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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17081231
log Bayes Factor = 1.56724
Chromosome 13   position 66,967,622  (GRCh37) Explore rs17081231 on Ensembl!
Variant rs17081231 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.972 0.028 0.000
# Top node
0.970 0.030 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.957 0.043 0.000
M20-M25 Other joint disorders
0.954 0.046 0.000
Chapter VI Diseases of the nervous system
0.951 0.049 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.945 0.055 0.000
M45-M49 Spondylopathies
0.940 0.060 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.939 0.061 0.000
M23 Internal derangement of knee
0.938 0.062 0.000
Chapter XX External causes of morbidity and mortality
0.930 0.070 0.000
G56 Mononeuropathies of upper limb
0.921 0.079 0.000
R30-R39 Symptoms and signs involving the urinary system
0.919 0.081 0.000
G56.0 Carpal tunnel syndrome
0.901 0.099 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.892 0.108 0.000
M65-M68 Disorders of synovium and tendon
0.888 0.112 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.879 0.121 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.875 0.125 0.000
M23.3 Other meniscus derangements
0.871 0.129 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.866 0.134 0.000
M47 Spondylosis
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.862 0.138 0.000
S80-S89 Injuries to the knee and lower leg
0.861 0.139 0.000
R32 Unspecified urinary incontinence
0.853 0.147 0.000
Chapter IX Diseases of the circulatory system
0.842 0.158 0.000
R00 Abnormalities of heart beat
0.824 0.176 0.000
M50-M54 Other dorsopathies
0.821 0.179 0.000
M48 Other spondylopathies
0.821 0.179 0.000
M31 Other necrotising vasculopathies
0.819 0.181 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.818 0.182 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.815 0.185 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.813 0.187 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
R39 Other symptoms and signs involving the urinary system
0.806 0.194 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.804 0.196 0.000
M80-M85 Disorders of bone density and structure
0.804 0.196 0.000
R07 Pain in throat and chest
0.800 0.200 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.799 0.201 0.000
R00.1 Bradycardia, unspecified
0.796 0.204 0.000
S90-S99 Injuries to the ankle and foot
0.794 0.206 0.000
M65 Synovitis and tenosynovitis
0.793 0.207 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.787 0.213 0.000
M86-M90 Other osteopathies
0.787 0.213 0.000
M91-M94 Chondropathies
0.783 0.217 0.000
W00-W19 Falls
0.783 0.217 0.000
R79 Other abnormal findings of blood chemistry
0.783 0.217 0.000
G50 Disorders of trigeminal nerve
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.777 0.223 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.776 0.224 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.773 0.227 0.000
Chapter I Certain infectious and parasitic diseases
0.770 0.230 0.000
S82 Fracture of lower leg, including ankle
0.769 0.231 0.000
S40-S49 Injuries to the shoulder and upper arm
0.766 0.234 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.765 0.235 0.000
G51 Facial nerve disorders
0.764 0.236 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.763 0.237 0.000
T91 Sequelae of injuries of neck and trunk
0.761 0.239 0.000
M46 Other inflammatory spondylopathies
0.761 0.239 0.000
R07.3 Other chest pain
0.759 0.241 0.000
Chapter II Neoplasms
0.756 0.244 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.755 0.245 0.000
S81 Open wound of lower leg
0.752 0.248 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.751 0.249 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.750 0.250 0.000
A30-A49 Other bacterial diseases
0.749 0.251 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.748 0.252 0.000
R42 Dizziness and giddiness
0.746 0.254 0.000
Chapter XXII Codes for special purposes
0.745 0.255 0.000
M47.9 Spondylosis, unspecified
0.743 0.257 0.000
M24 Other specific joint derangements
0.742 0.258 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.742 0.258 0.000
T92 Sequelae of injuries of upper limb
0.742 0.258 0.000
R35 Polyuria
0.738 0.262 0.000
Chapter XI Diseases of the digestive system
0.737 0.263 0.000
M48.0 Spinal stenosis
0.735 0.265 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.734 0.266 0.000
R33 Retention of urine
0.730 0.270 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.727 0.273 0.000
K50-K52 Noninfective enteritis and colitis
0.727 0.273 0.000
M40-M43 Deforming dorsopathies
0.727 0.273 0.000
M31.6 Other giant cell arteritis
0.722 0.278 0.000
M21 Other acquired deformities of limbs
0.722 0.278 0.000
S00 Superficial injury of head
0.721 0.279 0.000
A41 Other septicaemia
0.721 0.279 0.000
R07.2 Precordial pain
0.721 0.279 0.000
M23.5 Chronic instability of knee
0.720 0.280 0.000
S50-S59 Injuries to the elbow and forearm
0.719 0.281 0.000
G54 Nerve root and plexus disorders
0.719 0.281 0.000
S10-S19 Injuries to the neck
0.718 0.282 0.000
K65-K67 Diseases of peritoneum
0.718 0.282 0.000
M47.2 Other spondylosis with radiculopathy
0.717 0.283 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
G57 Mononeuropathies of lower limb
0.714 0.286 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.714 0.286 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.713 0.287 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.713 0.287 0.000
M84 Disorders of continuity of bone
0.713 0.287 0.000
M22 Disorders of patella
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
R30 Pain associated with micturition
0.712 0.288 0.000
K52 Other non-infective gastro-enteritis and colitis
0.711 0.289 0.000
Y52 Agents primarily affecting the cardiovascular system
0.709 0.291 0.000
R34 Anuria and oliguria
0.708 0.292 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.708 0.292 0.000
R09.1 Pleurisy
0.707 0.293 0.000
G56.2 Lesion of ulnar nerve
0.706 0.294 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
M65.3 Trigger finger
0.703 0.297 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.702 0.298 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.702 0.298 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.701 0.299 0.000
G90-G99 Other disorders of the nervous system
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.697 0.303 0.000
K66 Other disorders of peritoneum
0.697 0.303 0.000
M60-M63 Disorders of muscles
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.697 0.303 0.000
M35 Other systemic involvement of connective tissue
0.696 0.304 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.695 0.304 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.695 0.305 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.695 0.305 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.694 0.306 0.000
I80 Phlebitis and thrombophlebitis
0.694 0.306 0.000
M67 Other disorders of synovium and tendon
0.693 0.307 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.693 0.307 0.000
S05 Injury of eye and orbit
0.690 0.310 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
R00.2 Palpitations
0.689 0.311 0.000
T66-T78 Other and unspecified effects of external causes
0.688 0.312 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.688 0.312 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.688 0.312 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.688 0.312 0.000
T33-T35 Frostbite
0.686 0.313 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.686 0.313 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.686 0.313 0.000
T00-T07 Injuries involving multiple body regions
0.686 0.313 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.685 0.315 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.684 0.316 0.000
M33 Dermatopolymyositis
0.684 0.316 0.000
M32 Systemic lupus erythematosus
0.684 0.316 0.000
M30 Polyarteritis nodosa and related conditions
0.684 0.316 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.684 0.316 0.000
I20-I25 Ischaemic heart diseases
0.684 0.316 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.683 0.317 0.000
K66.0 Peritoneal adhesions
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.682 0.318 0.000
I30-I52 Other forms of heart disease
0.682 0.318 0.000
M54 Dorsalgia
0.681 0.319 0.000
M66 Spontaneous rupture of synovium and tendon
0.681 0.319 0.000
R76 Other abnormal immunological findings in serum
0.681 0.319 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.678 0.322 0.000
G58 Other mononeuropathies
0.677 0.323 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.677 0.323 0.000
G52 Disorders of other cranial nerves
0.677 0.323 0.000
S00.8 Superficial injury of other parts of head
0.677 0.323 0.000
I83 Varicose veins of lower extremities
0.676 0.324 0.000
A41.9 Septicaemia, unspecified
0.675 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.325 0.000
M49 Spondylopathies in diseases classified elsewhere
0.674 0.326 0.000
M45 Ankylosing spondylitis
0.674 0.326 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.673 0.326 0.000
M51 Other intervertebral disk disorders
0.673 0.327 0.000
M23.9 Internal derangement of knee, unspecified
0.673 0.327 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.673 0.327 0.000
M23.1 Discoid meniscus (congenital)
0.673 0.327 0.000
M23.0 Cystic meniscus
0.673 0.327 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.672 0.328 0.000
S82.0 Fracture of patella
0.669 0.331 0.000
M23.4 Loose body in knee
0.667 0.333 0.000
M47.1 Other spondylosis with myelopathy
0.667 0.333 0.000
T93 Sequelae of injuries of lower limb
0.667 0.333 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.667 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.667 0.333 0.000
Y10-Y34 Event of undetermined intent
0.667 0.333 0.000
Y00-Y09 Assault
0.667 0.333 0.000
X85-X99 Assault
0.667 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
X30-X39 Exposure to forces of nature
0.667 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
X10-X19 Contact with heat and hot substances
0.667 0.333 0.000
X00-X09 Exposure to smoke, fire and flames
0.667 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.667 0.333 0.000
W75-W84 Other accidental threats to breathing
0.667 0.333 0.000
W65-W74 Accidental drowning and submersion
0.667 0.333 0.000
V98-V99 Other and unspecified transport accidents
0.667 0.333 0.000
V95-V97 Air and space transport accidents
0.667 0.333 0.000
V90-V94 Water transport accidents
0.667 0.333 0.000
V80-V89 Other land transport accidents
0.667 0.333 0.000
V70-V79 Bus occupant injured in transport accident
0.667 0.333 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.667 0.333 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.667 0.333 0.000
V40-V49 Car occupant injured in transport accident
0.667 0.333 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.667 0.333 0.000
V01-V09 Pedestrian injured in transport accident
0.667 0.333 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.665 0.335 0.000
V10-V19 Pedal cyclist injured in transport accident
0.663 0.337 0.000
Chapter V Mental and behavioural disorders
0.662 0.338 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.660 0.339 0.000
G56.8 Other mononeuropathies of upper limb
0.660 0.339 0.000
G56.4 Causalgia
0.660 0.339 0.000
G56.3 Lesion of radial nerve
0.660 0.339 0.000
G56.1 Other lesions of median nerve
0.660 0.339 0.000
G50.0 Trigeminal neuralgia
0.660 0.340 0.000
R74 Abnormal serum enzyme levels
0.659 0.341 0.000
R36 Urethral discharge
0.659 0.341 0.000
Y43 Primarily systemic agents
0.658 0.342 0.000
T79-T79 Certain early complications of trauma
0.657 0.343 0.000
I25 Chronic ischaemic heart disease
0.657 0.343 0.000
S20-S29 Injuries to the thorax
0.654 0.346 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.654 0.346 0.000
D70 Agranulocytosis
0.652 0.348 0.000
S92 Fracture of foot, except ankle
0.652 0.348 0.000
Y40 Systemic antibiotics
0.651 0.349 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.651 0.349 0.000
S60-S69 Injuries to the wrist and hand
0.651 0.349 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.650 0.350 0.000
K70-K77 Diseases of liver
0.649 0.351 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.646 0.353 0.000
G12 Spinal muscular atrophy and related syndromes
0.646 0.354 0.000
I73 Other peripheral vascular diseases
0.646 0.354 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.645 0.355 0.000
S81.9 Open wound of lower leg, part unspecified
0.645 0.355 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.644 0.356 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.644 0.356 0.000
R79.0 Abnormal level of blood mineral
0.643 0.356 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.643 0.357 0.000
M25 Other joint disorders, not elsewhere classified
0.643 0.357 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.642 0.358 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.641 0.359 0.000
I44 Atrioventricular and left bundle-branch block
0.640 0.360 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.639 0.360 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.639 0.360 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.639 0.360 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.639 0.360 0.000
M65.34 Trigger finger-Hand
0.639 0.361 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.636 0.364 0.000
S70-S79 Injuries to the hip and thigh
0.636 0.364 0.000
G51.0 Bell's palsy
0.635 0.365 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.635 0.365 0.000
M47.8 Other spondylosis
0.634 0.366 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.633 0.367 0.000
Y44 Agents primarily affecting blood constituents
0.633 0.367 0.000
C15-C26 Malignant neoplasms of digestive organs
0.632 0.368 0.000
D00-D09 In situ neoplasms
0.632 0.368 0.000
M23.8 Other internal derangements of knee
0.631 0.369 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.631 0.369 0.000
I73.0 Raynaud's syndrome
0.630 0.370 0.000
T98 Sequelae of other and unspecified effects of external causes
0.630 0.370 0.000
T95 Sequelae of burns, corrosions and frostbite
0.630 0.370 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.630 0.370 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.630 0.370 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.630 0.370 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.630 0.370 0.000
M94 Other disorders of cartilage
0.630 0.370 0.000
A49 Bacterial infection of unspecified site
0.630 0.370 0.000
M48.06 Spinal stenosis (Lumbar region)
0.630 0.370 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.628 0.372 0.000
I82 Other venous embolism and thrombosis
0.628 0.372 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.627 0.372 0.000
R77 Other abnormalities of plasma proteins
0.627 0.372 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.627 0.372 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.627 0.372 0.000
R71 Abnormality of red blood cells
0.627 0.372 0.000
X60-X84 Intentional self-harm
0.627 0.373 0.000
T90 Sequelae of injuries of head
0.627 0.373 0.000
R09.2 Respiratory arrest
0.625 0.375 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.625 0.375 0.000
W06 Fall involving bed
0.625 0.375 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.625 0.375 0.000
M23.37 Other meniscus derangements-Capsular lig
0.624 0.376 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.624 0.376 0.000
S82.6 Fracture of lateral malleolus
0.623 0.377 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.623 0.377 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.619 0.381 0.000
S82.4 Fracture of fibula alone
0.619 0.381 0.000
M90 Osteopathies in diseases classified elsewhere
0.619 0.381 0.000
Y59 Other and unspecified vaccines and biological substances
0.618 0.382 0.000
Y58 Bacterial vaccines
0.618 0.382 0.000
Y57 Other and unspecified drugs and medicaments
0.618 0.382 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.618 0.382 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.618 0.382 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.618 0.382 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.618 0.382 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.618 0.382 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.618 0.382 0.000
Y48 Anaesthetics and therapeutic gases
0.618 0.382 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.618 0.382 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.618 0.382 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.618 0.382 0.000
W10 Fall on and from stairs and steps
0.618 0.382 0.000
S89 Other and unspecified injuries of lower leg
0.618 0.382 0.000
S88 Traumatic amputation of lower leg
0.618 0.382 0.000
S87 Crushing injury of lower leg
0.618 0.382 0.000
S86 Injury of muscle and tendon at lower leg level
0.618 0.382 0.000
S85 Injury of blood vessels at lower leg level
0.618 0.382 0.000
S84 Injury of nerves at lower leg level
0.618 0.382 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.617 0.383 0.000
I31 Other diseases of pericardium
0.616 0.384 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.614 0.386 0.000
M89 Other disorders of bone
0.613 0.387 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.613 0.387 0.000
T18 Foreign body in alimentary tract
0.612 0.388 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.611 0.389 0.000
D60-D64 Aplastic and other anaemias
0.610 0.389 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.610 0.390 0.000
S90 Superficial injury of ankle and foot
0.609 0.391 0.000
C64-C68 Malignant neoplasms of urinary tract
0.608 0.392 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.607 0.393 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.606 0.393 0.000
W13 Fall from, out of or through building or structure
0.606 0.394 0.000
I35 Nonrheumatic aortic valve disorders
0.605 0.395 0.000
I00-I02 Acute rheumatic fever
0.604 0.396 0.000
T17 Foreign body in respiratory tract
0.604 0.396 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.603 0.397 0.000
S05.1 Contusion of eyeball and orbital tissues
0.603 0.397 0.000
T91.3 Sequelae of injury of spinal cord
0.603 0.397 0.000
I87 Other disorders of veins
0.603 0.397 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.602 0.398 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.600 0.400 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.599 0.401 0.000
I81 Portal vein thrombosis
0.599 0.401 0.000
S82.00 Fracture of patella (closed)
0.598 0.402 0.000
K51 Ulcerative colitis
0.597 0.403 0.000
G59.0 Diabetic mononeuropathy
0.597 0.403 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.597 0.403 0.000
I44.7 Left bundle-branch block, unspecified
0.595 0.405 0.000
R01 Cardiac murmurs and other cardiac sounds
0.594 0.405 0.000
G30-G32 Other degenerative diseases of the nervous system
0.592 0.408 0.000
D75 Other diseases of blood and blood-forming organs
0.591 0.409 0.000
M35.0 Sicca syndrome [Sjogren]
0.591 0.409 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.589 0.411 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.589 0.411 0.000
M53 Other dorsopathies, not elsewhere classified
0.588 0.411 0.000
M48.9 Spondylopathy, unspecified
0.588 0.411 0.000
M48.8 Other specified spondylopathies
0.588 0.411 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.588 0.411 0.000
M48.4 Fatigue fracture of vertebra
0.588 0.411 0.000
M48.3 Traumatic spondylopathy
0.588 0.411 0.000
M48.2 Kissing spine
0.588 0.411 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.588 0.411 0.000
M93 Other osteochondropathies
0.588 0.412 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.588 0.412 0.000
S06 Intracranial injury
0.588 0.412 0.000
D37.5 Rectum
0.588 0.412 0.000
M31.9 Necrotising vasculopathy, unspecified
0.587 0.413 0.000
M31.8 Other specified necrotising vasculopathies
0.587 0.413 0.000
M31.7 Microscopic polyangiitis
0.587 0.413 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.587 0.413 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.587 0.413 0.000
M31.3 Wegener's granulomatosis
0.587 0.413 0.000
M31.2 Lethal midline granuloma
0.587 0.413 0.000
M31.1 Thrombotic microangiopathy
0.587 0.413 0.000
M31.0 Hypersensitivity angiitis
0.587 0.413 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.587 0.413 0.000
D45 Polycythaemia vera
0.586 0.414 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.585 0.415 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.584 0.416 0.000
K65 Peritonitis
0.584 0.416 0.000
R46 Symptoms and signs involving appearance and behaviour
0.584 0.416 0.000
R45 Symptoms and signs involving emotional state
0.584 0.416 0.000
R43 Disturbances of smell and taste
0.584 0.416 0.000
K50 Crohn's disease [regional enteritis]
0.583 0.417 0.000
G62 Other polyneuropathies
0.583 0.417 0.000
R23 Other skin changes
0.583 0.417 0.000
S09 Other and unspecified injuries of head
0.582 0.418 0.000
S08 Traumatic amputation of part of head
0.582 0.418 0.000
S07 Crushing injury of head
0.582 0.418 0.000
S04 Injury of cranial nerves
0.582 0.418 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.582 0.418 0.000
M24.1 Other articular cartilage disorders
0.582 0.418 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.581 0.419 0.000
R20 Disturbances of skin sensation
0.580 0.420 0.000
M05-M14 Inflammatory polyarthropathies
0.580 0.420 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.579 0.420 0.000
T92.1 Sequelae of fracture of arm
0.579 0.420 0.000
D37.4 Colon
0.579 0.421 0.000
R87 Abnormal findings in specimens from female genital organs
0.578 0.422 0.000
R39.2 Extrarenal uraemia
0.578 0.422 0.000
R39.0 Extravasation of urine
0.578 0.422 0.000
M85 Other disorders of bone density and structure
0.578 0.422 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.577 0.423 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.577 0.423 0.000
D55-D59 Haemolytic anaemias
0.576 0.423 0.000
M83 Adult osteomalacia
0.576 0.423 0.000
M82 Osteoporosis in diseases classified elsewhere
0.576 0.423 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.576 0.424 0.000
S81.0 Open wound of knee
0.576 0.424 0.000
M80 Osteoporosis with pathological fracture
0.574 0.425 0.000
R09.3 Abnormal sputum
0.573 0.427 0.000
R09.0 Asphyxia
0.573 0.427 0.000
S82.1 Fracture of upper end of tibia
0.573 0.427 0.000
K52.1 Toxic gastro-enteritis and colitis
0.571 0.428 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.571 0.429 0.000
M87 Osteonecrosis
0.571 0.429 0.000
G82 Paraplegia and tetraplegia
0.571 0.429 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.570 0.430 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.570 0.430 0.000
I25.2 Old myocardial infarction
0.570 0.430 0.000
S99 Other and unspecified injuries of ankle and foot
0.569 0.430 0.000
S98 Traumatic amputation of ankle and foot
0.569 0.430 0.000
S97 Crushing injury of ankle and foot
0.569 0.430 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.569 0.430 0.000
S95 Injury of blood vessels at ankle and foot level
0.569 0.430 0.000
S94 Injury of nerves at ankle and foot level
0.569 0.430 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.569 0.430 0.000
S91 Open wound of ankle and foot
0.569 0.430 0.000
C15 Malignant neoplasm of oesophagus
0.569 0.431 0.000
M65.8 Other synovitis and tenosynovitis
0.568 0.431 0.000
M65.2 Calcific tendinitis
0.568 0.431 0.000
M65.1 Other infective (teno)synovitis
0.568 0.431 0.000
M65.0 Abscess of tendon sheath
0.568 0.431 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.568 0.432 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.567 0.433 0.000
I95 Hypotension
0.567 0.433 0.000
G20-G26 Extrapyramidal and movement disorders
0.566 0.434 0.000
R06 Abnormalities of breathing
0.566 0.434 0.000
M54.4 Lumbago with sciatica
0.566 0.434 0.000
R07.0 Pain in throat
0.565 0.435 0.000
M99 Biomechanical lesions, not elsewhere classified
0.564 0.436 0.000
M86 Osteomyelitis
0.564 0.436 0.000
S81.8 Open wound of other parts of lower leg
0.564 0.436 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.564 0.436 0.000
M54.3 Sciatica
0.564 0.436 0.000
R30.0 Dysuria
0.563 0.437 0.000
I31.3 Pericardial effusion (noninflammatory)
0.563 0.437 0.000
M92 Other juvenile osteochondrosis
0.562 0.438 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.562 0.438 0.000
W18 Other fall on same level
0.562 0.438 0.000
W17 Other fall from one level to another
0.562 0.438 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.562 0.438 0.000
W15 Fall from cliff
0.562 0.438 0.000
W14 Fall from tree
0.562 0.438 0.000
W12 Fall on and from scaffolding
0.562 0.438 0.000
W11 Fall on and from ladder
0.562 0.438 0.000
W09 Fall involving playground equipment
0.562 0.438 0.000
W08 Fall involving other furniture
0.562 0.438 0.000
W05 Fall involving wheelchair
0.562 0.438 0.000
W04 Fall while being carried or supported by other persons
0.562 0.438 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.562 0.438 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.562 0.438 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.562 0.438 0.000
W00 Fall on same level involving ice and snow
0.562 0.438 0.000
S00.3 Superficial injury of nose
0.562 0.438 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.561 0.438 0.000
I33 Acute and subacute endocarditis
0.560 0.440 0.000
W07 Fall involving chair
0.559 0.441 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.558 0.441 0.000
G50.8 Other disorders of trigeminal nerve
0.558 0.441 0.000
G50.1 Atypical facial pain
0.558 0.441 0.000
S42 Fracture of shoulder and upper arm
0.558 0.442 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.557 0.442 0.000
T19 Foreign body in genito-urinary tract
0.557 0.443 0.000
T15 Foreign body on external eye
0.557 0.443 0.000
T16 Foreign body in ear
0.557 0.443 0.000
I88 Nonspecific lymphadenitis
0.557 0.443 0.000
W55 Bitten or struck by other mammals
0.556 0.444 0.000
A80-A89 Viral infections of the central nervous system
0.556 0.444 0.000
M43 Other deforming dorsopathies
0.555 0.445 0.000
S82.2 Fracture of shaft of tibia
0.555 0.445 0.000
M88 Paget's disease of bone [osteitis deformans]
0.555 0.445 0.000
G12.2 Motor neuron disease
0.555 0.445 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.554 0.445 0.000
G11 Hereditary ataxia
0.554 0.445 0.000
G14 Postpolio syndrome
0.554 0.445 0.000
G10 Huntington's disease
0.554 0.445 0.000
Y83.3 Surgical operation with formation of external stoma
0.554 0.446 0.000
D46 Myelodysplastic syndromes
0.554 0.446 0.000
D37.6 Liver, gallbladder and bile ducts
0.553 0.447 0.000
B99-B99 Other infectious diseases
0.552 0.448 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.552 0.448 0.000
B65-B83 Helminthiases
0.552 0.448 0.000
B50-B64 Protozoal diseases
0.552 0.448 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.552 0.448 0.000
B15-B19 Viral hepatitis
0.552 0.448 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.552 0.448 0.000
A75-A79 Rickettsioses
0.552 0.448 0.000
A70-A74 Other diseases caused by chlamydiae
0.552 0.448 0.000
A65-A69 Other spirochaetal diseases
0.552 0.448 0.000
A20-A28 Certain zoonotic bacterial diseases
0.552 0.448 0.000
A15-A19 Tuberculosis
0.552 0.448 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.552 0.448 0.000
S82.9 Fracture of lower leg, part unspecified
0.552 0.448 0.000
S82.7 Multiple fractures of lower leg
0.552 0.448 0.000
M22.2 Patellofemoral disorders
0.552 0.448 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.551 0.448 0.000
D72 Other disorders of white blood cells
0.551 0.448 0.000
I86 Varicose veins of other sites
0.551 0.449 0.000
I85 Oesophageal varices
0.551 0.449 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.551 0.449 0.000
R07.1 Chest pain on breathing
0.551 0.449 0.000
I22 Subsequent myocardial infarction
0.551 0.449 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.549 0.451 0.000
S48 Traumatic amputation of shoulder and upper arm
0.549 0.451 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.549 0.451 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.549 0.451 0.000
S44 Injury of nerves at shoulder and upper arm level
0.549 0.451 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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