TreeWAS – Variant ID: rs191448950

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.001	0.999
Chapter X Diseases of the respiratory system	0.995	0.005	0.000
I20-I25 Ischaemic heart diseases	0.000	0.006	0.994
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.007	0.993
M20-M25 Other joint disorders	0.989	0.011	0.000
M70-M79 Other soft tissue disorders	0.988	0.012	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.013	0.987
I25.2 Old myocardial infarction	0.000	0.014	0.986
I21 Acute myocardial infarction	0.000	0.017	0.983
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.977	0.023	0.000
M75 Shoulder lesions	0.976	0.024	0.000
J30-J39 Other diseases of upper respiratory tract	0.975	0.025	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.026	0.974
Chapter II Neoplasms	0.970	0.030	0.000
M23 Internal derangement of knee	0.966	0.034	0.000
D10-D36 Benign neoplasms	0.960	0.040	0.000
J40-J47 Chronic lower respiratory diseases	0.951	0.049	0.000
I20 Angina pectoris	0.000	0.051	0.949
Chapter XIV Diseases of the genitourinary system	0.945	0.055	0.000
M75.1 Rotator cuff syndrome	0.943	0.057	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.059	0.941
M23.2 Derangement of meniscus due to old tear or injury	0.938	0.062	0.000
Chapter VIII Diseases of the ear and mastoid process	0.934	0.066	0.000
J34 Other disorders of nose and nasal sinuses	0.933	0.067	0.000
D23 Other benign neoplasms of skin	0.928	0.072	0.000
Chapter XX External causes of morbidity and mortality	0.910	0.090	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.909	0.091	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.106	0.894
Chapter VII Diseases of the eye and adnexa	0.892	0.108	0.000
M15-M19 Arthrosis	0.891	0.109	0.000
H65-H75 Diseases of middle ear and mastoid	0.891	0.109	0.000
S00-S09 Injuries to the head	0.890	0.110	0.000
D22 Melanocytic naevi	0.889	0.111	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.883	0.117	0.000
I20.9 Angina pectoris, unspecified	0.000	0.125	0.875
M75.4 Impingement syndrome of shoulder	0.871	0.129	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.868	0.132	0.000
M20 Acquired deformities of fingers and toes	0.866	0.134	0.000
J34.2 Deviated nasal septum	0.863	0.137	0.000
M17 Gonarthrosis [arthrosis of knee]	0.853	0.147	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.853	0.147	0.000
M05-M14 Inflammatory polyarthropathies	0.852	0.148	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.149	0.851
J34.3 Hypertrophy of nasal turbinates	0.839	0.161	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.836	0.164	0.000
M17.9 Gonarthrosis, unspecified	0.835	0.165	0.000
M65-M68 Disorders of synovium and tendon	0.832	0.168	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.832	0.168	0.000
I20.0 Unstable angina	0.000	0.169	0.831
N30-N39 Other diseases of urinary system	0.830	0.170	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.830	0.170	0.000
M35 Other systemic involvement of connective tissue	0.829	0.171	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.829	0.171	0.000
S80-S89 Injuries to the knee and lower leg	0.829	0.171	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.826	0.174	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.826	0.174	0.000
J43 Emphysema	0.821	0.179	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.821	0.179	0.000
Chapter V Mental and behavioural disorders	0.818	0.182	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.816	0.184	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.815	0.185	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.814	0.185	0.000
H65 Nonsuppurative otitis media	0.812	0.188	0.000
E70-E90 Metabolic disorders	0.019	0.190	0.791
N81 Female genital prolapse	0.809	0.191	0.000
M71 Other bursopathies	0.802	0.198	0.000
M20.1 Hallux valgus (acquired)	0.801	0.199	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.799	0.201	0.000
D23.1 Skin of eyelid, including canthus	0.798	0.202	0.000
J32 Chronic sinusitis	0.795	0.205	0.000
J45 Asthma	0.793	0.207	0.000
M75.0 Adhesive capsulitis of shoulder	0.791	0.209	0.000
N81.2 Incomplete uterovaginal prolapse	0.783	0.217	0.000
D23.4 Skin of scalp and neck	0.777	0.223	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.777	0.223	0.000
M23.3 Other meniscus derangements	0.776	0.224	0.000
S60-S69 Injuries to the wrist and hand	0.775	0.225	0.000
J33 Nasal polyp	0.773	0.227	0.000
N20-N23 Urolithiasis	0.769	0.231	0.000
J40 Bronchitis, not specified as acute or chronic	0.769	0.231	0.000
D23.3 Skin of other and unspecified parts of face	0.762	0.238	0.000
J47 Bronchiectasis	0.761	0.238	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.760	0.240	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.759	0.241	0.000
S50-S59 Injuries to the elbow and forearm	0.758	0.242	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.756	0.244	0.000
H72 Perforation of tympanic membrane	0.753	0.247	0.000
D32 Benign neoplasm of meninges	0.751	0.249	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.751	0.249	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.750	0.249	0.000
N88 Other noninflammatory disorders of cervix uteri	0.750	0.250	0.000
D23.7 Skin of lower limb, including hip	0.749	0.251	0.000
N39 Other disorders of urinary system	0.749	0.251	0.000
D17 Benign lipomatous neoplasm	0.747	0.253	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.747	0.253	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.745	0.255	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.744	0.256	0.000
X20-X29 Contact with venomous animals and plants	0.741	0.259	0.000
D22.4 Melanocytic naevi of scalp and neck	0.741	0.259	0.000
D12.0 Caecum	0.740	0.260	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.739	0.261	0.000
F30-F39 Mood [affective] disorders	0.734	0.266	0.000
N95 Menopausal and other perimenopausal disorders	0.732	0.268	0.000
S00 Superficial injury of head	0.732	0.268	0.000
C64-C68 Malignant neoplasms of urinary tract	0.731	0.269	0.000
M13 Other arthritis	0.730	0.270	0.000
J20-J22 Other acute lower respiratory infections	0.729	0.271	0.000
M23.8 Other internal derangements of knee	0.728	0.271	0.000
J43.9 Emphysema, unspecified	0.728	0.272	0.000
J39 Other diseases of upper respiratory tract	0.728	0.272	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.728	0.272	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.727	0.273	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.727	0.273	0.000
J00-J06 Acute upper respiratory infections	0.726	0.274	0.000
H40-H42 Glaucoma	0.725	0.275	0.000
M72 Fibroblastic disorders	0.724	0.275	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.724	0.276	0.000
N84 Polyp of female genital tract	0.723	0.277	0.000
C51-C58 Malignant neoplasms of female genital organs	0.723	0.277	0.000
M40-M43 Deforming dorsopathies	0.722	0.278	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.721	0.279	0.000
J35 Chronic diseases of tonsils and adenoids	0.720	0.280	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.718	0.282	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.717	0.283	0.000
Chapter XXII Codes for special purposes	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.5 Ischaemic cardiomyopathy	0.000	0.283	0.717
I25.4 Coronary artery aneurysm	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.717	0.283	0.000
M91-M94 Chondropathies	0.717	0.283	0.000
M86-M90 Other osteopathies	0.717	0.283	0.000
M60-M63 Disorders of muscles	0.717	0.283	0.000
M00-M03 Infectious arthropathies	0.717	0.283	0.000
J44 Other chronic obstructive pulmonary disease	0.717	0.283	0.000
T81 Complications of procedures, not elsewhere classified	0.716	0.284	0.000
N30 Cystitis	0.715	0.285	0.000
M35.3 Polymyalgia rheumatica	0.715	0.285	0.000
S01 Open wound of head	0.714	0.286	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.713	0.287	0.000
I24 Other acute ischaemic heart diseases	0.000	0.287	0.712
I23 Certain current complications following acute myocardial infarction	0.000	0.287	0.712
N87 Dysplasia of cervix uteri	0.712	0.288	0.000
J84 Other interstitial pulmonary diseases	0.712	0.288	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.711	0.289	0.000
H65.3 Chronic mucoid otitis media	0.711	0.289	0.000
S82 Fracture of lower leg, including ankle	0.711	0.289	0.000
N94.6 Dysmenorrhoea, unspecified	0.711	0.289	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.291	0.000
M34 Systemic sclerosis	0.709	0.291	0.000
M33 Dermatopolymyositis	0.709	0.291	0.000
M32 Systemic lupus erythematosus	0.709	0.291	0.000
M31 Other necrotising vasculopathies	0.709	0.291	0.000
M30 Polyarteritis nodosa and related conditions	0.709	0.291	0.000
M24 Other specific joint derangements	0.709	0.291	0.000
M22 Disorders of patella	0.709	0.291	0.000
M21 Other acquired deformities of limbs	0.709	0.291	0.000
D23.6 Skin of upper limb, including shoulder	0.709	0.291	0.000
M77 Other enthesopathies	0.709	0.291	0.000
M76 Enthesopathies of lower limb, excluding foot	0.709	0.291	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.709	0.291	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.709	0.291	0.000
S09 Other and unspecified injuries of head	0.708	0.292	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.292	0.708
E78.8 Other disorders of lipoprotein metabolism	0.000	0.292	0.708
E78.6 Lipoprotein deficiency	0.000	0.292	0.708
E78.4 Other hyperlipidaemia	0.000	0.292	0.708
E78.3 Hyperchylomicronaemia	0.000	0.292	0.708
E78.2 Mixed hyperlipidaemia	0.000	0.292	0.708
E78.1 Pure hyperglyceridaemia	0.000	0.292	0.708
N90 Other noninflammatory disorders of vulva and perineum	0.706	0.294	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.295	0.705
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.295	0.705
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.295	0.705
D24 Benign neoplasm of breast	0.705	0.295	0.000
N99-N99 Other disorders of the genitourinary system	0.704	0.296	0.000
N25-N29 Other disorders of kidney and ureter	0.703	0.297	0.000
D23.5 Skin of trunk	0.701	0.299	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.700	0.299	0.000
T79-T79 Certain early complications of trauma	0.700	0.299	0.000
T66-T78 Other and unspecified effects of external causes	0.700	0.299	0.000
T33-T35 Frostbite	0.700	0.299	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.700	0.299	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.700	0.299	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.700	0.299	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.700	0.299	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.700	0.299	0.000
T00-T07 Injuries involving multiple body regions	0.700	0.299	0.000
S90-S99 Injuries to the ankle and foot	0.700	0.299	0.000
S10-S19 Injuries to the neck	0.700	0.299	0.000
N00-N08 Glomerular diseases	0.700	0.300	0.000
M75.8 Other shoulder lesions	0.700	0.300	0.000
M75.9 Shoulder lesion, unspecified	0.700	0.300	0.000
M75.3 Calcific tendinitis of shoulder	0.700	0.300	0.000
M75.2 Bicipital tendinitis	0.700	0.300	0.000
D11 Benign neoplasm of major salivary glands	0.700	0.300	0.000
J60-J70 Lung diseases due to external agents	0.700	0.300	0.000
J37 Chronic laryngitis and laryngotracheitis	0.699	0.301	0.000
J36 Peritonsillar abscess	0.699	0.301	0.000
M75.5 Bursitis of shoulder	0.698	0.302	0.000
M80-M85 Disorders of bone density and structure	0.698	0.302	0.000
H10-H13 Disorders of conjunctiva	0.698	0.302	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.697	0.303	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.697	0.303	0.000
S70-S79 Injuries to the hip and thigh	0.696	0.304	0.000
S02 Fracture of skull and facial bones	0.696	0.304	0.000
N39.3 Stress incontinence	0.696	0.304	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.304	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.695	0.304	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.695	0.304	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.695	0.304	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.304	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.695	0.304	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.695	0.305	0.000
M18 Arthrosis of first carpometacarpal joint	0.695	0.305	0.000
I22 Subsequent myocardial infarction	0.000	0.307	0.693
R21 Rash and other nonspecific skin eruption	0.693	0.307	0.000
M23.9 Internal derangement of knee, unspecified	0.692	0.307	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.692	0.307	0.000
M23.5 Chronic instability of knee	0.692	0.307	0.000
M23.4 Loose body in knee	0.692	0.307	0.000
M23.1 Discoid meniscus (congenital)	0.692	0.307	0.000
M23.0 Cystic meniscus	0.692	0.307	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.692	0.308	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.691	0.309	0.000
M67 Other disorders of synovium and tendon	0.691	0.309	0.000
S40-S49 Injuries to the shoulder and upper arm	0.690	0.309	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.690	0.310	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.689	0.311	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.689	0.311	0.000
D36 Benign neoplasm of other and unspecified sites	0.688	0.312	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.688	0.312	0.000
D31 Benign neoplasm of eye and adnexa	0.688	0.312	0.000
D30 Benign neoplasm of urinary organs	0.688	0.312	0.000
D29 Benign neoplasm of male genital organs	0.688	0.312	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.688	0.312	0.000
D26 Other benign neoplasms of uterus	0.688	0.312	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.688	0.312	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.688	0.312	0.000
D19 Benign neoplasm of mesothelial tissue	0.688	0.312	0.000
D16 Benign neoplasm of bone and articular cartilage	0.688	0.312	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.688	0.312	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.688	0.312	0.000
D10 Benign neoplasm of mouth and pharynx	0.688	0.312	0.000
D34 Benign neoplasm of thyroid gland	0.688	0.312	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.686	0.314	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.685	0.315	0.000
I20.8 Other forms of angina pectoris	0.000	0.316	0.684
H71 Cholesteatoma of middle ear	0.684	0.316	0.000
C91 Lymphoid leukaemia	0.683	0.317	0.000
F32 Depressive episode	0.683	0.317	0.000
H53-H54 Visual disturbances and blindness	0.683	0.317	0.000
M20.5 Other deformities of toe(s) (acquired)	0.682	0.318	0.000
J09-J18 Influenza and pneumonia	0.682	0.318	0.000
J41 Simple and mucopurulent chronic bronchitis	0.682	0.318	0.000
J46 Status asthmaticus	0.682	0.318	0.000
J42 Unspecified chronic bronchitis	0.682	0.318	0.000
H80-H83 Diseases of inner ear	0.682	0.318	0.000
N97 Female infertility	0.681	0.319	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.681	0.319	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.319	0.680
J45.9 Asthma, unspecified	0.680	0.320	0.000
J30 Vasomotor and allergic rhinitis	0.678	0.322	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.677	0.323	0.000
D18 Haemangioma and lymphangioma, any site	0.676	0.324	0.000
S20-S29 Injuries to the thorax	0.675	0.325	0.000
N17-N19 Renal failure	0.674	0.326	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.672	0.328	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.672	0.328	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.672	0.328	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.672	0.328	0.000
N60-N64 Disorders of breast	0.671	0.329	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.671	0.329	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.670	0.330	0.000
H60-H62 Diseases of external ear	0.670	0.330	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.011	0.331	0.658
J34.1 Cyst and mucocele of nose and nasal sinus	0.669	0.331	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.669	0.331	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.669	0.331	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.668	0.332	0.000
M07 Psoriatic and enteropathic arthropathies	0.667	0.333	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.667	0.333	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.666	0.334	0.000
D23.9 Skin, unspecified	0.665	0.335	0.000
D23.2 Skin of ear and external auricular canal	0.665	0.335	0.000
D23.0 Skin of lip	0.665	0.335	0.000
N39.4 Other specified urinary incontinence	0.665	0.335	0.000
H66 Suppurative and unspecified otitis media	0.665	0.335	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.664	0.336	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.662	0.338	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.007	0.338	0.655
H52 Disorders of refraction and accommodation	0.658	0.342	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.657	0.343	0.000
M50-M54 Other dorsopathies	0.657	0.343	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.655	0.345	0.000
J32.8 Other chronic sinusitis	0.655	0.345	0.000
D12.2 Ascending colon	0.654	0.346	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.654	0.346	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.652	0.348	0.000
Y35-Y36 Legal intervention and operations of war	0.652	0.348	0.000
Y10-Y34 Event of undetermined intent	0.652	0.348	0.000
Y00-Y09 Assault	0.652	0.348	0.000
X85-X99 Assault	0.652	0.348	0.000
X60-X84 Intentional self-harm	0.652	0.348	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.652	0.348	0.000
X50-X57 Overexertion, travel and privation	0.652	0.348	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.652	0.348	0.000
X30-X39 Exposure to forces of nature	0.652	0.348	0.000
X10-X19 Contact with heat and hot substances	0.652	0.348	0.000
X00-X09 Exposure to smoke, fire and flames	0.652	0.348	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.652	0.348	0.000
W75-W84 Other accidental threats to breathing	0.652	0.348	0.000
W65-W74 Accidental drowning and submersion	0.652	0.348	0.000
W50-W64 Exposure to animate mechanical forces	0.652	0.348	0.000
W20-W49 Exposure to inanimate mechanical forces	0.652	0.348	0.000
V98-V99 Other and unspecified transport accidents	0.652	0.348	0.000
V95-V97 Air and space transport accidents	0.652	0.348	0.000
V90-V94 Water transport accidents	0.652	0.348	0.000
V80-V89 Other land transport accidents	0.652	0.348	0.000
V70-V79 Bus occupant injured in transport accident	0.652	0.348	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.652	0.348	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.652	0.348	0.000
V40-V49 Car occupant injured in transport accident	0.652	0.348	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.652	0.348	0.000
V20-V29 Motorcycle rider injured in transport accident	0.652	0.348	0.000
V10-V19 Pedal cyclist injured in transport accident	0.652	0.348	0.000
V01-V09 Pedestrian injured in transport accident	0.652	0.348	0.000
N98 Complications associated with artificial fertilisation	0.652	0.348	0.000
N91 Absent, scanty and rare menstruation	0.652	0.348	0.000
N82 Fistulae involving female genital tract	0.652	0.348	0.000
N96 Habitual aborter	0.652	0.348	0.000
D45 Polycythaemia vera	0.651	0.349	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.350	0.650
N88.8 Other specified noninflammatory disorders of cervix uteri	0.648	0.352	0.000
F32.9 Depressive episode, unspecified	0.647	0.353	0.000
R17 Unspecified jaundice	0.645	0.355	0.000
R87 Abnormal findings in specimens from female genital organs	0.644	0.356	0.000
M13.9 Arthritis, unspecified	0.643	0.357	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.642	0.358	0.000
M11 Other crystal arthropathies	0.642	0.358	0.000
N83.2 Other and unspecified ovarian cysts	0.642	0.358	0.000
M25 Other joint disorders, not elsewhere classified	0.640	0.360	0.000
H55-H59 Other disorders of eye and adnexa	0.640	0.360	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.640	0.360	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.640	0.360	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.639	0.361	0.000
M15 Polyarthrosis	0.639	0.361	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.638	0.361	0.000
H74 Other disorders of middle ear and mastoid	0.638	0.361	0.000
H73 Other disorders of tympanic membrane	0.638	0.361	0.000
H70 Mastoiditis and related conditions	0.638	0.361	0.000
H69 Other disorders of Eustachian tube	0.638	0.361	0.000
H68 Eustachian salpingitis and obstruction	0.638	0.361	0.000
H67 Otitis media in diseases classified elsewhere	0.638	0.361	0.000
S08 Traumatic amputation of part of head	0.638	0.361	0.000
S07 Crushing injury of head	0.638	0.361	0.000
S06 Intracranial injury	0.638	0.361	0.000
S05 Injury of eye and orbit	0.638	0.361	0.000
S04 Injury of cranial nerves	0.638	0.361	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.638	0.361	0.000
D12.6 Colon, unspecified	0.638	0.362	0.000
D22.9 Melanocytic naevi, unspecified	0.637	0.362	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.637	0.362	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.637	0.362	0.000
D22.0 Melanocytic naevi of lip	0.637	0.362	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.637	0.363	0.000
H25-H28 Disorders of lens	0.636	0.364	0.000
C60-C63 Malignant neoplasms of male genital organs	0.636	0.364	0.000
H90-H95 Other disorders of ear	0.635	0.365	0.000
R30-R39 Symptoms and signs involving the urinary system	0.635	0.365	0.000
M10 Gout	0.635	0.365	0.000
Q21 Congenital malformations of cardiac septa	0.634	0.366	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.633	0.367	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.633	0.367	0.000
J33.0 Polyp of nasal cavity	0.632	0.368	0.000
M65 Synovitis and tenosynovitis	0.631	0.369	0.000
N86 Erosion and ectropion of cervix uteri	0.630	0.370	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.630	0.370	0.000
D80-D89 Certain disorders involving the immune mechanism	0.629	0.371	0.000
Y83.8 Other surgical procedures	0.629	0.371	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.373	0.627
N95.2 Postmenopausal atrophic vaginitis	0.626	0.374	0.000
Chapter I Certain infectious and parasitic diseases	0.623	0.377	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.622	0.377	0.000
T87 Complications peculiar to reattachment and amputation	0.622	0.377	0.000
T86 Failure and rejection of transplanted organs and tissues	0.622	0.377	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.622	0.377	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.622	0.377	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.622	0.377	0.000
N20 Calculus of kidney and ureter	0.622	0.378	0.000
D12.7 Rectosigmoid junction	0.622	0.378	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.621	0.379	0.000
M20.3 Other deformity of hallux (acquired)	0.621	0.379	0.000
M20.0 Deformity of finger(s)	0.621	0.379	0.000
X23 Contact with hornets, wasps and bees	0.621	0.379	0.000
R94 Abnormal results of function studies	0.619	0.380	0.000
N92 Excessive, frequent and irregular menstruation	0.619	0.381	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.619	0.381	0.000
S00.8 Superficial injury of other parts of head	0.618	0.382	0.000
R47-R49 Symptoms and signs involving speech and voice	0.616	0.384	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.615	0.384	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.615	0.385	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.615	0.385	0.000
N81.3 Complete uterovaginal prolapse	0.615	0.385	0.000
D00-D09 In situ neoplasms	0.614	0.386	0.000
M17.1 Other primary gonarthrosis	0.612	0.388	0.000
M17.5 Other secondary gonarthrosis	0.612	0.388	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.612	0.388	0.000
M17.3 Other posttraumatic gonarthrosis	0.612	0.388	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.612	0.388	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.611	0.388	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.611	0.389	0.000
C95 Leukaemia of unspecified cell type	0.611	0.389	0.000
C94 Other leukaemias of specified cell type	0.611	0.389	0.000
C93 Monocytic leukaemia	0.611	0.389	0.000
C92 Myeloid leukaemia	0.611	0.389	0.000
C88 Malignant immunoproliferative diseases	0.611	0.389	0.000
C86 Other specified types of T/NK-cell lymphoma	0.611	0.389	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.611	0.389	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.611	0.389	0.000
C81 Hodgkin's disease	0.611	0.389	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.611	0.389	0.000
M14 Arthropathies in other diseases classified elsewhere	0.611	0.389	0.000
M12 Other specific arthropathies	0.611	0.389	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.611	0.389	0.000
M08 Juvenile arthritis	0.611	0.389	0.000
M05 Seropositive rheumatoid arthritis	0.611	0.389	0.000
N84.1 Polyp of cervix uteri	0.611	0.389	0.000
Chapter XI Diseases of the digestive system	0.606	0.394	0.000
D50-D53 Nutritional anaemias	0.605	0.395	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.605	0.395	0.000
H40 Glaucoma	0.605	0.395	0.000
H43-H45 Disorders of vitreous body and globe	0.604	0.396	0.000
D27 Benign neoplasm of ovary	0.604	0.396	0.000
J90-J94 Other diseases of pleura	0.603	0.397	0.000
L03 Cellulitis	0.603	0.397	0.000
J32.9 Chronic sinusitis, unspecified	0.603	0.397	0.000
D32.0 Cerebral meninges	0.602	0.398	0.000
S52 Fracture of forearm	0.601	0.399	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.600	0.400	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.599	0.401	0.000
Q80-Q89 Other congenital malformations	0.599	0.401	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.599	0.401	0.000
Q60-Q64 Congenital malformations of the urinary system	0.599	0.401	0.000
Q50-Q56 Congenital malformations of genital organs	0.599	0.401	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.599	0.401	0.000
Q35-Q37 Cleft lip and cleft palate	0.599	0.401	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.599	0.401	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.599	0.401	0.000
Q00-Q07 Congenital malformations of the nervous system	0.599	0.401	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.599	0.401	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.396	0.401	0.203
C67 Malignant neoplasm of bladder	0.598	0.402	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.598	0.402	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.597	0.403	0.000
M72.2 Plantar fascial fibromatosis	0.597	0.403	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.596	0.403	0.000
M66 Spontaneous rupture of synovium and tendon	0.596	0.403	0.000
S61 Open wound of wrist and hand	0.595	0.405	0.000
N37 Urethral disorders in diseases classified elsewhere	0.595	0.405	0.000
N36 Other disorders of urethra	0.595	0.405	0.000
N34 Urethritis and urethral syndrome	0.595	0.405	0.000
N33 Bladder disorders in diseases classified elsewhere	0.595	0.405	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.595	0.405	0.000
M35.8 Other specified systemic involvement of connective tissue	0.595	0.405	0.000
M35.7 Hypermobility syndrome	0.595	0.405	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.595	0.405	0.000
M35.5 Multifocal fibrosclerosis	0.595	0.405	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.595	0.405	0.000
M35.2 Behcet's disease	0.595	0.405	0.000
M35.1 Other overlap syndromes	0.595	0.405	0.000
M35.0 Sicca syndrome [Sjogren]	0.595	0.405	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.595	0.405	0.000
J80 Adult respiratory distress syndrome	0.595	0.405	0.000
N93 Other abnormal uterine and vaginal bleeding	0.595	0.405	0.000
S01.8 Open wound of other parts of head	0.595	0.405	0.000
S89 Other and unspecified injuries of lower leg	0.594	0.405	0.000
S88 Traumatic amputation of lower leg	0.594	0.405	0.000
S87 Crushing injury of lower leg	0.594	0.405	0.000
S86 Injury of muscle and tendon at lower leg level	0.594	0.405	0.000
S85 Injury of blood vessels at lower leg level	0.594	0.405	0.000
S84 Injury of nerves at lower leg level	0.594	0.405	0.000
S81 Open wound of lower leg	0.594	0.405	0.000
S80 Superficial injury of lower leg	0.594	0.405	0.000
H30-H36 Disorders of choroid and retina	0.594	0.406	0.000
Chapter VI Diseases of the nervous system	0.594	0.406	0.000
R22.1 Localised swelling, mass and lump, neck	0.593	0.407	0.000
J81 Pulmonary oedema	0.593	0.407	0.000
L50-L54 Urticaria and erythema	0.592	0.408	0.000
L10-L14 Bullous disorders	0.592	0.408	0.000
M45-M49 Spondylopathies	0.592	0.408	0.000
M67.8 Other specified disorders of synovium and tendon	0.590	0.410	0.000
J31.0 Chronic rhinitis	0.590	0.410	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.590	0.410	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations