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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12972378
log Bayes Factor = 13.8299
Chromosome 19   position 5,649,716  (GRCh37) Explore rs12972378 on Ensembl!
Variant rs12972378 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
N17-N19 Renal failure
0.990 0.010 0.000
M45-M49 Spondylopathies
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.976 0.024 0.000
Chapter XI Diseases of the digestive system
0.976 0.024 0.000
K55-K64 Other diseases of intestines
0.973 0.027 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.972 0.028 0.000
M47 Spondylosis
0.971 0.029 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.970 0.030 0.000
K62 Other diseases of anus and rectum
0.969 0.031 0.000
K62.5 Haemorrhage of anus and rectum
0.968 0.032 0.000
N18 Chronic renal failure
0.967 0.033 0.000
C60-C63 Malignant neoplasms of male genital organs
0.966 0.034 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.966 0.034 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.962 0.038 0.000
Chapter X Diseases of the respiratory system
0.960 0.040 0.000
G40-G47 Episodic and paroxysmal disorders
0.955 0.045 0.000
C15-C26 Malignant neoplasms of digestive organs
0.951 0.049 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.950 0.050 0.000
Chapter VII Diseases of the eye and adnexa
0.947 0.053 0.000
C61 Malignant neoplasm of prostate
0.944 0.056 0.000
N18.9 Chronic renal failure, unspecified
0.942 0.058 0.000
K63 Other diseases of intestine
0.939 0.061 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.935 0.065 0.000
M40-M43 Deforming dorsopathies
0.932 0.068 0.000
K62.8 Other specified diseases of anus and rectum
0.931 0.069 0.000
Chapter XX External causes of morbidity and mortality
0.930 0.070 0.000
G40 Epilepsy
0.929 0.071 0.000
K63.5 Polyp of colon
0.928 0.072 0.000
C64-C68 Malignant neoplasms of urinary tract
0.926 0.074 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.925 0.075 0.000
G90-G99 Other disorders of the nervous system
0.924 0.076 0.000
K70-K77 Diseases of liver
0.922 0.078 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.916 0.084 0.000
M47.8 Other spondylosis
0.914 0.086 0.000
N72 Inflammatory disease of cervix uteri
0.911 0.089 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.907 0.093 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.905 0.095 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.904 0.096 0.000
M47.9 Spondylosis, unspecified
0.903 0.097 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.900 0.100 0.000
M43 Other deforming dorsopathies
0.897 0.103 0.000
L60-L75 Disorders of skin appendages
0.893 0.107 0.000
S90-S99 Injuries to the ankle and foot
0.884 0.116 0.000
Chapter VIII Diseases of the ear and mastoid process
0.882 0.118 0.000
L20-L30 Dermatitis and eczema
0.881 0.119 0.000
C15 Malignant neoplasm of oesophagus
0.881 0.119 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.872 0.128 0.000
M43.1 Spondylolisthesis
0.872 0.128 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.870 0.130 0.000
C18 Malignant neoplasm of colon
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.863 0.137 0.000
N19 Unspecified renal failure
0.862 0.138 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.859 0.141 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.857 0.143 0.000
N18.0 End-stage renal disease
0.852 0.148 0.000
C67 Malignant neoplasm of bladder
0.852 0.148 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.848 0.152 0.000
N40-N51 Diseases of male genital organs
0.848 0.152 0.000
L50-L54 Urticaria and erythema
0.848 0.152 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.847 0.153 0.000
M46 Other inflammatory spondylopathies
0.846 0.154 0.000
J00-J06 Acute upper respiratory infections
0.845 0.155 0.000
C77.2 Intra-abdominal lymph nodes
0.840 0.160 0.000
M47.82 Other spondylosis (Cervical region)
0.838 0.162 0.000
N48 Other disorders of penis
0.835 0.165 0.000
J30-J39 Other diseases of upper respiratory tract
0.835 0.165 0.000
N70 Salpingitis and oophoritis
0.834 0.166 0.000
N99-N99 Other disorders of the genitourinary system
0.834 0.166 0.000
H55-H59 Other disorders of eye and adnexa
0.831 0.169 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.829 0.171 0.000
N76 Other inflammation of vagina and vulva
0.828 0.172 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.826 0.174 0.000
C77.9 Lymph node, unspecified
0.825 0.175 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.823 0.177 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.820 0.180 0.000
G62 Other polyneuropathies
0.817 0.183 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.816 0.184 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.814 0.186 0.000
K50-K52 Noninfective enteritis and colitis
0.813 0.187 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.811 0.189 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.810 0.190 0.000
T90 Sequelae of injuries of head
0.809 0.191 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.809 0.191 0.000
N17 Acute renal failure
0.809 0.191 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.809 0.191 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.809 0.191 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
G40.9 Epilepsy, unspecified
0.807 0.193 0.000
M86-M90 Other osteopathies
0.806 0.194 0.000
K76 Other diseases of liver
0.805 0.195 0.000
M50-M54 Other dorsopathies
0.805 0.195 0.000
T82.1 Mechanical complication of cardiac electronic device
0.804 0.196 0.000
T66-T78 Other and unspecified effects of external causes
0.803 0.197 0.000
S92 Fracture of foot, except ankle
0.801 0.199 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.801 0.199 0.000
M47.86 Other spondylosis (Lumbar region)
0.800 0.200 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.799 0.201 0.000
K65-K67 Diseases of peritoneum
0.798 0.202 0.000
J20-J22 Other acute lower respiratory infections
0.798 0.202 0.000
H25-H28 Disorders of lens
0.798 0.202 0.000
N81 Female genital prolapse
0.797 0.203 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.797 0.203 0.000
G47 Sleep disorders
0.795 0.205 0.000
G20-G26 Extrapyramidal and movement disorders
0.794 0.206 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.792 0.208 0.000
L30 Other dermatitis
0.792 0.208 0.000
H53-H54 Visual disturbances and blindness
0.790 0.210 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
S20-S29 Injuries to the thorax
0.787 0.213 0.000
C16 Malignant neoplasm of stomach
0.786 0.214 0.000
H10-H13 Disorders of conjunctiva
0.786 0.214 0.000
D46 Myelodysplastic syndromes
0.786 0.214 0.000
M47.2 Other spondylosis with radiculopathy
0.785 0.215 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.784 0.216 0.000
H43-H45 Disorders of vitreous body and globe
0.783 0.217 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.781 0.219 0.000
K63.1 Perforation of intestine (nontraumatic)
0.779 0.221 0.000
Chapter XXI Factors influencing health status and contact with health services
0.779 0.221 0.000
S70-S79 Injuries to the hip and thigh
0.779 0.221 0.000
L72.0 Epidermal cyst
0.778 0.222 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.775 0.225 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.774 0.226 0.000
C67.9 Bladder, unspecified
0.773 0.227 0.000
K58 Irritable bowel syndrome
0.773 0.227 0.000
K59 Other functional intestinal disorders
0.773 0.227 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.772 0.228 0.000
C23 Malignant neoplasm of gallbladder
0.772 0.228 0.000
S80-S89 Injuries to the knee and lower leg
0.772 0.228 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.771 0.229 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.769 0.231 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.769 0.231 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.768 0.232 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.767 0.233 0.000
K74 Fibrosis and cirrhosis of liver
0.767 0.233 0.000
Y43 Primarily systemic agents
0.767 0.233 0.000
N48.6 Balanitis xerotica obliterans
0.767 0.233 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.766 0.234 0.000
N18.5 Chronic kidney disease, stage 5
0.764 0.236 0.000
T86 Failure and rejection of transplanted organs and tissues
0.764 0.236 0.000
D69 Purpura and other haemorrhagic conditions
0.760 0.240 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.759 0.240 0.000
T43.2 Other and unspecified antidepressants
0.759 0.241 0.000
N71 Inflammatory disease of uterus, except cervix
0.758 0.242 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.756 0.244 0.000
S60-S69 Injuries to the wrist and hand
0.755 0.245 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.755 0.245 0.000
C85.1 B-cell lymphoma, unspecified
0.755 0.245 0.000
D50-D53 Nutritional anaemias
0.754 0.246 0.000
C15.5 Lower third of oesophagus
0.753 0.247 0.000
H65-H75 Diseases of middle ear and mastoid
0.752 0.248 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.752 0.248 0.000
D48.1 Connective and other soft tissue
0.750 0.250 0.000
N48.4 Impotence of organic origin
0.750 0.250 0.000
Z51 Other medical care
0.749 0.251 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.748 0.252 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.747 0.253 0.000
K75 Other inflammatory liver diseases
0.746 0.254 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.744 0.256 0.000
G91 Hydrocephalus
0.743 0.257 0.000
Z51.1 Chemotherapy session for neoplasm
0.742 0.258 0.000
N25-N29 Other disorders of kidney and ureter
0.741 0.259 0.000
K50 Crohn's disease [regional enteritis]
0.740 0.260 0.000
N10-N16 Renal tubulo-interstitial diseases
0.739 0.261 0.000
J40-J47 Chronic lower respiratory diseases
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.738 0.262 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.738 0.262 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.738 0.262 0.000
C81 Hodgkin's disease
0.737 0.263 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.737 0.263 0.000
L53 Other erythematous conditions
0.737 0.263 0.000
C91 Lymphoid leukaemia
0.736 0.263 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.264 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.736 0.264 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.736 0.264 0.000
N81.4 Uterovaginal prolapse, unspecified
0.735 0.265 0.000
T42.4 Benzodiazepines
0.735 0.265 0.000
G51 Facial nerve disorders
0.735 0.265 0.000
M48 Other spondylopathies
0.735 0.265 0.000
C51-C58 Malignant neoplasms of female genital organs
0.733 0.267 0.000
N81.2 Incomplete uterovaginal prolapse
0.733 0.267 0.000
N70.1 Chronic salpingitis and oophoritis
0.731 0.269 0.000
C77.8 Lymph nodes of multiple regions
0.731 0.269 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.729 0.271 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.729 0.271 0.000
C77.5 Intrapelvic lymph nodes
0.728 0.271 0.000
L30.9 Dermatitis, unspecified
0.728 0.272 0.000
S92.3 Fracture of metatarsal bone
0.728 0.272 0.000
C15.9 Oesophagus, unspecified
0.727 0.273 0.000
N76.0 Acute vaginitis
0.726 0.274 0.000
C77.0 Lymph nodes of head, face and neck
0.726 0.274 0.000
S00-S09 Injuries to the head
0.724 0.275 0.000
M54 Dorsalgia
0.724 0.276 0.000
Z51.0 Radiotherapy session
0.723 0.277 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.722 0.278 0.000
J90-J94 Other diseases of pleura
0.722 0.278 0.000
W00-W19 Falls
0.722 0.278 0.000
M91-M94 Chondropathies
0.721 0.278 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.721 0.279 0.000
G62.9 Polyneuropathy, unspecified
0.721 0.279 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.721 0.279 0.000
C15.4 Middle third of oesophagus
0.721 0.279 0.000
L71 Rosacea
0.720 0.280 0.000
G93 Other disorders of brain
0.720 0.280 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.719 0.281 0.000
T93 Sequelae of injuries of lower limb
0.719 0.281 0.000
W20-W49 Exposure to inanimate mechanical forces
0.719 0.281 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M45 Ankylosing spondylitis
0.716 0.284 0.000
G61 Inflammatory polyneuropathy
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
N97 Female infertility
0.716 0.284 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.716 0.284 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.716 0.284 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.716 0.284 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.715 0.285 0.000
N48.8 Other specified disorders of penis
0.715 0.285 0.000
H25 Senile cataract
0.715 0.285 0.000
H80-H83 Diseases of inner ear
0.714 0.285 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.714 0.286 0.000
C18.9 Colon, unspecified
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.714 0.286 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.714 0.286 0.000
D00-D09 In situ neoplasms
0.713 0.287 0.000
M65-M68 Disorders of synovium and tendon
0.712 0.288 0.000
K76.8 Other specified diseases of liver
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.711 0.289 0.000
K70 Alcoholic liver disease
0.710 0.289 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.708 0.291 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.707 0.293 0.000
J02 Acute pharyngitis
0.706 0.294 0.000
M49 Spondylopathies in diseases classified elsewhere
0.706 0.294 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.705 0.295 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
K35-K38 Diseases of appendix
0.703 0.297 0.000
G47.9 Sleep disorder, unspecified
0.702 0.298 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
C80 Malignant neoplasm without specification of site
0.700 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.300 0.000
N50 Other disorders of male genital organs
0.700 0.300 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.699 0.301 0.000
Y43.3 Other antineoplastic drugs
0.699 0.301 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.302 0.000
C18.2 Ascending colon
0.698 0.302 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.698 0.302 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.697 0.303 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.697 0.303 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.697 0.303 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.697 0.303 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.697 0.303 0.000
D70 Agranulocytosis
0.697 0.303 0.000
K62.4 Stenosis of anus and rectum
0.696 0.304 0.000
M47.1 Other spondylosis with myelopathy
0.696 0.304 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.696 0.304 0.000
K62.6 Ulcer of anus and rectum
0.696 0.304 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.696 0.304 0.000
D69.6 Thrombocytopenia, unspecified
0.696 0.304 0.000
T40.2 Other opioids
0.695 0.305 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.695 0.305 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.694 0.305 0.000
K62.2 Anal prolapse
0.694 0.305 0.000
N18.8 Other chronic renal failure
0.693 0.307 0.000
N18.1 Chronic kidney disease, stage 1
0.693 0.307 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.693 0.307 0.000
C60 Malignant neoplasm of penis
0.693 0.307 0.000
Z49 Care involving dialysis
0.693 0.307 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.693 0.307 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.693 0.307 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.693 0.307 0.000
T82.3 Mechanical complication of other vascular grafts
0.693 0.307 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.693 0.307 0.000
N18.4 Chronic kidney disease, stage 4
0.692 0.307 0.000
D43.2 Brain, unspecified
0.692 0.308 0.000
J30 Vasomotor and allergic rhinitis
0.691 0.309 0.000
M05-M14 Inflammatory polyarthropathies
0.691 0.309 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.691 0.309 0.000
S42 Fracture of shoulder and upper arm
0.690 0.310 0.000
L10-L14 Bullous disorders
0.690 0.310 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.687 0.313 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.687 0.313 0.000
C18.5 Splenic flexure
0.686 0.314 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.686 0.314 0.000
L29 Pruritus
0.686 0.314 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.686 0.314 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.685 0.315 0.000
G41 Status epilepticus
0.685 0.315 0.000
J44 Other chronic obstructive pulmonary disease
0.685 0.315 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.684 0.316 0.000
G95 Other diseases of spinal cord
0.684 0.316 0.000
N80 Endometriosis
0.683 0.317 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.682 0.317 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.682 0.318 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.682 0.318 0.000
C21 Malignant neoplasm of anus and anal canal
0.682 0.318 0.000
C17 Malignant neoplasm of small intestine
0.682 0.318 0.000
D48.0 Bone and articular cartilage
0.682 0.318 0.000
J22 Unspecified acute lower respiratory infection
0.682 0.318 0.000
D48.6 Breast
0.682 0.318 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.682 0.318 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.681 0.318 0.000
C95 Leukaemia of unspecified cell type
0.681 0.318 0.000
C94 Other leukaemias of specified cell type
0.681 0.318 0.000
C93 Monocytic leukaemia
0.681 0.318 0.000
C88 Malignant immunoproliferative diseases
0.681 0.318 0.000
C86 Other specified types of T/NK-cell lymphoma
0.681 0.318 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.681 0.318 0.000
G51.0 Bell's palsy
0.680 0.320 0.000
C25 Malignant neoplasm of pancreas
0.680 0.320 0.000
N17.9 Acute renal failure, unspecified
0.679 0.321 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.679 0.321 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.678 0.322 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.677 0.323 0.000
C18.4 Transverse colon
0.676 0.324 0.000
S92.30 Fracture of metatarsal bone (closed)
0.676 0.324 0.000
D51 Vitamin B12 deficiency anaemia
0.676 0.324 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.674 0.326 0.000
K63.4 Enteroptosis
0.674 0.326 0.000
K63.0 Abscess of intestine
0.674 0.326 0.000
C67.2 Lateral wall of bladder
0.673 0.327 0.000
L27 Dermatitis due to substances taken internally
0.672 0.328 0.000
G44 Other headache syndromes
0.672 0.328 0.000
Z48 Other surgical follow-up care
0.671 0.328 0.000
C62 Malignant neoplasm of testis
0.671 0.329 0.000
K57 Diverticular disease of intestine
0.671 0.329 0.000
L50 Urticaria
0.670 0.329 0.000
H11 Other disorders of conjunctiva
0.670 0.330 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.669 0.331 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.669 0.331 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.669 0.331 0.000
M42 Spinal osteochondrosis
0.668 0.331 0.000
M40 Kyphosis and lordosis
0.668 0.331 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.667 0.333 0.000
N48.9 Disorder of penis, unspecified
0.667 0.333 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.666 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.666 0.333 0.000
Y10-Y34 Event of undetermined intent
0.666 0.333 0.000
Y00-Y09 Assault
0.666 0.333 0.000
X85-X99 Assault
0.666 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.666 0.333 0.000
X50-X57 Overexertion, travel and privation
0.666 0.333 0.000
X30-X39 Exposure to forces of nature
0.666 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.666 0.333 0.000
X10-X19 Contact with heat and hot substances
0.666 0.333 0.000
X00-X09 Exposure to smoke, fire and flames
0.666 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.666 0.333 0.000
W75-W84 Other accidental threats to breathing
0.666 0.333 0.000
W65-W74 Accidental drowning and submersion
0.666 0.333 0.000
W50-W64 Exposure to animate mechanical forces
0.666 0.333 0.000
V98-V99 Other and unspecified transport accidents
0.666 0.333 0.000
V95-V97 Air and space transport accidents
0.666 0.333 0.000
V90-V94 Water transport accidents
0.666 0.333 0.000
V80-V89 Other land transport accidents
0.666 0.333 0.000
V70-V79 Bus occupant injured in transport accident
0.666 0.333 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.666 0.333 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.666 0.333 0.000
V40-V49 Car occupant injured in transport accident
0.666 0.333 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.666 0.333 0.000
V20-V29 Motorcycle rider injured in transport accident
0.666 0.333 0.000
V01-V09 Pedestrian injured in transport accident
0.666 0.333 0.000
G40.8 Other epilepsy
0.666 0.334 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.666 0.334 0.000
G40.5 Special epileptic syndromes
0.666 0.334 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.666 0.334 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.666 0.334 0.000
G62.8 Other specified polyneuropathies
0.666 0.334 0.000
H43 Disorders of vitreous body
0.665 0.335 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.665 0.335 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.664 0.336 0.000
C66 Malignant neoplasm of ureter
0.664 0.336 0.000
C65 Malignant neoplasm of renal pelvis
0.664 0.336 0.000
G20 Parkinson's disease
0.664 0.336 0.000
H90-H95 Other disorders of ear
0.663 0.337 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.663 0.337 0.000
T78 Adverse effects, not elsewhere classified
0.662 0.338 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G96 Other disorders of central nervous system
0.662 0.338 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.662 0.338 0.000
G90 Disorders of autonomic nervous system
0.662 0.338 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G92 Toxic encephalopathy
0.662 0.338 0.000
Q60-Q64 Congenital malformations of the urinary system
0.662 0.338 0.000
K77 Liver disorders in diseases classified elsewhere
0.661 0.339 0.000
K73 Chronic hepatitis, not elsewhere classified
0.661 0.339 0.000
K71 Toxic liver disease
0.661 0.339 0.000
K76.6 Portal hypertension
0.659 0.341 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.659 0.341 0.000
M47.89 Other spondylosis (Site unspecified)
0.658 0.342 0.000
J37 Chronic laryngitis and laryngotracheitis
0.658 0.342 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.657 0.343 0.000
L53.9 Erythematous condition, unspecified
0.657 0.343 0.000
D55-D59 Haemolytic anaemias
0.657 0.343 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.657 0.343 0.000
K72 Hepatic failure, not elsewhere classified
0.656 0.344 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.655 0.345 0.000
J00 Acute nasopharyngitis [common cold]
0.655 0.345 0.000
Z46 Fitting and adjustment of other devices
0.655 0.345 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.655 0.345 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.655 0.345 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.655 0.345 0.000
M47.84 Other spondylosis (Thoracic region)
0.655 0.345 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.655 0.345 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.655 0.345 0.000
C16.0 Cardia
0.655 0.345 0.000
N85.0 Endometrial glandular hyperplasia
0.654 0.346 0.000
C18.6 Descending colon
0.653 0.347 0.000
C01 Malignant neoplasm of base of tongue
0.653 0.347 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.652 0.348 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.651 0.349 0.000
T51 Toxic effect of alcohol
0.651 0.349 0.000
J35 Chronic diseases of tonsils and adenoids
0.651 0.349 0.000
J60-J70 Lung diseases due to external agents
0.650 0.350 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.650 0.350 0.000
S50-S59 Injuries to the elbow and forearm
0.650 0.350 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.649 0.350 0.000
T92 Sequelae of injuries of upper limb
0.649 0.350 0.000
G60 Hereditary and idiopathic neuropathy
0.649 0.351 0.000
G64 Other disorders of peripheral nervous system
0.649 0.351 0.000
D39.1 Ovary
0.649 0.351 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.649 0.351 0.000
H55 Nystagmus and other irregular eye movements
0.649 0.351 0.000
T98 Sequelae of other and unspecified effects of external causes
0.648 0.352 0.000
T95 Sequelae of burns, corrosions and frostbite
0.648 0.352 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.648 0.352 0.000
T91 Sequelae of injuries of neck and trunk
0.648 0.352 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.648 0.352 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.648 0.352 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.648 0.352 0.000
N18.2 Chronic kidney disease, stage 2
0.648 0.352 0.000
N48.2 Other inflammatory disorders of penis
0.648 0.352 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.648 0.352 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.648 0.352 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.648 0.352 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.648 0.352 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.648 0.352 0.000
H71 Cholesteatoma of middle ear
0.647 0.353 0.000
N86 Erosion and ectropion of cervix uteri
0.647 0.353 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.647 0.353 0.000
C18.3 Hepatic flexure
0.646 0.354 0.000
C77.3 Axillary and upper limb lymph nodes
0.646 0.354 0.000
T43.9 Psychotropic drug, unspecified
0.645 0.355 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.645 0.355 0.000
T43.6 Psychostimulants with abuse potential
0.645 0.355 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.645 0.355 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.645 0.355 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.645 0.355 0.000
K63.3 Ulcer of intestine
0.645 0.355 0.000
D75 Other diseases of blood and blood-forming organs
0.645 0.355 0.000
M43.9 Deforming dorsopathy, unspecified
0.643 0.357 0.000
M43.8 Other specified deforming dorsopathies
0.643 0.357 0.000
M43.6 Torticollis
0.643 0.357 0.000
M43.5 Other recurrent vertebral subluxation
0.643 0.357 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.643 0.357 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.643 0.357 0.000
M43.2 Other fusion of spine
0.643 0.357 0.000
M43.0 Spondylolysis
0.643 0.357 0.000
H80 Otosclerosis
0.643 0.357 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.643 0.357 0.000
H53 Visual disturbances
0.643 0.357 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.642 0.358 0.000
L75 Apocrine sweat disorders
0.640 0.359 0.000
L74 Eccrine sweat disorders
0.640 0.359 0.000
L70 Acne
0.640 0.359 0.000
L68 Hypertrichosis
0.640 0.359 0.000
L67 Hair colour and hair shaft abnormalities
0.640 0.359 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.640 0.359 0.000
L65 Other nonscarring hair loss
0.640 0.359 0.000
L64 Androgenic alopecia
0.640 0.359 0.000
L63 Alopecia areata
0.640 0.359 0.000
L62 Nail disorders in diseases classified elsewhere
0.640 0.359 0.000
M87 Osteonecrosis
0.639 0.361 0.000
N41 Inflammatory diseases of prostate
0.639 0.361 0.000
L60 Nail disorders
0.638 0.362 0.000
H25.0 Senile incipient cataract
0.638 0.362 0.000
L73 Other follicular disorders
0.638 0.362 0.000
T40.4 Other synthetic narcotics
0.638 0.362 0.000
M80-M85 Disorders of bone density and structure
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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