.607 0.393 0.000
K51 Ulcerative colitis
0.607 0.393 0.000
D23.0 Skin of lip
0.607 0.393 0.000
Y43 Primarily systemic agents
0.605 0.394 0.000
H52 Disorders of refraction and accommodation
0.604 0.396 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.604 0.396 0.000
C09 Malignant neoplasm of tonsil
0.603 0.396 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.603 0.397 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.603 0.397 0.000
G51 Facial nerve disorders
0.603 0.397 0.000
G58 Other mononeuropathies
0.603 0.397 0.000
H73 Other disorders of tympanic membrane
0.603 0.397 0.000
G30-G32 Other degenerative diseases of the nervous system
0.602 0.398 0.000
N36 Other disorders of urethra
0.602 0.398 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.602 0.398 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.602 0.398 0.000
H70 Mastoiditis and related conditions
0.602 0.398 0.000
H69 Other disorders of Eustachian tube
0.602 0.398 0.000
H68 Eustachian salpingitis and obstruction
0.602 0.398 0.000
H67 Otitis media in diseases classified elsewhere
0.602 0.398 0.000
E11.4 With neurological complications
0.602 0.398 0.000
E07 Other disorders of thyroid
0.601 0.399 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.600 0.400 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.599 0.401 0.000
M79.88 Other specified soft tissue disorders (Other)
0.599 0.401 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.599 0.401 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.599 0.401 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.599 0.401 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.599 0.401 0.000
N30.2 Other chronic cystitis
0.599 0.401 0.000
M25.3 Other instability of joint
0.598 0.402 0.000
N32.0 Bladder-neck obstruction
0.598 0.402 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.597 0.402 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.596 0.403 0.000
I45 Other conduction disorders
0.596 0.404 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.596 0.404 0.000
G52 Disorders of other cranial nerves
0.596 0.404 0.000
D26.1 Corpus uteri
0.595 0.405 0.000
I73 Other peripheral vascular diseases
0.595 0.405 0.000
M94.2 Chondromalacia
0.594 0.406 0.000
G50 Disorders of trigeminal nerve
0.593 0.407 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.592 0.408 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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