TreeWAS – Variant ID: rs1800562

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
D45 Polycythaemia vera	1.000	0.000	0.000
K70-K77 Diseases of liver	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000	0.000
K76 Other diseases of liver	1.000	0.000	0.000
K74 Fibrosis and cirrhosis of liver	1.000	0.000	0.000
L00-L08 Infections of the skin and subcutaneous tissue	1.000	0.000	0.000
M15-M19 Arthrosis	1.000	0.000	0.000
G35-G37 Demyelinating diseases of the central nervous system	1.000	0.000	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
L03 Cellulitis	0.999	0.001	0.000
G35 Multiple sclerosis	0.999	0.001	0.000
K74.6 Other and unspecified cirrhosis of liver	0.999	0.001	0.000
M16 Coxarthrosis [arthrosis of hip]	0.998	0.002	0.000
M16.9 Coxarthrosis, unspecified	0.998	0.002	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003	0.000
L03.1 Cellulitis of other parts of limb	0.997	0.003	0.000
I83 Varicose veins of lower extremities	0.996	0.004	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.996	0.004	0.000
E70-E90 Metabolic disorders	0.996	0.004	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.996	0.004	0.000
E83 Disorders of mineral metabolism	0.995	0.005	0.000
I10-I15 Hypertensive diseases	0.994	0.006	0.000
I10 Essential (primary) hypertension	0.993	0.007	0.000
M19 Other arthrosis	0.993	0.007	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.992	0.008	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.991	0.009	0.000
K76.6 Portal hypertension	0.991	0.009	0.000
K74.0 Hepatic fibrosis	0.990	0.010	0.000
M86-M90 Other osteopathies	0.984	0.016	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.982	0.018	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.970	0.020	0.010
Chapter XI Diseases of the digestive system	0.980	0.020	0.000
E10-E14 Diabetes mellitus	0.975	0.025	0.000
I85 Oesophageal varices	0.974	0.026	0.000
Chapter II Neoplasms	0.973	0.027	0.000
Chapter VIII Diseases of the ear and mastoid process	0.971	0.029	0.000
M19.0 Primary arthrosis of other joints	0.971	0.029	0.000
L20-L30 Dermatitis and eczema	0.970	0.030	0.000
Chapter XX External causes of morbidity and mortality	0.967	0.033	0.000
E11 Non-insulin-dependent diabetes mellitus	0.965	0.035	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.961	0.035	0.004
L30 Other dermatitis	0.964	0.036	0.000
D75 Other diseases of blood and blood-forming organs	0.961	0.038	0.001
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.960	0.040	0.000
E11.9 Without complications	0.959	0.041	0.000
L30.9 Dermatitis, unspecified	0.959	0.041	0.000
S60-S69 Injuries to the wrist and hand	0.958	0.042	0.000
D75.1 Secondary polycythaemia	0.958	0.042	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.956	0.044	0.000
I85.9 Oesophageal varices without bleeding	0.954	0.046	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.953	0.047	0.000
G40-G47 Episodic and paroxysmal disorders	0.952	0.048	0.000
M80-M85 Disorders of bone density and structure	0.952	0.048	0.000
M05-M14 Inflammatory polyarthropathies	0.951	0.049	0.000
I86 Varicose veins of other sites	0.950	0.050	0.000
I80 Phlebitis and thrombophlebitis	0.948	0.052	0.000
G40 Epilepsy	0.945	0.055	0.000
T51 Toxic effect of alcohol	0.945	0.055	0.000
G37 Other demyelinating diseases of central nervous system	0.945	0.055	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.939	0.061	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.937	0.063	0.000
T51.0 Ethanol	0.937	0.063	0.000
K70 Alcoholic liver disease	0.931	0.069	0.000
M87 Osteonecrosis	0.928	0.072	0.000
S00-S09 Injuries to the head	0.920	0.080	0.000
E80.1 Porphyria cutanea tarda	0.920	0.080	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.916	0.084	0.000
K50-K52 Noninfective enteritis and colitis	0.915	0.085	0.000
M84 Disorders of continuity of bone	0.912	0.088	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.909	0.091	0.000
L03.8 Cellulitis of other sites	0.909	0.091	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.908	0.092	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.908	0.092	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.905	0.093	0.002
K51 Ulcerative colitis	0.906	0.094	0.000
T66-T78 Other and unspecified effects of external causes	0.904	0.096	0.000
M86 Osteomyelitis	0.904	0.096	0.000
S06 Intracranial injury	0.903	0.097	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.901	0.099	0.000
M13 Other arthritis	0.898	0.102	0.000
M40-M43 Deforming dorsopathies	0.894	0.106	0.000
T90 Sequelae of injuries of head	0.893	0.107	0.000
M19.9 Arthrosis, unspecified	0.893	0.107	0.000
M87.9 Osteonecrosis, unspecified	0.892	0.108	0.000
C15-C26 Malignant neoplasms of digestive organs	0.890	0.110	0.000
W00-W19 Falls	0.887	0.113	0.000
K76.9 Liver disease, unspecified	0.882	0.118	0.000
M16.1 Other primary coxarthrosis	0.879	0.121	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.878	0.122	0.000
M89 Other disorders of bone	0.877	0.123	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.877	0.123	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.877	0.123	0.000
M50-M54 Other dorsopathies	0.876	0.124	0.000
H65-H75 Diseases of middle ear and mastoid	0.874	0.126	0.000
M13.9 Arthritis, unspecified	0.874	0.126	0.000
G70-G73 Diseases of myoneural junction and muscle	0.873	0.127	0.000
G30-G32 Other degenerative diseases of the nervous system	0.873	0.127	0.000
M10 Gout	0.872	0.128	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.870	0.130	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.868	0.132	0.000
G40.9 Epilepsy, unspecified	0.864	0.136	0.000
W20-W49 Exposure to inanimate mechanical forces	0.864	0.136	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.860	0.140	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.859	0.141	0.000
H60-H62 Diseases of external ear	0.856	0.144	0.000
H90-H95 Other disorders of ear	0.856	0.144	0.000
W19 Unspecified fall	0.854	0.146	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.854	0.146	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.852	0.148	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.851	0.149	0.000
S10-S19 Injuries to the neck	0.849	0.151	0.000
L03.0 Cellulitis of finger and toe	0.849	0.151	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.847	0.153	0.000
W19.4 Street and highway	0.847	0.153	0.000
L50-L54 Urticaria and erythema	0.847	0.153	0.000
L03.2 Cellulitis of face	0.846	0.154	0.000
D46 Myelodysplastic syndromes	0.845	0.155	0.000
C25 Malignant neoplasm of pancreas	0.842	0.158	0.000
S61 Open wound of wrist and hand	0.841	0.159	0.000
M84.4 Pathological fracture, not elsewhere classified	0.841	0.159	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.840	0.160	0.000
M86.9 Osteomyelitis, unspecified	0.839	0.161	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.835	0.165	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.835	0.165	0.000
I86.8 Varicose veins of other specified sites	0.834	0.166	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.832	0.168	0.000
K51.9 Ulcerative colitis, unspecified	0.830	0.170	0.000
M50 Cervical disk disorders	0.830	0.170	0.000
C22.0 Liver cell carcinoma	0.829	0.171	0.000
E11.5 With peripheral circulatory complications	0.829	0.171	0.000
M65-M68 Disorders of synovium and tendon	0.824	0.176	0.000
I86.1 Scrotal varices	0.823	0.176	0.000
I87 Other disorders of veins	0.823	0.177	0.000
T78 Adverse effects, not elsewhere classified	0.823	0.177	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.821	0.179	0.000
T90.9 Sequelae of unspecified injury of head	0.821	0.179	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.820	0.180	0.000
C64-C68 Malignant neoplasms of urinary tract	0.817	0.183	0.000
S90-S99 Injuries to the ankle and foot	0.817	0.183	0.000
E89.0 Postprocedural hypothyroidism	0.817	0.183	0.000
S62 Fracture at wrist and hand level	0.816	0.184	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.814	0.186	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.813	0.187	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.810	0.190	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.808	0.192	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.806	0.194	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.806	0.194	0.000
M10.9 Gout, unspecified	0.806	0.194	0.000
M00-M03 Infectious arthropathies	0.805	0.195	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.805	0.195	0.000
M41 Scoliosis	0.805	0.195	0.000
K70.3 Alcoholic cirrhosis of liver	0.804	0.196	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.803	0.197	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.803	0.197	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.803	0.197	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.800	0.200	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.800	0.200	0.000
S06.3 Focal brain injury	0.797	0.203	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.795	0.204	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.792	0.208	0.000
S68 Traumatic amputation of wrist and hand	0.792	0.208	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.791	0.209	0.000
T00-T07 Injuries involving multiple body regions	0.790	0.210	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.790	0.210	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.790	0.210	0.000
M19.2 Other secondary arthrosis	0.788	0.212	0.000
M11 Other crystal arthropathies	0.787	0.213	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.786	0.214	0.000
H66 Suppurative and unspecified otitis media	0.785	0.215	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.784	0.216	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.784	0.216	0.000
S06.4 Epidural haemorrhage	0.783	0.217	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.783	0.217	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.783	0.217	0.000
G30 Alzheimer's disease	0.782	0.218	0.000
C25.9 Pancreas, unspecified	0.782	0.218	0.000
M19.98 Arthrosis, unspecified (Other)	0.780	0.220	0.000
D69 Purpura and other haemorrhagic conditions	0.779	0.221	0.001
S06.2 Diffuse brain injury	0.779	0.221	0.000
M84.0 Malunion of fracture	0.779	0.221	0.000
M84.8 Other disorders of continuity of bone	0.778	0.222	0.000
M50.1 Cervical disk disorder with radiculopathy	0.778	0.222	0.000
I86.4 Gastric varices	0.778	0.222	0.000
M89.0 Algoneurodystrophy	0.778	0.222	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.778	0.222	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.777	0.222	0.000
K51.2 Ulcerative (chronic) proctitis	0.776	0.224	0.000
K70.4 Alcoholic hepatic failure	0.775	0.225	0.000
D66 Hereditary factor VIII deficiency	0.774	0.225	0.001
M45-M49 Spondylopathies	0.774	0.226	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.774	0.226	0.000
M85 Other disorders of bone density and structure	0.774	0.226	0.000
X50-X57 Overexertion, travel and privation	0.771	0.229	0.000
H93 Other disorders of ear, not elsewhere classified	0.771	0.229	0.000
M10.99 Gout, unspecified (Site unspecified)	0.771	0.229	0.000
M16.5 Other posttraumatic coxarthrosis	0.770	0.230	0.000
S62.6 Fracture of other finger	0.770	0.230	0.000
M60-M63 Disorders of muscles	0.770	0.230	0.000
W29 Contact with other powered hand tools and household machinery	0.769	0.231	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.768	0.232	0.000
K76.7 Hepatorenal syndrome	0.768	0.232	0.000
G90-G99 Other disorders of the nervous system	0.766	0.234	0.000
M50.3 Other cervical disk degeneration	0.766	0.234	0.000
H61 Other disorders of external ear	0.764	0.236	0.000
E89.3 Postprocedural hypopituitarism	0.762	0.238	0.000
M66 Spontaneous rupture of synovium and tendon	0.761	0.239	0.000
D44.6 Carotid body	0.761	0.239	0.000
G71 Primary disorders of muscles	0.758	0.242	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.757	0.242	0.000
M83 Adult osteomalacia	0.757	0.243	0.000
S67 Crushing injury of wrist and hand	0.757	0.243	0.000
X10-X19 Contact with heat and hot substances	0.756	0.244	0.000
V40-V49 Car occupant injured in transport accident	0.754	0.246	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.752	0.248	0.000
T78.4 Allergy, unspecified	0.752	0.248	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.751	0.249	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.750	0.250	0.000
K70.0 Alcoholic fatty liver	0.750	0.250	0.000
M19.1 Posttraumatic arthrosis of other joints	0.749	0.250	0.000
D48.6 Breast	0.749	0.251	0.000
K51.5 Mucosal proctocolitis	0.749	0.251	0.000
S09 Other and unspecified injuries of head	0.748	0.252	0.000
E80.4 Gilbert's syndrome	0.748	0.252	0.000
E85 Amyloidosis	0.746	0.254	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.746	0.254	0.000
V70-V79 Bus occupant injured in transport accident	0.746	0.254	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.745	0.255	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.742	0.258	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.742	0.258	0.000
Chapter V Mental and behavioural disorders	0.742	0.258	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.740	0.260	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.740	0.260	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.739	0.261	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.738	0.262	0.000
G03 Meningitis due to other and unspecified causes	0.738	0.262	0.000
L40-L45 Papulosquamous disorders	0.738	0.262	0.000
E11.2 With renal complications	0.737	0.263	0.000
C73 Malignant neoplasm of thyroid gland	0.737	0.263	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.736	0.264	0.000
S62.61 Fracture of other finger (open)	0.736	0.264	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.736	0.264	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.735	0.265	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.734	0.266	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.733	0.267	0.000
V80-V89 Other land transport accidents	0.731	0.269	0.000
E14 Unspecified diabetes mellitus	0.730	0.270	0.000
E11.4 With neurological complications	0.730	0.270	0.000
W19.1 Residential institution	0.730	0.270	0.000
M82 Osteoporosis in diseases classified elsewhere	0.728	0.272	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.727	0.273	0.000
C21 Malignant neoplasm of anus and anal canal	0.727	0.273	0.000
E40-E46 Malnutrition	0.727	0.273	0.000
H74 Other disorders of middle ear and mastoid	0.727	0.273	0.000
H73 Other disorders of tympanic membrane	0.725	0.275	0.000
W50-W64 Exposure to animate mechanical forces	0.724	0.276	0.000
R79 Other abnormal findings of blood chemistry	0.724	0.276	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.723	0.277	0.000
R79.0 Abnormal level of blood mineral	0.722	0.278	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.722	0.278	0.000
M16.3 Other dysplastic coxarthrosis	0.721	0.279	0.000
T79-T79 Certain early complications of trauma	0.721	0.279	0.000
L30.8 Other specified dermatitis	0.721	0.279	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.720	0.280	0.000
R47-R49 Symptoms and signs involving speech and voice	0.719	0.281	0.000
D68 Other coagulation defects	0.719	0.281	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.719	0.281	0.000
G20-G26 Extrapyramidal and movement disorders	0.718	0.282	0.000
K51.8 Other ulcerative colitis	0.718	0.282	0.000
M41.9 Scoliosis, unspecified	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
K77 Liver disorders in diseases classified elsewhere	0.717	0.283	0.000
K71 Toxic liver disease	0.717	0.283	0.000
L10-L14 Bullous disorders	0.717	0.283	0.000
K74.4 Secondary biliary cirrhosis	0.717	0.283	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.717	0.283	0.000
K74.1 Hepatic sclerosis	0.717	0.283	0.000
K76.5 Hepatic veno-occlusive disease	0.717	0.283	0.000
K76.4 Peliosis hepatis	0.717	0.283	0.000
K76.3 Infarction of liver	0.717	0.283	0.000
K76.2 Central haemorrhagic necrosis of liver	0.717	0.283	0.000
K76.1 Chronic passive congestion of liver	0.717	0.283	0.000
L04 Acute lymphadenitis	0.717	0.283	0.000
L01 Impetigo	0.717	0.283	0.000
L00 Staphylococcal scalded skin syndrome	0.717	0.283	0.000
G36 Other acute disseminated demyelination	0.717	0.283	0.000
I88 Nonspecific lymphadenitis	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.716	0.284	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.716	0.284	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.716	0.284	0.000
G40.5 Special epileptic syndromes	0.716	0.284	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285	0.000
S65 Injury of blood vessels at wrist and hand level	0.715	0.285	0.000
D64.9 Anaemia, unspecified	0.000	0.286	0.714
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.714	0.286	0.000
I85.0 Oesophageal varices with bleeding	0.714	0.286	0.000
E84 Cystic fibrosis	0.714	0.286	0.000
E79 Disorders of purine and pyrimidine metabolism	0.714	0.286	0.000
E77 Disorders of glycoprotein metabolism	0.714	0.286	0.000
E76 Disorders of glycosaminoglycan metabolism	0.714	0.286	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.714	0.286	0.000
E72 Other disorders of amino-acid metabolism	0.714	0.286	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.714	0.286	0.000
E70 Disorders of aromatic amino-acid metabolism	0.714	0.286	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.714	0.286	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.714	0.286	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.713	0.286	0.000
E83.8 Other disorders of mineral metabolism	0.713	0.286	0.000
E83.2 Disorders of zinc metabolism	0.713	0.286	0.000
E83.0 Disorders of copper metabolism	0.713	0.286	0.000
E11.1 With ketoacidosis	0.713	0.287	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.713	0.287	0.000
S02 Fracture of skull and facial bones	0.713	0.287	0.000
I13 Hypertensive heart and renal disease	0.712	0.287	0.000
M19.8 Other specified arthrosis	0.712	0.288	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.708	0.288	0.003
M14 Arthropathies in other diseases classified elsewhere	0.711	0.289	0.000
M89.3 Hypertrophy of bone	0.711	0.289	0.000
T33-T35 Frostbite	0.711	0.289	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289	0.000
I05-I09 Chronic rheumatic heart diseases	0.710	0.290	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.710	0.290	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.709	0.291	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.708	0.292	0.000
D69.6 Thrombocytopenia, unspecified	0.708	0.292	0.000
S64 Injury of nerves at wrist and hand level	0.707	0.293	0.000
R73 Elevated blood glucose level	0.707	0.293	0.000
H70 Mastoiditis and related conditions	0.706	0.294	0.000
M13.1 Monoarthritis, not elsewhere classified	0.706	0.294	0.000
Y00-Y09 Assault	0.705	0.295	0.000
S06.8 Other intracranial injuries	0.705	0.295	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.705	0.295	0.000
L03.3 Cellulitis of trunk	0.705	0.295	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.704	0.296	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.704	0.296	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.704	0.296	0.000
E73 Lactose intolerance	0.702	0.298	0.000
L28 Lichen simplex chronicus and prurigo	0.702	0.298	0.000
D55-D59 Haemolytic anaemias	0.695	0.298	0.007
G41 Status epilepticus	0.702	0.298	0.000
W29.9 Unspecified place	0.702	0.298	0.000
S61.1 Open wound of finger(s) with damage to nail	0.701	0.299	0.000
L60-L75 Disorders of skin appendages	0.701	0.299	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.700	0.300	0.000
L53 Other erythematous conditions	0.700	0.300	0.000
M40 Kyphosis and lordosis	0.700	0.300	0.000
E12 Malnutrition-related diabetes mellitus	0.699	0.301	0.000
S90 Superficial injury of ankle and foot	0.699	0.301	0.000
W17 Other fall from one level to another	0.698	0.302	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.698	0.302	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.698	0.302	0.000
E89.2 Postprocedural hypoparathyroidism	0.698	0.302	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.697	0.303	0.000
C25.3 Pancreatic duct	0.697	0.303	0.000
K76.8 Other specified diseases of liver	0.697	0.303	0.000
M19.08 Primary arthrosis of other joints (Other)	0.696	0.304	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.696	0.304	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.696	0.304	0.000
M13.93 Arthritis, unspecified (Forearm)	0.696	0.304	0.000
D72 Other disorders of white blood cells	0.693	0.305	0.003
L25 Unspecified contact dermatitis	0.695	0.305	0.000
L24 Irritant contact dermatitis	0.695	0.305	0.000
L23 Allergic contact dermatitis	0.695	0.305	0.000
L26 Exfoliative dermatitis	0.695	0.305	0.000
L22 Diaper [napkin] dermatitis	0.695	0.305	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.695	0.305	0.000
W22 Striking against or struck by other objects	0.695	0.305	0.000
S12 Fracture of neck	0.695	0.305	0.000
Q80-Q89 Other congenital malformations	0.695	0.305	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.694	0.306	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.693	0.307	0.000
Y35-Y36 Legal intervention and operations of war	0.693	0.307	0.000
Y10-Y34 Event of undetermined intent	0.693	0.307	0.000
X85-X99 Assault	0.693	0.307	0.000
X30-X39 Exposure to forces of nature	0.693	0.307	0.000
X00-X09 Exposure to smoke, fire and flames	0.693	0.307	0.000
W75-W84 Other accidental threats to breathing	0.693	0.307	0.000
W65-W74 Accidental drowning and submersion	0.693	0.307	0.000
V98-V99 Other and unspecified transport accidents	0.693	0.307	0.000
V95-V97 Air and space transport accidents	0.693	0.307	0.000
V90-V94 Water transport accidents	0.693	0.307	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.693	0.307	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.693	0.307	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.693	0.307	0.000
V01-V09 Pedestrian injured in transport accident	0.693	0.307	0.000
M66.0 Rupture of popliteal cyst	0.693	0.307	0.000
M54 Dorsalgia	0.693	0.307	0.000
E11.7 With multiple complications	0.692	0.308	0.000
D74 Methaemoglobinaemia	0.689	0.308	0.003
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.689	0.308	0.003
D71 Functional disorders of polymorphonuclear neutrophils	0.689	0.308	0.003
T91 Sequelae of injuries of neck and trunk	0.692	0.308	0.000
K73 Chronic hepatitis, not elsewhere classified	0.691	0.309	0.000
L30.5 Pityriasis alba	0.691	0.309	0.000
L30.4 Erythema intertrigo	0.691	0.309	0.000
L30.3 Infective dermatitis	0.691	0.309	0.000
L30.2 Cutaneous autosensitisation	0.691	0.309	0.000
L30.1 Dyshidrosis [pompholyx]	0.691	0.309	0.000
L30.0 Nummular dermatitis	0.691	0.309	0.000
X60-X84 Intentional self-harm	0.690	0.310	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.690	0.310	0.000
D75.0 Familial erythrocytosis	0.689	0.310	0.001
T65 Toxic effect of other and unspecified substances	0.688	0.311	0.000
T62 Toxic effect of other noxious substances eaten as food	0.688	0.311	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.688	0.311	0.000
T60 Toxic effect of pesticides	0.688	0.311	0.000
T57 Toxic effect of other inorganic substances	0.688	0.311	0.000
T56 Toxic effect of metals	0.688	0.311	0.000
T54 Toxic effect of corrosive substances	0.688	0.311	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.688	0.311	0.000
T52 Toxic effect of organic solvents	0.688	0.311	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.688	0.311	0.000
T58 Toxic effect of carbon monoxide	0.688	0.311	0.000
T55 Toxic effect of soaps and detergents	0.688	0.311	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.688	0.312	0.000
T70 Effects of air pressure and water pressure	0.688	0.312	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.687	0.312	0.000
X59 Exposure to unspecified factor	0.687	0.313	0.000
L51 Erythema multiforme	0.687	0.313	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.686	0.313	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.685	0.314	0.000
E80.6 Other disorders of bilirubin metabolism	0.685	0.314	0.000
E80.5 Crigler-Najjar syndrome	0.685	0.314	0.000
E80.3 Defects of catalase and peroxydase	0.685	0.314	0.000
E80.2 Other porphyria	0.685	0.314	0.000
E80.0 Hereditary erythropoietic porphyria	0.685	0.314	0.000
G44 Other headache syndromes	0.685	0.315	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.684	0.316	0.001
G91 Hydrocephalus	0.684	0.316	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.683	0.317	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.683	0.317	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.683	0.317	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.682	0.318	0.000
T17 Foreign body in respiratory tract	0.682	0.318	0.000
M12 Other specific arthropathies	0.682	0.318	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.682	0.318	0.000
M08 Juvenile arthritis	0.682	0.318	0.000
I86.3 Vulval varices	0.681	0.318	0.000
I86.2 Pelvic varices	0.681	0.318	0.000
I86.0 Sublingual varices	0.681	0.318	0.000
E74 Other disorders of carbohydrate metabolism	0.681	0.318	0.000
K74.3 Primary biliary cirrhosis	0.681	0.318	0.000
G30.0 Alzheimer's disease with early onset	0.681	0.319	0.000
D46.2 Refractory anaemia with excess of blasts	0.680	0.320	0.000
G00 Bacterial meningitis, not elsewhere classified	0.679	0.321	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.678	0.322	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.678	0.322	0.000
T51.8 Other alcohols	0.677	0.322	0.000
T51.3 Fusel oil	0.677	0.322	0.000
T51.2 2-Propanol	0.677	0.322	0.000
T51.1 Methanol	0.677	0.322	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.677	0.323	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.677	0.323	0.000
G37.5 Concentric sclerosis [Balo]	0.677	0.323	0.000
G37.4 Subacute necrotising myelitis	0.677	0.323	0.000
G37.2 Central pontine myelinolysis	0.677	0.323	0.000
G37.1 Central demyelination of corpus callosum	0.677	0.323	0.000
G37.0 Diffuse sclerosis	0.677	0.323	0.000
Chapter XXI Factors influencing health status and contact with health services	0.677	0.323	0.000
C23 Malignant neoplasm of gallbladder	0.677	0.323	0.000
K74.5 Biliary cirrhosis, unspecified	0.677	0.323	0.000
M86.6 Other chronic osteomyelitis	0.677	0.323	0.000
M47 Spondylosis	0.677	0.323	0.000
C25.2 Tail of pancreas	0.676	0.324	0.000
E11.8 With unspecified complications	0.675	0.324	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.675	0.325	0.000
M84.03 Malunion of fracture (Forearm)	0.675	0.325	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.675	0.325	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.675	0.325	0.000
L42 Pityriasis rosea	0.673	0.327	0.000
L20 Atopic dermatitis	0.672	0.327	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.672	0.328	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.672	0.328	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.672	0.328	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.672	0.328	0.000
E89.5 Postprocedural testicular hypofunction	0.672	0.328	0.000
E89.4 Postprocedural ovarian failure	0.672	0.328	0.000
E89.1 Postprocedural hypoinsulinaemia	0.672	0.328	0.000
R49 Voice disturbances	0.672	0.328	0.000
T68 Hypothermia	0.672	0.328	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.671	0.329	0.000
S62.3 Fracture of other metacarpal bone	0.671	0.329	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.671	0.329	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.670	0.330	0.000
M11.2 Other chondrocalcinosis	0.670	0.330	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.670	0.330	0.000
Z72 Problems related to lifestyle	0.669	0.331	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.669	0.331	0.000
V10-V19 Pedal cyclist injured in transport accident	0.668	0.331	0.000
W20 Struck by thrown, projected or falling object	0.667	0.333	0.000
H61.2 Impacted cerumen	0.666	0.334	0.000
H66.4 Suppurative otitis media, unspecified	0.666	0.334	0.000
M87.8 Other osteonecrosis	0.665	0.335	0.000
M87.3 Other secondary osteonecrosis	0.665	0.335	0.000
M87.1 Osteonecrosis due to drugs	0.665	0.335	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations