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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17437544
log Bayes Factor = 16.9402
Chromosome 7   position 27,231,189  (GRCh37) Explore rs17437544 on Ensembl!
Variant rs17437544 is part of Cluster X0029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
M50-M54 Other dorsopathies
0.992 0.008 0.000
E70-E90 Metabolic disorders
0.992 0.008 0.000
Chapter II Neoplasms
0.990 0.010 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.982 0.018 0.000
J40-J47 Chronic lower respiratory diseases
0.982 0.018 0.000
E86 Volume depletion
0.981 0.019 0.000
Chapter XX External causes of morbidity and mortality
0.978 0.022 0.000
M51 Other intervertebral disk disorders
0.976 0.024 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.972 0.028 0.000
Chapter I Certain infectious and parasitic diseases
0.972 0.028 0.000
C79 Secondary malignant neoplasm of other sites
0.971 0.029 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.968 0.032 0.000
Chapter XI Diseases of the digestive system
0.967 0.033 0.000
K55-K64 Other diseases of intestines
0.966 0.034 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.966 0.034 0.000
M51.2 Other specified intervertebral disk displacement
0.965 0.035 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.965 0.035 0.000
A30-A49 Other bacterial diseases
0.965 0.035 0.000
J47 Bronchiectasis
0.964 0.036 0.000
S01 Open wound of head
0.964 0.036 0.000
K57 Diverticular disease of intestine
0.964 0.036 0.000
Chapter VII Diseases of the eye and adnexa
0.963 0.037 0.000
Chapter VI Diseases of the nervous system
0.963 0.037 0.000
A41 Other septicaemia
0.959 0.041 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.958 0.042 0.000
A41.9 Septicaemia, unspecified
0.955 0.045 0.000
Chapter IX Diseases of the circulatory system
0.951 0.049 0.000
R94 Abnormal results of function studies
0.938 0.062 0.000
M20-M25 Other joint disorders
0.936 0.064 0.000
J20-J22 Other acute lower respiratory infections
0.936 0.064 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.935 0.065 0.000
S01.8 Open wound of other parts of head
0.926 0.074 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.922 0.078 0.000
M54 Dorsalgia
0.920 0.080 0.000
J44 Other chronic obstructive pulmonary disease
0.914 0.086 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.913 0.087 0.000
R94.5 Abnormal results of liver function studies
0.912 0.088 0.000
K58 Irritable bowel syndrome
0.909 0.091 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.907 0.093 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.906 0.094 0.000
R25 Abnormal involuntary movements
0.893 0.107 0.000
J22 Unspecified acute lower respiratory infection
0.891 0.109 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.890 0.110 0.000
I60-I69 Cerebrovascular diseases
0.890 0.110 0.000
E20-E35 Disorders of other endocrine glands
0.889 0.111 0.000
R30-R39 Symptoms and signs involving the urinary system
0.888 0.112 0.000
R47-R49 Symptoms and signs involving speech and voice
0.887 0.113 0.000
I30-I52 Other forms of heart disease
0.887 0.113 0.000
M25 Other joint disorders, not elsewhere classified
0.886 0.114 0.000
I10-I15 Hypertensive diseases
0.886 0.114 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.884 0.116 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.877 0.123 0.000
J95-J99 Other diseases of the respiratory system
0.877 0.123 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.877 0.123 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.877 0.123 0.000
S09 Other and unspecified injuries of head
0.876 0.124 0.000
E87.6 Hypokalaemia
0.871 0.129 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.871 0.129 0.000
C64-C68 Malignant neoplasms of urinary tract
0.869 0.131 0.000
E87.2 Acidosis
0.866 0.134 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.866 0.134 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.864 0.136 0.000
D00-D09 In situ neoplasms
0.861 0.139 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.860 0.140 0.000
M45-M49 Spondylopathies
0.859 0.141 0.000
S02 Fracture of skull and facial bones
0.856 0.144 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.855 0.145 0.000
J30-J39 Other diseases of upper respiratory tract
0.855 0.145 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.848 0.152 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.847 0.153 0.000
R39 Other symptoms and signs involving the urinary system
0.847 0.153 0.000
M25.5 Pain in joint
0.847 0.153 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.844 0.156 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.842 0.158 0.000
O36 Maternal care for other known or suspected foetal problems
0.841 0.159 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.838 0.162 0.000
S20-S29 Injuries to the thorax
0.835 0.164 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.834 0.166 0.000
S06 Intracranial injury
0.834 0.166 0.000
R06 Abnormalities of breathing
0.831 0.169 0.000
R47 Speech disturbances, not elsewhere classified
0.830 0.170 0.000
I10 Essential (primary) hypertension
0.830 0.170 0.000
R35 Polyuria
0.828 0.172 0.000
R39.1 Other difficulties with micturition
0.821 0.179 0.000
R06.0 Dyspnoea
0.818 0.182 0.000
S50-S59 Injuries to the elbow and forearm
0.818 0.182 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.816 0.184 0.000
M25.51 Pain in joint (Shoulder region)
0.810 0.190 0.000
M40-M43 Deforming dorsopathies
0.809 0.191 0.000
O00-O08 Pregnancy with abortive outcome
0.809 0.191 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.807 0.193 0.000
M54.3 Sciatica
0.807 0.193 0.000
R25.1 Tremor, unspecified
0.807 0.193 0.000
E50-E64 Other nutritional deficiencies
0.804 0.196 0.000
J60-J70 Lung diseases due to external agents
0.801 0.198 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.801 0.199 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.800 0.200 0.000
Chapter V Mental and behavioural disorders
0.797 0.203 0.000
R29.6 Tendency to fall, not elsewhere classified
0.796 0.204 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.796 0.204 0.000
G35 Multiple sclerosis
0.796 0.204 0.000
I45 Other conduction disorders
0.795 0.205 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.794 0.206 0.000
D70 Agranulocytosis
0.794 0.206 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.793 0.207 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.791 0.209 0.000
S05 Injury of eye and orbit
0.790 0.210 0.000
S09.9 Unspecified injury of head
0.790 0.210 0.000
H30-H36 Disorders of choroid and retina
0.790 0.210 0.000
Chapter XIV Diseases of the genitourinary system
0.787 0.213 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.786 0.214 0.000
M80-M85 Disorders of bone density and structure
0.784 0.216 0.000
K61 Abscess of anal and rectal regions
0.783 0.217 0.000
J33 Nasal polyp
0.782 0.218 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
E10-E14 Diabetes mellitus
0.781 0.219 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.779 0.221 0.000
R47.0 Dysphasia and aphasia
0.779 0.221 0.000
E65-E68 Obesity and other hyperalimentation
0.779 0.221 0.000
A41.8 Other specified septicaemia
0.776 0.224 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.775 0.225 0.000
M48 Other spondylopathies
0.774 0.226 0.000
M21 Other acquired deformities of limbs
0.774 0.226 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.772 0.228 0.000
N17-N19 Renal failure
0.772 0.228 0.000
K62 Other diseases of anus and rectum
0.771 0.229 0.000
W20-W49 Exposure to inanimate mechanical forces
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.768 0.232 0.000
E00-E07 Disorders of thyroid gland
0.768 0.232 0.000
D80-D89 Certain disorders involving the immune mechanism
0.767 0.232 0.000
M54.1 Radiculopathy
0.766 0.234 0.000
M24 Other specific joint derangements
0.765 0.235 0.000
S01.0 Open wound of scalp
0.764 0.236 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.763 0.237 0.000
H25-H28 Disorders of lens
0.763 0.237 0.000
I63 Cerebral infarction
0.763 0.237 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.763 0.237 0.000
M54.9 Dorsalgia, unspecified
0.763 0.237 0.000
V80-V89 Other land transport accidents
0.762 0.238 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.762 0.238 0.000
S01.5 Open wound of lip and oral cavity
0.760 0.240 0.000
C78.0 Secondary malignant neoplasm of lung
0.759 0.241 0.000
C67 Malignant neoplasm of bladder
0.756 0.244 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.756 0.244 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.755 0.245 0.000
C79.2 Secondary malignant neoplasm of skin
0.755 0.245 0.000
N18 Chronic renal failure
0.754 0.246 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.753 0.247 0.000
O60-O75 Complications of labour and delivery
0.752 0.248 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.751 0.249 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.750 0.250 0.000
R27 Other lack of coordination
0.750 0.250 0.000
M70-M79 Other soft tissue disorders
0.748 0.252 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.746 0.254 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.743 0.257 0.000
H55-H59 Other disorders of eye and adnexa
0.741 0.259 0.000
H10-H13 Disorders of conjunctiva
0.740 0.260 0.000
M23 Internal derangement of knee
0.740 0.260 0.000
H00 Hordeolum and chalazion
0.739 0.261 0.000
R94.3 Abnormal results of cardiovascular function studies
0.738 0.262 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.737 0.263 0.000
J33.9 Nasal polyp, unspecified
0.737 0.263 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
K35-K38 Diseases of appendix
0.736 0.264 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.735 0.265 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.734 0.266 0.000
H53-H54 Visual disturbances and blindness
0.733 0.267 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.732 0.268 0.000
A80-A89 Viral infections of the central nervous system
0.732 0.268 0.000
Y43 Primarily systemic agents
0.731 0.269 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.731 0.269 0.000
K62.8 Other specified diseases of anus and rectum
0.730 0.270 0.000
D06 Carcinoma in situ of cervix uteri
0.730 0.270 0.000
J30 Vasomotor and allergic rhinitis
0.729 0.271 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.728 0.271 0.000
E28 Ovarian dysfunction
0.728 0.272 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.728 0.272 0.000
R25.2 Cramp and spasm
0.727 0.273 0.000
J90-J94 Other diseases of pleura
0.727 0.273 0.000
Y84.8 Other medical procedures
0.727 0.273 0.000
K90-K93 Other diseases of the digestive system
0.726 0.274 0.000
N18.9 Chronic renal failure, unspecified
0.726 0.274 0.000
I69 Sequelae of cerebrovascular disease
0.725 0.274 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.724 0.276 0.000
M54.4 Lumbago with sciatica
0.723 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.722 0.278 0.000
A49 Bacterial infection of unspecified site
0.722 0.278 0.000
J46 Status asthmaticus
0.722 0.278 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.721 0.279 0.000
W00-W19 Falls
0.719 0.281 0.000
M86-M90 Other osteopathies
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.716 0.284 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.716 0.284 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.715 0.285 0.000
I46 Cardiac arrest
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
Y86 Sequelae of other accidents
0.714 0.286 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.713 0.287 0.000
M48.0 Spinal stenosis
0.713 0.287 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.713 0.287 0.000
M54.2 Cervicalgia
0.713 0.287 0.000
O02 Other abnormal products of conception
0.713 0.287 0.000
S80-S89 Injuries to the knee and lower leg
0.712 0.288 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.712 0.288 0.000
I44 Atrioventricular and left bundle-branch block
0.711 0.289 0.000
M53 Other dorsopathies, not elsewhere classified
0.711 0.289 0.000
E88 Other metabolic disorders
0.711 0.289 0.000
E85 Amyloidosis
0.711 0.289 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
E73 Lactose intolerance
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
O36.5 Maternal care for poor foetal growth
0.711 0.289 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.290 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.710 0.290 0.000
J98 Other respiratory disorders
0.709 0.291 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
Y57 Other and unspecified drugs and medicaments
0.707 0.293 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.707 0.293 0.000
S01.2 Open wound of nose
0.707 0.293 0.000
C80 Malignant neoplasm without specification of site
0.706 0.294 0.000
I45.1 Other and unspecified right bundle-branch block
0.706 0.294 0.000
G30-G32 Other degenerative diseases of the nervous system
0.705 0.295 0.000
E87.7 Fluid overload
0.705 0.295 0.000
T39.1 4-Aminophenol derivatives
0.705 0.295 0.000
G54 Nerve root and plexus disorders
0.704 0.295 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.704 0.296 0.000
R26 Abnormalities of gait and mobility
0.704 0.296 0.000
J41 Simple and mucopurulent chronic bronchitis
0.704 0.296 0.000
J42 Unspecified chronic bronchitis
0.704 0.296 0.000
S01.1 Open wound of eyelid and periocular area
0.704 0.296 0.000
S02.6 Fracture of mandible
0.703 0.297 0.000
J40 Bronchitis, not specified as acute or chronic
0.703 0.297 0.000
K65-K67 Diseases of peritoneum
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
W50-W64 Exposure to animate mechanical forces
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V40-V49 Car occupant injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
C60-C63 Malignant neoplasms of male genital organs
0.701 0.299 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.701 0.299 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.700 0.300 0.000
I11 Hypertensive heart disease
0.700 0.300 0.000
M51.3 Other specified intervertebral disk degeneration
0.700 0.300 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.700 0.300 0.000
M51.9 Intervertebral disk disorder, unspecified
0.700 0.300 0.000
M51.8 Other specified intervertebral disk disorders
0.700 0.300 0.000
M51.4 Schmorl's nodes
0.700 0.300 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.700 0.300 0.000
S06.5 Traumatic subdural haemorrhage
0.700 0.300 0.000
S40-S49 Injuries to the shoulder and upper arm
0.698 0.301 0.000
I67 Other cerebrovascular diseases
0.698 0.302 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.698 0.302 0.000
H35 Other retinal disorders
0.698 0.302 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.698 0.302 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.697 0.303 0.000
H02 Other disorders of eyelid
0.697 0.303 0.000
B99-B99 Other infectious diseases
0.697 0.303 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.697 0.303 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.697 0.303 0.000
B65-B83 Helminthiases
0.697 0.303 0.000
B50-B64 Protozoal diseases
0.697 0.303 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.697 0.303 0.000
B15-B19 Viral hepatitis
0.697 0.303 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.697 0.303 0.000
A75-A79 Rickettsioses
0.697 0.303 0.000
A70-A74 Other diseases caused by chlamydiae
0.697 0.303 0.000
A65-A69 Other spirochaetal diseases
0.697 0.303 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.697 0.303 0.000
A20-A28 Certain zoonotic bacterial diseases
0.697 0.303 0.000
A15-A19 Tuberculosis
0.697 0.303 0.000
C79.6 Secondary malignant neoplasm of ovary
0.696 0.304 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.696 0.304 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.696 0.304 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.696 0.304 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.696 0.304 0.000
M15-M19 Arthrosis
0.694 0.306 0.000
O85-O92 Complications predominantly related to the puerperium
0.694 0.306 0.000
G50 Disorders of trigeminal nerve
0.693 0.307 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.693 0.307 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.693 0.307 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.693 0.307 0.000
E87.4 Mixed disorder of acid-base balance
0.693 0.307 0.000
E87.3 Alkalosis
0.693 0.307 0.000
E87.0 Hyperosmolality and hypernatraemia
0.693 0.307 0.000
E87.5 Hyperkalaemia
0.692 0.308 0.000
X60-X84 Intentional self-harm
0.692 0.308 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.692 0.308 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.692 0.308 0.000
A48 Other bacterial diseases, not elsewhere classified
0.692 0.308 0.000
A44 Bartonellosis
0.692 0.308 0.000
A43 Nocardiosis
0.692 0.308 0.000
A42 Actinomycosis
0.692 0.308 0.000
A40 Streptococcal septicaemia
0.692 0.308 0.000
A39 Meningococcal infection
0.692 0.308 0.000
A37 Whooping cough
0.692 0.308 0.000
A36 Diphtheria
0.692 0.308 0.000
A32 Listeriosis
0.692 0.308 0.000
A31 Infection due to other mycobacteria
0.692 0.308 0.000
A30 Leprosy [Hansen's disease]
0.692 0.308 0.000
A46 Erysipelas
0.692 0.308 0.000
A38 Scarlet fever
0.692 0.308 0.000
A35 Other tetanus
0.692 0.308 0.000
A34 Obstetrical tetanus
0.692 0.308 0.000
A33 Tetanus neonatorum
0.692 0.308 0.000
S01.7 Multiple open wounds of head
0.691 0.309 0.000
S01.4 Open wound of cheek and temporomandibular area
0.691 0.309 0.000
S01.3 Open wound of ear
0.691 0.309 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.691 0.309 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.691 0.309 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.691 0.309 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.691 0.309 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.691 0.309 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.691 0.309 0.000
G70-G73 Diseases of myoneural junction and muscle
0.690 0.310 0.000
S00 Superficial injury of head
0.690 0.310 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.690 0.310 0.000
K55 Vascular disorders of intestine
0.690 0.310 0.000
H01 Other inflammation of eyelid
0.689 0.310 0.000
S02.4 Fracture of malar and maxillary bones
0.689 0.311 0.000
G37 Other demyelinating diseases of central nervous system
0.688 0.311 0.000
A41.4 Septicaemia due to anaerobes
0.688 0.312 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.688 0.312 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.688 0.312 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.688 0.312 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.688 0.312 0.000
M35 Other systemic involvement of connective tissue
0.688 0.312 0.000
S52 Fracture of forearm
0.687 0.313 0.000
D50-D53 Nutritional anaemias
0.686 0.314 0.000
S60-S69 Injuries to the wrist and hand
0.685 0.314 0.000
H52 Disorders of refraction and accommodation
0.684 0.316 0.000
M54.36 Sciatica (Lumbar region)
0.683 0.317 0.000
G58 Other mononeuropathies
0.682 0.318 0.000
I00-I02 Acute rheumatic fever
0.682 0.318 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.682 0.318 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.681 0.319 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.681 0.319 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.681 0.319 0.000
S20 Superficial injury of thorax
0.681 0.319 0.000
O42 Premature rupture of membranes
0.681 0.319 0.000
E14 Unspecified diabetes mellitus
0.680 0.320 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.680 0.320 0.000
I49 Other cardiac arrhythmias
0.679 0.321 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.679 0.321 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.679 0.321 0.000
I50 Heart failure
0.678 0.322 0.000
M25.7 Osteophyte
0.678 0.322 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.677 0.323 0.000
I05-I09 Chronic rheumatic heart diseases
0.677 0.323 0.000
V10-V19 Pedal cyclist injured in transport accident
0.675 0.325 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.675 0.325 0.000
R20 Disturbances of skin sensation
0.674 0.326 0.000
E22 Hyperfunction of pituitary gland
0.673 0.327 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.673 0.327 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.672 0.328 0.000
R94.7 Abnormal results of other endocrine function studies
0.672 0.328 0.000
R94.6 Abnormal results of thyroid function studies
0.672 0.328 0.000
R94.4 Abnormal results of kidney function studies
0.672 0.328 0.000
R94.2 Abnormal results of pulmonary function studies
0.672 0.328 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.672 0.328 0.000
R94.0 Abnormal results of function studies of central nervous system
0.672 0.328 0.000
O36.8 Maternal care for other specified foetal problems
0.671 0.329 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.671 0.329 0.000
M34 Systemic sclerosis
0.671 0.329 0.000
M33 Dermatopolymyositis
0.671 0.329 0.000
M32 Systemic lupus erythematosus
0.671 0.329 0.000
M31 Other necrotising vasculopathies
0.671 0.329 0.000
M30 Polyarteritis nodosa and related conditions
0.671 0.329 0.000
J21 Acute bronchiolitis
0.671 0.329 0.000
J20 Acute bronchitis
0.671 0.329 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.670 0.329 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.329 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.670 0.329 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.670 0.329 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.670 0.329 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.670 0.329 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.670 0.329 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.670 0.329 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.670 0.329 0.000
T36 Poisoning by systemic antibiotics
0.670 0.329 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.670 0.329 0.000
N99-N99 Other disorders of the genitourinary system
0.670 0.330 0.000
N00-N08 Glomerular diseases
0.669 0.331 0.000
E27 Other disorders of adrenal gland
0.669 0.331 0.000
N18.4 Chronic kidney disease, stage 4
0.669 0.331 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.668 0.332 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.668 0.332 0.000
I47 Paroxysmal tachycardia
0.667 0.333 0.000
C51-C58 Malignant neoplasms of female genital organs
0.667 0.333 0.000
Y84.2 Radiological procedure and radiotherapy
0.666 0.334 0.000
H00.1 Chalazion
0.666 0.334 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.665 0.335 0.000
M48.06 Spinal stenosis (Lumbar region)
0.665 0.335 0.000
C45 Mesothelioma
0.665 0.335 0.000
I61 Intracerebral haemorrhage
0.663 0.337 0.000
E03 Other hypothyroidism
0.662 0.338 0.000
D05 Carcinoma in situ of breast
0.662 0.338 0.000
R30 Pain associated with micturition
0.662 0.338 0.000
D55-D59 Haemolytic anaemias
0.661 0.339 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.661 0.339 0.000
O46.9 Antepartum haemorrhage, unspecified
0.661 0.339 0.000
M54.39 Sciatica (Site unspecified)
0.660 0.340 0.000
M54.8 Other dorsalgia
0.659 0.340 0.000
M54.6 Pain in thoracic spine
0.659 0.340 0.000
M54.0 Panniculitis affecting regions of neck and back
0.659 0.340 0.000
D75 Other diseases of blood and blood-forming organs
0.658 0.342 0.000
Chapter XXI Factors influencing health status and contact with health services
0.658 0.342 0.000
M21.3 Wrist or foot drop (acquired)
0.657 0.343 0.000
R06.8 Other and unspecified abnormalities of breathing
0.657 0.343 0.000
E65 Localised adiposity
0.656 0.344 0.000
I38 Endocarditis, valve unspecified
0.656 0.344 0.000
M54.16 Radiculopathy (Lumbar region)
0.656 0.344 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.655 0.344 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.653 0.347 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.653 0.347 0.000
O30 Multiple gestation
0.653 0.347 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.652 0.348 0.000
K61.0 Anal abscess
0.651 0.349 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.650 0.350 0.000
M41 Scoliosis
0.650 0.350 0.000
H49 Paralytic strabismus
0.650 0.350 0.000
O45 Premature separation of placenta [abruptio placentae]
0.650 0.350 0.000
O44 Placenta praevia
0.650 0.350 0.000
O43 Placental disorders
0.650 0.350 0.000
O41 Other disorders of amniotic fluid and membranes
0.650 0.350 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.650 0.350 0.000
O33 Maternal care for known or suspected disproportion
0.650 0.350 0.000
O31 Complications specific to multiple gestation
0.650 0.350 0.000
O40 Polyhydramnios
0.650 0.350 0.000
D09 Carcinoma in situ of other and unspecified sites
0.649 0.351 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.649 0.351 0.000
C78.7 Secondary malignant neoplasm of liver
0.648 0.352 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.648 0.352 0.000
H34 Retinal vascular occlusions
0.647 0.353 0.000
N19 Unspecified renal failure
0.647 0.353 0.000
O36.9 Maternal care for foetal problem, unspecified
0.647 0.353 0.000
B35-B49 Mycoses
0.647 0.353 0.000
S05.1 Contusion of eyeball and orbital tissues
0.643 0.356 0.000
O02.1 Missed abortion
0.643 0.357 0.000
G20-G26 Extrapyramidal and movement disorders
0.643 0.357 0.000
O47 False labour
0.643 0.357 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.642 0.358 0.000
M25.57 Pain in joint (Ankle and foot)
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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