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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs148838820
log Bayes Factor = 16.8302
Chromosome 3   position 157,221,258  (GRCh37) Explore rs148838820 on Ensembl!
Variant rs148838820 is part of Cluster X0203

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
C79 Secondary malignant neoplasm of other sites
0.995 0.005 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.993 0.007 0.000
I51 Complications and ill-defined descriptions of heart disease
0.993 0.007 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.990 0.010 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.987 0.013 0.000
F17.1 Harmful use
0.987 0.013 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.983 0.017 0.000
I20 Angina pectoris
0.977 0.023 0.000
I25 Chronic ischaemic heart disease
0.975 0.025 0.000
Chapter XX External causes of morbidity and mortality
0.974 0.026 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.974 0.026 0.000
I21 Acute myocardial infarction
0.973 0.027 0.000
C78.7 Secondary malignant neoplasm of liver
0.962 0.038 0.000
J09-J18 Influenza and pneumonia
0.961 0.039 0.000
I51.8 Other ill-defined heart diseases
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.957 0.043 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.954 0.046 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.953 0.047 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.952 0.048 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.951 0.048 0.000
J95-J99 Other diseases of the respiratory system
0.950 0.050 0.000
Chapter VIII Diseases of the ear and mastoid process
0.950 0.050 0.000
I35 Nonrheumatic aortic valve disorders
0.949 0.051 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.948 0.052 0.000
C15-C26 Malignant neoplasms of digestive organs
0.943 0.057 0.000
I51.7 Cardiomegaly
0.941 0.059 0.000
I26 Pulmonary embolism
0.938 0.062 0.000
J90-J94 Other diseases of pleura
0.938 0.062 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.935 0.065 0.000
J18 Pneumonia, organism unspecified
0.927 0.073 0.000
I46 Cardiac arrest
0.926 0.074 0.000
J30-J39 Other diseases of upper respiratory tract
0.926 0.074 0.000
J98 Other respiratory disorders
0.921 0.079 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.917 0.083 0.000
C34 Malignant neoplasm of bronchus and lung
0.917 0.083 0.000
I21.9 Acute myocardial infarction, unspecified
0.916 0.084 0.000
I20.9 Angina pectoris, unspecified
0.914 0.086 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.912 0.088 0.000
J90 Pleural effusion, not elsewhere classified
0.907 0.093 0.000
J18.1 Lobar pneumonia, unspecified
0.904 0.096 0.000
I38 Endocarditis, valve unspecified
0.903 0.097 0.000
I77 Other disorders of arteries and arterioles
0.903 0.097 0.000
Y43 Primarily systemic agents
0.901 0.099 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.897 0.103 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.893 0.107 0.000
J98.1 Pulmonary collapse
0.889 0.111 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.888 0.112 0.000
H65-H75 Diseases of middle ear and mastoid
0.885 0.115 0.000
I50 Heart failure
0.881 0.119 0.000
C78.2 Secondary malignant neoplasm of pleura
0.872 0.128 0.000
I46.0 Cardiac arrest with successful resuscitation
0.864 0.136 0.000
J36 Peritonsillar abscess
0.864 0.136 0.000
I31 Other diseases of pericardium
0.852 0.148 0.000
C34.9 Bronchus or lung, unspecified
0.851 0.149 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.850 0.150 0.000
Chapter VI Diseases of the nervous system
0.850 0.150 0.000
C77.8 Lymph nodes of multiple regions
0.848 0.152 0.000
J60-J70 Lung diseases due to external agents
0.844 0.156 0.000
C77.0 Lymph nodes of head, face and neck
0.844 0.156 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.844 0.156 0.000
I20.8 Other forms of angina pectoris
0.842 0.158 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.840 0.160 0.000
H80-H83 Diseases of inner ear
0.839 0.161 0.000
I49 Other cardiac arrhythmias
0.837 0.163 0.000
Y40 Systemic antibiotics
0.837 0.163 0.000
I20.0 Unstable angina
0.834 0.166 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.833 0.167 0.000
Y43.3 Other antineoplastic drugs
0.832 0.168 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.829 0.171 0.000
I27 Other pulmonary heart diseases
0.829 0.171 0.000
S80-S89 Injuries to the knee and lower leg
0.824 0.176 0.000
J20-J22 Other acute lower respiratory infections
0.820 0.180 0.000
J35 Chronic diseases of tonsils and adenoids
0.820 0.180 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.820 0.180 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.819 0.181 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.815 0.185 0.000
E70-E90 Metabolic disorders
0.812 0.188 0.000
I44 Atrioventricular and left bundle-branch block
0.811 0.189 0.000
D46 Myelodysplastic syndromes
0.805 0.195 0.000
V20-V29 Motorcycle rider injured in transport accident
0.805 0.195 0.000
W20-W49 Exposure to inanimate mechanical forces
0.804 0.195 0.000
E20-E35 Disorders of other endocrine glands
0.805 0.195 0.000
I50.0 Congestive heart failure
0.804 0.196 0.000
I51.0 Cardiac septal defect, acquired
0.804 0.196 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.803 0.197 0.000
C77.1 Intrathoracic lymph nodes
0.802 0.198 0.000
Chapter VII Diseases of the eye and adnexa
0.800 0.200 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.798 0.202 0.000
I37 Pulmonary valve disorders
0.797 0.203 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.796 0.204 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.795 0.205 0.000
I72 Other aneurysm
0.795 0.205 0.000
C64-C68 Malignant neoplasms of urinary tract
0.794 0.206 0.000
I77.8 Other specified disorders of arteries and arterioles
0.794 0.206 0.000
G90-G99 Other disorders of the nervous system
0.790 0.210 0.000
C25 Malignant neoplasm of pancreas
0.789 0.211 0.000
J18.0 Bronchopneumonia, unspecified
0.788 0.212 0.000
F17.2 Dependence syndrome
0.788 0.212 0.000
H66 Suppurative and unspecified otitis media
0.787 0.213 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.787 0.213 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.786 0.214 0.000
F30-F39 Mood [affective] disorders
0.786 0.214 0.000
I31.3 Pericardial effusion (noninflammatory)
0.785 0.215 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.785 0.215 0.000
C77.9 Lymph node, unspecified
0.784 0.216 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.783 0.217 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.781 0.219 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.781 0.219 0.000
I77.1 Stricture of artery
0.781 0.219 0.000
I35.9 Aortic valve disorder, unspecified
0.777 0.223 0.000
I35.1 Aortic (valve) insufficiency
0.776 0.224 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.775 0.225 0.000
C78.0 Secondary malignant neoplasm of lung
0.774 0.226 0.000
C18 Malignant neoplasm of colon
0.766 0.234 0.000
I05-I09 Chronic rheumatic heart diseases
0.766 0.234 0.000
C34.0 Main bronchus
0.766 0.234 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.765 0.235 0.000
I74 Arterial embolism and thrombosis
0.764 0.236 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.764 0.236 0.000
I35.0 Aortic (valve) stenosis
0.764 0.236 0.000
I34 Nonrheumatic mitral valve disorders
0.763 0.237 0.000
F60-F69 Disorders of adult personality and behaviour
0.762 0.238 0.000
V80-V89 Other land transport accidents
0.762 0.238 0.000
Y43.1 Antineoplastic antimetabolites
0.761 0.239 0.000
C34.3 Lower lobe, bronchus or lung
0.760 0.240 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.760 0.240 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.760 0.240 0.000
I36 Nonrheumatic tricuspid valve disorders
0.759 0.240 0.000
J98.6 Disorders of diaphragm
0.758 0.242 0.000
H81 Disorders of vestibular function
0.758 0.242 0.000
H60-H62 Diseases of external ear
0.756 0.244 0.000
H72 Perforation of tympanic membrane
0.755 0.245 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.753 0.247 0.000
I49.5 Sick sinus syndrome
0.752 0.248 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.750 0.250 0.000
E83 Disorders of mineral metabolism
0.750 0.250 0.000
J69 Pneumonitis due to solids and liquids
0.748 0.252 0.000
I25.5 Ischaemic cardiomyopathy
0.748 0.252 0.000
J10 Influenza due to identified influenza virus
0.745 0.255 0.000
Q80-Q89 Other congenital malformations
0.744 0.256 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.742 0.258 0.000
T66-T78 Other and unspecified effects of external causes
0.738 0.262 0.000
I22 Subsequent myocardial infarction
0.738 0.262 0.000
S81 Open wound of lower leg
0.736 0.264 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.735 0.265 0.000
T18 Foreign body in alimentary tract
0.735 0.265 0.000
I33 Acute and subacute endocarditis
0.734 0.266 0.000
S70-S79 Injuries to the hip and thigh
0.733 0.267 0.000
J39 Other diseases of upper respiratory tract
0.733 0.267 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.732 0.268 0.000
S20-S29 Injuries to the thorax
0.731 0.269 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
I71 Aortic aneurysm and dissection
0.729 0.271 0.000
Y52 Agents primarily affecting the cardiovascular system
0.729 0.271 0.000
D48.1 Connective and other soft tissue
0.728 0.272 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.728 0.272 0.000
J98.4 Other disorders of lung
0.728 0.272 0.000
Q60-Q64 Congenital malformations of the urinary system
0.727 0.273 0.000
C21 Malignant neoplasm of anus and anal canal
0.723 0.277 0.000
F99-F99 Unspecified mental disorder
0.722 0.277 0.000
Chapter I Certain infectious and parasitic diseases
0.722 0.278 0.000
I73 Other peripheral vascular diseases
0.722 0.278 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.720 0.280 0.000
C77.2 Intra-abdominal lymph nodes
0.720 0.280 0.000
Chapter XXII Codes for special purposes
0.718 0.281 0.000
H74 Other disorders of middle ear and mastoid
0.718 0.282 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
C15 Malignant neoplasm of oesophagus
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.715 0.285 0.000
C79.6 Secondary malignant neoplasm of ovary
0.714 0.286 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.714 0.286 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.714 0.286 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.713 0.286 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.712 0.288 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.712 0.288 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.712 0.288 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.712 0.288 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.712 0.288 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.712 0.288 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.712 0.288 0.000
F11 Mental and behavioural disorders due to use of opioids
0.712 0.288 0.000
I51.6 Cardiovascular disease, unspecified
0.712 0.288 0.000
I51.5 Myocardial degeneration
0.712 0.288 0.000
I51.4 Myocarditis, unspecified
0.712 0.288 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.712 0.288 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.712 0.288 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.712 0.288 0.000
F17.9 Unspecified mental and behavioural disorder
0.710 0.290 0.000
F17.8 Other mental and behavioural disorders
0.710 0.290 0.000
F17.7 Residual and late-onset psychotic disorder
0.710 0.290 0.000
F17.6 Amnesic syndrome
0.710 0.290 0.000
F17.5 Psychotic disorder
0.710 0.290 0.000
F17.4 Withdrawal state with delirium
0.710 0.290 0.000
F17.3 Withdrawal state
0.710 0.290 0.000
F17.0 Acute intoxication
0.710 0.290 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.710 0.290 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.709 0.291 0.000
Q50-Q56 Congenital malformations of genital organs
0.708 0.292 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.708 0.292 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.708 0.292 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.708 0.292 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.708 0.292 0.000
C16 Malignant neoplasm of stomach
0.706 0.294 0.000
H81.0 Meniere's disease
0.704 0.296 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.704 0.296 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.703 0.297 0.000
C80 Malignant neoplasm without specification of site
0.702 0.297 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
I46.9 Cardiac arrest, unspecified
0.702 0.298 0.000
R06 Abnormalities of breathing
0.701 0.299 0.000
C79.2 Secondary malignant neoplasm of skin
0.701 0.299 0.000
F32 Depressive episode
0.701 0.299 0.000
Y40.8 Other systemic antibiotics
0.700 0.300 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.699 0.301 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.699 0.301 0.000
C60-C63 Malignant neoplasms of male genital organs
0.699 0.301 0.000
I25.6 Silent myocardial ischaemia
0.699 0.301 0.000
I25.4 Coronary artery aneurysm
0.699 0.301 0.000
I25.3 Aneurysm of heart
0.699 0.301 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.698 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.698 0.301 0.000
Y10-Y34 Event of undetermined intent
0.698 0.301 0.000
Y00-Y09 Assault
0.698 0.301 0.000
X85-X99 Assault
0.698 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.301 0.000
X50-X57 Overexertion, travel and privation
0.698 0.301 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.698 0.301 0.000
X30-X39 Exposure to forces of nature
0.698 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.698 0.301 0.000
X10-X19 Contact with heat and hot substances
0.698 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.698 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.698 0.301 0.000
W75-W84 Other accidental threats to breathing
0.698 0.301 0.000
W65-W74 Accidental drowning and submersion
0.698 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.698 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.698 0.301 0.000
V95-V97 Air and space transport accidents
0.698 0.301 0.000
V90-V94 Water transport accidents
0.698 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.698 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.698 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.698 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.698 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.301 0.000
I28 Other diseases of pulmonary vessels
0.698 0.302 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.697 0.302 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.697 0.302 0.000
J93 Pneumothorax
0.696 0.304 0.000
D45 Polycythaemia vera
0.694 0.306 0.000
C18.2 Ascending colon
0.694 0.306 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
G93 Other disorders of brain
0.694 0.306 0.000
I77.6 Arteritis, unspecified
0.694 0.306 0.000
I20.1 Angina pectoris with documented spasm
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
I27.2 Other secondary pulmonary hypertension
0.692 0.308 0.000
E27 Other disorders of adrenal gland
0.691 0.309 0.000
Y40.0 Penicillins
0.691 0.309 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.690 0.310 0.000
J17 Pneumonia in diseases classified elsewhere
0.689 0.311 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.689 0.311 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.689 0.311 0.000
J12 Viral pneumonia, not elsewhere classified
0.689 0.311 0.000
J11 Influenza, virus not identified
0.689 0.311 0.000
J14 Pneumonia due to Haemophilus influenzae
0.689 0.311 0.000
J09 Influenza due to certain identified influenza virus
0.689 0.311 0.000
S32 Fracture of lumbar spine and pelvis
0.689 0.311 0.000
H66.9 Otitis media, unspecified
0.688 0.312 0.000
W00-W19 Falls
0.688 0.312 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.688 0.312 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.688 0.312 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.686 0.313 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.686 0.313 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.686 0.314 0.000
H73 Other disorders of tympanic membrane
0.686 0.314 0.000
H00 Hordeolum and chalazion
0.686 0.314 0.000
D47.1 Chronic myeloproliferative disease
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.684 0.316 0.000
Y58 Bacterial vaccines
0.684 0.316 0.000
Y57 Other and unspecified drugs and medicaments
0.684 0.316 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.684 0.316 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.684 0.316 0.000
Y48 Anaesthetics and therapeutic gases
0.684 0.316 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.684 0.316 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.684 0.316 0.000
T33-T35 Frostbite
0.683 0.316 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.683 0.316 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.683 0.316 0.000
T00-T07 Injuries involving multiple body regions
0.683 0.316 0.000
S10-S19 Injuries to the neck
0.683 0.316 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.684 0.316 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.683 0.317 0.000
R00 Abnormalities of heart beat
0.683 0.317 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.682 0.318 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.682 0.318 0.000
C32 Malignant neoplasm of larynx
0.682 0.318 0.000
C31 Malignant neoplasm of accessory sinuses
0.682 0.318 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.682 0.318 0.000
C37 Malignant neoplasm of thymus
0.682 0.318 0.000
C33 Malignant neoplasm of trachea
0.682 0.318 0.000
J91 Pleural effusion in conditions classified elsewhere
0.682 0.318 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.681 0.319 0.000
J96 Respiratory failure, not elsewhere classified
0.681 0.319 0.000
I44.2 Atrioventricular block, complete
0.681 0.319 0.000
S50-S59 Injuries to the elbow and forearm
0.680 0.319 0.000
I35.8 Other aortic valve disorders
0.680 0.320 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.680 0.320 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.680 0.320 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.680 0.320 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.680 0.320 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.680 0.320 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.680 0.320 0.000
L40-L45 Papulosquamous disorders
0.680 0.320 0.000
G91 Hydrocephalus
0.679 0.321 0.000
J69.0 Pneumonitis due to food and vomit
0.679 0.321 0.000
R26 Abnormalities of gait and mobility
0.679 0.321 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.679 0.321 0.000
I72.4 Aneurysm of artery of lower extremity
0.678 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.676 0.324 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.676 0.324 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.676 0.324 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.676 0.324 0.000
C17 Malignant neoplasm of small intestine
0.676 0.324 0.000
C23 Malignant neoplasm of gallbladder
0.676 0.324 0.000
F10.1 Harmful use
0.676 0.324 0.000
J94 Other pleural conditions
0.676 0.324 0.000
I49.4 Other and unspecified premature depolarisation
0.675 0.325 0.000
O36 Maternal care for other known or suspected foetal problems
0.675 0.325 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.673 0.327 0.000
S31 Open wound of abdomen, lower back and pelvis
0.672 0.328 0.000
T17 Foreign body in respiratory tract
0.671 0.329 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.669 0.331 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.669 0.331 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.668 0.332 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.668 0.332 0.000
C09 Malignant neoplasm of tonsil
0.668 0.332 0.000
I50.1 Left ventricular failure
0.667 0.333 0.000
C51-C58 Malignant neoplasms of female genital organs
0.667 0.333 0.000
S90-S99 Injuries to the ankle and foot
0.666 0.334 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.666 0.334 0.000
J18.8 Other pneumonia, organism unspecified
0.665 0.335 0.000
J18.2 Hypostatic pneumonia, unspecified
0.665 0.335 0.000
J22 Unspecified acute lower respiratory infection
0.664 0.336 0.000
I46.1 Sudden cardiac death, so described
0.664 0.336 0.000
J37 Chronic laryngitis and laryngotracheitis
0.664 0.336 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.664 0.336 0.000
T79-T79 Certain early complications of trauma
0.664 0.336 0.000
C67 Malignant neoplasm of bladder
0.663 0.337 0.000
C73 Malignant neoplasm of thyroid gland
0.663 0.337 0.000
C01 Malignant neoplasm of base of tongue
0.661 0.339 0.000
L20-L30 Dermatitis and eczema
0.661 0.339 0.000
J98.9 Respiratory disorder, unspecified
0.660 0.340 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.660 0.340 0.000
J98.3 Compensatory emphysema
0.660 0.340 0.000
J98.2 Interstitial emphysema
0.660 0.340 0.000
J98.8 Other specified respiratory disorders
0.660 0.340 0.000
D48.0 Bone and articular cartilage
0.659 0.341 0.000
I51.9 Heart disease, unspecified
0.659 0.341 0.000
S00-S09 Injuries to the head
0.658 0.341 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.658 0.342 0.000
T18.1 Foreign body in oesophagus
0.657 0.342 0.000
C34.8 Overlapping lesion of bronchus and lung
0.657 0.343 0.000
C34.2 Middle lobe, bronchus or lung
0.657 0.343 0.000
Y44 Agents primarily affecting blood constituents
0.657 0.343 0.000
I44.3 Other and unspecified atrioventricular block
0.656 0.344 0.000
E10-E14 Diabetes mellitus
0.656 0.344 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.654 0.346 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.654 0.346 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.654 0.346 0.000
Q35-Q37 Cleft lip and cleft palate
0.654 0.346 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.654 0.346 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.654 0.346 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.346 0.000
C45 Mesothelioma
0.654 0.346 0.000
W22 Striking against or struck by other objects
0.653 0.347 0.000
C25.0 Head of pancreas
0.653 0.347 0.000
I27.0 Primary pulmonary hypertension
0.652 0.348 0.000
I37.1 Pulmonary valve insufficiency
0.651 0.349 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.650 0.350 0.000
R00.2 Palpitations
0.649 0.351 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.649 0.351 0.000
G12 Spinal muscular atrophy and related syndromes
0.648 0.352 0.000
H00.1 Chalazion
0.648 0.352 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.648 0.352 0.000
J35.1 Hypertrophy of tonsils
0.647 0.353 0.000
I77.5 Necrosis of artery
0.647 0.353 0.000
I77.4 Coeliac artery compression syndrome
0.647 0.353 0.000
I77.3 Arterial fibromuscular dysplasia
0.647 0.353 0.000
I77.2 Rupture of artery
0.647 0.353 0.000
I77.0 Arteriovenous fistula, acquired
0.647 0.353 0.000
Y43.9 Primarily systemic agent, unspecified
0.646 0.354 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.646 0.354 0.000
Y43.6 Enzymes, not elsewhere classified
0.646 0.354 0.000
Y43.5 Acidifying and alkalising agents
0.646 0.354 0.000
Y43.4 Immunosuppressive agents
0.646 0.354 0.000
Y43.2 Antineoplastic natural products
0.646 0.354 0.000
Y43.0 Antiallergic and antiemetic drugs
0.646 0.354 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.645 0.355 0.000
C77.4 Inguinal and lower limb lymph nodes
0.643 0.357 0.000
E40-E46 Malnutrition
0.640 0.360 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.640 0.360 0.000
C34.1 Upper lobe, bronchus or lung
0.639 0.360 0.000
L50-L54 Urticaria and erythema
0.639 0.361 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.638 0.361 0.000
F20 Schizophrenia
0.638 0.362 0.000
G95 Other diseases of spinal cord
0.637 0.363 0.000
I25.1 Atherosclerotic heart disease
0.637 0.363 0.000
F29 Unspecified nonorganic psychosis
0.635 0.365 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.635 0.365 0.000
H70 Mastoiditis and related conditions
0.635 0.365 0.000
H69 Other disorders of Eustachian tube
0.635 0.365 0.000
H68 Eustachian salpingitis and obstruction
0.635 0.365 0.000
H67 Otitis media in diseases classified elsewhere
0.635 0.365 0.000
I70 Atherosclerosis
0.635 0.365 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.635 0.365 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.634 0.366 0.000
V10-V19 Pedal cyclist injured in transport accident
0.633 0.366 0.000
I49.1 Atrial premature depolarisation
0.633 0.367 0.000
E83.1 Disorders of iron metabolism
0.632 0.368 0.000
E87.6 Hypokalaemia
0.631 0.369 0.000
J20 Acute bronchitis
0.630 0.370 0.000
I45 Other conduction disorders
0.630 0.370 0.000
S81.9 Open wound of lower leg, part unspecified
0.629 0.371 0.000
J31.0 Chronic rhinitis
0.629 0.371 0.000
H66.3 Other chronic suppurative otitis media
0.629 0.371 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.629 0.371 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.628 0.372 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.627 0.373 0.000
I07 Rheumatic tricuspid valve diseases
0.626 0.373 0.000
J35.0 Chronic tonsillitis
0.626 0.374 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.625 0.375 0.000
D48.5 Skin
0.624 0.376 0.000
E22 Hyperfunction of pituitary gland
0.623 0.377 0.000
R06.8 Other and unspecified abnormalities of breathing
0.622 0.378 0.000
E23 Hypofunction and other disorders of pituitary gland
0.622 0.378 0.000
W25 Contact with sharp glass
0.621 0.378 0.000
E83.5 Disorders of calcium metabolism
0.621 0.379 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.620 0.380 0.000
E83.3 Disorders of phosphorus metabolism
0.618 0.382 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.618 0.382 0.000
H05 Disorders of orbit
0.617 0.383 0.000
O40 Polyhydramnios
0.616 0.384 0.000
C77.5 Intrapelvic lymph nodes
0.616 0.384 0.000
G70-G73 Diseases of myoneural junction and muscle
0.616 0.384 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.614 0.386 0.000
H72.0 Central perforation of tympanic membrane
0.613 0.387 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.613 0.387 0.000
R06.0 Dyspnoea
0.613 0.387 0.000
F22 Persistent delusional disorders
0.612 0.387 0.000
I47 Paroxysmal tachycardia
0.612 0.388 0.000
H83 Other diseases of inner ear
0.612 0.388 0.000
H10-H13 Disorders of conjunctiva
0.612 0.388 0.000
E88 Other metabolic disorders
0.611 0.389 0.000
I31.8 Other specified diseases of pericardium
0.611 0.389 0.000
I31.2 Haemopericardium, not elsewhere classified
0.611 0.389 0.000
I31.1 Chronic constrictive pericarditis
0.611 0.389 0.000
I31.0 Chronic adhesive pericarditis
0.611 0.389 0.000
Q21 Congenital malformations of cardiac septa
0.610 0.390 0.000
H61 Other disorders of external ear
0.610 0.390 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.610 0.390 0.000
O85-O92 Complications predominantly related to the puerperium
0.609 0.390 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.609 0.391 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.609 0.391 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.609 0.391 0.000
C25.9 Pancreas, unspecified
0.608 0.392 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.608 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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