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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13227807
log Bayes Factor = 14.7212
Chromosome 7   position 68,454,912  (GRCh37) Explore rs13227807 on Ensembl!
Variant rs13227807 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.997 0.003 0.000
N17-N19 Renal failure
0.997 0.003 0.000
N18 Chronic renal failure
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.988 0.012 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.983 0.017 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.983 0.017 0.000
E00-E07 Disorders of thyroid gland
0.981 0.019 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.979 0.021 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.977 0.023 0.000
I30-I52 Other forms of heart disease
0.976 0.024 0.000
Z92 Personal history of medical treatment
0.973 0.027 0.000
E03 Other hypothyroidism
0.973 0.027 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.968 0.032 0.000
E03.9 Hypothyroidism, unspecified
0.965 0.035 0.000
C34 Malignant neoplasm of bronchus and lung
0.965 0.035 0.000
I42 Cardiomyopathy
0.965 0.035 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.964 0.036 0.000
E87.2 Acidosis
0.964 0.036 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.956 0.044 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.956 0.044 0.000
I10-I15 Hypertensive diseases
0.952 0.048 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.952 0.048 0.000
S00-S09 Injuries to the head
0.949 0.051 0.000
I45 Other conduction disorders
0.949 0.051 0.000
N20-N23 Urolithiasis
0.948 0.052 0.000
E87.7 Fluid overload
0.947 0.053 0.000
N83.2 Other and unspecified ovarian cysts
0.947 0.053 0.000
Chapter XX External causes of morbidity and mortality
0.946 0.054 0.000
E83 Disorders of mineral metabolism
0.942 0.058 0.000
Q60-Q64 Congenital malformations of the urinary system
0.942 0.058 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.942 0.058 0.000
N18.3 Chronic kidney disease, stage 3
0.936 0.064 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.935 0.065 0.000
N40-N51 Diseases of male genital organs
0.933 0.067 0.000
I45.1 Other and unspecified right bundle-branch block
0.933 0.067 0.000
I12 Hypertensive renal disease
0.931 0.069 0.000
Chapter VI Diseases of the nervous system
0.930 0.070 0.000
E87.6 Hypokalaemia
0.928 0.072 0.000
M50-M54 Other dorsopathies
0.922 0.078 0.000
C34.9 Bronchus or lung, unspecified
0.922 0.078 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.920 0.080 0.000
N40 Hyperplasia of prostate
0.917 0.083 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.915 0.085 0.000
N18.0 End-stage renal disease
0.913 0.087 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.913 0.087 0.000
Q61 Cystic kidney disease
0.913 0.087 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.907 0.093 0.000
S60-S69 Injuries to the wrist and hand
0.906 0.094 0.000
I12.0 Hypertensive renal disease with renal failure
0.905 0.095 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.903 0.097 0.000
I42.9 Cardiomyopathy, unspecified
0.902 0.098 0.000
Z46 Fitting and adjustment of other devices
0.901 0.099 0.000
N80 Endometriosis
0.897 0.103 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.897 0.103 0.000
N20 Calculus of kidney and ureter
0.895 0.105 0.000
Z45 Adjustment and management of implanted device
0.894 0.106 0.000
Z51 Other medical care
0.893 0.107 0.000
F10.0 Acute intoxication
0.892 0.108 0.000
Z98 Other postsurgical states
0.890 0.110 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.886 0.114 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.885 0.115 0.000
Z49 Care involving dialysis
0.884 0.116 0.000
N18.5 Chronic kidney disease, stage 5
0.880 0.120 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.875 0.125 0.000
N18.9 Chronic renal failure, unspecified
0.874 0.126 0.000
M54 Dorsalgia
0.874 0.126 0.000
N20.1 Calculus of ureter
0.874 0.126 0.000
N19 Unspecified renal failure
0.871 0.129 0.000
C34.3 Lower lobe, bronchus or lung
0.865 0.135 0.000
E20-E35 Disorders of other endocrine glands
0.863 0.137 0.000
F30-F39 Mood [affective] disorders
0.858 0.142 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.856 0.144 0.000
Z94 Transplanted organ and tissue status
0.852 0.148 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.852 0.148 0.000
Z13 Special screening examination for other diseases and disorders
0.851 0.149 0.000
S40-S49 Injuries to the shoulder and upper arm
0.851 0.149 0.000
M54.5 Low back pain
0.848 0.152 0.000
N80.9 Endometriosis, unspecified
0.848 0.152 0.000
C85.1 B-cell lymphoma, unspecified
0.848 0.152 0.000
C91 Lymphoid leukaemia
0.838 0.161 0.000
S00 Superficial injury of head
0.838 0.162 0.000
S50-S59 Injuries to the elbow and forearm
0.838 0.162 0.000
G40-G47 Episodic and paroxysmal disorders
0.837 0.163 0.000
E83.4 Disorders of magnesium metabolism
0.837 0.163 0.000
Q61.2 Polycystic kidney, adult type
0.836 0.164 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.836 0.164 0.000
Z51.1 Chemotherapy session for neoplasm
0.836 0.164 0.000
M45-M49 Spondylopathies
0.835 0.165 0.000
Q61.3 Polycystic kidney, unspecified
0.835 0.165 0.000
E78.5 Hyperlipidaemia, unspecified
0.834 0.166 0.000
S62 Fracture at wrist and hand level
0.832 0.168 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.831 0.169 0.000
M40-M43 Deforming dorsopathies
0.830 0.170 0.000
I42.0 Dilated cardiomyopathy
0.829 0.171 0.000
M80-M85 Disorders of bone density and structure
0.825 0.175 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.825 0.175 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.824 0.176 0.000
N83.1 Corpus luteum cyst
0.821 0.179 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.821 0.179 0.000
Chapter VIII Diseases of the ear and mastoid process
0.821 0.179 0.000
I42.2 Other hypertrophic cardiomyopathy
0.820 0.180 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.820 0.180 0.000
M54.59 Low back pain (Site unspecified)
0.818 0.182 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
E83.5 Disorders of calcium metabolism
0.816 0.184 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.811 0.189 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.811 0.189 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.810 0.190 0.000
S70-S79 Injuries to the hip and thigh
0.810 0.190 0.000
Z43 Attention to artificial openings
0.809 0.191 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.807 0.193 0.000
N80.1 Endometriosis of ovary
0.806 0.194 0.000
Z46.6 Fitting and adjustment of urinary device
0.805 0.195 0.000
Z51.5 Palliative care
0.804 0.196 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.804 0.196 0.000
Chapter I Certain infectious and parasitic diseases
0.801 0.199 0.000
M51 Other intervertebral disk disorders
0.800 0.200 0.000
Z92.3 Personal history of irradiation
0.796 0.204 0.000
W00-W19 Falls
0.796 0.204 0.000
I60-I69 Cerebrovascular diseases
0.795 0.205 0.000
S01 Open wound of head
0.794 0.206 0.000
I05-I09 Chronic rheumatic heart diseases
0.793 0.207 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.791 0.209 0.000
E73 Lactose intolerance
0.790 0.210 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.789 0.211 0.000
Z87 Personal history of other diseases and conditions
0.788 0.212 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.788 0.212 0.000
C44 Other malignant neoplasms of skin
0.788 0.212 0.000
C34.1 Upper lobe, bronchus or lung
0.786 0.214 0.000
Z94.0 Kidney transplant status
0.786 0.214 0.000
Z13.9 Special screening examination, unspecified
0.782 0.218 0.000
N18.4 Chronic kidney disease, stage 4
0.781 0.219 0.000
F29 Unspecified nonorganic psychosis
0.781 0.219 0.000
I49 Other cardiac arrhythmias
0.780 0.220 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.780 0.220 0.000
N21 Calculus of lower urinary tract
0.779 0.221 0.000
S32 Fracture of lumbar spine and pelvis
0.779 0.221 0.000
N43 Hydrocele and spermatocele
0.779 0.221 0.000
G90-G99 Other disorders of the nervous system
0.778 0.222 0.000
T92 Sequelae of injuries of upper limb
0.776 0.224 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.776 0.224 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.775 0.225 0.000
S06 Intracranial injury
0.775 0.225 0.000
I12.9 Hypertensive renal disease without renal failure
0.774 0.226 0.000
E04 Other non-toxic goitre
0.773 0.227 0.000
I31 Other diseases of pericardium
0.773 0.227 0.000
E03.8 Other specified hypothyroidism
0.773 0.227 0.000
V10-V19 Pedal cyclist injured in transport accident
0.772 0.228 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.771 0.228 0.000
C79 Secondary malignant neoplasm of other sites
0.767 0.233 0.000
N10-N16 Renal tubulo-interstitial diseases
0.765 0.235 0.000
Z98.8 Other specified postsurgical states
0.765 0.235 0.000
Z88.5 Personal history of allergy to narcotic agent
0.764 0.236 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.763 0.237 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.762 0.238 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.762 0.238 0.000
E88 Other metabolic disorders
0.762 0.238 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.761 0.239 0.000
V80-V89 Other land transport accidents
0.760 0.240 0.000
Z12 Special screening examination for neoplasms
0.757 0.243 0.000
Z92.0 Personal history of contraception
0.757 0.243 0.000
Q80-Q89 Other congenital malformations
0.755 0.245 0.000
F17.2 Dependence syndrome
0.755 0.245 0.000
F60-F69 Disorders of adult personality and behaviour
0.753 0.247 0.000
I15 Secondary hypertension
0.752 0.248 0.000
D00-D09 In situ neoplasms
0.752 0.248 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.751 0.249 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.750 0.250 0.000
S64 Injury of nerves at wrist and hand level
0.749 0.251 0.000
I27 Other pulmonary heart diseases
0.749 0.251 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
Z93 Artificial opening status
0.746 0.254 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.746 0.254 0.000
N00-N08 Glomerular diseases
0.744 0.256 0.000
Z98.0 Intestinal bypass and anastomosis status
0.744 0.256 0.000
M86-M90 Other osteopathies
0.742 0.258 0.000
M43 Other deforming dorsopathies
0.742 0.258 0.000
S09 Other and unspecified injuries of head
0.741 0.259 0.000
V20-V29 Motorcycle rider injured in transport accident
0.741 0.259 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.740 0.260 0.000
S10-S19 Injuries to the neck
0.740 0.260 0.000
M47 Spondylosis
0.740 0.260 0.000
C91.1 Chronic lymphocytic leukaemia
0.739 0.261 0.000
Z89 Acquired absence of limb
0.739 0.261 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.738 0.262 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.737 0.263 0.000
Z53.9 Procedure not carried out, unspecified reason
0.737 0.263 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.735 0.265 0.000
C44.2 Skin of ear and external auricular canal
0.734 0.266 0.000
Z45.2 Adjustment and management of vascular access device
0.732 0.268 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.732 0.268 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.732 0.268 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.731 0.269 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.729 0.271 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.729 0.271 0.000
Z49.0 Preparatory care for dialysis
0.728 0.272 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.727 0.273 0.000
M60-M63 Disorders of muscles
0.726 0.274 0.000
S42 Fracture of shoulder and upper arm
0.726 0.274 0.000
E83.3 Disorders of phosphorus metabolism
0.726 0.274 0.000
G30-G32 Other degenerative diseases of the nervous system
0.725 0.275 0.000
S20-S29 Injuries to the thorax
0.725 0.275 0.000
C92 Myeloid leukaemia
0.725 0.275 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.724 0.276 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.721 0.279 0.000
Z42 Follow-up care involving plastic surgery
0.721 0.279 0.000
S00.0 Superficial injury of scalp
0.721 0.279 0.000
N87 Dysplasia of cervix uteri
0.721 0.279 0.000
Z49.2 Other dialysis
0.718 0.282 0.000
F20 Schizophrenia
0.718 0.282 0.000
N99-N99 Other disorders of the genitourinary system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
M51.2 Other specified intervertebral disk displacement
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
N41 Inflammatory diseases of prostate
0.715 0.285 0.000
Y95 Nosocomial condition
0.715 0.285 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.715 0.285 0.000
E87.4 Mixed disorder of acid-base balance
0.715 0.285 0.000
E87.3 Alkalosis
0.715 0.285 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.715 0.285 0.000
E87.0 Hyperosmolality and hypernatraemia
0.714 0.286 0.000
M91-M94 Chondropathies
0.713 0.286 0.000
N50 Other disorders of male genital organs
0.713 0.287 0.000
G70-G73 Diseases of myoneural junction and muscle
0.713 0.287 0.000
N18.8 Other chronic renal failure
0.712 0.288 0.000
N18.2 Chronic kidney disease, stage 2
0.712 0.288 0.000
N18.1 Chronic kidney disease, stage 1
0.712 0.288 0.000
C64-C68 Malignant neoplasms of urinary tract
0.712 0.288 0.000
E06 Thyroiditis
0.711 0.289 0.000
C71 Malignant neoplasm of brain
0.711 0.289 0.000
N60-N64 Disorders of breast
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
E50-E64 Other nutritional deficiencies
0.709 0.290 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.709 0.291 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.708 0.292 0.000
Z54 Convalescence
0.708 0.292 0.000
Z44 Fitting and adjustment of external prosthetic device
0.708 0.292 0.000
S80-S89 Injuries to the knee and lower leg
0.707 0.293 0.000
Z48 Other surgical follow-up care
0.706 0.294 0.000
S62.3 Fracture of other metacarpal bone
0.705 0.295 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.705 0.295 0.000
Q50-Q56 Congenital malformations of genital organs
0.705 0.295 0.000
Q35-Q37 Cleft lip and cleft palate
0.705 0.295 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.705 0.295 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.705 0.295 0.000
Q00-Q07 Congenital malformations of the nervous system
0.705 0.295 0.000
C34.0 Main bronchus
0.705 0.295 0.000
Z49.1 Extracorporeal dialysis
0.705 0.295 0.000
Z84 Family history of other conditions
0.705 0.295 0.000
Z81 Family history of mental and behavioural disorders
0.705 0.295 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.703 0.297 0.000
E00 Congenital iodine-deficiency syndrome
0.703 0.297 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.703 0.297 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.702 0.298 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.702 0.298 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.702 0.298 0.000
C32 Malignant neoplasm of larynx
0.702 0.298 0.000
C31 Malignant neoplasm of accessory sinuses
0.702 0.298 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.702 0.298 0.000
C37 Malignant neoplasm of thymus
0.702 0.298 0.000
C33 Malignant neoplasm of trachea
0.702 0.298 0.000
F31 Bipolar affective disorder
0.702 0.298 0.000
Z52 Donors of organs and tissues
0.701 0.298 0.000
S52 Fracture of forearm
0.702 0.298 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.701 0.299 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.700 0.300 0.000
C95 Leukaemia of unspecified cell type
0.700 0.300 0.000
C94 Other leukaemias of specified cell type
0.700 0.300 0.000
C93 Monocytic leukaemia
0.700 0.300 0.000
C88 Malignant immunoproliferative diseases
0.700 0.300 0.000
C86 Other specified types of T/NK-cell lymphoma
0.700 0.300 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.700 0.300 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
I52 Other heart disorders in diseases classified elsewhere
0.700 0.300 0.000
I48 Atrial fibrillation and flutter
0.700 0.300 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.700 0.300 0.000
I41 Myocarditis in diseases classified elsewhere
0.700 0.300 0.000
I40 Acute myocarditis
0.700 0.300 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.700 0.300 0.000
I37 Pulmonary valve disorders
0.700 0.300 0.000
I36 Nonrheumatic tricuspid valve disorders
0.700 0.300 0.000
I32 Pericarditis in diseases classified elsewhere
0.700 0.300 0.000
I30 Acute pericarditis
0.700 0.300 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.700 0.300 0.000
Z92.9 Personal history of medical treatment, unspecified
0.698 0.302 0.000
Z92.8 Personal history of other medical treatment
0.698 0.302 0.000
Z92.5 Personal history of rehabilitation measures
0.698 0.302 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.698 0.302 0.000
E03.5 Myxoedema coma
0.698 0.302 0.000
E03.4 Atrophy of thyroid (acquired)
0.698 0.302 0.000
E03.3 Postinfectious hypothyroidism
0.698 0.302 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.698 0.302 0.000
E03.1 Congenital hypothyroidism without goitre
0.698 0.302 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.698 0.302 0.000
Z45.8 Adjustment and management of other implanted devices
0.695 0.305 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.695 0.305 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.695 0.305 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.694 0.306 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.307 0.000
G40 Epilepsy
0.692 0.308 0.000
C81 Hodgkin's disease
0.692 0.308 0.000
C34.8 Overlapping lesion of bronchus and lung
0.692 0.308 0.000
C34.2 Middle lobe, bronchus or lung
0.692 0.308 0.000
E86 Volume depletion
0.692 0.308 0.000
I50 Heart failure
0.692 0.308 0.000
I42.8 Other cardiomyopathies
0.692 0.308 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.692 0.308 0.000
I42.6 Alcoholic cardiomyopathy
0.692 0.308 0.000
I42.5 Other restrictive cardiomyopathy
0.692 0.308 0.000
I42.4 Endocardial fibroelastosis
0.692 0.308 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.692 0.308 0.000
M80 Osteoporosis with pathological fracture
0.691 0.308 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.691 0.309 0.000
Z87.0 Personal history of diseases of the respiratory system
0.691 0.309 0.000
G20-G26 Extrapyramidal and movement disorders
0.690 0.310 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.689 0.311 0.000
I33 Acute and subacute endocarditis
0.687 0.313 0.000
H60-H62 Diseases of external ear
0.687 0.313 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.686 0.313 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.686 0.314 0.000
F10.1 Harmful use
0.686 0.314 0.000
M00-M03 Infectious arthropathies
0.685 0.315 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.685 0.315 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.685 0.315 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.685 0.315 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.685 0.315 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.685 0.315 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.685 0.315 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.685 0.315 0.000
F11 Mental and behavioural disorders due to use of opioids
0.685 0.315 0.000
A30-A49 Other bacterial diseases
0.685 0.315 0.000
I49.9 Cardiac arrhythmia, unspecified
0.684 0.316 0.000
S01.0 Open wound of scalp
0.684 0.316 0.000
Z83 Family history of other specific disorders
0.683 0.317 0.000
I13 Hypertensive heart and renal disease
0.683 0.317 0.000
I11 Hypertensive heart disease
0.683 0.317 0.000
T92.0 Sequelae of open wound of upper limb
0.682 0.318 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.682 0.318 0.000
S40 Superficial injury of shoulder and upper arm
0.682 0.318 0.000
I05 Rheumatic mitral valve diseases
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.681 0.319 0.000
S07 Crushing injury of head
0.681 0.319 0.000
S05 Injury of eye and orbit
0.681 0.319 0.000
S04 Injury of cranial nerves
0.681 0.319 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.681 0.319 0.000
I45.9 Conduction disorder, unspecified
0.681 0.319 0.000
I45.8 Other specified conduction disorders
0.681 0.319 0.000
I45.5 Other specified heart block
0.681 0.319 0.000
I45.4 Nonspecific intraventricular block
0.681 0.319 0.000
I45.3 Trifascicular block
0.681 0.319 0.000
I45.2 Bifascicular block
0.681 0.319 0.000
I45.0 Right fascicular block
0.681 0.319 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.319 0.000
N83.0 Follicular cyst of ovary
0.680 0.320 0.000
M84 Disorders of continuity of bone
0.680 0.320 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.680 0.320 0.000
Z01.9 Special examination, unspecified
0.679 0.321 0.000
F30 Manic episode
0.679 0.321 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.678 0.321 0.000
M43.1 Spondylolisthesis
0.678 0.322 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.678 0.322 0.000
Y35-Y36 Legal intervention and operations of war
0.678 0.322 0.000
Y10-Y34 Event of undetermined intent
0.678 0.322 0.000
Y00-Y09 Assault
0.678 0.322 0.000
X85-X99 Assault
0.678 0.322 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.678 0.322 0.000
X50-X57 Overexertion, travel and privation
0.678 0.322 0.000
X30-X39 Exposure to forces of nature
0.678 0.322 0.000
X20-X29 Contact with venomous animals and plants
0.678 0.322 0.000
X10-X19 Contact with heat and hot substances
0.678 0.322 0.000
X00-X09 Exposure to smoke, fire and flames
0.678 0.322 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.678 0.322 0.000
W75-W84 Other accidental threats to breathing
0.678 0.322 0.000
W65-W74 Accidental drowning and submersion
0.678 0.322 0.000
W50-W64 Exposure to animate mechanical forces
0.678 0.322 0.000
V98-V99 Other and unspecified transport accidents
0.678 0.322 0.000
V95-V97 Air and space transport accidents
0.678 0.322 0.000
V90-V94 Water transport accidents
0.678 0.322 0.000
V70-V79 Bus occupant injured in transport accident
0.678 0.322 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.678 0.322 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.678 0.322 0.000
V40-V49 Car occupant injured in transport accident
0.678 0.322 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.678 0.322 0.000
V01-V09 Pedestrian injured in transport accident
0.678 0.322 0.000
T93 Sequelae of injuries of lower limb
0.678 0.322 0.000
Q61.0 Congenital single renal cyst
0.678 0.322 0.000
E23 Hypofunction and other disorders of pituitary gland
0.677 0.323 0.000
T79-T79 Certain early complications of trauma
0.677 0.323 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.676 0.324 0.000
E83.8 Other disorders of mineral metabolism
0.676 0.324 0.000
E83.2 Disorders of zinc metabolism
0.676 0.324 0.000
E83.0 Disorders of copper metabolism
0.676 0.324 0.000
Q64 Other congenital malformations of urinary system
0.676 0.324 0.000
Q63 Other congenital malformations of kidney
0.676 0.324 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.676 0.324 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.676 0.324 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.675 0.325 0.000
N83.7 Haematoma of broad ligament
0.675 0.325 0.000
N83.6 Haematosalpinx
0.675 0.325 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.675 0.325 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.675 0.325 0.000
N80.2 Endometriosis of Fallopian tube
0.674 0.326 0.000
E83.1 Disorders of iron metabolism
0.673 0.326 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.673 0.327 0.000
I69 Sequelae of cerebrovascular disease
0.673 0.327 0.000
Y85 Sequelae of transport accidents
0.672 0.328 0.000
C77.3 Axillary and upper limb lymph nodes
0.672 0.328 0.000
G90 Disorders of autonomic nervous system
0.671 0.329 0.000
N25-N29 Other disorders of kidney and ureter
0.670 0.330 0.000
N98 Complications associated with artificial fertilisation
0.670 0.330 0.000
N91 Absent, scanty and rare menstruation
0.670 0.330 0.000
N82 Fistulae involving female genital tract
0.670 0.330 0.000
N96 Habitual aborter
0.670 0.330 0.000
M54.3 Sciatica
0.670 0.330 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.669 0.331 0.000
N46 Male infertility
0.669 0.331 0.000
N44 Torsion of testis
0.669 0.331 0.000
E78.0 Pure hypercholesterolaemia
0.669 0.331 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.669 0.331 0.000
I44 Atrioventricular and left bundle-branch block
0.669 0.331 0.000
F32 Depressive episode
0.668 0.332 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.668 0.332 0.000
N43.3 Hydrocele, unspecified
0.668 0.332 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.667 0.333 0.000
N90.5 Atrophy of vulva
0.666 0.334 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.666 0.334 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.665 0.335 0.000
S00.8 Superficial injury of other parts of head
0.665 0.335 0.000
M48 Other spondylopathies
0.665 0.335 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
S60 Superficial injury of wrist and hand
0.663 0.337 0.000
I27.9 Pulmonary heart disease, unspecified
0.662 0.338 0.000
C50-C50 Malignant neoplasm of breast
0.662 0.338 0.000
Z98.1 Arthrodesis status
0.661 0.339 0.000
S02 Fracture of skull and facial bones
0.660 0.340 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.660 0.340 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.660 0.340 0.000
C85.0 Lymphosarcoma
0.660 0.340 0.000
N21.0 Calculus in bladder
0.658 0.342 0.000
T90 Sequelae of injuries of head
0.658 0.342 0.000
I38 Endocarditis, valve unspecified
0.657 0.342 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.656 0.344 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.656 0.344 0.000
S62.6 Fracture of other finger
0.656 0.344 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.656 0.344 0.000
F10.9 Unspecified mental and behavioural disorder
0.655 0.345 0.000
F10.8 Other mental and behavioural disorders
0.655 0.345 0.000
F10.7 Residual and late-onset psychotic disorder
0.655 0.345 0.000
F10.6 Amnesic syndrome
0.655 0.345 0.000
F10.5 Psychotic disorder
0.655 0.345 0.000
F10.4 Withdrawal state with delirium
0.655 0.345 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.655 0.345 0.000
I31.3 Pericardial effusion (noninflammatory)
0.655 0.345 0.000
Q61.9 Cystic kidney disease, unspecified
0.655 0.345 0.000
Q61.8 Other cystic kidney diseases
0.655 0.345 0.000
Q61.5 Medullary cystic kidney
0.655 0.345 0.000
Q61.4 Renal dysplasia
0.655 0.345 0.000
Q61.1 Polycystic kidney, infantile type
0.655 0.345 0.000
E87.5 Hyperkalaemia
0.652 0.347 0.000
Y88 Sequelae of surgical and medical care as external cause
0.651 0.349 0.000
S72 Fracture of femur
0.650 0.350 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.650 0.350 0.000
Z10 Routine general health check-up of defined subpopulation
0.650 0.350 0.000
S69 Other and unspecified injuries of wrist and hand
0.649 0.351 0.000
S65 Injury of blood vessels at wrist and hand level
0.649 0.351 0.000
I61 Intracerebral haemorrhage
0.649 0.351 0.000
S42.2 Fracture of upper end of humerus
0.649 0.351 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.648 0.352 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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