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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138292237
log Bayes Factor = 14.389
Chromosome 19   position 21,910,125  (GRCh37) Explore rs138292237 on Ensembl!
Variant rs138292237 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.987 0.013 0.000
M54 Dorsalgia
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.978 0.022 0.000
M70-M79 Other soft tissue disorders
0.971 0.029 0.000
M05-M14 Inflammatory polyarthropathies
0.969 0.031 0.000
I51 Complications and ill-defined descriptions of heart disease
0.968 0.032 0.000
M51 Other intervertebral disk disorders
0.967 0.033 0.000
N17-N19 Renal failure
0.963 0.037 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.960 0.040 0.000
I10-I15 Hypertensive diseases
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.957 0.043 0.000
Chapter XX External causes of morbidity and mortality
0.955 0.045 0.000
M20-M25 Other joint disorders
0.952 0.048 0.000
N18 Chronic renal failure
0.947 0.053 0.000
M51.2 Other specified intervertebral disk displacement
0.941 0.059 0.000
H30-H36 Disorders of choroid and retina
0.940 0.060 0.000
M25 Other joint disorders, not elsewhere classified
0.938 0.062 0.000
M75 Shoulder lesions
0.936 0.064 0.000
M45-M49 Spondylopathies
0.932 0.068 0.000
N20-N23 Urolithiasis
0.929 0.071 0.000
M54.3 Sciatica
0.926 0.074 0.000
S00-S09 Injuries to the head
0.926 0.074 0.000
M25.5 Pain in joint
0.922 0.078 0.000
I49 Other cardiac arrhythmias
0.916 0.084 0.000
I20-I25 Ischaemic heart diseases
0.916 0.084 0.000
E10-E14 Diabetes mellitus
0.912 0.088 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.911 0.089 0.000
M13 Other arthritis
0.909 0.091 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.904 0.096 0.000
J09-J18 Influenza and pneumonia
0.899 0.101 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.899 0.101 0.000
I51.7 Cardiomegaly
0.898 0.102 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.896 0.104 0.000
N60-N64 Disorders of breast
0.896 0.104 0.000
S80-S89 Injuries to the knee and lower leg
0.894 0.106 0.000
J95-J99 Other diseases of the respiratory system
0.893 0.107 0.000
M75.4 Impingement syndrome of shoulder
0.889 0.111 0.000
H35 Other retinal disorders
0.885 0.115 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.879 0.121 0.000
J90-J94 Other diseases of pleura
0.879 0.121 0.000
J60-J70 Lung diseases due to external agents
0.879 0.121 0.000
I60-I69 Cerebrovascular diseases
0.878 0.122 0.000
I10 Essential (primary) hypertension
0.876 0.124 0.000
I51.8 Other ill-defined heart diseases
0.871 0.129 0.000
I05-I09 Chronic rheumatic heart diseases
0.869 0.131 0.000
I12 Hypertensive renal disease
0.868 0.132 0.000
M13.9 Arthritis, unspecified
0.867 0.133 0.000
N18.3 Chronic kidney disease, stage 3
0.866 0.134 0.000
N18.5 Chronic kidney disease, stage 5
0.863 0.137 0.000
S20-S29 Injuries to the thorax
0.861 0.139 0.000
J00-J06 Acute upper respiratory infections
0.861 0.139 0.000
S00 Superficial injury of head
0.858 0.142 0.000
Chapter XXI Factors influencing health status and contact with health services
0.857 0.143 0.000
M10 Gout
0.856 0.144 0.000
N20 Calculus of kidney and ureter
0.854 0.146 0.000
E11 Non-insulin-dependent diabetes mellitus
0.852 0.148 0.000
M54.39 Sciatica (Site unspecified)
0.849 0.151 0.000
J84 Other interstitial pulmonary diseases
0.847 0.153 0.000
M54.5 Low back pain
0.846 0.154 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.845 0.155 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.845 0.155 0.000
G57 Mononeuropathies of lower limb
0.841 0.159 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.841 0.159 0.000
H36 Retinal disorders in diseases classified elsewhere
0.834 0.166 0.000
G90-G99 Other disorders of the nervous system
0.833 0.167 0.000
M47 Spondylosis
0.829 0.171 0.000
T81 Complications of procedures, not elsewhere classified
0.828 0.172 0.000
I63 Cerebral infarction
0.827 0.173 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.824 0.176 0.000
H53-H54 Visual disturbances and blindness
0.817 0.183 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.817 0.183 0.000
J92 Pleural plaque
0.817 0.183 0.000
M22 Disorders of patella
0.816 0.184 0.000
I95 Hypotension
0.815 0.185 0.000
I35 Nonrheumatic aortic valve disorders
0.814 0.186 0.000
J18 Pneumonia, organism unspecified
0.813 0.187 0.000
H40-H42 Glaucoma
0.811 0.189 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.810 0.190 0.000
N18.0 End-stage renal disease
0.809 0.191 0.000
M25.51 Pain in joint (Shoulder region)
0.805 0.195 0.000
E70-E90 Metabolic disorders
0.802 0.198 0.000
G57.6 Lesion of plantar nerve
0.802 0.198 0.000
I12.0 Hypertensive renal disease with renal failure
0.802 0.198 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.800 0.200 0.000
M54.59 Low back pain (Site unspecified)
0.798 0.202 0.000
N99-N99 Other disorders of the genitourinary system
0.798 0.202 0.000
I47 Paroxysmal tachycardia
0.797 0.203 0.000
M54.36 Sciatica (Lumbar region)
0.796 0.204 0.000
M54.9 Dorsalgia, unspecified
0.795 0.205 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.794 0.206 0.000
N21 Calculus of lower urinary tract
0.792 0.208 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.792 0.208 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.790 0.210 0.000
M65-M68 Disorders of synovium and tendon
0.790 0.210 0.000
I51.9 Heart disease, unspecified
0.790 0.210 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.790 0.210 0.000
W00-W19 Falls
0.789 0.210 0.000
E10 Insulin-dependent diabetes mellitus
0.789 0.211 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.788 0.212 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.788 0.212 0.000
H35.8 Other specified retinal disorders
0.788 0.212 0.000
M25.57 Pain in joint (Ankle and foot)
0.787 0.213 0.000
E11.3 With ophthalmic complications
0.786 0.214 0.000
M47.9 Spondylosis, unspecified
0.784 0.216 0.000
N00-N08 Glomerular diseases
0.783 0.217 0.000
I20 Angina pectoris
0.783 0.217 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.781 0.219 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.781 0.219 0.000
N62 Hypertrophy of breast
0.779 0.221 0.000
H55-H59 Other disorders of eye and adnexa
0.779 0.221 0.000
S00.0 Superficial injury of scalp
0.779 0.221 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.778 0.222 0.000
H35.3 Degeneration of macula and posterior pole
0.778 0.222 0.000
S01 Open wound of head
0.777 0.223 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.777 0.223 0.000
M10.9 Gout, unspecified
0.776 0.224 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.775 0.225 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.774 0.226 0.000
S90-S99 Injuries to the ankle and foot
0.774 0.226 0.000
S40-S49 Injuries to the shoulder and upper arm
0.774 0.226 0.000
J98 Other respiratory disorders
0.773 0.227 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.772 0.227 0.000
I49.8 Other specified cardiac arrhythmias
0.772 0.228 0.000
M48 Other spondylopathies
0.772 0.228 0.000
M75.0 Adhesive capsulitis of shoulder
0.771 0.229 0.000
S82 Fracture of lower leg, including ankle
0.770 0.230 0.000
N60 Benign mammary dysplasia
0.770 0.230 0.000
M25.53 Pain in joint (Forearm)
0.770 0.230 0.000
N20.0 Calculus of kidney
0.764 0.236 0.000
I24 Other acute ischaemic heart diseases
0.763 0.237 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.761 0.239 0.000
I30 Acute pericarditis
0.761 0.239 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
I25 Chronic ischaemic heart disease
0.759 0.241 0.000
J20-J22 Other acute lower respiratory infections
0.759 0.241 0.000
H36.0 Diabetic retinopathy
0.758 0.242 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.757 0.243 0.000
W20-W49 Exposure to inanimate mechanical forces
0.756 0.244 0.000
I49.0 Ventricular fibrillation and flutter
0.756 0.244 0.000
I33 Acute and subacute endocarditis
0.755 0.245 0.000
M40-M43 Deforming dorsopathies
0.755 0.245 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.754 0.246 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.753 0.247 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.753 0.247 0.000
I49.3 Ventricular premature depolarisation
0.752 0.248 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.752 0.248 0.000
E50-E64 Other nutritional deficiencies
0.751 0.249 0.000
M75.2 Bicipital tendinitis
0.749 0.251 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.748 0.252 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.745 0.255 0.000
S70-S79 Injuries to the hip and thigh
0.744 0.256 0.000
J92.0 Pleural plaque with presence of asbestos
0.744 0.256 0.000
M25.8 Other specified joint disorders
0.743 0.257 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.742 0.258 0.000
S60-S69 Injuries to the wrist and hand
0.741 0.259 0.000
M54.4 Lumbago with sciatica
0.740 0.260 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.739 0.261 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.739 0.261 0.000
N25-N29 Other disorders of kidney and ureter
0.738 0.262 0.000
I44 Atrioventricular and left bundle-branch block
0.737 0.262 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.737 0.263 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.737 0.263 0.000
H10-H13 Disorders of conjunctiva
0.736 0.263 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.736 0.264 0.000
N18.9 Chronic renal failure, unspecified
0.736 0.264 0.000
Z99.2 Dependence on renal dialysis
0.735 0.265 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.734 0.266 0.000
I95.9 Hypotension, unspecified
0.732 0.268 0.000
I63.9 Cerebral infarction, unspecified
0.731 0.269 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.731 0.269 0.000
E78.0 Pure hypercholesterolaemia
0.730 0.270 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.729 0.271 0.000
I31 Other diseases of pericardium
0.728 0.272 0.000
I69 Sequelae of cerebrovascular disease
0.728 0.272 0.000
I08 Multiple valve diseases
0.728 0.272 0.000
M54.1 Radiculopathy
0.728 0.272 0.000
Q21 Congenital malformations of cardiac septa
0.727 0.273 0.000
E11.2 With renal complications
0.726 0.274 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.725 0.275 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.723 0.277 0.000
M80-M85 Disorders of bone density and structure
0.722 0.277 0.000
M45 Ankylosing spondylitis
0.722 0.278 0.000
J02 Acute pharyngitis
0.720 0.280 0.000
I20.9 Angina pectoris, unspecified
0.720 0.280 0.000
M86-M90 Other osteopathies
0.719 0.281 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.718 0.282 0.000
M10.99 Gout, unspecified (Site unspecified)
0.718 0.282 0.000
M24 Other specific joint derangements
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M25.7 Osteophyte
0.715 0.284 0.000
M06 Other rheumatoid arthritis
0.715 0.285 0.000
M54.2 Cervicalgia
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
M25.56 Pain in joint (Lower leg)
0.713 0.286 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
S29 Other and unspecified injuries of thorax
0.713 0.287 0.000
S50-S59 Injuries to the elbow and forearm
0.713 0.287 0.000
H54 Blindness and low vision
0.713 0.287 0.000
E11.1 With ketoacidosis
0.712 0.288 0.000
T79-T79 Certain early complications of trauma
0.712 0.288 0.000
T66-T78 Other and unspecified effects of external causes
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
S10-S19 Injuries to the neck
0.712 0.288 0.000
H34 Retinal vascular occlusions
0.712 0.288 0.000
J69 Pneumonitis due to solids and liquids
0.711 0.289 0.000
Z60 Problems related to social environment
0.711 0.289 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.711 0.289 0.000
I52 Other heart disorders in diseases classified elsewhere
0.710 0.290 0.000
I48 Atrial fibrillation and flutter
0.710 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.710 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.710 0.290 0.000
I40 Acute myocarditis
0.710 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.710 0.290 0.000
I37 Pulmonary valve disorders
0.710 0.290 0.000
I36 Nonrheumatic tricuspid valve disorders
0.710 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.710 0.290 0.000
I63.8 Other cerebral infarction
0.710 0.290 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.710 0.290 0.000
R00 Abnormalities of heart beat
0.709 0.291 0.000
V10-V19 Pedal cyclist injured in transport accident
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.707 0.293 0.000
M35 Other systemic involvement of connective tissue
0.707 0.293 0.000
Z90.1 Acquired absence of breast(s)
0.707 0.293 0.000
S00.9 Superficial injury of head, part unspecified
0.706 0.294 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.705 0.295 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.705 0.295 0.000
I07 Rheumatic tricuspid valve diseases
0.705 0.295 0.000
I35.0 Aortic (valve) stenosis
0.705 0.295 0.000
J18.1 Lobar pneumonia, unspecified
0.702 0.298 0.000
M54.8 Other dorsalgia
0.702 0.298 0.000
M54.6 Pain in thoracic spine
0.702 0.298 0.000
M54.0 Panniculitis affecting regions of neck and back
0.702 0.298 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.700 0.300 0.000
Z90.5 Acquired absence of kidney
0.699 0.301 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.699 0.301 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.697 0.302 0.000
V20-V29 Motorcycle rider injured in transport accident
0.697 0.303 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.697 0.303 0.000
M77 Other enthesopathies
0.696 0.304 0.000
M76 Enthesopathies of lower limb, excluding foot
0.696 0.304 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.696 0.304 0.000
M71 Other bursopathies
0.696 0.304 0.000
N63 Unspecified lump in breast
0.696 0.304 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.696 0.304 0.000
Y43 Primarily systemic agents
0.695 0.305 0.000
S80 Superficial injury of lower leg
0.695 0.305 0.000
M14 Arthropathies in other diseases classified elsewhere
0.694 0.306 0.000
M12 Other specific arthropathies
0.694 0.306 0.000
M11 Other crystal arthropathies
0.694 0.306 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.694 0.306 0.000
M08 Juvenile arthritis
0.694 0.306 0.000
M07 Psoriatic and enteropathic arthropathies
0.694 0.306 0.000
M05 Seropositive rheumatoid arthritis
0.694 0.306 0.000
I51.6 Cardiovascular disease, unspecified
0.694 0.306 0.000
I51.5 Myocardial degeneration
0.694 0.306 0.000
I51.4 Myocarditis, unspecified
0.694 0.306 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.694 0.306 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.694 0.306 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.694 0.306 0.000
I51.0 Cardiac septal defect, acquired
0.694 0.306 0.000
N21.0 Calculus in bladder
0.694 0.306 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.694 0.306 0.000
J18.9 Pneumonia, unspecified
0.693 0.307 0.000
M51.3 Other specified intervertebral disk degeneration
0.693 0.307 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.693 0.307 0.000
M51.9 Intervertebral disk disorder, unspecified
0.693 0.307 0.000
M51.8 Other specified intervertebral disk disorders
0.693 0.307 0.000
M51.4 Schmorl's nodes
0.693 0.307 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.693 0.307 0.000
H40 Glaucoma
0.691 0.309 0.000
R00.1 Bradycardia, unspecified
0.690 0.310 0.000
N20.1 Calculus of ureter
0.690 0.310 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.689 0.311 0.000
G58 Other mononeuropathies
0.689 0.311 0.000
E40-E46 Malnutrition
0.689 0.311 0.000
I15 Secondary hypertension
0.688 0.312 0.000
I13 Hypertensive heart and renal disease
0.688 0.312 0.000
I11 Hypertensive heart disease
0.688 0.312 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.688 0.312 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.686 0.314 0.000
G70-G73 Diseases of myoneural junction and muscle
0.686 0.314 0.000
G30-G32 Other degenerative diseases of the nervous system
0.686 0.314 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.686 0.314 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.686 0.314 0.000
N17 Acute renal failure
0.686 0.314 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.685 0.315 0.000
Y35-Y36 Legal intervention and operations of war
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.685 0.315 0.000
Y00-Y09 Assault
0.685 0.315 0.000
X85-X99 Assault
0.685 0.315 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.685 0.315 0.000
X50-X57 Overexertion, travel and privation
0.685 0.315 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.685 0.315 0.000
X30-X39 Exposure to forces of nature
0.685 0.315 0.000
X20-X29 Contact with venomous animals and plants
0.685 0.315 0.000
X10-X19 Contact with heat and hot substances
0.685 0.315 0.000
X00-X09 Exposure to smoke, fire and flames
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
W75-W84 Other accidental threats to breathing
0.685 0.315 0.000
W65-W74 Accidental drowning and submersion
0.685 0.315 0.000
W50-W64 Exposure to animate mechanical forces
0.685 0.315 0.000
V98-V99 Other and unspecified transport accidents
0.685 0.315 0.000
V95-V97 Air and space transport accidents
0.685 0.315 0.000
V90-V94 Water transport accidents
0.685 0.315 0.000
V80-V89 Other land transport accidents
0.685 0.315 0.000
V70-V79 Bus occupant injured in transport accident
0.685 0.315 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.685 0.315 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.685 0.315 0.000
V40-V49 Car occupant injured in transport accident
0.685 0.315 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.685 0.315 0.000
V01-V09 Pedestrian injured in transport accident
0.685 0.315 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.683 0.317 0.000
J00 Acute nasopharyngitis [common cold]
0.683 0.317 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.683 0.317 0.000
M34 Systemic sclerosis
0.683 0.317 0.000
M33 Dermatopolymyositis
0.683 0.317 0.000
M32 Systemic lupus erythematosus
0.683 0.317 0.000
M30 Polyarteritis nodosa and related conditions
0.683 0.317 0.000
M21 Other acquired deformities of limbs
0.683 0.317 0.000
I49.4 Other and unspecified premature depolarisation
0.681 0.319 0.000
N19 Unspecified renal failure
0.680 0.320 0.000
M75.5 Bursitis of shoulder
0.679 0.321 0.000
N18.8 Other chronic renal failure
0.679 0.321 0.000
N18.2 Chronic kidney disease, stage 2
0.679 0.321 0.000
N18.1 Chronic kidney disease, stage 1
0.679 0.321 0.000
M46 Other inflammatory spondylopathies
0.678 0.322 0.000
J92.9 Pleural plaque without asbestos
0.676 0.324 0.000
S27 Injury of other and unspecified intrathoracic organs
0.676 0.324 0.000
I42 Cardiomyopathy
0.676 0.324 0.000
G95 Other diseases of spinal cord
0.675 0.325 0.000
I61 Intracerebral haemorrhage
0.675 0.325 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.674 0.326 0.000
I49.5 Sick sinus syndrome
0.674 0.326 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.674 0.326 0.000
H31 Other disorders of choroid
0.674 0.326 0.000
H30 Chorioretinal inflammation
0.674 0.326 0.000
S02 Fracture of skull and facial bones
0.674 0.326 0.000
I25.1 Atherosclerotic heart disease
0.673 0.327 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.673 0.327 0.000
Q60-Q64 Congenital malformations of the urinary system
0.673 0.327 0.000
M25.9 Joint disorder, unspecified
0.672 0.328 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.672 0.328 0.000
M25.3 Other instability of joint
0.672 0.328 0.000
M25.2 Flail joint
0.672 0.328 0.000
M25.1 Fistula of joint
0.672 0.328 0.000
M25.0 Haemarthrosis
0.672 0.328 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.672 0.328 0.000
M75.8 Other shoulder lesions
0.671 0.329 0.000
M75.9 Shoulder lesion, unspecified
0.671 0.329 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.671 0.329 0.000
M50 Cervical disk disorders
0.670 0.329 0.000
J81 Pulmonary oedema
0.670 0.330 0.000
Z98 Other postsurgical states
0.670 0.330 0.000
M49 Spondylopathies in diseases classified elsewhere
0.668 0.331 0.000
Y95 Nosocomial condition
0.668 0.332 0.000
Q23 Congenital malformations of aortic and mitral valves
0.668 0.332 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.666 0.334 0.000
E10.3 With ophthalmic complications
0.665 0.335 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.664 0.336 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.664 0.336 0.000
M54.37 Sciatica (Lumbosacral region)
0.664 0.336 0.000
M54.35 Sciatica (Thoracolumbar region)
0.664 0.336 0.000
M54.34 Sciatica-Thoracic
0.664 0.336 0.000
M54.33 Sciatica-Cervicothoracic
0.664 0.336 0.000
M54.32 Sciatica-Cervical
0.664 0.336 0.000
M54.31 Sciatica-Occipit-atl-axl
0.664 0.336 0.000
M54.30 Sciatica (Multiple sites in spine)
0.664 0.336 0.000
S08 Traumatic amputation of part of head
0.664 0.336 0.000
S07 Crushing injury of head
0.664 0.336 0.000
S06 Intracranial injury
0.664 0.336 0.000
S05 Injury of eye and orbit
0.664 0.336 0.000
S04 Injury of cranial nerves
0.664 0.336 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.664 0.336 0.000
Z60.2 Living alone
0.663 0.337 0.000
E11.4 With neurological complications
0.662 0.338 0.000
Q21.1 Atrial septal defect
0.662 0.338 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.662 0.338 0.000
N60.3 Fibrosclerosis of breast
0.662 0.338 0.000
M25.59 Pain in joint (Site unspecified)
0.661 0.339 0.000
M25.58 Pain in joint (Other)
0.661 0.339 0.000
M25.54 Pain in joint (Hand)
0.661 0.339 0.000
M25.52 Pain in joint (Upper arm)
0.661 0.339 0.000
M22.4 Chondromalacia patellae
0.661 0.339 0.000
I47.1 Supraventricular tachycardia
0.661 0.339 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.660 0.340 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.659 0.341 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.659 0.341 0.000
I49.2 Junctional premature depolarisation
0.657 0.343 0.000
I49.1 Atrial premature depolarisation
0.657 0.343 0.000
I23 Certain current complications following acute myocardial infarction
0.657 0.343 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.657 0.343 0.000
M48.0 Spinal stenosis
0.657 0.343 0.000
I27 Other pulmonary heart diseases
0.656 0.344 0.000
L20-L30 Dermatitis and eczema
0.656 0.344 0.000
G35 Multiple sclerosis
0.655 0.345 0.000
M25.50 Pain in joint (Multiple sites)
0.654 0.346 0.000
E13 Other specified diabetes mellitus
0.654 0.346 0.000
E12 Malnutrition-related diabetes mellitus
0.654 0.346 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.653 0.347 0.000
J80 Adult respiratory distress syndrome
0.653 0.347 0.000
H52 Disorders of refraction and accommodation
0.653 0.347 0.000
J98.1 Pulmonary collapse
0.653 0.347 0.000
N18.4 Chronic kidney disease, stage 4
0.653 0.347 0.000
M75.3 Calcific tendinitis of shoulder
0.653 0.347 0.000
M22.8 Other disorders of patella
0.652 0.348 0.000
M13.8 Other specified arthritis
0.652 0.348 0.000
M13.1 Monoarthritis, not elsewhere classified
0.652 0.348 0.000
M13.0 Polyarthritis, unspecified
0.652 0.348 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.651 0.349 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.650 0.350 0.000
Z99.3 Dependence on wheelchair
0.650 0.350 0.000
M79.0 Rheumatism, unspecified
0.650 0.350 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.650 0.350 0.000
G51 Facial nerve disorders
0.649 0.350 0.000
E00-E07 Disorders of thyroid gland
0.649 0.351 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.649 0.351 0.000
H35.0 Background retinopathy and retinal vascular changes
0.649 0.351 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.648 0.352 0.000
I99 Other and unspecified disorders of circulatory system
0.648 0.352 0.000
N23 Unspecified renal colic
0.647 0.353 0.000
M65 Synovitis and tenosynovitis
0.647 0.353 0.000
I38 Endocarditis, valve unspecified
0.645 0.355 0.000
J17 Pneumonia in diseases classified elsewhere
0.645 0.355 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.645 0.355 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.645 0.355 0.000
J12 Viral pneumonia, not elsewhere classified
0.645 0.355 0.000
J11 Influenza, virus not identified
0.645 0.355 0.000
J10 Influenza due to identified influenza virus
0.645 0.355 0.000
J14 Pneumonia due to Haemophilus influenzae
0.645 0.355 0.000
J09 Influenza due to certain identified influenza virus
0.645 0.355 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.644 0.355 0.000
Q80-Q89 Other congenital malformations
0.644 0.355 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.644 0.355 0.000
Q50-Q56 Congenital malformations of genital organs
0.644 0.355 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.644 0.355 0.000
Q35-Q37 Cleft lip and cleft palate
0.644 0.355 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.644 0.355 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.644 0.355 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.355 0.000
M25.4 Effusion of joint
0.644 0.356 0.000
I46 Cardiac arrest
0.644 0.356 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.643 0.357 0.000
S82.1 Fracture of upper end of tibia
0.643 0.357 0.000
J03 Acute tonsillitis
0.643 0.357 0.000
G54 Nerve root and plexus disorders
0.642 0.358 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.642 0.358 0.000
G52 Disorders of other cranial nerves
0.642 0.358 0.000
S89 Other and unspecified injuries of lower leg
0.641 0.359 0.000
S88 Traumatic amputation of lower leg
0.641 0.359 0.000
S87 Crushing injury of lower leg
0.641 0.359 0.000
S86 Injury of muscle and tendon at lower leg level
0.641 0.359 0.000
S85 Injury of blood vessels at lower leg level
0.641 0.359 0.000
S84 Injury of nerves at lower leg level
0.641 0.359 0.000
S81 Open wound of lower leg
0.641 0.359 0.000
W19 Unspecified fall
0.641 0.359 0.000
M79.6 Pain in limb
0.641 0.359 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.640 0.360 0.000
J96 Respiratory failure, not elsewhere classified
0.640 0.360 0.000
E10.1 With ketoacidosis
0.640 0.360 0.000
N20.2 Calculus of kidney with calculus of ureter
0.640 0.360 0.000
M31 Other necrotising vasculopathies
0.639 0.361 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.639 0.361 0.000
S82.5 Fracture of medial malleolus
0.639 0.361 0.000
E20-E35 Disorders of other endocrine glands
0.638 0.362 0.000
I34 Nonrheumatic mitral valve disorders
0.638 0.362 0.000
H54.7 Unspecified visual loss
0.637 0.362 0.000
M13.98 Arthritis, unspecified (Other)
0.637 0.363 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.637 0.363 0.000
S01.3 Open wound of ear
0.636 0.364 0.000
H40.9 Glaucoma, unspecified
0.636 0.364 0.000
I21 Acute myocardial infarction
0.636 0.364 0.000
H57 Other disorders of eye and adnexa
0.636 0.364 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.636 0.364 0.000
J90 Pleural effusion, not elsewhere classified
0.636 0.364 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.636 0.364 0.000
H35.9 Retinal disorder, unspecified
0.635 0.365 0.000
H35.7 Separation of retinal layers
0.635 0.365 0.000
H35.6 Retinal haemorrhage
0.635 0.365 0.000
H35.5 Hereditary retinal dystrophy
0.635 0.365 0.000
H35.4 Peripheral retinal degeneration
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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