TreeWAS – Variant ID: rs2479808

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.059	0.941
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.054	0.946
Chapter XI Diseases of the digestive system	0.053	0.947
Chapter VI Diseases of the nervous system	0.052	0.948
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.050	0.950
Chapter XX External causes of morbidity and mortality	0.048	0.951
Chapter IV Endocrine, nutritional and metabolic diseases	0.047	0.952
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.047	0.953
Chapter XXI Factors influencing health status and contact with health services	0.047	0.953
G50-G59 Nerve, nerve root and plexus disorders	0.046	0.954
M15-M19 Arthrosis	0.046	0.954
Chapter IX Diseases of the circulatory system	0.046	0.954
Chapter VII Diseases of the eye and adnexa	0.044	0.956
Chapter V Mental and behavioural disorders	0.044	0.956
K55-K64 Other diseases of intestines	0.044	0.956
Chapter I Certain infectious and parasitic diseases	0.043	0.957
M05-M14 Inflammatory polyarthropathies	0.043	0.957
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.043	0.957
Chapter XXII Codes for special purposes	0.042	0.957
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.042	0.957
Chapter XVI Certain conditions originating in the perinatal period	0.042	0.957
Chapter XV Pregnancy, childbirth and the puerperium	0.042	0.957
Chapter VIII Diseases of the ear and mastoid process	0.042	0.957
K20-K31 Diseases of oesophagus, stomach and duodenum	0.042	0.958
Chapter XII Diseases of the skin and subcutaneous tissue	0.042	0.958
M45-M49 Spondylopathies	0.041	0.958
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.041	0.958
M50-M54 Other dorsopathies	0.041	0.959
M70-M79 Other soft tissue disorders	0.041	0.959
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.041	0.959
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.041	0.959
K50-K52 Noninfective enteritis and colitis	0.041	0.959
Chapter II Neoplasms	0.041	0.959
G56 Mononeuropathies of upper limb	0.041	0.959
K90-K93 Other diseases of the digestive system	0.040	0.960
Chapter X Diseases of the respiratory system	0.040	0.960
Chapter XIV Diseases of the genitourinary system	0.040	0.960
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.039	0.961
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.039	0.961
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.039	0.961
M91-M94 Chondropathies	0.039	0.961
M86-M90 Other osteopathies	0.039	0.961
M80-M85 Disorders of bone density and structure	0.039	0.961
M65-M68 Disorders of synovium and tendon	0.039	0.961
M60-M63 Disorders of muscles	0.039	0.961
M40-M43 Deforming dorsopathies	0.039	0.961
M00-M03 Infectious arthropathies	0.039	0.961
G40-G47 Episodic and paroxysmal disorders	0.039	0.961
M20-M25 Other joint disorders	0.038	0.961
K70-K77 Diseases of liver	0.038	0.962
K65-K67 Diseases of peritoneum	0.038	0.962
K35-K38 Diseases of appendix	0.038	0.962
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.038	0.962
K40-K46 Hernia	0.038	0.962
M17 Gonarthrosis [arthrosis of knee]	0.038	0.962
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.037	0.963
G90-G99 Other disorders of the nervous system	0.037	0.963
G80-G83 Cerebral palsy and other paralytic syndromes	0.037	0.963
G70-G73 Diseases of myoneural junction and muscle	0.037	0.963
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.037	0.963
G35-G37 Demyelinating diseases of the central nervous system	0.037	0.963
G30-G32 Other degenerative diseases of the nervous system	0.037	0.963
G20-G26 Extrapyramidal and movement disorders	0.037	0.963
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.037	0.963
G00-G09 Inflammatory diseases of the central nervous system	0.037	0.963
K63 Other diseases of intestine	0.037	0.963
G56.0 Carpal tunnel syndrome	0.037	0.963
E70-E90 Metabolic disorders	0.036	0.963
M16 Coxarthrosis [arthrosis of hip]	0.036	0.963
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.036	0.964
E00-E07 Disorders of thyroid gland	0.036	0.964
R07 Pain in throat and chest	0.036	0.964
R50-R69 General symptoms and signs	0.036	0.964
Z70-Z76 Persons encountering health services in other circumstances	0.036	0.964
I20-I25 Ischaemic heart diseases	0.036	0.964
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.036	0.964
R95-R99 Ill-defined and unknown causes of mortality	0.036	0.964
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.036	0.964
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.036	0.964
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.036	0.964
R47-R49 Symptoms and signs involving speech and voice	0.036	0.964
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.036	0.964
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.036	0.964
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.036	0.964
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.036	0.964
M13 Other arthritis	0.036	0.964
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.036	0.964
E65-E68 Obesity and other hyperalimentation	0.035	0.965
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.035	0.965
R30-R39 Symptoms and signs involving the urinary system	0.035	0.965
R05 Cough	0.035	0.965
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.035	0.965
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.035	0.965
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.035	0.965
Y60-Y69 Misadventures to patients during surgical and medical care	0.035	0.965
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.035	0.965
Y35-Y36 Legal intervention and operations of war	0.035	0.965
Y10-Y34 Event of undetermined intent	0.035	0.965
Y00-Y09 Assault	0.035	0.965
X85-X99 Assault	0.035	0.965
X60-X84 Intentional self-harm	0.035	0.965
X58-X59 Accidental exposure to other and unspecified factors	0.035	0.965
X50-X57 Overexertion, travel and privation	0.035	0.965
X40-X49 Accidental poisoning by and exposure to noxious substances	0.035	0.965
X30-X39 Exposure to forces of nature	0.035	0.965
X20-X29 Contact with venomous animals and plants	0.035	0.965
X10-X19 Contact with heat and hot substances	0.035	0.965
X00-X09 Exposure to smoke, fire and flames	0.035	0.965
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.035	0.965
W75-W84 Other accidental threats to breathing	0.035	0.965
W65-W74 Accidental drowning and submersion	0.035	0.965
W50-W64 Exposure to animate mechanical forces	0.035	0.965
W20-W49 Exposure to inanimate mechanical forces	0.035	0.965
W00-W19 Falls	0.035	0.965
V98-V99 Other and unspecified transport accidents	0.035	0.965
V95-V97 Air and space transport accidents	0.035	0.965
V90-V94 Water transport accidents	0.035	0.965
V80-V89 Other land transport accidents	0.035	0.965
V70-V79 Bus occupant injured in transport accident	0.035	0.965
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.035	0.965
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.035	0.965
V40-V49 Car occupant injured in transport accident	0.035	0.965
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.035	0.965
V20-V29 Motorcycle rider injured in transport accident	0.035	0.965
V10-V19 Pedal cyclist injured in transport accident	0.035	0.965
V01-V09 Pedestrian injured in transport accident	0.035	0.965
E10-E14 Diabetes mellitus	0.035	0.965
K59 Other functional intestinal disorders	0.034	0.966
E50-E64 Other nutritional deficiencies	0.034	0.966
E40-E46 Malnutrition	0.034	0.966
E20-E35 Disorders of other endocrine glands	0.034	0.966
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.034	0.966
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.034	0.966
T79-T79 Certain early complications of trauma	0.034	0.966
T66-T78 Other and unspecified effects of external causes	0.034	0.966
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.034	0.966
T36-T50 Poisoning by drugs, medicaments and biological substances	0.034	0.966
T33-T35 Frostbite	0.034	0.966
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.034	0.966
T26-T28 Burns and corrosions confined to eye and internal organs	0.034	0.966
T20-T25 Burns and corrosions of external body surface, specified by site	0.034	0.966
T15-T19 Effects of foreign body entering through natural orifice	0.034	0.966
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.034	0.966
T00-T07 Injuries involving multiple body regions	0.034	0.966
S90-S99 Injuries to the ankle and foot	0.034	0.966
S80-S89 Injuries to the knee and lower leg	0.034	0.966
S70-S79 Injuries to the hip and thigh	0.034	0.966
S60-S69 Injuries to the wrist and hand	0.034	0.966
S50-S59 Injuries to the elbow and forearm	0.034	0.966
S40-S49 Injuries to the shoulder and upper arm	0.034	0.966
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.034	0.966
S20-S29 Injuries to the thorax	0.034	0.966
S10-S19 Injuries to the neck	0.034	0.966
S00-S09 Injuries to the head	0.034	0.966
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.034	0.966
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.034	0.966
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.034	0.966
I10-I15 Hypertensive diseases	0.034	0.966
K29 Gastritis and duodenitis	0.034	0.966
Z00-Z13 Persons encountering health services for examination and investigation	0.033	0.966
Z96 Presence of other functional implants	0.033	0.967
G59 Mononeuropathy in diseases classified elsewhere	0.033	0.967
G58 Other mononeuropathies	0.033	0.967
G57 Mononeuropathies of lower limb	0.033	0.967
G54 Nerve root and plexus disorders	0.033	0.967
G53 Cranial nerve disorders in diseases classified elsewhere	0.033	0.967
G52 Disorders of other cranial nerves	0.033	0.967
G51 Facial nerve disorders	0.033	0.967
G50 Disorders of trigeminal nerve	0.033	0.967
M19 Other arthrosis	0.033	0.967
M18 Arthrosis of first carpometacarpal joint	0.033	0.967
M15 Polyarthrosis	0.033	0.967
I95-I99 Other and unspecified disorders of the circulatory system	0.033	0.967
I70-I79 Diseases of arteries, arterioles and capillaries	0.033	0.967
I60-I69 Cerebrovascular diseases	0.033	0.967
I30-I52 Other forms of heart disease	0.033	0.967
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.033	0.967
I05-I09 Chronic rheumatic heart diseases	0.033	0.967
I00-I02 Acute rheumatic fever	0.033	0.967
K80 Cholelithiasis	0.032	0.967
A00-A09 Intestinal infectious diseases	0.032	0.967
M47 Spondylosis	0.032	0.967
M51 Other intervertebral disk disorders	0.032	0.968
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.032	0.968
K52 Other non-infective gastro-enteritis and colitis	0.032	0.968
M75 Shoulder lesions	0.032	0.968
K58 Irritable bowel syndrome	0.032	0.968
Y83.1 Surgical operation with implant of artificial internal device	0.032	0.968
R19 Other symptoms and signs involving the digestive system and abdomen	0.032	0.968
Z88.0 Personal history of allergy to penicillin	0.032	0.968
H55-H59 Other disorders of eye and adnexa	0.032	0.968
H53-H54 Visual disturbances and blindness	0.032	0.968
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.032	0.968
H46-H48 Disorders of optic nerve and visual pathways	0.032	0.968
H43-H45 Disorders of vitreous body and globe	0.032	0.968
H40-H42 Glaucoma	0.032	0.968
H30-H36 Disorders of choroid and retina	0.032	0.968
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.032	0.968
H10-H13 Disorders of conjunctiva	0.032	0.968
F99-F99 Unspecified mental disorder	0.032	0.968
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.032	0.968
F80-F89 Disorders of psychological development	0.032	0.968
F70-F79 Mental retardation	0.032	0.968
F60-F69 Disorders of adult personality and behaviour	0.032	0.968
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.032	0.968
F40-F48 Neurotic, stress-related and somatoform disorders	0.032	0.968
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.032	0.968
F00-F09 Organic, including symptomatic, mental disorders	0.032	0.968
M17.1 Other primary gonarthrosis	0.031	0.968
K64 Haemorrhoids and perianal venous thrombosis	0.031	0.968
K61 Abscess of anal and rectal regions	0.031	0.968
K60 Fissure and fistula of anal and rectal regions	0.031	0.968
K56 Paralytic ileus and intestinal obstruction without hernia	0.031	0.968
K55 Vascular disorders of intestine	0.031	0.968
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.031	0.968
M16.1 Other primary coxarthrosis	0.031	0.968
K22 Other diseases of oesophagus	0.031	0.968
K21 Gastro-oesophageal reflux disease	0.031	0.969
B99-B99 Other infectious diseases	0.031	0.969
B90-B94 Sequelae of infectious and parasitic diseases	0.031	0.969
B85-B89 Pediculosis, acariasis and other infestations	0.031	0.969
B65-B83 Helminthiases	0.031	0.969
B50-B64 Protozoal diseases	0.031	0.969
B35-B49 Mycoses	0.031	0.969
B25-B34 Other viral diseases	0.031	0.969
B20-B24 Human immunodeficiency virus [HIV] disease	0.031	0.969
B15-B19 Viral hepatitis	0.031	0.969
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.031	0.969
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.031	0.969
A80-A89 Viral infections of the central nervous system	0.031	0.969
A75-A79 Rickettsioses	0.031	0.969
A70-A74 Other diseases caused by chlamydiae	0.031	0.969
A65-A69 Other spirochaetal diseases	0.031	0.969
A50-A64 Infections with a predominantly sexual mode of transmission	0.031	0.969
A30-A49 Other bacterial diseases	0.031	0.969
A20-A28 Certain zoonotic bacterial diseases	0.031	0.969
A15-A19 Tuberculosis	0.031	0.969
M14 Arthropathies in other diseases classified elsewhere	0.031	0.969
M12 Other specific arthropathies	0.031	0.969
M11 Other crystal arthropathies	0.031	0.969
M10 Gout	0.031	0.969
M09 Juvenile arthritis in diseases classified elsewhere	0.031	0.969
M08 Juvenile arthritis	0.031	0.969
M07 Psoriatic and enteropathic arthropathies	0.031	0.969
M06 Other rheumatoid arthritis	0.031	0.969
M05 Seropositive rheumatoid arthritis	0.031	0.969
B95-B98 Bacterial, viral and other infectious agents	0.031	0.969
K92 Other diseases of digestive system	0.031	0.969
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.031	0.969
R04 Haemorrhage from respiratory passages	0.031	0.969
R03 Abnormal blood-pressure reading, without diagnosis	0.031	0.969
R01 Cardiac murmurs and other cardiac sounds	0.031	0.969
R00 Abnormalities of heart beat	0.031	0.969
R02 Gangrene, not elsewhere classified	0.031	0.969
K63.8 Other specified diseases of intestine	0.031	0.969
K30 Dyspepsia	0.031	0.969
F30-F39 Mood [affective] disorders	0.031	0.969
H90-H95 Other disorders of ear	0.031	0.969
H80-H83 Diseases of inner ear	0.031	0.969
H65-H75 Diseases of middle ear and mastoid	0.031	0.969
H60-H62 Diseases of external ear	0.031	0.969
O94-O99 Other obstetric conditions, not elsewhere classified	0.031	0.969
O85-O92 Complications predominantly related to the puerperium	0.031	0.969
O80-O84 Delivery	0.031	0.969
O60-O75 Complications of labour and delivery	0.031	0.969
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.031	0.969
O20-O29 Other maternal disorders predominantly related to pregnancy	0.031	0.969
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.031	0.969
O00-O08 Pregnancy with abortive outcome	0.031	0.969
P90-P96 Other disorders originating in the perinatal period	0.031	0.969
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.031	0.969
P75-P78 Digestive system disorders of fetus and newborn	0.031	0.969
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.031	0.969
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.031	0.969
P35-P39 Infections specific to the perinatal period	0.031	0.969
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.031	0.969
P10-P15 Birth trauma	0.031	0.969
P05-P08 Disorders related to length of gestation and fetal growth	0.031	0.969
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.031	0.969
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.031	0.969
Q80-Q89 Other congenital malformations	0.031	0.969
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.031	0.969
Q60-Q64 Congenital malformations of the urinary system	0.031	0.969
Q50-Q56 Congenital malformations of genital organs	0.031	0.969
Q38-Q45 Other congenital malformations of the digestive system	0.031	0.969
Q35-Q37 Cleft lip and cleft palate	0.031	0.969
Q30-Q34 Congenital malformations of the respiratory system	0.031	0.969
Q20-Q28 Congenital malformations of the circulatory system	0.031	0.969
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.031	0.969
Q00-Q07 Congenital malformations of the nervous system	0.031	0.969
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.031	0.969
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.031	0.969
R06 Abnormalities of breathing	0.031	0.969
K62 Other diseases of anus and rectum	0.031	0.969
H25-H28 Disorders of lens	0.030	0.969
N30-N39 Other diseases of urinary system	0.030	0.969
Z60 Problems related to social environment	0.030	0.969
C43-C44 Melanoma and other malignant neoplasms of skin	0.030	0.969
K31 Other diseases of stomach and duodenum	0.030	0.970
K28 Gastrojejunal ulcer	0.030	0.970
K27 Peptic ulcer, site unspecified	0.030	0.970
K26 Duodenal ulcer	0.030	0.970
K25 Gastric ulcer	0.030	0.970
K23 Disorders of oesophagus in diseases classified elsewhere	0.030	0.970
M13.9 Arthritis, unspecified	0.030	0.970
L80-L99 Other disorders of the skin and subcutaneous tissue	0.030	0.970
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.030	0.970
L50-L54 Urticaria and erythema	0.030	0.970
L40-L45 Papulosquamous disorders	0.030	0.970
L20-L30 Dermatitis and eczema	0.030	0.970
L10-L14 Bullous disorders	0.030	0.970
M49 Spondylopathies in diseases classified elsewhere	0.030	0.970
M48 Other spondylopathies	0.030	0.970
M46 Other inflammatory spondylopathies	0.030	0.970
M45 Ankylosing spondylitis	0.030	0.970
L60-L75 Disorders of skin appendages	0.030	0.970
D80-D89 Certain disorders involving the immune mechanism	0.030	0.970
D70-D77 Other diseases of blood and blood-forming organs	0.030	0.970
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.030	0.970
D55-D59 Haemolytic anaemias	0.030	0.970
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.030	0.970
M54 Dorsalgia	0.030	0.970
M53 Other dorsopathies, not elsewhere classified	0.030	0.970
M50 Cervical disk disorders	0.030	0.970
M79 Other soft tissue disorders, not elsewhere classified	0.030	0.970
M77 Other enthesopathies	0.030	0.970
M76 Enthesopathies of lower limb, excluding foot	0.030	0.970
M73 Soft tissue disorders in diseases classified elsewhere	0.030	0.970
M72 Fibroblastic disorders	0.030	0.970
M71 Other bursopathies	0.030	0.970
M70 Soft tissue disorders related to use, overuse and pressure	0.030	0.970
D50-D53 Nutritional anaemias	0.030	0.970
K63.5 Polyp of colon	0.030	0.970
C60-C63 Malignant neoplasms of male genital organs	0.030	0.970
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.030	0.970
K86 Other diseases of pancreas	0.030	0.970
K85 Acute pancreatitis	0.030	0.970
K83 Other diseases of biliary tract	0.030	0.970
K82 Other diseases of gallbladder	0.030	0.970
K81 Cholecystitis	0.030	0.970
T81 Complications of procedures, not elsewhere classified	0.030	0.970
Z91 Personal history of risk-factors, not elsewhere classified	0.030	0.970
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.030	0.970
J30-J39 Other diseases of upper respiratory tract	0.030	0.970
R07.2 Precordial pain	0.030	0.970
K51 Ulcerative colitis	0.029	0.970
K50 Crohn's disease [regional enteritis]	0.029	0.970
D37-D48 Neoplasms of uncertain or unknown behaviour	0.029	0.970
D00-D09 In situ neoplasms	0.029	0.970
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.029	0.970
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.029	0.970
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.029	0.970
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.029	0.970
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.029	0.970
C64-C68 Malignant neoplasms of urinary tract	0.029	0.970
C51-C58 Malignant neoplasms of female genital organs	0.029	0.970
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.029	0.970
C40-C41 Malignant neoplasms of bone and articular cartilage	0.029	0.970
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.029	0.970
C15-C26 Malignant neoplasms of digestive organs	0.029	0.970
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.029	0.970
R07.3 Other chest pain	0.030	0.970
G40 Epilepsy	0.029	0.970
Z40-Z54 Persons encountering health services for specific procedures and health care	0.029	0.970
L00-L08 Infections of the skin and subcutaneous tissue	0.029	0.970
Z96.6 Presence of orthopaedic joint implants	0.029	0.970
G56.9 Mononeuropathy of upper limb, unspecified	0.029	0.970
G56.8 Other mononeuropathies of upper limb	0.029	0.970
G56.4 Causalgia	0.029	0.970
G56.3 Lesion of radial nerve	0.029	0.970
G56.2 Lesion of ulnar nerve	0.029	0.970
G56.1 Other lesions of median nerve	0.029	0.970
C50-C50 Malignant neoplasm of breast	0.029	0.971
Z95 Presence of cardiac and vascular implants and grafts	0.029	0.971
K93 Disorders of other digestive organs in diseases classified elsewhere	0.029	0.971
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.029	0.971
K90 Intestinal malabsorption	0.029	0.971
J95-J99 Other diseases of the respiratory system	0.029	0.971
J90-J94 Other diseases of pleura	0.029	0.971
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.029	0.971
J80-J84 Other respiratory diseases principally affecting the interstitium	0.029	0.971
J60-J70 Lung diseases due to external agents	0.029	0.971
J09-J18 Influenza and pneumonia	0.029	0.971
J00-J06 Acute upper respiratory infections	0.029	0.971
Z92 Personal history of medical treatment	0.029	0.971
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.029	0.971
D60-D64 Aplastic and other anaemias	0.029	0.971
N99-N99 Other disorders of the genitourinary system	0.029	0.971
N70-N77 Inflammatory diseases of female pelvic organs	0.029	0.971
N60-N64 Disorders of breast	0.029	0.971
N25-N29 Other disorders of kidney and ureter	0.029	0.971
N20-N23 Urolithiasis	0.029	0.971
N17-N19 Renal failure	0.029	0.971
N10-N16 Renal tubulo-interstitial diseases	0.029	0.971
N00-N08 Glomerular diseases	0.029	0.971
K43 Ventral hernia	0.029	0.971
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.029	0.971
R19.4 Change in bowel habit	0.029	0.971
I21 Acute myocardial infarction	0.029	0.971
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.028	0.971
Z85 Personal history of malignant neoplasm	0.028	0.971
Z72 Problems related to lifestyle	0.028	0.971
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.028	0.972
Z98 Other postsurgical states	0.028	0.972
Z97 Presence of other devices	0.028	0.972
Z94 Transplanted organ and tissue status	0.028	0.972
Z93 Artificial opening status	0.028	0.972
Z89 Acquired absence of limb	0.028	0.972
Z84 Family history of other conditions	0.028	0.972
Z83 Family history of other specific disorders	0.028	0.972
Z81 Family history of mental and behavioural disorders	0.028	0.972
N80-N98 Noninflammatory disorders of female genital tract	0.028	0.972
E03 Other hypothyroidism	0.028	0.972
G47 Sleep disorders	0.028	0.972
T88 Other complications of surgical and medical care, not elsewhere classified	0.028	0.972
T87 Complications peculiar to reattachment and amputation	0.028	0.972
T86 Failure and rejection of transplanted organs and tissues	0.028	0.972
T85 Complications of other internal prosthetic devices, implants and grafts	0.028	0.972
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.028	0.972
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.028	0.972
T80 Complications following infusion, transfusion and therapeutic injection	0.028	0.972
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.028	0.972
M02 Reactive arthropathies	0.028	0.972
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.028	0.972
M00 Pyogenic arthritis	0.028	0.972
M43 Other deforming dorsopathies	0.028	0.972
M42 Spinal osteochondrosis	0.028	0.972
M41 Scoliosis	0.028	0.972
M40 Kyphosis and lordosis	0.028	0.972
M63 Disorders of muscle in diseases classified elsewhere	0.028	0.972
M62 Other disorders of muscle	0.028	0.972
M61 Calcification and ossification of muscle	0.028	0.972
M60 Myositis	0.028	0.972
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.028	0.972
M67 Other disorders of synovium and tendon	0.028	0.972
M66 Spontaneous rupture of synovium and tendon	0.028	0.972
M65 Synovitis and tenosynovitis	0.028	0.972
M85 Other disorders of bone density and structure	0.028	0.972
M84 Disorders of continuity of bone	0.028	0.972
M83 Adult osteomalacia	0.028	0.972
M82 Osteoporosis in diseases classified elsewhere	0.028	0.972
M81 Osteoporosis without pathological fracture	0.028	0.972
M80 Osteoporosis with pathological fracture	0.028	0.972
M90 Osteopathies in diseases classified elsewhere	0.028	0.972
M89 Other disorders of bone	0.028	0.972
M88 Paget's disease of bone [osteitis deformans]	0.028	0.972
M87 Osteonecrosis	0.028	0.972
M86 Osteomyelitis	0.028	0.972
M94 Other disorders of cartilage	0.028	0.972
M93 Other osteochondropathies	0.028	0.972
M92 Other juvenile osteochondrosis	0.028	0.972
M91 Juvenile osteochondrosis of hip and pelvis	0.028	0.972
M99 Biomechanical lesions, not elsewhere classified	0.028	0.972
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.028	0.972
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.028	0.972
R32 Unspecified urinary incontinence	0.028	0.972
R33 Retention of urine	0.028	0.972
G46 Vascular syndromes of brain in cerebrovascular diseases	0.028	0.972
G45 Transient cerebral ischaemic attacks and related syndromes	0.028	0.972
G44 Other headache syndromes	0.028	0.972
G43 Migraine	0.028	0.972
G41 Status epilepticus	0.028	0.972
J20-J22 Other acute lower respiratory infections	0.028	0.972
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.028	0.972
M35 Other systemic involvement of connective tissue	0.028	0.972
M34 Systemic sclerosis	0.028	0.972
M33 Dermatopolymyositis	0.028	0.972
M32 Systemic lupus erythematosus	0.028	0.972
M31 Other necrotising vasculopathies	0.028	0.972
M30 Polyarteritis nodosa and related conditions	0.028	0.972
M25 Other joint disorders, not elsewhere classified	0.028	0.972
M24 Other specific joint derangements	0.028	0.972
M23 Internal derangement of knee	0.028	0.972
M22 Disorders of patella	0.028	0.972
M21 Other acquired deformities of limbs	0.028	0.972
K14 Diseases of tongue	0.028	0.972
K13 Other diseases of lip and oral mucosa	0.028	0.972
K12 Stomatitis and related lesions	0.028	0.972
K11 Diseases of salivary glands	0.028	0.972
K10 Other diseases of jaws	0.028	0.972
K09 Cysts of oral region, not elsewhere classified	0.028	0.972
K08 Other disorders of teeth and supporting structures	0.028	0.972
K07 Dentofacial anomalies [including malocclusion]	0.028	0.972
K06 Other disorders of gingiva and edentulous alveolar ridge	0.028	0.972
K05 Gingivitis and periodontal diseases	0.028	0.972
K04 Diseases of pulp and periapical tissues	0.028	0.972
K03 Other diseases of hard tissues of teeth	0.028	0.972
K02 Dental caries	0.028	0.972
K01 Embedded and impacted teeth	0.028	0.972
K00 Disorders of tooth development and eruption	0.028	0.972
K38 Other diseases of appendix	0.028	0.972
K35 Acute appendicitis	0.028	0.972
K37 Unspecified appendicitis	0.028	0.972
K36 Other appendicitis	0.028	0.972
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.028	0.972
K66 Other disorders of peritoneum	0.028	0.972
K65 Peritonitis	0.028	0.972
K77 Liver disorders in diseases classified elsewhere	0.028	0.972
K76 Other diseases of liver	0.028	0.972
K75 Other inflammatory liver diseases	0.028	0.972

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations