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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs140959648
log Bayes Factor = 22.6332
Chromosome 18   position 59,005,176  (GRCh37) Explore rs140959648 on Ensembl!
Variant rs140959648 is part of Cluster X0051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
I21.9 Acute myocardial infarction, unspecified
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
B95-B98 Bacterial, viral and other infectious agents
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
E11 Non-insulin-dependent diabetes mellitus
0.987 0.013 0.000
I25 Chronic ischaemic heart disease
0.985 0.015 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.985 0.015 0.000
Chapter VIII Diseases of the ear and mastoid process
0.979 0.021 0.000
I47 Paroxysmal tachycardia
0.979 0.021 0.000
I60-I69 Cerebrovascular diseases
0.974 0.026 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
E11.9 Without complications
0.973 0.027 0.000
Chapter XXI Factors influencing health status and contact with health services
0.971 0.029 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.970 0.030 0.000
Chapter V Mental and behavioural disorders
0.969 0.031 0.000
Chapter II Neoplasms
0.967 0.033 0.000
G90-G99 Other disorders of the nervous system
0.965 0.035 0.000
H90-H95 Other disorders of ear
0.965 0.035 0.000
T81 Complications of procedures, not elsewhere classified
0.964 0.036 0.000
E00-E07 Disorders of thyroid gland
0.959 0.041 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.958 0.042 0.000
D10-D36 Benign neoplasms
0.956 0.044 0.000
I47.2 Ventricular tachycardia
0.956 0.044 0.000
M50-M54 Other dorsopathies
0.955 0.045 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.951 0.049 0.000
I49 Other cardiac arrhythmias
0.948 0.052 0.000
Chapter X Diseases of the respiratory system
0.948 0.052 0.000
J40-J47 Chronic lower respiratory diseases
0.942 0.058 0.000
E03 Other hypothyroidism
0.940 0.060 0.000
M15-M19 Arthrosis
0.940 0.060 0.000
Chapter XI Diseases of the digestive system
0.939 0.061 0.000
D17 Benign lipomatous neoplasm
0.937 0.063 0.000
G93 Other disorders of brain
0.936 0.064 0.000
I46 Cardiac arrest
0.933 0.067 0.000
E03.9 Hypothyroidism, unspecified
0.927 0.073 0.000
H91 Other hearing loss
0.925 0.075 0.000
M17 Gonarthrosis [arthrosis of knee]
0.925 0.075 0.000
S00-S09 Injuries to the head
0.920 0.080 0.000
D23 Other benign neoplasms of skin
0.918 0.082 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.914 0.086 0.000
I25.2 Old myocardial infarction
0.913 0.087 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.911 0.089 0.000
H40-H42 Glaucoma
0.909 0.091 0.000
O60-O75 Complications of labour and delivery
0.907 0.093 0.000
I73 Other peripheral vascular diseases
0.906 0.094 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.902 0.098 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.900 0.100 0.000
K90-K93 Other diseases of the digestive system
0.900 0.100 0.000
I46.0 Cardiac arrest with successful resuscitation
0.899 0.101 0.000
H91.9 Hearing loss, unspecified
0.897 0.103 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.897 0.103 0.000
H90 Conductive and sensorineural hearing loss
0.895 0.105 0.000
H25-H28 Disorders of lens
0.895 0.105 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.894 0.106 0.000
J44 Other chronic obstructive pulmonary disease
0.888 0.112 0.000
M45-M49 Spondylopathies
0.888 0.112 0.000
M17.1 Other primary gonarthrosis
0.888 0.112 0.000
K70-K77 Diseases of liver
0.888 0.112 0.000
G93.3 Postviral fatigue syndrome
0.884 0.116 0.000
I73.9 Peripheral vascular disease, unspecified
0.884 0.116 0.000
M17.0 Primary gonarthrosis, bilateral
0.884 0.116 0.000
E20-E35 Disorders of other endocrine glands
0.883 0.117 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.883 0.117 0.000
F30-F39 Mood [affective] disorders
0.881 0.119 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.879 0.121 0.000
J43 Emphysema
0.878 0.122 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.876 0.124 0.000
I42 Cardiomyopathy
0.874 0.126 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.871 0.129 0.000
S01 Open wound of head
0.869 0.131 0.000
H43-H45 Disorders of vitreous body and globe
0.868 0.132 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.865 0.135 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.862 0.138 0.000
E10 Insulin-dependent diabetes mellitus
0.860 0.140 0.000
I49.0 Ventricular fibrillation and flutter
0.859 0.141 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.856 0.144 0.000
H40 Glaucoma
0.852 0.148 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.851 0.149 0.000
K90 Intestinal malabsorption
0.850 0.150 0.000
I69 Sequelae of cerebrovascular disease
0.849 0.151 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.848 0.152 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.847 0.153 0.000
I25.1 Atherosclerotic heart disease
0.842 0.158 0.000
G91 Hydrocephalus
0.842 0.158 0.000
M80-M85 Disorders of bone density and structure
0.842 0.158 0.000
K55-K64 Other diseases of intestines
0.841 0.159 0.000
I50 Heart failure
0.841 0.159 0.000
M54 Dorsalgia
0.841 0.159 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.838 0.162 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.836 0.164 0.000
E11.4 With neurological complications
0.835 0.165 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.835 0.165 0.000
S80-S89 Injuries to the knee and lower leg
0.834 0.166 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.834 0.166 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.832 0.168 0.000
J43.9 Emphysema, unspecified
0.832 0.168 0.000
M60-M63 Disorders of muscles
0.830 0.170 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.829 0.171 0.000
J46 Status asthmaticus
0.828 0.172 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.826 0.174 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.824 0.176 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.823 0.177 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.820 0.180 0.000
K60 Fissure and fistula of anal and rectal regions
0.818 0.182 0.000
E50-E64 Other nutritional deficiencies
0.818 0.182 0.000
M50 Cervical disk disorders
0.818 0.182 0.000
I61 Intracerebral haemorrhage
0.817 0.183 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
B25-B34 Other viral diseases
0.816 0.184 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.816 0.184 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.815 0.184 0.000
K90.0 Coeliac disease
0.815 0.185 0.000
D23.0 Skin of lip
0.814 0.186 0.000
K70 Alcoholic liver disease
0.813 0.187 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.812 0.188 0.000
E11.2 With renal complications
0.811 0.189 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.810 0.190 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.806 0.194 0.000
H40.0 Glaucoma suspect
0.806 0.194 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.805 0.195 0.000
J40 Bronchitis, not specified as acute or chronic
0.804 0.196 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.803 0.197 0.000
S70-S79 Injuries to the hip and thigh
0.802 0.198 0.000
D00-D09 In situ neoplasms
0.802 0.198 0.000
I47.1 Supraventricular tachycardia
0.800 0.200 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.800 0.200 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.800 0.200 0.000
T92 Sequelae of injuries of upper limb
0.798 0.202 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.798 0.202 0.000
I65.2 Occlusion and stenosis of carotid artery
0.797 0.203 0.000
G95 Other diseases of spinal cord
0.797 0.203 0.000
X20-X29 Contact with venomous animals and plants
0.796 0.204 0.000
I36 Nonrheumatic tricuspid valve disorders
0.795 0.205 0.000
E10.9 Without complications
0.795 0.205 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.794 0.206 0.000
A00-A09 Intestinal infectious diseases
0.793 0.207 0.000
Y52 Agents primarily affecting the cardiovascular system
0.793 0.207 0.000
O80-O84 Delivery
0.792 0.208 0.000
D23.2 Skin of ear and external auricular canal
0.792 0.208 0.000
S20-S29 Injuries to the thorax
0.791 0.209 0.000
E11.0 With coma
0.791 0.209 0.000
D34 Benign neoplasm of thyroid gland
0.791 0.209 0.000
D36 Benign neoplasm of other and unspecified sites
0.791 0.209 0.000
I49.5 Sick sinus syndrome
0.788 0.212 0.000
O70 Perineal laceration during delivery
0.787 0.213 0.000
O62 Abnormalities of forces of labour
0.784 0.216 0.000
E22 Hyperfunction of pituitary gland
0.783 0.217 0.000
D23.6 Skin of upper limb, including shoulder
0.782 0.217 0.000
I77 Other disorders of arteries and arterioles
0.782 0.218 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.781 0.219 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.780 0.220 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.779 0.221 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.778 0.222 0.000
H26 Other cataract
0.778 0.222 0.000
J45 Asthma
0.776 0.223 0.000
D13.2 Duodenum
0.776 0.224 0.000
I30 Acute pericarditis
0.774 0.226 0.000
S02 Fracture of skull and facial bones
0.772 0.228 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.772 0.228 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.772 0.228 0.000
K60.3 Anal fistula
0.772 0.228 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.771 0.229 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.771 0.229 0.000
M51 Other intervertebral disk disorders
0.771 0.229 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.771 0.229 0.000
I72 Other aneurysm
0.769 0.231 0.000
G30-G32 Other degenerative diseases of the nervous system
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.765 0.235 0.000
M47 Spondylosis
0.764 0.235 0.000
Z87 Personal history of other diseases and conditions
0.764 0.236 0.000
D23.3 Skin of other and unspecified parts of face
0.763 0.237 0.000
T87 Complications peculiar to reattachment and amputation
0.763 0.237 0.000
M65-M68 Disorders of synovium and tendon
0.762 0.238 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.762 0.238 0.000
F32 Depressive episode
0.761 0.239 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.761 0.239 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.759 0.241 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
I45 Other conduction disorders
0.759 0.241 0.000
Y43 Primarily systemic agents
0.759 0.241 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.758 0.242 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.758 0.242 0.000
I63 Cerebral infarction
0.757 0.243 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.756 0.244 0.000
Chapter XXII Codes for special purposes
0.755 0.245 0.000
G91.9 Hydrocephalus, unspecified
0.754 0.246 0.000
H25 Senile cataract
0.751 0.249 0.000
S01.8 Open wound of other parts of head
0.750 0.250 0.000
H43 Disorders of vitreous body
0.750 0.250 0.000
I31 Other diseases of pericardium
0.750 0.250 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.750 0.250 0.000
H90.5 Sensorineural hearing loss, unspecified
0.749 0.251 0.000
Y44 Agents primarily affecting blood constituents
0.748 0.251 0.000
D23.5 Skin of trunk
0.748 0.252 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.748 0.252 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.748 0.252 0.000
I05-I09 Chronic rheumatic heart diseases
0.747 0.253 0.000
I70 Atherosclerosis
0.746 0.254 0.000
G93.9 Disorder of brain, unspecified
0.746 0.254 0.000
H90.3 Sensorineural hearing loss, bilateral
0.746 0.254 0.000
I49.3 Ventricular premature depolarisation
0.745 0.255 0.000
O72 Postpartum haemorrhage
0.745 0.255 0.000
M53 Other dorsopathies, not elsewhere classified
0.744 0.256 0.000
H55-H59 Other disorders of eye and adnexa
0.743 0.257 0.000
O36 Maternal care for other known or suspected foetal problems
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
H90.0 Conductive hearing loss, bilateral
0.741 0.259 0.000
Z72 Problems related to lifestyle
0.741 0.259 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.739 0.261 0.000
H60-H62 Diseases of external ear
0.739 0.261 0.000
I25.3 Aneurysm of heart
0.738 0.262 0.000
E11.5 With peripheral circulatory complications
0.737 0.263 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.736 0.263 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.736 0.264 0.000
I60 Subarachnoid haemorrhage
0.736 0.264 0.000
Z22 Carrier of infectious disease
0.735 0.265 0.000
T93 Sequelae of injuries of lower limb
0.734 0.265 0.000
S90-S99 Injuries to the ankle and foot
0.734 0.266 0.000
D13.1 Stomach
0.734 0.266 0.000
I78 Diseases of capillaries
0.734 0.266 0.000
T86 Failure and rejection of transplanted organs and tissues
0.732 0.268 0.000
G93.6 Cerebral oedema
0.732 0.268 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.732 0.268 0.000
X60-X84 Intentional self-harm
0.731 0.268 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.731 0.269 0.000
I20 Angina pectoris
0.731 0.269 0.000
T66-T78 Other and unspecified effects of external causes
0.730 0.270 0.000
I62 Other nontraumatic intracranial haemorrhage
0.730 0.270 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.730 0.270 0.000
I49.9 Cardiac arrhythmia, unspecified
0.729 0.271 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.729 0.271 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.729 0.271 0.000
O63 Long labour
0.729 0.271 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.727 0.272 0.000
I42.2 Other hypertrophic cardiomyopathy
0.727 0.273 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.727 0.273 0.000
K55 Vascular disorders of intestine
0.727 0.273 0.000
W20-W49 Exposure to inanimate mechanical forces
0.727 0.273 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.726 0.274 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.726 0.274 0.000
M54.3 Sciatica
0.725 0.275 0.000
S01.1 Open wound of eyelid and periocular area
0.725 0.275 0.000
I74 Arterial embolism and thrombosis
0.724 0.276 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.723 0.277 0.000
V80-V89 Other land transport accidents
0.722 0.277 0.000
I25.5 Ischaemic cardiomyopathy
0.722 0.278 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.722 0.278 0.000
Z74 Problems related to care-provider dependency
0.721 0.278 0.000
F10.1 Harmful use
0.721 0.279 0.000
K35-K38 Diseases of appendix
0.721 0.279 0.000
H10-H13 Disorders of conjunctiva
0.720 0.280 0.000
T88.5 Other complications of anaesthesia
0.720 0.280 0.000
H65-H75 Diseases of middle ear and mastoid
0.718 0.282 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.718 0.282 0.000
G70-G73 Diseases of myoneural junction and muscle
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I10-I15 Hypertensive diseases
0.716 0.284 0.000
H93 Other disorders of ear, not elsewhere classified
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
K60.2 Anal fissure, unspecified
0.716 0.284 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.716 0.284 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I33 Acute and subacute endocarditis
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
C15-C26 Malignant neoplasms of digestive organs
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
B15-B19 Viral hepatitis
0.715 0.285 0.000
E53 Deficiency of other B group vitamins
0.715 0.285 0.000
O42 Premature rupture of membranes
0.715 0.285 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.713 0.286 0.000
B99-B99 Other infectious diseases
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
M54.1 Radiculopathy
0.712 0.288 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.711 0.288 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.711 0.289 0.000
E13 Other specified diabetes mellitus
0.711 0.289 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.711 0.289 0.000
G93.8 Other specified disorders of brain
0.710 0.290 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.710 0.290 0.000
M62 Other disorders of muscle
0.709 0.290 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.709 0.291 0.000
M19 Other arthrosis
0.709 0.291 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
E11.8 With unspecified complications
0.707 0.293 0.000
E11.7 With multiple complications
0.707 0.293 0.000
E11.6 With other specified complications
0.707 0.293 0.000
E11.1 With ketoacidosis
0.707 0.293 0.000
D26 Other benign neoplasms of uterus
0.707 0.293 0.000
Z71.8 Other specified counselling
0.707 0.293 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.707 0.293 0.000
O70.1 Second degree perineal laceration during delivery
0.707 0.293 0.000
I25.6 Silent myocardial ischaemia
0.706 0.293 0.000
I25.4 Coronary artery aneurysm
0.706 0.293 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.706 0.293 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.706 0.293 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.706 0.293 0.000
I42.0 Dilated cardiomyopathy
0.706 0.294 0.000
I34 Nonrheumatic mitral valve disorders
0.705 0.295 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.704 0.296 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.704 0.296 0.000
H53-H54 Visual disturbances and blindness
0.704 0.296 0.000
M46 Other inflammatory spondylopathies
0.703 0.297 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.703 0.297 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.703 0.297 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.702 0.298 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.702 0.298 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.702 0.298 0.000
I47.0 Reentry ventricular arrhythmia
0.702 0.298 0.000
M45 Ankylosing spondylitis
0.701 0.299 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.699 0.301 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
T90 Sequelae of injuries of head
0.699 0.301 0.000
J81 Pulmonary oedema
0.699 0.301 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.698 0.302 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.698 0.302 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.698 0.302 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.698 0.302 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.695 0.304 0.000
O62.2 Other uterine inertia
0.695 0.305 0.000
M50.3 Other cervical disk degeneration
0.695 0.305 0.000
F40 Phobic anxiety disorders
0.695 0.305 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.694 0.306 0.000
F70-F79 Mental retardation
0.694 0.306 0.000
F60-F69 Disorders of adult personality and behaviour
0.694 0.306 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.694 0.306 0.000
S01.5 Open wound of lip and oral cavity
0.694 0.306 0.000
F30 Manic episode
0.694 0.306 0.000
H40.8 Other glaucoma
0.693 0.306 0.000
W00-W19 Falls
0.693 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
I50.1 Left ventricular failure
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.693 0.307 0.000
S06 Intracranial injury
0.693 0.307 0.000
M70-M79 Other soft tissue disorders
0.693 0.307 0.000
J45.0 Predominantly allergic asthma
0.693 0.307 0.000
E65-E68 Obesity and other hyperalimentation
0.693 0.307 0.000
E07 Other disorders of thyroid
0.693 0.307 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.692 0.308 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.692 0.308 0.000
G90 Disorders of autonomic nervous system
0.692 0.308 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.692 0.308 0.000
G92 Toxic encephalopathy
0.692 0.308 0.000
D23.4 Skin of scalp and neck
0.692 0.308 0.000
V10-V19 Pedal cyclist injured in transport accident
0.692 0.308 0.000
D06 Carcinoma in situ of cervix uteri
0.692 0.308 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.692 0.308 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.692 0.308 0.000
T81.9 Unspecified complication of procedure
0.691 0.309 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.691 0.309 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.691 0.309 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.691 0.309 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.691 0.309 0.000
L40-L45 Papulosquamous disorders
0.691 0.309 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.691 0.309 0.000
J20-J22 Other acute lower respiratory infections
0.691 0.309 0.000
L90 Atrophic disorders of skin
0.690 0.310 0.000
F80-F89 Disorders of psychological development
0.689 0.311 0.000
I61.8 Other intracerebral haemorrhage
0.688 0.312 0.000
B34 Viral infection of unspecified site
0.688 0.312 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.688 0.312 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.688 0.312 0.000
K75 Other inflammatory liver diseases
0.688 0.312 0.000
E06 Thyroiditis
0.687 0.313 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.687 0.313 0.000
E00 Congenital iodine-deficiency syndrome
0.687 0.313 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.687 0.313 0.000
H44 Disorders of globe
0.687 0.313 0.000
O85-O92 Complications predominantly related to the puerperium
0.687 0.313 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
I77.1 Stricture of artery
0.687 0.313 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.686 0.314 0.000
K76 Other diseases of liver
0.686 0.314 0.000
D27 Benign neoplasm of ovary
0.686 0.314 0.000
D31 Benign neoplasm of eye and adnexa
0.686 0.314 0.000
D30 Benign neoplasm of urinary organs
0.686 0.314 0.000
D29 Benign neoplasm of male genital organs
0.686 0.314 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.686 0.314 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.686 0.314 0.000
D19 Benign neoplasm of mesothelial tissue
0.686 0.314 0.000
D16 Benign neoplasm of bone and articular cartilage
0.686 0.314 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.686 0.314 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.686 0.314 0.000
D10 Benign neoplasm of mouth and pharynx
0.686 0.314 0.000
K70.9 Alcoholic liver disease, unspecified
0.685 0.315 0.000
O41 Other disorders of amniotic fluid and membranes
0.685 0.315 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.682 0.318 0.000
Y58 Bacterial vaccines
0.682 0.318 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.318 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.682 0.318 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.682 0.318 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.682 0.318 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.682 0.318 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.682 0.318 0.000
Y48 Anaesthetics and therapeutic gases
0.682 0.318 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.682 0.318 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.681 0.318 0.000
G96 Other disorders of central nervous system
0.681 0.319 0.000
Z72.0 Tobacco use
0.681 0.319 0.000
I38 Endocarditis, valve unspecified
0.680 0.319 0.000
I49.2 Junctional premature depolarisation
0.680 0.320 0.000
I49.1 Atrial premature depolarisation
0.680 0.320 0.000
F31 Bipolar affective disorder
0.680 0.320 0.000
I49.8 Other specified cardiac arrhythmias
0.679 0.321 0.000
F99-F99 Unspecified mental disorder
0.678 0.322 0.000
Z88.6 Personal history of allergy to analgesic agent
0.678 0.322 0.000
E04 Other non-toxic goitre
0.678 0.322 0.000
F10.2 Dependence syndrome
0.677 0.323 0.000
G95.2 Cord compression, unspecified
0.677 0.323 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.677 0.323 0.000
K72 Hepatic failure, not elsewhere classified
0.677 0.323 0.000
H25.8 Other senile cataract
0.676 0.324 0.000
M86-M90 Other osteopathies
0.676 0.324 0.000
J41 Simple and mucopurulent chronic bronchitis
0.676 0.324 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.674 0.326 0.000
J42 Unspecified chronic bronchitis
0.674 0.326 0.000
J60-J70 Lung diseases due to external agents
0.674 0.326 0.000
E03.8 Other specified hypothyroidism
0.674 0.326 0.000
E03.5 Myxoedema coma
0.674 0.326 0.000
E03.4 Atrophy of thyroid (acquired)
0.674 0.326 0.000
E03.3 Postinfectious hypothyroidism
0.674 0.326 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.674 0.326 0.000
E03.1 Congenital hypothyroidism without goitre
0.674 0.326 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.674 0.326 0.000
M15 Polyarthrosis
0.674 0.326 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.673 0.327 0.000
I71 Aortic aneurysm and dissection
0.673 0.327 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.673 0.327 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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