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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs191110399
log Bayes Factor = 1.08712
Chromosome 11   position 127,347,811  (GRCh37) Explore rs191110399 on Ensembl!
Variant rs191110399 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.916 0.084 0.000
Chapter XX External causes of morbidity and mortality
0.910 0.090 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.901 0.099 0.000
Chapter IX Diseases of the circulatory system
0.896 0.104 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.893 0.107 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.884 0.116 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.873 0.127 0.000
I30-I52 Other forms of heart disease
0.872 0.128 0.000
Chapter II Neoplasms
0.863 0.137 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.839 0.161 0.000
I50 Heart failure
0.817 0.183 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.803 0.197 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.801 0.199 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.780 0.220 0.000
I20-I25 Ischaemic heart diseases
0.779 0.221 0.000
D50-D53 Nutritional anaemias
0.774 0.226 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.772 0.228 0.000
Chapter I Certain infectious and parasitic diseases
0.766 0.233 0.000
Chapter XI Diseases of the digestive system
0.750 0.250 0.000
Y83.4 Other reconstructive surgery
0.749 0.251 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.747 0.253 0.000
Chapter VIII Diseases of the ear and mastoid process
0.745 0.255 0.000
I34 Nonrheumatic mitral valve disorders
0.745 0.255 0.000
D70 Agranulocytosis
0.744 0.256 0.000
I51 Complications and ill-defined descriptions of heart disease
0.743 0.257 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.734 0.265 0.000
I44 Atrioventricular and left bundle-branch block
0.734 0.266 0.000
I60-I69 Cerebrovascular diseases
0.733 0.267 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.726 0.274 0.000
Y83.8 Other surgical procedures
0.726 0.274 0.000
Y83.9 Surgical procedure, unspecified
0.724 0.275 0.000
C60-C63 Malignant neoplasms of male genital organs
0.718 0.282 0.000
I50.1 Left ventricular failure
0.717 0.283 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.714 0.286 0.000
K55-K64 Other diseases of intestines
0.712 0.288 0.000
E00-E07 Disorders of thyroid gland
0.710 0.290 0.000
D60-D64 Aplastic and other anaemias
0.708 0.292 0.000
Chapter XIV Diseases of the genitourinary system
0.707 0.293 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.706 0.294 0.000
K62 Other diseases of anus and rectum
0.702 0.298 0.000
I25 Chronic ischaemic heart disease
0.699 0.301 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.696 0.304 0.000
D50 Iron deficiency anaemia
0.695 0.305 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.694 0.305 0.000
I50.9 Heart failure, unspecified
0.687 0.313 0.000
L60-L75 Disorders of skin appendages
0.687 0.313 0.000
I05-I09 Chronic rheumatic heart diseases
0.684 0.316 0.000
K62.1 Rectal polyp
0.681 0.319 0.000
Y86 Sequelae of other accidents
0.673 0.327 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.662 0.338 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.662 0.338 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.660 0.340 0.000
L03 Cellulitis
0.657 0.343 0.000
Chapter XXII Codes for special purposes
0.657 0.343 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.657 0.343 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.657 0.343 0.000
I31 Other diseases of pericardium
0.656 0.344 0.000
I50.0 Congestive heart failure
0.652 0.348 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.652 0.348 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.652 0.348 0.000
Y35-Y36 Legal intervention and operations of war
0.652 0.348 0.000
Y10-Y34 Event of undetermined intent
0.652 0.348 0.000
Y00-Y09 Assault
0.652 0.348 0.000
X85-X99 Assault
0.652 0.348 0.000
X60-X84 Intentional self-harm
0.652 0.348 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.652 0.348 0.000
X50-X57 Overexertion, travel and privation
0.652 0.348 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.652 0.348 0.000
X30-X39 Exposure to forces of nature
0.652 0.348 0.000
X20-X29 Contact with venomous animals and plants
0.652 0.348 0.000
X10-X19 Contact with heat and hot substances
0.652 0.348 0.000
X00-X09 Exposure to smoke, fire and flames
0.652 0.348 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.652 0.348 0.000
W75-W84 Other accidental threats to breathing
0.652 0.348 0.000
W65-W74 Accidental drowning and submersion
0.652 0.348 0.000
W50-W64 Exposure to animate mechanical forces
0.652 0.348 0.000
W20-W49 Exposure to inanimate mechanical forces
0.652 0.348 0.000
V98-V99 Other and unspecified transport accidents
0.652 0.348 0.000
V95-V97 Air and space transport accidents
0.652 0.348 0.000
V90-V94 Water transport accidents
0.652 0.348 0.000
V80-V89 Other land transport accidents
0.652 0.348 0.000
V70-V79 Bus occupant injured in transport accident
0.652 0.348 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.652 0.348 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.652 0.348 0.000
V40-V49 Car occupant injured in transport accident
0.652 0.348 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.652 0.348 0.000
V20-V29 Motorcycle rider injured in transport accident
0.652 0.348 0.000
V10-V19 Pedal cyclist injured in transport accident
0.652 0.348 0.000
V01-V09 Pedestrian injured in transport accident
0.652 0.348 0.000
Chapter VI Diseases of the nervous system
0.652 0.348 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.648 0.351 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.648 0.352 0.000
I46 Cardiac arrest
0.647 0.353 0.000
D10-D36 Benign neoplasms
0.645 0.355 0.000
C64-C68 Malignant neoplasms of urinary tract
0.645 0.355 0.000
I00-I02 Acute rheumatic fever
0.642 0.358 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.642 0.358 0.000
K40-K46 Hernia
0.641 0.359 0.000
Y83.5 Amputation of limb(s)
0.640 0.360 0.000
Y83.3 Surgical operation with formation of external stoma
0.640 0.360 0.000
Y83.0 Surgical operation with transplant of whole organ
0.640 0.360 0.000
A00-A09 Intestinal infectious diseases
0.640 0.360 0.000
D00-D09 In situ neoplasms
0.639 0.361 0.000
Chapter X Diseases of the respiratory system
0.639 0.361 0.000
E50-E64 Other nutritional deficiencies
0.638 0.362 0.000
I42 Cardiomyopathy
0.636 0.364 0.000
I22 Subsequent myocardial infarction
0.634 0.366 0.000
I24 Other acute ischaemic heart diseases
0.634 0.366 0.000
D80-D89 Certain disorders involving the immune mechanism
0.634 0.366 0.000
D55-D59 Haemolytic anaemias
0.634 0.366 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.634 0.366 0.000
L40-L45 Papulosquamous disorders
0.634 0.366 0.000
S80-S89 Injuries to the knee and lower leg
0.631 0.369 0.000
I52 Other heart disorders in diseases classified elsewhere
0.625 0.374 0.000
I49 Other cardiac arrhythmias
0.625 0.374 0.000
I48 Atrial fibrillation and flutter
0.625 0.374 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.625 0.374 0.000
I41 Myocarditis in diseases classified elsewhere
0.625 0.374 0.000
I40 Acute myocarditis
0.625 0.374 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.625 0.374 0.000
I37 Pulmonary valve disorders
0.625 0.374 0.000
I36 Nonrheumatic tricuspid valve disorders
0.625 0.374 0.000
I33 Acute and subacute endocarditis
0.625 0.374 0.000
I32 Pericarditis in diseases classified elsewhere
0.625 0.374 0.000
I30 Acute pericarditis
0.625 0.374 0.000
I38 Endocarditis, valve unspecified
0.625 0.374 0.000
I51.8 Other ill-defined heart diseases
0.622 0.378 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.620 0.380 0.000
L50-L54 Urticaria and erythema
0.620 0.380 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.619 0.381 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.619 0.381 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.619 0.381 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.619 0.381 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.619 0.381 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.619 0.381 0.000
I34.0 Mitral (valve) insufficiency
0.618 0.382 0.000
I44.7 Left bundle-branch block, unspecified
0.618 0.382 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.618 0.382 0.000
S60-S69 Injuries to the wrist and hand
0.617 0.383 0.000
H65-H75 Diseases of middle ear and mastoid
0.617 0.383 0.000
W00-W19 Falls
0.615 0.385 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.615 0.385 0.000
E04 Other non-toxic goitre
0.614 0.386 0.000
C61 Malignant neoplasm of prostate
0.614 0.386 0.000
S50-S59 Injuries to the elbow and forearm
0.613 0.387 0.000
A30-A49 Other bacterial diseases
0.612 0.388 0.000
C34 Malignant neoplasm of bronchus and lung
0.606 0.394 0.000
D50.8 Other iron deficiency anaemias
0.606 0.394 0.000
K35-K38 Diseases of appendix
0.603 0.397 0.000
L20-L30 Dermatitis and eczema
0.601 0.398 0.000
L10-L14 Bullous disorders
0.601 0.398 0.000
E20-E35 Disorders of other endocrine glands
0.601 0.399 0.000
C51-C58 Malignant neoplasms of female genital organs
0.599 0.401 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.596 0.404 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.595 0.405 0.000
D12.6 Colon, unspecified
0.593 0.407 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.592 0.408 0.000
I34.1 Mitral (valve) prolapse
0.592 0.408 0.000
I26 Pulmonary embolism
0.590 0.409 0.000
K62.6 Ulcer of anus and rectum
0.589 0.411 0.000
K43 Ventral hernia
0.589 0.411 0.000
I25.2 Old myocardial infarction
0.586 0.414 0.000
B25-B34 Other viral diseases
0.581 0.419 0.000
I51.7 Cardiomegaly
0.581 0.419 0.000
K62.5 Haemorrhage of anus and rectum
0.579 0.421 0.000
S70-S79 Injuries to the hip and thigh
0.579 0.421 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.577 0.423 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.576 0.423 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.576 0.424 0.000
D75 Other diseases of blood and blood-forming organs
0.576 0.424 0.000
D74 Methaemoglobinaemia
0.576 0.424 0.000
D73 Diseases of spleen
0.576 0.424 0.000
D72 Other disorders of white blood cells
0.576 0.424 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.576 0.424 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.576 0.424 0.000
S40-S49 Injuries to the shoulder and upper arm
0.576 0.424 0.000
I67 Other cerebrovascular diseases
0.575 0.425 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.574 0.425 0.000
T79-T79 Certain early complications of trauma
0.574 0.425 0.000
T66-T78 Other and unspecified effects of external causes
0.574 0.425 0.000
T33-T35 Frostbite
0.574 0.425 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.574 0.425 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.574 0.425 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.574 0.425 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.574 0.425 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.574 0.425 0.000
T00-T07 Injuries involving multiple body regions
0.574 0.425 0.000
S90-S99 Injuries to the ankle and foot
0.574 0.425 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.574 0.425 0.000
S20-S29 Injuries to the thorax
0.574 0.425 0.000
S10-S19 Injuries to the neck
0.574 0.425 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.573 0.427 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.572 0.427 0.000
D50.9 Iron deficiency anaemia, unspecified
0.570 0.430 0.000
I27 Other pulmonary heart diseases
0.568 0.432 0.000
K58 Irritable bowel syndrome
0.566 0.433 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.566 0.434 0.000
Y84.8 Other medical procedures
0.565 0.434 0.000
C77.1 Intrathoracic lymph nodes
0.565 0.435 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.565 0.435 0.000
I45 Other conduction disorders
0.564 0.436 0.000
S00-S09 Injuries to the head
0.563 0.437 0.000
E40-E46 Malnutrition
0.559 0.441 0.000
I23 Certain current complications following acute myocardial infarction
0.558 0.442 0.000
H90-H95 Other disorders of ear
0.558 0.442 0.000
D64 Other anaemias
0.557 0.443 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.557 0.443 0.000
E03 Other hypothyroidism
0.557 0.443 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.557 0.443 0.000
D53 Other nutritional anaemias
0.555 0.445 0.000
D52 Folate deficiency anaemia
0.555 0.445 0.000
D51 Vitamin B12 deficiency anaemia
0.555 0.445 0.000
C15-C26 Malignant neoplasms of digestive organs
0.553 0.446 0.000
Y89 Sequelae of other external causes
0.553 0.447 0.000
Y88 Sequelae of surgical and medical care as external cause
0.553 0.447 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.553 0.447 0.000
Y85 Sequelae of transport accidents
0.553 0.447 0.000
N87 Dysplasia of cervix uteri
0.552 0.448 0.000
A04 Other bacterial intestinal infections
0.552 0.448 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.552 0.448 0.000
I44.0 Atrioventricular block, first degree
0.552 0.448 0.000
L03.9 Cellulitis, unspecified
0.551 0.449 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.550 0.450 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.550 0.450 0.000
B99-B99 Other infectious diseases
0.550 0.450 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.550 0.450 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.550 0.450 0.000
B65-B83 Helminthiases
0.550 0.450 0.000
B50-B64 Protozoal diseases
0.550 0.450 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.550 0.450 0.000
B15-B19 Viral hepatitis
0.550 0.450 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.550 0.450 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.550 0.450 0.000
A80-A89 Viral infections of the central nervous system
0.550 0.450 0.000
A75-A79 Rickettsioses
0.550 0.450 0.000
A70-A74 Other diseases caused by chlamydiae
0.550 0.450 0.000
A65-A69 Other spirochaetal diseases
0.550 0.450 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.550 0.450 0.000
A20-A28 Certain zoonotic bacterial diseases
0.550 0.450 0.000
A15-A19 Tuberculosis
0.550 0.450 0.000
N95 Menopausal and other perimenopausal disorders
0.547 0.453 0.000
I60 Subarachnoid haemorrhage
0.544 0.456 0.000
Y43 Primarily systemic agents
0.543 0.457 0.000
D61 Other aplastic anaemias
0.539 0.461 0.000
E53 Deficiency of other B group vitamins
0.536 0.464 0.000
N10-N16 Renal tubulo-interstitial diseases
0.536 0.464 0.000
C80 Malignant neoplasm without specification of site
0.535 0.464 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.535 0.464 0.000
H60-H62 Diseases of external ear
0.534 0.466 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.534 0.466 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.534 0.466 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.534 0.466 0.000
K62.3 Rectal prolapse
0.534 0.466 0.000
K63 Other diseases of intestine
0.534 0.466 0.000
I35 Nonrheumatic aortic valve disorders
0.533 0.467 0.000
I08 Multiple valve diseases
0.533 0.467 0.000
I51.9 Heart disease, unspecified
0.533 0.467 0.000
I51.6 Cardiovascular disease, unspecified
0.533 0.467 0.000
I51.5 Myocardial degeneration
0.533 0.467 0.000
I51.4 Myocarditis, unspecified
0.533 0.467 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.533 0.467 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.533 0.467 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.533 0.467 0.000
I51.0 Cardiac septal defect, acquired
0.533 0.467 0.000
L03.2 Cellulitis of face
0.532 0.467 0.000
I44.2 Atrioventricular block, complete
0.532 0.468 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.531 0.469 0.000
L60 Nail disorders
0.531 0.469 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.531 0.469 0.000
I24.8 Other forms of acute ischaemic heart disease
0.531 0.469 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.530 0.470 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.530 0.470 0.000
K90-K93 Other diseases of the digestive system
0.529 0.471 0.000
I69 Sequelae of cerebrovascular disease
0.528 0.472 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.528 0.472 0.000
I28 Other diseases of pulmonary vessels
0.527 0.473 0.000
I44.6 Other and unspecified fascicular block
0.526 0.474 0.000
I44.5 Left posterior fascicular block
0.526 0.474 0.000
I44.4 Left anterior fascicular block
0.526 0.474 0.000
I44.3 Other and unspecified atrioventricular block
0.526 0.474 0.000
I44.1 Atrioventricular block, second degree
0.526 0.474 0.000
C77.0 Lymph nodes of head, face and neck
0.526 0.474 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.526 0.474 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.526 0.474 0.000
I62 Other nontraumatic intracranial haemorrhage
0.526 0.474 0.000
I61 Intracerebral haemorrhage
0.526 0.474 0.000
J09-J18 Influenza and pneumonia
0.525 0.475 0.000
E04.2 Non-toxic multinodular goitre
0.523 0.476 0.000
G35 Multiple sclerosis
0.522 0.477 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.522 0.478 0.000
L05 Pilonidal cyst
0.521 0.479 0.000
L04 Acute lymphadenitis
0.521 0.479 0.000
L01 Impetigo
0.521 0.479 0.000
L00 Staphylococcal scalded skin syndrome
0.521 0.479 0.000
K50-K52 Noninfective enteritis and colitis
0.520 0.480 0.000
H80-H83 Diseases of inner ear
0.519 0.481 0.000
E65-E68 Obesity and other hyperalimentation
0.519 0.481 0.000
N20-N23 Urolithiasis
0.519 0.481 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.518 0.482 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.517 0.482 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.515 0.485 0.000
C62 Malignant neoplasm of testis
0.515 0.485 0.000
C60 Malignant neoplasm of penis
0.515 0.485 0.000
L03.3 Cellulitis of trunk
0.514 0.486 0.000
B35-B49 Mycoses
0.514 0.486 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.512 0.488 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.512 0.488 0.000
C32 Malignant neoplasm of larynx
0.512 0.488 0.000
C31 Malignant neoplasm of accessory sinuses
0.512 0.488 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.512 0.488 0.000
C37 Malignant neoplasm of thymus
0.512 0.488 0.000
C33 Malignant neoplasm of trachea
0.512 0.488 0.000
E70-E90 Metabolic disorders
0.511 0.489 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.511 0.489 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.511 0.489 0.000
K55 Vascular disorders of intestine
0.511 0.489 0.000
C77.3 Axillary and upper limb lymph nodes
0.511 0.489 0.000
E07 Other disorders of thyroid
0.509 0.491 0.000
E06 Thyroiditis
0.509 0.491 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.509 0.491 0.000
E00 Congenital iodine-deficiency syndrome
0.509 0.491 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.509 0.491 0.000
S82 Fracture of lower leg, including ankle
0.509 0.491 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.509 0.491 0.000
C91 Lymphoid leukaemia
0.508 0.491 0.000
C34.9 Bronchus or lung, unspecified
0.508 0.492 0.000
B95-B98 Bacterial, viral and other infectious agents
0.508 0.492 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.507 0.493 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.507 0.493 0.000
D62 Acute posthaemorrhagic anaemia
0.507 0.493 0.000
N99-N99 Other disorders of the genitourinary system
0.507 0.493 0.000
D12.0 Caecum
0.507 0.493 0.000
N84 Polyp of female genital tract
0.507 0.493 0.000
Y84.9 Medical procedure, unspecified
0.506 0.494 0.000
Y84.7 Blood-sampling
0.506 0.494 0.000
Y84.6 Urinary catheterisation
0.506 0.494 0.000
Y84.5 Insertion of gastric or duodenal sound
0.506 0.494 0.000
Y84.4 Aspiration of fluid
0.506 0.494 0.000
Y84.3 Shock therapy
0.506 0.494 0.000
Y84.2 Radiological procedure and radiotherapy
0.506 0.494 0.000
Y84.1 Kidney dialysis
0.506 0.494 0.000
Y84.0 Cardiac catheterisation
0.506 0.494 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.505 0.495 0.000
N00-N08 Glomerular diseases
0.505 0.495 0.000
C79 Secondary malignant neoplasm of other sites
0.505 0.495 0.000
K62.9 Disease of anus and rectum, unspecified
0.503 0.497 0.000
K62.7 Radiation proctitis
0.503 0.497 0.000
K62.4 Stenosis of anus and rectum
0.503 0.497 0.000
K62.2 Anal prolapse
0.503 0.497 0.000
C34.3 Lower lobe, bronchus or lung
0.503 0.497 0.000
N60-N64 Disorders of breast
0.503 0.497 0.000
I47 Paroxysmal tachycardia
0.502 0.497 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.502 0.498 0.000
C43 Malignant melanoma of skin
0.502 0.498 0.000
Y83.6 Removal of other organ (partial) (total)
0.501 0.498 0.000
I31.3 Pericardial effusion (noninflammatory)
0.501 0.499 0.000
I25.6 Silent myocardial ischaemia
0.501 0.499 0.000
I25.5 Ischaemic cardiomyopathy
0.501 0.499 0.000
I25.4 Coronary artery aneurysm
0.501 0.499 0.000
I25.3 Aneurysm of heart
0.501 0.499 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.501 0.499 0.000
A41 Other septicaemia
0.501 0.499 0.000
D69 Purpura and other haemorrhagic conditions
0.499 0.501 0.000
Y59 Other and unspecified vaccines and biological substances
0.499 0.501 0.000
Y58 Bacterial vaccines
0.499 0.501 0.000
Y57 Other and unspecified drugs and medicaments
0.499 0.501 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.499 0.501 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.499 0.501 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.499 0.501 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.499 0.501 0.000
Y52 Agents primarily affecting the cardiovascular system
0.499 0.501 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.499 0.501 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.499 0.501 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.499 0.501 0.000
Y48 Anaesthetics and therapeutic gases
0.499 0.501 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.499 0.501 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.499 0.501 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.499 0.501 0.000
Y44 Agents primarily affecting blood constituents
0.499 0.501 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.499 0.501 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.499 0.501 0.000
Y40 Systemic antibiotics
0.499 0.501 0.000
D50.1 Sideropenic dysphagia
0.498 0.501 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.498 0.501 0.000
D12.5 Sigmoid colon
0.498 0.502 0.000
K62.8 Other specified diseases of anus and rectum
0.497 0.503 0.000
J90-J94 Other diseases of pleura
0.495 0.505 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.495 0.505 0.000
I25.1 Atherosclerotic heart disease
0.495 0.505 0.000
I63 Cerebral infarction
0.494 0.506 0.000
C78.2 Secondary malignant neoplasm of pleura
0.494 0.506 0.000
G20-G26 Extrapyramidal and movement disorders
0.494 0.506 0.000
K70-K77 Diseases of liver
0.492 0.507 0.000
L75 Apocrine sweat disorders
0.492 0.507 0.000
L74 Eccrine sweat disorders
0.492 0.507 0.000
L73 Other follicular disorders
0.492 0.507 0.000
L71 Rosacea
0.492 0.507 0.000
L70 Acne
0.492 0.507 0.000
L68 Hypertrichosis
0.492 0.507 0.000
L67 Hair colour and hair shaft abnormalities
0.492 0.507 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.492 0.507 0.000
L65 Other nonscarring hair loss
0.492 0.507 0.000
L64 Androgenic alopecia
0.492 0.507 0.000
L63 Alopecia areata
0.492 0.507 0.000
L62 Nail disorders in diseases classified elsewhere
0.492 0.507 0.000
N80 Endometriosis
0.492 0.508 0.000
I09 Other rheumatic heart diseases
0.491 0.509 0.000
I07 Rheumatic tricuspid valve diseases
0.491 0.509 0.000
I06 Rheumatic aortic valve diseases
0.491 0.509 0.000
I05 Rheumatic mitral valve diseases
0.491 0.509 0.000
C67 Malignant neoplasm of bladder
0.489 0.511 0.000
H66 Suppurative and unspecified otitis media
0.488 0.512 0.000
L72.0 Epidermal cyst
0.488 0.512 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.487 0.513 0.000
L40 Psoriasis
0.486 0.513 0.000
J00-J06 Acute upper respiratory infections
0.486 0.514 0.000
L03.1 Cellulitis of other parts of limb
0.486 0.514 0.000
I46.0 Cardiac arrest with successful resuscitation
0.485 0.514 0.000
K65-K67 Diseases of peritoneum
0.485 0.515 0.000
A04.8 Other specified bacterial intestinal infections
0.485 0.515 0.000
Chapter V Mental and behavioural disorders
0.484 0.516 0.000
N25-N29 Other disorders of kidney and ureter
0.483 0.517 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.483 0.517 0.000
E04.1 Non-toxic single thyroid nodule
0.482 0.518 0.000
K35 Acute appendicitis
0.482 0.518 0.000
D12.8 Rectum
0.482 0.518 0.000
N89 Other noninflammatory disorders of vagina
0.481 0.519 0.000
N30-N39 Other diseases of urinary system
0.481 0.519 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.481 0.519 0.000
C95 Leukaemia of unspecified cell type
0.481 0.519 0.000
C94 Other leukaemias of specified cell type
0.481 0.519 0.000
C93 Monocytic leukaemia
0.481 0.519 0.000
C92 Myeloid leukaemia
0.481 0.519 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.481 0.519 0.000
C88 Malignant immunoproliferative diseases
0.481 0.519 0.000
C86 Other specified types of T/NK-cell lymphoma
0.481 0.519 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.481 0.519 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.481 0.519 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.481 0.519 0.000
C81 Hodgkin's disease
0.481 0.519 0.000
C50-C50 Malignant neoplasm of breast
0.480 0.519 0.000
D05 Carcinoma in situ of breast
0.479 0.521 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.479 0.521 0.000
S62 Fracture at wrist and hand level
0.479 0.521 0.000
S52 Fracture of forearm
0.478 0.521 0.000
L08 Other local infections of skin and subcutaneous tissue
0.477 0.522 0.000
D24 Benign neoplasm of breast
0.475 0.525 0.000
C77.9 Lymph node, unspecified
0.475 0.525 0.000
C77.8 Lymph nodes of multiple regions
0.475 0.525 0.000
C77.5 Intrapelvic lymph nodes
0.475 0.525 0.000
C77.4 Inguinal and lower limb lymph nodes
0.475 0.525 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.475 0.525 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.475 0.525 0.000
D46 Myelodysplastic syndromes
0.475 0.525 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.475 0.525 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.475 0.525 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.475 0.525 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.475 0.525 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.475 0.525 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.475 0.525 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.475 0.525 0.000
D45 Polycythaemia vera
0.475 0.525 0.000
K60 Fissure and fistula of anal and rectal regions
0.474 0.526 0.000
H73 Other disorders of tympanic membrane
0.473 0.527 0.000
D68 Other coagulation defects
0.473 0.527 0.000
D67 Hereditary factor IX deficiency
0.473 0.527 0.000
D66 Hereditary factor VIII deficiency
0.473 0.527 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.473 0.527 0.000
K41 Femoral hernia
0.473 0.527 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.473 0.527 0.000
L03.8 Cellulitis of other sites
0.471 0.529 0.000
L03.0 Cellulitis of finger and toe
0.471 0.529 0.000
P90-P96 Other disorders originating in the perinatal period
0.471 0.529 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.471 0.529 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.471 0.529 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.471 0.529 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.471 0.529 0.000
P35-P39 Infections specific to the perinatal period
0.471 0.529 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.471 0.529 0.000
P10-P15 Birth trauma
0.471 0.529 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.471 0.529 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.471 0.529 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.471 0.529 0.000
Q80-Q89 Other congenital malformations
0.471 0.529 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.471 0.529 0.000
Q60-Q64 Congenital malformations of the urinary system
0.471 0.529 0.000
Q50-Q56 Congenital malformations of genital organs
0.471 0.529 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.471 0.529 0.000
Q35-Q37 Cleft lip and cleft palate
0.471 0.529 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.471 0.529 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.471 0.529 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.471 0.529 0.000
Q00-Q07 Congenital malformations of the nervous system
0.471 0.529 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.471 0.529 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.471 0.529 0.000
I31.9 Disease of pericardium, unspecified
0.470 0.529 0.000
I31.8 Other specified diseases of pericardium
0.470 0.529 0.000
I31.2 Haemopericardium, not elsewhere classified
0.470 0.529 0.000
I31.1 Chronic constrictive pericarditis
0.470 0.529 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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