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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs28534493
log Bayes Factor = 20.6371
Chromosome 4   position 61,037,655  (GRCh37) Explore rs28534493 on Ensembl!
Variant rs28534493 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Z51 Other medical care
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.992 0.008 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.983 0.017 0.000
Chapter X Diseases of the respiratory system
0.982 0.018 0.000
M20-M25 Other joint disorders
0.982 0.018 0.000
Z51.2 Other chemotherapy
0.982 0.018 0.000
Chapter II Neoplasms
0.980 0.020 0.000
Z51.5 Palliative care
0.979 0.021 0.000
Chapter I Certain infectious and parasitic diseases
0.978 0.022 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.977 0.023 0.000
Chapter XIV Diseases of the genitourinary system
0.974 0.026 0.000
Chapter VIII Diseases of the ear and mastoid process
0.974 0.026 0.000
T81 Complications of procedures, not elsewhere classified
0.972 0.028 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.970 0.030 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.953 0.047 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.951 0.049 0.000
Z51.0 Radiotherapy session
0.951 0.049 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.939 0.061 0.000
R59 Enlarged lymph nodes
0.939 0.061 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.938 0.062 0.000
G40-G47 Episodic and paroxysmal disorders
0.937 0.063 0.000
J20-J22 Other acute lower respiratory infections
0.935 0.065 0.000
J00-J06 Acute upper respiratory infections
0.933 0.067 0.000
M05-M14 Inflammatory polyarthropathies
0.929 0.071 0.000
H65-H75 Diseases of middle ear and mastoid
0.928 0.072 0.000
G40 Epilepsy
0.924 0.076 0.000
M25 Other joint disorders, not elsewhere classified
0.923 0.077 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.915 0.085 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.913 0.087 0.000
S80-S89 Injuries to the knee and lower leg
0.913 0.087 0.000
G90-G99 Other disorders of the nervous system
0.909 0.091 0.000
R52 Pain, not elsewhere classified
0.909 0.091 0.000
R18 Ascites
0.908 0.092 0.000
R53 Malaise and fatigue
0.907 0.093 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.907 0.093 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.906 0.093 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.906 0.094 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.904 0.096 0.000
M70-M79 Other soft tissue disorders
0.902 0.098 0.000
J22 Unspecified acute lower respiratory infection
0.901 0.099 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.901 0.099 0.000
Y95 Nosocomial condition
0.899 0.101 0.000
Chapter IX Diseases of the circulatory system
0.899 0.101 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.897 0.103 0.000
M25.5 Pain in joint
0.890 0.110 0.000
R59.0 Localised enlarged lymph nodes
0.888 0.112 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.887 0.113 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.886 0.114 0.000
J30-J39 Other diseases of upper respiratory tract
0.886 0.114 0.000
A00-A09 Intestinal infectious diseases
0.885 0.115 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.885 0.115 0.000
Z51.8 Other specified medical care
0.879 0.120 0.000
R20 Disturbances of skin sensation
0.879 0.121 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.879 0.121 0.000
R45 Symptoms and signs involving emotional state
0.876 0.124 0.000
J02 Acute pharyngitis
0.876 0.124 0.000
N60-N64 Disorders of breast
0.875 0.125 0.000
R14 Flatulence and related conditions
0.873 0.127 0.000
G40.9 Epilepsy, unspecified
0.864 0.136 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.863 0.137 0.000
Z51.3 Blood transfusion without reported diagnosis
0.862 0.138 0.000
B95-B98 Bacterial, viral and other infectious agents
0.861 0.139 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.861 0.139 0.000
Chapter XXII Codes for special purposes
0.858 0.142 0.000
M22 Disorders of patella
0.858 0.142 0.000
R60 Oedema, not elsewhere classified
0.853 0.147 0.000
R42 Dizziness and giddiness
0.851 0.149 0.000
R20.2 Paraesthesia of skin
0.848 0.152 0.000
Y83.3 Surgical operation with formation of external stoma
0.848 0.152 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.847 0.153 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.847 0.153 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.847 0.153 0.000
R15 Faecal incontinence
0.844 0.156 0.000
M20 Acquired deformities of fingers and toes
0.842 0.158 0.000
Z40 Prophylactic surgery
0.840 0.160 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.839 0.161 0.000
T42.4 Benzodiazepines
0.838 0.162 0.000
R47-R49 Symptoms and signs involving speech and voice
0.837 0.163 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.837 0.163 0.000
I30-I52 Other forms of heart disease
0.836 0.164 0.000
C50-C50 Malignant neoplasm of breast
0.836 0.164 0.000
J02.9 Acute pharyngitis, unspecified
0.835 0.165 0.000
N30-N39 Other diseases of urinary system
0.834 0.165 0.000
R50 Fever of unknown origin
0.834 0.166 0.000
J33 Nasal polyp
0.833 0.167 0.000
N00-N08 Glomerular diseases
0.829 0.171 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.827 0.173 0.000
M06 Other rheumatoid arthritis
0.827 0.173 0.000
Z51.1 Chemotherapy session for neoplasm
0.824 0.176 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.823 0.177 0.000
G20-G26 Extrapyramidal and movement disorders
0.823 0.177 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.822 0.178 0.000
M75 Shoulder lesions
0.819 0.181 0.000
M86-M90 Other osteopathies
0.817 0.183 0.000
S82 Fracture of lower leg, including ankle
0.815 0.185 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.815 0.185 0.000
D10-D36 Benign neoplasms
0.814 0.186 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.813 0.187 0.000
R94 Abnormal results of function studies
0.809 0.191 0.000
R68 Other general symptoms and signs
0.808 0.192 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.808 0.192 0.000
G93 Other disorders of brain
0.807 0.193 0.000
I35 Nonrheumatic aortic valve disorders
0.807 0.193 0.000
N25-N29 Other disorders of kidney and ureter
0.806 0.194 0.000
M24 Other specific joint derangements
0.806 0.194 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.805 0.195 0.000
R17 Unspecified jaundice
0.804 0.196 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.803 0.197 0.000
D70 Agranulocytosis
0.803 0.197 0.000
J60-J70 Lung diseases due to external agents
0.803 0.197 0.000
T51 Toxic effect of alcohol
0.802 0.198 0.000
R11 Nausea and vomiting
0.799 0.201 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.799 0.201 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.799 0.201 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.798 0.202 0.000
J03 Acute tonsillitis
0.797 0.203 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.796 0.204 0.000
Z42 Follow-up care involving plastic surgery
0.796 0.204 0.000
Z43 Attention to artificial openings
0.795 0.205 0.000
H80-H83 Diseases of inner ear
0.795 0.205 0.000
W20-W49 Exposure to inanimate mechanical forces
0.793 0.207 0.000
M07 Psoriatic and enteropathic arthropathies
0.792 0.208 0.000
R52.1 Chronic intractable pain
0.792 0.208 0.000
N60 Benign mammary dysplasia
0.791 0.209 0.000
R41.0 Disorientation, unspecified
0.791 0.209 0.000
Y40 Systemic antibiotics
0.791 0.209 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.791 0.209 0.000
M80-M85 Disorders of bone density and structure
0.790 0.210 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.790 0.210 0.000
Z45 Adjustment and management of implanted device
0.789 0.211 0.000
Z41 Procedures for purposes other than remedying health state
0.789 0.211 0.000
J33.8 Other polyp of sinus
0.789 0.211 0.000
R57 Shock, not elsewhere classified
0.788 0.212 0.000
V20-V29 Motorcycle rider injured in transport accident
0.787 0.212 0.000
Y83.5 Amputation of limb(s)
0.785 0.215 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.784 0.216 0.000
H66 Suppurative and unspecified otitis media
0.784 0.216 0.000
M21 Other acquired deformities of limbs
0.782 0.218 0.000
H72 Perforation of tympanic membrane
0.781 0.219 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.781 0.219 0.000
R52.2 Other chronic pain
0.781 0.219 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.779 0.221 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.778 0.222 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.777 0.223 0.000
M25.56 Pain in joint (Lower leg)
0.776 0.224 0.000
R94.5 Abnormal results of liver function studies
0.773 0.227 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.773 0.227 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.773 0.227 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.772 0.228 0.000
G30-G32 Other degenerative diseases of the nervous system
0.772 0.228 0.000
H60-H62 Diseases of external ear
0.771 0.229 0.000
S60-S69 Injuries to the wrist and hand
0.771 0.229 0.000
R56 Convulsions, not elsewhere classified
0.770 0.230 0.000
M22.4 Chondromalacia patellae
0.769 0.231 0.000
Y83.6 Removal of other organ (partial) (total)
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.768 0.232 0.000
D69 Purpura and other haemorrhagic conditions
0.766 0.234 0.000
R54 Senility
0.765 0.235 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.764 0.236 0.000
M25.50 Pain in joint (Multiple sites)
0.763 0.237 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.761 0.239 0.000
M00-M03 Infectious arthropathies
0.760 0.240 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.760 0.240 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.759 0.241 0.000
C91 Lymphoid leukaemia
0.758 0.242 0.000
H65 Nonsuppurative otitis media
0.758 0.242 0.000
Y43 Primarily systemic agents
0.757 0.243 0.000
R41.3 Other amnesia
0.757 0.243 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.757 0.243 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.756 0.244 0.000
N73 Other female pelvic inflammatory diseases
0.756 0.244 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.755 0.245 0.000
D50-D53 Nutritional anaemias
0.755 0.245 0.000
R59.9 Enlarged lymph nodes, unspecified
0.755 0.245 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.754 0.246 0.000
M06.9 Rheumatoid arthritis, unspecified
0.754 0.246 0.000
E10-E14 Diabetes mellitus
0.753 0.247 0.000
S50-S59 Injuries to the elbow and forearm
0.752 0.248 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.749 0.251 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.748 0.252 0.000
H73 Other disorders of tympanic membrane
0.748 0.252 0.000
M25.53 Pain in joint (Forearm)
0.747 0.253 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.747 0.253 0.000
N17-N19 Renal failure
0.747 0.253 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.747 0.253 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.746 0.254 0.000
S81 Open wound of lower leg
0.745 0.254 0.000
M50-M54 Other dorsopathies
0.745 0.255 0.000
M75.0 Adhesive capsulitis of shoulder
0.743 0.257 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.742 0.258 0.000
G56 Mononeuropathies of upper limb
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.742 0.258 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.741 0.259 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.741 0.259 0.000
R47 Speech disturbances, not elsewhere classified
0.741 0.259 0.000
N84 Polyp of female genital tract
0.740 0.260 0.000
I34 Nonrheumatic mitral valve disorders
0.740 0.260 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.740 0.260 0.000
M25.57 Pain in joint (Ankle and foot)
0.738 0.262 0.000
S82.6 Fracture of lateral malleolus
0.736 0.264 0.000
N72 Inflammatory disease of cervix uteri
0.736 0.264 0.000
H90-H95 Other disorders of ear
0.735 0.265 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.735 0.265 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.735 0.265 0.000
D60-D64 Aplastic and other anaemias
0.735 0.265 0.000
A08 Viral and other specified intestinal infections
0.734 0.266 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.733 0.267 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.733 0.267 0.000
R21 Rash and other nonspecific skin eruption
0.732 0.268 0.000
C50 Malignant neoplasm of breast
0.732 0.268 0.000
D80-D89 Certain disorders involving the immune mechanism
0.732 0.268 0.000
R40 Somnolence, stupor and coma
0.731 0.269 0.000
Y52 Agents primarily affecting the cardiovascular system
0.730 0.270 0.000
B02 Zoster [herpes zoster]
0.728 0.271 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.728 0.272 0.000
Z40.8 Other prophylactic surgery
0.728 0.272 0.000
R45.2 Unhappiness
0.727 0.273 0.000
B07 Viral warts
0.727 0.273 0.000
T39.1 4-Aminophenol derivatives
0.727 0.273 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.726 0.274 0.000
C15-C26 Malignant neoplasms of digestive organs
0.725 0.274 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.725 0.275 0.000
A80-A89 Viral infections of the central nervous system
0.725 0.275 0.000
J09-J18 Influenza and pneumonia
0.725 0.275 0.000
J36 Peritonsillar abscess
0.725 0.275 0.000
T66-T78 Other and unspecified effects of external causes
0.724 0.276 0.000
I35.0 Aortic (valve) stenosis
0.724 0.276 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.724 0.276 0.000
I95 Hypotension
0.723 0.277 0.000
L50-L54 Urticaria and erythema
0.722 0.278 0.000
R50.0 Fever with chills
0.722 0.278 0.000
B00 Herpesviral [herpes simplex] infections
0.722 0.278 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.721 0.279 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.721 0.279 0.000
L20-L30 Dermatitis and eczema
0.721 0.279 0.000
T51.0 Ethanol
0.720 0.280 0.000
C71 Malignant neoplasm of brain
0.718 0.282 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
N64 Other disorders of breast
0.717 0.283 0.000
Z51.9 Medical care, unspecified
0.716 0.284 0.000
Z51.6 Desensitisation to allergens
0.716 0.284 0.000
R45.1 Restlessness and agitation
0.716 0.284 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.716 0.284 0.000
L91 Hypertrophic disorders of skin
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.286 0.000
R62 Lack of expected normal physiological development
0.714 0.286 0.000
R64 Cachexia
0.714 0.286 0.000
R58 Haemorrhage, not elsewhere classified
0.714 0.286 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.713 0.287 0.000
Z54 Convalescence
0.713 0.287 0.000
Z52 Donors of organs and tissues
0.713 0.287 0.000
Z49 Care involving dialysis
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
D27 Benign neoplasm of ovary
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.287 0.000
T86 Failure and rejection of transplanted organs and tissues
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.287 0.000
N92 Excessive, frequent and irregular menstruation
0.710 0.290 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.709 0.291 0.000
J00 Acute nasopharyngitis [common cold]
0.707 0.293 0.000
D18 Haemangioma and lymphangioma, any site
0.707 0.293 0.000
J95-J99 Other diseases of the respiratory system
0.707 0.293 0.000
R46 Symptoms and signs involving appearance and behaviour
0.705 0.295 0.000
R43 Disturbances of smell and taste
0.705 0.295 0.000
B35-B49 Mycoses
0.705 0.295 0.000
D46 Myelodysplastic syndromes
0.704 0.296 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
M34 Systemic sclerosis
0.704 0.296 0.000
M33 Dermatopolymyositis
0.704 0.296 0.000
M32 Systemic lupus erythematosus
0.704 0.296 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.296 0.000
M05 Seropositive rheumatoid arthritis
0.704 0.296 0.000
S00-S09 Injuries to the head
0.703 0.297 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.703 0.297 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.297 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
N10-N16 Renal tubulo-interstitial diseases
0.700 0.300 0.000
J03.9 Acute tonsillitis, unspecified
0.700 0.300 0.000
M76 Enthesopathies of lower limb, excluding foot
0.700 0.300 0.000
J32 Chronic sinusitis
0.700 0.300 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.699 0.301 0.000
C92 Myeloid leukaemia
0.699 0.301 0.000
R60.0 Localised oedema
0.698 0.302 0.000
G91 Hydrocephalus
0.698 0.302 0.000
T90 Sequelae of injuries of head
0.698 0.302 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.697 0.303 0.000
T81.9 Unspecified complication of procedure
0.697 0.303 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.697 0.303 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.697 0.303 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.697 0.303 0.000
L40-L45 Papulosquamous disorders
0.696 0.304 0.000
M13 Other arthritis
0.696 0.304 0.000
D55-D59 Haemolytic anaemias
0.695 0.305 0.000
I35.1 Aortic (valve) insufficiency
0.695 0.305 0.000
M31 Other necrotising vasculopathies
0.695 0.305 0.000
M07.3 Other psoriatic arthropathies
0.694 0.306 0.000
D00-D09 In situ neoplasms
0.693 0.307 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.693 0.307 0.000
N75 Diseases of Bartholin's gland
0.693 0.307 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.693 0.307 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.307 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.693 0.307 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.307 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T36 Poisoning by systemic antibiotics
0.693 0.307 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.693 0.307 0.000
G56.0 Carpal tunnel syndrome
0.692 0.308 0.000
R60.9 Oedema, unspecified
0.691 0.309 0.000
N32 Other disorders of bladder
0.691 0.309 0.000
E10 Insulin-dependent diabetes mellitus
0.690 0.310 0.000
D25 Leiomyoma of uterus
0.689 0.311 0.000
Y40.0 Penicillins
0.688 0.312 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.688 0.312 0.000
Z45.2 Adjustment and management of vascular access device
0.688 0.312 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.687 0.313 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.687 0.313 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.687 0.313 0.000
R61 Hyperhidrosis
0.687 0.313 0.000
C51-C58 Malignant neoplasms of female genital organs
0.686 0.314 0.000
H71 Cholesteatoma of middle ear
0.686 0.314 0.000
S70-S79 Injuries to the hip and thigh
0.684 0.316 0.000
N70 Salpingitis and oophoritis
0.684 0.316 0.000
D24 Benign neoplasm of breast
0.684 0.316 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.683 0.317 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.682 0.317 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.682 0.318 0.000
E20-E35 Disorders of other endocrine glands
0.682 0.318 0.000
G60 Hereditary and idiopathic neuropathy
0.681 0.319 0.000
M24.1 Other articular cartilage disorders
0.680 0.320 0.000
S82.60 Fracture of lateral malleolus (closed)
0.680 0.320 0.000
Z46 Fitting and adjustment of other devices
0.679 0.321 0.000
R45.8 Other symptoms and signs involving emotional state
0.679 0.321 0.000
D72 Other disorders of white blood cells
0.679 0.321 0.000
E50-E64 Other nutritional deficiencies
0.679 0.321 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.678 0.322 0.000
G93.8 Other specified disorders of brain
0.678 0.322 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.678 0.322 0.000
N84.0 Polyp of corpus uteri
0.677 0.323 0.000
C79 Secondary malignant neoplasm of other sites
0.676 0.323 0.000
N87 Dysplasia of cervix uteri
0.676 0.323 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.676 0.324 0.000
S20-S29 Injuries to the thorax
0.676 0.324 0.000
Q50-Q56 Congenital malformations of genital organs
0.676 0.324 0.000
R12 Heartburn
0.676 0.324 0.000
I38 Endocarditis, valve unspecified
0.676 0.324 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.676 0.324 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.676 0.324 0.000
M20.4 Other hammer toe(s) (acquired)
0.675 0.325 0.000
J69 Pneumonitis due to solids and liquids
0.674 0.326 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.673 0.326 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.673 0.326 0.000
Y98 Lifestyle-related condition
0.673 0.326 0.000
Y97 Environmental-pollution-related condition
0.673 0.326 0.000
Y96 Work-related condition
0.673 0.326 0.000
C50.9 Breast, unspecified
0.673 0.327 0.000
H83 Other diseases of inner ear
0.672 0.328 0.000
H66.9 Otitis media, unspecified
0.672 0.328 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
I80 Phlebitis and thrombophlebitis
0.672 0.328 0.000
C91.1 Chronic lymphocytic leukaemia
0.672 0.328 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.671 0.328 0.000
G41 Status epilepticus
0.671 0.328 0.000
I60-I69 Cerebrovascular diseases
0.671 0.329 0.000
N99-N99 Other disorders of the genitourinary system
0.671 0.329 0.000
J21 Acute bronchiolitis
0.670 0.329 0.000
J20 Acute bronchitis
0.670 0.329 0.000
M40-M43 Deforming dorsopathies
0.670 0.329 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.670 0.330 0.000
M11 Other crystal arthropathies
0.670 0.330 0.000
I46 Cardiac arrest
0.670 0.330 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.669 0.331 0.000
J04 Acute laryngitis and tracheitis
0.669 0.331 0.000
J01 Acute sinusitis
0.669 0.331 0.000
R23 Other skin changes
0.669 0.331 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.668 0.332 0.000
N76 Other inflammation of vagina and vulva
0.668 0.332 0.000
D47.2 Monoclonal gammopathy
0.668 0.332 0.000
S82.0 Fracture of patella
0.668 0.332 0.000
M75.5 Bursitis of shoulder
0.666 0.334 0.000
M14 Arthropathies in other diseases classified elsewhere
0.666 0.334 0.000
M12 Other specific arthropathies
0.666 0.334 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.666 0.334 0.000
M08 Juvenile arthritis
0.666 0.334 0.000
J35 Chronic diseases of tonsils and adenoids
0.666 0.334 0.000
G25 Other extrapyramidal and movement disorders
0.666 0.334 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.665 0.335 0.000
H74 Other disorders of middle ear and mastoid
0.665 0.335 0.000
H70 Mastoiditis and related conditions
0.665 0.335 0.000
H69 Other disorders of Eustachian tube
0.665 0.335 0.000
H68 Eustachian salpingitis and obstruction
0.665 0.335 0.000
H67 Otitis media in diseases classified elsewhere
0.665 0.335 0.000
V10-V19 Pedal cyclist injured in transport accident
0.665 0.335 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
N61 Inflammatory disorders of breast
0.664 0.336 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.663 0.337 0.000
G40.8 Other epilepsy
0.662 0.338 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.662 0.338 0.000
G40.5 Special epileptic syndromes
0.662 0.338 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.662 0.338 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.662 0.338 0.000
I34.0 Mitral (valve) insufficiency
0.662 0.338 0.000
M25.9 Joint disorder, unspecified
0.661 0.338 0.000
M25.8 Other specified joint disorders
0.661 0.338 0.000
M25.3 Other instability of joint
0.661 0.338 0.000
M25.2 Flail joint
0.661 0.338 0.000
M25.1 Fistula of joint
0.661 0.338 0.000
M25.0 Haemarthrosis
0.661 0.338 0.000
Y83.9 Surgical procedure, unspecified
0.661 0.339 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.661 0.339 0.000
M77 Other enthesopathies
0.660 0.339 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.660 0.340 0.000
N39 Other disorders of urinary system
0.660 0.340 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.660 0.340 0.000
A04 Other bacterial intestinal infections
0.659 0.341 0.000
R51 Headache
0.658 0.342 0.000
J39 Other diseases of upper respiratory tract
0.658 0.342 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.657 0.343 0.000
L89 Decubitus ulcer
0.657 0.343 0.000
D75 Other diseases of blood and blood-forming organs
0.657 0.343 0.000
Y83.0 Surgical operation with transplant of whole organ
0.656 0.344 0.000
L91.8 Other hypertrophic disorders of skin
0.655 0.345 0.000
D10 Benign neoplasm of mouth and pharynx
0.655 0.345 0.000
L10-L14 Bullous disorders
0.654 0.345 0.000
D73 Diseases of spleen
0.654 0.346 0.000
S88 Traumatic amputation of lower leg
0.654 0.346 0.000
S87 Crushing injury of lower leg
0.654 0.346 0.000
S86 Injury of muscle and tendon at lower leg level
0.654 0.346 0.000
S85 Injury of blood vessels at lower leg level
0.654 0.346 0.000
S84 Injury of nerves at lower leg level
0.654 0.346 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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