TreeWAS – Variant ID: rs16938910

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.397	0.603
Chapter IX Diseases of the circulatory system	0.386	0.614
Chapter XXI Factors influencing health status and contact with health services	0.373	0.627
Chapter XI Diseases of the digestive system	0.360	0.640
I10-I15 Hypertensive diseases	0.354	0.646
I20-I25 Ischaemic heart diseases	0.350	0.650
Z40-Z54 Persons encountering health services for specific procedures and health care	0.333	0.667
Chapter IV Endocrine, nutritional and metabolic diseases	0.333	0.667
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.332	0.668
I10 Essential (primary) hypertension	0.332	0.668
Chapter XII Diseases of the skin and subcutaneous tissue	0.315	0.685
I20 Angina pectoris	0.314	0.686
Chapter II Neoplasms	0.313	0.687
Chapter XIV Diseases of the genitourinary system	0.312	0.688
Chapter XX External causes of morbidity and mortality	0.311	0.689
K20-K31 Diseases of oesophagus, stomach and duodenum	0.310	0.690
Z53 Persons encountering health services for specifie procedures, not carried out	0.310	0.690
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.309	0.691
Chapter X Diseases of the respiratory system	0.301	0.699
Chapter V Mental and behavioural disorders	0.301	0.699
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.299	0.701
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.293	0.707
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.293	0.707
E70-E90 Metabolic disorders	0.291	0.709
Z53.8 Procedure not carried out for other reasons	0.288	0.712
Chapter XXII Codes for special purposes	0.285	0.715
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.285	0.715
Chapter XVI Certain conditions originating in the perinatal period	0.285	0.715
Chapter XV Pregnancy, childbirth and the puerperium	0.285	0.715
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.285	0.715
Chapter VIII Diseases of the ear and mastoid process	0.285	0.715
Chapter I Certain infectious and parasitic diseases	0.285	0.715
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.283	0.717
Chapter VI Diseases of the nervous system	0.280	0.720
Chapter VII Diseases of the eye and adnexa	0.279	0.721
K21 Gastro-oesophageal reflux disease	0.279	0.721
I25 Chronic ischaemic heart disease	0.278	0.722
I95-I99 Other and unspecified disorders of the circulatory system	0.277	0.723
I70-I79 Diseases of arteries, arterioles and capillaries	0.277	0.723
I60-I69 Cerebrovascular diseases	0.277	0.723
I30-I52 Other forms of heart disease	0.277	0.723
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.277	0.723
I05-I09 Chronic rheumatic heart diseases	0.277	0.723
I00-I02 Acute rheumatic fever	0.277	0.723
K55-K64 Other diseases of intestines	0.273	0.727
Z70-Z76 Persons encountering health services in other circumstances	0.273	0.727
K50-K52 Noninfective enteritis and colitis	0.272	0.728
I20.9 Angina pectoris, unspecified	0.272	0.728
Z96 Presence of other functional implants	0.269	0.731
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.267	0.732
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.267	0.732
Z00-Z13 Persons encountering health services for examination and investigation	0.267	0.732
Z92 Personal history of medical treatment	0.267	0.733
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.262	0.738
Z90 Acquired absence of organs, not elsewhere classified	0.262	0.738
K40-K46 Hernia	0.260	0.740
I20.0 Unstable angina	0.259	0.741
C60-C63 Malignant neoplasms of male genital organs	0.259	0.741
Z46 Fitting and adjustment of other devices	0.258	0.741
K90-K93 Other diseases of the digestive system	0.258	0.742
K70-K77 Diseases of liver	0.258	0.742
K65-K67 Diseases of peritoneum	0.258	0.742
K35-K38 Diseases of appendix	0.258	0.742
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.258	0.742
Z85 Personal history of malignant neoplasm	0.258	0.742
L80-L99 Other disorders of the skin and subcutaneous tissue	0.257	0.743
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.257	0.743
I15 Secondary hypertension	0.254	0.746
I13 Hypertensive heart and renal disease	0.254	0.746
I12 Hypertensive renal disease	0.254	0.746
I11 Hypertensive heart disease	0.254	0.746
I24 Other acute ischaemic heart diseases	0.251	0.749
I23 Certain current complications following acute myocardial infarction	0.251	0.749
I22 Subsequent myocardial infarction	0.251	0.749
I21 Acute myocardial infarction	0.251	0.749
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.250	0.750
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.248	0.752
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.245	0.754
K29 Gastritis and duodenitis	0.245	0.754
Z86 Personal history of certain other diseases	0.245	0.755
N20-N23 Urolithiasis	0.243	0.757
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.241	0.759
Z53.0 Procedure not carried out because of contraindication	0.241	0.759
E78.0 Pure hypercholesterolaemia	0.240	0.759
E10-E14 Diabetes mellitus	0.240	0.760
Z54 Convalescence	0.239	0.761
Z52 Donors of organs and tissues	0.239	0.761
Z50 Care involving use of rehabilitation procedures	0.239	0.761
Z49 Care involving dialysis	0.239	0.761
Z48 Other surgical follow-up care	0.239	0.761
Z47 Other orthopaedic follow-up care	0.239	0.761
Z45 Adjustment and management of implanted device	0.239	0.761
Z44 Fitting and adjustment of external prosthetic device	0.239	0.761
Z43 Attention to artificial openings	0.239	0.761
Z42 Follow-up care involving plastic surgery	0.239	0.761
Z41 Procedures for purposes other than remedying health state	0.239	0.761
Z40 Prophylactic surgery	0.239	0.761
E50-E64 Other nutritional deficiencies	0.239	0.761
E40-E46 Malnutrition	0.239	0.761
E20-E35 Disorders of other endocrine glands	0.239	0.761
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.239	0.761
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.238	0.761
Z98 Other postsurgical states	0.238	0.761
Z97 Presence of other devices	0.238	0.761
Z95 Presence of cardiac and vascular implants and grafts	0.238	0.761
Z94 Transplanted organ and tissue status	0.238	0.761
Z93 Artificial opening status	0.238	0.761
Z91 Personal history of risk-factors, not elsewhere classified	0.238	0.761
Z89 Acquired absence of limb	0.238	0.761
Z84 Family history of other conditions	0.238	0.761
Z83 Family history of other specific disorders	0.238	0.761
Z81 Family history of mental and behavioural disorders	0.238	0.761
Z80 Family history of malignant neoplasm	0.238	0.761
J20-J22 Other acute lower respiratory infections	0.237	0.763
I83 Varicose veins of lower extremities	0.236	0.763
M15-M19 Arthrosis	0.234	0.766
E65-E68 Obesity and other hyperalimentation	0.234	0.766
E00-E07 Disorders of thyroid gland	0.233	0.766
N80-N98 Noninflammatory disorders of female genital tract	0.233	0.767
M05-M14 Inflammatory polyarthropathies	0.232	0.768
F30-F39 Mood [affective] disorders	0.229	0.771
K80 Cholelithiasis	0.228	0.772
I25.9 Chronic ischaemic heart disease, unspecified	0.228	0.772
M20-M25 Other joint disorders	0.227	0.773
Z87 Personal history of other diseases and conditions	0.226	0.774
L60-L75 Disorders of skin appendages	0.226	0.774
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.226	0.774
L50-L54 Urticaria and erythema	0.226	0.774
L40-L45 Papulosquamous disorders	0.226	0.774
L20-L30 Dermatitis and eczema	0.226	0.774
L10-L14 Bullous disorders	0.226	0.774
L00-L08 Infections of the skin and subcutaneous tissue	0.226	0.774
N30-N39 Other diseases of urinary system	0.225	0.774
I20.8 Other forms of angina pectoris	0.225	0.775
I20.1 Angina pectoris with documented spasm	0.225	0.775
D37-D48 Neoplasms of uncertain or unknown behaviour	0.225	0.775
D00-D09 In situ neoplasms	0.225	0.775
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.225	0.775
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.225	0.775
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.225	0.775
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.225	0.775
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.225	0.775
C64-C68 Malignant neoplasms of urinary tract	0.225	0.775
C51-C58 Malignant neoplasms of female genital organs	0.225	0.775
C50-C50 Malignant neoplasm of breast	0.225	0.775
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.225	0.775
C43-C44 Melanoma and other malignant neoplasms of skin	0.225	0.775
C40-C41 Malignant neoplasms of bone and articular cartilage	0.225	0.775
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.225	0.775
C15-C26 Malignant neoplasms of digestive organs	0.225	0.775
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.225	0.775
N99-N99 Other disorders of the genitourinary system	0.224	0.776
N70-N77 Inflammatory diseases of female pelvic organs	0.224	0.776
N60-N64 Disorders of breast	0.224	0.776
N40-N51 Diseases of male genital organs	0.224	0.776
N25-N29 Other disorders of kidney and ureter	0.224	0.776
N17-N19 Renal failure	0.224	0.776
N10-N16 Renal tubulo-interstitial diseases	0.224	0.776
N00-N08 Glomerular diseases	0.224	0.776
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.223	0.776
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.223	0.777
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.223	0.777
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.223	0.777
Y60-Y69 Misadventures to patients during surgical and medical care	0.223	0.777
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.223	0.777
Y35-Y36 Legal intervention and operations of war	0.223	0.777
Y10-Y34 Event of undetermined intent	0.223	0.777
Y00-Y09 Assault	0.223	0.777
X85-X99 Assault	0.223	0.777
X60-X84 Intentional self-harm	0.223	0.777
X58-X59 Accidental exposure to other and unspecified factors	0.223	0.777
X50-X57 Overexertion, travel and privation	0.223	0.777
X40-X49 Accidental poisoning by and exposure to noxious substances	0.223	0.777
X30-X39 Exposure to forces of nature	0.223	0.777
X20-X29 Contact with venomous animals and plants	0.223	0.777
X10-X19 Contact with heat and hot substances	0.223	0.777
X00-X09 Exposure to smoke, fire and flames	0.223	0.777
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.223	0.777
W75-W84 Other accidental threats to breathing	0.223	0.777
W65-W74 Accidental drowning and submersion	0.223	0.777
W50-W64 Exposure to animate mechanical forces	0.223	0.777
W20-W49 Exposure to inanimate mechanical forces	0.223	0.777
W00-W19 Falls	0.223	0.777
V98-V99 Other and unspecified transport accidents	0.223	0.777
V95-V97 Air and space transport accidents	0.223	0.777
V90-V94 Water transport accidents	0.223	0.777
V80-V89 Other land transport accidents	0.223	0.777
V70-V79 Bus occupant injured in transport accident	0.223	0.777
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.223	0.777
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.223	0.777
V40-V49 Car occupant injured in transport accident	0.223	0.777
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.223	0.777
V20-V29 Motorcycle rider injured in transport accident	0.223	0.777
V10-V19 Pedal cyclist injured in transport accident	0.223	0.777
V01-V09 Pedestrian injured in transport accident	0.223	0.777
K31 Other diseases of stomach and duodenum	0.222	0.778
K28 Gastrojejunal ulcer	0.222	0.778
K27 Peptic ulcer, site unspecified	0.222	0.778
K26 Duodenal ulcer	0.222	0.778
K25 Gastric ulcer	0.222	0.778
K23 Disorders of oesophagus in diseases classified elsewhere	0.222	0.778
K22 Other diseases of oesophagus	0.222	0.778
Z53.9 Procedure not carried out, unspecified reason	0.222	0.778
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.222	0.778
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.222	0.778
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.222	0.778
M91-M94 Chondropathies	0.222	0.778
M86-M90 Other osteopathies	0.222	0.778
M80-M85 Disorders of bone density and structure	0.222	0.778
M70-M79 Other soft tissue disorders	0.222	0.778
M65-M68 Disorders of synovium and tendon	0.222	0.778
M60-M63 Disorders of muscles	0.222	0.778
M50-M54 Other dorsopathies	0.222	0.778
M45-M49 Spondylopathies	0.222	0.778
M40-M43 Deforming dorsopathies	0.222	0.778
M00-M03 Infectious arthropathies	0.222	0.778
C61 Malignant neoplasm of prostate	0.220	0.780
Z92.2 Personal history of long-term (current) use of other medicaments	0.220	0.780
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.220	0.780
R50-R69 General symptoms and signs	0.219	0.781
D60-D64 Aplastic and other anaemias	0.218	0.782
D10-D36 Benign neoplasms	0.216	0.784
J95-J99 Other diseases of the respiratory system	0.216	0.784
J90-J94 Other diseases of pleura	0.216	0.784
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.216	0.784
J80-J84 Other respiratory diseases principally affecting the interstitium	0.216	0.784
J60-J70 Lung diseases due to external agents	0.216	0.784
J30-J39 Other diseases of upper respiratory tract	0.216	0.784
J09-J18 Influenza and pneumonia	0.216	0.784
J00-J06 Acute upper respiratory infections	0.216	0.784
F99-F99 Unspecified mental disorder	0.216	0.784
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.216	0.784
F80-F89 Disorders of psychological development	0.216	0.784
F70-F79 Mental retardation	0.216	0.784
F60-F69 Disorders of adult personality and behaviour	0.216	0.784
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.216	0.784
F40-F48 Neurotic, stress-related and somatoform disorders	0.216	0.784
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.216	0.784
F00-F09 Organic, including symptomatic, mental disorders	0.216	0.784
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.215	0.785
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.214	0.785
I88 Nonspecific lymphadenitis	0.214	0.785
I87 Other disorders of veins	0.214	0.785
I86 Varicose veins of other sites	0.214	0.785
I85 Oesophageal varices	0.214	0.785
I84 Haemorrhoids	0.214	0.785
I82 Other venous embolism and thrombosis	0.214	0.785
I80 Phlebitis and thrombophlebitis	0.214	0.785
I81 Portal vein thrombosis	0.214	0.785
Z96.1 Presence of intraocular lens	0.213	0.786
K20 Oesophagitis	0.211	0.789
J40-J47 Chronic lower respiratory diseases	0.211	0.789
Z90.7 Acquired absence of genital organ(s)	0.211	0.789
R95-R99 Ill-defined and unknown causes of mortality	0.210	0.790
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.210	0.790
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.210	0.790
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.210	0.790
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.210	0.790
R47-R49 Symptoms and signs involving speech and voice	0.210	0.790
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.210	0.790
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.210	0.790
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.210	0.790
D80-D89 Certain disorders involving the immune mechanism	0.210	0.790
D70-D77 Other diseases of blood and blood-forming organs	0.210	0.790
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.210	0.790
D55-D59 Haemolytic anaemias	0.210	0.790
D50-D53 Nutritional anaemias	0.210	0.790
K52 Other non-infective gastro-enteritis and colitis	0.209	0.790
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.209	0.791
E88 Other metabolic disorders	0.209	0.791
E87 Other disorders of fluid, electrolyte and acid-base balance	0.209	0.791
E85 Amyloidosis	0.209	0.791
E84 Cystic fibrosis	0.209	0.791
E83 Disorders of mineral metabolism	0.209	0.791
E80 Disorders of porphyrin and bilirubin metabolism	0.209	0.791
E79 Disorders of purine and pyrimidine metabolism	0.209	0.791
E77 Disorders of glycoprotein metabolism	0.209	0.791
E76 Disorders of glycosaminoglycan metabolism	0.209	0.791
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.209	0.791
E74 Other disorders of carbohydrate metabolism	0.209	0.791
E73 Lactose intolerance	0.209	0.791
E72 Other disorders of amino-acid metabolism	0.209	0.791
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.209	0.791
E70 Disorders of aromatic amino-acid metabolism	0.209	0.791
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.209	0.791
E86 Volume depletion	0.209	0.791
K59 Other functional intestinal disorders	0.206	0.794
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.206	0.794
Z96.6 Presence of orthopaedic joint implants	0.206	0.794
Z46.6 Fitting and adjustment of urinary device	0.205	0.795
K63 Other diseases of intestine	0.205	0.795
B99-B99 Other infectious diseases	0.204	0.796
B95-B98 Bacterial, viral and other infectious agents	0.204	0.796
B90-B94 Sequelae of infectious and parasitic diseases	0.204	0.796
B85-B89 Pediculosis, acariasis and other infestations	0.204	0.796
B65-B83 Helminthiases	0.204	0.796
B50-B64 Protozoal diseases	0.204	0.796
B35-B49 Mycoses	0.204	0.796
B25-B34 Other viral diseases	0.204	0.796
B20-B24 Human immunodeficiency virus [HIV] disease	0.204	0.796
B15-B19 Viral hepatitis	0.204	0.796
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.204	0.796
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.204	0.796
A80-A89 Viral infections of the central nervous system	0.204	0.796
A75-A79 Rickettsioses	0.204	0.796
A70-A74 Other diseases caused by chlamydiae	0.204	0.796
A65-A69 Other spirochaetal diseases	0.204	0.796
A50-A64 Infections with a predominantly sexual mode of transmission	0.204	0.796
A30-A49 Other bacterial diseases	0.204	0.796
A20-A28 Certain zoonotic bacterial diseases	0.204	0.796
A15-A19 Tuberculosis	0.204	0.796
A00-A09 Intestinal infectious diseases	0.204	0.796
H90-H95 Other disorders of ear	0.204	0.796
H80-H83 Diseases of inner ear	0.204	0.796
H65-H75 Diseases of middle ear and mastoid	0.204	0.796
H60-H62 Diseases of external ear	0.204	0.796
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.204	0.796
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.204	0.796
T79-T79 Certain early complications of trauma	0.204	0.796
T66-T78 Other and unspecified effects of external causes	0.204	0.796
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.204	0.796
T36-T50 Poisoning by drugs, medicaments and biological substances	0.204	0.796
T33-T35 Frostbite	0.204	0.796
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.204	0.796
T26-T28 Burns and corrosions confined to eye and internal organs	0.204	0.796
T20-T25 Burns and corrosions of external body surface, specified by site	0.204	0.796
T15-T19 Effects of foreign body entering through natural orifice	0.204	0.796
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.204	0.796
T00-T07 Injuries involving multiple body regions	0.204	0.796
S90-S99 Injuries to the ankle and foot	0.204	0.796
S80-S89 Injuries to the knee and lower leg	0.204	0.796
S70-S79 Injuries to the hip and thigh	0.204	0.796
S60-S69 Injuries to the wrist and hand	0.204	0.796
S50-S59 Injuries to the elbow and forearm	0.204	0.796
S40-S49 Injuries to the shoulder and upper arm	0.204	0.796
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.204	0.796
S20-S29 Injuries to the thorax	0.204	0.796
S10-S19 Injuries to the neck	0.204	0.796
S00-S09 Injuries to the head	0.204	0.796
O94-O99 Other obstetric conditions, not elsewhere classified	0.204	0.796
O85-O92 Complications predominantly related to the puerperium	0.204	0.796
O80-O84 Delivery	0.204	0.796
O60-O75 Complications of labour and delivery	0.204	0.796
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.204	0.796
O20-O29 Other maternal disorders predominantly related to pregnancy	0.204	0.796
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.204	0.796
O00-O08 Pregnancy with abortive outcome	0.204	0.796
P90-P96 Other disorders originating in the perinatal period	0.204	0.796
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.204	0.796
P75-P78 Digestive system disorders of fetus and newborn	0.204	0.796
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.204	0.796
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.204	0.796
P35-P39 Infections specific to the perinatal period	0.204	0.796
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.204	0.796
P10-P15 Birth trauma	0.204	0.796
P05-P08 Disorders related to length of gestation and fetal growth	0.204	0.796
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.204	0.796
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.204	0.796
Q80-Q89 Other congenital malformations	0.204	0.796
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.204	0.796
Q60-Q64 Congenital malformations of the urinary system	0.204	0.796
Q50-Q56 Congenital malformations of genital organs	0.204	0.796
Q38-Q45 Other congenital malformations of the digestive system	0.204	0.796
Q35-Q37 Cleft lip and cleft palate	0.204	0.796
Q30-Q34 Congenital malformations of the respiratory system	0.204	0.796
Q20-Q28 Congenital malformations of the circulatory system	0.204	0.796
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.204	0.796
Q00-Q07 Congenital malformations of the nervous system	0.204	0.796
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.204	0.796
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.204	0.796
Z85.4 Personal history of malignant neoplasm of genital organs	0.204	0.796
R07 Pain in throat and chest	0.204	0.796
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.203	0.797
K86 Other diseases of pancreas	0.203	0.797
K85 Acute pancreatitis	0.203	0.797
K83 Other diseases of biliary tract	0.203	0.797
K82 Other diseases of gallbladder	0.203	0.797
K81 Cholecystitis	0.203	0.797
Z72 Problems related to lifestyle	0.201	0.799
G90-G99 Other disorders of the nervous system	0.201	0.799
G80-G83 Cerebral palsy and other paralytic syndromes	0.201	0.799
G70-G73 Diseases of myoneural junction and muscle	0.201	0.799
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.201	0.799
G40-G47 Episodic and paroxysmal disorders	0.201	0.799
G35-G37 Demyelinating diseases of the central nervous system	0.201	0.799
G30-G32 Other degenerative diseases of the nervous system	0.201	0.799
G20-G26 Extrapyramidal and movement disorders	0.201	0.799
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.201	0.799
G00-G09 Inflammatory diseases of the central nervous system	0.201	0.799
H55-H59 Other disorders of eye and adnexa	0.200	0.800
H53-H54 Visual disturbances and blindness	0.200	0.800
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.200	0.800
H46-H48 Disorders of optic nerve and visual pathways	0.200	0.800
H43-H45 Disorders of vitreous body and globe	0.200	0.800
H40-H42 Glaucoma	0.200	0.800
H30-H36 Disorders of choroid and retina	0.200	0.800
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.200	0.800
H10-H13 Disorders of conjunctiva	0.200	0.800
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.200	0.800
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.200	0.800
I25.8 Other forms of chronic ischaemic heart disease	0.200	0.800
I25.6 Silent myocardial ischaemia	0.200	0.800
I25.5 Ischaemic cardiomyopathy	0.200	0.800
I25.4 Coronary artery aneurysm	0.200	0.800
I25.3 Aneurysm of heart	0.200	0.800
I25.2 Old myocardial infarction	0.200	0.800
I25.0 Atherosclerotic cardiovascular disease, so described	0.200	0.800
K57 Diverticular disease of intestine	0.200	0.800
I02 Rheumatic chorea	0.199	0.801
I01 Rheumatic fever with heart involvement	0.199	0.801
I00 Rheumatic fever without mention of heart involvement	0.199	0.801
I09 Other rheumatic heart diseases	0.199	0.801
I08 Multiple valve diseases	0.199	0.801
I07 Rheumatic tricuspid valve diseases	0.199	0.801
I06 Rheumatic aortic valve diseases	0.199	0.801
I05 Rheumatic mitral valve diseases	0.199	0.801
I28 Other diseases of pulmonary vessels	0.199	0.801
I27 Other pulmonary heart diseases	0.199	0.801
I26 Pulmonary embolism	0.199	0.801
I52 Other heart disorders in diseases classified elsewhere	0.199	0.801
I51 Complications and ill-defined descriptions of heart disease	0.199	0.801
I50 Heart failure	0.199	0.801
I49 Other cardiac arrhythmias	0.199	0.801
I48 Atrial fibrillation and flutter	0.199	0.801
I47 Paroxysmal tachycardia	0.199	0.801
I46 Cardiac arrest	0.199	0.801
I45 Other conduction disorders	0.199	0.801
I44 Atrioventricular and left bundle-branch block	0.199	0.801
I43 Cardiomyopathy in diseases classified elsewhere	0.199	0.801
I42 Cardiomyopathy	0.199	0.801
I41 Myocarditis in diseases classified elsewhere	0.199	0.801
I40 Acute myocarditis	0.199	0.801
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.199	0.801
I37 Pulmonary valve disorders	0.199	0.801
I36 Nonrheumatic tricuspid valve disorders	0.199	0.801
I35 Nonrheumatic aortic valve disorders	0.199	0.801
I34 Nonrheumatic mitral valve disorders	0.199	0.801
I33 Acute and subacute endocarditis	0.199	0.801
I32 Pericarditis in diseases classified elsewhere	0.199	0.801
I31 Other diseases of pericardium	0.199	0.801
I30 Acute pericarditis	0.199	0.801
I38 Endocarditis, valve unspecified	0.199	0.801
I69 Sequelae of cerebrovascular disease	0.199	0.801
I68 Cerebrovascular disorders in diseases classified elsewhere	0.199	0.801
I67 Other cerebrovascular diseases	0.199	0.801
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.199	0.801
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.199	0.801
I63 Cerebral infarction	0.199	0.801
I62 Other nontraumatic intracranial haemorrhage	0.199	0.801
I61 Intracerebral haemorrhage	0.199	0.801
I60 Subarachnoid haemorrhage	0.199	0.801
I64 Stroke, not specified as haemorrhage or infarction	0.199	0.801
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.199	0.801
I78 Diseases of capillaries	0.199	0.801
I77 Other disorders of arteries and arterioles	0.199	0.801
I74 Arterial embolism and thrombosis	0.199	0.801
I73 Other peripheral vascular diseases	0.199	0.801
I72 Other aneurysm	0.199	0.801
I71 Aortic aneurysm and dissection	0.199	0.801
I70 Atherosclerosis	0.199	0.801
I98 Other disorders of circulatory system in diseases classified elsewhere	0.199	0.801
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.199	0.801
I95 Hypotension	0.199	0.801
I99 Other and unspecified disorders of circulatory system	0.199	0.801
I25.1 Atherosclerotic heart disease	0.198	0.801
K29.7 Gastritis, unspecified	0.198	0.802
K64 Haemorrhoids and perianal venous thrombosis	0.196	0.804
K61 Abscess of anal and rectal regions	0.196	0.804
K60 Fissure and fistula of anal and rectal regions	0.196	0.804
K58 Irritable bowel syndrome	0.196	0.804
K56 Paralytic ileus and intestinal obstruction without hernia	0.196	0.804
K55 Vascular disorders of intestine	0.196	0.804
G50-G59 Nerve, nerve root and plexus disorders	0.196	0.804
Z76 Persons encountering health services in other circumstances	0.196	0.804
Z75 Problems related to medical facilities and other health care	0.196	0.804
Z74 Problems related to care-provider dependency	0.196	0.804
Z73 Problems related to life-management difficulty	0.196	0.804
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.196	0.804
Z70 Counselling related to sexual attitude, behaviour and orientation	0.196	0.804
K51 Ulcerative colitis	0.195	0.805
K50 Crohn's disease [regional enteritis]	0.195	0.805
H25-H28 Disorders of lens	0.195	0.805
Z51 Other medical care	0.193	0.806
N20 Calculus of kidney and ureter	0.193	0.807
Z96.9 Presence of functional implant, unspecified	0.193	0.807
Z96.8 Presence of other specified functional implants	0.193	0.807
Z96.7 Presence of other bone and tendon implants	0.193	0.807
Z96.5 Presence of tooth-root and mandibular implants	0.193	0.807
Z96.4 Presence of endocrine implants	0.193	0.807
Z96.3 Presence of artificial larynx	0.193	0.807
Z96.2 Presence of otological and audiological implants	0.193	0.807
Z96.0 Presence of urogenital implants	0.193	0.807
Z13 Special screening examination for other diseases and disorders	0.192	0.808
Z12 Special screening examination for neoplasms	0.192	0.808
Z11 Special screening examination for infectious and parasitic diseases	0.192	0.808
Z10 Routine general health check-up of defined subpopulation	0.192	0.808
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.192	0.808
Z08 Follow-up examination after treatment for malignant neoplasm	0.192	0.808
Z04 Examination and observation for other reasons	0.192	0.808
Z03 Medical observation and evaluation for suspected diseases and conditions	0.192	0.808

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations