TreeWAS – Variant ID: rs141480664

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	0.979	0.021	0.000
I44 Atrioventricular and left bundle-branch block	0.977	0.023	0.000
I44.7 Left bundle-branch block, unspecified	0.963	0.037	0.000
Chapter IX Diseases of the circulatory system	0.959	0.041	0.000
I35 Nonrheumatic aortic valve disorders	0.957	0.043	0.000
I20-I25 Ischaemic heart diseases	0.942	0.058	0.000
I44.0 Atrioventricular block, first degree	0.928	0.072	0.000
I21 Acute myocardial infarction	0.921	0.079	0.000
I35.1 Aortic (valve) insufficiency	0.902	0.098	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.900	0.100	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.874	0.126	0.000
I50 Heart failure	0.869	0.131	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.860	0.140	0.000
I51 Complications and ill-defined descriptions of heart disease	0.832	0.168	0.000
I25 Chronic ischaemic heart disease	0.830	0.170	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.824	0.176	0.000
I50.9 Heart failure, unspecified	0.824	0.176	0.000
I22 Subsequent myocardial infarction	0.818	0.182	0.000
I05-I09 Chronic rheumatic heart diseases	0.810	0.190	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.808	0.192	0.000
I49 Other cardiac arrhythmias	0.799	0.201	0.000
I44.3 Other and unspecified atrioventricular block	0.796	0.204	0.000
I44.1 Atrioventricular block, second degree	0.787	0.213	0.000
I46 Cardiac arrest	0.783	0.217	0.000
I51.9 Heart disease, unspecified	0.776	0.224	0.000
I25.2 Old myocardial infarction	0.759	0.241	0.000
I38 Endocarditis, valve unspecified	0.741	0.259	0.000
I77 Other disorders of arteries and arterioles	0.741	0.259	0.000
I35.8 Other aortic valve disorders	0.726	0.274	0.000
I21.4 Acute subendocardial myocardial infarction	0.725	0.275	0.000
I95 Hypotension	0.721	0.279	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.720	0.279	0.000
I73 Other peripheral vascular diseases	0.720	0.280	0.000
I33 Acute and subacute endocarditis	0.709	0.290	0.000
I52 Other heart disorders in diseases classified elsewhere	0.702	0.298	0.000
I48 Atrial fibrillation and flutter	0.702	0.298	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.702	0.298	0.000
I41 Myocarditis in diseases classified elsewhere	0.702	0.298	0.000
I40 Acute myocarditis	0.702	0.298	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.702	0.298	0.000
I37 Pulmonary valve disorders	0.702	0.298	0.000
I36 Nonrheumatic tricuspid valve disorders	0.702	0.298	0.000
I32 Pericarditis in diseases classified elsewhere	0.702	0.298	0.000
I30 Acute pericarditis	0.702	0.298	0.000
I44.6 Other and unspecified fascicular block	0.700	0.300	0.000
I44.5 Left posterior fascicular block	0.700	0.300	0.000
I44.4 Left anterior fascicular block	0.700	0.300	0.000
I70 Atherosclerosis	0.695	0.305	0.000
I00-I02 Acute rheumatic fever	0.688	0.312	0.000
I49.0 Ventricular fibrillation and flutter	0.687	0.313	0.000
I35.9 Aortic valve disorder, unspecified	0.686	0.314	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.686	0.314	0.000
I31 Other diseases of pericardium	0.678	0.322	0.000
I23 Certain current complications following acute myocardial infarction	0.675	0.324	0.000
I25.5 Ischaemic cardiomyopathy	0.671	0.329	0.000
I35.0 Aortic (valve) stenosis	0.669	0.331	0.000
I25.1 Atherosclerotic heart disease	0.668	0.332	0.000
I08 Multiple valve diseases	0.664	0.336	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.660	0.340	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.660	0.340	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.660	0.340	0.000
I71 Aortic aneurysm and dissection	0.655	0.345	0.000
I73.9 Peripheral vascular disease, unspecified	0.653	0.346	0.000
I34 Nonrheumatic mitral valve disorders	0.652	0.348	0.000
I50.0 Congestive heart failure	0.647	0.353	0.000
I49.3 Ventricular premature depolarisation	0.639	0.360	0.000
I42 Cardiomyopathy	0.639	0.361	0.000
I24 Other acute ischaemic heart diseases	0.637	0.363	0.000
I46.9 Cardiac arrest, unspecified	0.633	0.367	0.000
I07 Rheumatic tricuspid valve diseases	0.625	0.375	0.000
I45 Other conduction disorders	0.619	0.381	0.000
I84 Haemorrhoids	0.619	0.381	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.616	0.384	0.000
I72 Other aneurysm	0.615	0.385	0.000
I49.1 Atrial premature depolarisation	0.611	0.389	0.000
I95.1 Orthostatic hypotension	0.611	0.389	0.000
I99 Other and unspecified disorders of circulatory system	0.607	0.393	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.607	0.393	0.000
I84.2 Internal haemorrhoids without complication	0.606	0.394	0.000
I05 Rheumatic mitral valve diseases	0.603	0.397	0.000
I44.2 Atrioventricular block, complete	0.599	0.401	0.000
I51.6 Cardiovascular disease, unspecified	0.596	0.403	0.000
I51.5 Myocardial degeneration	0.596	0.403	0.000
I51.4 Myocarditis, unspecified	0.596	0.403	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.596	0.403	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.596	0.403	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.596	0.403	0.000
I51.0 Cardiac septal defect, acquired	0.596	0.403	0.000
I25.6 Silent myocardial ischaemia	0.595	0.404	0.000
I25.4 Coronary artery aneurysm	0.595	0.404	0.000
I25.3 Aneurysm of heart	0.595	0.404	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.595	0.404	0.000
I77.8 Other specified disorders of arteries and arterioles	0.594	0.406	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.591	0.409	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.591	0.409	0.000
I22.8 Subsequent myocardial infarction of other sites	0.586	0.413	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.586	0.413	0.000
I09 Other rheumatic heart diseases	0.581	0.419	0.000
I06 Rheumatic aortic valve diseases	0.581	0.419	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.580	0.420	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.577	0.423	0.000
I46.0 Cardiac arrest with successful resuscitation	0.576	0.424	0.000
I77.1 Stricture of artery	0.574	0.426	0.000
I49.2 Junctional premature depolarisation	0.573	0.427	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.566	0.434	0.000
I51.8 Other ill-defined heart diseases	0.563	0.437	0.000
I95.2 Hypotension due to drugs	0.562	0.438	0.000
I46.1 Sudden cardiac death, so described	0.561	0.438	0.000
I10-I15 Hypertensive diseases	0.558	0.442	0.000
I49.5 Sick sinus syndrome	0.551	0.448	0.000
I84.8 Unspecified haemorrhoids with other complications	0.551	0.449	0.000
I47 Paroxysmal tachycardia	0.550	0.450	0.000
I78 Diseases of capillaries	0.545	0.455	0.000
I95.9 Hypotension, unspecified	0.543	0.457	0.000
I77.6 Arteritis, unspecified	0.541	0.459	0.000
I49.9 Cardiac arrhythmia, unspecified	0.540	0.460	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.539	0.461	0.000
# Top node	0.533	0.467	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.533	0.467	0.000
I77.5 Necrosis of artery	0.531	0.469	0.000
I77.4 Coeliac artery compression syndrome	0.531	0.469	0.000
I77.3 Arterial fibromuscular dysplasia	0.531	0.469	0.000
I77.2 Rupture of artery	0.531	0.469	0.000
I77.0 Arteriovenous fistula, acquired	0.531	0.469	0.000
S60-S69 Injuries to the wrist and hand	0.527	0.473	0.000
I49.4 Other and unspecified premature depolarisation	0.524	0.476	0.000
I31.9 Disease of pericardium, unspecified	0.519	0.481	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.518	0.481	0.000
I74 Arterial embolism and thrombosis	0.517	0.482	0.000
I33.0 Acute and subacute infective endocarditis	0.517	0.483	0.000
I95.8 Other hypotension	0.517	0.483	0.000
I95.0 Idiopathic hypotension	0.517	0.483	0.000
I73.8 Other specified peripheral vascular diseases	0.516	0.484	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.516	0.484	0.000
I45.3 Trifascicular block	0.515	0.484	0.000
I82 Other venous embolism and thrombosis	0.513	0.487	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.509	0.490	0.000
I33.9 Acute endocarditis, unspecified	0.509	0.491	0.000
I49.8 Other specified cardiac arrhythmias	0.508	0.492	0.000
I84.3 External thrombosed haemorrhoids	0.503	0.497	0.000
I30.9 Acute pericarditis, unspecified	0.503	0.497	0.000
I30.8 Other forms of acute pericarditis	0.503	0.497	0.000
I30.1 Infective pericarditis	0.503	0.497	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.503	0.497	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.503	0.497	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.503	0.497	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.503	0.497	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.503	0.497	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.503	0.497	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.503	0.497	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.503	0.497	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.503	0.497	0.000
I37.9 Pulmonary valve disorder, unspecified	0.503	0.497	0.000
I37.8 Other pulmonary valve disorders	0.503	0.497	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.503	0.497	0.000
I37.1 Pulmonary valve insufficiency	0.503	0.497	0.000
I37.0 Pulmonary valve stenosis	0.503	0.497	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.503	0.497	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.503	0.497	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.503	0.497	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.503	0.497	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.503	0.497	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.503	0.497	0.000
I40.9 Acute myocarditis, unspecified	0.503	0.497	0.000
I40.8 Other acute myocarditis	0.503	0.497	0.000
I40.1 Isolated myocarditis	0.503	0.497	0.000
I40.0 Infective myocarditis	0.503	0.497	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.503	0.497	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.503	0.497	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.503	0.497	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.503	0.497	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.503	0.497	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.503	0.497	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.503	0.497	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.503	0.497	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.503	0.497	0.000
I48.4 Atypical atrial flutter	0.503	0.497	0.000
I48.3 Typical atrial flutter	0.503	0.497	0.000
I48.2 Chronic atrial fibrillation	0.503	0.497	0.000
I48.1 Persistent atrial fibrillation	0.503	0.497	0.000
I48.0 Paroxysmal atrial fibrillation	0.503	0.497	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.503	0.497	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.503	0.497	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.503	0.497	0.000
Chapter II Neoplasms	0.503	0.497	0.000
I70.9 Generalised and unspecified atherosclerosis	0.498	0.501	0.000
I70.8 Atherosclerosis of other arteries	0.498	0.501	0.000
I70.1 Atherosclerosis of renal artery	0.498	0.501	0.000
I70.0 Atherosclerosis of aorta	0.498	0.501	0.000
Chapter XX External causes of morbidity and mortality	0.496	0.504	0.000
I02 Rheumatic chorea	0.493	0.507	0.000
I01 Rheumatic fever with heart involvement	0.493	0.507	0.000
I00 Rheumatic fever without mention of heart involvement	0.493	0.507	0.000
I07.1 Tricuspid insufficiency	0.493	0.507	0.000
I84.4 External haemorrhoids with other complications	0.493	0.507	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.493	0.507	0.000
I88 Nonspecific lymphadenitis	0.492	0.508	0.000
I81 Portal vein thrombosis	0.492	0.508	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.491	0.509	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.490	0.510	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.489	0.511	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.489	0.511	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.487	0.513	0.000
I31.8 Other specified diseases of pericardium	0.486	0.514	0.000
I31.2 Haemopericardium, not elsewhere classified	0.486	0.514	0.000
I31.1 Chronic constrictive pericarditis	0.486	0.514	0.000
I31.0 Chronic adhesive pericarditis	0.486	0.514	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.486	0.514	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.486	0.514	0.000
I23.8 Other current complications following acute myocardial infarction	0.484	0.515	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.484	0.515	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.484	0.515	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.484	0.515	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.484	0.515	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.484	0.515	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.484	0.515	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.484	0.515	0.000
I34.0 Mitral (valve) insufficiency	0.480	0.520	0.000
S62 Fracture at wrist and hand level	0.479	0.521	0.000
I86 Varicose veins of other sites	0.479	0.521	0.000
I87 Other disorders of veins	0.479	0.521	0.000
I42.9 Cardiomyopathy, unspecified	0.477	0.523	0.000
I08.9 Multiple valve disease, unspecified	0.476	0.524	0.000
I08.8 Other multiple valve diseases	0.476	0.524	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.476	0.524	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.476	0.524	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.475	0.525	0.000
C44 Other malignant neoplasms of skin	0.473	0.527	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.473	0.527	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.472	0.528	0.000
I84.0 Internal thrombosed haemorrhoids	0.471	0.529	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.469	0.530	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.469	0.530	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.469	0.530	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.469	0.530	0.000
I71.0 Dissection of aorta [any part]	0.469	0.530	0.000
I85 Oesophageal varices	0.468	0.532	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.468	0.532	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.468	0.532	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.468	0.532	0.000
Chapter VI Diseases of the nervous system	0.464	0.536	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.463	0.537	0.000
I45.9 Conduction disorder, unspecified	0.461	0.538	0.000
I42.2 Other hypertrophic cardiomyopathy	0.458	0.541	0.000
I42.8 Other cardiomyopathies	0.458	0.542	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.458	0.542	0.000
I42.6 Alcoholic cardiomyopathy	0.458	0.542	0.000
I42.5 Other restrictive cardiomyopathy	0.458	0.542	0.000
I42.4 Endocardial fibroelastosis	0.458	0.542	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.458	0.542	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.458	0.542	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.458	0.542	0.000
I24.1 Dressler's syndrome	0.457	0.543	0.000
W00-W19 Falls	0.457	0.543	0.000
I05.9 Mitral valve disease, unspecified	0.455	0.545	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.454	0.546	0.000
S62.6 Fracture of other finger	0.452	0.548	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.451	0.549	0.000
I08.0 Disorders of both mitral and aortic valves	0.450	0.550	0.000
I51.7 Cardiomegaly	0.449	0.551	0.000
I07.9 Tricuspid valve disease, unspecified	0.448	0.551	0.000
I07.8 Other tricuspid valve diseases	0.448	0.551	0.000
I07.2 Tricuspid stenosis with insufficiency	0.448	0.551	0.000
I07.0 Tricuspid stenosis	0.448	0.551	0.000
I11 Hypertensive heart disease	0.448	0.551	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.447	0.553	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.446	0.554	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.446	0.554	0.000
I45.8 Other specified conduction disorders	0.444	0.556	0.000
I45.5 Other specified heart block	0.444	0.556	0.000
I45.4 Nonspecific intraventricular block	0.444	0.556	0.000
I45.2 Bifascicular block	0.444	0.556	0.000
I45.0 Right fascicular block	0.444	0.556	0.000
C44.4 Skin of scalp and neck	0.443	0.557	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.442	0.558	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.442	0.558	0.000
I79.1 Aortitis in diseases classified elsewhere	0.442	0.558	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.442	0.558	0.000
I72.9 Aneurysm of unspecified site	0.441	0.559	0.000
I72.8 Aneurysm of other specified arteries	0.441	0.559	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.441	0.559	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.441	0.559	0.000
I72.3 Aneurysm of iliac artery	0.441	0.559	0.000
I72.2 Aneurysm of renal artery	0.441	0.559	0.000
I72.1 Aneurysm of artery of upper extremity	0.441	0.559	0.000
I72.0 Aneurysm of carotid artery	0.441	0.559	0.000
I72.4 Aneurysm of artery of lower extremity	0.440	0.560	0.000
S90-S99 Injuries to the ankle and foot	0.439	0.561	0.000
I45.6 Preexcitation syndrome	0.435	0.565	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.435	0.565	0.000
S60 Superficial injury of wrist and hand	0.435	0.565	0.000
I05.8 Other mitral valve diseases	0.433	0.567	0.000
I05.2 Mitral stenosis with insufficiency	0.433	0.567	0.000
I05.1 Rheumatic mitral insufficiency	0.433	0.567	0.000
I05.0 Mitral stenosis	0.433	0.567	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.430	0.570	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.427	0.573	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.426	0.574	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.424	0.576	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.424	0.576	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.424	0.576	0.000
I97.1 Other functional disturbances following cardiac surgery	0.424	0.576	0.000
I97.0 Postcardiotomy syndrome	0.424	0.576	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.424	0.576	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.424	0.576	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.424	0.576	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.424	0.576	0.000
I98.0 Cardiovascular syphilis	0.424	0.576	0.000
D00-D09 In situ neoplasms	0.423	0.577	0.000
I12 Hypertensive renal disease	0.423	0.577	0.000
C44.2 Skin of ear and external auricular canal	0.420	0.580	0.000
I31.3 Pericardial effusion (noninflammatory)	0.419	0.581	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.417	0.583	0.000
I06.8 Other rheumatic aortic valve diseases	0.417	0.583	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.417	0.583	0.000
I06.1 Rheumatic aortic insufficiency	0.417	0.583	0.000
I06.0 Rheumatic aortic stenosis	0.417	0.583	0.000
I09.9 Rheumatic heart disease, unspecified	0.417	0.583	0.000
I09.8 Other specified rheumatic heart diseases	0.417	0.583	0.000
I09.2 Chronic rheumatic pericarditis	0.417	0.583	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.417	0.583	0.000
I09.0 Rheumatic myocarditis	0.417	0.583	0.000
G90-G99 Other disorders of the nervous system	0.415	0.585	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.414	0.586	0.000
I73.0 Raynaud's syndrome	0.411	0.589	0.000
C43 Malignant melanoma of skin	0.409	0.591	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.408	0.592	0.000
C44.3 Skin of other and unspecified parts of face	0.407	0.593	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.406	0.593	0.000
I83 Varicose veins of lower extremities	0.406	0.594	0.000
L50-L54 Urticaria and erythema	0.406	0.594	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.403	0.597	0.000
I34.1 Mitral (valve) prolapse	0.402	0.597	0.000
S62.61 Fracture of other finger (open)	0.402	0.598	0.000
L90 Atrophic disorders of skin	0.401	0.599	0.000
S62.60 Fracture of other finger (closed)	0.401	0.599	0.000
W19 Unspecified fall	0.401	0.599	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.401	0.599	0.000
I15 Secondary hypertension	0.400	0.599	0.000
I13 Hypertensive heart and renal disease	0.400	0.599	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.400	0.600	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.400	0.600	0.000
S64 Injury of nerves at wrist and hand level	0.399	0.601	0.000
S10-S19 Injuries to the neck	0.397	0.603	0.000
S50-S59 Injuries to the elbow and forearm	0.397	0.603	0.000
C90.0 Multiple myeloma	0.396	0.604	0.000
I50.1 Left ventricular failure	0.395	0.604	0.000
I60-I69 Cerebrovascular diseases	0.395	0.605	0.000
I47.0 Reentry ventricular arrhythmia	0.394	0.605	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.394	0.605	0.000
S70-S79 Injuries to the hip and thigh	0.394	0.606	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.393	0.607	0.000
S80-S89 Injuries to the knee and lower leg	0.392	0.608	0.000
I78.9 Disease of capillaries, unspecified	0.391	0.609	0.000
I78.8 Other diseases of capillaries	0.391	0.609	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.391	0.609	0.000
C90.2 Plasmacytoma, extramedullary	0.390	0.610	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.390	0.610	0.000
S40-S49 Injuries to the shoulder and upper arm	0.387	0.612	0.000
T79-T79 Certain early complications of trauma	0.387	0.613	0.000
L40-L45 Papulosquamous disorders	0.387	0.613	0.000
T33-T35 Frostbite	0.386	0.614	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.386	0.614	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.386	0.614	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.386	0.614	0.000
T00-T07 Injuries involving multiple body regions	0.386	0.614	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.385	0.615	0.000
T66-T78 Other and unspecified effects of external causes	0.384	0.616	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.382	0.618	0.000
W20-W49 Exposure to inanimate mechanical forces	0.380	0.620	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.379	0.621	0.000
S69 Other and unspecified injuries of wrist and hand	0.378	0.622	0.000
S67 Crushing injury of wrist and hand	0.378	0.622	0.000
S65 Injury of blood vessels at wrist and hand level	0.378	0.622	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.378	0.622	0.000
S20-S29 Injuries to the thorax	0.378	0.622	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.377	0.622	0.000
Y40 Systemic antibiotics	0.377	0.623	0.000
Y52 Agents primarily affecting the cardiovascular system	0.376	0.624	0.000
G30-G32 Other degenerative diseases of the nervous system	0.375	0.625	0.000
W13 Fall from, out of or through building or structure	0.375	0.625	0.000
S32 Fracture of lumbar spine and pelvis	0.373	0.627	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.372	0.628	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.372	0.628	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.372	0.628	0.000
C44.0 Skin of lip	0.372	0.628	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.371	0.629	0.000
I74.8 Embolism and thrombosis of other arteries	0.371	0.629	0.000
I74.5 Embolism and thrombosis of iliac artery	0.371	0.629	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.371	0.629	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.371	0.629	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.371	0.629	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.371	0.629	0.000
W19.9 Unspecified place	0.371	0.629	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.370	0.630	0.000
Chapter V Mental and behavioural disorders	0.369	0.631	0.000
I12.9 Hypertensive renal disease without renal failure	0.369	0.631	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.369	0.631	0.000
I82.3 Embolism and thrombosis of renal vein	0.368	0.632	0.000
I82.2 Embolism and thrombosis of vena cava	0.368	0.632	0.000
I82.1 Thrombophlebitis migrans	0.368	0.632	0.000
I82.0 Budd-Chiari syndrome	0.368	0.632	0.000
S91 Open wound of ankle and foot	0.368	0.632	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.367	0.633	0.000
V10-V19 Pedal cyclist injured in transport accident	0.367	0.633	0.000
I42.0 Dilated cardiomyopathy	0.366	0.633	0.000
L90.5 Scar conditions and fibrosis of skin	0.367	0.633	0.000
C44.7 Skin of lower limb, including hip	0.367	0.633	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.366	0.634	0.000
I28 Other diseases of pulmonary vessels	0.365	0.634	0.000
C92 Myeloid leukaemia	0.364	0.635	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.364	0.636	0.000
L80 Vitiligo	0.364	0.636	0.000
Chapter XXII Codes for special purposes	0.364	0.636	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.364	0.636	0.000
S60.8 Other superficial injuries of wrist and hand	0.363	0.637	0.000
G70-G73 Diseases of myoneural junction and muscle	0.362	0.638	0.000
T51 Toxic effect of alcohol	0.361	0.639	0.000
L81 Other disorders of pigmentation	0.361	0.639	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.361	0.639	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.361	0.639	0.000
Y44 Agents primarily affecting blood constituents	0.359	0.641	0.000
X60-X84 Intentional self-harm	0.358	0.641	0.000
Y57 Other and unspecified drugs and medicaments	0.358	0.642	0.000
S68 Traumatic amputation of wrist and hand	0.358	0.642	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.357	0.642	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.357	0.642	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.357	0.642	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.357	0.642	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.357	0.642	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.357	0.642	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.357	0.642	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.357	0.642	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.356	0.644	0.000
Y35-Y36 Legal intervention and operations of war	0.356	0.644	0.000
Y10-Y34 Event of undetermined intent	0.356	0.644	0.000
Y00-Y09 Assault	0.356	0.644	0.000
X85-X99 Assault	0.356	0.644	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.356	0.644	0.000
X50-X57 Overexertion, travel and privation	0.356	0.644	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.356	0.644	0.000
X30-X39 Exposure to forces of nature	0.356	0.644	0.000
X20-X29 Contact with venomous animals and plants	0.356	0.644	0.000
X10-X19 Contact with heat and hot substances	0.356	0.644	0.000
X00-X09 Exposure to smoke, fire and flames	0.356	0.644	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.356	0.644	0.000
W75-W84 Other accidental threats to breathing	0.356	0.644	0.000
W65-W74 Accidental drowning and submersion	0.356	0.644	0.000
W50-W64 Exposure to animate mechanical forces	0.356	0.644	0.000
V98-V99 Other and unspecified transport accidents	0.356	0.644	0.000
V95-V97 Air and space transport accidents	0.356	0.644	0.000
V90-V94 Water transport accidents	0.356	0.644	0.000
V80-V89 Other land transport accidents	0.356	0.644	0.000
V70-V79 Bus occupant injured in transport accident	0.356	0.644	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.356	0.644	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.356	0.644	0.000
V40-V49 Car occupant injured in transport accident	0.356	0.644	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.356	0.644	0.000
V20-V29 Motorcycle rider injured in transport accident	0.356	0.644	0.000
V01-V09 Pedestrian injured in transport accident	0.356	0.644	0.000
I86.4 Gastric varices	0.355	0.644	0.000
I84.6 Residual haemorrhoidal skin tags	0.355	0.645	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.355	0.645	0.000
C81 Hodgkin's disease	0.355	0.645	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.355	0.645	0.000
C91 Lymphoid leukaemia	0.355	0.645	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.354	0.646	0.000
I01.8 Other acute rheumatic heart disease	0.354	0.646	0.000
I01.2 Acute rheumatic myocarditis	0.354	0.646	0.000
I01.1 Acute rheumatic endocarditis	0.354	0.646	0.000
I01.0 Acute rheumatic pericarditis	0.354	0.646	0.000
I02.9 Rheumatic chorea without heart involvement	0.354	0.646	0.000
I02.0 Rheumatic chorea with heart involvement	0.354	0.646	0.000
I21.9 Acute myocardial infarction, unspecified	0.354	0.646	0.000
I82.8 Embolism and thrombosis of other specified veins	0.353	0.647	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.353	0.647	0.000
I88.8 Other nonspecific lymphadenitis	0.353	0.647	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.353	0.647	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.353	0.647	0.000
I80 Phlebitis and thrombophlebitis	0.352	0.647	0.001
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.352	0.647	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.352	0.647	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.352	0.647	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.352	0.647	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.352	0.647	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.352	0.647	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.352	0.647	0.000
T90 Sequelae of injuries of head	0.352	0.648	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.350	0.650	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.349	0.650	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.349	0.650	0.000
I89.1 Lymphangitis	0.349	0.650	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.349	0.651	0.000
W06 Fall involving bed	0.348	0.652	0.000
L10-L14 Bullous disorders	0.348	0.652	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.348	0.652	0.000
C15-C26 Malignant neoplasms of digestive organs	0.348	0.652	0.000
L20-L30 Dermatitis and eczema	0.347	0.653	0.000
I89.0 Lymphoedema, not elsewhere classified	0.344	0.655	0.000
S61 Open wound of wrist and hand	0.344	0.656	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations