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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs147138724
log Bayes Factor = 15.3443
Chromosome 19   position 32,582,254  (GRCh37) Explore rs147138724 on Ensembl!
Variant rs147138724 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
E11.9 Without complications
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.992 0.008 0.000
J40-J47 Chronic lower respiratory diseases
0.991 0.009 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.990 0.010 0.000
J44 Other chronic obstructive pulmonary disease
0.983 0.017 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.982 0.018 0.000
Z96 Presence of other functional implants
0.978 0.022 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
I25 Chronic ischaemic heart disease
0.975 0.025 0.000
M15-M19 Arthrosis
0.967 0.033 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.967 0.033 0.000
E10 Insulin-dependent diabetes mellitus
0.963 0.037 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.954 0.046 0.000
M45-M49 Spondylopathies
0.953 0.047 0.000
E70-E90 Metabolic disorders
0.952 0.048 0.000
M20-M25 Other joint disorders
0.951 0.048 0.000
Z86 Personal history of certain other diseases
0.949 0.051 0.000
I25.1 Atherosclerotic heart disease
0.948 0.052 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.942 0.058 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.941 0.059 0.000
K83 Other diseases of biliary tract
0.937 0.063 0.000
Z90.7 Acquired absence of genital organ(s)
0.934 0.066 0.000
Z96.1 Presence of intraocular lens
0.932 0.068 0.000
K50-K52 Noninfective enteritis and colitis
0.928 0.072 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.925 0.075 0.000
Chapter VII Diseases of the eye and adnexa
0.921 0.079 0.000
M05-M14 Inflammatory polyarthropathies
0.920 0.080 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.919 0.081 0.000
Z90.5 Acquired absence of kidney
0.919 0.081 0.000
Chapter I Certain infectious and parasitic diseases
0.919 0.081 0.000
I10-I15 Hypertensive diseases
0.916 0.084 0.000
K81 Cholecystitis
0.916 0.084 0.000
J09-J18 Influenza and pneumonia
0.914 0.086 0.000
E11.4 With neurological complications
0.913 0.087 0.000
M23 Internal derangement of knee
0.913 0.087 0.000
E10.9 Without complications
0.910 0.090 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.906 0.094 0.000
E78.0 Pure hypercholesterolaemia
0.905 0.095 0.000
Z96.6 Presence of orthopaedic joint implants
0.904 0.096 0.000
M17 Gonarthrosis [arthrosis of knee]
0.904 0.096 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.904 0.096 0.000
E14 Unspecified diabetes mellitus
0.902 0.098 0.000
J42 Unspecified chronic bronchitis
0.900 0.100 0.000
K35-K38 Diseases of appendix
0.897 0.103 0.000
E78.5 Hyperlipidaemia, unspecified
0.893 0.107 0.000
I60-I69 Cerebrovascular diseases
0.889 0.111 0.000
H25-H28 Disorders of lens
0.888 0.112 0.000
I12 Hypertensive renal disease
0.886 0.114 0.000
I30-I52 Other forms of heart disease
0.884 0.116 0.000
M23.3 Other meniscus derangements
0.880 0.120 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.878 0.122 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.878 0.122 0.000
H25 Senile cataract
0.874 0.126 0.000
K51 Ulcerative colitis
0.872 0.128 0.000
K80 Cholelithiasis
0.871 0.129 0.000
Z86.0 Personal history of other neoplasms
0.868 0.132 0.000
Chapter XIV Diseases of the genitourinary system
0.867 0.133 0.000
M40-M43 Deforming dorsopathies
0.865 0.135 0.000
I12.0 Hypertensive renal disease with renal failure
0.865 0.135 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.864 0.136 0.000
I21 Acute myocardial infarction
0.864 0.136 0.000
Z86.4 Personal history of psychoactive substance abuse
0.864 0.136 0.000
M70-M79 Other soft tissue disorders
0.864 0.136 0.000
M17.9 Gonarthrosis, unspecified
0.863 0.137 0.000
E11.3 With ophthalmic complications
0.863 0.137 0.000
M48 Other spondylopathies
0.860 0.140 0.000
E65-E68 Obesity and other hyperalimentation
0.859 0.141 0.000
K83.8 Other specified diseases of biliary tract
0.858 0.142 0.000
J18 Pneumonia, organism unspecified
0.858 0.142 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.855 0.145 0.000
A30-A49 Other bacterial diseases
0.854 0.146 0.000
K82 Other diseases of gallbladder
0.851 0.149 0.000
H25.8 Other senile cataract
0.846 0.154 0.000
K81.9 Cholecystitis, unspecified
0.835 0.165 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.833 0.167 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.827 0.173 0.000
Z96.0 Presence of urogenital implants
0.826 0.174 0.000
K35 Acute appendicitis
0.826 0.174 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.824 0.176 0.000
Z96.7 Presence of other bone and tendon implants
0.822 0.178 0.000
E11.1 With ketoacidosis
0.820 0.180 0.000
J90-J94 Other diseases of pleura
0.817 0.183 0.000
K65-K67 Diseases of peritoneum
0.816 0.184 0.000
Chapter XX External causes of morbidity and mortality
0.815 0.185 0.000
M19 Other arthrosis
0.814 0.186 0.000
M25 Other joint disorders, not elsewhere classified
0.810 0.190 0.000
M47 Spondylosis
0.809 0.191 0.000
G35 Multiple sclerosis
0.808 0.192 0.000
N20-N23 Urolithiasis
0.807 0.193 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
Z86.7 Personal history of diseases of the circulatory system
0.806 0.194 0.000
M16 Coxarthrosis [arthrosis of hip]
0.806 0.194 0.000
Z95.1 Presence of aortocoronary bypass graft
0.805 0.195 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.801 0.199 0.000
I74 Arterial embolism and thrombosis
0.800 0.200 0.000
E11.2 With renal complications
0.800 0.200 0.000
M48.0 Spinal stenosis
0.793 0.207 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.793 0.207 0.000
M13 Other arthritis
0.792 0.208 0.000
M24 Other specific joint derangements
0.792 0.208 0.000
L50-L54 Urticaria and erythema
0.791 0.209 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.789 0.211 0.000
M65-M68 Disorders of synovium and tendon
0.788 0.212 0.000
K51.9 Ulcerative colitis, unspecified
0.786 0.214 0.000
I69 Sequelae of cerebrovascular disease
0.784 0.216 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.782 0.218 0.000
M23.8 Other internal derangements of knee
0.782 0.218 0.000
M43 Other deforming dorsopathies
0.782 0.218 0.000
H53-H54 Visual disturbances and blindness
0.780 0.220 0.000
H25.9 Senile cataract, unspecified
0.780 0.220 0.000
E14.9 Without complications
0.778 0.222 0.000
J30-J39 Other diseases of upper respiratory tract
0.778 0.222 0.000
E11.5 With peripheral circulatory complications
0.776 0.224 0.000
Z92 Personal history of medical treatment
0.775 0.225 0.000
A41 Other septicaemia
0.775 0.225 0.000
G30-G32 Other degenerative diseases of the nervous system
0.775 0.225 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.775 0.225 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.775 0.225 0.000
M91-M94 Chondropathies
0.774 0.225 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.774 0.226 0.000
J40 Bronchitis, not specified as acute or chronic
0.773 0.227 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.773 0.227 0.000
N20 Calculus of kidney and ureter
0.772 0.228 0.000
Z90.2 Acquired absence of lung [part of]
0.771 0.229 0.000
M46 Other inflammatory spondylopathies
0.770 0.230 0.000
E10.5 With peripheral circulatory complications
0.769 0.231 0.000
M07 Psoriatic and enteropathic arthropathies
0.769 0.231 0.000
I24 Other acute ischaemic heart diseases
0.767 0.233 0.000
G70-G73 Diseases of myoneural junction and muscle
0.767 0.233 0.000
I42 Cardiomyopathy
0.767 0.233 0.000
I20 Angina pectoris
0.765 0.235 0.000
K50 Crohn's disease [regional enteritis]
0.765 0.235 0.000
B95-B98 Bacterial, viral and other infectious agents
0.763 0.237 0.000
K83.0 Cholangitis
0.762 0.238 0.000
K35.9 Acute appendicitis, unspecified
0.762 0.238 0.000
E20-E35 Disorders of other endocrine glands
0.760 0.240 0.000
G90-G99 Other disorders of the nervous system
0.760 0.240 0.000
E66 Obesity
0.758 0.242 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.758 0.242 0.000
E14.3 With ophthalmic complications
0.758 0.242 0.000
E86 Volume depletion
0.758 0.242 0.000
I73 Other peripheral vascular diseases
0.758 0.242 0.000
N40-N51 Diseases of male genital organs
0.758 0.242 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.757 0.243 0.000
S20-S29 Injuries to the thorax
0.756 0.244 0.000
J95-J99 Other diseases of the respiratory system
0.755 0.245 0.000
T66-T78 Other and unspecified effects of external causes
0.754 0.246 0.000
Chapter VIII Diseases of the ear and mastoid process
0.754 0.246 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.754 0.246 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.753 0.247 0.000
M80-M85 Disorders of bone density and structure
0.752 0.248 0.000
E50-E64 Other nutritional deficiencies
0.752 0.248 0.000
E10.4 With neurological complications
0.751 0.249 0.000
S00-S09 Injuries to the head
0.751 0.249 0.000
B35-B49 Mycoses
0.750 0.250 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.749 0.251 0.000
N20.0 Calculus of kidney
0.749 0.251 0.000
L20-L30 Dermatitis and eczema
0.748 0.252 0.000
L40-L45 Papulosquamous disorders
0.748 0.252 0.000
M17.0 Primary gonarthrosis, bilateral
0.748 0.252 0.000
Z96.8 Presence of other specified functional implants
0.748 0.252 0.000
G63.2 Diabetic polyneuropathy
0.746 0.254 0.000
K90-K93 Other diseases of the digestive system
0.745 0.255 0.000
I25.5 Ischaemic cardiomyopathy
0.745 0.255 0.000
S70-S79 Injuries to the hip and thigh
0.742 0.258 0.000
J18.1 Lobar pneumonia, unspecified
0.742 0.258 0.000
K83.1 Obstruction of bile duct
0.741 0.259 0.000
M48.06 Spinal stenosis (Lumbar region)
0.740 0.260 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
M47.9 Spondylosis, unspecified
0.738 0.262 0.000
I46 Cardiac arrest
0.738 0.262 0.000
I50 Heart failure
0.737 0.263 0.000
I34 Nonrheumatic mitral valve disorders
0.736 0.264 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.735 0.265 0.000
Z90.8 Acquired absence of other organs
0.735 0.265 0.000
K86 Other diseases of pancreas
0.733 0.267 0.000
I62 Other nontraumatic intracranial haemorrhage
0.733 0.267 0.000
J45 Asthma
0.732 0.268 0.000
M22 Disorders of patella
0.729 0.270 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.729 0.271 0.000
I20.0 Unstable angina
0.728 0.272 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.728 0.272 0.000
Z89 Acquired absence of limb
0.727 0.273 0.000
M25.5 Pain in joint
0.726 0.274 0.000
M86-M90 Other osteopathies
0.726 0.274 0.000
H43-H45 Disorders of vitreous body and globe
0.723 0.277 0.000
Z83 Family history of other specific disorders
0.723 0.277 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.723 0.277 0.000
M19.9 Arthrosis, unspecified
0.722 0.278 0.000
M43.1 Spondylolisthesis
0.722 0.278 0.000
J18.9 Pneumonia, unspecified
0.721 0.279 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
Z87 Personal history of other diseases and conditions
0.718 0.282 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.716 0.284 0.000
K81.0 Acute cholecystitis
0.716 0.284 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.716 0.284 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.716 0.284 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.715 0.285 0.000
K82.9 Disease of gallbladder, unspecified
0.714 0.286 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.713 0.287 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
Z97 Presence of other devices
0.713 0.287 0.000
M77 Other enthesopathies
0.712 0.288 0.000
I23 Certain current complications following acute myocardial infarction
0.711 0.289 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
I22 Subsequent myocardial infarction
0.711 0.289 0.000
E10.3 With ophthalmic complications
0.711 0.289 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.289 0.000
J46 Status asthmaticus
0.710 0.289 0.000
A49 Bacterial infection of unspecified site
0.710 0.290 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.710 0.290 0.000
J32 Chronic sinusitis
0.709 0.291 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.709 0.291 0.000
J18.0 Bronchopneumonia, unspecified
0.709 0.291 0.000
K80.4 Calculus of bile duct with cholecystitis
0.707 0.293 0.000
S50-S59 Injuries to the elbow and forearm
0.707 0.293 0.000
M75 Shoulder lesions
0.707 0.293 0.000
N25-N29 Other disorders of kidney and ureter
0.705 0.294 0.000
M10 Gout
0.705 0.295 0.000
M16.9 Coxarthrosis, unspecified
0.705 0.295 0.000
Z84 Family history of other conditions
0.705 0.295 0.000
Z81 Family history of mental and behavioural disorders
0.705 0.295 0.000
I72 Other aneurysm
0.703 0.297 0.000
Z90.3 Acquired absence of part of stomach
0.703 0.297 0.000
S10-S19 Injuries to the neck
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
Z96.9 Presence of functional implant, unspecified
0.701 0.298 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.701 0.298 0.000
Z96.4 Presence of endocrine implants
0.701 0.298 0.000
Z96.3 Presence of artificial larynx
0.701 0.298 0.000
Z96.2 Presence of otological and audiological implants
0.701 0.298 0.000
M13.9 Arthritis, unspecified
0.701 0.299 0.000
M21 Other acquired deformities of limbs
0.700 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.700 0.300 0.000
I25.6 Silent myocardial ischaemia
0.699 0.301 0.000
I25.4 Coronary artery aneurysm
0.699 0.301 0.000
I25.3 Aneurysm of heart
0.699 0.301 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.699 0.301 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.698 0.302 0.000
I11 Hypertensive heart disease
0.694 0.305 0.000
K04 Diseases of pulp and periapical tissues
0.694 0.306 0.000
M15 Polyarthrosis
0.693 0.306 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.693 0.307 0.000
Z90.0 Acquired absence of part of head and neck
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.693 0.307 0.000
E00-E07 Disorders of thyroid gland
0.693 0.307 0.000
J92 Pleural plaque
0.693 0.307 0.000
K81.1 Chronic cholecystitis
0.692 0.308 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.692 0.308 0.000
E10.1 With ketoacidosis
0.691 0.309 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.691 0.309 0.000
E10.8 With unspecified complications
0.690 0.310 0.000
E10.7 With multiple complications
0.690 0.310 0.000
E10.6 With other specified complications
0.690 0.310 0.000
E10.2 With renal complications
0.690 0.310 0.000
E10.0 With coma
0.690 0.310 0.000
H25.0 Senile incipient cataract
0.689 0.311 0.000
G40-G47 Episodic and paroxysmal disorders
0.689 0.311 0.000
Z95.2 Presence of prosthetic heart valve
0.687 0.313 0.000
M11 Other crystal arthropathies
0.687 0.313 0.000
N41 Inflammatory diseases of prostate
0.686 0.313 0.000
I21.9 Acute myocardial infarction, unspecified
0.686 0.313 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.685 0.315 0.000
K70-K77 Diseases of liver
0.685 0.315 0.000
K85 Acute pancreatitis
0.685 0.315 0.000
K11 Diseases of salivary glands
0.684 0.315 0.000
Z94 Transplanted organ and tissue status
0.683 0.316 0.000
M49 Spondylopathies in diseases classified elsewhere
0.683 0.317 0.000
M45 Ankylosing spondylitis
0.683 0.317 0.000
T79-T79 Certain early complications of trauma
0.683 0.317 0.000
E88 Other metabolic disorders
0.682 0.317 0.000
E85 Amyloidosis
0.682 0.317 0.000
E84 Cystic fibrosis
0.682 0.317 0.000
E79 Disorders of purine and pyrimidine metabolism
0.682 0.317 0.000
E77 Disorders of glycoprotein metabolism
0.682 0.317 0.000
E76 Disorders of glycosaminoglycan metabolism
0.682 0.317 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.682 0.317 0.000
E74 Other disorders of carbohydrate metabolism
0.682 0.317 0.000
E73 Lactose intolerance
0.682 0.317 0.000
E72 Other disorders of amino-acid metabolism
0.682 0.317 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.682 0.317 0.000
E70 Disorders of aromatic amino-acid metabolism
0.682 0.317 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.682 0.317 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.682 0.318 0.000
M34 Systemic sclerosis
0.682 0.318 0.000
M33 Dermatopolymyositis
0.682 0.318 0.000
M32 Systemic lupus erythematosus
0.682 0.318 0.000
M30 Polyarteritis nodosa and related conditions
0.682 0.318 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.682 0.318 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.679 0.321 0.000
I73.9 Peripheral vascular disease, unspecified
0.679 0.321 0.000
I30 Acute pericarditis
0.679 0.321 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.678 0.322 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.677 0.322 0.000
N40 Hyperplasia of prostate
0.677 0.323 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.676 0.324 0.000
E78.8 Other disorders of lipoprotein metabolism
0.676 0.324 0.000
E78.6 Lipoprotein deficiency
0.676 0.324 0.000
E78.4 Other hyperlipidaemia
0.676 0.324 0.000
E78.3 Hyperchylomicronaemia
0.676 0.324 0.000
E78.2 Mixed hyperlipidaemia
0.676 0.324 0.000
E78.1 Pure hyperglyceridaemia
0.676 0.324 0.000
T33-T35 Frostbite
0.674 0.325 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.674 0.325 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.674 0.325 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.674 0.325 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.674 0.325 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.674 0.325 0.000
T00-T07 Injuries involving multiple body regions
0.674 0.325 0.000
M31 Other necrotising vasculopathies
0.674 0.326 0.000
I63 Cerebral infarction
0.673 0.327 0.000
K07 Dentofacial anomalies [including malocclusion]
0.673 0.327 0.000
N10-N16 Renal tubulo-interstitial diseases
0.673 0.327 0.000
K83.9 Disease of biliary tract, unspecified
0.672 0.328 0.000
K83.5 Biliary cyst
0.672 0.328 0.000
K83.4 Spasm of sphincter of Oddi
0.672 0.328 0.000
K83.3 Fistula of bile duct
0.672 0.328 0.000
K83.2 Perforation of bile duct
0.672 0.328 0.000
A41.9 Septicaemia, unspecified
0.672 0.328 0.000
K66 Other disorders of peritoneum
0.672 0.328 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.671 0.329 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.670 0.330 0.000
L53 Other erythematous conditions
0.669 0.331 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.668 0.332 0.000
I31 Other diseases of pericardium
0.667 0.333 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
I42.0 Dilated cardiomyopathy
0.667 0.333 0.000
K14 Diseases of tongue
0.667 0.333 0.000
I33 Acute and subacute endocarditis
0.666 0.334 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.666 0.334 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.665 0.335 0.000
M23.4 Loose body in knee
0.665 0.335 0.000
N76 Other inflammation of vagina and vulva
0.664 0.336 0.000
L10-L14 Bullous disorders
0.664 0.336 0.000
Z87.0 Personal history of diseases of the respiratory system
0.663 0.337 0.000
G61 Inflammatory polyneuropathy
0.661 0.339 0.000
M07.3 Other psoriatic arthropathies
0.661 0.339 0.000
I77 Other disorders of arteries and arterioles
0.660 0.339 0.000
H55-H59 Other disorders of eye and adnexa
0.660 0.339 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.660 0.339 0.000
H10-H13 Disorders of conjunctiva
0.660 0.339 0.000
S01 Open wound of head
0.660 0.340 0.000
M14 Arthropathies in other diseases classified elsewhere
0.659 0.340 0.000
M12 Other specific arthropathies
0.659 0.340 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.659 0.340 0.000
M08 Juvenile arthritis
0.659 0.340 0.000
Z95.3 Presence of xenogenic heart valve
0.659 0.341 0.000
M18 Arthrosis of first carpometacarpal joint
0.659 0.341 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.659 0.341 0.000
B99-B99 Other infectious diseases
0.659 0.341 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.659 0.341 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.659 0.341 0.000
B65-B83 Helminthiases
0.659 0.341 0.000
B50-B64 Protozoal diseases
0.659 0.341 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
B15-B19 Viral hepatitis
0.659 0.341 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.659 0.341 0.000
A80-A89 Viral infections of the central nervous system
0.659 0.341 0.000
A75-A79 Rickettsioses
0.659 0.341 0.000
A70-A74 Other diseases caused by chlamydiae
0.659 0.341 0.000
A65-A69 Other spirochaetal diseases
0.659 0.341 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.341 0.000
A20-A28 Certain zoonotic bacterial diseases
0.659 0.341 0.000
A15-A19 Tuberculosis
0.659 0.341 0.000
K80.8 Other cholelithiasis
0.659 0.341 0.000
J35 Chronic diseases of tonsils and adenoids
0.658 0.342 0.000
I15 Secondary hypertension
0.657 0.343 0.000
I13 Hypertensive heart and renal disease
0.657 0.343 0.000
I49 Other cardiac arrhythmias
0.657 0.343 0.000
K81.8 Other cholecystitis
0.656 0.343 0.000
J17 Pneumonia in diseases classified elsewhere
0.655 0.344 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.655 0.344 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.655 0.344 0.000
J12 Viral pneumonia, not elsewhere classified
0.655 0.344 0.000
J11 Influenza, virus not identified
0.655 0.344 0.000
J10 Influenza due to identified influenza virus
0.655 0.344 0.000
J14 Pneumonia due to Haemophilus influenzae
0.655 0.344 0.000
J09 Influenza due to certain identified influenza virus
0.655 0.344 0.000
M06 Other rheumatoid arthritis
0.655 0.345 0.000
I50.1 Left ventricular failure
0.655 0.345 0.000
M23.9 Internal derangement of knee, unspecified
0.655 0.345 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.655 0.345 0.000
M23.5 Chronic instability of knee
0.655 0.345 0.000
M23.1 Discoid meniscus (congenital)
0.655 0.345 0.000
M23.0 Cystic meniscus
0.655 0.345 0.000
I70 Atherosclerosis
0.653 0.347 0.000
M35 Other systemic involvement of connective tissue
0.653 0.347 0.000
J60-J70 Lung diseases due to external agents
0.652 0.347 0.000
K51.8 Other ulcerative colitis
0.652 0.348 0.000
N50 Other disorders of male genital organs
0.652 0.348 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.650 0.350 0.000
M05 Seropositive rheumatoid arthritis
0.650 0.350 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.650 0.350 0.000
M65 Synovitis and tenosynovitis
0.648 0.352 0.000
M17.5 Other secondary gonarthrosis
0.648 0.352 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.648 0.352 0.000
M17.3 Other posttraumatic gonarthrosis
0.648 0.352 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.648 0.352 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.648 0.352 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.647 0.353 0.000
E14.8 With unspecified complications
0.647 0.353 0.000
E14.7 With multiple complications
0.647 0.353 0.000
E14.6 With other specified complications
0.647 0.353 0.000
E14.5 With peripheral circulatory complications
0.647 0.353 0.000
E14.4 With neurological complications
0.647 0.353 0.000
E14.2 Withrenal complications
0.647 0.353 0.000
E14.1 With ketoacidosis
0.647 0.353 0.000
E14.0 With coma
0.647 0.353 0.000
H53 Visual disturbances
0.647 0.353 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.646 0.354 0.000
K37 Unspecified appendicitis
0.645 0.355 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.645 0.355 0.000
K82.4 Cholesterolosis of gallbladder
0.645 0.355 0.000
H50 Other strabismus
0.644 0.355 0.000
N00-N08 Glomerular diseases
0.644 0.356 0.000
K82.8 Other specified diseases of gallbladder
0.644 0.356 0.000
N70 Salpingitis and oophoritis
0.643 0.357 0.000
K38 Other diseases of appendix
0.643 0.357 0.000
K36 Other appendicitis
0.643 0.357 0.000
J32.0 Chronic maxillary sinusitis
0.642 0.358 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.641 0.359 0.000
M24.1 Other articular cartilage disorders
0.641 0.359 0.000
J33 Nasal polyp
0.640 0.360 0.000
I12.9 Hypertensive renal disease without renal failure
0.639 0.360 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.639 0.360 0.000
K50.0 Crohn's disease of small intestine
0.639 0.361 0.000
K02 Dental caries
0.639 0.361 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.639 0.361 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.638 0.362 0.000
I46.9 Cardiac arrest, unspecified
0.638 0.362 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.637 0.362 0.000
M48.09 Spinal stenosis (Site unspecified)
0.637 0.362 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.637 0.363 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.637 0.363 0.000
S42 Fracture of shoulder and upper arm
0.637 0.363 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.637 0.363 0.000
H27 Other disorders of lens
0.637 0.363 0.000
E66.8 Other obesity
0.635 0.365 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.635 0.365 0.000
M25.50 Pain in joint (Multiple sites)
0.635 0.365 0.000
K35.3 Acute appendicitis with localized peritonitis
0.634 0.366 0.000
I52 Other heart disorders in diseases classified elsewhere
0.634 0.366 0.000
I48 Atrial fibrillation and flutter
0.634 0.366 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.634 0.366 0.000
I41 Myocarditis in diseases classified elsewhere
0.634 0.366 0.000
I40 Acute myocarditis
0.634 0.366 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.634 0.366 0.000
I36 Nonrheumatic tricuspid valve disorders
0.634 0.366 0.000
I32 Pericarditis in diseases classified elsewhere
0.634 0.366 0.000
K09 Cysts of oral region, not elsewhere classified
0.633 0.367 0.000
E66.9 Obesity, unspecified
0.633 0.367 0.000
I61 Intracerebral haemorrhage
0.631 0.369 0.000
M23.37 Other meniscus derangements-Capsular lig
0.631 0.369 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.631 0.369 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.631 0.369 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.631 0.369 0.000
S40 Superficial injury of shoulder and upper arm
0.630 0.370 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.630 0.370 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.630 0.370 0.000
G37 Other demyelinating diseases of central nervous system
0.630 0.370 0.000
G36 Other acute disseminated demyelination
0.630 0.370 0.000
I05-I09 Chronic rheumatic heart diseases
0.629 0.370 0.000
G60 Hereditary and idiopathic neuropathy
0.629 0.371 0.000
G64 Other disorders of peripheral nervous system
0.629 0.371 0.000
N99-N99 Other disorders of the genitourinary system
0.629 0.371 0.000
K10 Other diseases of jaws
0.628 0.372 0.000
I67 Other cerebrovascular diseases
0.627 0.372 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.627 0.373 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.627 0.373 0.000
H25.2 Senile cataract, morgagnian type
0.627 0.373 0.000
M25.56 Pain in joint (Lower leg)
0.626 0.374 0.000
I47 Paroxysmal tachycardia
0.626 0.374 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.626 0.374 0.000
K51.5 Mucosal proctocolitis
0.625 0.375 0.000
K51.4 Pseudopolyposis of colon
0.625 0.375 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.625 0.375 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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