TreeWAS – Variant ID: rs192772225

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.011	0.989
K52 Other non-infective gastro-enteritis and colitis	0.009	0.991
K50-K52 Noninfective enteritis and colitis	0.007	0.993
K52.8 Other specified non-infective gastro-enteritis and colitis	0.006	0.993
K52.3 Indeterminate colitis	0.006	0.993
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.006	0.993
K52.1 Toxic gastro-enteritis and colitis	0.006	0.993
K52.0 Gastro-enteritis and colitis due to radiation	0.006	0.993
# Top node	0.006	0.994
Chapter XI Diseases of the digestive system	0.006	0.994
Chapter IX Diseases of the circulatory system	0.006	0.994
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.005	0.995
K51 Ulcerative colitis	0.005	0.995
K50 Crohn's disease [regional enteritis]	0.005	0.995
Chapter VII Diseases of the eye and adnexa	0.005	0.995
Chapter XXI Factors influencing health status and contact with health services	0.005	0.995
I20-I25 Ischaemic heart diseases	0.005	0.995
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.005	0.995
Chapter I Certain infectious and parasitic diseases	0.005	0.995
H25-H28 Disorders of lens	0.005	0.995
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.005	0.995
Chapter XII Diseases of the skin and subcutaneous tissue	0.005	0.995
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.005	0.995
Chapter II Neoplasms	0.005	0.995
Chapter XXII Codes for special purposes	0.005	0.995
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995
Chapter XVI Certain conditions originating in the perinatal period	0.005	0.995
Chapter XV Pregnancy, childbirth and the puerperium	0.005	0.995
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.005	0.995
Chapter VIII Diseases of the ear and mastoid process	0.005	0.995
Z40-Z54 Persons encountering health services for specific procedures and health care	0.005	0.995
Chapter XX External causes of morbidity and mortality	0.005	0.995
Chapter VI Diseases of the nervous system	0.004	0.995
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.004	0.995
Chapter X Diseases of the respiratory system	0.004	0.995
K90-K93 Other diseases of the digestive system	0.004	0.995
K70-K77 Diseases of liver	0.004	0.995
K65-K67 Diseases of peritoneum	0.004	0.995
K35-K38 Diseases of appendix	0.004	0.995
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.004	0.995
Chapter V Mental and behavioural disorders	0.004	0.995
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.004	0.995
H26 Other cataract	0.004	0.995
Z51 Other medical care	0.004	0.995
Z00-Z13 Persons encountering health services for examination and investigation	0.004	0.995
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996
R10 Abdominal and pelvic pain	0.004	0.996
I10-I15 Hypertensive diseases	0.004	0.996
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.004	0.996
H26.9 Cataract, unspecified	0.004	0.996
I95-I99 Other and unspecified disorders of the circulatory system	0.004	0.996
I70-I79 Diseases of arteries, arterioles and capillaries	0.004	0.996
I60-I69 Cerebrovascular diseases	0.004	0.996
I30-I52 Other forms of heart disease	0.004	0.996
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.004	0.996
I05-I09 Chronic rheumatic heart diseases	0.004	0.996
I00-I02 Acute rheumatic fever	0.004	0.996
I20 Angina pectoris	0.004	0.996
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.004	0.996
Chapter IV Endocrine, nutritional and metabolic diseases	0.004	0.996
K55-K64 Other diseases of intestines	0.004	0.996
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.004	0.996
R10.3 Pain localised to other parts of lower abdomen	0.004	0.996
K40-K46 Hernia	0.004	0.996
R95-R99 Ill-defined and unknown causes of mortality	0.004	0.996
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.004	0.996
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.004	0.996
R47-R49 Symptoms and signs involving speech and voice	0.004	0.996
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.004	0.996
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.004	0.996
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.004	0.996
K50.9 Crohn's disease, unspecified	0.004	0.996
K50.8 Other Crohn's disease	0.004	0.996
K50.1 Crohn's disease of large intestine	0.004	0.996
K50.0 Crohn's disease of small intestine	0.004	0.996
K51.9 Ulcerative colitis, unspecified	0.004	0.996
K51.8 Other ulcerative colitis	0.004	0.996
K51.5 Mucosal proctocolitis	0.004	0.996
K51.4 Pseudopolyposis of colon	0.004	0.996
K51.3 Ulcerative (chronic) rectosigmoiditis	0.004	0.996
K51.2 Ulcerative (chronic) proctitis	0.004	0.996
K51.1 Ulcerative (chronic) ileocolitis	0.004	0.996
K51.0 Ulcerative (chronic) enterocolitis	0.004	0.996
Z51.1 Chemotherapy session for neoplasm	0.004	0.996
I25 Chronic ischaemic heart disease	0.004	0.996
H55-H59 Other disorders of eye and adnexa	0.004	0.996
H53-H54 Visual disturbances and blindness	0.004	0.996
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.004	0.996
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996
H43-H45 Disorders of vitreous body and globe	0.004	0.996
H40-H42 Glaucoma	0.004	0.996
H30-H36 Disorders of choroid and retina	0.004	0.996
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996
H10-H13 Disorders of conjunctiva	0.004	0.996
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.004	0.996
Chapter XIV Diseases of the genitourinary system	0.004	0.996
M70-M79 Other soft tissue disorders	0.004	0.996
I84 Haemorrhoids	0.004	0.996
I21 Acute myocardial infarction	0.004	0.996
M20-M25 Other joint disorders	0.004	0.996
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.004	0.996
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.004	0.996
R91 Abnormal findings on diagnostic imaging of lung	0.004	0.996
B95-B98 Bacterial, viral and other infectious agents	0.004	0.996
R19 Other symptoms and signs involving the digestive system and abdomen	0.004	0.996
Z51.2 Other chemotherapy	0.004	0.996
F40-F48 Neurotic, stress-related and somatoform disorders	0.004	0.996
I24 Other acute ischaemic heart diseases	0.004	0.996
I23 Certain current complications following acute myocardial infarction	0.004	0.996
I22 Subsequent myocardial infarction	0.004	0.996
R30-R39 Symptoms and signs involving the urinary system	0.004	0.996
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.004	0.996
M91-M94 Chondropathies	0.004	0.996
M86-M90 Other osteopathies	0.004	0.996
M80-M85 Disorders of bone density and structure	0.004	0.996
M65-M68 Disorders of synovium and tendon	0.004	0.996
M60-M63 Disorders of muscles	0.004	0.996
M50-M54 Other dorsopathies	0.004	0.996
M45-M49 Spondylopathies	0.004	0.996
M40-M43 Deforming dorsopathies	0.004	0.996
M05-M14 Inflammatory polyarthropathies	0.004	0.996
M00-M03 Infectious arthropathies	0.004	0.996
A00-A09 Intestinal infectious diseases	0.004	0.996
L80-L99 Other disorders of the skin and subcutaneous tissue	0.004	0.996
B99-B99 Other infectious diseases	0.004	0.996
B90-B94 Sequelae of infectious and parasitic diseases	0.004	0.996
B85-B89 Pediculosis, acariasis and other infestations	0.004	0.996
B65-B83 Helminthiases	0.004	0.996
B50-B64 Protozoal diseases	0.004	0.996
B35-B49 Mycoses	0.004	0.996
B25-B34 Other viral diseases	0.004	0.996
B20-B24 Human immunodeficiency virus [HIV] disease	0.004	0.996
B15-B19 Viral hepatitis	0.004	0.996
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.004	0.996
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.004	0.996
A80-A89 Viral infections of the central nervous system	0.004	0.996
A75-A79 Rickettsioses	0.004	0.996
A70-A74 Other diseases caused by chlamydiae	0.004	0.996
A65-A69 Other spirochaetal diseases	0.004	0.996
A50-A64 Infections with a predominantly sexual mode of transmission	0.004	0.996
A30-A49 Other bacterial diseases	0.004	0.996
A20-A28 Certain zoonotic bacterial diseases	0.004	0.996
A15-A19 Tuberculosis	0.004	0.996
R10.4 Other and unspecified abdominal pain	0.004	0.996
Z13 Special screening examination for other diseases and disorders	0.004	0.996
I20.0 Unstable angina	0.004	0.996
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.003	0.996
H27 Other disorders of lens	0.003	0.996
H25 Senile cataract	0.003	0.996
C50-C50 Malignant neoplasm of breast	0.004	0.996
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.004	0.996
R18 Ascites	0.004	0.996
R17 Unspecified jaundice	0.004	0.996
R15 Faecal incontinence	0.004	0.996
R14 Flatulence and related conditions	0.004	0.996
R12 Heartburn	0.004	0.996
L60-L75 Disorders of skin appendages	0.003	0.996
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.003	0.996
L50-L54 Urticaria and erythema	0.003	0.996
L40-L45 Papulosquamous disorders	0.003	0.996
L20-L30 Dermatitis and eczema	0.003	0.996
L10-L14 Bullous disorders	0.003	0.996
L00-L08 Infections of the skin and subcutaneous tissue	0.003	0.996
Z08 Follow-up examination after treatment for malignant neoplasm	0.004	0.996
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.996
I88 Nonspecific lymphadenitis	0.003	0.996
I87 Other disorders of veins	0.003	0.996
I86 Varicose veins of other sites	0.003	0.996
I85 Oesophageal varices	0.003	0.996
I83 Varicose veins of lower extremities	0.004	0.996
I82 Other venous embolism and thrombosis	0.003	0.996
I80 Phlebitis and thrombophlebitis	0.003	0.996
I81 Portal vein thrombosis	0.003	0.996
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.996
D10-D36 Benign neoplasms	0.003	0.996
D00-D09 In situ neoplasms	0.003	0.996
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.003	0.996
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.003	0.996
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.003	0.996
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.003	0.996
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.003	0.996
C64-C68 Malignant neoplasms of urinary tract	0.003	0.996
C60-C63 Malignant neoplasms of male genital organs	0.003	0.996
C51-C58 Malignant neoplasms of female genital organs	0.003	0.996
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.003	0.996
C43-C44 Melanoma and other malignant neoplasms of skin	0.003	0.996
C40-C41 Malignant neoplasms of bone and articular cartilage	0.003	0.996
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.003	0.996
C15-C26 Malignant neoplasms of digestive organs	0.003	0.996
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.003	0.996
R07 Pain in throat and chest	0.004	0.996
R13 Dysphagia	0.004	0.996
K20-K31 Diseases of oesophagus, stomach and duodenum	0.003	0.996
R50-R69 General symptoms and signs	0.004	0.996
H90-H95 Other disorders of ear	0.003	0.996
H80-H83 Diseases of inner ear	0.003	0.996
H65-H75 Diseases of middle ear and mastoid	0.003	0.996
H60-H62 Diseases of external ear	0.003	0.996
M15-M19 Arthrosis	0.003	0.996
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.996
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.003	0.996
T79-T79 Certain early complications of trauma	0.003	0.996
T66-T78 Other and unspecified effects of external causes	0.003	0.996
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.003	0.996
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.996
T33-T35 Frostbite	0.003	0.996
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.996
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.996
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.996
T15-T19 Effects of foreign body entering through natural orifice	0.003	0.996
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.996
T00-T07 Injuries involving multiple body regions	0.003	0.996
S90-S99 Injuries to the ankle and foot	0.003	0.996
S80-S89 Injuries to the knee and lower leg	0.003	0.996
S70-S79 Injuries to the hip and thigh	0.003	0.996
S60-S69 Injuries to the wrist and hand	0.003	0.996
S50-S59 Injuries to the elbow and forearm	0.003	0.996
S40-S49 Injuries to the shoulder and upper arm	0.003	0.996
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.996
S20-S29 Injuries to the thorax	0.003	0.996
S10-S19 Injuries to the neck	0.003	0.996
S00-S09 Injuries to the head	0.003	0.996
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.996
O85-O92 Complications predominantly related to the puerperium	0.003	0.996
O80-O84 Delivery	0.003	0.996
O60-O75 Complications of labour and delivery	0.003	0.996
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.003	0.996
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.996
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.003	0.996
O00-O08 Pregnancy with abortive outcome	0.003	0.996
P90-P96 Other disorders originating in the perinatal period	0.003	0.996
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.003	0.996
P75-P78 Digestive system disorders of fetus and newborn	0.003	0.996
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.003	0.996
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.003	0.996
P35-P39 Infections specific to the perinatal period	0.003	0.996
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.003	0.996
P10-P15 Birth trauma	0.003	0.996
P05-P08 Disorders related to length of gestation and fetal growth	0.003	0.996
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.003	0.996
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.996
Q80-Q89 Other congenital malformations	0.003	0.996
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.996
Q60-Q64 Congenital malformations of the urinary system	0.003	0.996
Q50-Q56 Congenital malformations of genital organs	0.003	0.996
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.996
Q35-Q37 Cleft lip and cleft palate	0.003	0.996
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.996
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.996
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.996
Q00-Q07 Congenital malformations of the nervous system	0.003	0.996
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.003	0.996
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.996
K80 Cholelithiasis	0.003	0.996
Z54 Convalescence	0.003	0.996
Z52 Donors of organs and tissues	0.003	0.996
Z50 Care involving use of rehabilitation procedures	0.003	0.996
Z49 Care involving dialysis	0.003	0.996
Z48 Other surgical follow-up care	0.003	0.996
Z47 Other orthopaedic follow-up care	0.003	0.996
Z46 Fitting and adjustment of other devices	0.003	0.996
Z45 Adjustment and management of implanted device	0.003	0.996
Z44 Fitting and adjustment of external prosthetic device	0.003	0.996
Z43 Attention to artificial openings	0.003	0.996
Z42 Follow-up care involving plastic surgery	0.003	0.996
Z41 Procedures for purposes other than remedying health state	0.003	0.996
Z40 Prophylactic surgery	0.003	0.996
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.003	0.996
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.003	0.996
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.996
Y60-Y69 Misadventures to patients during surgical and medical care	0.003	0.996
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.996
Y35-Y36 Legal intervention and operations of war	0.003	0.996
Y10-Y34 Event of undetermined intent	0.003	0.996
Y00-Y09 Assault	0.003	0.996
X85-X99 Assault	0.003	0.996
X60-X84 Intentional self-harm	0.003	0.996
X58-X59 Accidental exposure to other and unspecified factors	0.003	0.996
X50-X57 Overexertion, travel and privation	0.003	0.996
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.996
X30-X39 Exposure to forces of nature	0.003	0.996
X20-X29 Contact with venomous animals and plants	0.003	0.996
X10-X19 Contact with heat and hot substances	0.003	0.996
X00-X09 Exposure to smoke, fire and flames	0.003	0.996
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.003	0.996
W75-W84 Other accidental threats to breathing	0.003	0.996
W65-W74 Accidental drowning and submersion	0.003	0.996
W50-W64 Exposure to animate mechanical forces	0.003	0.996
W20-W49 Exposure to inanimate mechanical forces	0.003	0.996
W00-W19 Falls	0.003	0.996
V98-V99 Other and unspecified transport accidents	0.003	0.996
V95-V97 Air and space transport accidents	0.003	0.996
V90-V94 Water transport accidents	0.003	0.996
V80-V89 Other land transport accidents	0.003	0.996
V70-V79 Bus occupant injured in transport accident	0.003	0.996
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.003	0.996
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.003	0.996
V40-V49 Car occupant injured in transport accident	0.003	0.996
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.003	0.996
V20-V29 Motorcycle rider injured in transport accident	0.003	0.996
V10-V19 Pedal cyclist injured in transport accident	0.003	0.996
V01-V09 Pedestrian injured in transport accident	0.003	0.996
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.003	0.996
K86 Other diseases of pancreas	0.003	0.996
K85 Acute pancreatitis	0.003	0.996
K83 Other diseases of biliary tract	0.003	0.996
K82 Other diseases of gallbladder	0.003	0.996
K81 Cholecystitis	0.003	0.996
G90-G99 Other disorders of the nervous system	0.003	0.996
G80-G83 Cerebral palsy and other paralytic syndromes	0.003	0.996
G70-G73 Diseases of myoneural junction and muscle	0.003	0.996
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.003	0.996
G40-G47 Episodic and paroxysmal disorders	0.003	0.996
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.996
G30-G32 Other degenerative diseases of the nervous system	0.003	0.996
G20-G26 Extrapyramidal and movement disorders	0.003	0.996
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.003	0.996
G00-G09 Inflammatory diseases of the central nervous system	0.003	0.996
J95-J99 Other diseases of the respiratory system	0.003	0.996
J90-J94 Other diseases of pleura	0.003	0.996
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.003	0.996
J80-J84 Other respiratory diseases principally affecting the interstitium	0.003	0.996
J60-J70 Lung diseases due to external agents	0.003	0.996
J30-J39 Other diseases of upper respiratory tract	0.003	0.996
J20-J22 Other acute lower respiratory infections	0.003	0.996
J09-J18 Influenza and pneumonia	0.003	0.996
J00-J06 Acute upper respiratory infections	0.003	0.996
K14 Diseases of tongue	0.003	0.996
K13 Other diseases of lip and oral mucosa	0.003	0.996
K12 Stomatitis and related lesions	0.003	0.996
K11 Diseases of salivary glands	0.003	0.996
K10 Other diseases of jaws	0.003	0.996
K09 Cysts of oral region, not elsewhere classified	0.003	0.996
K08 Other disorders of teeth and supporting structures	0.003	0.996
K07 Dentofacial anomalies [including malocclusion]	0.003	0.996
K06 Other disorders of gingiva and edentulous alveolar ridge	0.003	0.996
K05 Gingivitis and periodontal diseases	0.003	0.996
K04 Diseases of pulp and periapical tissues	0.003	0.996
K03 Other diseases of hard tissues of teeth	0.003	0.996
K02 Dental caries	0.003	0.996
K01 Embedded and impacted teeth	0.003	0.996
K00 Disorders of tooth development and eruption	0.003	0.996
K38 Other diseases of appendix	0.003	0.996
K35 Acute appendicitis	0.003	0.996
K37 Unspecified appendicitis	0.003	0.996
K36 Other appendicitis	0.003	0.996
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.003	0.996
K66 Other disorders of peritoneum	0.003	0.996
K65 Peritonitis	0.003	0.996
K77 Liver disorders in diseases classified elsewhere	0.003	0.996
K76 Other diseases of liver	0.003	0.996
K75 Other inflammatory liver diseases	0.003	0.996
K74 Fibrosis and cirrhosis of liver	0.003	0.996
K73 Chronic hepatitis, not elsewhere classified	0.003	0.996
K72 Hepatic failure, not elsewhere classified	0.003	0.996
K71 Toxic liver disease	0.003	0.996
K70 Alcoholic liver disease	0.003	0.996
K93 Disorders of other digestive organs in diseases classified elsewhere	0.003	0.996
K92 Other diseases of digestive system	0.003	0.996
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.003	0.996
K90 Intestinal malabsorption	0.003	0.996
F99-F99 Unspecified mental disorder	0.003	0.996
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.003	0.996
F80-F89 Disorders of psychological development	0.003	0.996
F70-F79 Mental retardation	0.003	0.996
F60-F69 Disorders of adult personality and behaviour	0.003	0.996
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.003	0.996
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.003	0.996
F00-F09 Organic, including symptomatic, mental disorders	0.003	0.996
I25.1 Atherosclerotic heart disease	0.003	0.996
R79 Other abnormal findings of blood chemistry	0.003	0.996
R94 Abnormal results of function studies	0.003	0.996
R93 Abnormal findings on diagnostic imaging of other body structures	0.003	0.996
R90 Abnormal findings on diagnostic imaging of central nervous system	0.003	0.996
R92 Abnormal findings on diagnostic imaging of breast	0.003	0.996
Z12 Special screening examination for neoplasms	0.003	0.996
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.003	0.996
Z30 Contraceptive management	0.003	0.996
E10-E14 Diabetes mellitus	0.003	0.996
G50-G59 Nerve, nerve root and plexus disorders	0.003	0.996
H26.8 Other specified cataract	0.003	0.996
H26.4 After-cataract	0.003	0.996
H26.3 Drug-induced cataract	0.003	0.996
H26.2 Complicated cataract	0.003	0.996
H26.1 Traumatic cataract	0.003	0.996
H26.0 Infantile, juvenile and presenile cataract	0.003	0.996
I10 Essential (primary) hypertension	0.003	0.996
Z51.9 Medical care, unspecified	0.003	0.996
Z51.8 Other specified medical care	0.003	0.996
Z51.6 Desensitisation to allergens	0.003	0.996
Z51.5 Palliative care	0.003	0.996
Z51.4 Preparatory care for treatment, not elsewhere classified	0.003	0.996
Z51.3 Blood transfusion without reported diagnosis	0.003	0.996
Z51.0 Radiotherapy session	0.003	0.996
Z11 Special screening examination for infectious and parasitic diseases	0.003	0.996
Z10 Routine general health check-up of defined subpopulation	0.003	0.996
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.003	0.996
Z04 Examination and observation for other reasons	0.003	0.996
Z03 Medical observation and evaluation for suspected diseases and conditions	0.003	0.996
Z02 Examination and encounter for administrative purposes	0.003	0.996
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.003	0.996
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.003	0.996
J40-J47 Chronic lower respiratory diseases	0.003	0.996
Z70-Z76 Persons encountering health services in other circumstances	0.003	0.996
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997
D55-D59 Haemolytic anaemias	0.003	0.997
D50-D53 Nutritional anaemias	0.003	0.997
I20.9 Angina pectoris, unspecified	0.003	0.997
R10.2 Pelvic and perineal pain	0.003	0.997
R10.0 Acute abdomen	0.003	0.997
I15 Secondary hypertension	0.003	0.997
I13 Hypertensive heart and renal disease	0.003	0.997
I12 Hypertensive renal disease	0.003	0.997
I11 Hypertensive heart disease	0.003	0.997
K43 Ventral hernia	0.003	0.997
N20-N23 Urolithiasis	0.003	0.997
I84.9 Unspecified haemorrhoids without complication	0.003	0.997
R11 Nausea and vomiting	0.003	0.997
F41 Other anxiety disorders	0.003	0.997
K57 Diverticular disease of intestine	0.003	0.997
I84.6 Residual haemorrhoidal skin tags	0.003	0.997
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.003	0.997
R04 Haemorrhage from respiratory passages	0.003	0.997
R03 Abnormal blood-pressure reading, without diagnosis	0.003	0.997
R01 Cardiac murmurs and other cardiac sounds	0.003	0.997
R00 Abnormalities of heart beat	0.003	0.997
R05 Cough	0.003	0.997
R02 Gangrene, not elsewhere classified	0.003	0.997
I02 Rheumatic chorea	0.003	0.997
I01 Rheumatic fever with heart involvement	0.003	0.997
I00 Rheumatic fever without mention of heart involvement	0.003	0.997
I09 Other rheumatic heart diseases	0.003	0.997
I08 Multiple valve diseases	0.003	0.997
I07 Rheumatic tricuspid valve diseases	0.003	0.997
I06 Rheumatic aortic valve diseases	0.003	0.997
I05 Rheumatic mitral valve diseases	0.003	0.997
I28 Other diseases of pulmonary vessels	0.003	0.997
I27 Other pulmonary heart diseases	0.003	0.997
I26 Pulmonary embolism	0.003	0.997
I52 Other heart disorders in diseases classified elsewhere	0.003	0.997
I51 Complications and ill-defined descriptions of heart disease	0.003	0.997
I50 Heart failure	0.003	0.997
I49 Other cardiac arrhythmias	0.003	0.997
I48 Atrial fibrillation and flutter	0.003	0.997
I47 Paroxysmal tachycardia	0.003	0.997
I46 Cardiac arrest	0.003	0.997
I45 Other conduction disorders	0.003	0.997
I44 Atrioventricular and left bundle-branch block	0.003	0.997
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997
I42 Cardiomyopathy	0.003	0.997
I41 Myocarditis in diseases classified elsewhere	0.003	0.997
I40 Acute myocarditis	0.003	0.997
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.003	0.997
I37 Pulmonary valve disorders	0.003	0.997
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997
I35 Nonrheumatic aortic valve disorders	0.003	0.997
I34 Nonrheumatic mitral valve disorders	0.003	0.997
I33 Acute and subacute endocarditis	0.003	0.997
I32 Pericarditis in diseases classified elsewhere	0.003	0.997
I31 Other diseases of pericardium	0.003	0.997
I30 Acute pericarditis	0.003	0.997
I38 Endocarditis, valve unspecified	0.003	0.997
I69 Sequelae of cerebrovascular disease	0.003	0.997
I68 Cerebrovascular disorders in diseases classified elsewhere	0.003	0.997
I67 Other cerebrovascular diseases	0.003	0.997
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.003	0.997
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.003	0.997
I63 Cerebral infarction	0.003	0.997
I62 Other nontraumatic intracranial haemorrhage	0.003	0.997
I61 Intracerebral haemorrhage	0.003	0.997
I60 Subarachnoid haemorrhage	0.003	0.997
I64 Stroke, not specified as haemorrhage or infarction	0.003	0.997
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.997
I78 Diseases of capillaries	0.003	0.997
I77 Other disorders of arteries and arterioles	0.003	0.997
I74 Arterial embolism and thrombosis	0.003	0.997
I73 Other peripheral vascular diseases	0.003	0.997
I72 Other aneurysm	0.003	0.997
I71 Aortic aneurysm and dissection	0.003	0.997
I70 Atherosclerosis	0.003	0.997
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997
I95 Hypotension	0.003	0.997
I99 Other and unspecified disorders of circulatory system	0.003	0.997
K62 Other diseases of anus and rectum	0.003	0.997
M79 Other soft tissue disorders, not elsewhere classified	0.003	0.997
I20.8 Other forms of angina pectoris	0.003	0.997
I20.1 Angina pectoris with documented spasm	0.003	0.997
R78 Findings of drugs and other substances, not normally found in blood	0.003	0.997
R77 Other abnormalities of plasma proteins	0.003	0.997
R76 Other abnormal immunological findings in serum	0.003	0.997
R74 Abnormal serum enzyme levels	0.003	0.997
R73 Elevated blood glucose level	0.003	0.997
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.003	0.997
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.003	0.997
R72 Abnormality of white blood cells, not elsewhere classified	0.003	0.997
R71 Abnormality of red blood cells	0.003	0.997
Z53 Persons encountering health services for specifie procedures, not carried out	0.003	0.997

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations