TreeWAS – Variant ID: rs146650065

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.997	0.003
Chapter II Neoplasms	0.994	0.006
M05-M14 Inflammatory polyarthropathies	0.992	0.008
M20-M25 Other joint disorders	0.987	0.013
M13 Other arthritis	0.985	0.015
M13.9 Arthritis, unspecified	0.981	0.019
R11 Nausea and vomiting	0.980	0.020
M13.99 Arthritis, unspecified (Site unspecified)	0.977	0.023
M23 Internal derangement of knee	0.976	0.024
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.974	0.026
N20-N23 Urolithiasis	0.967	0.033
M23.2 Derangement of meniscus due to old tear or injury	0.960	0.040
N80-N98 Noninflammatory disorders of female genital tract	0.957	0.043
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.957	0.043
Chapter X Diseases of the respiratory system	0.946	0.054
N84 Polyp of female genital tract	0.941	0.059
N23 Unspecified renal colic	0.937	0.063
N84.0 Polyp of corpus uteri	0.923	0.077
C43-C44 Melanoma and other malignant neoplasms of skin	0.919	0.081
R93 Abnormal findings on diagnostic imaging of other body structures	0.915	0.085
Chapter I Certain infectious and parasitic diseases	0.912	0.088
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.908	0.092
Chapter V Mental and behavioural disorders	0.906	0.094
J40-J47 Chronic lower respiratory diseases	0.901	0.099
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.899	0.101
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.894	0.106
N10-N16 Renal tubulo-interstitial diseases	0.892	0.108
R18 Ascites	0.887	0.113
Chapter IX Diseases of the circulatory system	0.883	0.117
R10 Abdominal and pelvic pain	0.883	0.117
N60-N64 Disorders of breast	0.879	0.121
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.875	0.125
I30-I52 Other forms of heart disease	0.867	0.133
M70-M79 Other soft tissue disorders	0.867	0.133
C44 Other malignant neoplasms of skin	0.864	0.136
S80-S89 Injuries to the knee and lower leg	0.860	0.140
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.859	0.141
R10.4 Other and unspecified abdominal pain	0.858	0.142
R94 Abnormal results of function studies	0.854	0.146
R17 Unspecified jaundice	0.846	0.154
N70-N77 Inflammatory diseases of female pelvic organs	0.846	0.154
M13.91 Arthritis, unspecified (Shoulder region)	0.843	0.157
N00-N08 Glomerular diseases	0.837	0.163
B95-B98 Bacterial, viral and other infectious agents	0.832	0.168
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.832	0.168
C34 Malignant neoplasm of bronchus and lung	0.830	0.170
C51-C58 Malignant neoplasms of female genital organs	0.829	0.171
N95 Menopausal and other perimenopausal disorders	0.829	0.171
N90 Other noninflammatory disorders of vulva and perineum	0.823	0.177
M50-M54 Other dorsopathies	0.816	0.184
R14 Flatulence and related conditions	0.814	0.186
D37-D48 Neoplasms of uncertain or unknown behaviour	0.811	0.189
J30-J39 Other diseases of upper respiratory tract	0.811	0.189
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.809	0.191
S00-S09 Injuries to the head	0.808	0.192
R42 Dizziness and giddiness	0.805	0.195
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.804	0.196
J44 Other chronic obstructive pulmonary disease	0.804	0.196
J43 Emphysema	0.801	0.199
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.798	0.201
C44.3 Skin of other and unspecified parts of face	0.797	0.203
M23.3 Other meniscus derangements	0.797	0.203
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.797	0.203
M10 Gout	0.796	0.204
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.793	0.207
N99-N99 Other disorders of the genitourinary system	0.793	0.207
Chapter XX External causes of morbidity and mortality	0.791	0.209
F40-F48 Neurotic, stress-related and somatoform disorders	0.790	0.210
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.790	0.210
Chapter VI Diseases of the nervous system	0.788	0.212
R91 Abnormal findings on diagnostic imaging of lung	0.785	0.215
M23.8 Other internal derangements of knee	0.783	0.217
Chapter VIII Diseases of the ear and mastoid process	0.780	0.219
N20 Calculus of kidney and ureter	0.780	0.220
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.780	0.220
N85 Other noninflammatory disorders of uterus, except cervix	0.779	0.221
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.771	0.228
N13 Obstructive and reflux uropathy	0.769	0.231
I60-I69 Cerebrovascular diseases	0.768	0.232
R94.5 Abnormal results of liver function studies	0.767	0.233
M25 Other joint disorders, not elsewhere classified	0.767	0.233
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.763	0.237
R19 Other symptoms and signs involving the digestive system and abdomen	0.761	0.239
N84.1 Polyp of cervix uteri	0.760	0.240
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.759	0.241
I44 Atrioventricular and left bundle-branch block	0.758	0.242
C44.1 Skin of eyelid, including canthus	0.757	0.243
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.757	0.243
T81 Complications of procedures, not elsewhere classified	0.756	0.244
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.756	0.244
M79 Other soft tissue disorders, not elsewhere classified	0.755	0.245
Chapter VII Diseases of the eye and adnexa	0.754	0.246
N95.0 Postmenopausal bleeding	0.753	0.247
D00-D09 In situ neoplasms	0.750	0.250
C34.9 Bronchus or lung, unspecified	0.750	0.250
M07 Psoriatic and enteropathic arthropathies	0.749	0.251
M80-M85 Disorders of bone density and structure	0.748	0.252
I47 Paroxysmal tachycardia	0.748	0.252
J45 Asthma	0.746	0.254
M24 Other specific joint derangements	0.741	0.259
B35-B49 Mycoses	0.741	0.259
J00-J06 Acute upper respiratory infections	0.741	0.259
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.741	0.259
I45 Other conduction disorders	0.740	0.260
N60 Benign mammary dysplasia	0.739	0.261
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.738	0.262
Chapter XXII Codes for special purposes	0.737	0.263
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.735	0.265
N30-N39 Other diseases of urinary system	0.731	0.269
J43.9 Emphysema, unspecified	0.729	0.271
I51 Complications and ill-defined descriptions of heart disease	0.728	0.272
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.728	0.272
N63 Unspecified lump in breast	0.723	0.277
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.722	0.278
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.721	0.279
J44.8 Other specified chronic obstructive pulmonary disease	0.721	0.279
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283
M91-M94 Chondropathies	0.717	0.283
M86-M90 Other osteopathies	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M40-M43 Deforming dorsopathies	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.716	0.284
C56 Malignant neoplasm of ovary	0.716	0.284
M20 Acquired deformities of fingers and toes	0.715	0.285
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.713	0.287
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.713	0.287
M14 Arthropathies in other diseases classified elsewhere	0.711	0.289
M12 Other specific arthropathies	0.711	0.289
M11 Other crystal arthropathies	0.711	0.289
M09 Juvenile arthritis in diseases classified elsewhere	0.711	0.289
M08 Juvenile arthritis	0.711	0.289
M05 Seropositive rheumatoid arthritis	0.711	0.289
N87 Dysplasia of cervix uteri	0.709	0.291
D10-D36 Benign neoplasms	0.709	0.291
Chapter XII Diseases of the skin and subcutaneous tissue	0.709	0.291
M13.97 Arthritis, unspecified (Ankle and foot)	0.708	0.291
S83.2 Tear of meniscus, current	0.708	0.292
Chapter IV Endocrine, nutritional and metabolic diseases	0.708	0.292
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.707	0.292
M34 Systemic sclerosis	0.707	0.292
M33 Dermatopolymyositis	0.707	0.292
M32 Systemic lupus erythematosus	0.707	0.292
M31 Other necrotising vasculopathies	0.707	0.292
M30 Polyarteritis nodosa and related conditions	0.707	0.292
M22 Disorders of patella	0.707	0.292
M21 Other acquired deformities of limbs	0.707	0.292
M13.8 Other specified arthritis	0.706	0.294
M13.1 Monoarthritis, not elsewhere classified	0.706	0.294
M13.0 Polyarthritis, unspecified	0.706	0.294
M54 Dorsalgia	0.706	0.294
N64 Other disorders of breast	0.704	0.296
M13.98 Arthritis, unspecified (Other)	0.703	0.297
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.703	0.297
M13.94 Arthritis, unspecified (Hand)	0.703	0.297
M13.93 Arthritis, unspecified (Forearm)	0.703	0.297
M13.92 Arthritis, unspecified (Upper arm)	0.703	0.297
I05-I09 Chronic rheumatic heart diseases	0.702	0.298
C44.2 Skin of ear and external auricular canal	0.701	0.299
M23.9 Internal derangement of knee, unspecified	0.700	0.300
M23.6 Other spontaneous disruption of ligament(s) of knee	0.700	0.300
M23.5 Chronic instability of knee	0.700	0.300
M23.4 Loose body in knee	0.700	0.300
M23.1 Discoid meniscus (congenital)	0.700	0.300
M23.0 Cystic meniscus	0.700	0.300
R90 Abnormal findings on diagnostic imaging of central nervous system	0.699	0.301
R92 Abnormal findings on diagnostic imaging of breast	0.699	0.301
N13.3 Other and unspecified hydronephrosis	0.698	0.302
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.697	0.303
J60-J70 Lung diseases due to external agents	0.697	0.303
S02 Fracture of skull and facial bones	0.697	0.303
T81.4 Infection following a procedure, not elsewhere classified	0.697	0.303
C50-C50 Malignant neoplasm of breast	0.697	0.303
N90.4 Leukoplakia of vulva	0.695	0.305
S60-S69 Injuries to the wrist and hand	0.694	0.306
N22 Calculus of urinary tract in diseases classified elsewhere	0.693	0.307
C79 Secondary malignant neoplasm of other sites	0.692	0.308
N72 Inflammatory disease of cervix uteri	0.689	0.311
J90-J94 Other diseases of pleura	0.688	0.311
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.688	0.312
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.688	0.312
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.688	0.312
I38 Endocarditis, valve unspecified	0.687	0.313
N98 Complications associated with artificial fertilisation	0.686	0.313
N91 Absent, scanty and rare menstruation	0.686	0.313
N82 Fistulae involving female genital tract	0.686	0.313
N96 Habitual aborter	0.686	0.313
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.686	0.314
T79-T79 Certain early complications of trauma	0.686	0.314
T66-T78 Other and unspecified effects of external causes	0.686	0.314
T33-T35 Frostbite	0.686	0.314
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.686	0.314
T26-T28 Burns and corrosions confined to eye and internal organs	0.686	0.314
T20-T25 Burns and corrosions of external body surface, specified by site	0.686	0.314
T15-T19 Effects of foreign body entering through natural orifice	0.686	0.314
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.686	0.314
T00-T07 Injuries involving multiple body regions	0.686	0.314
S90-S99 Injuries to the ankle and foot	0.686	0.314
S10-S19 Injuries to the neck	0.686	0.314
F41 Other anxiety disorders	0.685	0.315
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.684	0.316
N03 Chronic nephritic syndrome	0.684	0.316
R41 Other symptoms and signs involving cognitive functions and awareness	0.682	0.318
C64-C68 Malignant neoplasms of urinary tract	0.681	0.319
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.678	0.322
F30-F39 Mood [affective] disorders	0.677	0.323
G50-G59 Nerve, nerve root and plexus disorders	0.676	0.324
N25-N29 Other disorders of kidney and ureter	0.676	0.324
C71 Malignant neoplasm of brain	0.676	0.324
H53-H54 Visual disturbances and blindness	0.674	0.325
N84.9 Polyp of female genital tract, unspecified	0.674	0.326
N84.8 Polyp of other parts of female genital tract	0.674	0.326
N84.3 Polyp of vulva	0.674	0.326
N84.2 Polyp of vagina	0.674	0.326
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.673	0.327
N92 Excessive, frequent and irregular menstruation	0.672	0.328
N97 Female infertility	0.672	0.328
N88 Other noninflammatory disorders of cervix uteri	0.671	0.329
M72 Fibroblastic disorders	0.671	0.329
J95-J99 Other diseases of the respiratory system	0.670	0.330
T36-T50 Poisoning by drugs, medicaments and biological substances	0.669	0.330
N73 Other female pelvic inflammatory diseases	0.669	0.331
C15-C26 Malignant neoplasms of digestive organs	0.668	0.331
N40-N51 Diseases of male genital organs	0.667	0.333
S83.6 Sprain and strain of other and unspecified parts of knee	0.667	0.333
M65-M68 Disorders of synovium and tendon	0.666	0.333
I44.7 Left bundle-branch block, unspecified	0.666	0.334
I50 Heart failure	0.665	0.334
A00-A09 Intestinal infectious diseases	0.665	0.335
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.665	0.335
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.664	0.336
D25 Leiomyoma of uterus	0.664	0.336
J40 Bronchitis, not specified as acute or chronic	0.664	0.336
S20-S29 Injuries to the thorax	0.663	0.337
I46 Cardiac arrest	0.663	0.337
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.662	0.338
R47-R49 Symptoms and signs involving speech and voice	0.661	0.339
J80-J84 Other respiratory diseases principally affecting the interstitium	0.661	0.339
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.659	0.341
C43 Malignant melanoma of skin	0.659	0.341
C44.6 Skin of upper limb, including shoulder	0.658	0.342
M10.9 Gout, unspecified	0.656	0.344
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.656	0.344
R93.6 Abnormal findings on diagnostic imaging of limbs	0.656	0.344
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.656	0.344
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.656	0.344
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.656	0.344
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.656	0.344
S70-S79 Injuries to the hip and thigh	0.656	0.344
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.655	0.344
F17 Mental and behavioural disorders due to use of tobacco	0.655	0.345
N02 Recurrent and persistent haematuria	0.655	0.345
B97 Viral agents as the cause of diseases classified to other chapters	0.654	0.346
B99-B99 Other infectious diseases	0.654	0.346
B90-B94 Sequelae of infectious and parasitic diseases	0.654	0.346
B85-B89 Pediculosis, acariasis and other infestations	0.654	0.346
B65-B83 Helminthiases	0.654	0.346
B50-B64 Protozoal diseases	0.654	0.346
B20-B24 Human immunodeficiency virus [HIV] disease	0.654	0.346
B15-B19 Viral hepatitis	0.654	0.346
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.654	0.346
A80-A89 Viral infections of the central nervous system	0.654	0.346
A75-A79 Rickettsioses	0.654	0.346
A70-A74 Other diseases caused by chlamydiae	0.654	0.346
A65-A69 Other spirochaetal diseases	0.654	0.346
A50-A64 Infections with a predominantly sexual mode of transmission	0.654	0.346
A20-A28 Certain zoonotic bacterial diseases	0.654	0.346
A15-A19 Tuberculosis	0.654	0.346
C44.4 Skin of scalp and neck	0.654	0.346
R13 Dysphagia	0.654	0.346
C34.1 Upper lobe, bronchus or lung	0.653	0.346
N32 Other disorders of bladder	0.653	0.347
I47.2 Ventricular tachycardia	0.652	0.348
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.651	0.349
R15 Faecal incontinence	0.651	0.349
C80 Malignant neoplasm without specification of site	0.651	0.349
M79.6 Pain in limb	0.650	0.350
F99-F99 Unspecified mental disorder	0.650	0.350
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.650	0.350
F80-F89 Disorders of psychological development	0.650	0.350
F70-F79 Mental retardation	0.650	0.350
F60-F69 Disorders of adult personality and behaviour	0.650	0.350
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.650	0.350
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.650	0.350
F00-F09 Organic, including symptomatic, mental disorders	0.650	0.350
N17-N19 Renal failure	0.649	0.351
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.649	0.351
N21 Calculus of lower urinary tract	0.648	0.351
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.648	0.352
J33 Nasal polyp	0.648	0.352
N95.8 Other specified menopausal and perimenopausal disorders	0.648	0.352
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.648	0.352
N90.7 Vulvar cyst	0.647	0.353
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.646	0.354
J41 Simple and mucopurulent chronic bronchitis	0.646	0.354
J46 Status asthmaticus	0.646	0.354
J42 Unspecified chronic bronchitis	0.646	0.354
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.645	0.355
S01 Open wound of head	0.645	0.355
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.645	0.355
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.644	0.355
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.644	0.356
C38 Malignant neoplasm of heart, mediastinum and pleura	0.644	0.356
C32 Malignant neoplasm of larynx	0.644	0.356
C31 Malignant neoplasm of accessory sinuses	0.644	0.356
C30 Malignant neoplasm of nasal cavity and middle ear	0.644	0.356
C37 Malignant neoplasm of thymus	0.644	0.356
C33 Malignant neoplasm of trachea	0.644	0.356
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.643	0.357
R46 Symptoms and signs involving appearance and behaviour	0.641	0.359
R45 Symptoms and signs involving emotional state	0.641	0.359
R44 Other symptoms and signs involving general sensations and perceptions	0.641	0.359
R43 Disturbances of smell and taste	0.641	0.359
R40 Somnolence, stupor and coma	0.641	0.359
S40-S49 Injuries to the shoulder and upper arm	0.641	0.359
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.641	0.359
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.640	0.360
N15 Other renal tubulo-interstitial diseases	0.640	0.360
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.640	0.360
N11 Chronic tubulo-interstitial nephritis	0.640	0.360
N10 Acute tubulo-interstitial nephritis	0.640	0.360
N60.1 Diffuse cystic mastopathy	0.639	0.361
C34.3 Lower lobe, bronchus or lung	0.638	0.362
R20 Disturbances of skin sensation	0.638	0.362
M25.5 Pain in joint	0.637	0.363
I95-I99 Other and unspecified disorders of the circulatory system	0.637	0.363
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.637	0.363
I67 Other cerebrovascular diseases	0.635	0.365
J45.9 Asthma, unspecified	0.635	0.365
I00-I02 Acute rheumatic fever	0.633	0.367
R10.0 Acute abdomen	0.633	0.367
G90-G99 Other disorders of the nervous system	0.632	0.368
S50-S59 Injuries to the elbow and forearm	0.630	0.370
N80 Endometriosis	0.629	0.371
M35 Other systemic involvement of connective tissue	0.628	0.371
M50 Cervical disk disorders	0.628	0.372
D25.9 Leiomyoma of uterus, unspecified	0.628	0.372
M45-M49 Spondylopathies	0.627	0.373
M20.5 Other deformities of toe(s) (acquired)	0.627	0.373
N61 Inflammatory disorders of breast	0.626	0.374
B25-B34 Other viral diseases	0.625	0.375
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.625	0.375
C60-C63 Malignant neoplasms of male genital organs	0.625	0.375
N85.2 Hypertrophy of uterus	0.625	0.375
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.624	0.376
I45.6 Preexcitation syndrome	0.624	0.376
H65-H75 Diseases of middle ear and mastoid	0.624	0.376
M13.96 Arthritis, unspecified (Lower leg)	0.624	0.376
Chapter XXI Factors influencing health status and contact with health services	0.622	0.378
I52 Other heart disorders in diseases classified elsewhere	0.622	0.378
I48 Atrial fibrillation and flutter	0.622	0.378
I43 Cardiomyopathy in diseases classified elsewhere	0.622	0.378
I42 Cardiomyopathy	0.622	0.378
I41 Myocarditis in diseases classified elsewhere	0.622	0.378
I40 Acute myocarditis	0.622	0.378
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.622	0.378
I37 Pulmonary valve disorders	0.622	0.378
I36 Nonrheumatic tricuspid valve disorders	0.622	0.378
I33 Acute and subacute endocarditis	0.622	0.378
I32 Pericarditis in diseases classified elsewhere	0.622	0.378
I30 Acute pericarditis	0.622	0.378
M77 Other enthesopathies	0.621	0.378
M76 Enthesopathies of lower limb, excluding foot	0.621	0.378
M73 Soft tissue disorders in diseases classified elsewhere	0.621	0.378
M71 Other bursopathies	0.621	0.378
M70 Soft tissue disorders related to use, overuse and pressure	0.621	0.378
N75 Diseases of Bartholin's gland	0.620	0.380
C44.9 Malignant neoplasm of skin, unspecified	0.620	0.380
C44.8 Overlapping lesion of skin	0.620	0.380
C44.0 Skin of lip	0.620	0.380
B37 Candidiasis	0.619	0.381
J34 Other disorders of nose and nasal sinuses	0.619	0.381
G30-G32 Other degenerative diseases of the nervous system	0.617	0.382
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.617	0.383
T85 Complications of other internal prosthetic devices, implants and grafts	0.617	0.383
S89 Other and unspecified injuries of lower leg	0.616	0.383
S88 Traumatic amputation of lower leg	0.616	0.383
S87 Crushing injury of lower leg	0.616	0.383
S86 Injury of muscle and tendon at lower leg level	0.616	0.383
S85 Injury of blood vessels at lower leg level	0.616	0.383
S84 Injury of nerves at lower leg level	0.616	0.383
S81 Open wound of lower leg	0.616	0.383
S80 Superficial injury of lower leg	0.616	0.383
T88 Other complications of surgical and medical care, not elsewhere classified	0.616	0.384
T87 Complications peculiar to reattachment and amputation	0.616	0.384
T86 Failure and rejection of transplanted organs and tissues	0.616	0.384
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.616	0.384
T80 Complications following infusion, transfusion and therapeutic injection	0.616	0.384
D70-D77 Other diseases of blood and blood-forming organs	0.616	0.384
I49 Other cardiac arrhythmias	0.615	0.385
N20.0 Calculus of kidney	0.614	0.386
R94.3 Abnormal results of cardiovascular function studies	0.614	0.386
N85.0 Endometrial glandular hyperplasia	0.613	0.387
R94.8 Abnormal results of function studies of other organs and systems	0.612	0.388
R94.7 Abnormal results of other endocrine function studies	0.612	0.388
R94.6 Abnormal results of thyroid function studies	0.612	0.388
R94.4 Abnormal results of kidney function studies	0.612	0.388
R94.2 Abnormal results of pulmonary function studies	0.612	0.388
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.612	0.388
R94.0 Abnormal results of function studies of central nervous system	0.612	0.388
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.611	0.388
F40 Phobic anxiety disorders	0.611	0.388
I50.1 Left ventricular failure	0.611	0.389
M54.5 Low back pain	0.611	0.389
T81.3 Disruption of operation wound, not elsewhere classified	0.611	0.389
R79 Other abnormal findings of blood chemistry	0.608	0.392
I64 Stroke, not specified as haemorrhage or infarction	0.608	0.392
I44.2 Atrioventricular block, complete	0.607	0.392
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.607	0.393
N76 Other inflammation of vagina and vulva	0.607	0.393
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.607	0.393
N71 Inflammatory disease of uterus, except cervix	0.607	0.393
N70 Salpingitis and oophoritis	0.607	0.393
Z70-Z76 Persons encountering health services in other circumstances	0.607	0.393
M75 Shoulder lesions	0.607	0.393
S82 Fracture of lower leg, including ankle	0.606	0.393
R10.3 Pain localised to other parts of lower abdomen	0.605	0.395
N81 Female genital prolapse	0.603	0.397
N20.1 Calculus of ureter	0.603	0.397
M79.8 Other specified soft tissue disorders	0.602	0.398
I69 Sequelae of cerebrovascular disease	0.602	0.398
D45 Polycythaemia vera	0.601	0.398
C83 Diffuse non-Hodgkin's lymphoma	0.600	0.400
M06 Other rheumatoid arthritis	0.600	0.400
N08 Glomerular disorders in diseases classified elsewhere	0.600	0.400
N07 Hereditary nephropathy, not elsewhere classified	0.600	0.400
N06 Isolated proteinuria with specified morphological lesion	0.600	0.400
N05 Unspecified nephritic syndrome	0.600	0.400
N04 Nephrotic syndrome	0.600	0.400
N01 Rapidly progressive nephritic syndrome	0.600	0.400
N00 Acute nephritic syndrome	0.600	0.400
M13.90 Arthritis, unspecified (Multiple sites)	0.599	0.401
N93 Other abnormal uterine and vaginal bleeding	0.598	0.402
L40-L45 Papulosquamous disorders	0.598	0.402
I35 Nonrheumatic aortic valve disorders	0.597	0.403
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.597	0.403
C76 Malignant neoplasm of other and ill-defined sites	0.596	0.403
J36 Peritonsillar abscess	0.596	0.404
H53 Visual disturbances	0.596	0.404
C34.8 Overlapping lesion of bronchus and lung	0.595	0.405
C34.2 Middle lobe, bronchus or lung	0.595	0.405
C34.0 Main bronchus	0.595	0.405
D60-D64 Aplastic and other anaemias	0.595	0.405
Y60-Y69 Misadventures to patients during surgical and medical care	0.594	0.405
C57 Malignant neoplasm of other and unspecified female genital organs	0.594	0.406
C53 Malignant neoplasm of cervix uteri	0.594	0.406
C51 Malignant neoplasm of vulva	0.594	0.406
C58 Malignant neoplasm of placenta	0.594	0.406
C55 Malignant neoplasm of uterus, part unspecified	0.594	0.406
C52 Malignant neoplasm of vagina	0.594	0.406
N95.9 Menopausal and perimenopausal disorder, unspecified	0.594	0.406
N95.3 States associated with artificial menopause	0.594	0.406
N95.1 Menopausal and female climacteric states	0.594	0.406
I34 Nonrheumatic mitral valve disorders	0.594	0.406
N89 Other noninflammatory disorders of vagina	0.593	0.407
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.593	0.407
N32.8 Other specified disorders of bladder	0.592	0.408
F41.2 Mixed anxiety and depressive disorder	0.591	0.409
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.591	0.409
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.590	0.410
N90.6 Hypertrophy of vulva	0.590	0.410
N90.5 Atrophy of vulva	0.590	0.410
N90.3 Dysplasia of vulva, unspecified	0.590	0.410
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.590	0.410
N90.1 Moderate vulvar dysplasia	0.590	0.410
N90.0 Mild vulvar dysplasia	0.590	0.410
J09-J18 Influenza and pneumonia	0.589	0.411
I51.8 Other ill-defined heart diseases	0.589	0.411
R16.1 Splenomegaly, not elsewhere classified	0.588	0.412
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.588	0.412
J00 Acute nasopharyngitis [common cold]	0.587	0.412
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.586	0.414
M53 Other dorsopathies, not elsewhere classified	0.585	0.414
C54 Malignant neoplasm of corpus uteri	0.583	0.416
M54.56 Low back pain (Lumbar region)	0.583	0.417
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.582	0.418
D46 Myelodysplastic syndromes	0.582	0.418
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.582	0.418
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.582	0.418
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.582	0.418
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.582	0.418
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.582	0.418
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.582	0.418
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.582	0.418
J37 Chronic laryngitis and laryngotracheitis	0.581	0.418
J35 Chronic diseases of tonsils and adenoids	0.581	0.418
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.581	0.418
M20.2 Hallux rigidus	0.581	0.419
I51.9 Heart disease, unspecified	0.581	0.419

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations