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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13105680
log Bayes Factor = 13.3557
Chromosome 4   position 108,280,221  (GRCh37) Explore rs13105680 on Ensembl!
Variant rs13105680 is part of Cluster X0083

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
G90-G99 Other disorders of the nervous system
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
I30-I52 Other forms of heart disease
0.990 0.010 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
Chapter II Neoplasms
0.984 0.016 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.980 0.020 0.000
C44 Other malignant neoplasms of skin
0.979 0.021 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.978 0.022 0.000
M13 Other arthritis
0.976 0.024 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.976 0.024 0.000
E10 Insulin-dependent diabetes mellitus
0.975 0.025 0.000
R30-R39 Symptoms and signs involving the urinary system
0.975 0.025 0.000
C44.3 Skin of other and unspecified parts of face
0.974 0.026 0.000
M13.9 Arthritis, unspecified
0.973 0.027 0.000
E65-E68 Obesity and other hyperalimentation
0.970 0.030 0.000
R32 Unspecified urinary incontinence
0.963 0.037 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.960 0.040 0.000
G95 Other diseases of spinal cord
0.958 0.042 0.000
M50-M54 Other dorsopathies
0.956 0.044 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.956 0.044 0.000
I60-I69 Cerebrovascular diseases
0.955 0.045 0.000
E11.3 With ophthalmic complications
0.954 0.046 0.000
M70-M79 Other soft tissue disorders
0.952 0.048 0.000
C71 Malignant neoplasm of brain
0.942 0.058 0.000
I44 Atrioventricular and left bundle-branch block
0.942 0.058 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.941 0.059 0.000
M54 Dorsalgia
0.940 0.060 0.000
E66 Obesity
0.939 0.061 0.000
C44.6 Skin of upper limb, including shoulder
0.938 0.062 0.000
I49 Other cardiac arrhythmias
0.936 0.064 0.000
G93 Other disorders of brain
0.935 0.065 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.933 0.067 0.000
R39 Other symptoms and signs involving the urinary system
0.932 0.068 0.000
E66.8 Other obesity
0.932 0.068 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.923 0.077 0.000
I69 Sequelae of cerebrovascular disease
0.920 0.080 0.000
E11.5 With peripheral circulatory complications
0.919 0.081 0.000
M54.5 Low back pain
0.918 0.082 0.000
Chapter I Certain infectious and parasitic diseases
0.918 0.082 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.917 0.083 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.916 0.084 0.000
I46 Cardiac arrest
0.916 0.084 0.000
E11.4 With neurological complications
0.914 0.086 0.000
L89 Decubitus ulcer
0.912 0.088 0.000
I51 Complications and ill-defined descriptions of heart disease
0.907 0.093 0.000
E70-E90 Metabolic disorders
0.901 0.099 0.000
E10.9 Without complications
0.899 0.101 0.000
Chapter XX External causes of morbidity and mortality
0.899 0.101 0.000
L20-L30 Dermatitis and eczema
0.895 0.105 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.894 0.106 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.892 0.108 0.000
I26 Pulmonary embolism
0.892 0.108 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.888 0.112 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.887 0.113 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.886 0.114 0.000
G95.2 Cord compression, unspecified
0.886 0.114 0.000
R35 Polyuria
0.884 0.116 0.000
M54.59 Low back pain (Site unspecified)
0.884 0.116 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.880 0.120 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.875 0.125 0.000
E14 Unspecified diabetes mellitus
0.873 0.127 0.000
C71.9 Brain, unspecified
0.872 0.128 0.000
I49.8 Other specified cardiac arrhythmias
0.871 0.129 0.000
E20-E35 Disorders of other endocrine glands
0.871 0.129 0.000
D00-D09 In situ neoplasms
0.870 0.130 0.000
G30-G32 Other degenerative diseases of the nervous system
0.869 0.131 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.866 0.134 0.000
L90 Atrophic disorders of skin
0.862 0.138 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.862 0.138 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.858 0.142 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.857 0.143 0.000
G20-G26 Extrapyramidal and movement disorders
0.853 0.147 0.000
C44.4 Skin of scalp and neck
0.851 0.149 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.850 0.150 0.000
C50-C50 Malignant neoplasm of breast
0.849 0.151 0.000
I44.1 Atrioventricular block, second degree
0.849 0.151 0.000
G95.9 Disease of spinal cord, unspecified
0.848 0.152 0.000
R47-R49 Symptoms and signs involving speech and voice
0.847 0.153 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.842 0.158 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.838 0.162 0.000
Chapter VIII Diseases of the ear and mastoid process
0.837 0.163 0.000
I67 Other cerebrovascular diseases
0.834 0.166 0.000
M60-M63 Disorders of muscles
0.832 0.168 0.000
E10.0 With coma
0.829 0.171 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.828 0.172 0.000
L29 Pruritus
0.826 0.174 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.824 0.176 0.000
M86-M90 Other osteopathies
0.824 0.176 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.823 0.177 0.000
W00-W19 Falls
0.823 0.177 0.000
G70-G73 Diseases of myoneural junction and muscle
0.822 0.178 0.000
C71.1 Frontal lobe
0.822 0.178 0.000
M72 Fibroblastic disorders
0.820 0.180 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.817 0.183 0.000
I46.0 Cardiac arrest with successful resuscitation
0.816 0.184 0.000
M79.8 Other specified soft tissue disorders
0.814 0.186 0.000
E10.4 With neurological complications
0.810 0.190 0.000
C71.2 Temporal lobe
0.810 0.190 0.000
O80-O84 Delivery
0.810 0.190 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.809 0.191 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.809 0.191 0.000
E11.6 With other specified complications
0.809 0.191 0.000
M13.94 Arthritis, unspecified (Hand)
0.806 0.194 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.805 0.195 0.000
I49.5 Sick sinus syndrome
0.805 0.195 0.000
M91-M94 Chondropathies
0.804 0.196 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.802 0.198 0.000
L60-L75 Disorders of skin appendages
0.799 0.201 0.000
E83 Disorders of mineral metabolism
0.797 0.203 0.000
S90-S99 Injuries to the ankle and foot
0.797 0.203 0.000
M79.0 Rheumatism, unspecified
0.797 0.203 0.000
E10.5 With peripheral circulatory complications
0.796 0.204 0.000
C44.1 Skin of eyelid, including canthus
0.795 0.205 0.000
I51.9 Heart disease, unspecified
0.793 0.207 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.791 0.209 0.000
I42 Cardiomyopathy
0.790 0.210 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.787 0.212 0.000
E13 Other specified diabetes mellitus
0.786 0.214 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.784 0.216 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.781 0.219 0.000
M79.7 Fibromyalgia
0.781 0.219 0.000
I51.7 Cardiomegaly
0.781 0.219 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.780 0.220 0.000
Q80-Q89 Other congenital malformations
0.779 0.221 0.000
I46.9 Cardiac arrest, unspecified
0.779 0.221 0.000
D06 Carcinoma in situ of cervix uteri
0.778 0.222 0.000
O16 Unspecified maternal hypertension
0.778 0.222 0.000
G93.5 Compression of brain
0.777 0.223 0.000
R39.1 Other difficulties with micturition
0.776 0.224 0.000
I37 Pulmonary valve disorders
0.776 0.224 0.000
E65 Localised adiposity
0.776 0.224 0.000
E87.6 Hypokalaemia
0.775 0.225 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.775 0.225 0.000
I44.0 Atrioventricular block, first degree
0.775 0.225 0.000
Chapter V Mental and behavioural disorders
0.773 0.227 0.000
S50-S59 Injuries to the elbow and forearm
0.773 0.227 0.000
M54.3 Sciatica
0.771 0.228 0.000
M54.50 Low back pain (Multiple sites in spine)
0.771 0.229 0.000
Q60-Q64 Congenital malformations of the urinary system
0.771 0.229 0.000
L83 Acanthosis nigricans
0.769 0.231 0.000
E11.0 With coma
0.765 0.235 0.000
E14.9 Without complications
0.764 0.236 0.000
L90.0 Lichen sclerosus et atrophicus
0.763 0.236 0.000
Q50-Q56 Congenital malformations of genital organs
0.763 0.237 0.000
E16 Other disorders of pancreatic internal secretion
0.763 0.237 0.000
B35-B49 Mycoses
0.761 0.239 0.000
I10-I15 Hypertensive diseases
0.761 0.239 0.000
G40-G47 Episodic and paroxysmal disorders
0.761 0.239 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.760 0.240 0.000
I69.3 Sequelae of cerebral infarction
0.759 0.241 0.000
M79.9 Soft tissue disorder, unspecified
0.759 0.241 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.757 0.243 0.000
L27 Dermatitis due to substances taken internally
0.757 0.243 0.000
O80 Single spontaneous delivery
0.756 0.244 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.756 0.244 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.756 0.244 0.000
L85 Other epidermal thickening
0.755 0.244 0.000
M13.98 Arthritis, unspecified (Other)
0.755 0.245 0.000
E87.5 Hyperkalaemia
0.755 0.245 0.000
H90-H95 Other disorders of ear
0.755 0.245 0.000
C50 Malignant neoplasm of breast
0.753 0.247 0.000
L91 Hypertrophic disorders of skin
0.753 0.247 0.000
G93.9 Disorder of brain, unspecified
0.752 0.248 0.000
M54.4 Lumbago with sciatica
0.752 0.248 0.000
E28 Ovarian dysfunction
0.751 0.249 0.000
B25-B34 Other viral diseases
0.748 0.252 0.000
I33 Acute and subacute endocarditis
0.747 0.252 0.000
E10.1 With ketoacidosis
0.747 0.253 0.000
Chapter VII Diseases of the eye and adnexa
0.746 0.254 0.000
Y52 Agents primarily affecting the cardiovascular system
0.745 0.255 0.000
G93.8 Other specified disorders of brain
0.744 0.256 0.000
S60-S69 Injuries to the wrist and hand
0.744 0.256 0.000
I44.3 Other and unspecified atrioventricular block
0.740 0.260 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.740 0.260 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.739 0.261 0.000
R20 Disturbances of skin sensation
0.738 0.262 0.000
G24 Dystonia
0.738 0.262 0.000
I49.9 Cardiac arrhythmia, unspecified
0.737 0.263 0.000
I67.8 Other specified cerebrovascular diseases
0.736 0.264 0.000
R25 Abnormal involuntary movements
0.736 0.264 0.000
L60 Nail disorders
0.735 0.265 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.735 0.265 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.734 0.266 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.732 0.268 0.000
G90 Disorders of autonomic nervous system
0.732 0.268 0.000
C71.3 Parietal lobe
0.732 0.268 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.732 0.268 0.000
R47 Speech disturbances, not elsewhere classified
0.731 0.269 0.000
I50 Heart failure
0.729 0.271 0.000
G00 Bacterial meningitis, not elsewhere classified
0.728 0.272 0.000
L29.9 Pruritus, unspecified
0.728 0.272 0.000
T93 Sequelae of injuries of lower limb
0.728 0.272 0.000
E83.5 Disorders of calcium metabolism
0.727 0.273 0.000
I44.7 Left bundle-branch block, unspecified
0.727 0.273 0.000
W06 Fall involving bed
0.727 0.273 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.727 0.273 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.725 0.275 0.000
O80.0 Spontaneous vertex delivery
0.725 0.275 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.724 0.276 0.000
I27 Other pulmonary heart diseases
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
I30 Acute pericarditis
0.722 0.278 0.000
G93.6 Cerebral oedema
0.721 0.279 0.000
L40-L45 Papulosquamous disorders
0.721 0.279 0.000
M54.1 Radiculopathy
0.721 0.279 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.720 0.280 0.000
M71 Other bursopathies
0.720 0.280 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.720 0.280 0.000
R20.2 Paraesthesia of skin
0.719 0.281 0.000
I49.0 Ventricular fibrillation and flutter
0.719 0.281 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.718 0.282 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.717 0.283 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.717 0.283 0.000
I77 Other disorders of arteries and arterioles
0.716 0.284 0.000
M62 Other disorders of muscle
0.715 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
G30 Alzheimer's disease
0.715 0.285 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.715 0.285 0.000
G92 Toxic encephalopathy
0.715 0.285 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.715 0.285 0.000
E11.8 With unspecified complications
0.714 0.286 0.000
E11.7 With multiple complications
0.714 0.286 0.000
E11.1 With ketoacidosis
0.714 0.286 0.000
G93.3 Postviral fatigue syndrome
0.714 0.286 0.000
L84 Corns and callosities
0.714 0.286 0.000
D06.9 Cervix, unspecified
0.712 0.288 0.000
M77 Other enthesopathies
0.711 0.289 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.710 0.289 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.710 0.290 0.000
G93.2 Benign intracranial hypertension
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.710 0.290 0.000
I48 Atrial fibrillation and flutter
0.710 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.710 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.710 0.290 0.000
I40 Acute myocarditis
0.710 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.710 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.710 0.290 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.709 0.291 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
G95.8 Other specified diseases of spinal cord
0.707 0.293 0.000
G62 Other polyneuropathies
0.707 0.293 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.706 0.294 0.000
E00-E07 Disorders of thyroid gland
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
L50-L54 Urticaria and erythema
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.705 0.295 0.000
R26 Abnormalities of gait and mobility
0.704 0.296 0.000
L29.2 Pruritus vulvae
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.702 0.298 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
M12 Other specific arthropathies
0.702 0.298 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
C44.8 Overlapping lesion of skin
0.702 0.298 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.701 0.298 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.701 0.299 0.000
I67.2 Cerebral atherosclerosis
0.700 0.300 0.000
M13.8 Other specified arthritis
0.699 0.300 0.000
M13.1 Monoarthritis, not elsewhere classified
0.699 0.300 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.699 0.300 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.699 0.300 0.000
L94 Other localised connective tissue disorders
0.699 0.300 0.000
L87 Transepidermal elimination disorders
0.699 0.300 0.000
L88 Pyoderma gangrenosum
0.699 0.300 0.000
L86 Keratoderma in diseases classified elsewhere
0.699 0.300 0.000
L80 Vitiligo
0.699 0.300 0.000
E10.8 With unspecified complications
0.699 0.301 0.000
E10.7 With multiple complications
0.699 0.301 0.000
E10.6 With other specified complications
0.699 0.301 0.000
E10.2 With renal complications
0.699 0.301 0.000
R36 Urethral discharge
0.699 0.301 0.000
I42.2 Other hypertrophic cardiomyopathy
0.699 0.301 0.000
M13.93 Arthritis, unspecified (Forearm)
0.698 0.302 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.698 0.302 0.000
I45 Other conduction disorders
0.697 0.303 0.000
G93.4 Encephalopathy, unspecified
0.697 0.303 0.000
I72 Other aneurysm
0.696 0.304 0.000
E80.4 Gilbert's syndrome
0.696 0.304 0.000
M79.2 Neuralgia and neuritis, unspecified
0.695 0.304 0.000
E67 Other hyperalimentation
0.695 0.305 0.000
E68 Sequelae of hyperalimentation
0.695 0.305 0.000
D04 Carcinoma in situ of skin
0.695 0.305 0.000
C69 Malignant neoplasm of eye and adnexa
0.695 0.305 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.695 0.305 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.695 0.305 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.693 0.306 0.000
E16.2 Hypoglycaemia, unspecified
0.692 0.308 0.000
L89.1 Stage II decubitus ulcer
0.691 0.309 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.691 0.309 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.690 0.310 0.000
R30 Pain associated with micturition
0.690 0.310 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.689 0.311 0.000
H30-H36 Disorders of choroid and retina
0.689 0.311 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.688 0.312 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.688 0.312 0.000
C70 Malignant neoplasm of meninges
0.688 0.312 0.000
G40 Epilepsy
0.688 0.312 0.000
M05 Seropositive rheumatoid arthritis
0.688 0.312 0.000
G95.1 Vascular myelopathies
0.687 0.313 0.000
G95.0 Syringomyelia and syringobulbia
0.687 0.313 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.687 0.313 0.000
S10-S19 Injuries to the neck
0.685 0.315 0.000
I44.6 Other and unspecified fascicular block
0.685 0.315 0.000
L93 Lupus erythematosus
0.685 0.315 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.684 0.316 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.684 0.316 0.000
T79-T79 Certain early complications of trauma
0.684 0.316 0.000
E29 Testicular dysfunction
0.683 0.317 0.000
M76 Enthesopathies of lower limb, excluding foot
0.683 0.317 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.683 0.317 0.000
H60-H62 Diseases of external ear
0.682 0.317 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.682 0.318 0.000
A30-A49 Other bacterial diseases
0.682 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.681 0.319 0.000
R34 Anuria and oliguria
0.681 0.319 0.000
W07 Fall involving chair
0.680 0.319 0.000
I44.2 Atrioventricular block, complete
0.680 0.320 0.000
M79.79 Fibromyalgia (Site unspecified)
0.680 0.320 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.680 0.320 0.000
L91.0 Keloid scar
0.678 0.322 0.000
M86 Osteomyelitis
0.678 0.322 0.000
C50.5 Lower-outer quadrant of breast
0.678 0.322 0.000
G63.2 Diabetic polyneuropathy
0.677 0.323 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.676 0.323 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.676 0.324 0.000
C71.8 Overlapping lesion of brain
0.676 0.324 0.000
C71.7 Brain stem
0.676 0.324 0.000
C71.6 Cerebellum
0.676 0.324 0.000
C71.5 Cerebral ventricle
0.676 0.324 0.000
C71.4 Occipital lobe
0.676 0.324 0.000
C71.0 Cerebrum, except lobes and ventricles
0.676 0.324 0.000
I44.5 Left posterior fascicular block
0.676 0.324 0.000
I44.4 Left anterior fascicular block
0.676 0.324 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.676 0.324 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.675 0.325 0.000
I28 Other diseases of pulmonary vessels
0.675 0.325 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.674 0.325 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.674 0.326 0.000
M50 Cervical disk disorders
0.674 0.326 0.000
M54.8 Other dorsalgia
0.674 0.326 0.000
M54.6 Pain in thoracic spine
0.674 0.326 0.000
M54.0 Panniculitis affecting regions of neck and back
0.674 0.326 0.000
E11.2 With renal complications
0.673 0.326 0.000
M13.0 Polyarthritis, unspecified
0.673 0.326 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.673 0.327 0.000
E66.1 Drug-induced obesity
0.673 0.327 0.000
E66.0 Obesity due to excess calories
0.673 0.327 0.000
M06 Other rheumatoid arthritis
0.673 0.327 0.000
I12 Hypertensive renal disease
0.672 0.327 0.000
G03 Meningitis due to other and unspecified causes
0.671 0.329 0.000
I49.2 Junctional premature depolarisation
0.671 0.329 0.000
G93.7 Reye's syndrome
0.671 0.329 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.669 0.331 0.000
T33-T35 Frostbite
0.669 0.331 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.669 0.331 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.669 0.331 0.000
T00-T07 Injuries involving multiple body regions
0.669 0.331 0.000
R39.2 Extrarenal uraemia
0.668 0.331 0.000
R39.0 Extravasation of urine
0.668 0.331 0.000
M94 Other disorders of cartilage
0.668 0.332 0.000
S50 Superficial injury of forearm
0.668 0.332 0.000
E73 Lactose intolerance
0.668 0.332 0.000
E83.1 Disorders of iron metabolism
0.667 0.333 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.667 0.333 0.000
E14.3 With ophthalmic complications
0.667 0.333 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.667 0.333 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.666 0.333 0.000
S80-S89 Injuries to the knee and lower leg
0.666 0.333 0.000
G91 Hydrocephalus
0.666 0.334 0.000
V40-V49 Car occupant injured in transport accident
0.666 0.334 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.666 0.334 0.000
E28.2 Polycystic ovarian syndrome
0.665 0.335 0.000
W11 Fall on and from ladder
0.664 0.335 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.664 0.336 0.000
I49.1 Atrial premature depolarisation
0.663 0.337 0.000
M54.57 Low back pain (Lumbosacral region)
0.663 0.337 0.000
I62 Other nontraumatic intracranial haemorrhage
0.662 0.338 0.000
L90.5 Scar conditions and fibrosis of skin
0.662 0.338 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.662 0.338 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.661 0.338 0.000
M79.3 Panniculitis, unspecified
0.661 0.338 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.661 0.339 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.661 0.339 0.000
R33 Retention of urine
0.661 0.339 0.000
Q61 Cystic kidney disease
0.660 0.340 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.660 0.340 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.660 0.340 0.000
M79.1 Myalgia
0.660 0.340 0.000
H91 Other hearing loss
0.660 0.340 0.000
W06.0 Home
0.659 0.341 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.659 0.341 0.000
B99-B99 Other infectious diseases
0.658 0.342 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.658 0.342 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.658 0.342 0.000
B65-B83 Helminthiases
0.658 0.342 0.000
B50-B64 Protozoal diseases
0.658 0.342 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.658 0.342 0.000
A75-A79 Rickettsioses
0.658 0.342 0.000
A70-A74 Other diseases caused by chlamydiae
0.658 0.342 0.000
A65-A69 Other spirochaetal diseases
0.658 0.342 0.000
A20-A28 Certain zoonotic bacterial diseases
0.658 0.342 0.000
A15-A19 Tuberculosis
0.658 0.342 0.000
M54.55 Low back pain (Thoracolumbar region)
0.658 0.342 0.000
M54.54 Low back pain-Thoracic
0.658 0.342 0.000
M54.53 Low back pain-Cervicothoracic
0.658 0.342 0.000
M54.52 Low back pain-Cervical
0.658 0.342 0.000
M54.51 Low back pain-Occipit-atl-axl
0.658 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.658 0.342 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.658 0.342 0.000
Q35-Q37 Cleft lip and cleft palate
0.658 0.342 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.658 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.658 0.342 0.000
I46.1 Sudden cardiac death, so described
0.657 0.343 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.657 0.343 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.657 0.343 0.000
C44.7 Skin of lower limb, including hip
0.656 0.344 0.000
B37 Candidiasis
0.656 0.344 0.000
G60 Hereditary and idiopathic neuropathy
0.656 0.344 0.000
G12 Spinal muscular atrophy and related syndromes
0.655 0.345 0.000
G24.9 Dystonia, unspecified
0.655 0.345 0.000
G93.0 Cerebral cysts
0.655 0.345 0.000
L89.3 Stage IV decubitus ulcer
0.654 0.346 0.000
L89.2 Stage III decubitus ulcer
0.654 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
R47.8 Other and unspecified speech disturbances
0.652 0.348 0.000
C09 Malignant neoplasm of tonsil
0.652 0.348 0.000
R49 Voice disturbances
0.652 0.348 0.000
M90 Osteopathies in diseases classified elsewhere
0.651 0.348 0.000
W50-W64 Exposure to animate mechanical forces
0.651 0.349 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.651 0.349 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.651 0.349 0.000
L60.8 Other nail disorders
0.651 0.349 0.000
I51.6 Cardiovascular disease, unspecified
0.650 0.349 0.000
I51.5 Myocardial degeneration
0.650 0.349 0.000
I51.4 Myocarditis, unspecified
0.650 0.349 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.650 0.349 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.650 0.349 0.000
I51.0 Cardiac septal defect, acquired
0.650 0.349 0.000
M54.2 Cervicalgia
0.650 0.350 0.000
E11.9 Without complications
0.649 0.351 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.648 0.351 0.000
C50.3 Lower-inner quadrant of breast
0.648 0.352 0.000
M79.88 Other specified soft tissue disorders (Other)
0.647 0.353 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.647 0.353 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.647 0.353 0.000
C01 Malignant neoplasm of base of tongue
0.647 0.353 0.000
I60 Subarachnoid haemorrhage
0.647 0.353 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.646 0.354 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.646 0.354 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.646 0.354 0.000
C51-C58 Malignant neoplasms of female genital organs
0.646 0.354 0.000
E85 Amyloidosis
0.646 0.354 0.000
E84 Cystic fibrosis
0.646 0.354 0.000
E79 Disorders of purine and pyrimidine metabolism
0.646 0.354 0.000
E77 Disorders of glycoprotein metabolism
0.646 0.354 0.000
E76 Disorders of glycosaminoglycan metabolism
0.646 0.354 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.646 0.354 0.000
E74 Other disorders of carbohydrate metabolism
0.646 0.354 0.000
E72 Other disorders of amino-acid metabolism
0.646 0.354 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.646 0.354 0.000
E70 Disorders of aromatic amino-acid metabolism
0.646 0.354 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.646 0.354 0.000
V10-V19 Pedal cyclist injured in transport accident
0.645 0.355 0.000
I73 Other peripheral vascular diseases
0.645 0.355 0.000
I50.9 Heart failure, unspecified
0.645 0.355 0.000
E27 Other disorders of adrenal gland
0.645 0.355 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.645 0.355 0.000
Y35-Y36 Legal intervention and operations of war
0.644 0.356 0.000
Y10-Y34 Event of undetermined intent
0.644 0.356 0.000
Y00-Y09 Assault
0.644 0.356 0.000
X85-X99 Assault
0.644 0.356 0.000
X50-X57 Overexertion, travel and privation
0.644 0.356 0.000
X30-X39 Exposure to forces of nature
0.644 0.356 0.000
X20-X29 Contact with venomous animals and plants
0.644 0.356 0.000
X10-X19 Contact with heat and hot substances
0.644 0.356 0.000
X00-X09 Exposure to smoke, fire and flames
0.644 0.356 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.644 0.356 0.000
W75-W84 Other accidental threats to breathing
0.644 0.356 0.000
W65-W74 Accidental drowning and submersion
0.644 0.356 0.000
V98-V99 Other and unspecified transport accidents
0.644 0.356 0.000
V95-V97 Air and space transport accidents
0.644 0.356 0.000
V90-V94 Water transport accidents
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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