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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17843975
log Bayes Factor = 13.0672
Chromosome 4   position 159,628,522  (GRCh37) Explore rs17843975 on Ensembl!
Variant rs17843975 is part of Cluster X0074

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
F32 Depressive episode
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
F32.9 Depressive episode, unspecified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
Chapter II Neoplasms
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.989 0.011 0.000
C15-C26 Malignant neoplasms of digestive organs
0.984 0.016 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
M45-M49 Spondylopathies
0.982 0.018 0.000
M54 Dorsalgia
0.980 0.020 0.000
S02 Fracture of skull and facial bones
0.977 0.023 0.000
M48 Other spondylopathies
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.975 0.025 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.972 0.028 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.971 0.029 0.000
M48.0 Spinal stenosis
0.971 0.029 0.000
C15 Malignant neoplasm of oesophagus
0.967 0.033 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.967 0.033 0.000
A00-A09 Intestinal infectious diseases
0.962 0.038 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.961 0.039 0.000
M48.06 Spinal stenosis (Lumbar region)
0.961 0.039 0.000
S06 Intracranial injury
0.949 0.051 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.948 0.052 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.946 0.054 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.946 0.054 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.944 0.056 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.942 0.058 0.000
M15-M19 Arthrosis
0.937 0.063 0.000
F17.1 Harmful use
0.936 0.064 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.933 0.067 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.932 0.068 0.000
F33 Recurrent depressive disorder
0.932 0.068 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.931 0.069 0.000
F41 Other anxiety disorders
0.923 0.077 0.000
I10-I15 Hypertensive diseases
0.921 0.079 0.000
R47-R49 Symptoms and signs involving speech and voice
0.919 0.081 0.000
M54.1 Radiculopathy
0.911 0.089 0.000
C51-C58 Malignant neoplasms of female genital organs
0.909 0.091 0.000
M19 Other arthrosis
0.908 0.092 0.000
I12 Hypertensive renal disease
0.902 0.098 0.000
C34 Malignant neoplasm of bronchus and lung
0.901 0.099 0.000
R94 Abnormal results of function studies
0.901 0.099 0.000
M54.3 Sciatica
0.900 0.100 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.900 0.100 0.000
C15.9 Oesophagus, unspecified
0.895 0.105 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.893 0.107 0.000
M70-M79 Other soft tissue disorders
0.890 0.110 0.000
M54.2 Cervicalgia
0.884 0.116 0.000
M19.0 Primary arthrosis of other joints
0.884 0.116 0.000
M86-M90 Other osteopathies
0.883 0.117 0.000
F17.2 Dependence syndrome
0.883 0.117 0.000
Chapter XXI Factors influencing health status and contact with health services
0.881 0.119 0.000
I12.0 Hypertensive renal disease with renal failure
0.878 0.122 0.000
I71 Aortic aneurysm and dissection
0.877 0.123 0.000
S02.8 Fractures of other skull and facial bones
0.877 0.123 0.000
R49 Voice disturbances
0.875 0.125 0.000
M80-M85 Disorders of bone density and structure
0.872 0.128 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.872 0.128 0.000
Chapter XIV Diseases of the genitourinary system
0.871 0.129 0.000
C15.5 Lower third of oesophagus
0.868 0.132 0.000
I60-I69 Cerebrovascular diseases
0.866 0.134 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.865 0.135 0.000
S02.4 Fracture of malar and maxillary bones
0.861 0.139 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.861 0.139 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.860 0.140 0.000
Q60-Q64 Congenital malformations of the urinary system
0.855 0.145 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.850 0.150 0.000
N93 Other abnormal uterine and vaginal bleeding
0.849 0.151 0.000
C54 Malignant neoplasm of corpus uteri
0.847 0.153 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.847 0.153 0.000
R49.0 Dysphonia
0.844 0.156 0.000
N81 Female genital prolapse
0.843 0.157 0.000
R94.5 Abnormal results of liver function studies
0.843 0.157 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.842 0.158 0.000
S60-S69 Injuries to the wrist and hand
0.842 0.158 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.841 0.159 0.000
I74 Arterial embolism and thrombosis
0.841 0.159 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.841 0.159 0.000
N80 Endometriosis
0.841 0.159 0.000
M54.5 Low back pain
0.840 0.160 0.000
M72 Fibroblastic disorders
0.838 0.162 0.000
C15.4 Middle third of oesophagus
0.838 0.162 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.837 0.163 0.000
N25-N29 Other disorders of kidney and ureter
0.835 0.165 0.000
A08 Viral and other specified intestinal infections
0.834 0.166 0.000
F41.9 Anxiety disorder, unspecified
0.833 0.167 0.000
Z46 Fitting and adjustment of other devices
0.832 0.168 0.000
M54.16 Radiculopathy (Lumbar region)
0.832 0.168 0.000
F03 Unspecified dementia
0.830 0.170 0.000
F45 Somatoform disorders
0.830 0.170 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.827 0.173 0.000
M19.1 Posttraumatic arthrosis of other joints
0.826 0.174 0.000
S01 Open wound of head
0.824 0.176 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.823 0.177 0.000
N81.1 Cystocele
0.823 0.177 0.000
S00 Superficial injury of head
0.821 0.179 0.000
Z46.6 Fitting and adjustment of urinary device
0.820 0.180 0.000
I60 Subarachnoid haemorrhage
0.818 0.182 0.000
C21 Malignant neoplasm of anus and anal canal
0.817 0.183 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.817 0.183 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.816 0.184 0.000
M51 Other intervertebral disk disorders
0.815 0.185 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.815 0.185 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.815 0.185 0.000
R47 Speech disturbances, not elsewhere classified
0.814 0.186 0.000
F25 Schizoaffective disorders
0.813 0.187 0.000
S02.1 Fracture of base of skull
0.813 0.187 0.000
F32.0 Mild depressive episode
0.812 0.188 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.805 0.194 0.000
C54.1 Endometrium
0.803 0.197 0.000
I30-I52 Other forms of heart disease
0.801 0.199 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.800 0.199 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.798 0.202 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.796 0.204 0.000
S06.5 Traumatic subdural haemorrhage
0.796 0.204 0.000
F43 Reaction to severe stress, and adjustment disorders
0.794 0.206 0.000
R94.3 Abnormal results of cardiovascular function studies
0.794 0.206 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.794 0.206 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.794 0.206 0.000
S05 Injury of eye and orbit
0.793 0.207 0.000
F31 Bipolar affective disorder
0.793 0.207 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.792 0.208 0.000
M54.22 Cervicalgia (Cervical region)
0.792 0.208 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.791 0.209 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.790 0.210 0.000
Q61 Cystic kidney disease
0.789 0.211 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.789 0.211 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.788 0.212 0.000
C34.1 Upper lobe, bronchus or lung
0.788 0.212 0.000
F33.9 Recurrent depressive disorder, unspecified
0.787 0.213 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.787 0.213 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.787 0.213 0.000
M81 Osteoporosis without pathological fracture
0.784 0.216 0.000
S06.2 Diffuse brain injury
0.782 0.218 0.000
I05-I09 Chronic rheumatic heart diseases
0.780 0.220 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.779 0.221 0.000
M40-M43 Deforming dorsopathies
0.779 0.221 0.000
A80-A89 Viral infections of the central nervous system
0.778 0.222 0.000
F34 Persistent mood [affective] disorders
0.778 0.222 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.778 0.222 0.000
S80-S89 Injuries to the knee and lower leg
0.778 0.222 0.000
N85.4 Malposition of uterus
0.778 0.222 0.000
S02.0 Fracture of vault of skull
0.777 0.223 0.000
Z75 Problems related to medical facilities and other health care
0.777 0.223 0.000
N80.3 Endometriosis of pelvic peritoneum
0.777 0.223 0.000
C16 Malignant neoplasm of stomach
0.775 0.225 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.775 0.225 0.000
N81.4 Uterovaginal prolapse, unspecified
0.773 0.227 0.000
C50-C50 Malignant neoplasm of breast
0.772 0.228 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.770 0.230 0.000
S50-S59 Injuries to the elbow and forearm
0.770 0.230 0.000
N95 Menopausal and other perimenopausal disorders
0.770 0.230 0.000
C34.3 Lower lobe, bronchus or lung
0.769 0.231 0.000
M54.12 Radiculopathy (Cervical region)
0.769 0.231 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.768 0.232 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.768 0.232 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.768 0.232 0.000
Z49 Care involving dialysis
0.766 0.234 0.000
Chapter VIII Diseases of the ear and mastoid process
0.765 0.235 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.764 0.236 0.000
S01.9 Open wound of head, part unspecified
0.764 0.236 0.000
F41.2 Mixed anxiety and depressive disorder
0.763 0.237 0.000
M54.39 Sciatica (Site unspecified)
0.763 0.237 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.762 0.238 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.762 0.238 0.000
M91-M94 Chondropathies
0.761 0.239 0.000
N28.8 Other specified disorders of kidney and ureter
0.758 0.242 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.757 0.243 0.000
I49 Other cardiac arrhythmias
0.756 0.244 0.000
M48.02 Spinal stenosis (Cervical region)
0.754 0.246 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.754 0.246 0.000
I12.9 Hypertensive renal disease without renal failure
0.754 0.246 0.000
I95 Hypotension
0.753 0.247 0.000
S02.3 Fracture of orbital floor
0.753 0.247 0.000
C23 Malignant neoplasm of gallbladder
0.752 0.248 0.000
F22 Persistent delusional disorders
0.751 0.249 0.000
F32.1 Moderate depressive episode
0.747 0.253 0.000
M89 Other disorders of bone
0.747 0.253 0.000
A02 Other Salmonella infections
0.746 0.254 0.000
C34.9 Bronchus or lung, unspecified
0.745 0.255 0.000
C32 Malignant neoplasm of larynx
0.745 0.255 0.000
I51 Complications and ill-defined descriptions of heart disease
0.745 0.255 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.744 0.256 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.744 0.256 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.744 0.256 0.000
Chapter XXII Codes for special purposes
0.743 0.257 0.000
M60-M63 Disorders of muscles
0.742 0.258 0.000
S06.8 Other intracranial injuries
0.741 0.259 0.000
M54.36 Sciatica (Lumbar region)
0.739 0.261 0.000
M15 Polyarthrosis
0.738 0.261 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.738 0.262 0.000
Z48 Other surgical follow-up care
0.738 0.262 0.000
S01.8 Open wound of other parts of head
0.737 0.263 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.737 0.263 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.737 0.263 0.000
M53 Other dorsopathies, not elsewhere classified
0.736 0.264 0.000
N85.0 Endometrial glandular hyperplasia
0.736 0.264 0.000
F05.9 Delirium, unspecified
0.735 0.265 0.000
M18 Arthrosis of first carpometacarpal joint
0.735 0.265 0.000
M88 Paget's disease of bone [osteitis deformans]
0.734 0.266 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.734 0.266 0.000
B35-B49 Mycoses
0.733 0.267 0.000
I72 Other aneurysm
0.733 0.267 0.000
S06.3 Focal brain injury
0.732 0.268 0.000
M54.37 Sciatica (Lumbosacral region)
0.732 0.268 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.732 0.268 0.000
F60-F69 Disorders of adult personality and behaviour
0.732 0.268 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.732 0.268 0.000
Q80-Q89 Other congenital malformations
0.731 0.269 0.000
M54.57 Low back pain (Lumbosacral region)
0.731 0.269 0.000
S60 Superficial injury of wrist and hand
0.731 0.269 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.731 0.269 0.000
Z63 Other problems related to primary support group, including family circumstances
0.730 0.269 0.000
Q50-Q56 Congenital malformations of genital organs
0.729 0.271 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.728 0.271 0.000
F45.8 Other somatoform disorders
0.728 0.271 0.000
S02.6 Fracture of mandible
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.728 0.272 0.000
C56 Malignant neoplasm of ovary
0.727 0.273 0.000
M51.2 Other specified intervertebral disk displacement
0.727 0.273 0.000
F42 Obsessive-compulsive disorder
0.725 0.275 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.725 0.275 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.724 0.276 0.000
M81.9 Osteoporosis, unspecified
0.723 0.277 0.000
R47.0 Dysphasia and aphasia
0.723 0.277 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.722 0.278 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.721 0.279 0.000
C20 Malignant neoplasm of rectum
0.721 0.279 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.719 0.281 0.000
F00 Dementia in Alzheimer's disease
0.718 0.282 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
F30 Manic episode
0.717 0.283 0.000
F39 Unspecified mood [affective] disorder
0.717 0.283 0.000
F32.8 Other depressive episodes
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
R79 Other abnormal findings of blood chemistry
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.715 0.285 0.000
S07 Crushing injury of head
0.715 0.285 0.000
S04 Injury of cranial nerves
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.712 0.288 0.000
F01 Vascular dementia
0.711 0.289 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.709 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.709 0.291 0.000
F06.7 Mild cognitive disorder
0.709 0.291 0.000
I42 Cardiomyopathy
0.708 0.291 0.000
D47.2 Monoclonal gammopathy
0.708 0.292 0.000
I74.8 Embolism and thrombosis of other arteries
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.293 0.000
I34 Nonrheumatic mitral valve disorders
0.707 0.293 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
C17 Malignant neoplasm of small intestine
0.705 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
M49 Spondylopathies in diseases classified elsewhere
0.704 0.295 0.000
M16 Coxarthrosis [arthrosis of hip]
0.704 0.296 0.000
Q61.2 Polycystic kidney, adult type
0.703 0.297 0.000
I11 Hypertensive heart disease
0.703 0.297 0.000
M54.8 Other dorsalgia
0.702 0.298 0.000
M54.0 Panniculitis affecting regions of neck and back
0.702 0.298 0.000
Z52 Donors of organs and tissues
0.702 0.298 0.000
F23 Acute and transient psychotic disorders
0.702 0.298 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.702 0.298 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.700 0.300 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.700 0.300 0.000
S02.7 Multiple fractures involving skull and facial bones
0.700 0.300 0.000
F80-F89 Disorders of psychological development
0.700 0.300 0.000
M48.9 Spondylopathy, unspecified
0.700 0.300 0.000
M48.8 Other specified spondylopathies
0.700 0.300 0.000
M48.4 Fatigue fracture of vertebra
0.700 0.300 0.000
M48.3 Traumatic spondylopathy
0.700 0.300 0.000
M48.2 Kissing spine
0.700 0.300 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.700 0.300 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.700 0.300 0.000
M54.9 Dorsalgia, unspecified
0.699 0.301 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.699 0.301 0.000
B65-B83 Helminthiases
0.699 0.301 0.000
B50-B64 Protozoal diseases
0.699 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.699 0.301 0.000
A75-A79 Rickettsioses
0.699 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.699 0.301 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
I95.9 Hypotension, unspecified
0.699 0.301 0.000
H65-H75 Diseases of middle ear and mastoid
0.698 0.302 0.000
M54.29 Cervicalgia-Site unspe
0.698 0.302 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.697 0.303 0.000
C21.0 Anus, unspecified
0.697 0.303 0.000
N80.8 Other endometriosis
0.697 0.303 0.000
T91 Sequelae of injuries of neck and trunk
0.697 0.303 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.697 0.303 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.697 0.303 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.697 0.303 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.697 0.303 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.697 0.303 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.697 0.303 0.000
F11 Mental and behavioural disorders due to use of opioids
0.697 0.303 0.000
F48 Other neurotic disorders
0.696 0.304 0.000
F44 Dissociative [conversion] disorders
0.696 0.304 0.000
F25.9 Schizoaffective disorder, unspecified
0.696 0.304 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.696 0.304 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.696 0.304 0.000
M48.04 Spinal stenosis (Thoracic region)
0.696 0.304 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.696 0.304 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.696 0.304 0.000
Z74 Problems related to care-provider dependency
0.696 0.304 0.000
S61 Open wound of wrist and hand
0.695 0.305 0.000
S02.10 Fracture of base of skull (closed)
0.695 0.305 0.000
N80.1 Endometriosis of ovary
0.694 0.306 0.000
C15.8 Overlapping lesion of oesophagus
0.693 0.307 0.000
C15.3 Upper third of oesophagus
0.693 0.307 0.000
C15.2 Abdominal part of oesophagus
0.693 0.307 0.000
C15.1 Thoracic part of oesophagus
0.693 0.307 0.000
C15.0 Cervical part of oesophagus
0.693 0.307 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.693 0.307 0.000
F02 Dementia in other diseases classified elsewhere
0.693 0.307 0.000
F09 Unspecified organic or symptomatic mental disorder
0.693 0.307 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.693 0.307 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.693 0.307 0.000
F25.1 Schizoaffective disorder, depressive type
0.692 0.308 0.000
C51 Malignant neoplasm of vulva
0.692 0.308 0.000
Z40 Prophylactic surgery
0.691 0.309 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.691 0.309 0.000
A07 Other protozoal intestinal diseases
0.690 0.310 0.000
A06 Amoebiasis
0.690 0.310 0.000
A05 Other bacterial foodborne intoxications
0.690 0.310 0.000
A03 Shigellosis
0.690 0.310 0.000
A01 Typhoid and paratyphoid fevers
0.690 0.310 0.000
A00 Cholera
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.689 0.310 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.690 0.310 0.000
F17.9 Unspecified mental and behavioural disorder
0.689 0.311 0.000
F17.8 Other mental and behavioural disorders
0.689 0.311 0.000
F17.7 Residual and late-onset psychotic disorder
0.689 0.311 0.000
F17.6 Amnesic syndrome
0.689 0.311 0.000
F17.5 Psychotic disorder
0.689 0.311 0.000
F17.4 Withdrawal state with delirium
0.689 0.311 0.000
F17.3 Withdrawal state
0.689 0.311 0.000
F17.0 Acute intoxication
0.689 0.311 0.000
C34.2 Middle lobe, bronchus or lung
0.689 0.311 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.689 0.311 0.000
I69 Sequelae of cerebrovascular disease
0.689 0.311 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.688 0.312 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.688 0.312 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.687 0.313 0.000
M77 Other enthesopathies
0.687 0.313 0.000
N95.3 States associated with artificial menopause
0.686 0.314 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.686 0.314 0.000
I49.5 Sick sinus syndrome
0.686 0.314 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.685 0.315 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.684 0.316 0.000
Q61.3 Polycystic kidney, unspecified
0.684 0.316 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.684 0.316 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
F05.0 Delirium not superimposed on dementia, so described
0.683 0.317 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.683 0.317 0.000
F43.2 Adjustment disorders
0.682 0.318 0.000
Q21 Congenital malformations of cardiac septa
0.681 0.319 0.000
S02.2 Fracture of nasal bones
0.681 0.319 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.680 0.319 0.000
F05.8 Other delirium
0.680 0.320 0.000
S06.9 Intracranial injury, unspecified
0.680 0.320 0.000
S06.7 Intracranial injury with prolonged coma
0.680 0.320 0.000
S06.4 Epidural haemorrhage
0.680 0.320 0.000
S06.1 Traumatic cerebral oedema
0.680 0.320 0.000
S06.0 Concussion
0.680 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.680 0.320 0.000
Q35-Q37 Cleft lip and cleft palate
0.680 0.320 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.680 0.320 0.000
M76 Enthesopathies of lower limb, excluding foot
0.680 0.320 0.000
A08.3 Other viral enteritis
0.679 0.321 0.000
M48.09 Spinal stenosis (Site unspecified)
0.679 0.321 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.678 0.322 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.678 0.322 0.000
C31 Malignant neoplasm of accessory sinuses
0.678 0.322 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.678 0.322 0.000
C37 Malignant neoplasm of thymus
0.678 0.322 0.000
C33 Malignant neoplasm of trachea
0.678 0.322 0.000
Z49.1 Extracorporeal dialysis
0.678 0.322 0.000
S02.5 Fracture of tooth
0.677 0.322 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.676 0.323 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.676 0.324 0.000
M41 Scoliosis
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.674 0.326 0.000
S90-S99 Injuries to the ankle and foot
0.674 0.326 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.674 0.326 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.674 0.326 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.674 0.326 0.000
Z51 Other medical care
0.673 0.327 0.000
C71 Malignant neoplasm of brain
0.672 0.328 0.000
N26 Unspecified contracted kidney
0.670 0.330 0.000
I15 Secondary hypertension
0.670 0.330 0.000
F33.8 Other recurrent depressive disorders
0.668 0.332 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.668 0.332 0.000
Z57 Occupational exposure to risk-factors
0.668 0.332 0.000
M16.1 Other primary coxarthrosis
0.667 0.333 0.000
B15-B19 Viral hepatitis
0.666 0.333 0.000
R73 Elevated blood glucose level
0.666 0.334 0.000
S62 Fracture at wrist and hand level
0.665 0.335 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.665 0.335 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.665 0.335 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.664 0.335 0.000
T93 Sequelae of injuries of lower limb
0.664 0.336 0.000
M47 Spondylosis
0.664 0.336 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.663 0.337 0.000
A30-A49 Other bacterial diseases
0.662 0.338 0.000
F41.8 Other specified anxiety disorders
0.662 0.338 0.000
F41.3 Other mixed anxiety disorders
0.662 0.338 0.000
I13 Hypertensive heart and renal disease
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.659 0.341 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.659 0.341 0.000
Z54 Convalescence
0.659 0.341 0.000
S00.9 Superficial injury of head, part unspecified
0.658 0.342 0.000
N81.6 Rectocele
0.658 0.342 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.657 0.343 0.000
Z59 Problems related to housing and economic circumstances
0.657 0.343 0.000
I49.9 Cardiac arrhythmia, unspecified
0.656 0.344 0.000
M54.56 Low back pain (Lumbar region)
0.654 0.346 0.000
I42.2 Other hypertrophic cardiomyopathy
0.654 0.346 0.000
H72 Perforation of tympanic membrane
0.654 0.346 0.000
M54.19 Radiculopathy (Site unspecified)
0.653 0.347 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.653 0.347 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.653 0.347 0.000
M54.14 Radiculopathy (Thoracic region)
0.653 0.347 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.653 0.347 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.653 0.347 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.653 0.347 0.000
M84 Disorders of continuity of bone
0.653 0.347 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.652 0.348 0.000
C58 Malignant neoplasm of placenta
0.652 0.348 0.000
C52 Malignant neoplasm of vagina
0.652 0.348 0.000
S60.8 Other superficial injuries of wrist and hand
0.652 0.348 0.000
S40 Superficial injury of shoulder and upper arm
0.651 0.349 0.000
M19.8 Other specified arthrosis
0.651 0.349 0.000
M19.2 Other secondary arthrosis
0.651 0.349 0.000
R47.8 Other and unspecified speech disturbances
0.651 0.349 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.649 0.351 0.000
I51.7 Cardiomegaly
0.649 0.351 0.000
M87 Osteonecrosis
0.649 0.351 0.000
N80.0 Endometriosis of uterus
0.649 0.351 0.000
N81.8 Other female genital prolapse
0.648 0.352 0.000
N85.6 Intra-uterine synechiae
0.648 0.352 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.648 0.352 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.647 0.353 0.000
Z51.5 Palliative care
0.647 0.353 0.000
S05.1 Contusion of eyeball and orbital tissues
0.647 0.353 0.000
C34.8 Overlapping lesion of bronchus and lung
0.646 0.354 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.646 0.354 0.000
R94.7 Abnormal results of other endocrine function studies
0.646 0.354 0.000
R94.6 Abnormal results of thyroid function studies
0.646 0.354 0.000
R94.2 Abnormal results of pulmonary function studies
0.646 0.354 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.646 0.354 0.000
R94.0 Abnormal results of function studies of central nervous system
0.646 0.354 0.000
I45 Other conduction disorders
0.645 0.355 0.000
S03.2 Dislocation of tooth
0.645 0.355 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.645 0.355 0.000
M54.35 Sciatica (Thoracolumbar region)
0.645 0.355 0.000
M54.34 Sciatica-Thoracic
0.645 0.355 0.000
M54.33 Sciatica-Cervicothoracic
0.645 0.355 0.000
M54.32 Sciatica-Cervical
0.645 0.355 0.000
M54.31 Sciatica-Occipit-atl-axl
0.645 0.355 0.000
M54.30 Sciatica (Multiple sites in spine)
0.645 0.355 0.000
F28 Other nonorganic psychotic disorders
0.645 0.355 0.000
F24 Induced delusional disorder
0.645 0.355 0.000
F21 Schizotypal disorder
0.645 0.355 0.000
Q25 Congenital malformations of great arteries
0.645 0.355 0.000
F22.0 Delusional disorder
0.644 0.356 0.000
F99-F99 Unspecified mental disorder
0.644 0.356 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
M90 Osteopathies in diseases classified elsewhere
0.642 0.357 0.000
D47.1 Chronic myeloproliferative disease
0.642 0.358 0.000
Q00-Q07 Congenital malformations of the nervous system
0.641 0.359 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.641 0.359 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.640 0.360 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.640 0.360 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.640 0.360 0.000
I34.0 Mitral (valve) insufficiency
0.639 0.361 0.000
D00-D09 In situ neoplasms
0.639 0.361 0.000
Z63.4 Disappearance and death of family member
0.638 0.362 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.638 0.362 0.000
A87 Viral meningitis
0.637 0.362 0.000
M80 Osteoporosis with pathological fracture
0.637 0.363 0.000
B91 Sequelae of poliomyelitis
0.637 0.363 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.637 0.363 0.000
I61 Intracerebral haemorrhage
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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