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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16871289
log Bayes Factor = <0.0001
Chromosome 4   position 21,511,383  (GRCh37) Explore rs16871289 on Ensembl!
Variant rs16871289 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z37.0 Single live birth
0.002 0.997 0.000
I84 Haemorrhoids
0.002 0.997 0.000
I84.6 Residual haemorrhoidal skin tags
0.002 0.998 0.000
I84.9 Unspecified haemorrhoids without complication
0.002 0.998 0.000
I84.2 Internal haemorrhoids without complication
0.002 0.998 0.000
Z37 Outcome of delivery
0.002 0.998 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.002 0.998 0.000
I84.8 Unspecified haemorrhoids with other complications
0.002 0.998 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.002 0.998 0.000
I84.5 External haemorrhoids without complication
0.002 0.998 0.000
I84.4 External haemorrhoids with other complications
0.002 0.998 0.000
I84.3 External thrombosed haemorrhoids
0.002 0.998 0.000
I84.1 Internal haemorrhoids with other complications
0.002 0.998 0.000
I84.0 Internal thrombosed haemorrhoids
0.002 0.998 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.002 0.998 0.000
Chapter IX Diseases of the circulatory system
0.002 0.998 0.000
Z37.9 Outcome of delivery unspecified
0.002 0.998 0.000
Z37.7 Other multiple births, all stillborn
0.002 0.998 0.000
Z37.6 Other multiple births, some liveborn
0.002 0.998 0.000
Z37.5 Other multiple births, all liveborn
0.002 0.998 0.000
Z37.4 Twins, both stillborn
0.002 0.998 0.000
Z37.3 Twins, one liveborn and one stillborn
0.002 0.998 0.000
Z37.2 Twins, both liveborn
0.002 0.998 0.000
Z37.1 Single stillbirth
0.002 0.998 0.000
J18.1 Lobar pneumonia, unspecified
0.002 0.998 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.002 0.998 0.000
I88 Nonspecific lymphadenitis
0.002 0.998 0.000
I87 Other disorders of veins
0.002 0.998 0.000
I86 Varicose veins of other sites
0.002 0.998 0.000
I85 Oesophageal varices
0.002 0.998 0.000
I82 Other venous embolism and thrombosis
0.002 0.998 0.000
I80 Phlebitis and thrombophlebitis
0.002 0.998 0.000
I81 Portal vein thrombosis
0.002 0.998 0.000
I83 Varicose veins of lower extremities
0.002 0.998 0.000
J18 Pneumonia, organism unspecified
0.002 0.998 0.000
J09-J18 Influenza and pneumonia
0.001 0.998 0.000
# Top node
0.002 0.998 0.000
Z30 Contraceptive management
0.001 0.998 0.000
I10-I15 Hypertensive diseases
0.002 0.998 0.000
Chapter X Diseases of the respiratory system
0.002 0.998 0.000
Z39 Postpartum care and examination
0.001 0.998 0.000
Z38 Liveborn infants according to place of birth
0.001 0.998 0.000
Z36 Antenatal screening
0.001 0.998 0.000
Z35 Supervision of high-risk pregnancy
0.001 0.998 0.000
Z34 Supervision of normal pregnancy
0.001 0.998 0.000
Z32 Pregnancy examination and test
0.001 0.998 0.000
Z31 Procreative management
0.001 0.998 0.000
Z33 Pregnant state, incidental
0.001 0.998 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.001 0.998 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.001 0.998 0.000
I60-I69 Cerebrovascular diseases
0.001 0.998 0.000
I30-I52 Other forms of heart disease
0.001 0.998 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.998 0.000
I05-I09 Chronic rheumatic heart diseases
0.001 0.998 0.000
I00-I02 Acute rheumatic fever
0.001 0.998 0.000
Chapter XXI Factors influencing health status and contact with health services
0.002 0.998 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.001 0.998 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.001 0.998 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.001 0.998 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.001 0.998 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.001 0.998 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.001 0.998 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.001 0.998 0.000
I82.8 Embolism and thrombosis of other specified veins
0.001 0.998 0.000
I82.3 Embolism and thrombosis of renal vein
0.001 0.998 0.000
I82.2 Embolism and thrombosis of vena cava
0.001 0.998 0.000
I82.1 Thrombophlebitis migrans
0.001 0.998 0.000
I82.0 Budd-Chiari syndrome
0.001 0.998 0.000
I85.9 Oesophageal varices without bleeding
0.001 0.998 0.000
I85.0 Oesophageal varices with bleeding
0.001 0.998 0.000
I86.8 Varicose veins of other specified sites
0.001 0.998 0.000
I86.4 Gastric varices
0.001 0.998 0.000
I86.3 Vulval varices
0.001 0.998 0.000
I86.2 Pelvic varices
0.001 0.998 0.000
I86.1 Scrotal varices
0.001 0.998 0.000
I86.0 Sublingual varices
0.001 0.998 0.000
I87.9 Disorder of vein, unspecified
0.001 0.998 0.000
I87.8 Other specified disorders of veins
0.001 0.998 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.001 0.998 0.000
I87.1 Compression of vein
0.001 0.998 0.000
I87.0 Postphlebitic syndrome
0.001 0.998 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.001 0.998 0.000
I88.8 Other nonspecific lymphadenitis
0.001 0.998 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.001 0.998 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.001 0.998 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.001 0.998 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.001 0.998 0.000
I89.1 Lymphangitis
0.001 0.998 0.000
I89.0 Lymphoedema, not elsewhere classified
0.001 0.998 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.001 0.998 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.001 0.998 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.001 0.998 0.000
I20-I25 Ischaemic heart diseases
0.001 0.998 0.000
Chapter XX External causes of morbidity and mortality
0.001 0.998 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.001 0.998 0.000
J18.9 Pneumonia, unspecified
0.001 0.998 0.000
J18.8 Other pneumonia, organism unspecified
0.001 0.998 0.000
J18.2 Hypostatic pneumonia, unspecified
0.001 0.998 0.000
J18.0 Bronchopneumonia, unspecified
0.001 0.998 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.001 0.999 0.000
Chapter VII Diseases of the eye and adnexa
0.001 0.999 0.000
Chapter VI Diseases of the nervous system
0.001 0.999 0.000
Z30.2 Sterilisation
0.001 0.999 0.000
J17 Pneumonia in diseases classified elsewhere
0.001 0.999 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.001 0.999 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.001 0.999 0.000
J12 Viral pneumonia, not elsewhere classified
0.001 0.999 0.000
J11 Influenza, virus not identified
0.001 0.999 0.000
J10 Influenza due to identified influenza virus
0.001 0.999 0.000
J14 Pneumonia due to Haemophilus influenzae
0.001 0.999 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.001 0.999 0.000
J09 Influenza due to certain identified influenza virus
0.001 0.999 0.000
Chapter XXII Codes for special purposes
0.001 0.999 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.001 0.999 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.001 0.999 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.001 0.999 0.000
Chapter XIV Diseases of the genitourinary system
0.001 0.999 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.001 0.999 0.000
Chapter VIII Diseases of the ear and mastoid process
0.001 0.999 0.000
Chapter I Certain infectious and parasitic diseases
0.001 0.999 0.000
Z30.9 Contraceptive management, unspecified
0.001 0.999 0.000
Z30.8 Other contraceptive management
0.001 0.999 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.001 0.999 0.000
Z30.4 Surveillance of contraceptive drugs
0.001 0.999 0.000
Z30.3 Menstrual extraction
0.001 0.999 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.001 0.999 0.000
Z30.0 General counselling and advice on contraception
0.001 0.999 0.000
Z31.9 Procreative management, unspecified
0.001 0.999 0.000
Z31.8 Other procreative management
0.001 0.999 0.000
Z31.6 General counselling and advice on procreation
0.001 0.999 0.000
Z31.5 Genetic counselling
0.001 0.999 0.000
Z31.4 Procreative investigation and testing
0.001 0.999 0.000
Z31.3 Other assisted fertilisation methods
0.001 0.999 0.000
Z31.2 In vitro fertilisation
0.001 0.999 0.000
Z31.1 Artifical insemination
0.001 0.999 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.001 0.999 0.000
Z32.9 Pregnancy confirmed (erroneous code. See Z321)
0.001 0.999 0.000
Z32.1 Pregnancy confirmed
0.001 0.999 0.000
Z32.0 Pregnancy, not (yet) confirmed
0.001 0.999 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.001 0.999 0.000
Z34.8 Supervision of other normal pregnancy
0.001 0.999 0.000
Z34.0 Supervision of normal first pregnancy
0.001 0.999 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.001 0.999 0.000
Z35.8 Supervision of other high-risk pregnancies
0.001 0.999 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.001 0.999 0.000
Z35.6 Supervision of very young primigravida
0.001 0.999 0.000
Z35.5 Supervision of elderly primigravida
0.001 0.999 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.001 0.999 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.001 0.999 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.001 0.999 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.001 0.999 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.001 0.999 0.000
Z36.9 Antenatal screening, unspecified
0.001 0.999 0.000
Z36.8 Other antenatal screening
0.001 0.999 0.000
Z36.5 Antenatal screening for isoimmunisation
0.001 0.999 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.001 0.999 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.001 0.999 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.001 0.999 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.001 0.999 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.001 0.999 0.000
Z38.8 Other multiple, unspecified as to place of birth
0.001 0.999 0.000
Z38.7 Other multiple, born outside hospital
0.001 0.999 0.000
Z38.6 Other multiple, born in hospital
0.001 0.999 0.000
Z38.5 Twin, unspecified as to place of birth
0.001 0.999 0.000
Z38.4 Twin, born outside hospital
0.001 0.999 0.000
Z38.3 Twin, born in hospital
0.001 0.999 0.000
Z38.2 Singleton, unspecified as to place of birth
0.001 0.999 0.000
Z38.1 Singleton, born outside hospital
0.001 0.999 0.000
Z38.0 Singleton, born in hospital
0.001 0.999 0.000
Z39.2 Routine postpartum follow-up
0.001 0.999 0.000
Z39.1 Care and examination of lactating mother
0.001 0.999 0.000
Z39.0 Care and examination immediately after delivery
0.001 0.999 0.000
I15 Secondary hypertension
0.001 0.999 0.000
I13 Hypertensive heart and renal disease
0.001 0.999 0.000
I12 Hypertensive renal disease
0.001 0.999 0.000
I11 Hypertensive heart disease
0.001 0.999 0.000
I10 Essential (primary) hypertension
0.001 0.999 0.000
J95-J99 Other diseases of the respiratory system
0.001 0.999 0.000
J90-J94 Other diseases of pleura
0.001 0.999 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.001 0.999 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.999 0.000
J60-J70 Lung diseases due to external agents
0.001 0.999 0.000
J30-J39 Other diseases of upper respiratory tract
0.001 0.999 0.000
J20-J22 Other acute lower respiratory infections
0.001 0.999 0.000
J00-J06 Acute upper respiratory infections
0.001 0.999 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.001 0.999 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.001 0.999 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.001 0.999 0.000
Chapter II Neoplasms
0.001 0.999 0.000
I02 Rheumatic chorea
0.001 0.999 0.000
I01 Rheumatic fever with heart involvement
0.001 0.999 0.000
I00 Rheumatic fever without mention of heart involvement
0.001 0.999 0.000
I09 Other rheumatic heart diseases
0.001 0.999 0.000
I08 Multiple valve diseases
0.001 0.999 0.000
I07 Rheumatic tricuspid valve diseases
0.001 0.999 0.000
I06 Rheumatic aortic valve diseases
0.001 0.999 0.000
I05 Rheumatic mitral valve diseases
0.001 0.999 0.000
I28 Other diseases of pulmonary vessels
0.001 0.999 0.000
I27 Other pulmonary heart diseases
0.001 0.999 0.000
I26 Pulmonary embolism
0.001 0.999 0.000
I52 Other heart disorders in diseases classified elsewhere
0.001 0.999 0.000
I51 Complications and ill-defined descriptions of heart disease
0.001 0.999 0.000
I50 Heart failure
0.001 0.999 0.000
I49 Other cardiac arrhythmias
0.001 0.999 0.000
I48 Atrial fibrillation and flutter
0.001 0.999 0.000
I47 Paroxysmal tachycardia
0.001 0.999 0.000
I46 Cardiac arrest
0.001 0.999 0.000
I45 Other conduction disorders
0.001 0.999 0.000
I44 Atrioventricular and left bundle-branch block
0.001 0.999 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.001 0.999 0.000
I42 Cardiomyopathy
0.001 0.999 0.000
I41 Myocarditis in diseases classified elsewhere
0.001 0.999 0.000
I40 Acute myocarditis
0.001 0.999 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.001 0.999 0.000
I37 Pulmonary valve disorders
0.001 0.999 0.000
I36 Nonrheumatic tricuspid valve disorders
0.001 0.999 0.000
I35 Nonrheumatic aortic valve disorders
0.001 0.999 0.000
I34 Nonrheumatic mitral valve disorders
0.001 0.999 0.000
I33 Acute and subacute endocarditis
0.001 0.999 0.000
I32 Pericarditis in diseases classified elsewhere
0.001 0.999 0.000
I31 Other diseases of pericardium
0.001 0.999 0.000
I30 Acute pericarditis
0.001 0.999 0.000
I38 Endocarditis, valve unspecified
0.001 0.999 0.000
I69 Sequelae of cerebrovascular disease
0.001 0.999 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.001 0.999 0.000
I67 Other cerebrovascular diseases
0.001 0.999 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.001 0.999 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.001 0.999 0.000
I63 Cerebral infarction
0.001 0.999 0.000
I62 Other nontraumatic intracranial haemorrhage
0.001 0.999 0.000
I61 Intracerebral haemorrhage
0.001 0.999 0.000
I60 Subarachnoid haemorrhage
0.001 0.999 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.001 0.999 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.999 0.000
I78 Diseases of capillaries
0.001 0.999 0.000
I77 Other disorders of arteries and arterioles
0.001 0.999 0.000
I74 Arterial embolism and thrombosis
0.001 0.999 0.000
I73 Other peripheral vascular diseases
0.001 0.999 0.000
I72 Other aneurysm
0.001 0.999 0.000
I71 Aortic aneurysm and dissection
0.001 0.999 0.000
I70 Atherosclerosis
0.001 0.999 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.001 0.999 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.999 0.000
I95 Hypotension
0.001 0.999 0.000
I99 Other and unspecified disorders of circulatory system
0.001 0.999 0.000
J40-J47 Chronic lower respiratory diseases
0.001 0.999 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.001 0.999 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.001 0.999 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.001 0.999 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.001 0.999 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.001 0.999 0.000
Chapter V Mental and behavioural disorders
0.001 0.999 0.000
N30-N39 Other diseases of urinary system
0.001 0.999 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.001 0.999 0.000
I24 Other acute ischaemic heart diseases
0.001 0.999 0.000
I23 Certain current complications following acute myocardial infarction
0.001 0.999 0.000
I22 Subsequent myocardial infarction
0.001 0.999 0.000
I21 Acute myocardial infarction
0.001 0.999 0.000
H25-H28 Disorders of lens
0.001 0.999 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.001 0.999 0.000
O60-O75 Complications of labour and delivery
0.001 0.999 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.001 0.999 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.001 0.999 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.001 0.999 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.001 0.999 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.001 0.999 0.000
Y35-Y36 Legal intervention and operations of war
0.001 0.999 0.000
Y10-Y34 Event of undetermined intent
0.001 0.999 0.000
Y00-Y09 Assault
0.001 0.999 0.000
X85-X99 Assault
0.001 0.999 0.000
X60-X84 Intentional self-harm
0.001 0.999 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.001 0.999 0.000
X50-X57 Overexertion, travel and privation
0.001 0.999 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.001 0.999 0.000
X30-X39 Exposure to forces of nature
0.001 0.999 0.000
X20-X29 Contact with venomous animals and plants
0.001 0.999 0.000
X10-X19 Contact with heat and hot substances
0.001 0.999 0.000
X00-X09 Exposure to smoke, fire and flames
0.001 0.999 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.001 0.999 0.000
W75-W84 Other accidental threats to breathing
0.001 0.999 0.000
W65-W74 Accidental drowning and submersion
0.001 0.999 0.000
W50-W64 Exposure to animate mechanical forces
0.001 0.999 0.000
W20-W49 Exposure to inanimate mechanical forces
0.001 0.999 0.000
W00-W19 Falls
0.001 0.999 0.000
V98-V99 Other and unspecified transport accidents
0.001 0.999 0.000
V95-V97 Air and space transport accidents
0.001 0.999 0.000
V90-V94 Water transport accidents
0.001 0.999 0.000
V80-V89 Other land transport accidents
0.001 0.999 0.000
V70-V79 Bus occupant injured in transport accident
0.001 0.999 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.001 0.999 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.001 0.999 0.000
V40-V49 Car occupant injured in transport accident
0.001 0.999 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.001 0.999 0.000
V20-V29 Motorcycle rider injured in transport accident
0.001 0.999 0.000
V10-V19 Pedal cyclist injured in transport accident
0.001 0.999 0.000
V01-V09 Pedestrian injured in transport accident
0.001 0.999 0.000
Z12 Special screening examination for neoplasms
0.001 0.999 0.000
G90-G99 Other disorders of the nervous system
0.001 0.999 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.001 0.999 0.000
G70-G73 Diseases of myoneural junction and muscle
0.001 0.999 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.001 0.999 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.001 0.999 0.000
G40-G47 Episodic and paroxysmal disorders
0.001 0.999 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.001 0.999 0.000
G30-G32 Other degenerative diseases of the nervous system
0.001 0.999 0.000
G20-G26 Extrapyramidal and movement disorders
0.001 0.999 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.001 0.999 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.001 0.999 0.000
H55-H59 Other disorders of eye and adnexa
0.001 0.999 0.000
H53-H54 Visual disturbances and blindness
0.001 0.999 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.001 0.999 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.001 0.999 0.000
H43-H45 Disorders of vitreous body and globe
0.001 0.999 0.000
H40-H42 Glaucoma
0.001 0.999 0.000
H30-H36 Disorders of choroid and retina
0.001 0.999 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.001 0.999 0.000
H10-H13 Disorders of conjunctiva
0.001 0.999 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.001 0.999 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.001 0.999 0.000
O85-O92 Complications predominantly related to the puerperium
0.001 0.999 0.000
O80-O84 Delivery
0.001 0.999 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.001 0.999 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.001 0.999 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.001 0.999 0.000
O00-O08 Pregnancy with abortive outcome
0.001 0.999 0.000
R30-R39 Symptoms and signs involving the urinary system
0.001 0.999 0.000
J10.8 Influenza with other manifestations, influenza virus identified
0.001 0.999 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.001 0.999 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.001 0.999 0.000
J11.8 Influenza with other manifestations, virus not identified
0.001 0.999 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.001 0.999 0.000
J11.0 Influenza with pneumonia, virus not identified
0.001 0.999 0.000
J12.9 Viral pneumonia, unspecified
0.001 0.999 0.000
J12.8 Other viral pneumonia
0.001 0.999 0.000
J12.3 Human metapneumovirus pneumonia
0.001 0.999 0.000
J12.2 Parainfluenza virus pneumonia
0.001 0.999 0.000
J12.1 Respiratory syncytial virus pneumonia
0.001 0.999 0.000
J12.0 Adenoviral pneumonia
0.001 0.999 0.000
J15.9 Bacterial pneumonia, unspecified
0.001 0.999 0.000
J15.8 Other bacterial pneumonia
0.001 0.999 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.001 0.999 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.001 0.999 0.000
J15.5 Pneumonia due to Escherichia coli
0.001 0.999 0.000
J15.4 Pneumonia due to other streptococci
0.001 0.999 0.000
J15.3 Pneumonia due to streptococcus, group B
0.001 0.999 0.000
J15.2 Pneumonia due to staphylococcus
0.001 0.999 0.000
J15.1 Pneumonia due to Pseudomonas
0.001 0.999 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.001 0.999 0.000
J16.8 Pneumonia due to other specified infectious organisms
0.001 0.999 0.000
J16.0 Chlamydial pneumonia
0.001 0.999 0.000
J17.8 Pneumonia in other diseases classified elsewhere
0.001 0.999 0.000
J17.3 Pneumonia in parasitic diseases
0.001 0.999 0.000
J17.2 Pneumonia in mycoses
0.001 0.999 0.000
J17.1 Pneumonia in viral diseases classified elsewhere
0.001 0.999 0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.001 0.999 0.000
I25 Chronic ischaemic heart disease
0.001 0.999 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.001 0.999 0.000
Z13 Special screening examination for other diseases and disorders
0.001 0.999 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.001 0.999 0.000
Z10 Routine general health check-up of defined subpopulation
0.001 0.999 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.001 0.999 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.001 0.999 0.000
Z04 Examination and observation for other reasons
0.001 0.999 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.001 0.999 0.000
Z02 Examination and encounter for administrative purposes
0.001 0.999 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.001 0.999 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.001 0.999 0.000
Z46 Fitting and adjustment of other devices
0.001 0.999 0.000
B99-B99 Other infectious diseases
0.001 0.999 0.000
B95-B98 Bacterial, viral and other infectious agents
0.001 0.999 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.001 0.999 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.001 0.999 0.000
B65-B83 Helminthiases
0.001 0.999 0.000
B50-B64 Protozoal diseases
0.001 0.999 0.000
B35-B49 Mycoses
0.001 0.999 0.000
B25-B34 Other viral diseases
0.001 0.999 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.001 0.999 0.000
B15-B19 Viral hepatitis
0.001 0.999 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.001 0.999 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.001 0.999 0.000
A80-A89 Viral infections of the central nervous system
0.001 0.999 0.000
A75-A79 Rickettsioses
0.001 0.999 0.000
A70-A74 Other diseases caused by chlamydiae
0.001 0.999 0.000
A65-A69 Other spirochaetal diseases
0.001 0.999 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.001 0.999 0.000
A30-A49 Other bacterial diseases
0.001 0.999 0.000
A20-A28 Certain zoonotic bacterial diseases
0.001 0.999 0.000
A15-A19 Tuberculosis
0.001 0.999 0.000
A00-A09 Intestinal infectious diseases
0.001 0.999 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.001 0.999 0.000
D00-D09 In situ neoplasms
0.001 0.999 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.001 0.999 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.001 0.999 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.001 0.999 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.001 0.999 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.001 0.999 0.000
C64-C68 Malignant neoplasms of urinary tract
0.001 0.999 0.000
C60-C63 Malignant neoplasms of male genital organs
0.001 0.999 0.000
C51-C58 Malignant neoplasms of female genital organs
0.001 0.999 0.000
C50-C50 Malignant neoplasm of breast
0.001 0.999 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.001 0.999 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.001 0.999 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.001 0.999 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.001 0.999 0.000
C15-C26 Malignant neoplasms of digestive organs
0.001 0.999 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.001 0.999 0.000
H90-H95 Other disorders of ear
0.001 0.999 0.000
H80-H83 Diseases of inner ear
0.001 0.999 0.000
H65-H75 Diseases of middle ear and mastoid
0.001 0.999 0.000
H60-H62 Diseases of external ear
0.001 0.999 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.001 0.999 0.000
L60-L75 Disorders of skin appendages
0.001 0.999 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.001 0.999 0.000
L50-L54 Urticaria and erythema
0.001 0.999 0.000
L40-L45 Papulosquamous disorders
0.001 0.999 0.000
L20-L30 Dermatitis and eczema
0.001 0.999 0.000
L10-L14 Bullous disorders
0.001 0.999 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.001 0.999 0.000
M20-M25 Other joint disorders
0.001 0.999 0.000
N99-N99 Other disorders of the genitourinary system
0.001 0.999 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.001 0.999 0.000
N60-N64 Disorders of breast
0.001 0.999 0.000
N25-N29 Other disorders of kidney and ureter
0.001 0.999 0.000
N20-N23 Urolithiasis
0.001 0.999 0.000
N17-N19 Renal failure
0.001 0.999 0.000
N10-N16 Renal tubulo-interstitial diseases
0.001 0.999 0.000
N00-N08 Glomerular diseases
0.001 0.999 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.001 0.999 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.001 0.999 0.000
T79-T79 Certain early complications of trauma
0.001 0.999 0.000
T66-T78 Other and unspecified effects of external causes
0.001 0.999 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.001 0.999 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.001 0.999 0.000
T33-T35 Frostbite
0.001 0.999 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.001 0.999 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.001 0.999 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.001 0.999 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.001 0.999 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.001 0.999 0.000
T00-T07 Injuries involving multiple body regions
0.001 0.999 0.000
S90-S99 Injuries to the ankle and foot
0.001 0.999 0.000
S80-S89 Injuries to the knee and lower leg
0.001 0.999 0.000
S70-S79 Injuries to the hip and thigh
0.001 0.999 0.000
S60-S69 Injuries to the wrist and hand
0.001 0.999 0.000
S50-S59 Injuries to the elbow and forearm
0.001 0.999 0.000
S40-S49 Injuries to the shoulder and upper arm
0.001 0.999 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.001 0.999 0.000
S20-S29 Injuries to the thorax
0.001 0.999 0.000
S10-S19 Injuries to the neck
0.001 0.999 0.000
S00-S09 Injuries to the head
0.001 0.999 0.000
P90-P96 Other disorders originating in the perinatal period
0.001 0.999 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.001 0.999 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.001 0.999 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.001 0.999 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.001 0.999 0.000
P35-P39 Infections specific to the perinatal period
0.001 0.999 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.001 0.999 0.000
P10-P15 Birth trauma
0.001 0.999 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.001 0.999 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.001 0.999 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.001 0.999 0.000
Q80-Q89 Other congenital malformations
0.001 0.999 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.001 0.999 0.000
Q60-Q64 Congenital malformations of the urinary system
0.001 0.999 0.000
Q50-Q56 Congenital malformations of genital organs
0.001 0.999 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.001 0.999 0.000
Q35-Q37 Cleft lip and cleft palate
0.001 0.999 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.001 0.999 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.001 0.999 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.001 0.999 0.000
Q00-Q07 Congenital malformations of the nervous system
0.001 0.999 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.001 0.999 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.001 0.999 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.999 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.001 0.999 0.000
I01.8 Other acute rheumatic heart disease
0.001 0.999 0.000
I01.2 Acute rheumatic myocarditis
0.001 0.999 0.000
I01.1 Acute rheumatic endocarditis
0.001 0.999 0.000
I01.0 Acute rheumatic pericarditis
0.001 0.999 0.000
I02.9 Rheumatic chorea without heart involvement
0.001 0.999 0.000
I02.0 Rheumatic chorea with heart involvement
0.001 0.999 0.000
I05.9 Mitral valve disease, unspecified
0.001 0.999 0.000
I05.8 Other mitral valve diseases
0.001 0.999 0.000
I05.2 Mitral stenosis with insufficiency
0.001 0.999 0.000
I05.1 Rheumatic mitral insufficiency
0.001 0.999 0.000
I05.0 Mitral stenosis
0.001 0.999 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.999 0.000
I06.8 Other rheumatic aortic valve diseases
0.001 0.999 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.001 0.999 0.000
I06.1 Rheumatic aortic insufficiency
0.001 0.999 0.000
I06.0 Rheumatic aortic stenosis
0.001 0.999 0.000
I07.9 Tricuspid valve disease, unspecified
0.001 0.999 0.000
I07.8 Other tricuspid valve diseases
0.001 0.999 0.000
I07.2 Tricuspid stenosis with insufficiency
0.001 0.999 0.000
I07.1 Tricuspid insufficiency
0.001 0.999 0.000
I07.0 Tricuspid stenosis
0.001 0.999 0.000
I08.9 Multiple valve disease, unspecified
0.001 0.999 0.000
I08.8 Other multiple valve diseases
0.001 0.999 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.001 0.999 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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