TreeWAS – Variant ID: rs2233975

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
E10.9 Without complications	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
Chapter VII Diseases of the eye and adnexa	0.991	0.009
D10-D36 Benign neoplasms	0.989	0.011
Chapter VI Diseases of the nervous system	0.989	0.011
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.989	0.011
C43-C44 Melanoma and other malignant neoplasms of skin	0.988	0.012
E10.3 With ophthalmic complications	0.985	0.015
H30-H36 Disorders of choroid and retina	0.984	0.016
C50-C50 Malignant neoplasm of breast	0.975	0.025
H36 Retinal disorders in diseases classified elsewhere	0.973	0.027
Chapter I Certain infectious and parasitic diseases	0.971	0.029
C44 Other malignant neoplasms of skin	0.970	0.030
G35-G37 Demyelinating diseases of the central nervous system	0.970	0.030
D12.5 Sigmoid colon	0.969	0.031
H36.0 Diabetic retinopathy	0.966	0.034
S40-S49 Injuries to the shoulder and upper arm	0.965	0.035
C50 Malignant neoplasm of breast	0.958	0.042
G35 Multiple sclerosis	0.956	0.044
Chapter XXI Factors influencing health status and contact with health services	0.944	0.056
S42 Fracture of shoulder and upper arm	0.939	0.061
Chapter XI Diseases of the digestive system	0.938	0.062
D12.6 Colon, unspecified	0.928	0.072
C44.1 Skin of eyelid, including canthus	0.925	0.075
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.924	0.076
S60-S69 Injuries to the wrist and hand	0.923	0.077
D12.2 Ascending colon	0.923	0.077
K62.1 Rectal polyp	0.920	0.080
A00-A09 Intestinal infectious diseases	0.919	0.081
K55-K64 Other diseases of intestines	0.918	0.082
K62 Other diseases of anus and rectum	0.914	0.086
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.914	0.086
C15-C26 Malignant neoplasms of digestive organs	0.913	0.087
E10.4 With neurological complications	0.911	0.089
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.909	0.091
Z85 Personal history of malignant neoplasm	0.909	0.091
T36-T50 Poisoning by drugs, medicaments and biological substances	0.904	0.096
G50-G59 Nerve, nerve root and plexus disorders	0.900	0.100
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.898	0.102
E10.1 With ketoacidosis	0.896	0.104
C50.1 Central portion of breast	0.894	0.106
D37-D48 Neoplasms of uncertain or unknown behaviour	0.889	0.111
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.888	0.112
Chapter V Mental and behavioural disorders	0.888	0.112
A04 Other bacterial intestinal infections	0.882	0.118
H25-H28 Disorders of lens	0.880	0.120
C44.7 Skin of lower limb, including hip	0.877	0.122
C50.9 Breast, unspecified	0.876	0.124
K90-K93 Other diseases of the digestive system	0.871	0.129
Z90 Acquired absence of organs, not elsewhere classified	0.868	0.132
S50-S59 Injuries to the elbow and forearm	0.868	0.132
E14 Unspecified diabetes mellitus	0.864	0.136
C64-C68 Malignant neoplasms of urinary tract	0.860	0.140
K70-K77 Diseases of liver	0.857	0.143
C43 Malignant melanoma of skin	0.854	0.146
Z85.3 Personal history of malignant neoplasm of breast	0.854	0.146
K90 Intestinal malabsorption	0.846	0.154
S42.0 Fracture of clavicle	0.846	0.154
T66-T78 Other and unspecified effects of external causes	0.842	0.158
Chapter IX Diseases of the circulatory system	0.840	0.160
D12.3 Transverse colon	0.840	0.160
G56 Mononeuropathies of upper limb	0.832	0.168
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.832	0.168
K90.0 Coeliac disease	0.829	0.171
S42.2 Fracture of upper end of humerus	0.824	0.176
S20-S29 Injuries to the thorax	0.824	0.176
C50.4 Upper-outer quadrant of breast	0.822	0.178
D12.4 Descending colon	0.821	0.179
Z00-Z13 Persons encountering health services for examination and investigation	0.817	0.183
C44.5 Skin of trunk	0.817	0.183
Z90.1 Acquired absence of breast(s)	0.813	0.187
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.812	0.188
S60 Superficial injury of wrist and hand	0.811	0.189
D36 Benign neoplasm of other and unspecified sites	0.810	0.190
Chapter VIII Diseases of the ear and mastoid process	0.808	0.192
E16 Other disorders of pancreatic internal secretion	0.808	0.192
E10.5 With peripheral circulatory complications	0.807	0.193
H35 Other retinal disorders	0.806	0.194
Z85.5 Personal history of malignant neoplasm of urinary tract	0.805	0.195
B35-B49 Mycoses	0.800	0.200
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.798	0.202
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.798	0.202
E05 Thyrotoxicosis [hyperthyroidism]	0.797	0.203
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.795	0.205
S80-S89 Injuries to the knee and lower leg	0.795	0.205
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.795	0.205
C15 Malignant neoplasm of oesophagus	0.794	0.206
S42.1 Fracture of scapula	0.794	0.206
A04.8 Other specified bacterial intestinal infections	0.791	0.209
K63 Other diseases of intestine	0.791	0.209
A30-A49 Other bacterial diseases	0.790	0.210
T81 Complications of procedures, not elsewhere classified	0.790	0.210
S00-S09 Injuries to the head	0.788	0.212
H34 Retinal vascular occlusions	0.786	0.214
H26 Other cataract	0.784	0.216
I30-I52 Other forms of heart disease	0.783	0.217
A08 Viral and other specified intestinal infections	0.783	0.217
T88 Other complications of surgical and medical care, not elsewhere classified	0.783	0.217
E07 Other disorders of thyroid	0.783	0.217
S42.00 Fracture of clavicle (closed)	0.779	0.221
A04.7 Enterocolitis due to Clostridium difficile	0.777	0.223
Z02 Examination and encounter for administrative purposes	0.775	0.225
D26 Other benign neoplasms of uterus	0.773	0.227
H43-H45 Disorders of vitreous body and globe	0.772	0.228
Z08 Follow-up examination after treatment for malignant neoplasm	0.772	0.228
C50.3 Lower-inner quadrant of breast	0.770	0.230
E20-E35 Disorders of other endocrine glands	0.769	0.231
C44.4 Skin of scalp and neck	0.768	0.232
K55 Vascular disorders of intestine	0.768	0.232
Z95 Presence of cardiac and vascular implants and grafts	0.766	0.234
D32 Benign neoplasm of meninges	0.765	0.235
K62.3 Rectal prolapse	0.764	0.236
Chapter XX External causes of morbidity and mortality	0.763	0.237
Z91 Personal history of risk-factors, not elsewhere classified	0.761	0.239
H55-H59 Other disorders of eye and adnexa	0.760	0.240
C44.0 Skin of lip	0.759	0.241
G30-G32 Other degenerative diseases of the nervous system	0.757	0.243
E14.9 Without complications	0.756	0.244
C51-C58 Malignant neoplasms of female genital organs	0.754	0.245
D21 Other benign neoplasms of connective and other soft tissue	0.754	0.246
D24 Benign neoplasm of breast	0.753	0.247
D10 Benign neoplasm of mouth and pharynx	0.752	0.248
Z90.5 Acquired absence of kidney	0.752	0.248
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.752	0.248
E16.2 Hypoglycaemia, unspecified	0.751	0.249
G80-G83 Cerebral palsy and other paralytic syndromes	0.750	0.250
S52 Fracture of forearm	0.747	0.253
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.747	0.253
D14 Benign neoplasm of middle ear and respiratory system	0.746	0.254
K70 Alcoholic liver disease	0.746	0.254
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.746	0.254
F30-F39 Mood [affective] disorders	0.746	0.254
Z02.8 Other examinations for administrative purposes	0.745	0.255
C43.4 Malignant melanoma of scalp and neck	0.745	0.255
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.744	0.256
Chapter XXII Codes for special purposes	0.743	0.256
S42.20 Fracture of upper end of humerus (closed)	0.742	0.258
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.741	0.259
K63.5 Polyp of colon	0.738	0.262
T79-T79 Certain early complications of trauma	0.738	0.262
K35-K38 Diseases of appendix	0.736	0.264
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.736	0.264
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.735	0.264
T83.1 Mechanical complication of other urinary devices and implants	0.735	0.265
D12.7 Rectosigmoid junction	0.734	0.266
D00-D09 In situ neoplasms	0.734	0.266
S66 Injury of muscle and tendon at wrist and hand level	0.732	0.267
G56.0 Carpal tunnel syndrome	0.731	0.269
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.731	0.269
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.730	0.270
T78 Adverse effects, not elsewhere classified	0.728	0.271
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.727	0.273
G51 Facial nerve disorders	0.724	0.275
C66 Malignant neoplasm of ureter	0.723	0.277
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.722	0.278
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.721	0.279
G56.2 Lesion of ulnar nerve	0.719	0.281
D12.8 Rectum	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E13 Other specified diabetes mellitus	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
E06 Thyroiditis	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283
E03.8 Other specified hypothyroidism	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.717	0.283
Z95.8 Presence of other cardiac and vascular implants and grafts	0.717	0.283
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.716	0.284
I20-I25 Ischaemic heart diseases	0.716	0.284
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.713	0.287
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.712	0.288
I31 Other diseases of pericardium	0.712	0.288
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.712	0.288
T15-T19 Effects of foreign body entering through natural orifice	0.711	0.288
G90-G99 Other disorders of the nervous system	0.711	0.288
H46-H48 Disorders of optic nerve and visual pathways	0.711	0.289
H10-H13 Disorders of conjunctiva	0.711	0.289
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.710	0.290
Z91.5 Personal history of self-harm	0.710	0.290
D31 Benign neoplasm of eye and adnexa	0.709	0.291
D30 Benign neoplasm of urinary organs	0.709	0.291
D29 Benign neoplasm of male genital organs	0.709	0.291
D28 Benign neoplasm of other and unspecified female genital organs	0.709	0.291
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.709	0.291
D19 Benign neoplasm of mesothelial tissue	0.709	0.291
D16 Benign neoplasm of bone and articular cartilage	0.709	0.291
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.709	0.291
G70-G73 Diseases of myoneural junction and muscle	0.709	0.291
G00-G09 Inflammatory diseases of the central nervous system	0.709	0.291
D12.9 Anus and anal canal	0.709	0.291
D12.1 Appendix	0.709	0.291
E65-E68 Obesity and other hyperalimentation	0.709	0.291
S60.8 Other superficial injuries of wrist and hand	0.708	0.292
S62 Fracture at wrist and hand level	0.707	0.293
H26.4 After-cataract	0.707	0.293
H32 Chorioretinal disorders in diseases classified elsewhere	0.706	0.294
H31 Other disorders of choroid	0.706	0.294
H30 Chorioretinal inflammation	0.706	0.294
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.706	0.294
A04.5 Campylobacter enteritis	0.705	0.295
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.704	0.296
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.703	0.297
D17 Benign lipomatous neoplasm	0.701	0.299
D27 Benign neoplasm of ovary	0.701	0.299
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.699	0.301
Z83 Family history of other specific disorders	0.699	0.301
H33 Retinal detachments and breaks	0.699	0.301
H36.8 Other retinal disorders in diseases classified elsewhere	0.698	0.302
S42.3 Fracture of shaft of humerus	0.697	0.303
S70-S79 Injuries to the hip and thigh	0.697	0.303
S90-S99 Injuries to the ankle and foot	0.696	0.304
B99-B99 Other infectious diseases	0.696	0.304
B90-B94 Sequelae of infectious and parasitic diseases	0.696	0.304
B85-B89 Pediculosis, acariasis and other infestations	0.696	0.304
B65-B83 Helminthiases	0.696	0.304
B50-B64 Protozoal diseases	0.696	0.304
B20-B24 Human immunodeficiency virus [HIV] disease	0.696	0.304
B15-B19 Viral hepatitis	0.696	0.304
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.696	0.304
A80-A89 Viral infections of the central nervous system	0.696	0.304
A75-A79 Rickettsioses	0.696	0.304
A70-A74 Other diseases caused by chlamydiae	0.696	0.304
A65-A69 Other spirochaetal diseases	0.696	0.304
A50-A64 Infections with a predominantly sexual mode of transmission	0.696	0.304
A20-A28 Certain zoonotic bacterial diseases	0.696	0.304
A15-A19 Tuberculosis	0.696	0.304
C44.9 Malignant neoplasm of skin, unspecified	0.696	0.304
C44.8 Overlapping lesion of skin	0.696	0.304
S68 Traumatic amputation of wrist and hand	0.695	0.304
G37 Other demyelinating diseases of central nervous system	0.695	0.305
G36 Other acute disseminated demyelination	0.695	0.305
C18 Malignant neoplasm of colon	0.695	0.305
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.694	0.306
C25 Malignant neoplasm of pancreas	0.692	0.308
S49 Other and unspecified injuries of shoulder and upper arm	0.692	0.308
S48 Traumatic amputation of shoulder and upper arm	0.692	0.308
S46 Injury of muscle and tendon at shoulder and upper arm level	0.692	0.308
S45 Injury of blood vessels at shoulder and upper arm level	0.692	0.308
S44 Injury of nerves at shoulder and upper arm level	0.692	0.308
S41 Open wound of shoulder and upper arm	0.692	0.308
S40 Superficial injury of shoulder and upper arm	0.692	0.308
S47 Crushing injury of shoulder and upper arm	0.692	0.308
I50 Heart failure	0.691	0.309
S42.10 Fracture of scapula (closed)	0.690	0.310
T88.7 Unspecified adverse effect of drug or medicament	0.689	0.311
S42.4 Fracture of lower end of humerus	0.688	0.312
D33 Benign neoplasm of brain and other parts of central nervous system	0.687	0.312
C50.6 Axillary tail of breast	0.687	0.313
C50.5 Lower-outer quadrant of breast	0.687	0.313
C50.0 Nipple and areola	0.687	0.313
A08.4 Viral intestinal infection, unspecified	0.685	0.315
G58 Other mononeuropathies	0.684	0.316
Z95.0 Presence of cardiac pacemaker	0.683	0.316
C15.9 Oesophagus, unspecified	0.683	0.317
H53-H54 Visual disturbances and blindness	0.682	0.318
K62.7 Radiation proctitis	0.680	0.319
C67 Malignant neoplasm of bladder	0.680	0.320
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.680	0.320
E11 Non-insulin-dependent diabetes mellitus	0.680	0.320
S64 Injury of nerves at wrist and hand level	0.679	0.321
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.679	0.321
D34 Benign neoplasm of thyroid gland	0.679	0.321
F60-F69 Disorders of adult personality and behaviour	0.679	0.321
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.679	0.321
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.678	0.322
W00-W19 Falls	0.678	0.322
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.677	0.323
Z04 Examination and observation for other reasons	0.676	0.324
H25 Senile cataract	0.674	0.326
C19 Malignant neoplasm of rectosigmoid junction	0.674	0.326
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.674	0.326
S50 Superficial injury of forearm	0.674	0.326
K70.4 Alcoholic hepatic failure	0.674	0.326
H35.3 Degeneration of macula and posterior pole	0.674	0.326
I49 Other cardiac arrhythmias	0.673	0.327
S42.9 Fracture of shoulder girdle, part unspecified	0.673	0.327
S42.8 Fracture of other parts of shoulder and upper arm	0.673	0.327
S42.7 Multiple fractures of clavicle, scapula and humerus	0.673	0.327
Z90.2 Acquired absence of lung [part of]	0.672	0.328
F99-F99 Unspecified mental disorder	0.672	0.328
K76 Other diseases of liver	0.668	0.332
T43.3 Phenothiazine antipsychotics and neuroleptics	0.668	0.332
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.666	0.334
Z94 Transplanted organ and tissue status	0.665	0.335
K55.2 Angiodysplasia of colon	0.665	0.335
S20 Superficial injury of thorax	0.664	0.336
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.664	0.336
B35 Dermatophytosis	0.663	0.336
K75 Other inflammatory liver diseases	0.663	0.337
E50-E64 Other nutritional deficiencies	0.663	0.337
Z89 Acquired absence of limb	0.662	0.338
Z84 Family history of other conditions	0.662	0.338
Z81 Family history of mental and behavioural disorders	0.662	0.338
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.662	0.338
S69 Other and unspecified injuries of wrist and hand	0.662	0.338
S67 Crushing injury of wrist and hand	0.662	0.338
S65 Injury of blood vessels at wrist and hand level	0.662	0.338
H65-H75 Diseases of middle ear and mastoid	0.661	0.339
I50.1 Left ventricular failure	0.660	0.340
A49 Bacterial infection of unspecified site	0.660	0.340
F00-F09 Organic, including symptomatic, mental disorders	0.660	0.340
A07 Other protozoal intestinal diseases	0.659	0.341
A06 Amoebiasis	0.659	0.341
A05 Other bacterial foodborne intoxications	0.659	0.341
A03 Shigellosis	0.659	0.341
A02 Other Salmonella infections	0.659	0.341
A01 Typhoid and paratyphoid fevers	0.659	0.341
A00 Cholera	0.659	0.341
K64 Haemorrhoids and perianal venous thrombosis	0.658	0.342
S82 Fracture of lower leg, including ankle	0.657	0.343
C50.8 Overlapping lesion of breast	0.657	0.343
K62.0 Anal polyp	0.657	0.343
Chapter XIV Diseases of the genitourinary system	0.657	0.343
I46 Cardiac arrest	0.656	0.344
K62.6 Ulcer of anus and rectum	0.656	0.344
K62.4 Stenosis of anus and rectum	0.656	0.344
K62.2 Anal prolapse	0.656	0.344
T87 Complications peculiar to reattachment and amputation	0.655	0.344
T86 Failure and rejection of transplanted organs and tissues	0.655	0.344
T80 Complications following infusion, transfusion and therapeutic injection	0.655	0.344
C26 Malignant neoplasm of other and ill-defined digestive organs	0.655	0.345
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.655	0.345
C21 Malignant neoplasm of anus and anal canal	0.655	0.345
C17 Malignant neoplasm of small intestine	0.655	0.345
C16 Malignant neoplasm of stomach	0.655	0.345
C23 Malignant neoplasm of gallbladder	0.655	0.345
T81.8 Other complications of procedures, not elsewhere classified	0.654	0.346
C43.7 Malignant melanoma of lower limb, including hip	0.654	0.346
I31.3 Pericardial effusion (noninflammatory)	0.653	0.347
Z90.7 Acquired absence of genital organ(s)	0.652	0.348
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.652	0.348
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.652	0.348
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.652	0.348
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.652	0.348
Z82.2 Family history of deafness and hearing loss	0.652	0.348
Z82.1 Family history of blindness and visual loss	0.652	0.348
D46 Myelodysplastic syndromes	0.652	0.348
Z85.0 Personal history of malignant neoplasm of digestive organs	0.652	0.348
Z85.9 Personal history of malignant neoplasm, unspecified	0.652	0.348
K74 Fibrosis and cirrhosis of liver	0.652	0.348
T83.0 Mechanical complication of urinary (indwelling) catheter	0.651	0.348
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.651	0.349
S06 Intracranial injury	0.650	0.350
D36.7 Other specified sites	0.650	0.350
Z85.6 Personal history of leukaemia	0.650	0.350
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.648	0.351
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.648	0.351
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.648	0.351
T46 Poisoning by agents primarily affecting the cardiovascular system	0.648	0.351
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.648	0.351
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.648	0.351
T41 Poisoning by anaesthetics and therapeutic gases	0.648	0.351
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.648	0.351
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.648	0.351
T36 Poisoning by systemic antibiotics	0.648	0.351
Z70-Z76 Persons encountering health services in other circumstances	0.648	0.352
G59 Mononeuropathy in diseases classified elsewhere	0.646	0.353
G54 Nerve root and plexus disorders	0.645	0.355
G53 Cranial nerve disorders in diseases classified elsewhere	0.645	0.355
G52 Disorders of other cranial nerves	0.645	0.355
G50 Disorders of trigeminal nerve	0.645	0.355
D11 Benign neoplasm of major salivary glands	0.645	0.355
H34.8 Other retinal vascular occlusions	0.645	0.355
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.643	0.357
E14.3 With ophthalmic complications	0.643	0.357
D60-D64 Aplastic and other anaemias	0.643	0.357
T43.2 Other and unspecified antidepressants	0.642	0.357
S00 Superficial injury of head	0.642	0.358
B25-B34 Other viral diseases	0.642	0.358
Z97 Presence of other devices	0.642	0.358
D35 Benign neoplasm of other and unspecified endocrine glands	0.642	0.358
Z90.0 Acquired absence of part of head and neck	0.641	0.359
B00 Herpesviral [herpes simplex] infections	0.640	0.360
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.640	0.360
S52.6 Fracture of lower end of both ulna and radius	0.640	0.360
C43.5 Malignant melanoma of trunk	0.640	0.360
C44.6 Skin of upper limb, including shoulder	0.639	0.361
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.638	0.362
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.638	0.362
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.638	0.362
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.638	0.362
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.638	0.362
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.638	0.362
E15 Nondiabetic hypoglycaemic coma	0.637	0.363
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.637	0.363
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.636	0.364
F80-F89 Disorders of psychological development	0.636	0.364
F70-F79 Mental retardation	0.636	0.364
Z98 Other postsurgical states	0.636	0.364
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.635	0.365
H90-H95 Other disorders of ear	0.634	0.366
S60.9 Superficial injury of wrist and hand, unspecified	0.633	0.366
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.633	0.367
A04.9 Bacterial intestinal infection, unspecified	0.632	0.368
A04.6 Enteritis due to Yersinia enterocolitica	0.632	0.368
A04.4 Other intestinal Escherichia coli infections	0.632	0.368
A04.3 Enterohaemorrhagic Escherichia coli infection	0.632	0.368
A04.2 Enteroinvasive Escherichia coli infection	0.632	0.368
A04.1 Enterotoxigenic Escherichia coli infection	0.632	0.368
A04.0 Enteropathogenic Escherichia coli infection	0.632	0.368
S22 Fracture of rib(s), sternum and thoracic spine	0.632	0.368
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.631	0.369
H27 Other disorders of lens	0.631	0.369
C22.1 Intrahepatic bile duct carcinoma	0.628	0.372
E07.9 Disorder of thyroid, unspecified	0.627	0.373
I70-I79 Diseases of arteries, arterioles and capillaries	0.627	0.373
T93 Sequelae of injuries of lower limb	0.627	0.373
C79 Secondary malignant neoplasm of other sites	0.626	0.374
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.626	0.374
D36.1 Peripheral nerves and autonomic nervous system	0.625	0.375
K93 Disorders of other digestive organs in diseases classified elsewhere	0.624	0.375
I95-I99 Other and unspecified disorders of the circulatory system	0.624	0.376
S59 Other and unspecified injuries of forearm	0.622	0.378
S58 Traumatic amputation of forearm	0.622	0.378
S57 Crushing injury of forearm	0.622	0.378
S56 Injury of muscle and tendon at forearm level	0.622	0.378
S55 Injury of blood vessels at forearm level	0.622	0.378
S54 Injury of nerves at forearm level	0.622	0.378
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.622	0.378
S51 Open wound of forearm	0.622	0.378
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.622	0.378
E05.0 Thyrotoxicosis with diffuse goitre	0.621	0.379
C15.5 Lower third of oesophagus	0.621	0.379
X20-X29 Contact with venomous animals and plants	0.620	0.380
G20-G26 Extrapyramidal and movement disorders	0.620	0.380
C64 Malignant neoplasm of kidney, except renal pelvis	0.619	0.381
E14.8 With unspecified complications	0.619	0.381
E14.7 With multiple complications	0.619	0.381
E14.6 With other specified complications	0.619	0.381
E14.5 With peripheral circulatory complications	0.619	0.381
E14.4 With neurological complications	0.619	0.381
E14.2 Withrenal complications	0.619	0.381
E14.1 With ketoacidosis	0.619	0.381
E14.0 With coma	0.619	0.381
D26.1 Corpus uteri	0.618	0.382
S52.5 Fracture of lower end of radius	0.617	0.383
C68 Malignant neoplasm of other and unspecified urinary organs	0.617	0.383
C65 Malignant neoplasm of renal pelvis	0.617	0.383
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.617	0.383
D38.1 Trachea, bronchus and lung	0.616	0.384
H43 Disorders of vitreous body	0.615	0.385
T85 Complications of other internal prosthetic devices, implants and grafts	0.615	0.385
K77 Liver disorders in diseases classified elsewhere	0.614	0.386
K73 Chronic hepatitis, not elsewhere classified	0.614	0.386
K72 Hepatic failure, not elsewhere classified	0.614	0.386
K71 Toxic liver disease	0.614	0.386
K63.8 Other specified diseases of intestine	0.614	0.386
C43.9 Malignant melanoma of skin, unspecified	0.612	0.387
C43.8 Overlapping malignant melanoma of skin	0.612	0.387
C43.3 Malignant melanoma of other and unspecified parts of face	0.612	0.387
C43.2 Malignant melanoma of ear and external auricular canal	0.612	0.387
C43.1 Malignant melanoma of eyelid, including canthus	0.612	0.387
C43.0 Malignant melanoma of lip	0.612	0.387
B95-B98 Bacterial, viral and other infectious agents	0.612	0.388
E05.9 Thyrotoxicosis, unspecified	0.611	0.388
Z96 Presence of other functional implants	0.610	0.389
E11.3 With ophthalmic complications	0.610	0.390
G82 Paraplegia and tetraplegia	0.610	0.390
Z90.8 Acquired absence of other organs	0.609	0.390
C44.2 Skin of ear and external auricular canal	0.609	0.391
T78.4 Allergy, unspecified	0.609	0.391
T43.0 Tricyclic and tetracyclic antidepressants	0.608	0.392
S02 Fracture of skull and facial bones	0.607	0.393
K90.9 Intestinal malabsorption, unspecified	0.607	0.393
K90.8 Other intestinal malabsorption	0.607	0.393
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.607	0.393
K90.3 Pancreatic steatorrhoea	0.607	0.393

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations