TreeWAS – Variant ID: rs28780107

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	0.998	0.002	0.000
Chapter II Neoplasms	0.998	0.002	0.000
Chapter XI Diseases of the digestive system	0.998	0.002	0.000
K80 Cholelithiasis	0.997	0.003	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.997	0.003	0.000
L40-L45 Papulosquamous disorders	0.997	0.003	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.996	0.004	0.000
Chapter V Mental and behavioural disorders	0.995	0.005	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.995	0.005	0.000
E03 Other hypothyroidism	0.001	0.006	0.993
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.992	0.008	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.992	0.008	0.000
E00-E07 Disorders of thyroid gland	0.002	0.009	0.989
T43.2 Other and unspecified antidepressants	0.990	0.010	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.988	0.012	0.000
Chapter XX External causes of morbidity and mortality	0.986	0.014	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.001	0.014	0.986
K80.1 Calculus of gallbladder with other cholecystitis	0.986	0.014	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.019	0.981
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.976	0.024	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.974	0.026	0.000
C15-C26 Malignant neoplasms of digestive organs	0.972	0.028	0.000
G62 Other polyneuropathies	0.970	0.030	0.000
K70-K77 Diseases of liver	0.970	0.030	0.000
W20-W49 Exposure to inanimate mechanical forces	0.966	0.034	0.000
F30-F39 Mood [affective] disorders	0.962	0.038	0.000
K80.4 Calculus of bile duct with cholecystitis	0.954	0.046	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.954	0.046	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.951	0.049	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.931	0.052	0.017
G62.9 Polyneuropathy, unspecified	0.948	0.052	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.947	0.053	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.944	0.056	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.943	0.057	0.000
W22 Striking against or struck by other objects	0.939	0.061	0.000
L40.0 Psoriasis vulgaris	0.931	0.069	0.000
C79 Secondary malignant neoplasm of other sites	0.928	0.072	0.000
G20-G26 Extrapyramidal and movement disorders	0.928	0.072	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.925	0.075	0.000
W22.9 Unspecified place	0.920	0.080	0.000
C78.7 Secondary malignant neoplasm of liver	0.919	0.081	0.000
Chapter VIII Diseases of the ear and mastoid process	0.917	0.083	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.915	0.085	0.000
Chapter XIV Diseases of the genitourinary system	0.912	0.088	0.000
E70-E90 Metabolic disorders	0.911	0.089	0.000
M05-M14 Inflammatory polyarthropathies	0.910	0.090	0.000
M70-M79 Other soft tissue disorders	0.909	0.091	0.000
K90.0 Coeliac disease	0.000	0.093	0.907
M07 Psoriatic and enteropathic arthropathies	0.905	0.094	0.000
M07.3 Other psoriatic arthropathies	0.903	0.097	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.902	0.098	0.000
C78.2 Secondary malignant neoplasm of pleura	0.900	0.100	0.000
N20-N23 Urolithiasis	0.898	0.102	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.897	0.103	0.000
T39.1 4-Aminophenol derivatives	0.896	0.104	0.000
M45-M49 Spondylopathies	0.895	0.105	0.000
N20 Calculus of kidney and ureter	0.894	0.106	0.000
C64-C68 Malignant neoplasms of urinary tract	0.891	0.109	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.890	0.110	0.000
G40-G47 Episodic and paroxysmal disorders	0.887	0.113	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.884	0.116	0.000
N20.1 Calculus of ureter	0.884	0.116	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.883	0.117	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.881	0.119	0.000
G70-G73 Diseases of myoneural junction and muscle	0.879	0.121	0.000
F31 Bipolar affective disorder	0.877	0.123	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.876	0.123	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.125	0.875
M40-M43 Deforming dorsopathies	0.873	0.127	0.000
K70 Alcoholic liver disease	0.873	0.127	0.000
N30-N39 Other diseases of urinary system	0.872	0.128	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.871	0.129	0.000
F32 Depressive episode	0.871	0.129	0.000
E78.0 Pure hypercholesterolaemia	0.869	0.131	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.867	0.133	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.864	0.136	0.000
K76 Other diseases of liver	0.864	0.136	0.000
G24 Dystonia	0.863	0.137	0.000
M46 Other inflammatory spondylopathies	0.862	0.138	0.000
N10-N16 Renal tubulo-interstitial diseases	0.861	0.139	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.861	0.139	0.000
C34 Malignant neoplasm of bronchus and lung	0.857	0.143	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.856	0.144	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.853	0.147	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.853	0.147	0.000
X50-X57 Overexertion, travel and privation	0.852	0.148	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.848	0.152	0.000
S32 Fracture of lumbar spine and pelvis	0.844	0.156	0.000
H80-H83 Diseases of inner ear	0.842	0.158	0.000
G61 Inflammatory polyneuropathy	0.841	0.159	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.840	0.160	0.000
K08 Other disorders of teeth and supporting structures	0.840	0.160	0.000
E06 Thyroiditis	0.001	0.160	0.839
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.836	0.164	0.000
V10-V19 Pedal cyclist injured in transport accident	0.835	0.165	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.834	0.166	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.833	0.167	0.000
N20.0 Calculus of kidney	0.832	0.168	0.000
K81 Cholecystitis	0.830	0.170	0.000
W44 Foreign body entering into or through eye or natural orifice	0.830	0.170	0.000
F60-F69 Disorders of adult personality and behaviour	0.829	0.171	0.000
C18 Malignant neoplasm of colon	0.826	0.174	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.823	0.177	0.000
N13 Obstructive and reflux uropathy	0.821	0.179	0.000
G62.8 Other specified polyneuropathies	0.819	0.180	0.000
E87.2 Acidosis	0.818	0.182	0.000
Y43 Primarily systemic agents	0.816	0.184	0.000
M77 Other enthesopathies	0.816	0.184	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.815	0.185	0.000
C15 Malignant neoplasm of oesophagus	0.812	0.188	0.000
C78.0 Secondary malignant neoplasm of lung	0.812	0.188	0.000
S31 Open wound of abdomen, lower back and pelvis	0.811	0.189	0.000
C16 Malignant neoplasm of stomach	0.811	0.189	0.000
K11 Diseases of salivary glands	0.808	0.191	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.808	0.192	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.807	0.193	0.000
H65-H75 Diseases of middle ear and mastoid	0.807	0.193	0.000
F41 Other anxiety disorders	0.807	0.193	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.806	0.194	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.803	0.197	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.802	0.198	0.000
K83 Other diseases of biliary tract	0.802	0.198	0.000
L40.8 Other psoriasis	0.800	0.200	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.797	0.203	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.795	0.205	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.794	0.206	0.000
S10-S19 Injuries to the neck	0.794	0.206	0.000
C17 Malignant neoplasm of small intestine	0.792	0.208	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.788	0.212	0.000
G40 Epilepsy	0.788	0.212	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.787	0.213	0.000
C18.7 Sigmoid colon	0.787	0.213	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.787	0.213	0.000
M71 Other bursopathies	0.787	0.213	0.000
G24.9 Dystonia, unspecified	0.783	0.217	0.000
C80 Malignant neoplasm without specification of site	0.781	0.219	0.000
M60-M63 Disorders of muscles	0.780	0.220	0.000
K72 Hepatic failure, not elsewhere classified	0.780	0.220	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.779	0.220	0.000
K10 Other diseases of jaws	0.777	0.223	0.000
F30 Manic episode	0.777	0.223	0.000
C22.9 Liver, unspecified	0.776	0.224	0.000
G70 Myasthenia gravis and other myoneural disorders	0.775	0.225	0.000
H83 Other diseases of inner ear	0.775	0.225	0.000
M86-M90 Other osteopathies	0.775	0.225	0.000
F17.1 Harmful use	0.773	0.227	0.000
C32 Malignant neoplasm of larynx	0.772	0.228	0.000
E07 Other disorders of thyroid	0.001	0.229	0.769
T42.4 Benzodiazepines	0.771	0.229	0.000
S60-S69 Injuries to the wrist and hand	0.768	0.232	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.764	0.236	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.764	0.236	0.000
W50-W64 Exposure to animate mechanical forces	0.764	0.236	0.000
K75 Other inflammatory liver diseases	0.761	0.239	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.761	0.239	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.759	0.241	0.000
Q60-Q64 Congenital malformations of the urinary system	0.758	0.242	0.000
K81.0 Acute cholecystitis	0.757	0.243	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.757	0.243	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.756	0.244	0.000
C09 Malignant neoplasm of tonsil	0.753	0.247	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.753	0.247	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.752	0.247	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.752	0.248	0.000
F99-F99 Unspecified mental disorder	0.752	0.248	0.000
M41 Scoliosis	0.749	0.251	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.749	0.251	0.000
K35-K38 Diseases of appendix	0.748	0.252	0.000
C22.1 Intrahepatic bile duct carcinoma	0.747	0.253	0.000
G90-G99 Other disorders of the nervous system	0.747	0.253	0.000
E10-E14 Diabetes mellitus	0.731	0.254	0.015
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.746	0.254	0.000
F45 Somatoform disorders	0.745	0.255	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.745	0.255	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.744	0.256	0.000
C34.3 Lower lobe, bronchus or lung	0.744	0.256	0.000
E87.5 Hyperkalaemia	0.743	0.257	0.000
Y57 Other and unspecified drugs and medicaments	0.742	0.258	0.000
X60-X84 Intentional self-harm	0.742	0.258	0.000
F42 Obsessive-compulsive disorder	0.741	0.259	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.741	0.259	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.740	0.259	0.000
F41.9 Anxiety disorder, unspecified	0.741	0.259	0.000
M00-M03 Infectious arthropathies	0.738	0.262	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.738	0.262	0.000
Y43.3 Other antineoplastic drugs	0.736	0.264	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.736	0.264	0.000
S70-S79 Injuries to the hip and thigh	0.736	0.264	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.735	0.265	0.000
Q50-Q56 Congenital malformations of genital organs	0.734	0.266	0.000
W44.0 Home	0.733	0.267	0.000
E06.3 Autoimmune thyroiditis	0.001	0.268	0.731
K70.3 Alcoholic cirrhosis of liver	0.732	0.268	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.731	0.269	0.000
T39.0 Salicylates	0.730	0.270	0.000
K08.3 Retained dental root	0.728	0.272	0.000
W25 Contact with sharp glass	0.728	0.272	0.000
C24.0 Extrahepatic bile duct	0.728	0.272	0.000
K70.4 Alcoholic hepatic failure	0.727	0.273	0.000
K70.1 Alcoholic hepatitis	0.727	0.273	0.000
H83.0 Labyrinthitis	0.727	0.273	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.726	0.274	0.000
M43 Other deforming dorsopathies	0.725	0.275	0.000
M75 Shoulder lesions	0.724	0.276	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.722	0.278	0.000
K14 Diseases of tongue	0.721	0.279	0.000
H72 Perforation of tympanic membrane	0.721	0.279	0.000
T79-T79 Certain early complications of trauma	0.720	0.280	0.000
Chapter I Certain infectious and parasitic diseases	0.720	0.280	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.719	0.281	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.719	0.281	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
T36 Poisoning by systemic antibiotics	0.717	0.283	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.717	0.283	0.000
T92 Sequelae of injuries of upper limb	0.716	0.284	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284	0.000
K80.3 Calculus of bile duct with cholangitis	0.715	0.285	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.715	0.285	0.000
D68 Other coagulation defects	0.715	0.285	0.000
L44 Other papulosquamous disorders	0.715	0.285	0.000
L41 Parapsoriasis	0.715	0.285	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.715	0.285	0.000
L42 Pityriasis rosea	0.715	0.285	0.000
L10-L14 Bullous disorders	0.714	0.286	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286	0.000
F70-F79 Mental retardation	0.714	0.286	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.713	0.287	0.000
T43.9 Psychotropic drug, unspecified	0.713	0.287	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.713	0.287	0.000
T43.6 Psychostimulants with abuse potential	0.713	0.287	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.713	0.287	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.713	0.287	0.000
E03.8 Other specified hypothyroidism	0.001	0.287	0.712
E03.5 Myxoedema coma	0.001	0.287	0.712
E03.4 Atrophy of thyroid (acquired)	0.001	0.287	0.712
E03.3 Postinfectious hypothyroidism	0.001	0.287	0.712
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.287	0.712
E03.1 Congenital hypothyroidism without goitre	0.001	0.287	0.712
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.287	0.712
F32.0 Mild depressive episode	0.712	0.288	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.712	0.288	0.000
G24.3 Spasmodic torticollis	0.712	0.288	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.712	0.288	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.711	0.288	0.000
S80-S89 Injuries to the knee and lower leg	0.711	0.289	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.711	0.289	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.711	0.289	0.000
E88 Other metabolic disorders	0.711	0.289	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.289	0.709
E00 Congenital iodine-deficiency syndrome	0.002	0.289	0.709
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.289	0.709
F60 Specific personality disorders	0.709	0.291	0.000
C22.0 Liver cell carcinoma	0.709	0.291	0.000
S31.4 Open wound of vagina and vulva	0.709	0.291	0.000
G60 Hereditary and idiopathic neuropathy	0.708	0.291	0.000
G64 Other disorders of peripheral nervous system	0.708	0.292	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.707	0.293	0.000
K83.1 Obstruction of bile duct	0.707	0.293	0.000
Y35-Y36 Legal intervention and operations of war	0.707	0.293	0.000
Y10-Y34 Event of undetermined intent	0.707	0.293	0.000
Y00-Y09 Assault	0.707	0.293	0.000
X85-X99 Assault	0.707	0.293	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.707	0.293	0.000
X30-X39 Exposure to forces of nature	0.707	0.293	0.000
X20-X29 Contact with venomous animals and plants	0.707	0.293	0.000
X10-X19 Contact with heat and hot substances	0.707	0.293	0.000
X00-X09 Exposure to smoke, fire and flames	0.707	0.293	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293	0.000
W75-W84 Other accidental threats to breathing	0.707	0.293	0.000
W65-W74 Accidental drowning and submersion	0.707	0.293	0.000
V98-V99 Other and unspecified transport accidents	0.707	0.293	0.000
V95-V97 Air and space transport accidents	0.707	0.293	0.000
V90-V94 Water transport accidents	0.707	0.293	0.000
V70-V79 Bus occupant injured in transport accident	0.707	0.293	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293	0.000
V40-V49 Car occupant injured in transport accident	0.707	0.293	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293	0.000
V01-V09 Pedestrian injured in transport accident	0.707	0.293	0.000
E05.8 Other thyrotoxicosis	0.001	0.293	0.707
E05.5 Thyroid crisis or storm	0.001	0.293	0.707
E05.4 Thyrotoxicosis factitia	0.001	0.293	0.707
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.293	0.707
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.293	0.707
Q80-Q89 Other congenital malformations	0.707	0.293	0.000
M77.1 Lateral epicondylitis	0.706	0.294	0.000
G20 Parkinson's disease	0.704	0.296	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.704	0.296	0.000
S90-S99 Injuries to the ankle and foot	0.703	0.296	0.000
F32.1 Moderate depressive episode	0.703	0.297	0.000
F31.9 Bipolar affective disorder, unspecified	0.703	0.297	0.000
C24.9 Biliary tract, unspecified	0.702	0.298	0.000
V20-V29 Motorcycle rider injured in transport accident	0.702	0.298	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.702	0.298	0.000
K74 Fibrosis and cirrhosis of liver	0.702	0.298	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.702	0.298	0.000
X50 Overexertion and strenuous or repetitive movements	0.702	0.298	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.701	0.299	0.000
G70.0 Myasthenia gravis	0.701	0.299	0.000
Q00-Q07 Congenital malformations of the nervous system	0.701	0.299	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.701	0.299	0.000
K76.8 Other specified diseases of liver	0.700	0.300	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.699	0.301	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.699	0.301	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.699	0.301	0.000
G61.8 Other inflammatory polyneuropathies	0.698	0.302	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.698	0.302	0.000
S32.4 Fracture of acetabulum	0.697	0.303	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.697	0.303	0.000
X51 Travel and motion	0.697	0.303	0.000
C23 Malignant neoplasm of gallbladder	0.697	0.303	0.000
F80-F89 Disorders of psychological development	0.696	0.303	0.000
C34.2 Middle lobe, bronchus or lung	0.696	0.304	0.000
N20.9 Urinary calculus, unspecified	0.696	0.304	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.696	0.304	0.000
C10 Malignant neoplasm of oropharynx	0.696	0.304	0.000
G62.2 Polyneuropathy due to other toxic agents	0.696	0.304	0.000
G62.1 Alcoholic polyneuropathy	0.696	0.304	0.000
G62.0 Drug-induced polyneuropathy	0.696	0.304	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.696	0.304	0.000
K77 Liver disorders in diseases classified elsewhere	0.696	0.304	0.000
K71 Toxic liver disease	0.696	0.304	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.694	0.306	0.000
G30-G32 Other degenerative diseases of the nervous system	0.694	0.306	0.000
S32.0 Fracture of lumbar vertebra	0.694	0.306	0.000
C16.9 Stomach, unspecified	0.694	0.306	0.000
F11 Mental and behavioural disorders due to use of opioids	0.692	0.308	0.000
W46 Contact with hypodermic needle	0.692	0.308	0.000
W45 Foreign body or object entering through skin	0.692	0.308	0.000
W43 Exposure to vibration	0.692	0.308	0.000
W42 Exposure to noise	0.692	0.308	0.000
W41 Exposure to high-pressure jet	0.692	0.308	0.000
W40 Explosion of other materials	0.692	0.308	0.000
W39 Discharge of firework	0.692	0.308	0.000
W38 Explosion and rupture of other specified pressurised devices	0.692	0.308	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.692	0.308	0.000
W36 Explosion and rupture of gas cylinder	0.692	0.308	0.000
W35 Explosion and rupture of boiler	0.692	0.308	0.000
W34 Discharge from other and unspecified firearms	0.692	0.308	0.000
W33 Rifle, shotgun and larger firearm discharge	0.692	0.308	0.000
W32 Handgun discharge	0.692	0.308	0.000
W31 Contact with other and unspecified machinery	0.692	0.308	0.000
W30 Contact with agricultural machinery	0.692	0.308	0.000
W28 Contact with powered lawn mower	0.692	0.308	0.000
W27 Contact with nonpowered hand tool	0.692	0.308	0.000
W26 Contact with knife, sword or dagger	0.692	0.308	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.692	0.308	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.692	0.308	0.000
W21 Striking against or struck by sports equipment	0.692	0.308	0.000
W20 Struck by thrown, projected or falling object	0.692	0.308	0.000
K09 Cysts of oral region, not elsewhere classified	0.692	0.308	0.000
C80.9 Malignant neoplasm, unspecified	0.692	0.308	0.000
K11.2 Sialoadenitis	0.692	0.308	0.000
K73 Chronic hepatitis, not elsewhere classified	0.692	0.308	0.000
C34.9 Bronchus or lung, unspecified	0.691	0.309	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.691	0.309	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.690	0.310	0.000
F38 Other mood [affective] disorders	0.690	0.310	0.000
F34 Persistent mood [affective] disorders	0.690	0.310	0.000
F39 Unspecified mood [affective] disorder	0.690	0.310	0.000
E20-E35 Disorders of other endocrine glands	0.683	0.311	0.006
C26 Malignant neoplasm of other and ill-defined digestive organs	0.688	0.312	0.000
H81 Disorders of vestibular function	0.687	0.313	0.000
M91-M94 Chondropathies	0.687	0.313	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.686	0.314	0.000
G25 Other extrapyramidal and movement disorders	0.685	0.315	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.685	0.315	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.684	0.315	0.000
C21 Malignant neoplasm of anus and anal canal	0.684	0.316	0.000
Q78 Other osteochondrodysplasias	0.684	0.316	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.684	0.316	0.000
S37 Injury of urinary and pelvic organs	0.684	0.316	0.000
S36 Injury of intra-abdominal organs	0.684	0.316	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.684	0.316	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.684	0.316	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.684	0.316	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.682	0.318	0.000
Q35-Q37 Cleft lip and cleft palate	0.682	0.318	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.682	0.318	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.680	0.320	0.000
D66 Hereditary factor VIII deficiency	0.680	0.320	0.000
S60 Superficial injury of wrist and hand	0.680	0.320	0.000
C66 Malignant neoplasm of ureter	0.679	0.321	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.679	0.321	0.000
M77.4 Metatarsalgia	0.679	0.321	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.679	0.321	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.679	0.321	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.679	0.321	0.000
T39.4 Antirheumatics, not elsewhere classified	0.679	0.321	0.000
T39.2 Pyrazolone derivatives	0.679	0.321	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.679	0.321	0.000
C79.2 Secondary malignant neoplasm of skin	0.679	0.321	0.000
C15.5 Lower third of oesophagus	0.678	0.322	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.678	0.322	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.678	0.322	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.677	0.323	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.677	0.323	0.000
C31 Malignant neoplasm of accessory sinuses	0.677	0.323	0.000
C37 Malignant neoplasm of thymus	0.677	0.323	0.000
C33 Malignant neoplasm of trachea	0.677	0.323	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.677	0.323	0.000
C18.1 Appendix	0.677	0.323	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.676	0.324	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.676	0.324	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.676	0.324	0.000
T42.3 Barbiturates	0.676	0.324	0.000
T42.2 Succinimides and oxazolidinediones	0.676	0.324	0.000
T42.1 Iminostilbenes	0.676	0.324	0.000
T42.0 Hydantoin derivatives	0.676	0.324	0.000
Chapter XXII Codes for special purposes	0.676	0.324	0.000
H60-H62 Diseases of external ear	0.676	0.324	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.675	0.325	0.000
D00-D09 In situ neoplasms	0.674	0.326	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.674	0.326	0.000
G71 Primary disorders of muscles	0.673	0.327	0.000
W22.8 Other specified place	0.673	0.327	0.000
W22.6 Industrial and construction area	0.673	0.327	0.000
W22.4 Street and highway	0.673	0.327	0.000
W22.0 Home	0.673	0.327	0.000
W22.7 Farm	0.673	0.327	0.000
W22.5 Trade and service area	0.673	0.327	0.000
W22.3 Sports and athletics area	0.673	0.327	0.000
W22.2 School, other institution and public administrative area	0.673	0.327	0.000
W22.1 Residential institution	0.673	0.327	0.000
K13 Other diseases of lip and oral mucosa	0.672	0.328	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.672	0.328	0.000
C01 Malignant neoplasm of base of tongue	0.672	0.328	0.000
K10.8 Other specified diseases of jaws	0.671	0.329	0.000
E78.1 Pure hyperglyceridaemia	0.671	0.329	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.671	0.329	0.000
N34 Urethritis and urethral syndrome	0.670	0.330	0.000
E40-E46 Malnutrition	0.658	0.330	0.012
G35-G37 Demyelinating diseases of the central nervous system	0.669	0.331	0.000
H66 Suppurative and unspecified otitis media	0.669	0.331	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.668	0.332	0.000
T51 Toxic effect of alcohol	0.668	0.332	0.000
N99-N99 Other disorders of the genitourinary system	0.667	0.333	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.667	0.333	0.000
B35-B49 Mycoses	0.666	0.334	0.000
G61.0 Guillain-Barre syndrome	0.666	0.334	0.000
C79.6 Secondary malignant neoplasm of ovary	0.665	0.334	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.665	0.334	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.665	0.334	0.000
G23 Other degenerative diseases of basal ganglia	0.665	0.335	0.000
G21 Secondary Parkinsonism	0.665	0.335	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.665	0.335	0.000
G22 Parkinsonism in diseases classified elsewhere	0.665	0.335	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.664	0.336	0.000
K03 Other diseases of hard tissues of teeth	0.663	0.337	0.000
C17.0 Duodenum	0.663	0.337	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.663	0.337	0.000
M76 Enthesopathies of lower limb, excluding foot	0.662	0.338	0.000
M41.9 Scoliosis, unspecified	0.660	0.340	0.000
V80-V89 Other land transport accidents	0.659	0.341	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.659	0.341	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.659	0.341	0.000
M46.4 Discitis, unspecified	0.658	0.341	0.000
N13.6 Pyonephrosis	0.658	0.342	0.000
T91 Sequelae of injuries of neck and trunk	0.658	0.342	0.000
Q76 Congenital malformations of spine and bony thorax	0.657	0.343	0.000
F48 Other neurotic disorders	0.656	0.344	0.000
F44 Dissociative [conversion] disorders	0.656	0.344	0.000
K00 Disorders of tooth development and eruption	0.655	0.345	0.000
G43 Migraine	0.655	0.345	0.000
C24.1 Ampulla of Vater	0.654	0.346	0.000
G44 Other headache syndromes	0.654	0.346	0.000
K75.8 Other specified inflammatory liver diseases	0.654	0.346	0.000
E85 Amyloidosis	0.653	0.346	0.000
E84 Cystic fibrosis	0.653	0.346	0.000
E79 Disorders of purine and pyrimidine metabolism	0.653	0.346	0.000
E77 Disorders of glycoprotein metabolism	0.653	0.346	0.000
E76 Disorders of glycosaminoglycan metabolism	0.653	0.346	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.653	0.346	0.000
E74 Other disorders of carbohydrate metabolism	0.653	0.346	0.000
E73 Lactose intolerance	0.653	0.346	0.000
E72 Other disorders of amino-acid metabolism	0.653	0.346	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.653	0.346	0.000
E70 Disorders of aromatic amino-acid metabolism	0.653	0.346	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.653	0.346	0.000
E11 Non-insulin-dependent diabetes mellitus	0.652	0.347	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations