TreeWAS – Variant ID: rs1997352

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.002	0.997
M15-M19 Arthrosis	0.002	0.997
# Top node	0.002	0.997
M17 Gonarthrosis [arthrosis of knee]	0.002	0.998
M17.9 Gonarthrosis, unspecified	0.002	0.998
M20-M25 Other joint disorders	0.002	0.998
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998
Chapter II Neoplasms	0.002	0.998
M16 Coxarthrosis [arthrosis of hip]	0.002	0.998
M17.1 Other primary gonarthrosis	0.002	0.998
M70-M79 Other soft tissue disorders	0.002	0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998
Chapter XI Diseases of the digestive system	0.002	0.998
M05-M14 Inflammatory polyarthropathies	0.002	0.998
Chapter XX External causes of morbidity and mortality	0.002	0.998
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998
Chapter V Mental and behavioural disorders	0.002	0.998
Chapter IX Diseases of the circulatory system	0.002	0.998
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.002	0.998
M91-M94 Chondropathies	0.002	0.998
M86-M90 Other osteopathies	0.002	0.998
M80-M85 Disorders of bone density and structure	0.002	0.998
M65-M68 Disorders of synovium and tendon	0.002	0.998
M60-M63 Disorders of muscles	0.002	0.998
M50-M54 Other dorsopathies	0.002	0.998
M45-M49 Spondylopathies	0.002	0.998
M40-M43 Deforming dorsopathies	0.002	0.998
M00-M03 Infectious arthropathies	0.002	0.998
Chapter XV Pregnancy, childbirth and the puerperium	0.002	0.998
M18 Arthrosis of first carpometacarpal joint	0.002	0.998
M15 Polyarthrosis	0.002	0.998
Chapter XXI Factors influencing health status and contact with health services	0.002	0.998
Chapter VII Diseases of the eye and adnexa	0.002	0.998
E65-E68 Obesity and other hyperalimentation	0.002	0.998
Chapter XXII Codes for special purposes	0.002	0.998
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998
Chapter XVI Certain conditions originating in the perinatal period	0.002	0.998
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998
Chapter VI Diseases of the nervous system	0.002	0.998
M16.9 Coxarthrosis, unspecified	0.002	0.998
M17.5 Other secondary gonarthrosis	0.002	0.998
M17.4 Other secondary gonarthrosis, bilateral	0.002	0.998
M17.3 Other posttraumatic gonarthrosis	0.002	0.998
M17.2 Posttraumatic gonarthrosis, bilateral	0.002	0.998
M17.0 Primary gonarthrosis, bilateral	0.002	0.998
M19 Other arthrosis	0.002	0.998
Chapter I Certain infectious and parasitic diseases	0.002	0.998
M23 Internal derangement of knee	0.002	0.998
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.002	0.998
Chapter XII Diseases of the skin and subcutaneous tissue	0.002	0.998
K20-K31 Diseases of oesophagus, stomach and duodenum	0.002	0.998
C50-C50 Malignant neoplasm of breast	0.002	0.998
E70-E90 Metabolic disorders	0.002	0.998
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.002	0.998
Chapter X Diseases of the respiratory system	0.002	0.998
C60-C63 Malignant neoplasms of male genital organs	0.002	0.998
E66 Obesity	0.002	0.998
M20 Acquired deformities of fingers and toes	0.002	0.998
K21 Gastro-oesophageal reflux disease	0.002	0.998
M25 Other joint disorders, not elsewhere classified	0.002	0.998
E66.9 Obesity, unspecified	0.002	0.998
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.002	0.998
M35 Other systemic involvement of connective tissue	0.002	0.998
M34 Systemic sclerosis	0.002	0.998
M33 Dermatopolymyositis	0.002	0.998
M32 Systemic lupus erythematosus	0.002	0.998
M31 Other necrotising vasculopathies	0.002	0.998
M30 Polyarteritis nodosa and related conditions	0.002	0.998
M24 Other specific joint derangements	0.002	0.998
M22 Disorders of patella	0.002	0.998
M21 Other acquired deformities of limbs	0.002	0.998
M75 Shoulder lesions	0.002	0.998
D60-D64 Aplastic and other anaemias	0.002	0.998
E50-E64 Other nutritional deficiencies	0.002	0.998
E40-E46 Malnutrition	0.002	0.998
E20-E35 Disorders of other endocrine glands	0.002	0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998
E00-E07 Disorders of thyroid gland	0.002	0.998
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.002	0.998
M16.7 Other secondary coxarthrosis	0.002	0.998
M16.6 Other secondary coxarthrosis, bilateral	0.002	0.998
M16.5 Other posttraumatic coxarthrosis	0.002	0.998
M16.4 Posttraumatic coxarthrosis, bilateral	0.002	0.998
M16.3 Other dysplastic coxarthrosis	0.002	0.998
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.002	0.998
M16.1 Other primary coxarthrosis	0.002	0.998
M16.0 Primary coxarthrosis, bilateral	0.002	0.998
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998
D00-D09 In situ neoplasms	0.002	0.998
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.002	0.998
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.002	0.998
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998
C64-C68 Malignant neoplasms of urinary tract	0.002	0.998
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.002	0.998
C40-C41 Malignant neoplasms of bone and articular cartilage	0.002	0.998
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.002	0.998
C15-C26 Malignant neoplasms of digestive organs	0.002	0.998
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998
D50-D53 Nutritional anaemias	0.002	0.998
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.002	0.998
D10-D36 Benign neoplasms	0.002	0.998
C43-C44 Melanoma and other malignant neoplasms of skin	0.002	0.998
I10-I15 Hypertensive diseases	0.002	0.998
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.002	0.998
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.002	0.998
M79 Other soft tissue disorders, not elsewhere classified	0.002	0.998
M77 Other enthesopathies	0.002	0.998
M76 Enthesopathies of lower limb, excluding foot	0.002	0.998
M73 Soft tissue disorders in diseases classified elsewhere	0.002	0.998
M72 Fibroblastic disorders	0.002	0.998
M71 Other bursopathies	0.002	0.998
M70 Soft tissue disorders related to use, overuse and pressure	0.002	0.998
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998
E10-E14 Diabetes mellitus	0.002	0.998
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998
I20-I25 Ischaemic heart diseases	0.002	0.998
O60-O75 Complications of labour and delivery	0.002	0.998
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.002	0.998
M23.2 Derangement of meniscus due to old tear or injury	0.002	0.998
M13 Other arthritis	0.002	0.998
M54 Dorsalgia	0.002	0.998
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998
D55-D59 Haemolytic anaemias	0.002	0.998
I60-I69 Cerebrovascular diseases	0.002	0.998
S50-S59 Injuries to the elbow and forearm	0.002	0.998
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998
C79 Secondary malignant neoplasm of other sites	0.002	0.998
M14 Arthropathies in other diseases classified elsewhere	0.002	0.998
M12 Other specific arthropathies	0.002	0.998
M11 Other crystal arthropathies	0.002	0.998
M09 Juvenile arthritis in diseases classified elsewhere	0.002	0.998
M08 Juvenile arthritis	0.002	0.998
M07 Psoriatic and enteropathic arthropathies	0.002	0.998
M06 Other rheumatoid arthritis	0.002	0.998
M05 Seropositive rheumatoid arthritis	0.002	0.998
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998
I30-I52 Other forms of heart disease	0.002	0.998
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998
I05-I09 Chronic rheumatic heart diseases	0.002	0.998
I00-I02 Acute rheumatic fever	0.002	0.998
K70-K77 Diseases of liver	0.002	0.998
K65-K67 Diseases of peritoneum	0.002	0.998
K35-K38 Diseases of appendix	0.002	0.998
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.002	0.998
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998
T79-T79 Certain early complications of trauma	0.002	0.998
T66-T78 Other and unspecified effects of external causes	0.002	0.998
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998
T33-T35 Frostbite	0.002	0.998
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.002	0.998
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.998
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.998
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998
T00-T07 Injuries involving multiple body regions	0.002	0.998
S90-S99 Injuries to the ankle and foot	0.002	0.998
S80-S89 Injuries to the knee and lower leg	0.002	0.998
S70-S79 Injuries to the hip and thigh	0.002	0.998
S60-S69 Injuries to the wrist and hand	0.002	0.998
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998
S20-S29 Injuries to the thorax	0.002	0.998
S10-S19 Injuries to the neck	0.002	0.998
S00-S09 Injuries to the head	0.002	0.998
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.002	0.998
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.002	0.998
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.002	0.998
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998
Y35-Y36 Legal intervention and operations of war	0.002	0.998
Y10-Y34 Event of undetermined intent	0.002	0.998
Y00-Y09 Assault	0.002	0.998
X85-X99 Assault	0.002	0.998
X60-X84 Intentional self-harm	0.002	0.998
X58-X59 Accidental exposure to other and unspecified factors	0.002	0.998
X50-X57 Overexertion, travel and privation	0.002	0.998
X40-X49 Accidental poisoning by and exposure to noxious substances	0.002	0.998
X30-X39 Exposure to forces of nature	0.002	0.998
X20-X29 Contact with venomous animals and plants	0.002	0.998
X10-X19 Contact with heat and hot substances	0.002	0.998
X00-X09 Exposure to smoke, fire and flames	0.002	0.998
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.002	0.998
W75-W84 Other accidental threats to breathing	0.002	0.998
W65-W74 Accidental drowning and submersion	0.002	0.998
W50-W64 Exposure to animate mechanical forces	0.002	0.998
W20-W49 Exposure to inanimate mechanical forces	0.002	0.998
W00-W19 Falls	0.002	0.998
V98-V99 Other and unspecified transport accidents	0.002	0.998
V95-V97 Air and space transport accidents	0.002	0.998
V90-V94 Water transport accidents	0.002	0.998
V80-V89 Other land transport accidents	0.002	0.998
V70-V79 Bus occupant injured in transport accident	0.002	0.998
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.002	0.998
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.002	0.998
V40-V49 Car occupant injured in transport accident	0.002	0.998
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.002	0.998
V20-V29 Motorcycle rider injured in transport accident	0.002	0.998
V10-V19 Pedal cyclist injured in transport accident	0.002	0.998
V01-V09 Pedestrian injured in transport accident	0.002	0.998
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.002	0.998
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.002	0.998
M02 Reactive arthropathies	0.002	0.998
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.002	0.998
M00 Pyogenic arthritis	0.002	0.998
M10 Gout	0.002	0.998
M43 Other deforming dorsopathies	0.002	0.998
M42 Spinal osteochondrosis	0.002	0.998
M41 Scoliosis	0.002	0.998
M40 Kyphosis and lordosis	0.002	0.998
M49 Spondylopathies in diseases classified elsewhere	0.002	0.998
M48 Other spondylopathies	0.002	0.998
M47 Spondylosis	0.002	0.998
M46 Other inflammatory spondylopathies	0.002	0.998
M45 Ankylosing spondylitis	0.002	0.998
M53 Other dorsopathies, not elsewhere classified	0.002	0.998
M50 Cervical disk disorders	0.002	0.998
M63 Disorders of muscle in diseases classified elsewhere	0.002	0.998
M62 Other disorders of muscle	0.002	0.998
M61 Calcification and ossification of muscle	0.002	0.998
M60 Myositis	0.002	0.998
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.002	0.998
M67 Other disorders of synovium and tendon	0.002	0.998
M66 Spontaneous rupture of synovium and tendon	0.002	0.998
M65 Synovitis and tenosynovitis	0.002	0.998
M85 Other disorders of bone density and structure	0.002	0.998
M84 Disorders of continuity of bone	0.002	0.998
M83 Adult osteomalacia	0.002	0.998
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998
M81 Osteoporosis without pathological fracture	0.002	0.998
M80 Osteoporosis with pathological fracture	0.002	0.998
M90 Osteopathies in diseases classified elsewhere	0.002	0.998
M89 Other disorders of bone	0.002	0.998
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998
M87 Osteonecrosis	0.002	0.998
M86 Osteomyelitis	0.002	0.998
M94 Other disorders of cartilage	0.002	0.998
M93 Other osteochondropathies	0.002	0.998
M92 Other juvenile osteochondrosis	0.002	0.998
M91 Juvenile osteochondrosis of hip and pelvis	0.002	0.998
M99 Biomechanical lesions, not elsewhere classified	0.002	0.998
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998
F99-F99 Unspecified mental disorder	0.002	0.998
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.002	0.998
F80-F89 Disorders of psychological development	0.002	0.998
F70-F79 Mental retardation	0.002	0.998
F60-F69 Disorders of adult personality and behaviour	0.002	0.998
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998
F40-F48 Neurotic, stress-related and somatoform disorders	0.002	0.998
F30-F39 Mood [affective] disorders	0.002	0.998
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998
H25-H28 Disorders of lens	0.002	0.998
K50-K52 Noninfective enteritis and colitis	0.002	0.998
K40-K46 Hernia	0.002	0.998
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998
O85-O92 Complications predominantly related to the puerperium	0.002	0.998
O80-O84 Delivery	0.002	0.998
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998
O00-O08 Pregnancy with abortive outcome	0.002	0.998
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.002	0.998
C50 Malignant neoplasm of breast	0.002	0.998
K30 Dyspepsia	0.002	0.998
K90-K93 Other diseases of the digestive system	0.002	0.998
Z70-Z76 Persons encountering health services in other circumstances	0.002	0.998
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.002	0.998
Chapter XIV Diseases of the genitourinary system	0.001	0.998
M15.9 Polyarthrosis, unspecified	0.001	0.998
M15.0 Primary generalised (osteo)arthrosis	0.001	0.998
M15.8 Other polyarthrosis	0.001	0.998
M15.4 Erosive (osteo)arthrosis	0.001	0.998
M15.3 Secondary multiple arthrosis	0.001	0.998
M15.2 Bouchard's nodes (with arthropathy)	0.001	0.998
M15.1 Heberden's nodes (with arthropathy)	0.001	0.998
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.001	0.998
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.001	0.998
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.001	0.998
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.001	0.998
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.001	0.998
M18.1 Other primary arthrosis of first carpometacarpal joint	0.001	0.998
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.001	0.998
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.002	0.998
E67 Other hyperalimentation	0.001	0.998
E68 Sequelae of hyperalimentation	0.001	0.998
E65 Localised adiposity	0.001	0.998
M51 Other intervertebral disk disorders	0.001	0.998
G90-G99 Other disorders of the nervous system	0.002	0.998
G80-G83 Cerebral palsy and other paralytic syndromes	0.002	0.998
G70-G73 Diseases of myoneural junction and muscle	0.002	0.998
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.998
G40-G47 Episodic and paroxysmal disorders	0.002	0.998
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998
G30-G32 Other degenerative diseases of the nervous system	0.002	0.998
G20-G26 Extrapyramidal and movement disorders	0.002	0.998
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.002	0.998
G00-G09 Inflammatory diseases of the central nervous system	0.002	0.998
H55-H59 Other disorders of eye and adnexa	0.002	0.998
H53-H54 Visual disturbances and blindness	0.002	0.998
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998
H46-H48 Disorders of optic nerve and visual pathways	0.002	0.998
H43-H45 Disorders of vitreous body and globe	0.002	0.998
H40-H42 Glaucoma	0.002	0.998
H30-H36 Disorders of choroid and retina	0.002	0.998
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998
H10-H13 Disorders of conjunctiva	0.002	0.998
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.002	0.998
H90-H95 Other disorders of ear	0.002	0.998
H80-H83 Diseases of inner ear	0.002	0.998
H65-H75 Diseases of middle ear and mastoid	0.002	0.998
H60-H62 Diseases of external ear	0.002	0.998
P90-P96 Other disorders originating in the perinatal period	0.002	0.998
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.002	0.998
P75-P78 Digestive system disorders of fetus and newborn	0.002	0.998
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.002	0.998
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.002	0.998
P35-P39 Infections specific to the perinatal period	0.002	0.998
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.002	0.998
P10-P15 Birth trauma	0.002	0.998
P05-P08 Disorders related to length of gestation and fetal growth	0.002	0.998
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.002	0.998
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998
Q80-Q89 Other congenital malformations	0.002	0.998
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998
Q50-Q56 Congenital malformations of genital organs	0.002	0.998
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998
Q35-Q37 Cleft lip and cleft palate	0.002	0.998
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998
Z00-Z13 Persons encountering health services for examination and investigation	0.002	0.998
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.002	0.998
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.002	0.998
C61 Malignant neoplasm of prostate	0.002	0.998
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.002	0.998
G50-G59 Nerve, nerve root and plexus disorders	0.001	0.998
Z40-Z54 Persons encountering health services for specific procedures and health care	0.002	0.998
M19.8 Other specified arthrosis	0.001	0.998
M19.2 Other secondary arthrosis	0.001	0.998
M19.1 Posttraumatic arthrosis of other joints	0.001	0.998
M19.0 Primary arthrosis of other joints	0.001	0.998
M20.1 Hallux valgus (acquired)	0.001	0.998
B99-B99 Other infectious diseases	0.001	0.998
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.998
B85-B89 Pediculosis, acariasis and other infestations	0.001	0.998
B65-B83 Helminthiases	0.001	0.998
B50-B64 Protozoal diseases	0.001	0.998
B35-B49 Mycoses	0.001	0.998
B25-B34 Other viral diseases	0.001	0.998
B20-B24 Human immunodeficiency virus [HIV] disease	0.001	0.998
B15-B19 Viral hepatitis	0.001	0.998
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.001	0.998
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.001	0.998
A80-A89 Viral infections of the central nervous system	0.001	0.998
A75-A79 Rickettsioses	0.001	0.998
A70-A74 Other diseases caused by chlamydiae	0.001	0.998
A65-A69 Other spirochaetal diseases	0.001	0.998
A50-A64 Infections with a predominantly sexual mode of transmission	0.001	0.998
A20-A28 Certain zoonotic bacterial diseases	0.001	0.998
A15-A19 Tuberculosis	0.001	0.998
A00-A09 Intestinal infectious diseases	0.001	0.998
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.001	0.998
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.002	0.998
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.002	0.998
M23.9 Internal derangement of knee, unspecified	0.001	0.998
M23.8 Other internal derangements of knee	0.001	0.998
M23.6 Other spontaneous disruption of ligament(s) of knee	0.001	0.998
M23.5 Chronic instability of knee	0.001	0.998
M23.4 Loose body in knee	0.001	0.998
M23.3 Other meniscus derangements	0.001	0.998
M23.1 Discoid meniscus (congenital)	0.001	0.998
M23.0 Cystic meniscus	0.001	0.998
C80 Malignant neoplasm without specification of site	0.001	0.998
C76 Malignant neoplasm of other and ill-defined sites	0.001	0.998
K22 Other diseases of oesophagus	0.001	0.998
L80-L99 Other disorders of the skin and subcutaneous tissue	0.001	0.998
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.001	0.998
L50-L54 Urticaria and erythema	0.001	0.998
L40-L45 Papulosquamous disorders	0.001	0.998
L20-L30 Dermatitis and eczema	0.001	0.998
L10-L14 Bullous disorders	0.001	0.998
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.002	0.998
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.001	0.998
D64 Other anaemias	0.001	0.998
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.001	0.998
E88 Other metabolic disorders	0.001	0.998
E85 Amyloidosis	0.001	0.998
E84 Cystic fibrosis	0.001	0.998
E83 Disorders of mineral metabolism	0.001	0.998
E80 Disorders of porphyrin and bilirubin metabolism	0.001	0.998
E79 Disorders of purine and pyrimidine metabolism	0.001	0.998
E77 Disorders of glycoprotein metabolism	0.001	0.998
E76 Disorders of glycosaminoglycan metabolism	0.001	0.998
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.001	0.998
E74 Other disorders of carbohydrate metabolism	0.001	0.998
E73 Lactose intolerance	0.001	0.998
E72 Other disorders of amino-acid metabolism	0.001	0.998
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.998
E70 Disorders of aromatic amino-acid metabolism	0.001	0.998
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.998
E86 Volume depletion	0.001	0.998
K28 Gastrojejunal ulcer	0.001	0.998
K27 Peptic ulcer, site unspecified	0.001	0.998
K26 Duodenal ulcer	0.001	0.998
K25 Gastric ulcer	0.001	0.998
K23 Disorders of oesophagus in diseases classified elsewhere	0.001	0.998
Z92 Personal history of medical treatment	0.002	0.998
B95-B98 Bacterial, viral and other infectious agents	0.001	0.998
A30-A49 Other bacterial diseases	0.001	0.998
J09-J18 Influenza and pneumonia	0.001	0.998
L60-L75 Disorders of skin appendages	0.001	0.998
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.001	0.998
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.001	0.998
M75.1 Rotator cuff syndrome	0.001	0.998
C63 Malignant neoplasm of other and unspecified male genital organs	0.001	0.998
C62 Malignant neoplasm of testis	0.001	0.998
C60 Malignant neoplasm of penis	0.001	0.998
E87 Other disorders of fluid, electrolyte and acid-base balance	0.001	0.998
F17 Mental and behavioural disorders due to use of tobacco	0.001	0.998
J95-J99 Other diseases of the respiratory system	0.001	0.998
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.001	0.998
J80-J84 Other respiratory diseases principally affecting the interstitium	0.001	0.998
J60-J70 Lung diseases due to external agents	0.001	0.998
J00-J06 Acute upper respiratory infections	0.001	0.998
K55-K64 Other diseases of intestines	0.001	0.998
L00-L08 Infections of the skin and subcutaneous tissue	0.001	0.998
R95-R99 Ill-defined and unknown causes of mortality	0.001	0.998
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.001	0.998
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.001	0.998
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.001	0.998
R47-R49 Symptoms and signs involving speech and voice	0.001	0.998
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.001	0.998
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.998
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.001	0.998
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998
E66.8 Other obesity	0.001	0.998
E66.2 Extreme obesity with alveolar hypoventilation	0.001	0.998
E66.1 Drug-induced obesity	0.001	0.998
E66.0 Obesity due to excess calories	0.001	0.998
E78.0 Pure hypercholesterolaemia	0.001	0.998
M19.9 Arthrosis, unspecified	0.001	0.998
M20.6 Acquired deformity of toe(s), unspecified	0.001	0.998
M20.5 Other deformities of toe(s) (acquired)	0.001	0.998
M20.4 Other hammer toe(s) (acquired)	0.001	0.998
M20.3 Other deformity of hallux (acquired)	0.001	0.998
M20.2 Hallux rigidus	0.001	0.998
M20.0 Deformity of finger(s)	0.001	0.998
D50 Iron deficiency anaemia	0.001	0.998
T81 Complications of procedures, not elsewhere classified	0.001	0.998
J90-J94 Other diseases of pleura	0.001	0.998
J40-J47 Chronic lower respiratory diseases	0.001	0.998
J30-J39 Other diseases of upper respiratory tract	0.001	0.998
R30-R39 Symptoms and signs involving the urinary system	0.001	0.998
M25.5 Pain in joint	0.001	0.998
M75.4 Impingement syndrome of shoulder	0.001	0.998
I25 Chronic ischaemic heart disease	0.001	0.998
K31 Other diseases of stomach and duodenum	0.001	0.998
K29 Gastritis and duodenitis	0.001	0.998
K80 Cholelithiasis	0.001	0.998
M21.9 Acquired deformity of limb, unspecified	0.001	0.998
M21.8 Other specified acquired deformities of limbs	0.001	0.998
M21.7 Unequal limb length (acquired)	0.001	0.998
M21.6 Other acquired deformities of ankle and foot	0.001	0.998
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.001	0.998
M21.4 Flat foot [pes planus] (acquired)	0.001	0.998
M21.3 Wrist or foot drop (acquired)	0.001	0.998
M21.2 Flexion deformity	0.001	0.998
M21.1 Varus deformity, not elsewhere classified	0.001	0.998
M21.0 Valgus deformity, not elsewhere classified	0.001	0.998
M22.1 Recurrent subluxation of patella	0.001	0.998
M22.9 Disorder of patella, unspecified	0.001	0.998
M22.8 Other disorders of patella	0.001	0.998
M22.4 Chondromalacia patellae	0.001	0.998
M22.3 Other derangements of patella	0.001	0.998
M22.2 Patellofemoral disorders	0.001	0.998
M22.0 Recurrent dislocation of patella	0.001	0.998
M24.9 Joint derangement, unspecified	0.001	0.998
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.998
M24.7 Protrusio acetabuli	0.001	0.998
M24.6 Ankylosis of joint	0.001	0.998
M24.5 Contracture of joint	0.001	0.998
M24.4 Recurrent dislocation and subluxation of joint	0.001	0.998
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.998
M24.2 Disorder of ligament	0.001	0.998
M24.1 Other articular cartilage disorders	0.001	0.998
M24.0 Loose body in joint	0.001	0.998
M25.9 Joint disorder, unspecified	0.001	0.998
M25.8 Other specified joint disorders	0.001	0.998
M25.7 Osteophyte	0.001	0.998
M25.6 Stiffness of joint, not elsewhere classified	0.001	0.998
M25.4 Effusion of joint	0.001	0.998
M25.3 Other instability of joint	0.001	0.998

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations