TreeWAS – Variant ID: rs34627775

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M20-M25 Other joint disorders	0.997	0.003
Chapter II Neoplasms	0.996	0.004
Chapter IV Endocrine, nutritional and metabolic diseases	0.995	0.005
C64-C68 Malignant neoplasms of urinary tract	0.995	0.005
C67 Malignant neoplasm of bladder	0.995	0.005
E70-E90 Metabolic disorders	0.985	0.015
C67.9 Bladder, unspecified	0.984	0.016
M24 Other specific joint derangements	0.983	0.017
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.982	0.018
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.976	0.024
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.976	0.024
Chapter VIII Diseases of the ear and mastoid process	0.975	0.025
M80-M85 Disorders of bone density and structure	0.975	0.025
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.973	0.027
T36-T50 Poisoning by drugs, medicaments and biological substances	0.967	0.033
H90-H95 Other disorders of ear	0.965	0.035
C67.4 Posterior wall of bladder	0.960	0.040
H91 Other hearing loss	0.959	0.041
R93 Abnormal findings on diagnostic imaging of other body structures	0.958	0.042
H91.9 Hearing loss, unspecified	0.955	0.045
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.955	0.045
R79 Other abnormal findings of blood chemistry	0.953	0.047
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.949	0.051
T81 Complications of procedures, not elsewhere classified	0.948	0.052
R79.8 Other specified abnormal findings of blood chemistry	0.945	0.055
E86 Volume depletion	0.944	0.056
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.942	0.058
M24.1 Other articular cartilage disorders	0.940	0.060
M70-M79 Other soft tissue disorders	0.938	0.062
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.938	0.062
M25 Other joint disorders, not elsewhere classified	0.937	0.063
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.936	0.064
E10-E14 Diabetes mellitus	0.934	0.066
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.932	0.068
T15-T19 Effects of foreign body entering through natural orifice	0.927	0.073
D37-D48 Neoplasms of uncertain or unknown behaviour	0.923	0.077
M81 Osteoporosis without pathological fracture	0.923	0.077
T81.3 Disruption of operation wound, not elsewhere classified	0.922	0.078
E87 Other disorders of fluid, electrolyte and acid-base balance	0.921	0.079
R91 Abnormal findings on diagnostic imaging of lung	0.918	0.082
M85 Other disorders of bone density and structure	0.918	0.082
M31 Other necrotising vasculopathies	0.910	0.090
S40-S49 Injuries to the shoulder and upper arm	0.907	0.093
M79 Other soft tissue disorders, not elsewhere classified	0.902	0.098
R87 Abnormal findings in specimens from female genital organs	0.901	0.099
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.901	0.099
E85 Amyloidosis	0.900	0.100
M25.4 Effusion of joint	0.899	0.101
E16 Other disorders of pancreatic internal secretion	0.897	0.103
E87.2 Acidosis	0.896	0.104
M81.9 Osteoporosis, unspecified	0.894	0.106
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.887	0.113
Chapter XX External causes of morbidity and mortality	0.885	0.115
M40-M43 Deforming dorsopathies	0.884	0.116
M25.46 Effusion of joint (Lower leg)	0.882	0.118
M85.8 Other specified disorders of bone density and structure	0.878	0.122
R73 Elevated blood glucose level	0.877	0.123
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.874	0.126
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.870	0.130
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.869	0.131
E16.2 Hypoglycaemia, unspecified	0.868	0.132
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.861	0.139
T81.4 Infection following a procedure, not elsewhere classified	0.859	0.141
H90 Conductive and sensorineural hearing loss	0.859	0.141
M81.99 Osteoporosis, unspecified (Site unspecified)	0.859	0.141
R87.6 Abnormal cytological findings	0.857	0.143
M79.8 Other specified soft tissue disorders	0.850	0.150
T20-T25 Burns and corrosions of external body surface, specified by site	0.848	0.152
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.847	0.153
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.847	0.153
S10-S19 Injuries to the neck	0.843	0.157
R74 Abnormal serum enzyme levels	0.843	0.157
Q80-Q89 Other congenital malformations	0.842	0.158
E80 Disorders of porphyrin and bilirubin metabolism	0.835	0.165
C09 Malignant neoplasm of tonsil	0.833	0.167
M91-M94 Chondropathies	0.829	0.171
M21 Other acquired deformities of limbs	0.828	0.172
M60-M63 Disorders of muscles	0.827	0.173
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.825	0.175
E14 Unspecified diabetes mellitus	0.824	0.176
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.822	0.178
R73.0 Abnormal glucose tolerance test	0.822	0.178
M31.6 Other giant cell arteritis	0.819	0.181
E10 Insulin-dependent diabetes mellitus	0.819	0.181
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.818	0.182
T18 Foreign body in alimentary tract	0.816	0.184
S70-S79 Injuries to the hip and thigh	0.816	0.184
H60-H62 Diseases of external ear	0.815	0.185
T87 Complications peculiar to reattachment and amputation	0.814	0.186
T91 Sequelae of injuries of neck and trunk	0.814	0.186
E13 Other specified diabetes mellitus	0.813	0.187
Chapter VI Diseases of the nervous system	0.813	0.187
M24.16 Other articular cartilage disorders (Lower leg)	0.812	0.187
M24.0 Loose body in joint	0.811	0.189
E87.7 Fluid overload	0.810	0.190
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.810	0.190
Q38-Q45 Other congenital malformations of the digestive system	0.808	0.192
T50.9 Other and unspecified drugs, medicaments and biological substances	0.807	0.193
C67.1 Dome of bladder	0.807	0.193
C01 Malignant neoplasm of base of tongue	0.806	0.194
E85.9 Amyloidosis, unspecified	0.805	0.195
T17 Foreign body in respiratory tract	0.805	0.195
M24.2 Disorder of ligament	0.804	0.196
D00-D09 In situ neoplasms	0.802	0.198
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.800	0.200
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.800	0.200
E73 Lactose intolerance	0.799	0.201
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.797	0.203
S40 Superficial injury of shoulder and upper arm	0.794	0.206
M24.13 Other articular cartilage disorders (Forearm)	0.794	0.206
R47-R49 Symptoms and signs involving speech and voice	0.793	0.207
D48.1 Connective and other soft tissue	0.793	0.207
Q60-Q64 Congenital malformations of the urinary system	0.792	0.208
M79.80 Other specified soft tissue disorders (Multiple sites)	0.792	0.208
R78 Findings of drugs and other substances, not normally found in blood	0.791	0.209
M05-M14 Inflammatory polyarthropathies	0.790	0.210
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.785	0.215
T92 Sequelae of injuries of upper limb	0.785	0.215
Q50-Q56 Congenital malformations of genital organs	0.784	0.216
T90 Sequelae of injuries of head	0.783	0.217
C67.5 Bladder neck	0.783	0.217
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.782	0.218
M30 Polyarteritis nodosa and related conditions	0.779	0.221
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.779	0.221
M24.6 Ankylosis of joint	0.778	0.222
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.775	0.225
M79.6 Pain in limb	0.774	0.226
M81.98 Osteoporosis, unspecified (Other)	0.772	0.228
M24.4 Recurrent dislocation and subluxation of joint	0.769	0.231
W50-W64 Exposure to animate mechanical forces	0.769	0.231
E14.9 Without complications	0.768	0.232
C67.6 Ureteric orifice	0.766	0.234
M43 Other deforming dorsopathies	0.766	0.234
M22 Disorders of patella	0.763	0.237
D46 Myelodysplastic syndromes	0.759	0.241
C09.9 Tonsil, unspecified	0.759	0.241
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.758	0.242
C67.8 Overlapping lesion of bladder	0.756	0.243
C65 Malignant neoplasm of renal pelvis	0.756	0.244
T36 Poisoning by systemic antibiotics	0.756	0.244
M25.9 Joint disorder, unspecified	0.753	0.247
T84.1 Mechanical complication of internal fixation device of bones of limb	0.753	0.247
S30 Superficial injury of abdomen, lower back and pelvis	0.753	0.247
D80-D89 Certain disorders involving the immune mechanism	0.751	0.249
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.750	0.250
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.749	0.251
C67.2 Lateral wall of bladder	0.749	0.251
E40-E46 Malnutrition	0.747	0.253
R74.8 Abnormal levels of other serum enzymes	0.747	0.253
M77 Other enthesopathies	0.746	0.254
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.746	0.254
X60-X84 Intentional self-harm	0.746	0.254
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.745	0.255
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.744	0.256
H90.0 Conductive hearing loss, bilateral	0.744	0.256
M34 Systemic sclerosis	0.741	0.259
T80 Complications following infusion, transfusion and therapeutic injection	0.741	0.259
E85.4 Organ-limited amyloidosis	0.739	0.261
C67.3 Anterior wall of bladder	0.739	0.261
M79.5 Residual foreign body in soft tissue	0.739	0.261
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.738	0.262
R89 Abnormal findings in specimens from other organs, systems and tissues	0.738	0.262
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.738	0.262
S50-S59 Injuries to the elbow and forearm	0.737	0.263
T18.1 Foreign body in oesophagus	0.736	0.264
T84.3 Mechanical complication of other bone devices, implants and grafts	0.734	0.266
Chapter V Mental and behavioural disorders	0.731	0.269
T84.2 Mechanical complication of internal fixation device of other bones	0.730	0.270
E80.4 Gilbert's syndrome	0.728	0.272
G00-G09 Inflammatory diseases of the central nervous system	0.728	0.272
E13.9 Without complications	0.726	0.274
M25.8 Other specified joint disorders	0.725	0.275
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.725	0.275
X58-X59 Accidental exposure to other and unspecified factors	0.723	0.277
D06 Carcinoma in situ of cervix uteri	0.722	0.278
R87.9 Unspecified abnormal finding	0.722	0.278
M79.2 Neuralgia and neuritis, unspecified	0.721	0.279
T83.0 Mechanical complication of urinary (indwelling) catheter	0.721	0.279
C15-C26 Malignant neoplasms of digestive organs	0.720	0.280
M25.45 Effusion of joint (Pelvic region and thigh)	0.719	0.281
M00-M03 Infectious arthropathies	0.719	0.281
D45 Polycythaemia vera	0.718	0.282
Q00-Q07 Congenital malformations of the nervous system	0.718	0.282
E87.5 Hyperkalaemia	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
R86 Abnormal findings in specimens from male genital organs	0.716	0.284
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.716	0.284
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285
M33 Dermatopolymyositis	0.715	0.285
M32 Systemic lupus erythematosus	0.715	0.285
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.715	0.285
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.714	0.285
C40-C41 Malignant neoplasms of bone and articular cartilage	0.714	0.286
C05 Malignant neoplasm of palate	0.714	0.286
C68 Malignant neoplasm of other and unspecified urinary organs	0.713	0.287
C67.7 Urachus	0.713	0.287
C67.0 Trigone of bladder	0.713	0.287
R71 Abnormality of red blood cells	0.712	0.288
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.710	0.290
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.710	0.290
M79.84 Other specified soft tissue disorders (Hand)	0.710	0.290
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.710	0.290
D86 Sarcoidosis	0.710	0.290
D07 Carcinoma in situ of other and unspecified genital organs	0.709	0.291
M41 Scoliosis	0.709	0.291
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.709	0.291
R79.0 Abnormal level of blood mineral	0.708	0.291
T46 Poisoning by agents primarily affecting the cardiovascular system	0.708	0.292
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.708	0.292
E84 Cystic fibrosis	0.706	0.294
E79 Disorders of purine and pyrimidine metabolism	0.706	0.294
E77 Disorders of glycoprotein metabolism	0.706	0.294
E76 Disorders of glycosaminoglycan metabolism	0.706	0.294
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.706	0.294
E74 Other disorders of carbohydrate metabolism	0.706	0.294
E72 Other disorders of amino-acid metabolism	0.706	0.294
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.706	0.294
E70 Disorders of aromatic amino-acid metabolism	0.706	0.294
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.706	0.294
S90-S99 Injuries to the ankle and foot	0.706	0.294
Q85 Phakomatoses, not elsewhere classified	0.705	0.295
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.705	0.295
M24.9 Joint derangement, unspecified	0.705	0.295
M24.7 Protrusio acetabuli	0.705	0.295
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.705	0.295
R95-R99 Ill-defined and unknown causes of mortality	0.704	0.296
M62 Other disorders of muscle	0.704	0.296
X50-X57 Overexertion, travel and privation	0.704	0.296
M85.88 Other specified disorders of bone density and structure (Other)	0.703	0.297
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.703	0.297
G90-G99 Other disorders of the nervous system	0.702	0.298
T23 Burn and corrosion of wrist and hand	0.702	0.298
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.702	0.298
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.702	0.298
E88 Other metabolic disorders	0.702	0.298
V70-V79 Bus occupant injured in transport accident	0.701	0.299
M21.3 Wrist or foot drop (acquired)	0.700	0.300
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.700	0.300
R77 Other abnormalities of plasma proteins	0.700	0.300
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.700	0.300
M24.5 Contracture of joint	0.699	0.300
M83 Adult osteomalacia	0.699	0.301
M82 Osteoporosis in diseases classified elsewhere	0.699	0.301
M70 Soft tissue disorders related to use, overuse and pressure	0.699	0.301
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.699	0.301
T93 Sequelae of injuries of lower limb	0.698	0.302
E10.4 With neurological complications	0.697	0.303
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.697	0.303
D60-D64 Aplastic and other anaemias	0.696	0.304
M24.8 Other specific joint derangements, not elsewhere classified	0.695	0.305
S12 Fracture of neck	0.695	0.305
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.693	0.307
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.693	0.307
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.693	0.307
T41 Poisoning by anaesthetics and therapeutic gases	0.693	0.307
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.693	0.307
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.693	0.307
H80-H83 Diseases of inner ear	0.692	0.308
R84 Abnormal findings in specimens from respiratory organs and thorax	0.692	0.308
H94 Other disorders of ear in diseases classified elsewhere	0.692	0.308
R92 Abnormal findings on diagnostic imaging of breast	0.691	0.309
M79.64 Pain in limb (Hand)	0.691	0.309
R90 Abnormal findings on diagnostic imaging of central nervous system	0.690	0.310
M71 Other bursopathies	0.689	0.311
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.688	0.312
H91.3 Deaf mutism, not elsewhere classified	0.687	0.312
H91.2 Sudden idiopathic hearing loss	0.687	0.312
H91.1 Presbycusis	0.687	0.312
H91.0 Ototoxic hearing loss	0.687	0.312
R93.6 Abnormal findings on diagnostic imaging of limbs	0.687	0.313
Q60 Renal agenesis and other reduction defects of kidney	0.686	0.313
Q43 Other congenital malformations of intestine	0.685	0.315
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.685	0.315
Q35-Q37 Cleft lip and cleft palate	0.685	0.315
Q30-Q34 Congenital malformations of the respiratory system	0.685	0.315
M85.6 Other cyst of bone	0.684	0.316
S40.8 Other superficial injuries of shoulder and upper arm	0.684	0.316
M24.23 Disorder of ligament (Forearm)	0.684	0.316
M25.0 Haemarthrosis	0.681	0.319
R83 Abnormal findings in cerebrospinal fluid	0.680	0.319
T17.9 Foreign body in respiratory tract, part unspecified	0.680	0.320
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.680	0.320
M79.63 Pain in limb (Forearm)	0.679	0.321
T94 Sequelae of injuries involving multiple and unspecified body regions	0.679	0.321
T81.7 Vascular complications following a procedure, not elsewhere classified	0.679	0.321
C10 Malignant neoplasm of oropharynx	0.678	0.321
H60 Otitis externa	0.678	0.322
M25.5 Pain in joint	0.678	0.322
S31 Open wound of abdomen, lower back and pelvis	0.678	0.322
T84.0 Mechanical complication of internal joint prosthesis	0.678	0.322
E50-E64 Other nutritional deficiencies	0.678	0.322
Q63 Other congenital malformations of kidney	0.677	0.323
T98 Sequelae of other and unspecified effects of external causes	0.676	0.324
T95 Sequelae of burns, corrosions and frostbite	0.676	0.324
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.676	0.324
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.676	0.324
M25.3 Other instability of joint	0.675	0.325
M22.2 Patellofemoral disorders	0.674	0.326
M24.19 Other articular cartilage disorders (Site unspecified)	0.674	0.326
M24.18 Other articular cartilage disorders (Other)	0.674	0.326
M24.14 Other articular cartilage disorders (Hand)	0.674	0.326
M24.12 Other articular cartilage disorders (Upper arm)	0.674	0.326
M24.10 Other articular cartilage disorders (Multiple sites)	0.674	0.326
M76 Enthesopathies of lower limb, excluding foot	0.674	0.326
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.674	0.326
T91.2 Sequelae of other fracture of thorax and pelvis	0.673	0.327
M73 Soft tissue disorders in diseases classified elsewhere	0.673	0.327
E15 Nondiabetic hypoglycaemic coma	0.673	0.327
M25.2 Flail joint	0.671	0.328
M25.1 Fistula of joint	0.671	0.328
T87.4 Infection of amputation stump	0.671	0.329
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.671	0.329
C13 Malignant neoplasm of hypopharynx	0.671	0.329
C11 Malignant neoplasm of nasopharynx	0.671	0.329
C08 Malignant neoplasm of other and unspecified major salivary glands	0.671	0.329
C06 Malignant neoplasm of other and unspecified parts of mouth	0.671	0.329
C04 Malignant neoplasm of floor of mouth	0.671	0.329
C03 Malignant neoplasm of gum	0.671	0.329
C00 Malignant neoplasm of lip	0.671	0.329
C12 Malignant neoplasm of pyriform sinus	0.671	0.329
C07 Malignant neoplasm of parotid gland	0.671	0.329
G40-G47 Episodic and paroxysmal disorders	0.671	0.329
E12 Malnutrition-related diabetes mellitus	0.670	0.330
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.670	0.330
M24.07 Loose body in joint (Ankle and foot)	0.668	0.332
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.667	0.333
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.667	0.333
E73.9 Lactose intolerance, unspecified	0.666	0.334
M11 Other crystal arthropathies	0.665	0.334
V80-V89 Other land transport accidents	0.665	0.335
T19 Foreign body in genito-urinary tract	0.665	0.335
T15 Foreign body on external eye	0.665	0.335
T16 Foreign body in ear	0.665	0.335
V40-V49 Car occupant injured in transport accident	0.665	0.335
D06.9 Cervix, unspecified	0.665	0.335
T87.3 Neuroma of amputation stump	0.663	0.336
R76 Other abnormal immunological findings in serum	0.663	0.337
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.662	0.338
M81.8 Other osteoporosis	0.662	0.338
M81.6 Localised osteoporosis [Lequesne]	0.662	0.338
M81.5 Idiopathic osteoporosis	0.662	0.338
M81.3 Postsurgical malabsorption osteoporosis	0.662	0.338
M81.2 Osteoporosis of disuse	0.662	0.338
M81.1 Postoophorectomy osteoporosis	0.662	0.338
M81.0 Postmenopausal osteoporosis	0.662	0.338
M79.83 Other specified soft tissue disorders (Forearm)	0.662	0.338
M92 Other juvenile osteochondrosis	0.662	0.338
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.661	0.338
M43.0 Spondylolysis	0.661	0.339
C02 Malignant neoplasm of other and unspecified parts of tongue	0.660	0.340
E87.4 Mixed disorder of acid-base balance	0.660	0.340
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.660	0.340
S42 Fracture of shoulder and upper arm	0.659	0.340
R78.8 Finding of other specified substances, not normally found in blood	0.659	0.341
E10.3 With ophthalmic complications	0.659	0.341
X10-X19 Contact with heat and hot substances	0.658	0.342
T66-T78 Other and unspecified effects of external causes	0.658	0.342
M85.9 Disorder of bone density and structure, unspecified	0.658	0.342
M85.5 Aneurysmal bone cyst	0.658	0.342
M85.4 Solitary bone cyst	0.658	0.342
M85.3 Osteitis condensans	0.658	0.342
M85.2 Hyperostosis of skull	0.658	0.342
M85.1 Skeletal fluorosis	0.658	0.342
E10.2 With renal complications	0.658	0.342
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.657	0.343
S36 Injury of intra-abdominal organs	0.655	0.345
Y00-Y09 Assault	0.654	0.346
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.654	0.346
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.653	0.347
M31.9 Necrotising vasculopathy, unspecified	0.653	0.347
M31.8 Other specified necrotising vasculopathies	0.653	0.347
M31.7 Microscopic polyangiitis	0.653	0.347
M31.4 Aortic arch syndrome [Takayasu]	0.653	0.347
M31.2 Lethal midline granuloma	0.653	0.347
M31.1 Thrombotic microangiopathy	0.653	0.347
M31.0 Hypersensitivity angiitis	0.653	0.347
R49 Voice disturbances	0.652	0.348
S72 Fracture of femur	0.652	0.348
C49 Malignant neoplasm of other connective and soft tissue	0.651	0.348
S43.0 Dislocation of shoulder joint	0.651	0.349
S70 Superficial injury of hip and thigh	0.651	0.349
H91.8 Other specified hearing loss	0.651	0.349
S48 Traumatic amputation of shoulder and upper arm	0.650	0.350
S45 Injury of blood vessels at shoulder and upper arm level	0.650	0.350
S44 Injury of nerves at shoulder and upper arm level	0.650	0.350
S41 Open wound of shoulder and upper arm	0.650	0.350
S47 Crushing injury of shoulder and upper arm	0.650	0.350
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.650	0.350
G40 Epilepsy	0.649	0.351
M80 Osteoporosis with pathological fracture	0.649	0.351
D86.9 Sarcoidosis, unspecified	0.648	0.352
M79.9 Soft tissue disorder, unspecified	0.647	0.353
M79.4 Hypertrophy of (infrapatellar) fat pad	0.647	0.353
M79.3 Panniculitis, unspecified	0.647	0.353
T17.8 Foreign body in other and multiple parts of respiratory tract	0.646	0.353
R87.8 Other abnormal findings	0.646	0.354
R87.5 Abnormal microbiological findings	0.646	0.354
R87.4 Abnormal immunological findings	0.646	0.354
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.646	0.354
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.646	0.354
R87.1 Abnormal level of hormones	0.646	0.354
R87.0 Abnormal level of enzymes	0.646	0.354
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.646	0.354
E85.8 Other amyloidosis	0.646	0.354
E85.3 Secondary systemic amyloidosis	0.646	0.354
E85.2 Heredofamilial amyloidosis, unspecified	0.646	0.354
E85.1 Neuropathic heredofamilial amyloidosis	0.646	0.354
E85.0 Nonneuropathic heredofamilial amyloidosis	0.646	0.354
M25.49 Effusion of joint (Site unspecified)	0.645	0.355
M25.48 Effusion of joint (Other)	0.645	0.355
M25.44 Effusion of joint (Hand)	0.645	0.355
M25.43 Effusion of joint (Forearm)	0.645	0.355
M25.42 Effusion of joint (Upper arm)	0.645	0.355
M25.41 Effusion of joint (Shoulder region)	0.645	0.355
M25.40 Effusion of joint (Multiple sites)	0.645	0.355
T79-T79 Certain early complications of trauma	0.644	0.356
E16.9 Disorder of pancreatic internal secretion, unspecified	0.643	0.357
E16.8 Other specified disorders of pancreatic internal secretion	0.643	0.357
E16.4 Abnormal secretion of gastrin	0.643	0.357
E16.3 Increased secretion of glucagon	0.643	0.357
E16.1 Other hypoglycaemia	0.643	0.357
E16.0 Drug-induced hypoglycaemia without coma	0.643	0.357
M86-M90 Other osteopathies	0.643	0.357
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.642	0.358
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.642	0.358
D46.9 Myelodysplastic syndrome, unspecified	0.642	0.358
Q82 Other congenital malformations of skin	0.642	0.358
S14 Injury of nerves and spinal cord at neck level	0.642	0.358
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.641	0.359
M81.96 Osteoporosis, unspecified (Lower leg)	0.641	0.359
M81.94 Osteoporosis, unspecified (Hand)	0.641	0.359
M81.93 Osteoporosis, unspecified (Forearm)	0.641	0.359
M81.92 Osteoporosis, unspecified (Upper arm)	0.641	0.359
M81.91 Osteoporosis, unspecified (Shoulder region)	0.641	0.359
M79.60 Pain in limb (Multiple sites)	0.641	0.359
M77.1 Lateral epicondylitis	0.640	0.360
E10.8 With unspecified complications	0.640	0.360
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.638	0.362
V20-V29 Motorcycle rider injured in transport accident	0.638	0.362
M75 Shoulder lesions	0.637	0.363
C66 Malignant neoplasm of ureter	0.637	0.363
M31.3 Wegener's granulomatosis	0.636	0.363
Y86 Sequelae of other accidents	0.635	0.365
Y35-Y36 Legal intervention and operations of war	0.635	0.365
Y10-Y34 Event of undetermined intent	0.635	0.365
X85-X99 Assault	0.635	0.365
X30-X39 Exposure to forces of nature	0.635	0.365
X00-X09 Exposure to smoke, fire and flames	0.635	0.365
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.635	0.365
W75-W84 Other accidental threats to breathing	0.635	0.365
W65-W74 Accidental drowning and submersion	0.635	0.365
V98-V99 Other and unspecified transport accidents	0.635	0.365
V95-V97 Air and space transport accidents	0.635	0.365
V90-V94 Water transport accidents	0.635	0.365
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.635	0.365
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.635	0.365
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.635	0.365
V01-V09 Pedestrian injured in transport accident	0.635	0.365
S30.1 Contusion of abdominal wall	0.635	0.365
M42 Spinal osteochondrosis	0.634	0.366
M40 Kyphosis and lordosis	0.634	0.366
C97 Malignant neoplasms of independent (primary) multiple sites	0.634	0.366
D07.5 Prostate	0.634	0.366
C15 Malignant neoplasm of oesophagus	0.634	0.366
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.633	0.367
H90.2 Conductive hearing loss, unspecified	0.633	0.367
D61 Other aplastic anaemias	0.633	0.367
T90.2 Sequelae of fracture of skull and facial bones	0.633	0.367
S43.1 Dislocation of acromioclavicular joint	0.632	0.368
Q38 Other congenital malformations of tongue, mouth and pharynx	0.632	0.368
M24.67 Ankylosis of joint (Ankle and foot)	0.631	0.369
M25.6 Stiffness of joint, not elsewhere classified	0.631	0.369
X20-X29 Contact with venomous animals and plants	0.630	0.370
C45 Mesothelioma	0.630	0.370
G80-G83 Cerebral palsy and other paralytic syndromes	0.630	0.370
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.630	0.370
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.630	0.370
M85.84 Other specified disorders of bone density and structure (Hand)	0.630	0.370
M85.83 Other specified disorders of bone density and structure (Forearm)	0.630	0.370
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.630	0.370
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.630	0.370
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.630	0.370
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.629	0.371
T43.5 Other and unspecified antipsychotics and neuroleptics	0.629	0.371
T09 Other injuries of spine and trunk, level unspecified	0.628	0.372
T13 Other injuries of lower limb, level unspecified	0.628	0.372
M94 Other disorders of cartilage	0.628	0.372
M93 Other osteochondropathies	0.628	0.372
S49 Other and unspecified injuries of shoulder and upper arm	0.627	0.372
M35 Other systemic involvement of connective tissue	0.627	0.373
T91.9 Sequelae of unspecified injury of neck and trunk	0.627	0.373
T50.8 Diagnostic agents	0.626	0.373
T50.7 Analeptics and opioid receptor antagonists	0.626	0.373
T50.6 Antidotes and chelating agents, not elsewhere classified	0.626	0.373

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations