TreeWAS – Variant ID: rs16849553

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I10 Essential (primary) hypertension	0.001	0.999
I10-I15 Hypertensive diseases	0.001	0.999
D64.9 Anaemia, unspecified	0.001	0.999
Chapter IX Diseases of the circulatory system	0.001	0.999
# Top node	0.001	0.999
D64 Other anaemias	0.001	0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.999
D60-D64 Aplastic and other anaemias	0.001	0.999
I15 Secondary hypertension	0.001	0.999
I13 Hypertensive heart and renal disease	0.001	0.999
I12 Hypertensive renal disease	0.001	0.999
I11 Hypertensive heart disease	0.001	0.999
Chapter XI Diseases of the digestive system	0.001	0.999
I95-I99 Other and unspecified disorders of the circulatory system	0.001	0.999
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.001	0.999
I70-I79 Diseases of arteries, arterioles and capillaries	0.001	0.999
I60-I69 Cerebrovascular diseases	0.001	0.999
I30-I52 Other forms of heart disease	0.001	0.999
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.999
I20-I25 Ischaemic heart diseases	0.001	0.999
I05-I09 Chronic rheumatic heart diseases	0.001	0.999
I00-I02 Acute rheumatic fever	0.001	0.999
Chapter XXII Codes for special purposes	0.001	0.999
Chapter XXI Factors influencing health status and contact with health services	0.001	0.999
Chapter XX External causes of morbidity and mortality	0.001	0.999
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.001	0.999
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.001	0.999
Chapter XVI Certain conditions originating in the perinatal period	0.001	0.999
Chapter XV Pregnancy, childbirth and the puerperium	0.001	0.999
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.001	0.999
Chapter XIV Diseases of the genitourinary system	0.001	0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.001	0.999
Chapter XII Diseases of the skin and subcutaneous tissue	0.001	0.999
Chapter X Diseases of the respiratory system	0.001	0.999
Chapter VIII Diseases of the ear and mastoid process	0.001	0.999
Chapter VII Diseases of the eye and adnexa	0.001	0.999
Chapter VI Diseases of the nervous system	0.001	0.999
Chapter V Mental and behavioural disorders	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999
Chapter II Neoplasms	0.001	0.999
Chapter I Certain infectious and parasitic diseases	0.001	0.999
D64.8 Other specified anaemias	0.001	0.999
D64.4 Congenital dyserythropoietic anaemia	0.001	0.999
D64.3 Other sideroblastic anaemias	0.001	0.999
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.001	0.999
D64.1 Secondary sideroblastic anaemia due to disease	0.001	0.999
D64.0 Hereditary sideroblastic anaemia	0.001	0.999
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.999
D61 Other aplastic anaemias	0.001	0.999
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999
D62 Acute posthaemorrhagic anaemia	0.001	0.999
D80-D89 Certain disorders involving the immune mechanism	0.001	0.999
D70-D77 Other diseases of blood and blood-forming organs	0.001	0.999
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.001	0.999
D55-D59 Haemolytic anaemias	0.001	0.999
D50-D53 Nutritional anaemias	0.001	0.999
K55-K64 Other diseases of intestines	0.001	0.999
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.999
I11.0 Hypertensive heart disease with (congestive) heart failure	0.001	0.999
I12.9 Hypertensive renal disease without renal failure	0.001	0.999
I12.0 Hypertensive renal disease with renal failure	0.001	0.999
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.999
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.001	0.999
I13.1 Hypertensive heart and renal disease with renal failure	0.001	0.999
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.001	0.999
I15.9 Seconday hypertension, unspecified	0.001	0.999
I15.8 Other secondary hypertension	0.001	0.999
I15.2 Hypertension secondary to endocrine disorders	0.001	0.999
I15.1 Hypertension secondary to other renal disorders	0.001	0.999
I15.0 Renovascular hypertension	0.001	0.999
I02 Rheumatic chorea	0.001	0.999
I01 Rheumatic fever with heart involvement	0.001	0.999
I00 Rheumatic fever without mention of heart involvement	0.001	0.999
I09 Other rheumatic heart diseases	0.001	0.999
I08 Multiple valve diseases	0.001	0.999
I07 Rheumatic tricuspid valve diseases	0.001	0.999
I06 Rheumatic aortic valve diseases	0.001	0.999
I05 Rheumatic mitral valve diseases	0.001	0.999
I25 Chronic ischaemic heart disease	0.001	0.999
I24 Other acute ischaemic heart diseases	0.001	0.999
I23 Certain current complications following acute myocardial infarction	0.001	0.999
I22 Subsequent myocardial infarction	0.001	0.999
I21 Acute myocardial infarction	0.001	0.999
I20 Angina pectoris	0.001	0.999
I28 Other diseases of pulmonary vessels	0.001	0.999
I27 Other pulmonary heart diseases	0.001	0.999
I26 Pulmonary embolism	0.001	0.999
I52 Other heart disorders in diseases classified elsewhere	0.001	0.999
I51 Complications and ill-defined descriptions of heart disease	0.001	0.999
I50 Heart failure	0.001	0.999
I49 Other cardiac arrhythmias	0.001	0.999
I48 Atrial fibrillation and flutter	0.001	0.999
I47 Paroxysmal tachycardia	0.001	0.999
I46 Cardiac arrest	0.001	0.999
I45 Other conduction disorders	0.001	0.999
I44 Atrioventricular and left bundle-branch block	0.001	0.999
I43 Cardiomyopathy in diseases classified elsewhere	0.001	0.999
I42 Cardiomyopathy	0.001	0.999
I41 Myocarditis in diseases classified elsewhere	0.001	0.999
I40 Acute myocarditis	0.001	0.999
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.001	0.999
I37 Pulmonary valve disorders	0.001	0.999
I36 Nonrheumatic tricuspid valve disorders	0.001	0.999
I35 Nonrheumatic aortic valve disorders	0.001	0.999
I34 Nonrheumatic mitral valve disorders	0.001	0.999
I33 Acute and subacute endocarditis	0.001	0.999
I32 Pericarditis in diseases classified elsewhere	0.001	0.999
I31 Other diseases of pericardium	0.001	0.999
I30 Acute pericarditis	0.001	0.999
I38 Endocarditis, valve unspecified	0.001	0.999
I69 Sequelae of cerebrovascular disease	0.001	0.999
I68 Cerebrovascular disorders in diseases classified elsewhere	0.001	0.999
I67 Other cerebrovascular diseases	0.001	0.999
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.001	0.999
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.001	0.999
I63 Cerebral infarction	0.001	0.999
I62 Other nontraumatic intracranial haemorrhage	0.001	0.999
I61 Intracerebral haemorrhage	0.001	0.999
I60 Subarachnoid haemorrhage	0.001	0.999
I64 Stroke, not specified as haemorrhage or infarction	0.001	0.999
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.999
I78 Diseases of capillaries	0.001	0.999
I77 Other disorders of arteries and arterioles	0.001	0.999
I74 Arterial embolism and thrombosis	0.001	0.999
I73 Other peripheral vascular diseases	0.001	0.999
I72 Other aneurysm	0.001	0.999
I71 Aortic aneurysm and dissection	0.001	0.999
I70 Atherosclerosis	0.001	0.999
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.999
I88 Nonspecific lymphadenitis	0.001	0.999
I87 Other disorders of veins	0.001	0.999
I86 Varicose veins of other sites	0.001	0.999
I85 Oesophageal varices	0.001	0.999
I84 Haemorrhoids	0.001	0.999
I83 Varicose veins of lower extremities	0.001	0.999
I82 Other venous embolism and thrombosis	0.001	0.999
I80 Phlebitis and thrombophlebitis	0.001	0.999
I81 Portal vein thrombosis	0.001	0.999
I98 Other disorders of circulatory system in diseases classified elsewhere	0.001	0.999
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.999
I95 Hypotension	0.001	0.999
I99 Other and unspecified disorders of circulatory system	0.001	0.999
K57 Diverticular disease of intestine	0.001	0.999
E70-E90 Metabolic disorders	0.001	0.999
E65-E68 Obesity and other hyperalimentation	0.001	0.999
E50-E64 Other nutritional deficiencies	0.001	0.999
E40-E46 Malnutrition	0.001	0.999
E20-E35 Disorders of other endocrine glands	0.001	0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.999
E10-E14 Diabetes mellitus	0.001	0.999
E00-E07 Disorders of thyroid gland	0.001	0.999
K90-K93 Other diseases of the digestive system	0.001	0.999
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.001	0.999
K70-K77 Diseases of liver	0.001	0.999
K65-K67 Diseases of peritoneum	0.001	0.999
K50-K52 Noninfective enteritis and colitis	0.001	0.999
K40-K46 Hernia	0.001	0.999
K35-K38 Diseases of appendix	0.001	0.999
K20-K31 Diseases of oesophagus, stomach and duodenum	0.001	0.999
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.001	0.999
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999
D60.8 Other acquired pure red cell aplasias	0.001	0.999
D60.1 Transient acquired pure red cell aplasia	0.001	0.999
D60.0 Chronic acquired pure red cell aplasia	0.001	0.999
D61.9 Aplastic anaemia, unspecified	0.001	0.999
D61.8 Other specified aplastic anaemias	0.001	0.999
D61.3 Idiopathic aplastic anaemia	0.001	0.999
D61.2 Aplastic anaemia due to other external agents	0.001	0.999
D61.1 Drug-induced aplastic anaemia	0.001	0.999
D61.0 Constitutional aplastic anaemia	0.001	0.999
D63.8 Anaemia in other chronic diseases classified elsewhere	0.001	0.999
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999
D63.0 Anaemia in neoplastic disease	0.001	0.999
K57.3 Diverticular disease of large intestine without perforation or abscess	0.001	0.999
D53 Other nutritional anaemias	0.001	0.999
D52 Folate deficiency anaemia	0.001	0.999
D51 Vitamin B12 deficiency anaemia	0.001	0.999
D50 Iron deficiency anaemia	0.001	0.999
D59 Acquired haemolytic anaemia	0.001	0.999
D58 Other hereditary haemolytic anaemias	0.001	0.999
D57 Sickle-cell disorders	0.001	0.999
D56 Thalassaemia	0.001	0.999
D55 Anaemia due to enzyme disorders	0.001	0.999
D69 Purpura and other haemorrhagic conditions	0.001	0.999
D68 Other coagulation defects	0.001	0.999
D67 Hereditary factor IX deficiency	0.001	0.999
D66 Hereditary factor VIII deficiency	0.001	0.999
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.001	0.999
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.001	0.999
D75 Other diseases of blood and blood-forming organs	0.001	0.999
D74 Methaemoglobinaemia	0.001	0.999
D73 Diseases of spleen	0.001	0.999
D72 Other disorders of white blood cells	0.001	0.999
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.001	0.999
D71 Functional disorders of polymorphonuclear neutrophils	0.001	0.999
D70 Agranulocytosis	0.001	0.999
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999
D86 Sarcoidosis	0.001	0.999
D84 Other immunodeficiencies	0.001	0.999
D83 Common variable immunodeficiency	0.001	0.999
D82 Immunodeficiency associated with other major defects	0.001	0.999
D81 Combined immunodeficiencies	0.001	0.999
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999
K64 Haemorrhoids and perianal venous thrombosis	0.001	0.999
K63 Other diseases of intestine	0.001	0.999
K62 Other diseases of anus and rectum	0.001	0.999
K61 Abscess of anal and rectal regions	0.001	0.999
K60 Fissure and fistula of anal and rectal regions	0.001	0.999
K59 Other functional intestinal disorders	0.001	0.999
K58 Irritable bowel syndrome	0.001	0.999
K56 Paralytic ileus and intestinal obstruction without hernia	0.001	0.999
K55 Vascular disorders of intestine	0.001	0.999
B99-B99 Other infectious diseases	0.001	0.999
B95-B98 Bacterial, viral and other infectious agents	0.001	0.999
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.999
B85-B89 Pediculosis, acariasis and other infestations	0.001	0.999
B65-B83 Helminthiases	0.001	0.999
B50-B64 Protozoal diseases	0.001	0.999
B35-B49 Mycoses	0.001	0.999
B25-B34 Other viral diseases	0.001	0.999
B20-B24 Human immunodeficiency virus [HIV] disease	0.001	0.999
B15-B19 Viral hepatitis	0.001	0.999
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.001	0.999
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.001	0.999
A80-A89 Viral infections of the central nervous system	0.001	0.999
A75-A79 Rickettsioses	0.001	0.999
A70-A74 Other diseases caused by chlamydiae	0.001	0.999
A65-A69 Other spirochaetal diseases	0.001	0.999
A50-A64 Infections with a predominantly sexual mode of transmission	0.001	0.999
A30-A49 Other bacterial diseases	0.001	0.999
A20-A28 Certain zoonotic bacterial diseases	0.001	0.999
A15-A19 Tuberculosis	0.001	0.999
A00-A09 Intestinal infectious diseases	0.001	0.999
D37-D48 Neoplasms of uncertain or unknown behaviour	0.001	0.999
D10-D36 Benign neoplasms	0.001	0.999
D00-D09 In situ neoplasms	0.001	0.999
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.001	0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.001	0.999
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.001	0.999
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.999
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.999
C64-C68 Malignant neoplasms of urinary tract	0.001	0.999
C60-C63 Malignant neoplasms of male genital organs	0.001	0.999
C51-C58 Malignant neoplasms of female genital organs	0.001	0.999
C50-C50 Malignant neoplasm of breast	0.001	0.999
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999
C43-C44 Melanoma and other malignant neoplasms of skin	0.001	0.999
C40-C41 Malignant neoplasms of bone and articular cartilage	0.001	0.999
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.001	0.999
C15-C26 Malignant neoplasms of digestive organs	0.001	0.999
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.001	0.999
F99-F99 Unspecified mental disorder	0.001	0.999
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.001	0.999
F80-F89 Disorders of psychological development	0.001	0.999
F70-F79 Mental retardation	0.001	0.999
F60-F69 Disorders of adult personality and behaviour	0.001	0.999
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.001	0.999
F40-F48 Neurotic, stress-related and somatoform disorders	0.001	0.999
F30-F39 Mood [affective] disorders	0.001	0.999
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.001	0.999
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999
G90-G99 Other disorders of the nervous system	0.001	0.999
G80-G83 Cerebral palsy and other paralytic syndromes	0.001	0.999
G70-G73 Diseases of myoneural junction and muscle	0.001	0.999
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.001	0.999
G50-G59 Nerve, nerve root and plexus disorders	0.001	0.999
G40-G47 Episodic and paroxysmal disorders	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.001	0.999
G30-G32 Other degenerative diseases of the nervous system	0.001	0.999
G20-G26 Extrapyramidal and movement disorders	0.001	0.999
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.001	0.999
G00-G09 Inflammatory diseases of the central nervous system	0.001	0.999
H55-H59 Other disorders of eye and adnexa	0.001	0.999
H53-H54 Visual disturbances and blindness	0.001	0.999
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.001	0.999
H46-H48 Disorders of optic nerve and visual pathways	0.001	0.999
H43-H45 Disorders of vitreous body and globe	0.001	0.999
H40-H42 Glaucoma	0.001	0.999
H30-H36 Disorders of choroid and retina	0.001	0.999
H25-H28 Disorders of lens	0.001	0.999
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.001	0.999
H10-H13 Disorders of conjunctiva	0.001	0.999
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.001	0.999
H90-H95 Other disorders of ear	0.001	0.999
H80-H83 Diseases of inner ear	0.001	0.999
H65-H75 Diseases of middle ear and mastoid	0.001	0.999
H60-H62 Diseases of external ear	0.001	0.999
J95-J99 Other diseases of the respiratory system	0.001	0.999
J90-J94 Other diseases of pleura	0.001	0.999
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.001	0.999
J80-J84 Other respiratory diseases principally affecting the interstitium	0.001	0.999
J60-J70 Lung diseases due to external agents	0.001	0.999
J40-J47 Chronic lower respiratory diseases	0.001	0.999
J30-J39 Other diseases of upper respiratory tract	0.001	0.999
J20-J22 Other acute lower respiratory infections	0.001	0.999
J09-J18 Influenza and pneumonia	0.001	0.999
J00-J06 Acute upper respiratory infections	0.001	0.999
L80-L99 Other disorders of the skin and subcutaneous tissue	0.001	0.999
L60-L75 Disorders of skin appendages	0.001	0.999
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.001	0.999
L50-L54 Urticaria and erythema	0.001	0.999
L40-L45 Papulosquamous disorders	0.001	0.999
L20-L30 Dermatitis and eczema	0.001	0.999
L10-L14 Bullous disorders	0.001	0.999
L00-L08 Infections of the skin and subcutaneous tissue	0.001	0.999
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.001	0.999
M91-M94 Chondropathies	0.001	0.999
M86-M90 Other osteopathies	0.001	0.999
M80-M85 Disorders of bone density and structure	0.001	0.999
M70-M79 Other soft tissue disorders	0.001	0.999
M65-M68 Disorders of synovium and tendon	0.001	0.999
M60-M63 Disorders of muscles	0.001	0.999
M50-M54 Other dorsopathies	0.001	0.999
M45-M49 Spondylopathies	0.001	0.999
M40-M43 Deforming dorsopathies	0.001	0.999
M20-M25 Other joint disorders	0.001	0.999
M15-M19 Arthrosis	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.001	0.999
M00-M03 Infectious arthropathies	0.001	0.999
N99-N99 Other disorders of the genitourinary system	0.001	0.999
N80-N98 Noninflammatory disorders of female genital tract	0.001	0.999
N70-N77 Inflammatory diseases of female pelvic organs	0.001	0.999
N60-N64 Disorders of breast	0.001	0.999
N40-N51 Diseases of male genital organs	0.001	0.999
N30-N39 Other diseases of urinary system	0.001	0.999
N25-N29 Other disorders of kidney and ureter	0.001	0.999
N20-N23 Urolithiasis	0.001	0.999
N17-N19 Renal failure	0.001	0.999
N10-N16 Renal tubulo-interstitial diseases	0.001	0.999
N00-N08 Glomerular diseases	0.001	0.999
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.001	0.999
T79-T79 Certain early complications of trauma	0.001	0.999
T66-T78 Other and unspecified effects of external causes	0.001	0.999
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999
T33-T35 Frostbite	0.001	0.999
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.001	0.999
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.999
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.999
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.999
T00-T07 Injuries involving multiple body regions	0.001	0.999
S90-S99 Injuries to the ankle and foot	0.001	0.999
S80-S89 Injuries to the knee and lower leg	0.001	0.999
S70-S79 Injuries to the hip and thigh	0.001	0.999
S60-S69 Injuries to the wrist and hand	0.001	0.999
S50-S59 Injuries to the elbow and forearm	0.001	0.999
S40-S49 Injuries to the shoulder and upper arm	0.001	0.999
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.001	0.999
S20-S29 Injuries to the thorax	0.001	0.999
S10-S19 Injuries to the neck	0.001	0.999
S00-S09 Injuries to the head	0.001	0.999
O94-O99 Other obstetric conditions, not elsewhere classified	0.001	0.999
O85-O92 Complications predominantly related to the puerperium	0.001	0.999
O80-O84 Delivery	0.001	0.999
O60-O75 Complications of labour and delivery	0.001	0.999
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.001	0.999
O20-O29 Other maternal disorders predominantly related to pregnancy	0.001	0.999
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.001	0.999
O00-O08 Pregnancy with abortive outcome	0.001	0.999
P90-P96 Other disorders originating in the perinatal period	0.001	0.999
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.001	0.999
P75-P78 Digestive system disorders of fetus and newborn	0.001	0.999
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.001	0.999
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.001	0.999
P35-P39 Infections specific to the perinatal period	0.001	0.999
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.001	0.999
P10-P15 Birth trauma	0.001	0.999
P05-P08 Disorders related to length of gestation and fetal growth	0.001	0.999
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.001	0.999
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999
Q80-Q89 Other congenital malformations	0.001	0.999
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999
Q50-Q56 Congenital malformations of genital organs	0.001	0.999
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.999
Q35-Q37 Cleft lip and cleft palate	0.001	0.999
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.999
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.999
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999
R95-R99 Ill-defined and unknown causes of mortality	0.001	0.999
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.001	0.999
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.001	0.999
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.001	0.999
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.001	0.999
R50-R69 General symptoms and signs	0.001	0.999
R47-R49 Symptoms and signs involving speech and voice	0.001	0.999
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.001	0.999
R30-R39 Symptoms and signs involving the urinary system	0.001	0.999
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.001	0.999
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.001	0.999
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.001	0.999
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.001	0.999
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.001	0.999
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.001	0.999
Y60-Y69 Misadventures to patients during surgical and medical care	0.001	0.999
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.001	0.999
Y35-Y36 Legal intervention and operations of war	0.001	0.999
Y10-Y34 Event of undetermined intent	0.001	0.999
Y00-Y09 Assault	0.001	0.999
X85-X99 Assault	0.001	0.999
X60-X84 Intentional self-harm	0.001	0.999
X58-X59 Accidental exposure to other and unspecified factors	0.001	0.999
X50-X57 Overexertion, travel and privation	0.001	0.999
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.999
X30-X39 Exposure to forces of nature	0.001	0.999
X20-X29 Contact with venomous animals and plants	0.001	0.999
X10-X19 Contact with heat and hot substances	0.001	0.999
X00-X09 Exposure to smoke, fire and flames	0.001	0.999
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.001	0.999
W75-W84 Other accidental threats to breathing	0.001	0.999
W65-W74 Accidental drowning and submersion	0.001	0.999
W50-W64 Exposure to animate mechanical forces	0.001	0.999
W20-W49 Exposure to inanimate mechanical forces	0.001	0.999
W00-W19 Falls	0.001	0.999
V98-V99 Other and unspecified transport accidents	0.001	0.999
V95-V97 Air and space transport accidents	0.001	0.999
V90-V94 Water transport accidents	0.001	0.999
V80-V89 Other land transport accidents	0.001	0.999
V70-V79 Bus occupant injured in transport accident	0.001	0.999
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.001	0.999
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.001	0.999
V40-V49 Car occupant injured in transport accident	0.001	0.999
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.001	0.999
V20-V29 Motorcycle rider injured in transport accident	0.001	0.999
V10-V19 Pedal cyclist injured in transport accident	0.001	0.999
V01-V09 Pedestrian injured in transport accident	0.001	0.999
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.001	0.999
Z70-Z76 Persons encountering health services in other circumstances	0.001	0.999
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.001	0.999
Z40-Z54 Persons encountering health services for specific procedures and health care	0.001	0.999
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.001	0.999
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.001	0.999
Z00-Z13 Persons encountering health services for examination and investigation	0.001	0.999
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.001	0.999
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.001	0.999
I01.9 Acute rheumatic heart disease, unspecified	0.001	0.999
I01.8 Other acute rheumatic heart disease	0.001	0.999
I01.2 Acute rheumatic myocarditis	0.001	0.999
I01.1 Acute rheumatic endocarditis	0.001	0.999
I01.0 Acute rheumatic pericarditis	0.001	0.999
I02.9 Rheumatic chorea without heart involvement	0.001	0.999
I02.0 Rheumatic chorea with heart involvement	0.001	0.999
I05.9 Mitral valve disease, unspecified	0.001	0.999
I05.8 Other mitral valve diseases	0.001	0.999
I05.2 Mitral stenosis with insufficiency	0.001	0.999
I05.1 Rheumatic mitral insufficiency	0.001	0.999
I05.0 Mitral stenosis	0.001	0.999
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.999
I06.8 Other rheumatic aortic valve diseases	0.001	0.999
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.999
I06.1 Rheumatic aortic insufficiency	0.001	0.999
I06.0 Rheumatic aortic stenosis	0.001	0.999
I07.9 Tricuspid valve disease, unspecified	0.001	0.999
I07.8 Other tricuspid valve diseases	0.001	0.999
I07.2 Tricuspid stenosis with insufficiency	0.001	0.999
I07.1 Tricuspid insufficiency	0.001	0.999
I07.0 Tricuspid stenosis	0.001	0.999
I08.9 Multiple valve disease, unspecified	0.001	0.999
I08.8 Other multiple valve diseases	0.001	0.999
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.999
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.999
I08.1 Disorders of both mitral and tricuspid valves	0.001	0.999
I08.0 Disorders of both mitral and aortic valves	0.001	0.999
I09.9 Rheumatic heart disease, unspecified	0.001	0.999
I09.8 Other specified rheumatic heart diseases	0.001	0.999
I09.2 Chronic rheumatic pericarditis	0.001	0.999
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.999
I09.0 Rheumatic myocarditis	0.001	0.999
I20.9 Angina pectoris, unspecified	0.001	0.999
I20.8 Other forms of angina pectoris	0.001	0.999
I20.1 Angina pectoris with documented spasm	0.001	0.999
I20.0 Unstable angina	0.001	0.999
I21.X Presumed acute myicardial infaction (unconfirmed)	0.001	0.999
I21.9 Acute myocardial infarction, unspecified	0.001	0.999
I21.4 Acute subendocardial myocardial infarction	0.001	0.999
I21.3 Acute transmural myocardial infarction of unspecified site	0.001	0.999
I21.2 Acute transmural myocardial infarction of other sites	0.001	0.999
I21.1 Acute transmural myocardial infarction of inferior wall	0.001	0.999
I21.0 Acute transmural myocardial infarction of anterior wall	0.001	0.999
I22.9 Subsequent myocardial infarction of unspecified site	0.001	0.999
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999
I22.1 Subsequent myocardial infarction of inferior wall	0.001	0.999
I22.0 Subsequent myocardial infarction of anterior wall	0.001	0.999
I23.8 Other current complications following acute myocardial infarction	0.001	0.999
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.001	0.999
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.001	0.999
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.001	0.999
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.001	0.999
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.001	0.999
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.001	0.999
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.001	0.999
I24.9 Acute ischaemic heart disease, unspecified	0.001	0.999
I24.8 Other forms of acute ischaemic heart disease	0.001	0.999
I24.1 Dressler's syndrome	0.001	0.999

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations