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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17648606
log Bayes Factor = 18.9469
Chromosome 22   position 30,516,469  (GRCh37) Explore rs17648606 on Ensembl!
Variant rs17648606 is part of Cluster X0129

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
K29 Gastritis and duodenitis
0.999 0.001 0.000
I34 Nonrheumatic mitral valve disorders
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
I21 Acute myocardial infarction
0.993 0.007 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.991 0.009 0.000
I51 Complications and ill-defined descriptions of heart disease
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
K29.5 Chronic gastritis, unspecified
0.986 0.014 0.000
I34.0 Mitral (valve) insufficiency
0.986 0.014 0.000
G40-G47 Episodic and paroxysmal disorders
0.985 0.015 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.985 0.015 0.000
Z86 Personal history of certain other diseases
0.984 0.016 0.000
R50-R69 General symptoms and signs
0.982 0.018 0.000
I21.9 Acute myocardial infarction, unspecified
0.981 0.019 0.000
M50-M54 Other dorsopathies
0.974 0.026 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.973 0.027 0.000
Chapter II Neoplasms
0.968 0.032 0.000
K40-K46 Hernia
0.965 0.035 0.000
K55-K64 Other diseases of intestines
0.963 0.037 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.957 0.043 0.000
I51.7 Cardiomegaly
0.956 0.044 0.000
Z95.1 Presence of aortocoronary bypass graft
0.955 0.045 0.000
Z86.0 Personal history of other neoplasms
0.953 0.047 0.000
M54 Dorsalgia
0.951 0.049 0.000
K29.8 Duodenitis
0.946 0.054 0.000
R51 Headache
0.944 0.056 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.942 0.058 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.937 0.063 0.000
M70-M79 Other soft tissue disorders
0.934 0.066 0.000
K44 Diaphragmatic hernia
0.934 0.066 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.927 0.073 0.000
R63 Symptoms and signs concerning food and fluid intake
0.926 0.074 0.000
K57 Diverticular disease of intestine
0.925 0.075 0.000
Chapter X Diseases of the respiratory system
0.922 0.078 0.000
R20 Disturbances of skin sensation
0.921 0.079 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.916 0.084 0.000
I34.1 Mitral (valve) prolapse
0.914 0.086 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.912 0.088 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.912 0.088 0.000
Z95.2 Presence of prosthetic heart valve
0.911 0.089 0.000
I24 Other acute ischaemic heart diseases
0.906 0.094 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.905 0.095 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.899 0.101 0.000
G90-G99 Other disorders of the nervous system
0.896 0.104 0.000
K26 Duodenal ulcer
0.895 0.105 0.000
I51.8 Other ill-defined heart diseases
0.895 0.105 0.000
Z95.4 Presence of other heart-valve replacement
0.887 0.113 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.886 0.114 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.884 0.116 0.000
G43 Migraine
0.878 0.122 0.000
R53 Malaise and fatigue
0.877 0.123 0.000
C50-C50 Malignant neoplasm of breast
0.872 0.128 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.868 0.132 0.000
R56 Convulsions, not elsewhere classified
0.867 0.133 0.000
S00-S09 Injuries to the head
0.865 0.135 0.000
K29.1 Other acute gastritis
0.864 0.136 0.000
G35 Multiple sclerosis
0.864 0.136 0.000
K25 Gastric ulcer
0.862 0.138 0.000
M15-M19 Arthrosis
0.858 0.142 0.000
G40 Epilepsy
0.855 0.145 0.000
I25 Chronic ischaemic heart disease
0.854 0.146 0.000
M54.3 Sciatica
0.854 0.146 0.000
Chapter XX External causes of morbidity and mortality
0.853 0.147 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.853 0.147 0.000
I20 Angina pectoris
0.848 0.152 0.000
R20.2 Paraesthesia of skin
0.848 0.152 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.846 0.154 0.000
K43 Ventral hernia
0.842 0.158 0.000
K29.7 Gastritis, unspecified
0.840 0.160 0.000
M79.6 Pain in limb
0.838 0.162 0.000
I51.9 Heart disease, unspecified
0.838 0.162 0.000
M79.8 Other specified soft tissue disorders
0.837 0.163 0.000
M45-M49 Spondylopathies
0.836 0.164 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.835 0.165 0.000
Z86.4 Personal history of psychoactive substance abuse
0.834 0.166 0.000
M54.4 Lumbago with sciatica
0.833 0.167 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.833 0.167 0.000
K22 Other diseases of oesophagus
0.832 0.168 0.000
S20-S29 Injuries to the thorax
0.831 0.169 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.830 0.170 0.000
Chapter VIII Diseases of the ear and mastoid process
0.829 0.170 0.000
I50 Heart failure
0.827 0.173 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.826 0.174 0.000
G93 Other disorders of brain
0.826 0.174 0.000
K35-K38 Diseases of appendix
0.824 0.176 0.000
M05-M14 Inflammatory polyarthropathies
0.823 0.177 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.822 0.178 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.818 0.182 0.000
Z80 Family history of malignant neoplasm
0.816 0.184 0.000
D10-D36 Benign neoplasms
0.816 0.184 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.815 0.185 0.000
M54.9 Dorsalgia, unspecified
0.814 0.186 0.000
J90-J94 Other diseases of pleura
0.813 0.187 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.812 0.188 0.000
I22 Subsequent myocardial infarction
0.811 0.189 0.000
M65-M68 Disorders of synovium and tendon
0.810 0.190 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.810 0.190 0.000
M50 Cervical disk disorders
0.809 0.191 0.000
R63.4 Abnormal weight loss
0.809 0.191 0.000
K58 Irritable bowel syndrome
0.808 0.192 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.807 0.193 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.804 0.196 0.000
G47 Sleep disorders
0.804 0.196 0.000
S50-S59 Injuries to the elbow and forearm
0.804 0.196 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.803 0.197 0.000
C50 Malignant neoplasm of breast
0.803 0.197 0.000
Chapter I Certain infectious and parasitic diseases
0.802 0.198 0.000
K29.3 Chronic superficial gastritis
0.800 0.200 0.000
I10-I15 Hypertensive diseases
0.800 0.200 0.000
D22 Melanocytic naevi
0.796 0.204 0.000
Chapter VII Diseases of the eye and adnexa
0.796 0.204 0.000
G43.9 Migraine, unspecified
0.795 0.205 0.000
S00 Superficial injury of head
0.791 0.209 0.000
K61 Abscess of anal and rectal regions
0.791 0.209 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.791 0.209 0.000
I49 Other cardiac arrhythmias
0.790 0.210 0.000
D00-D09 In situ neoplasms
0.790 0.210 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.790 0.210 0.000
R63.0 Anorexia
0.790 0.210 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.788 0.212 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.788 0.212 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.787 0.212 0.000
M18 Arthrosis of first carpometacarpal joint
0.787 0.213 0.000
R23 Other skin changes
0.786 0.214 0.000
Z93 Artificial opening status
0.786 0.214 0.000
S90-S99 Injuries to the ankle and foot
0.786 0.214 0.000
R54 Senility
0.785 0.215 0.000
R56.8 Other and unspecified convulsions
0.784 0.216 0.000
M80-M85 Disorders of bone density and structure
0.782 0.218 0.000
M54.36 Sciatica (Lumbar region)
0.779 0.221 0.000
R14 Flatulence and related conditions
0.778 0.222 0.000
G41 Status epilepticus
0.777 0.223 0.000
Z95.3 Presence of xenogenic heart valve
0.777 0.223 0.000
C50.9 Breast, unspecified
0.776 0.224 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.776 0.224 0.000
G37 Other demyelinating diseases of central nervous system
0.773 0.227 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.771 0.229 0.000
K46 Unspecified abdominal hernia
0.771 0.229 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.770 0.230 0.000
K30 Dyspepsia
0.767 0.233 0.000
R60 Oedema, not elsewhere classified
0.767 0.233 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.766 0.234 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.764 0.236 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.762 0.238 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.761 0.239 0.000
R19.5 Other fecal abnormalities
0.760 0.240 0.000
M10 Gout
0.760 0.240 0.000
I35 Nonrheumatic aortic valve disorders
0.759 0.241 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.756 0.244 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.756 0.244 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.751 0.248 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.751 0.249 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.751 0.249 0.000
C79 Secondary malignant neoplasm of other sites
0.750 0.250 0.000
M40-M43 Deforming dorsopathies
0.749 0.250 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.749 0.251 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.749 0.251 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.746 0.254 0.000
R68 Other general symptoms and signs
0.745 0.254 0.000
K22.1 Ulcer of oesophagus
0.745 0.255 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.743 0.257 0.000
J90 Pleural effusion, not elsewhere classified
0.743 0.257 0.000
G44 Other headache syndromes
0.742 0.258 0.000
Z95.0 Presence of cardiac pacemaker
0.742 0.258 0.000
M54.5 Low back pain
0.741 0.259 0.000
K26.7 Chronic without haemorrhage or perforation
0.741 0.259 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.738 0.262 0.000
W00-W19 Falls
0.737 0.263 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.736 0.264 0.000
G93.3 Postviral fatigue syndrome
0.735 0.265 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.733 0.267 0.000
K41 Femoral hernia
0.731 0.268 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.730 0.269 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.730 0.270 0.000
Z99.8 Dependence on other enabling machines and devices
0.729 0.271 0.000
J40-J47 Chronic lower respiratory diseases
0.729 0.271 0.000
J60-J70 Lung diseases due to external agents
0.728 0.272 0.000
S00.8 Superficial injury of other parts of head
0.727 0.273 0.000
S32 Fracture of lumbar spine and pelvis
0.727 0.273 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.727 0.273 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.726 0.274 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.725 0.275 0.000
K29.4 Chronic atrophic gastritis
0.724 0.276 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.724 0.276 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.721 0.279 0.000
M54.2 Cervicalgia
0.721 0.279 0.000
M77 Other enthesopathies
0.721 0.279 0.000
I24.8 Other forms of acute ischaemic heart disease
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
D60-D64 Aplastic and other anaemias
0.716 0.284 0.000
K29.9 Gastroduodenitis, unspecified
0.716 0.284 0.000
K29.2 Alcoholic gastritis
0.716 0.284 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.715 0.285 0.000
K22.7 Barrett's oesophagus
0.715 0.285 0.000
I31 Other diseases of pericardium
0.715 0.285 0.000
R47-R49 Symptoms and signs involving speech and voice
0.715 0.285 0.000
M10.9 Gout, unspecified
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
M79.7 Fibromyalgia
0.714 0.286 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.714 0.286 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.714 0.286 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.714 0.286 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.712 0.288 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.712 0.288 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.712 0.288 0.000
Z89 Acquired absence of limb
0.712 0.288 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.712 0.288 0.000
S80-S89 Injuries to the knee and lower leg
0.711 0.289 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.710 0.289 0.000
E20-E35 Disorders of other endocrine glands
0.710 0.290 0.000
K29.0 Acute haemorrhagic gastritis
0.710 0.290 0.000
I51.6 Cardiovascular disease, unspecified
0.710 0.290 0.000
I51.5 Myocardial degeneration
0.710 0.290 0.000
I51.4 Myocarditis, unspecified
0.710 0.290 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.710 0.290 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.710 0.290 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.710 0.290 0.000
I51.0 Cardiac septal defect, acquired
0.710 0.290 0.000
Z80.3 Family history of malignant neoplasm of breast
0.710 0.290 0.000
Z98 Other postsurgical states
0.709 0.291 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.708 0.292 0.000
I25.1 Atherosclerotic heart disease
0.708 0.292 0.000
T33-T35 Frostbite
0.707 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.707 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.707 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.292 0.000
S10-S19 Injuries to the neck
0.707 0.292 0.000
I49.5 Sick sinus syndrome
0.707 0.293 0.000
M47 Spondylosis
0.707 0.293 0.000
S40-S49 Injuries to the shoulder and upper arm
0.706 0.294 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.706 0.294 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.706 0.294 0.000
J09-J18 Influenza and pneumonia
0.706 0.294 0.000
E50-E64 Other nutritional deficiencies
0.706 0.294 0.000
G47.3 Sleep apnoea
0.705 0.295 0.000
H43-H45 Disorders of vitreous body and globe
0.704 0.295 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.704 0.296 0.000
R62 Lack of expected normal physiological development
0.704 0.296 0.000
R57 Shock, not elsewhere classified
0.704 0.296 0.000
R64 Cachexia
0.704 0.296 0.000
R58 Haemorrhage, not elsewhere classified
0.704 0.296 0.000
J30-J39 Other diseases of upper respiratory tract
0.704 0.296 0.000
G30-G32 Other degenerative diseases of the nervous system
0.703 0.296 0.000
Z99.1 Dependence on respirator
0.703 0.297 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.703 0.297 0.000
S60-S69 Injuries to the wrist and hand
0.702 0.298 0.000
K65-K67 Diseases of peritoneum
0.701 0.299 0.000
I27 Other pulmonary heart diseases
0.700 0.300 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.700 0.300 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.699 0.300 0.000
G45.4 Transient global amnesia
0.699 0.301 0.000
S20 Superficial injury of thorax
0.699 0.301 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.699 0.301 0.000
M53 Other dorsopathies, not elsewhere classified
0.698 0.302 0.000
R50 Fever of unknown origin
0.695 0.305 0.000
G40.9 Epilepsy, unspecified
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.306 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.694 0.306 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.694 0.306 0.000
M65 Synovitis and tenosynovitis
0.694 0.306 0.000
R21 Rash and other nonspecific skin eruption
0.693 0.307 0.000
R15 Faecal incontinence
0.693 0.307 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.693 0.307 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.693 0.307 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.693 0.307 0.000
G80 Infantile cerebral palsy
0.693 0.307 0.000
K45 Other abdominal hernia
0.692 0.308 0.000
Z90.1 Acquired absence of breast(s)
0.692 0.308 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.692 0.308 0.000
H90-H95 Other disorders of ear
0.691 0.308 0.000
K25.3 Acute without haemorrhage or perforation
0.691 0.309 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.691 0.309 0.000
B95-B98 Bacterial, viral and other infectious agents
0.691 0.309 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.690 0.310 0.000
M71 Other bursopathies
0.690 0.310 0.000
M86-M90 Other osteopathies
0.690 0.310 0.000
I20.1 Angina pectoris with documented spasm
0.690 0.310 0.000
I47 Paroxysmal tachycardia
0.689 0.311 0.000
Z99.2 Dependence on renal dialysis
0.688 0.312 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.688 0.312 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.686 0.314 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.686 0.314 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.686 0.314 0.000
M79.69 Pain in limb (Site unspecified)
0.685 0.315 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.685 0.315 0.000
M79.64 Pain in limb (Hand)
0.685 0.315 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.684 0.316 0.000
D05 Carcinoma in situ of breast
0.684 0.316 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.684 0.316 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.684 0.316 0.000
I21.4 Acute subendocardial myocardial infarction
0.683 0.317 0.000
C15-C26 Malignant neoplasms of digestive organs
0.683 0.317 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.683 0.317 0.000
M54.8 Other dorsalgia
0.682 0.318 0.000
M54.6 Pain in thoracic spine
0.682 0.318 0.000
M54.0 Panniculitis affecting regions of neck and back
0.682 0.318 0.000
I05-I09 Chronic rheumatic heart diseases
0.682 0.318 0.000
K55 Vascular disorders of intestine
0.679 0.321 0.000
G20-G26 Extrapyramidal and movement disorders
0.679 0.321 0.000
I50.1 Left ventricular failure
0.679 0.321 0.000
B35-B49 Mycoses
0.678 0.322 0.000
G60 Hereditary and idiopathic neuropathy
0.678 0.322 0.000
I38 Endocarditis, valve unspecified
0.678 0.322 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.678 0.322 0.000
I46 Cardiac arrest
0.677 0.323 0.000
M79.62 Pain in limb (Upper arm)
0.677 0.323 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.677 0.323 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.677 0.323 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.676 0.324 0.000
Z60 Problems related to social environment
0.676 0.324 0.000
K27 Peptic ulcer, site unspecified
0.676 0.324 0.000
Z99.3 Dependence on wheelchair
0.675 0.325 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.675 0.325 0.000
K20 Oesophagitis
0.674 0.326 0.000
G45.3 Amaurosis fugax
0.673 0.327 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.673 0.327 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.672 0.327 0.000
G36 Other acute disseminated demyelination
0.671 0.328 0.000
I50.0 Congestive heart failure
0.671 0.329 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.671 0.329 0.000
M79.0 Rheumatism, unspecified
0.671 0.329 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.670 0.330 0.000
M76 Enthesopathies of lower limb, excluding foot
0.670 0.330 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.670 0.330 0.000
K44.1 Diaphragmatic hernia with gangrene
0.669 0.330 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.669 0.330 0.000
K61.0 Anal abscess
0.668 0.332 0.000
H65-H75 Diseases of middle ear and mastoid
0.666 0.334 0.000
I20.9 Angina pectoris, unspecified
0.666 0.334 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.665 0.335 0.000
S09 Other and unspecified injuries of head
0.665 0.335 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.664 0.336 0.000
R63.5 Abnormal weight gain
0.664 0.336 0.000
R63.3 Feeding difficulties and mismanagement
0.664 0.336 0.000
R63.2 Polyphagia
0.664 0.336 0.000
R63.1 Polydipsia
0.664 0.336 0.000
J20-J22 Other acute lower respiratory infections
0.663 0.337 0.000
C60-C63 Malignant neoplasms of male genital organs
0.663 0.337 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.663 0.337 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.663 0.337 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.663 0.337 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.663 0.337 0.000
K26.3 Acute without haemorrhage or perforation
0.663 0.337 0.000
R20.3 Hyperaesthesia
0.660 0.340 0.000
R20.1 Hypoaesthesia of skin
0.660 0.340 0.000
R20.0 Anaesthesia of skin
0.660 0.340 0.000
M79.60 Pain in limb (Multiple sites)
0.660 0.340 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.659 0.341 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.659 0.341 0.000
C71 Malignant neoplasm of brain
0.659 0.341 0.000
D22.9 Melanocytic naevi, unspecified
0.658 0.342 0.000
M10.99 Gout, unspecified (Site unspecified)
0.657 0.343 0.000
K29.6 Other gastritis
0.657 0.343 0.000
S51 Open wound of forearm
0.656 0.344 0.000
D45 Polycythaemia vera
0.656 0.344 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.656 0.344 0.000
G62 Other polyneuropathies
0.655 0.345 0.000
K35 Acute appendicitis
0.655 0.345 0.000
M20-M25 Other joint disorders
0.655 0.345 0.000
M79.9 Soft tissue disorder, unspecified
0.654 0.346 0.000
M79.5 Residual foreign body in soft tissue
0.654 0.346 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.654 0.346 0.000
M79.3 Panniculitis, unspecified
0.654 0.346 0.000
M79.2 Neuralgia and neuritis, unspecified
0.654 0.346 0.000
M79.1 Myalgia
0.654 0.346 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.654 0.346 0.000
W19 Unspecified fall
0.654 0.346 0.000
Z83 Family history of other specific disorders
0.654 0.346 0.000
Z91.6 Personal history of other physical trauma
0.654 0.346 0.000
M54.1 Radiculopathy
0.653 0.347 0.000
I25.5 Ischaemic cardiomyopathy
0.653 0.347 0.000
K56.7 Ileus, unspecified
0.653 0.347 0.000
G93.8 Other specified disorders of brain
0.652 0.348 0.000
G93.4 Encephalopathy, unspecified
0.652 0.348 0.000
G91 Hydrocephalus
0.652 0.348 0.000
I60-I69 Cerebrovascular diseases
0.651 0.349 0.000
K56.6 Other and unspecified intestinal obstruction
0.651 0.349 0.000
D34 Benign neoplasm of thyroid gland
0.650 0.350 0.000
I24.1 Dressler's syndrome
0.649 0.350 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.649 0.351 0.000
R52 Pain, not elsewhere classified
0.649 0.351 0.000
Z97 Presence of other devices
0.649 0.351 0.000
V80-V89 Other land transport accidents
0.648 0.352 0.000
K22.2 Oesophageal obstruction
0.647 0.353 0.000
E40-E46 Malnutrition
0.647 0.353 0.000
S70-S79 Injuries to the hip and thigh
0.647 0.353 0.000
G43.1 Migraine with aura [classical migraine]
0.647 0.353 0.000
M50.2 Other cervical disk displacement
0.647 0.353 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.646 0.354 0.000
K63 Other diseases of intestine
0.645 0.355 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.645 0.355 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.645 0.355 0.000
J95-J99 Other diseases of the respiratory system
0.644 0.356 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.356 0.000
R22.0 Localised swelling, mass and lump, head
0.643 0.357 0.000
R23.3 Spontaneous ecchymoses
0.643 0.357 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.643 0.357 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.643 0.357 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
G96 Other disorders of central nervous system
0.642 0.358 0.000
G95 Other diseases of spinal cord
0.642 0.358 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.642 0.358 0.000
G90 Disorders of autonomic nervous system
0.642 0.358 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
G92 Toxic encephalopathy
0.642 0.358 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.642 0.358 0.000
K26.5 Chronic or unspecified with perforation
0.642 0.358 0.000
K26.4 Chronic or unspecified with haemorrhage
0.642 0.358 0.000
K26.2 Acute with both haemorrhage and perforation
0.642 0.358 0.000
K26.1 Acute with perforation
0.642 0.358 0.000
K26.0 Acute with haemorrhage
0.642 0.358 0.000
R18 Ascites
0.641 0.359 0.000
S92 Fracture of foot, except ankle
0.641 0.359 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.641 0.359 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.640 0.360 0.000
M72 Fibroblastic disorders
0.639 0.360 0.000
W20-W49 Exposure to inanimate mechanical forces
0.639 0.361 0.000
I20.0 Unstable angina
0.639 0.361 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.638 0.361 0.000
E70-E90 Metabolic disorders
0.638 0.362 0.000
D64 Other anaemias
0.637 0.362 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.637 0.363 0.000
K70-K77 Diseases of liver
0.637 0.363 0.000
Z90.5 Acquired absence of kidney
0.637 0.363 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.635 0.364 0.000
Z99.4 Dependence on artificial heart
0.635 0.364 0.000
Z99.0 Dependence on aspirator
0.635 0.364 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.635 0.365 0.000
M46 Other inflammatory spondylopathies
0.634 0.366 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.634 0.366 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.634 0.366 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.634 0.366 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.634 0.366 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.634 0.366 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.634 0.366 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.634 0.366 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.634 0.366 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.634 0.366 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.634 0.366 0.000
T36 Poisoning by systemic antibiotics
0.634 0.366 0.000
C64-C68 Malignant neoplasms of urinary tract
0.634 0.366 0.000
S06 Intracranial injury
0.634 0.366 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.634 0.366 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.633 0.367 0.000
I10 Essential (primary) hypertension
0.632 0.368 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.632 0.368 0.000
K38 Other diseases of appendix
0.631 0.369 0.000
G43.8 Other migraine
0.629 0.371 0.000
G43.3 Complicated migraine
0.629 0.371 0.000
G43.2 Status migrainosus
0.629 0.371 0.000
G43.0 Migraine without aura [common migraine]
0.629 0.371 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.629 0.371 0.000
M54.39 Sciatica (Site unspecified)
0.628 0.372 0.000
G41.9 Status epilepticus, unspecified
0.628 0.372 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.626 0.374 0.000
M79.66 Pain in limb (Lower leg)
0.626 0.374 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.626 0.374 0.000
Z50 Care involving use of rehabilitation procedures
0.625 0.375 0.000
K05 Gingivitis and periodontal diseases
0.625 0.375 0.000
G61 Inflammatory polyneuropathy
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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